Digital Commons Network^™

Fluorotelomer Carboxylic Acid Degradation: Implications For Septic Systems, Alexis Marie Eaton

Honors Theses and Capstones

Per- and polyfluoroalkyl substances, or PFAS, are a group of manmade organic chemicals that have been widely used since the 1940’s due to their resistance to heat, water, and oil. These compounds are associated with negative health outcomes including poor thyroid function, reproductive toxicity, and carcinogenicity. Because products with PFAS are widely used in residential settings, and because many PFAS do not completely degrade during wastewater treatment/handling, septic systems may be an important non-point source of PFAS to groundwater. Many homes that have septic systems, which discharge wastewater effluent to the subsurface, also use groundwater as a drinking water source; …

Feminist Environmental Ethics: A Modern, Intersectional Approach, Suzanne E. Scharff

Honors Theses and Capstones

No abstract provided.

Utilizing Gsk3beta And Integrin Inhibitors To Target Stat3 Activity In Triple Negative Breast Cancer, Emily Anne Pratt

Master's Theses and Capstones

Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer associated with poor prognosis and characterized by increased rates of proliferation and metastasis. TNBC gets its name due to the lack of the three receptors commonly found in other breast cancer types: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Breast tumors expressing these receptors can be treated with hormonal therapies, but TNBC tumors will not respond to such treatments and are therefore more difficult to treat. To circumvent this, targeted therapies that inhibit proliferation and migration are of great research …

Occurrence And Fate Of Per- And Polyfluoroalkyl Substances (Pfas) In Atmospheric Deposition, Surface Waters, And Sediments Discharging To The Great Bay Estuary, New Hampshire, Katherine Alexina Wieck

Master's Theses and Capstones

Per- and polyfluoroalkyl substances (PFAS) are a class of several thousand synthetic organic compounds commonly utilized in the manufacturing of consumer products and in industrial processes since their initial development in the 1940s. Although the widespread presence of PFAS in environmental matrices derives from many different industrial and domestic sources, recent studies characterizing their fate in aqueous systems have primarily focused on point source discharge, such as those from wastewater treatment facilities, airports, and industrial complexes. Focusing on point sources neglects atmospheric deposition, an important diffuse background source of PFAS into surface waters and sediments. Furthermore, atmospheric deposition is likely …

Impact Of Hdac Inhibitors On The Efficiency Of Cardiomyocyte Differentiation, Lauren Mary Sargent

Honors Theses and Capstones

Heart disease and injury is the leading cause of death worldwide, with much of its severity caused by the low regenerative capacity of cardiomyocytes (CMs). One of the strategies to counteract the poor regeneration of CMs is the production of CMs via differentiating stem cells. However, the low efficiency of obtaining CMs from stem cells is an issue because there are numerous inconsistencies in the process. Histone deacetylase (HDAC) inhibitors have been researched as ways to increase efficiency of CM differentiation by increasing histone acetylation, and thereby allowing differentiation to occur more efficiently. In this study, the HDAC inhibitor, trichostatin …

Tbp1: An Essential Regulator Of Transcription In Toxoplasma Gondii, Robert Kelly

Master's Theses and Capstones

Transcription is well-conserved across eukaryotes, lending itself to countless studies in model organisms. Still, some early-diverging eukaryotes, such as Apicomplexans, continue to deviate from canonical gene expression. One such Apicomplexan is the single-celled parasite, Toxoplasma gondii. Toxoplasma maintains many elements of conventional eukaryotic transcription but demonstrates a relatively short 8-hour replication time. This suggests that transcription is tightly regulated in these parasites, consistent with their ability to differentiate between life stages per the demand of the host environment. Transcription initiation has, however, remained elusive in Toxoplasma. The formation of a preinitiation complex (PIC) has not been characterized as the parasites …

Enhancing Inpatient Sleep Quality In Patients On An Intermediate Care Unit Through Healthcare Staff Education: A Quality Improvement Project, Avery B. Drouin

Master's Theses and Capstones

Background

In the Intermediate Care Unit (IMCU), patients often suffer from poor sleep quality due to continuous overnight care and inherent hospital environment noise. Poor sleep can adversely affect recovery, especially for cardiac patients, who constitute a significant portion of the IMCU population. Improving sleep quality in these patients is essential for their recovery and overall well-being.

