Perinatal Exercise Effectiveness To Prevent Offspring High-Altitude Pulmonary Hypertension, Eric Leslie

Health, Exercise, and Sports Sciences ETDs

The effectiveness of perinatal exercise (i.e., exercise by mothers immediately prior to, throughout, and after pregnancy) to attenuate high-altitude pulmonary hypertension and associated health consequences in the offspring exposed to chronic hypoxia in early life was investigated. Four groups were used to compare the effects of perinatal exercise to offspring exposed to low altitude (i.e., normoxic) conditions or simulated 4500 meters of high altitude (i.e., hypoxic) as well as their respective, sedentary controls. Offspring in the hypoxic groups had lower body weights and tail lengths as well as higher hematocrits, right ventricular systolic pressures, and right heart weights. The hypoxic …

Reinforcement Learning-Based Demand Response Management In Smart Grid Systems With Prosumers, Jenilee Jao

Electrical and Computer Engineering ETDs

In this thesis, we introduce a reinforcement learning-based price-driven Demand Response Management (DRM) mechanism in smart grid systems consisting of prosumers. Our proposed approach accounts for the prosumers behavioral characteristics and models the emerging interactions among all the involved actors in the smart grid system, i.e., prosumers, Energy Management System (EMS) and utility companies. In particular, an off-policy reinforcement learning is introduced enabling the EMS to determine the optimal price that should be announced to the prosumers on an hourly-basis towards minimizing the overall systems cost. In this process, the utility companies hourly-based wholesale price and the prosumers energy generation …

Inhibition Of Rad18 By Arsenic, Lindsay B. Volk

Biomedical Sciences ETDs

Arsenite exposure leads to the retention of UV-induced DNA damage, thus burdening translesion synthesis (TLS). Rad18 is an essential factor in initiating TLS through PCNA monoubiquitination and is implicated in homologous recombination. It contains two functionally and structurally distinct zinc fingers that are potential targets for arsenite binding. Results from this study reveal arsenite binding to both zinc fingers of Rad18 and a corresponding loss of domain function. Importantly, arsenite inhibited Rad18 RING-dependent PCNA monoubiquitination and polymerase eta recruitment to DNA damage. Further analysis demonstrated multiple effects of arsenite, including the reduction in the nuclear localization and UV-induced chromatin recruitment …

Lens: A Novel Image Processing-Based Approach For Low-Cost Segmentation Of Computed Tomography Scans Of Lungs, Monica Hinga

Computer Science ETDs

A staggering amount of data has been collected and analyzed since the beginning of the COVID-19 pandemic. Some of that data, however, particularly computed tomography (CT) scans of lungs, are difficult to analyze computationally. Segmentation of COVID-19 lesions provides researchers with insights into where lesions form, their volume, and in the case of time course data, how lesions grow as disease progresses. Spatial information, which has received little attention in the literature, has the potential to provide valuable insight to within-host viral and immune dynamics. Unfortunately, state-of-the-art supervised deep learning methods require labeled data, which can be prohibitively expensive to …

Void-Semiconductor Gaas Photonic Crystal Surface-Emitting Lasers By Epitaxial Regrowth And Single-Epitaxy Methods, Kevin James Reilly

Nanoscience and Microsystems ETDs

Monolithic semiconductor lasers including edge-emitting lasers (EELs) and vertical-cavity surface-emitting lasers (VCSELs) fail to realize simultaneous achievement of both high-power high-quality beams due to intrinsic limitations of their resonant cavity. Photonic crystal surface emitting lasers (PCSELs) address these structural limitations through employment of a two-dimensional photonic crystal (PC) cavity that creates feedback at a single wavelength for laterally scalable devices. This function of the PC allows PCSELs to power scale with area while maintaining single-mode emission required for diffraction-limited beams. In this way, PCSELs fulfill an industry demand for high-power high-quality lasing from a single chip.

