Digital Commons Network^™

Implementing Evidence-Informed Practices To Make Schools Safer And More Supportive Of Sexual And Gender Minority Youth, Daniel Shattuck, Janie L Hall, Elizabeth Dickson, Amy E Green, Mary M Ramos

Pediatrics Research and Scholarship

No abstract provided.

Fatigue And Its Association With Social Participation, Functioning, And Quality Of Life In Systemic Sclerosis, Susan L. Murphy, Anna L. Kratz, Daniel Whibley, Janet L. Poole, Dinesh Khanna

Pediatrics Research and Scholarship

OBJECTIVE: Fatigue is consistently ranked as one of the most problematic symptoms of systemic sclerosis (SSc), but the impact of fatigue on daily life is not well characterized. The purpose of this study was to examine the contribution of fatigue to deficits in social participation, functioning, and quality of life.

METHODS: Baseline data from a sample undertaking a clinical trial were utilized (n = 267). Fatigue, pain interference, depressive symptoms, physical function, and social participation were assessed by measures from the Patient-Reported Outcomes Measurement Information System. Hierarchical linear regressions were performed to determine the unique contribution of fatigue to social …

Surveillance Systems For Monitoring Cervical Cancer Elimination Efforts: Focus On Hpv Infection, Cervical Dysplasia, Cervical Screening And Treatment., Julia M L Brotherton, Cosette Wheeler, Gary M. Clifford, Miriam Elfström, Marion Saville, John Kaldor, Dorothy A. Machalek

Pathology Research and Scholarship

In order to achieve the global elimination of cervical cancer as a public health problem, close surveillance of progress in public health and clinical activities and outcomes across the three pillars of vaccination, screening and treatment will be required. Surveillance should ideally occur within an integrated system that is planned, funded, and regularly evaluated to ensure it is providing timely, accurate and relevant feedback for action. In this paper, we conceptualise the main public health surveillance objectives as process and outcome measures in each of the three pillars. Process measures include coverage/participation measures for vaccination, screening and treatment alongside the …

Disparities In Sleep Health And Potential Intervention Models: A Focused Review., Martha E. Billings, Robyn T. Cohen, Carol M. Baldwin, Dayna A. Johnson, Brian N. Palen, Sairam Parthasarathy, Sanjay R. Patel, Maureen Russell, Ignacio E. Tapia, Ariel A. Williamson, Sunil Sharma

Project ECHO Bibliography

Disparities in sleep health are important but underrecognized contributors to health disparities. Understanding the factors contributing to sleep heath disparities and developing effective interventions are critical to improving all aspects of heath. Sleep heath disparities are impacted by socioeconomic status, racism, discrimination, neighborhood segregation, geography, social patterns, and access to health care as well as by cultural beliefs, necessitating a cultural appropriateness component in any intervention devised for reducing sleep health disparities. Pediatric sleep disparities require innovative and urgent intervention to establish a foundation of lifelong healthy sleep. Tapping the vast potential of technology in improving sleep health access may …

Perceived Critical Success Factors For Native American And Non-Native American Pre-Licensure Nursing Students In Northern New Mexico, Karen E. Nielsen

Doctor of Nursing Practice Scholarly Projects

Considering the consistent healthcare system load demands, nursing shortages persist, especially in remote areas of the United States. It is vital that students interested in attending nursing school and working in their home communities have expanded nursing program access and supports in order to supply the necessary nursing workforce in remote areas. Lack of diversity in the nursing profession weakens healthcare delivery. Native Americans are underrepresented as nursing students and employed nurses. Measures to provide a more diverse workforce should concentrate on recruitment, retention, and graduation rates of underrepresented minority nursing students. Limited research is available surrounding Native American nursing …

Lorenzo Romero-Ramos Oral History Interview February 23rd, 2021, Henry B. Hammel

Oral Histories HIST300, Spring 2021

Oral History Interview with Lorenzo Romero-Ramos

Henry Hammel, Edgar Romero Ramos

Oral Histories HIST300, Spring 2021

I had the pleasure of interviewing one of my classmates, Henry Hamal regarding his experience during the outbreak of the Covid-19 pandemic. It was interesting to note that this event had a shunting effect on Henry’s emotional development, as he noted in his interview. It was helpful to see a different perspective regarding people’s ability to adapt, or not, to a global crisis.

