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Articles 241 - 270 of 17645
Full-Text Articles in Entire DC Network
People Who Moved In The Mountain West, 2024, Anthony Arroyo, Sydney Mitchell, Maisoon Faris, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.
People Who Moved In The Mountain West, 2024, Anthony Arroyo, Sydney Mitchell, Maisoon Faris, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.
Cities & Metros
This fact sheet presents 2024 data on state and city-level mobility rates across the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. Point2Homes’ “Mobility Rates Reach Record Low: In 2024, Americans Moved Less Than Ever” report provides data on mobility rates within states, as well as the rate of new residents moving into states and cities across the U.S. This fact sheet highlights mobility rates within Mountain West states, the rate of new residents moving into Mountain West states, and the rate of new residents moving into 63 Mountain West cities. This fact sheet also includes national …
The New Era Of Pulmonary Hypertension: The Dawn Of Disease Modification & Therapeutic Modalities, Noyan Ramazani, Lacey Barnes, Alex Wong, Divyansh Sharma, Aditi Singh, Kachon Lei
The New Era Of Pulmonary Hypertension: The Dawn Of Disease Modification & Therapeutic Modalities, Noyan Ramazani, Lacey Barnes, Alex Wong, Divyansh Sharma, Aditi Singh, Kachon Lei
Department of Internal Medicine Faculty Research
Pulmonary hypertension (PH) can be defined as a mean pulmonary artery pressure (mPAP) greater than 20 mm Hg at rest during right heart catheterization (RHC). The reported prevalence of PH throughout the globe has been estimated to impact approximately 1% of the total population, with a majority of those afflicted being women more than men. Numerous etiologies give rise to the pathophysiology of PH, including heart disease (i.e., left-sided heart failure), lung diseases, and other unclear causes related to chronic stages and complications surrounding long-standing pulmonary thromboembolisms, side effects of certain medications, and genetic and environmental factors. Untreated PH can …
170 Silent Stories: Gendered Violence Beneath The American Dream, Kayla Lockwood
170 Silent Stories: Gendered Violence Beneath The American Dream, Kayla Lockwood
Graduate & Professional Student Association Research Forum
170 Silent Stories: Gendered Violence Beneath the American Dream is a presentation drawn from my MFA thesis exhibition, read the fine print, which critically examines how postwar American domestic ideals—particularly those emerging in the 1950s—were constructed through visual culture, policy, and design. The project investigates how the American Dream promised stability, prosperity, and safety while simultaneously normalizing rigid gender roles, domestic containment, and gendered violence.
At the center of the exhibition is 170 Silent Stories (2026), an installation composed of 170 cast-aluminum high heels, each representing a documented domestic violence case in 1950s New York. The high heel, a deeply …
A Rare Presentation Of Extra-Appendiceal Mucinous Neoplasm Of The Anus, Pincus Joshua, Marianne Estrada, Lance Horner University Of Nevada, Las Vegas
A Rare Presentation Of Extra-Appendiceal Mucinous Neoplasm Of The Anus, Pincus Joshua, Marianne Estrada, Lance Horner University Of Nevada, Las Vegas
School of Medicine Research Poster Showcase
Introduction: Mucinous neoplasm of the anus is an uncommon malignancy, representing less than 3% of all anal cancers. Even more rare is extra-appendiceal mucinous neoplasm. As a result, limited literature exists to define diagnostic strategies and optimal management. Our case report details the presentation and management of a patient with recurrent mucinous neoplasm of the anus. Methods: A retrospective chart review was performed which includes clinic documentation., operative notes, pathology reports. Results: The patient is a 76-year-old male with a history of T3N0M0 anal mucinous carcinoma diagnosed in 2015 and treated with neoadjuvant chemoradiation with complete pathological response. In 2024, …
Clustering Of Internet Behaviors And Associated Mental Health Outcomes Among U.S. Adolescents, Aakansha Singh, Timothy Grigsby, Miguel Fudolig, Ying Guo, Clariana Ramos De Oliveira
Clustering Of Internet Behaviors And Associated Mental Health Outcomes Among U.S. Adolescents, Aakansha Singh, Timothy Grigsby, Miguel Fudolig, Ying Guo, Clariana Ramos De Oliveira
