Secondary Electron Yield Measurements On Materials Of Interest To Vacuum Electron Communication Devices, Talal Ahmed Malik

Electrical and Computer Engineering ETDs

Microwave vacuum electron devices are a critical part of communication satellite payloads. The phenomenon of multipactor breakdown (MPB) can cause the performance of these devices to deteriorate, including their partial or total destruction. MPB depends on a number of factors, including the secondary electron yield (SEY) of materials used within the device. The process of electron multiplication, which leads to breakdown, initiates with the impact of primary electrons on target surfaces, and the resonance of free electrons within an oscillating electromagnetic field under vacuum conditions. Therefore, it is of interest to find materials and surface treatment methods that exhibit low …

Painted Over In Brown: Border Art As Visual Discourse Of Resistance, Nicole Rivera

Communication ETDs

Borders are created to colonize both land and body. The politically constructed line between the United Stated (U.S.) and Mexico impose physical and emotional trauma through border militarization and immigration policies that consequently separate families and criminalize individuals. Rhetoric centering xenophobic divisions has normalized violence against brown bodies. The relentless effort to continue this divide has led to a genre of art that manifests on the border wall. Artist use the U.S.-Mexico border as a canvas to resist and challenge migratory criminalization by visualizing their opinions to redefine this 1,954-mile line. This research is centered in the study of communication …

Developing A Virus-Like Particle (Vlp)-Based Vaccine For Neisseria Gonorrhoeae, Ashvini Vaidya

Biomedical Sciences ETDs

Neisseria gonorrhoeae (Ng) is a sexually transmitted bacterium that infects human reproductive mucosal surfaces. Due to the risk of complications in untreated cases and evolving antibiotic resistance, a prophylactic vaccine is critical for preventing infection. There are four Ng outer-membrane proteins that contribute to Ng survival and resistance: PorB, BamA, TbpA, and MtrE. Each protein contains surface-exposed loops that are targets of bactericidal antibodies. Vaccines were developed by displaying Ng epitopes on the surface of bacteriophage virus-like particles (VLP). VLPs are immunogenic, multivalent, self-assembling complexes composed of viral structural proteins. Antigenic peptide sequences can be displayed on the surface …

Speech Characteristics Of Professional Fighters, Sofiya Krasilshchikova, Amy Neel Ph.D., Jessica Dawn Richardson Ph.D., Rick Arenas Ph.D., Lauren Bennett Ph.D., Sarah Banks Ph.D., Charles Bernick Ph.D.

Speech and Hearing Sciences ETDs

The aims of this project were to accurately measure and describe speech characteristics of professional fighters; and to analyze the future potential of using speech characteristics as biomarkers for acquired neurogenic decline or chronic traumatic encephalopathy (CTE). The Professional Fighters Brain Health Study (PFBHS) is a longitudinal project investigating the effect of repeated head trauma in professional combatants. The PFBHS provided recorded speech samples for this project. This study measured accurate speech characteristics of 102 professional boxers and mixed martial artists and compared these results to a group of 27 age-matched healthy controls. Analysis revealed a significant difference in articulation …

The Origins And Development Of Textile Writing In Peru, William Mead Cheek

Art & Art History ETDs

Scholars once considered Inka khipus (14^th-16^th CE) to be a technological development unique to the Inka Empire. We now know that the earlier central Andean Wari (6^th-11^th CE) also made use of khipus, calling into question the Inka primacy of the technology. Understanding the origins and transformation of khipu notation in the Andes sheds light on the ways that information technologies figured into Andean state formation and administration, and impacts larger understandings of how tactile notational systems develop into writing and information storage. This study articulates how, just as the Inka inherited khipu technology …

Sars-Cov-2 Reverse Genetics Reveals A Variable Infection Gradient In The Respiratory Tract, Yixuan J. Hou, Kenichi Okuda, Caitlin E. Edwards, David R. Martinez, Takanori Asakura, Kenneth H. Dinnon, Takafumi Kato, Rhianna E. Lee, Boyd L. Yount, Teresa M. Mascenik, Gang Chen, Kenneth N. Olivier, Andrew Ghio, Longping V. Tse, Sarah R. Leist, Lisa E. Gralinski, Alexandra Schäfer, Hong Dang, Rodney Gilmore, Satoko Nakano, Ling Sun, M Leslie Fulcher, Alessandra Livraghi-Butrico, Nathan I. Nicely, Mark Cameron, Cheryl Cameron, David J. Kelvin, Aravinda De Silva, David M. Margolis, Alena Markmann, Luther Bartelt, Ross Zumwalt, Fernando J. Martinez, Steven P. Salvatore, Alain Borczuk, Purushothama R. Tata, Vishwaraj Sontake, Adam Kimple, Ilona Jaspers, Wanda K. O'Neal, Scott H. Randell, Richard C. Boucher, Ralph S. Baric