Interactive Effects Of Omega-3 Polyunsaturated Fatty Acids And Secondhand Smoke In Mice And Human Subjects, Emily Wheeler, Mary Walsh-Wilcox, Meer Shah, Abinash Achrekar, Joe R. Anderson, Mary K. Walker

Research and Scholarship

Active smoking and secondhand smoke (SHS) exposure increase the risk of cardiovascular morbidity and mortality. Active smoking is associated with reduced levels of omega-3 polyunsaturated fatty acids (n-3 PUFA) and studies show that n-3 PUFA supplementation can improve smoking-induced vascular dysfunction. However, the relationship between n-3 PUFA and SHS exposure has not been studied. Fat-1 transgenic mice, which convert n-6 to n-3 PUFA, were fed diets with n-3 PUFA or without (n-6 PUFA diet), exposed to air or SHS for 4 weeks, and vasoreactivity, antioxidant indices, and omega-3 index (percent eicosapentaenoic+docosahexaenoic acids in RBC) measured. Compared to air-exposed mice, SHS …

Benefits Derived From Full Laboratory Automation In Microbiology: A Tale Of Four Laboratories, Karissa Culbreath, Heather Piwonka, John Korver, Mir Noorbakhsh

Pathology Research and Scholarship

Automation in clinical microbiology is starting to become more commonplace and reportedly offers several advantages over the manual laboratory. Most studies have reported on the rapid turnaround times for culture results, including times for identification of pathogens and their respective antimicrobial susceptibilities, but few have studied the benefits from a laboratory efficiency point of view. This is the first large, multicenter study in North America to report on the benefits derived from automation measured in full-time equivalents (FTE), FTE reallocation, productivity, cost per specimen, and cost avoidance. Pre- and post-full automation audits were done at 4 laboratories that have vastly …

Inhibition Of The Heg1-Krit1 Interaction Increases Klf4 And Klf2 Expression In Endothelial Cells, Miguel Alejandro Lopez-Ramirez, Sara Mccurdy, Wenqing Li, Mark K. Haynes, Preston Hale, Karol Francisco, Killian Oukoloff, Matthew Bautista, Chelsea H J Choi, Hao Sun, Brendan Gongol, John Y. Shyy, Carlo Ballatore, Larry A. Sklar, Alexandre R. Gingras

Pathology Research and Scholarship

The transmembrane protein heart of glass1 (HEG1) directly binds to and recruits Krev interaction trapped protein 1 (KRIT1) to endothelial junctions to form the HEG1-KRIT1 protein complex that establishes and maintains junctional integrity. Genetic inactivation or knockdown of endothelial HEG1 or KRIT1 leads to the upregulation of transcription factors Krüppel-like factors 4 and 2 (KLF4 and KLF2), which are implicated in endothelial vascular homeostasis; however, the effect of acute inhibition of the HEG1-KRIT1 interaction remains incompletely understood. Here, we report a high-throughput screening assay and molecular design of a small-molecule HEG1-KRIT1 inhibitor to uncover acute changes in signaling pathways downstream …

Fatal Self-Injury In The United States, 1999-2018: Unmasking A National Mental Health Crisis, Ian R H Rockett, Eric D. Caine, Aniruddha Banerjee, Bina Ali, Ted Miller, Hilary S. Connery, Vijay O. Lulla, Kurt B. Nolte, G Luke Larkin, Steven Stack, Brian Hendricks, R Kathryn Mchugh, Franklin M M White, Shelly F. Greenfield, Amy S B S B Bohnert, Jeralynn S. Cossman, Gail D'Onofrio, Lewis S. Nelson, Paul S. Nestadt, James H. Berry, Haomiao Jia