Early PCSELs were fabricated …

On The Effects Of Geometrical And Fluid Conditions On Thermal-Hydraulics Of Miniature Heat Sinks, Mahyar Pourghasemi

Mechanical Engineering ETDs

During the past three years, miniature heat sinks have been integrated into the cooling loop of devices such as MW-class gyrotron resonators and high-power laser arrays. These applications involve high cooling rates in the range of 20-25 MW/m². Liquid metals such as Na and NaK offer very high thermal conductivity in the range of 16-79 W/mK, while their dynamic viscosities are only slightly higher than water viscosity. They can also be used in applications with operating temperatures varying from 25 ^oC to as high as 800 ^oC due to their very high boiling points. Several research …

Cyber-Secure Distributed Control Of Microgrids With Improved Communication And Control Protocols, Jee Won Choi

Mechanical Engineering ETDs

This dissertation proposes a cyber-secure distributed control of microgrids with improved communication and control protocols. The finite-time event-triggered control protocol for islanded AC and DC secondary control is introduced. For AC microgrids, the proposed strategy can effectively perform frequency restoration and voltage regulations while sharing the active and reactive power among the distributed generators (DGs) based on their power ratings. For DC microgrids, the proposed control protocol can provide accurate current sharing and critical bus voltage regulation. The finite-time control enables a system to reach a consensus in a finite period of time enhanced from asymptotic convergence. The event-triggered communication …

Spatial Single-Cell Identification Of Cell Layers Within Mouse Brain Using A Novel Spatially Resolved Transcriptomics Technology, Radha Swaminathan

Biomedical Engineering ETDs

Spatially resolved transcriptomics technologies investigate gene expression in the context of a tissue. While imaging-based technologies enable gene expression quantification at a single-cell level, only two NGS-based technologies are currently capable of single-cell resolution. Both Stereo-seq and Seq-Scope involve two rounds of sequencing: one to sequence the location of spatial barcodes and the other to obtain sequence of cDNA. Thus, the objective of the research study is to develop a technology that can capture transcripts from every cell of a tissue without the need for two rounds of sequencing. To this end, a capture surface or barcoded array (similar to …

Racial And Ethnic Differences In The Receipt Of Metabolic Syndrome Risk Factor Screening And Treatment Among Prostate Cancer Patients Treated With Androgen Deprivation Therapy., Yazan K. Barqawi

Pharmaceutical Sciences ETDs

Background: Racial and ethnic health disparities in prostate cancer prevalence, incidence, mortality, quality of life, screening, and treatment constitute the largest of all cancer disparities. These health disparities are associated with higher morbidity and mortality rates in minority populations. Treatment with androgen deprivation therapy (ADT) has been the most widely used therapeutic modality to reduce the progression of prostate cancer to a worse disease stage and relieve potential obstructive symptoms. However, ADT is associated with possible toxic metabolic and cardiovascular (CVS) adverse events that may occur within six months of ADT initiation. These adverse events include metabolic syndrome, type II …

Mitigation Impact Of Statewide Non-Pharmaceutical Policies On Covid-19: An Application Of Infectious Disease Transmission Model And Partially Observed Markov Process To New Mexico, Xingya Ma

Mathematics & Statistics ETDs

This thesis is an application of epidemiological models for infectious disease transmission and the use of partially observed Markov process (POMP) for model fitting. It focuses on COVID-19 pandemic in the state of New Mexico. The analysis covered March 2020 to June 2021. Daily data of COVID19 cases and deaths and a daily index of eleven statewide government non-pharmaceutical intervention (NPI) policies were collected from six public sources and were validated. These data were integrated through the Susceptible-Exposed-Infected-Removed (SEIR) model. Estimated daily transmission rates between the model compartments quantify the impact of the mitigation policies, and show that transmission rates …

Interdisciplinary Integrative Oncology, Naomi L. Valles

InterProfessional Education Research and Scholarship

No abstract provided.

Efl Teachers’ Understandings Of The Role Of Assessment In Second Language Learning, Evelyn Almeida

Language, Literacy, and Sociocultural Studies ETDs

Given the important role of assessment in the process of Second Language Learning (SLL) and framed within Vygotsky’s Zone of Proximal Development (ZPD), this study aims to analyze: (1) how EFL teachers’ understanding of the role of assessment in SLL can be improved, (2) how effective dynamic assessment is in their teaching practices, (3) how EFL teachers’ assessment practices reflect their understanding of the concept of assessment/dynamic assessment, and (4) what strategies can help them understand these concepts. These four points are studied within the context of English classes at a Language Institute in Quito, Ecuador. This project’s contribution brings …

Estimating Vehicle Infrastructure: Downtown Albuquerque, New Mexico, Zachery Phillip Baiamonte