Pathology Research and Scholarship

The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease 2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a GFP reporter virus to explore severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis and a luciferase reporter virus to demonstrate sera collected from SARS and COVID-19 patients exhibited limited cross-CoV neutralization. High-sensitivity RNA in situ mapping revealed the highest angiotensin-converting enzyme 2 (ACE2) expression in the nose with decreasing expression throughout the lower respiratory tract, paralleled by a striking gradient of SARS-CoV-2 infection in proximal (high) versus distal (low) pulmonary epithelial cultures. COVID-19 …

"A Comparison Of Variable Selection Methods Using Bootstrap Samples From Environmental Metal Mixture Data", Paul-Yvann Djamen

Mathematics & Statistics ETDs

In this thesis, I studied a newly developed variable selection method SODA, and three customarily used variable selection methods: LASSO, Elastic net, and Random forest for environmental mixture data. The motivating datasets have neuro-developmental status as responses and metal measurements and demographic variables as covariates. The challenges for variable selections include (1) many measured metal concentrations are highly correlated, (2) there are many possible ways of modeling interactions among the metals, (3) the relationships between the outcomes and explanatory variables are possibly nonlinear, (4) the signal to noise ratio in the real data may be low. To compare these methods …

Danzantes Aztecas Y Promotoras Tradicionales: The Ritual Performances And Identity Politics Of A Mexican American Danzantes Aztecas Y Promotoras Tradicionales: The Ritual Performances And Identity Politics Of A Mexican American Ceremonial Community, Dina K. Barajas

American Studies ETDs

This dissertation is an ethnographic study which examined the ritual performances of an interconnected Mexican American and Mexican immigrant danza Azteca and curanderismo ceremonial community located in central and northern New Mexico, and central México. This project also explored if and how these rituals recognize the practitioners’ indigeneity. As a Mexican American and Native scholar and ceremonial participant of this community, I provided an “insider’s” understanding of the epistemologies and ontologies that inform these ceremonies. My positionality and methodology acted as a lens to critically examine danzantes’ and promotoras tradicionales’ claims of indigeneity. Importantly, this work provides a fluid conceptualization …

The Impact Of Temporal Resolution On Clinical Decision-Making For Individuals With Dysphagia, Shauna Corinne Murray

Speech and Hearing Sciences ETDs

INTRODUCTION: Dysphagia, or a disordered swallow, affects up to 1 in 25 individuals in the United States. The gold standard for assessing dysphagia is the videofluoroscopic evaluation of swallowing (VFES). This allows the clinician to observe the swallow anatomy in motion via an X-ray movie, which historically was recorded at 30 frames per second. In recent years VFES have been performed at less frames per second due to radiation concern. This project investigates the effect of using lower temporal resolutions on assessment of video-fluoroscopic swallow studies.

METHODS: In this investigation, 30 swallow studies, all acquired at 30 frames per second, …

Addressing New Forms Of Racism Part I: Defining Microaggressions, Victoria Peña-Parr

Black History at UNM

Sonia Gipson Rankin, Assistant Professor at The University of New Mexico’s School of Law, defines microagressions, explains how they are normalized in society, and their impact on individuals. This article is the first of two.The second article: Addressing New Forms of Racism Part II: Preventing Microagressions, can be found in the Black Lives Matter Collection. Both articles are a part of the Racism: An Educational Series, produced by the UNM Newsroom.

The Ego At An Impasse: Aesthetic Empathy And The Abject D’Art In Fin De Siècle Supernatural Fiction, Leandra E. Binder

English Language and Literature ETDs

This dissertation examines the symbol of an art object which represents a corpse or dead person’s identity, what I call the abject d’art, as it appears in fin de siècle supernatural fiction by Vernon Lee (Violet Paget) to identify late Victorian notions of Kristevan abjection, avant la lettre. Lee’s aesthetic philosophy informs her use of the abject d’art, especially her examination of the empathetic process as part of aesthetics to explain how individuals represent and respond to objects mentally and emotionally. Through her analysis of empathy, Lee identifies the ego as a fallible moderator of an individual’s …

