Digital Commons Network^™

Entrustable Professional Activities In Hematopathology Pathology Fellowship Training: Consensus Design And Proposal, Kristie White, Julianne Qualtieri, Elizabeth L. Courville, Rose C. Beck, Bachir Alobeid, David R. Czuchlewski, Julie Teruya-Feldstein, Lorinda A. Soma, Sonam Prakash, Dita Gratzinger

Pathology Research and Scholarship

Hematopathology fellowship education has grown in complexity as patient-centered treatment plans have come to depend on integration of clinical, morphologic, immunophenotypic, molecular, and cytogenetic variables. This complexity is in competition with the need for timely hematopathology care with stewardship of patient, laboratory, and societal resources. Accreditation Council for Graduate Medical Education Milestones provide a guidance document for hematopathology training, but fellows and their educators are in need of a simple framework that allows assessment and feedback of growth toward independent hematopathology practice. Entrustable professional activities provide one such framework, and herein, we provide proposed Hematopathology Fellowship Entrustable Professional Activities based …

Performance Of An Affordable Urine Self-Sampling Method For Human Papillomavirus Detection In Mexican Women, Rubí Hernández-López, Luis Hermosillo, Leith León-Maldonado, Rafael Velázquez-Cruz, Leticia Torres-Ibarra, Eduardo Lazcano-Ponce, Attila Lörincz, Cosette M. Wheeler, F Xavier Bosch, Jack Cuzick, Berenice Rivera-Paredez, Belinda Nedjai, Jorge Salmerón

Pathology Research and Scholarship

INTRODUCTION: Urine self-sampling for human papillomavirus (HPV)-based cervical cancer screening is a non-invasive method that offers several logistical advantages and high acceptability, reducing barriers related to low screening coverage. This study developed and evaluated the performance of a low-cost urine self-sampling method for HPV-testing and explored the acceptability and feasibility of potential implementation of this alternative in routine screening.

METHODS: A series of sequential laboratory assays examined the impact of several pre-analytical conditions for obtaining DNA from urine and subsequent HPV detection. Initially, we assessed the effect of ethylaminediaminetetraacetic acid (EDTA) as a DNA preservative examining several variables including EDTA …

Primary Temporal Bone Meningioma Presenting As Chronic Mastoiditis And Sigmoid Sinus Thrombosis: Report Of A Case With Literature Analysis, Mary Torrez, Edgar Fischer, Shweta Agarwal

Pathology Research and Scholarship

Primary extra cranial meningioma of the ear and temporal bone are exceedingly rare, making up less than 1% of all meningiomas. Histologically, they are indistinguishable from their intracranial counterpart. The histopathologic diagnosis is often challenging, and the differential diagnosis for neoplasms in this unusual location is quite extensive. We report a 64-year-old male patient with history of seizures who presented with coalescing mastoiditis and sigmoid sinus thrombosis. CT and MRI findings were suggestive of a chronic inflammatory process. Operative findings included a flesh-colored mass extending from the mastoid antrum posteriorly towards the Sigmoid sinus. Intraoperative consultation was requested, yielding a …

Coalition For Prisoners' Rights Newsletter, Vol. 46-C, No. 2, Coalition For Prisoners' Rights

Coalition for Prisoners' Rights Newsletters

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The Least Read Part of the Newsletter

"La Colina Escalamos"

Resources & Information

Hslic Annual Report Fy2020-21, University Of New Mexico Health Sciences Library And Informatics Center

HSLIC Annual Reports

No abstract provided.