Local Problem

Despite the importance of adequate sleep, only 47% of patients in the hospital that houses the microsystem reported a quiet environment at night using the Hospital Compare online survey platform. Disruptions from alarms, phones, and care activities significantly impact sleep quality, …

A Quality Improvement Initiative To Redefine The Process Of Instrument Decontamination From The Surgical Field In The Operating Room To The Sterile Processing Department., Nicole Dannett Denton

Master's Theses and Capstones

Background: The Operating Room (OR) faces a significant challenge with the increasing presence of bioburdens on instruments. Research-based on evidence has demonstrated the critical role of precleaning at the point of care with sterile water in reducing bioburden incidence. While current practices recommend the use of an enzymatic solution post-procedure to spray instruments, it is clear that a more comprehensive approach is needed to effectively manage bioburdens and reduce the risk of Surgical Site Infections (SSI).

Methods: Utilizing the Plan-Do-Study-Act (PDSA) model to create a Quality Improvement (QI) solution, the project leader recommended using sterile water at the point of …

Improving The Postpartum Depression Discharge Education To Increase Quality And Safety Of Care: A Quality Improvement Initiative, Amanda Lucia

Master's Theses and Capstones

Background: Postpartum depression (PPD) is the most prevalent psychological condition to affect mothers following childbirth which can have detrimental consequences on the physical and mental health of the mother, child, and spouse (Wang et al., 2021). Globally, postpartum depression affects 17.2% of the world population, and in the United States 1 in 8 women who recently gave birth reported symptoms of PPD, and 1 in 10 women reported experiencing a major depressive episode within a year following delivery (CDC, 2023). Patients’ spouses and family members are in a unique position to identify early manifestations of PPD which can lead to …

Seagrassnet Monitoring Program 2024 - 2028: Quality Assurance Project Plan, Trevor Mattera, Lara Martin, Nathaniel Gruen, Kalle Matso, David Burdick

PREP Reports & Publications

No abstract provided.

Asynchronous Movement Patterns Between Breeding And Stopover Locations In A Long-Distance Migratory Songbird, Theodore Zenzal, Andrea Contina, Hannah Vander Zanden, Leanne Kuwahara, Daniel Allen, Kristen Covino

Faculty Publications

The species-specific migratory patterns and strategies of many songbirds remain unknown or understudied, as research in animal ecology is biased toward the breeding period, with the fewest studies on the migratory period across taxa. Identifying large-scale spatiotemporal migratory patterns is challenging, as individuals within a species may vary in their migratory behavior and strategies. The Yellow Warbler (Setophaga petechia) is a Nearctic-Neotropical migrant that is relatively well studied during the breeding season, but its species-wide migratory patterns remain understudied. Our aim in studying Yellow Warbler movement ecology was to characterize temporal migration patterns during fall migration. We sought to determine …

Unh/Noaa Joint Hydrographic Center 2024 Performance And Progress Report Executive Summary, Larry A. Mayer

Center for Coastal and Ocean Mapping

Reporting Period: 01/01/2023–12/31/2023

Ecosystem Functions And Services​ Landscaping For Water Quality – April 30, 2024​ Sunapee, Nh​, Julia Peterson

UNH Cooperative Extension

No abstract provided.

Assessing And Understanding Soil Characteristics​, Amy Papineau

UNH Cooperative Extension

No abstract provided.

