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Religious Studies 2022 Apr Self-Study & Documents, Unm

UNM Academic Program Review

UNM Religious Studies APR self-study report, review team report, response to review report, and initial action plan for Fall 2022, fulfilling requirements of the Higher Learning Commission.

Plasma Exchange In The Intensive Care Unit: A Narrative Review, Phillippe R. Bauer, Marlies Ostermann, Lene Russell, Chiara Robba, Sascha David, Bruno Ferreyro, Joan Cid, Pedro Castro, Nicole P. Juffermans, Luca Montini, Tasneem Pirani, Andry Van De Louw, Nathan Nielsen, Julia Wendon, Anne C. Brignier, Miet Schetz, Jan T. Kielsetin, Jeffrey L. Winters, Elie Azoulay, Nine-I Investigators

Pathology Research and Scholarship

In this narrative review, we discuss the relevant issues of therapeutic plasma exchange (TPE) in critically ill patients. For many conditions, the optimal indication, device type, frequency, duration, type of replacement fluid and criteria for stopping TPE are uncertain. TPE is a potentially lifesaving but also invasive procedure with risk of adverse events and complications and requires close monitoring by experienced teams. In the intensive care unit (ICU), the indications for TPE can be divided into (1) absolute, well-established, and evidence-based, for which TPE is recognized as first-line therapy, (2) relative, for which TPE is a recognized second-line treatment (alone …

New Mexico Health Care Workforce Committee 2022 Annual Report, University Of New Mexico - Health Sciences Center

New Mexico Health Care Workforce Committee (2013-ongoing)

No abstract provided.

Percentage Of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy Vs Placebo In The Treatment Of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial, Michael P. Bogenschutz, Stephen Ross, Snehal Bhatt, Tara Baron, Alyssa A. Forcehimes, Eugene Laska, Sarah E. Mennenga, Kelley O'Donnell, Lindsey T. Owens, Samantha Podrebarac, John Rotrosen, J Scott Tonigan, Lindsay Worth

Family and Community Medicine Research and Scholarship

IMPORTANCE: Although classic psychedelic medications have shown promise in the treatment of alcohol use disorder (AUD), the efficacy of psilocybin remains unknown.

OBJECTIVE: To evaluate whether 2 administrations of high-dose psilocybin improve the percentage of heavy drinking days in patients with AUD undergoing psychotherapy relative to outcomes observed with active placebo medication and psychotherapy.

DESIGN, SETTING, AND PARTICIPANTS: In this double-blind randomized clinical trial, participants were offered 12 weeks of manualized psychotherapy and were randomly assigned to receive psilocybin vs diphenhydramine during 2 day-long medication sessions at weeks 4 and 8. Outcomes were assessed over the 32-week double-blind period following …

Analysis Of College Of American Pathologists Von Willebrand Factor Proficiency Testing Program, Eric Salazar, Thomas A. Long, Kristi Johnson Smock, Geoffrey D. Wool, Marian Rollins-Raval, Dong Chen, Neil Selwyn Harris, Clarence W. Chan, John D. Olson, Huy P. Pham, Jacob Ritter, David Unold, Amanda Matzke Vansandt, Andrew Jackson Goodwin Iv

Pathology Research and Scholarship

Von Willebrand factor (VWF) level and/or function is altered in von Willebrand disease (VWD), the most common heritable bleeding disorder worldwide. Laboratory assessment of VWF is continually evolving. Historically, the primary method for the assessment of VWF platelet-binding activity was the ristocetin cofactor assay (VWF:RCo). Contemporary alternative measures of VWF platelet-binding activity include VWF:GPIbR (recombinant; using ristocetin), VWF:GPIbM (recombinant; gain-of-function mutant), and monoclonal antibody. Recently, the American Society of Hematology, International Society on Thrombosis and Haemostasis, National Hemophilia Foundation, and World Federation of Hemophilia collaboration issued guidelines recommending the use of newer assays of VWF platelet-binding activity (VWF: GPIbM, VWF: …

Docking Of Syk To Fcεri Is Enhanced By Lyn But Limited In Duration By Ship1, William K. Kanagy, Cédric Cleyrat, Mohamadreza Fazel, Shayna R. Lucero, Marcel P. Bruchez, Keith A. Lidke, Bridget S. Wilson, Diane S. Lidke