Architecture and Planning ETDs

Cities have little knowledge about their parking infrastructure despite clear evidence that abundant parking has environmental, economic, and transportation consequences. The objective of this thesis is to illustrate the need to accurately estimate the area dedicated to vehicle infrastructure (parking lots and streets) within urban areas. I focused on a method that estimated the vehicle infrastructure area within the Downtown Core of Albuquerque, New Mexico, by cross-referencing geospatial cadastral data with minimum parking requirements. Three parking space types were identified: 1) parking in structures; 2) surface parking (parking lots and residential driveways); and 3) on-street parking. To illustrate the need …

Traumatic Brain Injury And Psychopathy In Incarcerated Men And Women, Tessa Cappelle

Psychology ETDs

Traumatic brain injury (TBI) is one of the most suffered injuries with detrimental effects on the individual’s health, personality, and behavior. Overlap exists between TBI sequelae and symptoms of psychopathy. Both conditions are especially prevalent in incarcerated populations which makes studying their interrelation critical. Two studies examined the relationship between history of TBI (TBI+ vs. TBI-) and psychopathy (via the Hare Psychopathy Checklist-Revised; PCL-R) in adult incarcerated men and women at correctional facilities in New Mexico and Wisconsin. Study 1 included 342 women, study 2 included 1049 men. Measurement invariance was evident for TBI+ and TBI- for both studies. TBI+ …

Exploring The Role Of Dieting Style In Nutritional And Psychological Health Among College Women, Hayley L. Vanderjagt

Psychology ETDs

The current study aimed to profile styles of eating among dieting and non-dieting college-aged women, and to explore the extent to which dieting attitudes were associated with both nutritionally healthy eating and psychological well-being. A latent profile analysis was conducted using indicators of self-reported intuitive eating, binge eating, and two psychometric measures of dietary restraint; various measures of eating restraint were utilized to potentially capture distinct characteristics of dieting, such as self-discipline and disinhibition (Polivy et al., 2020; Stice et al., 2010). Four distinct probabilistic profiles emerged, indicating that individuals within the study population could be meaningfully categorized as Intuitive …

A Phenomenological Study Of Collegiate Recovery Leadership, Marni Goldberg

Teacher Education, Educational Leadership & Policy ETDs

Due to the marginalized status of the population they serve, collegiate recovery programs are generally underfunded and employ one staff member who typically holds other job tasks in addition to those of collegiate recovery leader. The consequence of the varied nature by which collegiate recovery programs are founded and implemented is inconsistency, which can threaten the longevity of the field. The purpose of this phenomenological study was to elicit information directly from collegiate recovery leaders to gain a deeper understanding of their lived experience, in order to determine how to best serve and support higher education students in recovery from …

Fabrication, Characterization, And Simulation Of Graphene-Copper Electrical Conductors, Raju Prasad Ghimire

Nanoscience and Microsystems ETDs

The addition of nanocarbons to copper (Cu), specifically in the form of graphene (GN), has been shown to enhance copper's properties. GN-Cu nanocomposites can potentially achieve higher electrical, mechanical, and thermal properties compared with copper. These characteristics make GN-Cu materials interesting for several applications including but not limited to interconnects, high voltage lines, and rotating machines. Copper’s microstructure and nanoscale interfacial phenomena between the GN and Cu control charge conduction in GN-Cu materials. In this work, we investigated the possibilities of conductivity enhancement in multi-layered GN-Cu composites both theoretically (classical, quantum, and atomistic models) and experimentally.

Additionally, our work elucidates …

How South Asian Activists Queer The Model Minority Myth: A Critical Oral History Project, Noorie Baig

Communication ETDs

The model minority myth (MMM) is predicated on stereotypical perceptions of Asian Americans as subservient high-achievers who comply with the ideologies of meritocracy, whiteness, and capitalism. However, South Asian American (SAA) activists and community organisers, the focus of this study, are working to confront and abolish racist, heterosexist, and other exclusionary injustices, policies, and practices. This dissertation seeks to understand the historical influences of the MMM, the challenges SAA activists and organisers face, and the communication strategies they use to negotiate the MMM through their activism. Oral history methods and critical thematic analysis are used to elicit and analyse personal …

