Digital Commons Network^™

Effects Of Acute And Chronic Gut Injury On Secretory Lineage Differentiation, Roger Atanga

Biomedical Sciences ETDs

Acute and chronic injury to the gut has several detrimental consequences. However, dysregulation of secretory lineage cells is a common observation. To model acute gut injury, we use non-fissile uranium bearing dust (UBD), an environmental toxicant prevalent in communities adjacent abandoned uranium mines, majority of which are located in the Southwestern United States. Repeated exposure to environmental toxins and heavy metals has been obscurely linked to intestinal inflammation, increased susceptibility to pathogen-induced diseases, and higher incidences of colorectal cancer. However, there is no molecular evidence that non-fissile uranium can cause damage to the intestinal epithelia. Human colonoids exposed to UBD …

A Nomination For The Oliver La Farge House To The Historic Santa Fe Foundation’S Register Of Properties Worthy Of Preservation, Hayden D-L Mcafee

Architecture and Planning ETDs

647 Old Santa Fe Trail is a traditional one-story adobe house in the territorial style. Constructed in 1867, it has a long history and has played a significant role in the development of Santa Fe. Sitting on the original path of the Santa Fe Trail and later Route 66, it has witnessed over 150 years of history both outside and within its doors. It was occupied by the Pulitzer Prize winning author and respected anthropologist Oliver La Farge from 1947-1963. La Farge was an important figure in the Santa Fe community, most recognized for his novels and activism, advocating for …

Heterochiral Dna Nanotechnology For Biomedical Applications, Tracy L. Mallette

Biomedical Engineering ETDs

In the past 30 years, there have been major advancements on how to treat and diagnose disease because of the improvement and increase in accessibility of sequencing technology. Nucleic acid-based therapeutics can manipulate protein expression. Likewise, pathogens can be identified and detected with single nucleotide specificity. However, the underlying oligonucleotide technology requires protection against natural defense systems that have evolved to destroy foreign nucleic acids. Many chemical modifications that can protect nucleotides also have significant cytotoxic side effects and must be carefully designed into the strands. A novel way to protect against nuclease-mediated degradation is through the use of mirror-image, …

News Media Framing Of Disabilities In Ghana: Journalistic Practices Amidst Advocacy Calls For Change, Pamela Ofori Boateng

Communication ETDs

The study contributes to expanding scholarly research on media portrayals of people with disabilities in Ghana. Drawing on theories of framing, ableism, and intersectionality, I analyzed news stories published in Graphic.com.gh. in 2021 and 2022 to explore how the editorial practices framed people with disabilities and how framing patterns revealed change and continuity in representation. The findings affirmed a shift to using more diverse and appropriate language to represent people with disabilities more fairly and accurately; the categorization of most of the disability stories under “General News,” which suggests the significance attached to disability related stories; and the …

Queer Crises: Movements From Queerness And Feelings Of White Religion In The United States, Austin Williams Miller

Communication ETDs

Anchored by contemporary crises surrounding queer and trans people in the United States, I employ movements from queerness within an affective queer phenomenological framework to understand how arrangements of “white religion” (Schaefer, 2015, p. 63), a process whereby U.S. American Christian forms escape ideology into religious affective economies in the United States, relegate queer people “to the background… to sustain a certain direction” (Ahmed, 2006, p. 31). I assemble a queer rhetorical context analyzing white religious space in documentary film, secular sexual regulation through contemporary U.S. legal contexts around marriage, and settler colonial Christian nationalist political imaginations to critique how …