Pathology Research and Scholarship

The high-affinity immunoglobulin E (IgE) receptor, FcεRI, is the primary immune receptor found on mast cells and basophils. Signal initiation is classically attributed to phosphorylation of FcεRI β- and γ-subunits by the Src family kinase (SFK) Lyn, followed by the recruitment and activation of the tyrosine kinase Syk. FcεRI signaling is tuned by the balance between Syk-driven positive signaling and the engagement of inhibitory molecules, including SHIP1. Here, we investigate the mechanistic contributions of Lyn, Syk, and SHIP1 to the formation of the FcεRI signalosome. Using Lyn-deficient RBL-2H3 mast cells, we found that another SFK can weakly monophosphorylate the γ-subunit, …

Clinical Practice Guidelines From The Association For The Advancement Of Blood And Biotherapies (Aabb): Covid-19 Convalescent Plasma, Lise J. Estcourt, Claudia S. Cohn, Monica B. Pagano, Claire Iannizzi, Nina Kreuzberger, Nicole Skoetz, Elizabeth S. Allen, Evan M. Bloch, Gregory Beaudoin, Arturo Casadevall, Dana V. Devine, Farid Foroutan, Thomas J. Gniadek, Ruchika Goel, Jed Gorlin, Brenda J. Grossman, Michael J. Joyner, Ryan A. Metcalf, Jay S. Raval, Todd W. Rice, Ralph R. Vassallo, Jeffrey L. Winters, Aaron A R Tobian, Beth H. Shaz

Pathology Research and Scholarship

DESCRIPTION: Coronavirus disease 2019 convalescent plasma (CCP) has emerged as a potential treatment of COVID-19. However, meta-analysis data and recommendations are limited. The Association for the Advancement of Blood and Biotherapies (AABB) developed clinical practice guidelines for the appropriate use of CCP.

METHODS: These guidelines are based on 2 living systematic reviews of randomized controlled trials (RCTs) evaluating CCP from 1 January 2019 to 26 January 2022. There were 33 RCTs assessing 21 916 participants. The results were summarized using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) method. An expert panel reviewed the data using the GRADE framework …

The Validity Of Mcat Scores In Predicting Students' Performance And Progress In Medical School: Results From A Multisite Study, Joshua T. Hanson, Kevin Busche, Martha L. Elks, Loretta E. Jackson-Williams, Robert A. Liotta, Chad Miller, Cindy A. Morris, Barton Thiessen, Kun Yuan

Pathology Research and Scholarship

PURPOSE: This is the first multisite investigation of the validity of scores from the current version of the Medical College Admission Test (MCAT) in clerkship and licensure contexts. It examined the predictive validity of MCAT scores and undergraduate grade point averages (UGPAs) for performance in preclerkship and clerkship courses and on the United States Medical Licensing Examination Step 1 and Step 2 Clinical Knowledge examinations. It also studied students' progress in medical school.

METHOD: Researchers examined data from 17 U.S. and Canadian MD-granting medical schools for 2016 and 2017 entrants who volunteered for the research and applied with scores from …

The Genomic Landscape Of Pediatric Acute Lymphoblastic Leukemia, Samuel W. Brady, Kathryn G. Roberts, Zhaohui Gu, Lei Shi, Stanley Pounds, Deqing Pei, Cheng Cheng, Yunfeng Dai, Meenakshi Devidas, Chunxu Qu, Ashley N. Hill, Debbie Payne-Turner, Xiaotu Ma, Ilaria Iacobucci, Pradyuamna Baviskar, Lei Wei, Sasi Arunachalam, Kohei Hagiwara, Yanling Liu, Diane A Flasch, Yu Liu, Matthew Parker, Xiaolong Chen, Abdelrahman H. Elsayed, Omkar Pathak, Yongjin Li, Yiping Fan, J Robert Michael, Michael Rusch, Mark R. Wilkinson, Scott Foy, Dale J. Hedges, Scott Newman, Xin Zhou, Jian Wang, Colleen Reilly, Edgar Sioson, Stephen V. Rice, Victor Pastor Loyola, Gang Wu, Evadnie Rampersaud, Shalini C. Reshmi, Julie Gastier-Foster, Jaime M. Guidry Auvil, Patee Gesuwan, Malcolm A. Smith, Naomi Winick, Andrew J. Carroll, Nyla A. Heerema, Richard C. Harvey, Cheryl L. Willman, Eric Larsen, Elizabeth A. Raetz, Michael J. Borowitz, Brent L. Wood, William L. Carroll, Patrick A. Zweidler-Mckay, Karen R. Rabin, Leonard A. Mattano, Kelly W. Maloney, Stuart S. Winter, Michael J. Burke, Wanda Salzer, Kimberly P. Dunsmore, Anne L. Angiolillo, Kristine R. Crews, James R. Downing, Sima Jeha, Ching-Hon Pui, William E. Evans, Jun Yang, Mary V. Relling, Daniela S. Gerhard, Mignon L. Loh, Stephen P. Hunger, Jinghui Zhang, Charles G. Mullighan