Asynchronous Movement Patterns Between Breeding And Stopover Locations In A Long-Distance Migratory Songbird, Theodore Zenzal, Andrea Contina, Hannah Vander Zanden, Leanne Kuwahara, Daniel Allen, Kristen Covino

Faculty Publications

The species-specific migratory patterns and strategies of many songbirds remain unknown or understudied, as research in animal ecology is biased toward the breeding period, with the fewest studies on the migratory period across taxa. Identifying large-scale spatiotemporal migratory patterns is challenging, as individuals within a species may vary in their migratory behavior and strategies. The Yellow Warbler (Setophaga petechia) is a Nearctic-Neotropical migrant that is relatively well studied during the breeding season, but its species-wide migratory patterns remain understudied. Our aim in studying Yellow Warbler movement ecology was to characterize temporal migration patterns during fall migration. We sought to determine …

Halpin Named Fellow Of American Physiological Society, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Unh Celebrates Students And Alumni At Annual Social Venture Innovation Challenge, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Contextualizing Singlehood Among Young Adults: Exploring The Meanings And Perceived Reasons For Being Single, Jonathon J. Beckmeyer, Tyler B. Jamison

Faculty Publications

Objective: We explored how young adults discussed their experiences with singlehood and their reasons for being single.

Background: Despite singlehood being normative during young adulthood, less research has focused on the diversity of singlehood compared to that of romantic involvement.

Method: In Study 1, 35 young adults participated in in-depth qualitative interviews about their romantic histories. We explored singlehood meanings and reasons in the context of their relationship histories. In Study 2 we used data from 155 single young adults to explore the factor structure, internal reliability, and initial validity of the Reasons for Being Single (RBS) scale, which we …

Laboratory Investigations Into Alternative Baits For The Channeled Whelk (Busycotypus Canaliculatus) Fishery, Mary Kate Munley, Elizabeth A. Fairchild, Steven H. Jury, Winsor H. Watson, Shelley A. Edmundson

Faculty Publications

Channeled whelks (Busycotypus canaliculatus) are fished along the eastern US coast using traps typically baited with pieces of female horseshoe crabs (HSC Limulus polyphemus). However, the use of HSC as bait, particularly females, is controversial because they are already heavily fished because their blood contains a substance that the biomedical industry uses to manufacture a test for pathogenic bacteria. Therefore, the goals of this study were to: 1) develop a cost-effective alternative bait that does not rely on HSCs and 2) determine whether whelk are more attracted to female HSC pieces than male HSC pieces. Seventeen different baits were tested …

Laboratory Investigations Into Alternative Baits For The Channeled Whelk (Busycotypus Canaliculatus) Fishery, Mary Kate Munley, Elizabeth A. Fairchild, Steven H. Jury, Winsor H. Watson, Shelley A. Edmundson

Faculty Publications

Channeled whelks (Busycotypus canaliculatus) are fished along the eastern US coast using traps typically baited with pieces of female horseshoe crabs (HSC Limulus polyphemus). However, the use of HSC as bait, particularly females, is controversial because they are already heavily fished because their blood contains a substance that the biomedical industry uses to manufacture a test for pathogenic bacteria. Therefore, the goals of this study were to: 1) develop a cost-effective alternative bait that does not rely on HSCs and 2) determine whether whelk are more attracted to female HSC pieces than male HSC pieces. Seventeen different baits were tested …

How Efficient Is The Ocean At Taking Up Carbon?, Rebecca Irelan

UNH Today Archive

No abstract provided.

Youth Identity And Postsecondary Decision Making In A Rural State: Evidence Of A College For All Master Narrative, Jayson Seaman, Cindy L. Hartman, Andrew D. Coppens, Erin H. Sharp, Sarah Jusseaume, Molly Donovan

Faculty Publications

This study examined the normative messages that inform youth postsecondary decision making in a predominantly rural state in the northeastern U.S., focusing on the institutionalization and circulation of identity master narratives. Using a multilevel, ecological approach to sampling, the study interviewed 33 key informants in positions of influence in educational, workforce, and quality of life domains. Narrative analysis yielded evidence of a predominant master narrative – College for All – that participants described as a prescriptive expectation that youth and families orient their postsecondary planning toward four-year, residential baccalaureate degree programs. Both general and domain-specific aspects of this master narrative …

Winners Announced: 2023 Social Venture Innovation Challenge, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

Advancing Discovery With Two New Mass Spectrometers, Beth Potier

UNH Today Archive

No abstract provided.