Genomic Analyses In Cornelia De Lange Syndrome And Related Diagnoses: Novel Candidate Genes, Genotype-Phenotype Correlations And Common Mechanisms, Maninder Kaur, Justin Blair, Batsal Devkota, Sierra Fortunato, Dinah Clark, Audrey Lawrence, Jiwoo Kim, Wonwook Do, Benjamin Semeo, Olivia Katz, Devanshi Mehta, Nobuko Yamamoto, Emma Schindler, Zayd Al Rawi, Nina Wallace, Jonathan J Wilde, Jennifer Mccallum, Jinglan Liu, Dongbin Xu, Marie Jackson, Stefan Rentas, Ahmad Abou Tayoun, Zhang Zhe, Omar Abdul-Rahman, Bill Allen, Moris A Angula, Kwame Anyane-Yeboa, Jesús Argente, Pamela H Arn, Linlea Armstrong, Lina Basel-Salmon, Gareth Baynam, Lynne M Bird, Daniel Bruegger, Gaik-Siew Ch'ng, David Chitayat, Robin Clark, Gerald F Cox, Usha Dave, Elfrede Debaere, Michael Field, John M Graham, Karen W Gripp, Robert Greenstein, Neerja Gupta, Randy Heidenreich, Jodi Hoffman, Robert J Hopkin, Kenneth L Jones, Marilyn C Jones, Ariana Kariminejad, Jillene Kogan, Baiba Lace, Julian Leroy, Sally Ann Lynch, Marie Mcdonald, Kirsten Meagher, Nancy Mendelsohn, Ieva Micule, John Moeschler, Sheela Nampoothiri, Kaoru Ohashi, Cynthia M Powell, Subhadra Ramanathan, Salmo Raskin, Elizabeth Roeder, Marlene Rio, Alan F Rope, Karan Sangha, Angela E Scheuerle, Adele Schneider, Stavit Shalev, Victoria Siu, Rosemarie Smith, Cathy Stevens, Tinatin Tkemaladze, John Toimie, Helga Toriello, Anne Turner, Patricia G Wheeler, Susan M White, Terri Young, Kathleen M Loomes, Mary Pipan, Ann Tokay Harrington, Elaine Zackai, Ramakrishnan Rajagopalan, Laura Conlin, Matthew A Deardorff, Deborah Mceldrew, Juan Pie, Feliciano Ramos, Antonio Musio, Antonie D Kline, Kosuke Izumi, Sarah E Raible, Ian D Krantz

Pediatrics Research and Scholarship

Cornelia de Lange Syndrome (CdLS) is a rare, dominantly inherited multisystem developmental disorder characterized by highly variable manifestations of growth and developmental delays, upper limb involvement, hypertrichosis, cardiac, gastrointestinal, craniofacial, and other systemic features. Pathogenic variants in genes encoding cohesin complex structural subunits and regulatory proteins (NIPBL, SMC1A, SMC3, HDAC8, and RAD21) are the major pathogenic contributors to CdLS. Heterozygous or hemizygous variants in the genes encoding these five proteins have been found to be contributory to CdLS, with variants in NIPBL accounting for the majority (>60%) of cases, and the only gene identified to date that results in …

Partnership For Vaccine Equity: Covid-19 And Flu Vaccine Supplement, Theresa H. Cruz, Camille Velarde

Reports & Documents

Please look below for the supplemental files:

• Executive Summary
• Spanish translation of the COVID REACH final report

The Municipal Acequias Of San Fernando De Béxar: A Working Paper, José A. Rivera Ph.D

Faculty Publications

Of the seven acequia irrigation systems constructed during the height of San Antonio’s Spanish colonial period, five were built for the benefit of the Franciscan missions and their indigenous residents: San Antonio de Valero, Nuestra Señora de la Purísima Concepción de Acuña, San José y San Miguel de Aguayo, San Juan Capistrano, and San Francisco de la Espada. In addition to the five mission acequias, other diversions from the Río de San Antonio and San Pedro Creek were constructed for civilian use within the municipality of San Fernando de Béxar, founded in 1731, now San Antonio: the San Pedro Acequia …

Advanced Quantitative Approaches To Unveil Social Inequities In Educational Contexts, Manuel J. Jiménez, Vanessa Svihla, Karl Benedict, Victor Law, Meeko Oishi

Organization, Information and Learning Sciences ETDs

Chapter 2 introduces an innovative method integrating Geographic Information Systems and Machine Learning to evaluate educational policy outcomes. This approach overcomes the limitations of traditional statistical methods and effectively analyzes complex relationships between educational data and demographic factors.

The study in Chapter 3 developed a prediction model for school report cards in New Mexico using census data and applying the methods described in Chapter 2. The accurate predictions suggested that the school accountability system disproportionately assigned failing grades to schools serving minoritized students. The study also confirmed that status measures depend more on demographics than growth measures.