Pathology Research and Scholarship

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL, we find that, despite a generally low mutation burden, ALL cases harbor a median of four putative somatic driver alterations per sample, with 376 putative driver genes identified varying in prevalence across ALL subtypes. Most samples harbor at least one rare gene alteration, including 70 putative cancer driver genes associated with ubiquitination, SUMOylation, noncoding transcripts and other functions. In hyperdiploid B-ALL, chromosomal gains are acquired early and synchronously before ultraviolet-induced mutation. By contrast, ultraviolet-induced mutations precede chromosomal …

Distance Estimates To Evolved Stars Using Infrared Emission And Verification And Validation Of The Plasma Code Empire, Brandon M. Medina

Physics & Astronomy ETDs

Gaining insight into the structure and dynamics of the Milky Way is important for understanding the universe on a large scale. Evolved stars on the Asymptotic Giant Branch are useful for studying the Milky Way because their emission is peaked in the infrared, where interstellar extinction effects are not as dominant. To further understand the physical properties of these objects like luminosity and investigate the Galaxy's structure, we need distance estimates. Obtaining distance estimates for these evolved stars via trigonometric parallax measurements is time-consuming, so infrared surveys studying Asymptotic Giant Branch stars can benefit from other distance estimate methods. In …

Measuring The Success Of A Project Echo Implementation: Results From An International E‑Delphi Study, Perrin Moss, Nicole Hartley, Dana Newcomb, Trevor Russell

Project ECHO Bibliography

There is an increasing global need for organisations to utilise high-quality telementoring models to support workforce development and mentorship. Project ECHO is a validated telementoring model that has been adopted by over 700 organisations globally across multiple sectors. To date there is no consolidated list of success indicators by which organisational teams can assess or benchmark their implementation of Project ECHO across sectors. An e-Delphi methodology was adopted to facilitate a comprehensive means of identifying indicators that could be used to assess the implementations of Project ECHO globally. This paper presents a consolidated framework of indicators that support teams to …

Improving Accuracy Of Total Hip Arthroplasty Templating Considering Difffferences In Magnifification Of Preoperative X-Rays, Ryan J. Lubbe, Robert Mercer, Apostolos Dimitroulias, Benjamin J. Hansen

Western Journal of Orthopaedics

Background: The authors present a novel technical strategy in preoperative planning for templating total hip arthroplasty (THA), which involves the intraoperative measurement of the native femoral head as a guide for component sizing at different preoperative templating magnifications. Methods: Sixty-nine hips were templated using a magnification of 105.0%, 110.0%, and 115.0%. The native femoral head size was then measured intraoperatively and matched to the correlated head size at the specified preoperative templated magnification. Based on the specified magnification, the corresponding implants were then used as a starting point for component placement. Results: The authors found that measurement of the femoral …

Foundations Of Intramedullary Femoral Shaft Fracture Fixation: Avoidance, Recognition, And Management Of Common Pitfalls, Christopher Kurnik, Jory Wasserburger, William Curtis, Tyler Chavez

Western Journal of Orthopaedics

Intramedullary nailing is an effective treatment of femoral shaft fractures. However, this procedure has several common complications and technical problems that can interfere with full recovery in some patients. The purpose of this review article is to expand on the literature with the authors’ own experiences to summarize the following common complications of femoral nailing: missed injuries, suboptimal surgical timing, malreduction, reaming errors, implant insertion errors, pain-management problems, and implant removal errors. Strategies are also identified to help avoid and manage these complications.

Reaming Errors In Intramedullary Nailing, Kathryn C. Helmig, Samer Kakish, Thomas A. Decoster

Western Journal of Orthopaedics

Reaming for intramedullary implants has biomechanical and biologic benefits. However, there are multiple potential pitfalls in the reaming process. Common errors in reaming for intramedullary implants include: over-reaming or under-reaming the intramedullary canal, reamer incarceration, using dull or narrow-fluted reamers, and poor technique. Being aware of these potential problems with reaming helps surgeons avoid intraoperative issues altogether or diagnose their causes as they arise, decrease complications, and improve efficiency in the operating room.

History Of External Fixation, Thomas A. Decoster

Western Journal of Orthopaedics

No abstract provided.