Musical Wonder And Awe In Narnia: Comparing Two Related Emotions, Laura Steiner

Music ETDs

Wonder and awe are often considered to be synonyms. But though these emotions are similar, a more nuanced look at their musical representations reveals that they are not entirely the same. This thesis examines the difference between musical wonder and awe in music from The Lion, The Witch and the Wardrobe, a 2005 film about siblings who find a magical world in a wardrobe. After a review of the literature on musical wonder, the music from two scenes is analyzed. The wardrobe scene, in which the youngest child discovers the land of Narnia, depicts wonder visually. Certain musical characteristics, both …

Motivation Interviewing: A Tool For Servant Leadership, Jemima Neddy Organ

Organization, Information and Learning Sciences ETDs

ABSTRACT

The purpose of the study was to explore Motivational Interviewing (MI) as a tool that Servant Leaders (SL) could use to enhance their own leadership skills in motivating workers. The participants were seven leaders from VA hospitals in the U.S. who had undergone SL and MI training. Narrative Inquiry based on Polkinghorne (1988, 1995, 2005, 2007) with open, action, emotional, and values coding (Saldaña, 2015) along with structural story coding based on Labov (1972, 1982, 1997) and Patterson (2002) revealed the central theme that MI fostered good relations between leaders and workers in addition to four subthemes that MI …

A Phenomenological Investigation Of The Contextual Variability And Anticipation Of Stuttering, Amanda D. Ortiz-Alvarez

Speech and Hearing Sciences ETDs

Stuttering is a neurologically based speech impairment often defined by listener-oriented parameters (i.e., its overt characteristics). These fail to encompass contextual variability and anticipation, two facets of the speaker’s experience which, though frequently encountered by people who stutter (PWS), remain poorly understood and largely under-researched. To better understand the subjective underpinnings of these phenomena, as well as how PWS conceptualize and relate to their stuttering, the present study sought to explore a) the experiences of PWS with the unpredictable and/or variable nature of their stuttering, as well as their beliefs surrounding potential contributors to its variability; b) the experiences of …

Small Molecule Analog Studies Of Paramagnetic Dmso Reductase Enzyme Family Intermediates, Khadanand Kc

Chemistry and Chemical Biology ETDs

Pyranopterin molybdenum and tungsten enzymes are expressed in numerous organisms from all domains of life. These enzymes catalyze a variety of atom, hydride, and electron transfer reactions. The enzymes are of great importance in the biogeochemical cycles of nitrogen, carbon, and sulfur. In recent years, chemists have investigated applications for some of these enzymes as industrial biocatalysts. The dimethylsulfoxide reductase (DMSOr) enzyme family is the broadest family of pyranopterin Mo enzymes. The first coordination sphere of the Mo or W-containing active site for each member of this family is made up of 4 sulfur donors from the two pyranopterin dithiolenes …

Characterization Of The Overexpression Of The Native H+-Pumping Pyrophosphatase In The Microalga Picochlorum Soloecismus, Kimberly T. Wright

Biology ETDs

Microalgae are of interest for the creation of sustainable and cost competitive alternatives to petroleum-based fuels and chemicals. However, cultivation, extraction and processing of algal biomass requires improved yields to achieve economic feasibility. The advancement of microalgal biotechnology and various genetic engineering techniques allow the improvement of microalgae biomass for this purpose. Here, the characterization of the overexpression of the native vacuolar H+ pumping pyrophosphate (AVP1) in Picochlorum soloecismus was examined. AVP1 overexpression causes biomass increase in relevant plant crops. When overexpressed in this microalga it increases carbon storage in the form of starch in a closed laboratory photobioreactor. However, …

Sex Differences In Age-Related Disease, Matthew Robert Schwartz

Anthropology ETDs

Life history theory posits the evolution of sex-biased traits through asymmetries in the costs of reproduction. The research presented here evaluated the downstream effects of sex-biases in two age-related disease profiles: tooth loss, in which females exhibit a higher disease burden, and melanoma, in which females have a survival advantage.