How Could Ocean Acidification Impact New England’S Fisheries?, Maeve Gifford

UNH Today Archive

No abstract provided.

Tales Out Of School: Delineating Student Speech Protections For The Digital Age, Jason Zenor

The University of New Hampshire Law Review

The way students communicate has also changed greatly over the last generation, but in the first two decades of 21st Century, the U.S. Supreme Court had yet to answers questions about the extent of power for school administrators to control off-campus speech on digital technologies. Then in the case of Mahanoy Area School District v. B.L (2021) the U.S. Supreme Court finally answered this question by holding that administrators do have the ability to control off-campus speech. The Court did give some specific scenarios in which administrators had power to regulate off-campus, but it did not give a bright-line rule. …

Birth Right: Does A Lack Of Access To Health Coverage For Fertility Treatment For Single Individuals And Same-Sex Couples Constitute Discrimination?, Quinn Kobrin

The University of New Hampshire Law Review

There are often great costs associated with receiving fertility treatments such as IVF. Those who wish to overcome infertility and conceive may turn to their health insurance providers to find coverage for such treatments. Currently, many health insurance providers’ policies require that those seeking coverage show infertility either by (1) failing to conceive after six to twelve months of unprotected sexual intercourse; or (2) failing to conceive after six to twelve months of receiving fertility treatment. Advocates argue that such policies are discriminatory because classes of people such as same-sex couples and single individuals1 who wish to conceive cannot do …

Controls Of Benthic Microbial Communities In Headwater Streams Across A Land Use Gradient In Northeastern Usa, Joshua Michael Buonpane

Master's Theses and Capstones

Benthic microbes are important drivers of biogeochemical cycling in streams, influencing the storage, transformation, and emission of carbon and nutrients. While the impact of land use and land cover on water quality has been extensively studied, the connection between water quality and microbial community composition and function remains unresolved. In this study, we examined how the water quality changes accompanying watershed development impact the diversity, composition, and functional potential of benthic bacterial/archaeal, and fungal communities. This was explored in headwater streams across an urbanization gradient in the northeastern US. We did not find a link between urbanization and α-diversity of …

Ratiometric Fluorescent Sensors Based On Non-Covalent Crosslinked Molecular Imprinted Polymers, Yuan Chen

Doctoral Dissertations

This thesis describes a series of optical chemosensors based on FRET between fluorophores on the polymer and the substrate. It involved the preparation of the polymer and nanoparticles for the chemosensor, and the sensing behavior based on the preparation methods.A photophysically inert sensor matrix was prepared by a robust and simple emulsion method. Stannic oxide encapsulated silica nanoparticles with diameters between 25 and 70 nm have been prepared by one-pot reverse-phase emulsion methodology. The constituents and core/shell morphology of the nanoparticles were demonstrated by electron microscopic technology, energy-dispersive X-ray spectroscopy (EDS) and X-ray photoelectron spectroscopy (XPS). X-ray diffraction (XRD) was …

Exploring The Mechanistic Effects Of Surface Characteristics On Uv254 And Bl405 Disinfection Efficacy, Castine Annastasia Bernardy

Doctoral Dissertations

The COVID-19 pandemic highlighted the need for more robust surface disinfection technologies. Photoinactivation efficacy for microbial pathogens and many surrogates has been well studied for water disinfection. However, there is a limited body of knowledge from research on surface disinfection applications of these technologies. The onset of the global pandemic resulted in a dramatic increase in surface disinfection devices being marketed to consumers, yet regulations for such devices have not been developed. This doctoral research studies the inactivation efficacy of two wavelengths, UV254 and BL405. The objective of this doctoral dissertation was to expand the body of knowledge required to …