Front Matter, Arianna Medina

Western Journal of Orthopaedics

No abstract provided.

Emancipatory Nursing Praxis: Applying The Social Justice Theory To Implement Harm Reduction In Prison Substance Use Disorder, Veronica A. Holmes

Theoretical Foundation in Advanced Practice Nursing

The United States has the highest rate of incarceration in the world. Inmates suffer from chronic health conditions and substance use disorder (SUD) at a higher rate than the rest of the population yet, often do not receive sufficient medical care during incarceration. The theory of Emancipatory Nursing Praxis (ENP) calls for the integration of social justice within the profession of nursing. This theory provides a framework in which nurses can awaken and serve as agents of change, working to ameliorate issues of systemic oppression. Harm reduction refers to policies, programs, and strategies aimed at reducing the negative health, economic, …

Demolishing Systemic Ableism: Attention-Deficit Hyperactivity Disorder (Adhd) In Adults, Jessica L. Belisle

Theoretical Foundation in Advanced Practice Nursing

No abstract provided.

Optical And Computational Methods For Detection And Quantification Of Protein-Protein Interactions Using Single-Molecule Localization Microscopy, David James Schodt

Physics & Astronomy ETDs

Interactions between proteins residing on or near the membranes of biological cells trigger many of the signaling cascades that facilitate the transmission of information between the exterior and the interior of the cell. Normal function of these protein-protein interactions (PPIs) is required for the healthy functioning of complex single- and multi-cellular organisms. Abnormalities involving these interactions are implicated in several diseases, such as the progression and treatment resistance of many forms of cancer. Understanding both the normal and abnormal behaviors of these interactions is necessary to improve our understanding of such diseases, which in turn can drive drug development for …

Integrated Grating Couplers On-A-Chip: Characterizations And Applications, Xuemei Wang

Optical Science and Engineering ETDs

We demonstrate two applications based on grating coupled phase matching to a slab waveguide: lab-on-a-chip spectrometer using a transversely chirped grating and indoor lidar plenoptic sensor array for Time of flight (ToF) position mapping system. In the first application, a chirped grating waveguide coupler serves as a spatially dependent narrow-band filter. The transversely-chirped-input grating is fabricated on a SiO₂-Si₃N₄-SiO₂ waveguide atop a Si substrate by interferometric lithography. Light with wavelength from 400- nm to 700 nm couples into Si₃N₄ waveguide through transversely chirped grating incident at a 33.5⁰ angle and …

Robust Uncertainty Quantification With Analysis Of Error In Standard And Non-Standard Quantities Of Interest, Zachary Stevens

Mathematics & Statistics ETDs

This thesis derives two Uncertainty Quantification (UQ) methods for differential equations that depend on random parameters: (\textbf{i}) error bounds for a computed cumulative distribution function (\textbf{ii}) a multi-level Monte Carlo (MLMC) algorithm with adaptively refined meshes and accurately computed stopping-criteria. Both UQ approaches utilize adjoint-based \textit{a posteriori} error analysis in order to accurately estimate the error in samples of numerically approximated quantities of interest. The adaptive MLMC algorithm developed in this thesis relies on the adjoint-based error analysis to adaptively create meshes and accurately monitor a stopping criteria. This is in contrast to classical MLMC algorithms which employ either a …

Machine Learning Model Comparison And Arma Simulation Of Exhaled Breath Signals Classifying Covid-19 Patients, Aaron Christopher Segura

Mathematics & Statistics ETDs

This study compared the performance of machine learning models in classifying COVID-19 patients using exhaled breath signals and simulated datasets. Ground truth classification was determined by the gold standard Polymerase Chain Reaction (PCR) test results. A residual bootstrapped method generated the simulated datasets by fitting signal data to Autoregressive Moving Average (ARMA) models. Classification models included neural networks, k-nearest neighbors, naïve Bayes, random forest, and support vector machines. A Recursive Feature Elimination (RFE) study was performed to determine if reducing signal features would improve the classification models performance using Gini Importance scoring for the two classes. The top 25% of …

Modeling And Performance Analysis Of Deb Based Hydrogen Getters, John A. Matteson

Chemical and Biological Engineering ETDs

Hydrogen getter materials are used to irreversibly absorb hydrogen gas in sealed environments. The DEB based getter system, despite finding widespread use in this application, still posses challenges with respect to experimental performance analysis and fundamental understanding of reaction mechanism. The second chapter of this report addresses the experimental challenges of this getter system by demonstrating the utility and experimental strengths of a custom magnetic suspension balance (MSB) based gravimetric sorption system. This apparatus enables performance evaluation in process relevant conditions including dilute mixed gas environments which our results indicate is necessary for accurate performance evaluation of getter systems. Chapter …