“Preservative Of All Other Rights”: Voting And Social Justice In The Post-Trump Era, Vinay Harpalani

Faculty Scholarship

As social justice advocates rejoice over Donald Trump’s defeat and look for paths forward, the biggest lesson comes from the 2020 presidential election itself. The right to vote is “preservative of all other rights[,]” and this past year underscored its importance more than ever. In the midst of the COVID-19 pandemic, high voter turnout—and especially high Black voter turnout—propelled Joe Biden to victory. Even as the Electoral College and partisan gerrymandering continue to undermine the popular will, America’s changing demographics favor people of color and progressives. Moreover, the elected branches of government have become more significant because Trump packed the …

Neural Network Based Occupancy Prediction Using Patterns Detected In Wifi Occupancy, Krishna Chaitanya Jagadeesh Simma, Thomas P. Caudell, Susan M. Bogus

Civil Engineering Faculty Publications

The role of occupants in building energy management is well established. Occupant information from commercial buildings can function as a metric for the heating, ventilation, and air conditioning (HVAC) loads. Predicting these loads ahead in time could aid in setting up HVAC protocols to minimize wasteful energy demand and improve occupant comfort. To this extent, several frameworks were proposed that use occupancy data collected from commercial office buildings and graduate student offices to predict occupancy. However, the occupancy data collected in these frameworks are controlled and have limited complexity compared to larger commercial spaces such as airports, libraries, lecture halls, …

Bubonic Plague: Public Health Warnings From An Ancient Disease, Mikenzie E. Chessman

2022 Award Winners

No abstract provided.

Overlapping Roles Of Nadph Oxidase 4 (Nox4) For Diabetic And Gadolinium-Based Contrast Agent-Induced Systemic Fibrosis-Animal Equivalent Dosing Of Gadolinium-Based Contrast Agents Supplementary Figure 2, Francesca Bruno, Joshua Deaguero, Catherine Do, Doug Yoon Lee, Chunyan Tan, G Patricia Escobar, Brent Wagner

The Kidney Institute of New Mexico

Supplementary figure for the forthcoming publication entitled “Overlapping roles of NADPH Oxidase 4 (Nox4) for diabetic and gadolinium-based contrast agent-induced systemic fibrosis”. Supplementary Figure 2 demonstrates renal changes induced by gadolinium-based contrast agent treatment and experimental diabetes. Photomicrographs analyzed by a blinded veterinary pathologist.

Bad Apples Or A Rotten Tree: Ameliorating The Double Pandemic Of Covid-19 And Racial Economic Inequality, Nathalie Martin

Faculty Scholarship

Black Lives Matter signs pepper our rural, middle class neighborhood. The lawn signs raise a fundamental question: if Black Lives Matter, what will it take to reverse the longstanding trend that has left many dead and so many others, perhaps all others, suffering? What will it take to create some semblance of equality and equity across racial lines in America?

Part I of this essay discusses race and Covid 19. It reviews and updates statistics on Covid deaths and race, and discusses some of the reasons for the racial disparities in Covid deaths. Part II briefly reviews the stratification of …

Rapid Deployment Of A Statewide Covid-19 Echo Program For Frontline Clinicians: Early Results And Lessons Learned., Anna L. Steeves-Reece, Nancy C Elder, Tuesday A Graham, Miriam L Wolf, Isabel Stock, Melinda M Davis, Ronald D Stock

Project ECHO Bibliography

No abstract provided.

Prenatal Alcohol Exposure Enhances Morphine-Mediated Toll Like Receptor (Tlr)-4 Actions And Paradoxically Prolongs Nerve Injury-Induced Pathological Pain, Shahani Noor, Melody S. Sun, Chaselyn D. Ruffaner-Hanson, Monique V. Nysus, Diane C. Jimenez, Fernando F. Valenzuela, Erin D. Milligan

Brain & Behavioral Health Research Day

Our prior work demonstrates that adult prenatal alcohol exposed (PAE) rats with minimal nerve injury develop allodynia (pathological light touch sensitivity) in concert with aberrant peripheral-spinal glial and immune activation. Nerve-injured PAE rats display heightened proinflammatory cytokine production (IL-1β, TNF-α, CCL2) typically produced following activation of innate immune receptors, TLR4 and Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasomes. This suggests that PAE-related adaptations prime peripheral macrophages and central nervous system (CNS) glia to over-respond to subtle challenges through exaggerated TLR4 and NLRP3 inflammasome reactivity. Interestingly, morphine, a standard opioid pain therapeutic, binds the μ-opioid receptor and also glial …