Pathology Research and Scholarship

BACKGROUND: Suicides by any method, plus 'nonsuicide' fatalities from drug self-intoxication (estimated from selected forensically undetermined and 'accidental' deaths), together represent self-injury mortality (SIM)-fatalities due to mental disorders or distress. SIM is especially important to examine given frequent undercounting of suicides amongst drug overdose deaths. We report suicide and SIM trends in the United States of America (US) during 1999-2018, portray interstate rate trends, and examine spatiotemporal (spacetime) diffusion or spread of the drug self-intoxication component of SIM, with attention to potential for differential suicide misclassification.

METHODS: For this state-based, cross-sectional, panel time series, we used de-identified manner and underlying …

Hope Springs Eternal: Can Project Echo Transform Nursing Homes?, Alice Bonner

Project ECHO Bibliography

No abstract provided.

Strength, Fracture Evolution, And Permeability Changes From Confined Brazilian Tests On Sandstone, Tyler Louis Hagengruber

Civil Engineering ETDs

This research reports on confined Brazilian strength tests and concurrent permeability testing on sandstone. The majority of the tests measured permeability during loading to failure in the confined extension region. Additional testing includes unloading and reloading cycles to detect the development of microcracks and the dependence of permeability on mixed stress conditions. Further testing characterizes fracture networks by observing porosity changes due to microcrack interactions before peak load. All tests involve 5 cm diameter disk-shaped, jacketed samples that are subjected to confining stresses while they are diametrically loaded. Specially designed end caps allow for gas flow measurements. The test configuration …

20210119_Hslic's Biomedical Informatics Seminar Series Presents- Nitin Verma, Msis, Tamara Wheeler

HSLIC Blog Post

No abstract provided.

Unm Hsc Education Day Agenda 2020-21, Gary Smith

HSC Education Days

No abstract provided.

Pandemics In The Media: Achieving Wellness Through Information & Resource Sharing, Fiore Casale, Christine Teng

HSC Education Days

Introduction: The COVID-19 pandemic increased uncertainty and anxiety in the lives of medical students. It is difficult to remain updated with quality information about COVID-19. Moreover, unprecedented stresses threaten student wellness. Objectives: Create an initiative to investigate and analyze domestic and international information disseminated through the media, public health responses, and popular culture. Pilot wellness techniques to ease despair related to the quantity and quality of COVID-19 information. Methods and Materials: A comprehensive overview of COVID-19 global media coverage included news articles, journals, podcasts, and documentaries. An analysis of the information was discussed amongst the group. Global public health strategies …

Strategies To Support Online Student Success, Mary Thelander Hill

HSC Education Days

Online coursework in health care professional programs was increasing prior to Covid-19 pandemic emergency online coursework, and will likely continue to expand. Numerous current strategies to improve student engagement and skill instruction are presented. Opportunities to reflect on challenges and benefits of online coursework will allow for translation from literature to curriculum development to successful instructional experiences. Incorporation of Culturally Responsive Theory will encourage online students to share their diverse knowledge and perspectives.

Creating A Database For Dermatologic Conditions In Skin Of All Colors, Sabah Osmani, Towela King, Charles Phillips, Aimee C. Smidt

HSC Education Days

The U.S. Census Bureau predicts that Hispanic, Black and other minority groups will constitute more than half of the U.S. population by 2044. It is therefore problematic that only about 10% of images in dermatology textbooks illustrate dermatologic conditions in dark skin. This paucity of adequate resources has affected physicians’ education and patient outcomes. A study several years ago found 47% of dermatologists and residents reported that their medical training on pathologies in Black skin was insufficient, and that there was a need for more training materials exhibiting Black skin. Black and Hispanic patients are also less likely to be …

The R-Enantiomer Of Ketorolac Reduces Ovarian Cancer Tumor Burden In Vivo, Martha M. Grimes, S Ray Kenney, Dayna R. Dominguez, Kathryn J. Brayer, Yuna Guo, Angela Wandinger-Ness, Laurie G. Hudson