Among the Tsimane, a natural fertility population of forager-horticulturalists with a high lifetime fertility and no access to oral healthcare, females lose more than males and around half a tooth per child. Parity accounts for 1.2\% of variation in tooth loss within females, but no variation in tooth loss in …

Sexual Dimorphism In Host Innate Response To Staphylococcus Aureus: Mechanisms Driving Sex Differences In Immune Cell Function And Host-Directed Interventions, Srijana Pokhrel

Biomedical Sciences ETDs

With the emerging antibiotic resistance, Staphylococcus aureus, primary causative agent of skin and soft tissue infections (SSTIs) as well as other life-threatening conditions has become a global health concern. While factors contributing to host defense against S. aureus SSTIs has been well studied, impact of sex as a variable has not been reported. In Chapter 2, we uncover the sex-specific differences in host response to S. aureus SSTIs and the contribution of female sex hormone, estrogen (E2) in providing protection in females. In Chapter 3, we identify mechanisms of innate differences in neutrophils bactericidal efficacy between sexes and in …

Fluvial Geomorphic And Hydrologic Evolution And Climate Change Resilience In Young Volcanic Landscapes: Rhyolite Plateau And Lamar Valley, Yellowstone National Park, Benjamin Newell Burnett

Earth and Planetary Sciences ETDs

Quaternary volcanism associated with the last caldera cycle in Yellowstone National Park included emplacement of ash-flow tuffs, massive rhyolite flows ranging from 79 to 484 ka, and valley-filling basalts. This study examines (1) the evolution of spring hydrology with flow age on the Rhyolite Plateau, (2) initial development and evolution of stream networks on the rhyolite flows, and (3) the impact of the 630 ka caldera formation and volcanic flow emplacement on Lamar Valley incision rates.

Integrated stream networks formed within 79 kyr on the Rhyolite Plateau. Incision is focused on steep flow margins and knickpoints and is dependent on …

“Pre-Packaged Sovereignty”: The Fallacy Of Indian Self-Determination In The Bureau Of Indian Affairs (Bia) Tribal Social Services Programs, April Kateri Chavez

American Studies ETDs

This thesis examines the Bureau of Indian Affairs (BIA) tribal social services programs in New Mexico Native reservation communities. I rely on interviews with current/former BIA social workers and administrators to contextualize my analysis, while revealing the limits of existing social work scholarship and offering recommendations for future scholarship and community work. Using critical Indigenous studies and feminisms along with critical social work, I advance two primary arguments. The first is, despite the so-called self-determination era, the Bureau of Indian Affairs (BIA) functions as a settler colonial administration that diminishes tribal sovereignty and perpetuates racist and gendered violence. The capacity …

Fusion Of Elastin Like Polypeptides To Rna Binding Motifs For Programmable Binding Of Nucleic Acids, Dominic Medina

Biomedical Engineering ETDs

Intrinsically disordered proteins (IDPs) with RNA binding capability have recently been found to play important roles in several cellular processes, including the formation of phase separated membraneless organelles to regulate gene expression. An important class of membraneless organelles is stress granules, which enable cells to survive periods of environmental stress by regulating gene expression in the cytoplasm. Cells use a variety of ribonucleoprotein granules, primarily comprised of RNA and chaperone protein components, and can regulate cellular metabolism by sequestering and processing regulatory components, such as messenger RNAs, within these phases separated ‘organelles’. To recapitulate this cellular behavior, the genetically engineered …

Post-Wildfire Geomorphic Stream Response In Six New Mexican Watersheds, Aljaz Praznik

Civil Engineering ETDs

Wildfire causes severe physical changes to watersheds, which then leads to geomorphic changes in the burned watersheds. In New Mexico and the southwestern U.S., flooding is a common response after a wildfire, due to higher water runoff from the hillslopes and sediment erosion rates. These flood events change the erosion and deposition characteristics of a stream, which can result in the deposition of a large amount of sediment near the communities living downstream. The objective of this research was to analyze and compare post-fire geomorphic stream response caused by six different wildfires in New Mexico with the goal to create …

Advanced Parallel Algorithms In Computational Electromagnetics, Shu Wang

Electrical and Computer Engineering ETDs

The rapid development of high performance computing has pushed the computational electromagnetic(CEM) towards high accuracy, high fidelity and extreme computational scales. There is a great need for existing CEM solvers to have enhanced parallelism and scaling capability. The purpose of this dissertation is to investigate advanced parallel algorithms for both frequency and time domain solvers.