School of Medicine Research Poster Showcase
Poster: Clustering of Internet behaviors and associated mental health outcomes among U.S. adolescents
Quick! Which Scanner Should The Patient Go To?, Nicholas Johnson, Farnaz Norozian
Quick! Which Scanner Should The Patient Go To?, Nicholas Johnson, Farnaz Norozian
School of Medicine Research Poster Showcase
Introduction Rarely does a pediatric patient have a stroke, but when they do what imaging modality is best suited? EMS tele comes in activating a stroke alert. An 11 year old otherwise healthy male presented with 10 hours of left sided sensation changes, waking up with dense left hemiparesis.14 days prior he had been on amusement park rides resulting in headache with vomiting since resolved. On arrival, slight hypertension for age otherwise hemodynamically stable, glucose normal, EKG demonstrated sinus rhythm. No history of genetic blood or clotting disorder. PICU and ER attendings discussion resulted in MRI as the initial imaging …
Horseshoe Kidneys In Transplantation: Underutilization Despite Comparable Quality And Favorable Outcomes: Unos Registry Analysis (2007-2023), Abigail W. Cheng, Samrawi Misiker, Roberto Sagaribay, Kavita Batra
Horseshoe Kidneys In Transplantation: Underutilization Despite Comparable Quality And Favorable Outcomes: Unos Registry Analysis (2007-2023), Abigail W. Cheng, Samrawi Misiker, Roberto Sagaribay, Kavita Batra
School of Medicine Research Poster Showcase
Introduction: Horseshoe kidneys (HSKs) are the most common renal fusion anomaly, occurring in approximately 1 in 500 individuals and often discovered incidentally. Historically excluded from transplantation due to complex anatomy, advances in surgical techniques have made HSK transplantation increasingly feasible. Although successful procurement and transplantation have been described in case reports, national-level data comparing donor characteristics and organ utilization between HSK and non-HSK donors remain limited. This study characterizes donor demographics, clinical profiles, and organ utilization of HSK donors using the United Network for Organ Sharing (UNOS) database.
Methods: A retrospective analysis of the UNOS kidney transplant registry was performed, …
Does What Happens In Vegas Increase Pedestrian Safety? A Longitudinal Study On The Effectiveness Of Pedestrian Bridges, Jalen Paulos, Jalen Paulos, Joaquin Del Mundo, Brock Wentz
Does What Happens In Vegas Increase Pedestrian Safety? A Longitudinal Study On The Effectiveness Of Pedestrian Bridges, Jalen Paulos, Jalen Paulos, Joaquin Del Mundo, Brock Wentz
School of Medicine Research Poster Showcase
Urban populations continue to rise and the frequency that pedestrians are exposed to vehicular traffic continues to increase. The result is an increase in automobile versus pedestrian collisions. This study aims to determine the efficacy of pedestrian bridges in reducing the rates of automobile-pedestrian collisions. Data for all automobile versus pedestrian collisions and injuries from July of 1997 through December of 2023 at four distinct intersections along Las Vegas Boulevard were retrieved from the Nevada Department of Transportation. These sites were chosen because of their historically high rates of automobile versus pedestrian incidents and the construction of pedestrian bridges at …
The Death Penalty & State Executions In The Mountain West, 1976 - 2024, Mia Tschan, Sydney Mitchell, Yiselle Olivas Ruiz, Dre Boyd-Weatherly, Olivia K. Cheche, Kristian Thymianos, Caitlin J. Saladino, William E. Brown Jr.
The Death Penalty & State Executions In The Mountain West, 1976 - 2024, Mia Tschan, Sydney Mitchell, Yiselle Olivas Ruiz, Dre Boyd-Weatherly, Olivia K. Cheche, Kristian Thymianos, Caitlin J. Saladino, William E. Brown Jr.
Criminal Justice
This fact sheet presents 1976-2024 data on the death penalty and state executions in the five Mountain West states of Arizona, Colorado, New Mexico, Nevada, and Utah. The Death Penalty Information Center (DPIC) report, “State Execution Rates,” includes data on the 36 states that have conducted state executions and the 38 states, federal government, and military institutions that imposed the death penalty between 1976 and 2024. This fact sheet focuses on cumulative executions, executions per capita, and executions per death sentence in each Mountain West state.