Pathology Research and Scholarship

BACKGROUND: Rho-family GTPases, including Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42), are important modulators of cancer-relevant cell functions and are viewed as promising therapeutic targets. Based on high-throughput screening and cheminformatics we identified the R-enantiomer of an FDA-approved drug (ketorolac) as an inhibitor of Rac1 and Cdc42. The corresponding S-enantiomer is a non-steroidal anti-inflammatory drug (NSAID) with selective activity against cyclooxygenases. We reported previously that R-ketorolac, but not the S-enantiomer, inhibited Rac1 and Cdc42-dependent downstream signaling, growth factor stimulated actin cytoskeleton rearrangements, cell adhesion, migration and invasion in ovarian cancer cell lines and …

Neutrosophic Statistical Analysis Of Income Of Youtube Channels, Ishmal Shahzadi, Muhammad Aslam, Hussain Aslam

Neutrosophic Sets and Systems

No abstract provided.

Unnecessary Burdens To Post-Conviction Dna Testing: New Mexico's Post-Conviction Dna Relief Statute And Suggestions For Improvement, Samantha Catalano

Student Published Scholarship

Post-conviction DNA testing is often the last option a convicted person may have to establish that they are not guilty of a crime. New Mexico's post-conviction DNA statute requires convicted persons who seek DNA testing to claim innocence and establish that the identity of the perpetrator was an issue at trial. These requirements are currently included in many state post-conviction DNA statutes; however, some states have amended their statutes to remove these unnecessary requirements. Convicted persons who claimed self-defense, or another affirmative defense may be denied post-conviction DNA testing because of inability to claim "innocence" and because the identity of …

Capacity Building For A New Multicenter Network Within The Echo Idea States Pediatric Clinical Trials Network, Robert D. Annett, Scott Bickel, John C. Carlson, Kelly Cowan, Sara Cox, Mark J. Fisher, J Dean Jarvis, Alberta S. Kong, Jessica S. Kosut, Kurtis R. Kulbeth, Abbot Laptook, Pearl A. Mcelfish, Mary M. Mcnally, Lee M. Pachter, Barbara A. Pahud, Lee A. Pyles, Jennifer Shaw, Kari Simonsen, Jessica Snowden, Christine B. Turley, Andrew M. Atz

Pediatrics Research and Scholarship

No abstract provided.

Vacteens.Org: A Mobile Web App To Improve Hpv Vaccine Uptake, W Gill Woodall, Gregory Zimet, Alberta Kong, David Buller, Jeannyfer Reither, Lance Chilton, Valerie Myers, Randall Starling

Pediatrics Research and Scholarship

U.S. HPV vaccine uptake remains below the Healthy People 2030 goal of 80% series completion. Parental concerns and misinformation about the efficacy and safety of the Human Papillomavirus (HPV) vaccine remain, and may be addressed by digital interventions tailored to their concerns. Reported here are results from a small scale randomized trial testing a mobile web app for parents and their adolescent daughters (ages 11-14 years) encouraging HPV vaccination in New Mexico, an ethnically-diverse U.S. state.

The Role Of Lawyers In Bridging The Gap Between The Robust Federal Rights To Education And Relatively Low Education Outcomes In Guatemala, Maryam Ahranjani

Faculty Scholarship

Relative to other countries in the world and in Central America, the Guatemalan Constitution and the federal education law include a robust and detailed right to education. However, literacy rates and secondary educational attainment, particularly for Indigenous people and young women living in rural communities, remain low. The COVID-19 pandemic has only exacerbated disparities. Once children return to schools after the pandemic, the gaps will be even larger. Lawyers can play a critical role in making the strong Constitutional right to education more meaningful.