Santa Clara Pueblo V. Martinez In The Evolution Of Federal Law, Richard B. Collins

Tribal Law Journal

Few Indian law decisions have evoked as much scholarly attention as Santa Clara Pueblo.1 Shepard's pulls up over 1000 law review references, and Google reports almost 3,000,000 hits.2 It is a major case in all Indian law treatises and casebooks and is important in several other books.3 Most analyze the decision as an event and focus on its principal holding, denying a federal cause of action for civil enforcement of the Indian Civil Rights Act.4 Policy discussions parse tribal sovereignty and discrimination against women.

Planning And Hosting A Virtual Science-Fiction Event Series, Holly M. Surbaugh, Glenn Koelling

University Libraries & Learning Sciences Faculty and Staff Publications

As the University of New Mexico responded to the coronavirus pandemic with emergency building closures and a shift to online services, the University Libraries faced challenges making and maintaining personal connections with users in the absence of face-to-face contact. Recognizing that necessary public health restrictions isolated all students, faculty, and staff to some extent, a science librarian and an English librarian collaborated to develop a series of three Zoom-facilitated programs that provided fun activities (i.e., a movie watch party, a book discussion, and a team trivia game) to engage a socially distanced campus community while highlighting various library resources. They …

A Call To Action For Librarians: Countering Conspiracy Theories In The Age Of Qanon, Stephanie Beene, Katie Greer

University Libraries & Learning Sciences Faculty and Staff Publications

Librarians empower learners to become discerning citizens through a set of diverse skills and literacies. To cultivate critical thinkers, librarians continue to build innovative practices, even as technology rapidly evolves. However, the pervasiveness of misinformation and disinformation, most recently seen in the conspiratorial worldviews of QAnon, challenges librarians to center critical thinking in their information literacy praxis. In this article, we provide a concise overview of QAnon and the problems that contemporary internet conspiracy theories like it pose. We offer an epistemological shift for information literacy, from heuristics to mindsets and behaviors, drawing on disciplines external to librarianship. Finally, we …

Digital Image Analysis For The Detection Of Group B Streptococcus From Chromid Strepto B Medium Using Phenomatrix Algorithms, Justin Baker, Karen Timm, Matthew Faron, Nathan Ledeboer, Karissa Culbreath

Pathology Research and Scholarship

Group B Streptococcus (GBS) can be found to colonize about 25% of all healthy, adult women and is the leading infectious cause of early neonatal morbidity and mortality in the United States. This study evaluated the clinical performance of PhenoMatrix (PM) chromogenic detection module (CDM) digital imaging software in detection of GBS from LIM broth plated on ChromID Strepto B chromogenic medium (ChromID) using the WASP automated processor. The performance of the PM CDM was compared to manual culture review of the digital images and molecular detection of GBS. ChromID alone had a sensitivity and specificity of 84.5% and 94.7%, …

Wagon Tracks Volume 35, Issue 1 (November 2020), Santa Fe Trail Association

Wagon Tracks

Contents

2 On the Cover: Sending Them Off: Kit Carson and the Utes: 1843. by Ron Kil

4 Insights from your President

5 Joanne’s Jottings

7 Trail News, Education and Jr. Wagon Master

8 2021 Symposium by Dr. Michael L. Olsen and Harry C. Myers

13 SFTA Awards and Hall of Fame

16 The Diary of Pedro Ignacio Gallego: Meeting Becknell

25 Preservation Efforts on the Santa Fe Trail by Jere L. Krakow

10 The Story behind the Painting, continued

11 Historical Painting: Taking Your Best Shot by Ruth Friesen

31 Book Review: Lifelines: The Bowen Love Letters, compiled …

Dissecting Regulation Mechanism Of Interdomain Electron Transfer In Nitric Oxide Synthases, Huayu Zheng

Chemistry and Chemical Biology ETDs

Nitric oxide (NO) is generated by one of the three isoforms of mammalian NO synthases (NOSs), neuronal, endothelial and inducible NOS (nNOS, eNOS, and iNOS, respectively). Dysregulated NOS is implicated in pathologies of numerous severe diseases including Alzheimer and Parkinson’s diseases. Molecular mechanisms of NOS regulation, once fully understood, are potentially key targets for development of selective new pharmaceuticals for treating these diseases that currently lack effective treatments.