Assessing Knowledge And Perceptions About Cancer Among American Indians Of The Zuni Pueblo, Nm, Safia Safi, Donica Ghahate, Jeanette Bobelu, Andrew L. Sussman, Joseph Rodman, Angela Wandinger-Ness, Shiraz I. Mishra, Thomas Faber, Cheryl Willman, Vallabh Shah

Pathology Research and Scholarship

American Indians (AIs) in New Mexico have lower cancer screening rates compared to other populations and are more likely to be diagnosed with cancer at an advanced stage of the disease as reported by Li et al. (Archives of Internal Medicine 163(1):49-56, 2003). AIs also have the lowest 5-year cancer survival rates compared to any ethnic/racial group in the USA as reported by Clegg et al. (Arch Intern Med 162:1985-1993, 2002) and Edwards et al. (Cancer 97:1407-1427, 2005). Numerous barriers such as cultural beliefs, fear, fatalism, mistrust, stigma, and lack of culturally appropriate interventions could contribute to low cancer screening …

Investigation Of Gaas Double Heterostructures For Photonic Heat Engines, Nathan Giannini-Hutchin

Optical Science and Engineering ETDs

The creation of a laser cooled semiconductor device has been a long sought achievement. GaAs-based devices have emerged as a promising candidate for the realization of this goal. Efforts to improve the efficiency of such devices have enabled the material to exhibit external quantum efficiencies (EQE, a measure of the probability that an excitation leads to the emission of a photon) of 99.5\%. Despite this impressive feat, a laser coolable device remains elusive.

To investigate the obstacles to such a device, the material characteristics of GaAs-based double heterostructures (DHS) are theoretically and experimentally examined. Through this study, a GaAs $\vert$ …

Visionary Women Or Suspected Witches: The Shifting Use And Construction Of Reputation In Accusations Of Witchcraft During The High And Late Middle Ages, Megan E. Hattey

History ETDs

Throughout the high and late Middle Ages, an individual’s social acceptance and well-being were heavily dependent upon fama, or reputation, they cultivated within their communities. Women, especially, constructed and molded their reputations to protect themselves from hardship and social ostracization, allowing them a degree of agency in social situations. In this thesis, I argue that the mindful development of one’s fama was key for women to protect themselves from accusations of witchcraft. Through the lives of Hildegard of Bingen, Elisabeth of Schönau, and Jeanne d’Arc, I demonstrate how medieval reputations were built, the trifold nature it could hold, and …

Effects Of Home-Based High-Intensity Interval Training Versus Continuous Walking On Cognition In Overweight And Obese Women, Kelsey C. Bourbeau

Health, Exercise, and Sports Sciences ETDs

Objective: The purpose of the present study was to determine whether six weeks of home-based high-intensity interval training versus six weeks of moderate-intensity walking improves cognition, depression, and anxiety in women that are overweight or obese. Design: A randomized control trial design. Subjects: Twelve sedentary women characterized as overweight or obese were randomized into either a six-week home-based high-intensity interval training (HIIT, n = 6, 26.6 ± 8.9 years, 37.4 ± 4.9% body fat) group or a six-week moderate-intensity walking (Walk, n = 6, 22.5 ± 3.7 years, 40.2 ± 4.1% body fat) group. Main Measures: Pre- and post-intervention, participants …

Writer Identity Construction Of Thai Efl Students: A Phenomenological Study, Kittika Limpariwatthana

Language, Literacy, and Sociocultural Studies ETDs

ABSTRACT

This empirical study uncovered Thai English as a Foreign Language (EFL) writer identity construction and revealed how Thai culture plays a role in the development using a sociocultural perspective. Data collection for analysis includes interviews with nine Thai college students, a group interview, English writing essays, and artifacts they provided throughout a 15-week English writing course. The focus of this study was to gain insight into the phenomenon of identity construction among EFL writers from perceptions of their lived experiences.