Augmented Reality For Human Control Of Engineering Tasks, Elijah Wyckoff

Mechanical Engineering ETDs

This research is motived by the study of dynamics, especially in experimentation and Structural Health Monitoring (SHM) methods. It is important that inspectors maintain awareness of test structures while observing sensor data and inputting control. Humans receive a large amount of information from vision, and this feedback is crucial to inform decision making. Human-computer interaction (HCI) provides valuable data and information but separates the human from reality as it is necessary to look away from the region of interest to view information on a separate device. Additionally, sensor data does not collect experiment safety, quality, and other contextual information of …

Gp-K: A Probabilistic Method For Hourly Day-Ahead Power Load Forecasting, Miguel A. Hombrados-Herrera

Electrical and Computer Engineering ETDs

The elevated costs that incur power grid stakeholders due to forecasting errors in power load demand have created the need for forecasting methods that provide accurate predictions and allow for assessing the reliability of their predictions. This thesis proposes a probabilistic forecasting method for multi-step ahead forecasting.

In particular, it presents a probabilistic method to perform a 24-hours-ahead power load forecasting that arises as the combination of Gaussian Process regressors with NMF (nonnegative matrix factorization) and integrates the advantages of both methods. Instead of training 24 independent processes for each hour of the predicted day, this work proposes to factorize …

Ultrashort Pulse Laser Filamentation Electrical And Optical Diagnostic Comparison, James E. Wymer

Optical Science and Engineering ETDs

Results presented here examine the effect of changing gas pressure on the radio frequency (RF) emissions of an ultrashort pulse laser filament plasma and how those emissions vary longitudinally in the laser focal region. We use a WR284 rectangular waveguide with a 1.5 cm hole that allows the beam through. A 3.2 GHz microwave signal is emitted in the waveguide, and signals are received through a waveguide-to-coax antenna connected to an HP8470B Schottky diode. By enabling and disabling the 3.2 GHz signal, we measure both the self-emitted RF from a USPL filament and subsequently the degree of attenuation a filament …

Reach - Covid And Flu Vaccine Supplement Listening Sessions Report, Theresa H. Cruz, Camille Velarde

Reports & Documents

No abstract provided.

Control Mechanisms For Adaptive Nanoscale Devices, David Arredondo

Nanoscience and Microsystems ETDs

Nanotechnology promises to revolutionize many areas of applied science including materials, synthetic biology, and medicine. Devices may consist of solution-phase information processing systems or molecular robots. Of particular interest are DNA-based systems due to their composability and relatively simple interactions that are suited to bottom-up design. This work introduces high-level designs of robust control mechanisms for nanoscale devices with immediate applications in molecular computing, synthetic biology, and DNA robotics.

Nanoscale systems are dominated by probabilistic chemical behavior, so engineers must take careful consideration to produce predictable systems. Probabilistic behavior in chemical reaction networks (CRNs) yields deterministic evolution of species concentrations …

The Warrior To Scholar Identity Transformation, Eliberto Trevizo Calderon

Organization, Information and Learning Sciences ETDs

ABSTRACT

This qualitative emergent study investigated the identity transformation experiences of enlisted combat student veterans (ECSVs) from warriors into scholars at the University of New Mexico (UNM). ECSVs are a sub-population of the student veteran community who served in military combat jobs and thus underwent a military indoctrination process that inculcated a warrior identity in them. When ECSVs bring the warrior identity with them to campus, it may conflict with the scholar identity, causing them to struggle to assimilate into the university environment. The study used semi-structured individual interviews and a focus group for data collection and open, thematic, and …

Alterations In Executive Functioning Following Moderate Prenatal Alcohol Exposure: New Translational Insights, Sarah L. Olguin

Biomedical Sciences ETDs

While the lifelong difficulties that result from alcohol exposure in utero are well documented, Fetal Alcohol Spectrum Disorders (FASD) remain the most common neurodevelopmental syndrome. FASD patients struggle with executive control including attention, cognitive control, reward learning, and impulsivity. These self-regulation problems contribute to increased rates of school expulsion, incarceration, and substance use disorders. However, it is still unclear how prenatal alcohol exposure (PAE) affects executive control processes that lead to inappropriate behavior later in life. Here we examined the effect of PAE on 4 aspects of executive functioning paired with intervention or with translatable EEG-like recording, 1) control over …