Despite recent developments, there are significant gaps in current understanding of the regulation mechanism of the FMN-heme interdomain electron transfer (IET), an essential step in NOS, by its key regulators such as …

Role Of The Acid Sensing Ion Channel 1a In The Systemic Circulation, Selina M. Garcia

Biomedical Sciences ETDs

Acid-sensing ion channel 1a (ASIC1a) is a non-selective cation channel that is expressed in vascular smooth muscle cells. However, little is known about the contribution of ASIC1a to vascular reactivity and cardiovascular homeostasis. We have previously shown that ASIC1a contributes to pulmonary vascular smooth muscle cell (VSMC) Ca²⁺ entry and vasoconstriction as well as chronic hypoxia-induced pulmonary hypertension. However, a role of ASIC1a in the systemic circulation is unclear. Previous reports have shown that ASIC1a is expressed in femoral and cerebral arteries, however, these studies suggest that ASIC1a contributes to vascular reactivity through neuronal regulation rather than vascular. Therefore, …

Numerical Evaluation Of Effective Thermal Response Of Heterogeneous Materials, Kevin W. Irick

Mechanical Engineering ETDs

Heterogeneity in materials leads to increased complication of physics, at the level or scale where heterogeneity exists, making analysis and material behavior predictions more difficult. As a result of the intricate descriptions or understanding of the physics required to determine the behavior of a heterogenous material or system, practitioners frequently prefer the use of effective properties or responses. This body of work is dedicated to performing computational analyses on the thermal behavior of heterogeneous materials and evaluating the corresponding analyses using formal verification approaches. Custom finite element method code was used for solving the heat equation in a variety of …

Cognitive Radios For Self-Aware And Spectrum-Agile Communications Over Wideband Spectrum, Mohamed A. Aref

Electrical and Computer Engineering ETDs

In this dissertation, we introduce a novel cognitive engine design for intelligent, self-aware and spectrum-agile communications. The targeted cognitive radio (CR) has sensing and learning abilities that incorporate advanced signal processing and machine/deep learning (ML/DL) techniques. It can operate over a heterogeneous wideband spectrum that is much wider than the ones proposed in the literature, most likely covering several hundreds of MHz. It has the ability to detect existing signals in the surrounding RF environment and identify their origins. Furthermore, it cognitively uses channel selection, transmit power control and interference cancellation to adapt its communications mode in response to observed …

New Mexico In Depth Interviews Vinay Harpalani: Complexity Of Colorism, Vinay Harpalani, Claudia Silva

Faculty Scholarship

“Our discourse on race in this country has largely been framed around black or white,” said University of New Mexico civil rights law professor Vinay Harpalani.

But assumptions about varying shades of skin color can, for example, lead someone who is Indian, like himself, to be mistaken as Hispanic, he said.

Academics who’ve studied racial discrimination say discrimination based on a person’s skin-tone exists across many racial and ethnic groups and generally manifests as a systematic preference for lighter skin over darker skin.

Harpalani explains it can be the other way around in some instances, such as the bullying Clark …

Virtual And In Vitro Antiviral Screening Revive Therapeutic Drugs For Covid-19, Giovanni Bocci, Steven B. Bradfute, Chunyan Ye, Matthew J. Garcia, Jyothi Parvathareddy, Walter Reichard, Surekha Surendranathan, Shruti Bansal, Cristian G. Bologa, Douglas J. Perkins, Colleen B. Jonsson, Tudor I. Oprea, Larry A. Sklar