Proteopathic Tau Primes And Activates Interleukin-1ss (Il-1ss) Via Myd88- And Nlrp3-Asc-Inflammasome Dependent Pathways Cell-Autonomous To Microglia, Shanya Jiang, Nicole M. Maphis, Jessica Binder, Devon Chisholm, Lea Weston, Walter Duran, Crina Floruta, Amber Zimmerman, Michael Mandell, Stephen Jett, Eileen Bigio, Changiz Geula, Nikolaos Mellios, Jason Weick, Eicke Latz, Michael Heneka, Kiran Bhaskar

Brain & Behavioral Health Research Day

Pathological hyperphosphorylation and aggregation of tau (pTau) and neuroinflammation, driven by interleukin-1β (IL-1β), are the major hallmarks of tauopathies. Here, we show that pTau primes and activates IL-1ß. First, pTau burden co-exist with elevated IL-1β and inflammasome proteins (NLRP3 and ASC) in autopsy brains of human tauopathies. Suppression of human tau blocks both priming and activation of ASC and NLRP3 in the rTg4510 mouse model of tauopathy. Treating microglia with pTau-containing neuronal media, exosomes or purified human tau tangles causes IL-1β activation, which is NLRP3, ASC, and caspase-1-dependent.

While the microglia-restricted deletion of a common innate immune adaptor protein, MyD88 …

Ensuring Optimal Community Hiv Testing Services In Nigeria Using An Enhanced Community Case-Finding Package (Eccp), October 2019-March 2020: Acceleration To Hiv Epidemic Control., Ibrahim Jahun, Emilio Dirlikov, Solomon Odafe, Aminu Yakubu, Andrew T Boyd, Pamela Bachanas, Charles Nzelu, Gambo Aliyu, Tedd Ellerbrock, Mahesh Swaminathan

Project ECHO Bibliography

Purpose: The 2018 Nigeria HIV/AIDS Indicator and Impact Survey (NAIIS) showed Nigeria's progress toward the UNAIDS 90-90-90 targets: 47% of HIV-positive individuals knew their status; of these, 96% were receiving antiretroviral therapy (ART); and of these, 81% were virally suppressed. To improve identification of HIV-positive individuals, Nigeria developed an Enhanced Community Case-Finding Package (ECCP). We describe ECCP implementation in nine states and assess its effect.

Methods: ECCP included four core strategies (small area estimation [SAE] of people living with HIV [PLHIV], map of HIV-positive patients by residence, HIV risk-screening tool [HRST], and index testing [IT]) and four supportive strategies (alternative …

Soe And Its Contribution To The Allied War Effort During The Second World War, Etienne G. Allred

2022 Award Winners

No abstract provided.

Missing And Murdered Indigenous Women (And Children) – A Global Problem, Hevyn L. Heckes

2022 Award Winners

No abstract provided.

An Impact Evaluation Of Covid-19 Training Program: Knowledge And Awareness Of Public Health Professionals Of Province Five, Nepal, Alok K. Bohara, Swati Thapa, Siobhan K. Yilmaz, Spencer H. Mcbee

Himalayan Research Papers Archive

With the declaration of a worldwide pandemic in March 2020 (World Health Organization 2020), COVID-19 has become a primary focus of governments and public health systems across the world with increases in infection and death rates. By mid-April 2020, more than 80% of countries had imposed containment and mitigation measures. But for developing nations, the threats of this global pandemic are more acute given the lack of resources and the capacity to deal with a shock of this magnitude (Loayza 2020). Despite calling for a lockdown on March 24th, 2020 (Pradhan 2020), Nepal faces several public health challenges including limited …

Let’S Get Serious – The Clear Case For Compensating The Student Athlete – By The Numbers, Neal Newman

New Mexico Law Review

Should college athletes be compensated for their play and if so, how? The first question has been a debate for some time now. But the second question—the “how”—not so much. This writing addresses both questions in depth. With the Ed O’Bannon case that was decided back in August of 2014 and the palaver the Northwestern football team raised in their efforts to unionize, it is acknowledged that the discussions on this issue may have reached its crescendo years ago. That is until now. On September 27, 2019, Gavin Newsom, the Governor of California, signed into law Senate Bill 206. Senate …