In frequency domain, this work first develop the underpinnings of parallel preconditioning technique and high-order transmission condition in the context of multi-solver scheme. The result is a computing resource-aware and implementation wise compact solver. Then this work targeted at developing efficient algorithms for cases where …

Device-Level Predictive Modeling Of Extreme Electromagnetic Interference, Nishchay H. Sule

Electrical and Computer Engineering ETDs

Radio Frequency (RF) interference is a prominent issue for modern electronic devices. As device size and supply power shrink to meet the on-going demand for compact and complex Integrated Circuits (ICs), their susceptibility to external noise coupling to the input or power supply increases significantly. One such type of noise that acts upon a system to be considered is Extreme Electromagnetic Interference (EEMI). Previous works done to understand and evaluate the impact of EEMI onto a system or sub-system have been conducted on a statistical or empirical analysis level, which has led to complex and convoluted analysis, that requires significant …

Software Execution Under Extreme Electromagnetic Interference, Luis Ariel Valbuena Reyes

Electrical and Computer Engineering ETDs

Software routines that deviate from the original algorithm’s goal due to a perturba- tion agent is a phenomenon that has been observed for a long time now. From unin- tended executions on flight control computers during the dawn of space exploration, passing through hardware Trojans tampering in corporate security, to sensitive med- ical equipment compromised to the point of changing the amount of delivered drug, the time intervals, and the reported biomedical measured data, such intrusions are a major risk challenging society. In this dissertation, a computer under perturbation is modeled by a hybrid sys- tem that captures the digital …

Early Time (E1) High Altitude Electromagnetic Pulse Effects On Lightning Surge Arresters And Trip Coils, David Erney Sanabria

Electrical and Computer Engineering ETDs

A High Altitude Electromagnetic Pulse (HEMP) is a potential threat to the power grid. HEMP can couple on transmission lines causing large overvoltages, which could be harmful to the line and everything else connected to it. The effects of overvoltages on all sorts of devices in the power grid need to be understood. The work developed here is a joint effort between The University of New Mexico and Sandia National Laboratories; The devices that are within the scope of this effort are Trip Coils and Lightning Surge Arresters (LSA). Existing data on HEMP, existing standards, and a previous analysis, were …

Photo-Characterization Of Selective Luminescent Protein Aggregate Sensors - Oligo-P-Phenylene Ethynylene (Opes), Florencia A. Monge

Biomedical Engineering ETDs

Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease,

and related tauopathies, are a global health care challenge due to the lack of early

treatment and diagnostic options. These diseases take an emotional and physical

toll on patients, caretakers, and a rather large economic toll on taxpayer-based

health care systems. The pathologies of these diseases are characterized by the

aggregation of misfolded proteins, amyloid-β (Aβ) and tau, into β-sheet rich

structures called amyloids. Research has found that the presence of protein

aggregates predates cognitive symptoms by years. Current diagnostic tools are

based on the detection of these amyloid aggregates, historically by …

Reflections On Learning, Communication, And Identity In A Hybrid Course On Language Development, Anni Leming

Language, Literacy, and Sociocultural Studies ETDs

This research explored the relationship between the face-to-face and online spaces in my university hybrid course on first and second language development in cultural contexts, as well as my students’ and my own communication, learning, and development of identity as teachers and students. This study was grounded in practitioner inquiry and ethnography of communication as a methodological tool to understand the role of language among teacher and students in the virtual co-construction of knowledge. The findings suggest that self-disclosures, legitimizing the self and others, and relatability played key roles in students navigating new course content, a hybrid space and discussions …

Spatial Analysis Of Bias Corrected Rainfall Data Sets Within Albuquerque, New Mexico Metropolitan Area, Cassy Scarlott- Mcclintock

Civil Engineering ETDs

The Next Generation Radar (NEXRAD) was implemented as one of the first network-wide operational radar- estimated precipitation products in the United States in 1988. The algorithms within this system bring drastic advancements to operational flood forecasting when compared to prior radars and even rain gage systems. The objectives were; (1) to determine how radar plays a role in estimating precipitation by comparing rainfall accuracy to other sources such as calibrated radar data and gage data within Albuquerque, New Mexico and (2) to determine if distance from the radar affects estimation of rainfall. The sets of data compared were from: (1) …

Suicide, Heroin Use And Protective Resiliency Factors Amongst Transgender Adolescents In New Mexico, Richard Gadomski

Biomedical Sciences ETDs

Transgender people experience significant mental health inequities. The goal of this study was to evaluate disparities related to suicide attempt in the past 12 months and ever heroin use in cisgender versus transgender adolescents, and identify specific resiliency factors associated with a decrease in the prevalence of suicide attempt and heroin use in transgender adolescents. This study is a cross-sectional, secondary analysis of the 2017 New Mexico Youth Risk and Resiliency Survey among high school students. The odds of suicide attempt were 5.5-fold greater, and the odds of lifetime heroin use were nearly 14-fold greater, for transgender compared to cisgender …