Pathology Research and Scholarship

The urgent need for a cure for early phase COVID-19 infected patients critically underlines drug repositioning strategies able to efficiently identify new and reliable treatments by merging computational, experimental, and pharmacokinetic expertise. Here we report new potential therapeutics for COVID-19 identified with a combined virtual and experimental screening strategy and selected among already approved drugs. We used hydroxychloroquine (HCQ), one of the most studied drugs in current clinical trials, as a reference template to screen for structural similarity against a library of almost 4000 approved drugs. The top-ranked drugs, based on structural similarity to HCQ, were selected for in vitro …

Climate Change: Increased Potential For Fire Disaster In Taos, New Mexico, Matthew F. Vigil

Climate Change and Public Health Preparedness

No abstract provided.

Performance Improvements For Next Generation Falling Particle Receiver Systems, Nathan R. Schroeder

Mechanical Engineering ETDs

Falling particle receiver (FPR) systems are a rapidly developing technology for concentrating solar power applications. Solid particles are used as both the heat transfer fluid and thermal energy storage media. Through the direct solar irradiation of the solid particles, flux and temperature limitations of tube-bundle receives can be overcome leading to higher operating temperatures and energy conversion efficiencies. Particle residence time, curtain opacity, and curtain stability affect the performance of FPR designs. As the particles fall through the receiver the curtain accelerates, increasing its transmissivity thus decreasing the amount of energy absorbed. Multistage release trough structures catch and release the …

Farmers’ Place-Based Discourse About Water Relations: Ways Of Knowing Water And Multispecies Survival, Jeffrey Alan Hoffmann

Communication ETDs

The present study looks at farmers’ discourse about water and water relations. Through qualitative interviews using the method of cultural discourse analysis (CuDA), and the framework of ecocultural dialectics, the study reveals how, as farmers talk about water, they also make explicit and implicit arguments about specific cultural relations with the biosphere, as well as the role of identity, place, and power in designing and implementing agricultural solutions to ecological and social problems. I argue that the contradictions in how farmers discursively envision the problems of water pollution and scarcity, as well as solutions to those problems in their farming …

Theoretical And Experimental Studies Of The Emission Of Electromagnetic Radiation By Superluminal Polarization Currents, Andrea Caroline Schmidt-Zweifel

Electrical and Computer Engineering ETDs

Maxwell’s equations establish that patterns of electric charges and currents can be animated to travel faster than the speed of light in vacuo, c, and that these superluminal distribution patterns emit tightly focused packets of electromagnetic radiation that are fundamentally different from the emissions by previously known sources -- on Earth and in the Universe. This dissertation introduces a practical faster-than-light emitter: The superluminal polarization current antenna. Such devices use a polarization current that travels faster than c to give rise to electromagnetic radiation, a technique known as the vacuum Čerenkov effect. In what is to follow, the theoretical and …

Full Issue (Fall 2020)

Intersections: Critical Issues in Education

No abstract provided.

Ibram X. Kendi's How To Be An Antiracist, Quatez Scott

Intersections: Critical Issues in Education

This book review of Ibram X. Kendi’s How to Be an Antiracist (2019) addresses the importance of exploring race relations in the U.S. from a framework that focuses on racial policies. Commonly referred to as “systemic racism” and “institutional racism”, racist policies maintain racial inequities. Antiracists aim to eliminate those racial policies. Kendi’s ability to address these issues head on with deeply researched historical narratives brings light to the ways racial policies are reinforced, which reproduce racist ideas. This book drives straight to the heart of racial challenges and takes a new approach at examining how and why humans should …

Between The Visceral And The Lie : Lessons On Teaching Violence, Brian Gibbs

Intersections: Critical Issues in Education

Drawing from two qualitative case studies, one researching how teachers teach about war to the children of soldiers and the other examining how teachers teach lynching near historic lynching sites, this critical phenomenological study weighs how much horror and how much hope should be taught if the aim of the instruction is a liberating education. The author argues that a balance of both is necessary. Students cannot be left in the hopelessness of knowledge alone but must be taught how to engage their world with the possibility of making change.