The study in …

Indigenous Student Responses Of Resiliency To Adversity, Aaron Billie

Teacher Education, Educational Leadership & Policy ETDs

The purpose of this study was to analyze the responses of Indigenous students as they experience situations that are adversarial and precarious. One of the goals of this study was to empower voices of Indigenous students in providing an avenue to share their genuine stories of resilience. I served as both researcher and mentor as I applied a Navajo framework to the analysis of the data known as Nitl‘iz Saad bee Hozho Iina Sila (NSBHIS), or beautiful lifeways exist within the language of precious elements. The four areas of this framework held up the salient outcomes from the research which …

Understanding The Academic And Socio-Cultural Experiences Of Academically Underprepared Males And The Risk And Protective Factors Influencing Degree Attainment In A Community College System, Diego J. Trujillo

Teacher Education, Educational Leadership & Policy ETDs

This study aimed to identify the risk and protective factors that influence persistence, retention, and degree attainment among academically underprepared male students at a community college in Northern New Mexico. Understanding the context of developmental education was deemed crucial for this research, as open-access institutions, particularly community colleges, serve as the starting point for many students' educational journeys. Evaluating the experiences and educational pathways of these students is of great importance to address the existing achievement gaps. The research focused on understanding the experiences of these students and the factors that hindered or supported their persistence and degree completion.

By …

Electromagnetic Simulations Of The Lansce Chopper Structure, Yusuf Sahin

Electrical and Computer Engineering ETDs

Particle accelerators are important for basic research as well as in applications such as ion implantation and cancer therapy. One important accelerator is the Los Alamos Neutron Science Center (LANSCE) located at Los Alamos National Laboratory (LANL) that primarily produces neutrons for research. The beam chopper simulation described here is a study to provide better modeling of this subsystem of LANSCE. A chopper is a device in which particles are intermittently sliced and directed to a target and/or experiment. The simulations in this thesis are used to analyze the correct operating parameters of the chopper. A good chopper model can …

Hydrothermal Liquefaction Of Wastewater Sludges For Energy Resource Recovery, Carl L. Abadam

Civil Engineering ETDs

This study aims to identify how variabilities in wastewater process configurations impact the biocrude yields from sludges processed and stabilized by hydrothermal liquefaction. Clean and renewable energy sources are vital to ensure a sustainable future. However, the current consumption of fossil fuels limits the ability to achieve this goal. Hydrothermal liquefaction (HTL) is a thermochemical process that converts wet biomass to valuable biocrude oil and biochar while reducing solid masses. Wastewater sludges were sampled across three facilities with varying influent design capacities and biological treatment configurations. Lipids extracted via solvent extraction and biocrudes produced from HTL were determined gravimetrically. Relative …

Hydraulic Habitat Suitability For The Rio Grande Silvery Minnow At The Los Chavez Irrigation Outfall, New Mexico, Haley A. Ormsbee

Civil Engineering ETDs

It is essential to manage the Middle Rio Grande for aquatic species to preserve the native biodiversity of the river. During periods of low flow, endangered species such as the Rio Grande Silvery Minnow (RGSM) may get trapped in a drying reach without the ability to escape from isolated pools. Very little is known about how areas of refuge, such as irrigational outfall channels, buffer RGSM from stream flow intermittency. Hence, there is a crucial need to quantify available habitat for RGSM in areas of refuge. This study aims to make connections between flow regimes and physical-habitat conditions to help …

Role Of Endophytic Fungi On Arsenic Uptake In Solution: Insights For Bioremediation, Taylor Lillian Busch

Civil Engineering ETDs

Hazardous metals mobilized from natural deposits and mining legacy are environmental and human health concerns. The waters of our partner Native American communities affected by uranium and gold mining legacy exceed the EPA MCL of 10 µg/L arsenic (As). Bioremediation is a novel technology that uses native resources to remediate metals in the soil and groundwater. Plant-fungi symbiosis for bioremediation is widely studied, but the role of endophytic fungi in metal uptake is not well understood. The objectives of this study are to 1) determine As uptake by symbiotic endophyte Cadophora sp. and little bluestem grass (Schizachyrium scoparium) …

Identifying The Required Ecological Flow For Sediment Movement In The Río Chama: Field Data Informed Visual Spatial Model, Cristian Kremer

Civil Engineering ETDs

The continuous alteration of flow regimes in rivers has led to negative impacts on habitats and biotic communities, causing irreversible effects on river biodiversity. Implementing e-flows in management strategies can repair historical mismanagement, prevent further degradation, and restore ecosystem services. In the case of the Rio Chama, damming has altered its hydrological regime, affecting sediment transport. Experts recommend specific e-flow conditions for the Rio Chama to improve ecological conditions, in particular a bankfull discharge of 70 m³s^-1 every 2 years for sediment flushing and channel maintenance. The Río Gallina, a tributary of the Rio Chama, plays a …