Based on the description of identity development, the research findings focus on two different ways the participants perceived their …

Would You Make It To The Future? Teaching Race In An Assisted Reproductive Technologies And The Law Classroom, Sonia Gipson Rankin

Faculty Scholarship

Would you make it to the future? For the last five years, I have started my Assisted Reproductive Technology (ART) lecture in Family Law with this question. Students take the query seriously. They ponder their lived experiences such as home training, medical history, education, financial well-being, personality traits, work ethic, and social graces when determining if they would be the “model DNA” someone might select in a future society. The good-natured jokes about being nearsighted, having a pitiful jump shot, and wearing orthodontic headgear turn reflective when someone raises the question: would someone in the future select my race? In …

Neutrosophic Analysis Of Risk Factors In The Etiology Of Cerebral Palsy, Piedad Elizabeth Acurio Padilla, Andrés Eduardo Gallegos Cobo, Blanca Cristina Estrella López

Neutrosophic Sets and Systems

No abstract provided.

Characterization Of Materials Properties In Additively Manufactured Aisi-420 Martensitic Steel Deposited By Laser Engineered Net Shaping, Md Mehadi Hassan

Nanoscience and Microsystems ETDs

Metal additive manufacturing (AM) is a disruptive technology enabling the fabrication of complex and near-net-shaped parts by adding material layer-wise. It offers reduced lead production time. AM processes are finding applications in many industrial sectors such as aerospace, automotive, biomedical, and mold tooling. Despite the tremendous advantages of AM, some challenges still prevent this technology's adoption in high-standard applications. Anisotropy and inhomogeneity in the mechanical properties of the as-built parts and the existence of pores and lack-of-fusion defects are considered the main issues in directed energy deposition (L-DED) parts. Laser-engineered net shaping LENS® offers excellent possibilities to fabricate metal tools …

Defining The Role Of Core Histones In Cellular Quiescence, Eric M. Small

Biomedical Sciences ETDs

Quiescence is a distinct cell cycle phase, termed G0, in which growth, transcriptional and translational activity, and replication are halted. Importantly, quiescent cells are viable and can return to the cell cycle. Quiescence is a feature of all organisms and a key hallmark of stem cells; however, the regulation of quiescence is still poorly understood.

Prior studies have implicated chromatin in the regulation of quiescence. In aim 1 I conducted a comprehensive screen of H3 and H4 histone mutants to identify chromatin features that may affect quiescence. I identified several histone residues implicated in transcriptional regulation that altered quiescence and …

Social Presence As A Predictor Of Social Construction Of Knowledge In Discussion Forums In Asynchronous Online Higher Education Courses, Austin Megli

Organization, Information and Learning Sciences ETDs

The three research papers completed and compiled to make up this dissertation explore the relationship between social presence and social construction of knowledge in asynchronous online discussion forums in higher education courses in the instructional technology field. Paper 1 is a literature review of the interaction analysis model (IAM) (Gunawardena et al., 1997) as a methodology, which is used to measure and determine the social construction of knowledge in online discussion forums. This literature review identified and highlighted the need to determine how the social environment of online learning influences the social construction of knowledge. This led to the second …

Single-Crystal Elasticity Of Earth’S Mantle Transition Zone Minerals And High Pressure-Temperature Phase Equilibrium Experiments On Martian Basalts, Wenyi Zhou

Earth and Planetary Sciences ETDs

Wadsleyite and ringwoodite are major minerals in the Earth’s Mantle Transition Zone. Global and local seismic studies have detected strong lateral variations in seismic velocity and anisotropy in the Mantle Transition Zone, reflecting temperature and possible composition variations. Interpretation of these seismic observations requires knowledge of thermoelastic properties of wadsleyite and ringwoodite with different compositions (water and Fe contents) under high pressure-temperature conditions. In this dissertation, we have measured single-crystal elastic properties of wadsleyite and ringwoodite under high pressure-temperature conditions by Brillouin spectroscopy. Based on our measurements and previous experimental results, we further model the effects of water and Fe …

Theoretical Studies Of Molecule-Surface Interactions And Dynamics, Yingqi Wang

Chemistry and Chemical Biology ETDs

Gas-surface scattering involves the conversion of energy in different forms in the impinging molecule, possible bond breaking and forming, and the energy transfer across gas-solid interface. Possible energy dissipation channels include adiabatic energy transfer to the motion of surface phonons and non-adiabatic interactions with surface electron-hole pairs. A complete understanding of the interplay of energy dissipation and physical/chemical changes in the molecule is vital for many important applications such as materials fabrication and heterogenous catalysis.

Gas-surface encounters may occur where non-adiabatic effects are negligible. Two such systems were investigated, both with ample experimental data. One is concerned with the scattering …