Development Of The Navigator: A Lagrangian Smart Sensing System To Characterize Aquatic Ecosystems., Aashish Sanjay Khandelwal

Civil Engineering ETDs

Most freshwater aquatic studies rely on Eulerian monitoring, i.e., water quality and quantity are monitored using grab samples or semi-continuous sensors deployed at fixed cross-sections. While Eulerian monitoring is practical, it provides a limited understanding of spatial and temporal heterogeneity and their effects on environmental processes. This dissertation summarizes the design and application of The Navigator, an alternative Lagrangian monitoring system that offers cost-effective solutions for in-situ, real-time data collection in lotic and lentic freshwater ecosystems such as streams, rivers, ponds, and reservoirs. The Navigator features a suite of methods – an autonomous surface vehicle (ASV) with GPS and LTE …

An Inventory Control Model In The Framework Of Covid-19 Disruptions Considering Overage Items With Neutrosophic Fuzzy Uncertainty, Suchitra Pattnaik, Mitali Madhusmita Nayak, Pavan Kumar

Neutrosophic Sets and Systems

No abstract provided.

Application Of Neutrosophic Sets Based On Neutrosophic Negative Score Function In Medical Diagnosis, Thangaraja P, Vadivel A, John Sundar C

Neutrosophic Sets and Systems

No abstract provided.

Modelling The Progression Of Alzheimer's Disease Using Neutrosophic Hidden Markov Models, D. Nagarajan, J. Kavikumar, Mary Tom, Mufti Mahmud, S. Broumi

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Totally Semi-Continuous Functions, Md. Hanif Page, Raksha Ben, P. G. Patil

Neutrosophic Sets and Systems

No abstract provided.

Identification Of Rht (Reaching Height Transceiver) For Effective Communication Using Neutrosophic Fuzzy Soft Sets In Communication Engineering Problems, Manikandan Kh, Muthuraman Ms, Sridharan M, Sabarinathan G, Muthuraj R

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Set Hybrid Mcdm Methodology For Choosing Best Surfactant-Free Microemulsion Oils Within Performance And Emission Criteria Over A Wide Range Of Engine Loads, Ahmed Abdel-Monem, Mohammed K. Hassan, Ahmed Abdelhafeez, Shimaa S. Mohamed

Neutrosophic Sets and Systems

No abstract provided.

Selecting The Suitable Waste To Energy Technology For India Using Multimoora Method Under Pythagorean Neutrosophic Fuzzy Logic, R. Narmada Devi, S. Sowmiya, A. Anuja

Neutrosophic Sets and Systems

No abstract provided.

Application Of Neutrosophic Sets Based On Score Function In Medical Diagnosis, Thangaraja P, Vadivel A, John Sundar C

Neutrosophic Sets and Systems

No abstract provided.

Choice Of Suitable Referral Hospital To Improve The Financial Result Of Hospital Operations And Quality Of Patient Care Under A Neutrosophic Environment, Ahmed Abdelhafeez, Ahmed Abdel-Monem, Alber S. Aziz, Alshaimaa A. Tantawy

Neutrosophic Sets and Systems

No abstract provided.

State Of Art Of Plithogeny Multi Criteria Decision Making Methods, S. Sudha, Nivetha Martin, Florentin Smarandache

Neutrosophic Sets and Systems

No abstract provided.

Hsc Connects Newsletter - July 28, 2023, Unm Hsc Communications

HSC Connects Newsletters

Weekly newsletter of the UNM Health Sciences Center.

Adaptive Gps Antenna Array Beam Nulling Effectiveness Under Varying Antenna Element Positioning, Aadesh Neel

Electrical and Computer Engineering ETDs

Global Positioning System (GPS) is an essential part of modern life but is susceptible to same frequency jamming. GPS jamming can add excessive noise to a received low power signal and have the capability to change or completely distort information being sent through the GPS signal. Adaptive antenna arrays have long since been a solution to mitigating GPS jamming via beamnulling algorithms. However, there is little research on the effectiveness of these beamnulling algorithms under varying element positioning. In this work, an adaptive antenna array, consisting of Right-Hand Circularly Polarized (RHCP) nearly square GPS antenna elements, was constructed and tested …

Carrie Tingley Hospital Records & William Minear Papers: Seed Funding Project, Laura J. Hall, Jonathan M. Pringle

Posters and Presentations

No abstract provided.