Does What Happens In Vegas Increase Pedestrian Safety? A Longitudinal Study On The Effectiveness Of Pedestrian Bridges, Jalen Paulos, Joaquin Miguel Del Mundo, Brock Wentz, Janel Pietryga
Does What Happens In Vegas Increase Pedestrian Safety? A Longitudinal Study On The Effectiveness Of Pedestrian Bridges, Jalen Paulos, Joaquin Miguel Del Mundo, Brock Wentz, Janel Pietryga
Department of Orthopaedics Faculty Research
Urban populations continue to rise and the frequency that pedestrians are exposed to vehicular traffic continues to increase. The result is an increase in automobile versus pedestrian collisions. This study aims to determine the efficacy of pedestrian bridges in reducing the rates of automobile‒pedestrian collisions. Data for all automobile versus pedestrian collisions and injuries from July 1997 through December 2023 at four distinct intersections along Las Vegas Boulevard were retrieved from the Nevada Department of Transportation. These sites were chosen because of their historically high rates of automobile versus pedestrian incidents and the construction of pedestrian bridges at three of …
Does What Happens In Vegas Increase Pedestrian Safety? A Longitudinal Study On The Effectiveness Of Pedestrian Bridges, Jalen Paulos, Joaquin Miguel Del Mundo, Brock Wentz, Janel Pietryga
Does What Happens In Vegas Increase Pedestrian Safety? A Longitudinal Study On The Effectiveness Of Pedestrian Bridges, Jalen Paulos, Joaquin Miguel Del Mundo, Brock Wentz, Janel Pietryga
Department of Orthopaedics Faculty Research
Urban populations continue to rise and the frequency that pedestrians are exposed to vehicular traffic continues to increase. The result is an increase in automobile versus pedestrian collisions. This study aims to determine the efficacy of pedestrian bridges in reducing the rates of automobile‒pedestrian collisions. Data for all automobile versus pedestrian collisions and injuries from July 1997 through December 2023 at four distinct intersections along Las Vegas Boulevard were retrieved from the Nevada Department of Transportation. These sites were chosen because of their historically high rates of automobile versus pedestrian incidents and the construction of pedestrian bridges at three of …
Bravery And Bayonets: The Nigerian Regiment And The Battle Of Bweho Chini, September 1917, Paul Cronin
Bravery And Bayonets: The Nigerian Regiment And The Battle Of Bweho Chini, September 1917, Paul Cronin
Calvert Undergraduate Research Awards
The First World War in East Africa spanned the entirety of the war, from 1914 to 1918, and by the end of the war nearly all of the personnel on both sides were African. Understanding how the war in East Africa was different geographically and militarily from the western front helps to shed light on the unique experience of the men who fought there. My thesis builds on the thesis of Ibiang O. Ewa, that the Nigerian Regiment was crucial to allied victory in the campaign, in his chapter in Africa and the First World War: Remembrance, Memories, and Representations …
Navigating Sustainable Burial In Southern Nevada, Kristen Gibson
Navigating Sustainable Burial In Southern Nevada, Kristen Gibson
Calvert Undergraduate Research Awards
Navigating Sustainable Burial in Southern Nevada investigates the accessibility of environmentally conscious end-of-life options for individuals throughout the region. Sustainable burial practices, including green burial, water cremation, and natural organic reduction, provide alternatives to traditional burial and cremation methods. Research was conducted through an analysis of Nevada statutes, local reporting, funeral service resources, and public discussions related to sustainable burial. The research revealed that although Nevada expanded legal recognition of sustainable burial by legalizing natural organic reduction, public access to clear information and available services remains limited. These findings informed the creation of a choose-your-own-adventure booklet designed to translate legal …
Ecovoltaic Solar Energy Development Creates Novel Microclimate, Temperature, And Soil Moisture Patterns Under Solar Panels In A Warm Desert, Juan Pinos, Seth M. Munson, Claire C. Karban, Matthew D. Petrie
Ecovoltaic Solar Energy Development Creates Novel Microclimate, Temperature, And Soil Moisture Patterns Under Solar Panels In A Warm Desert, Juan Pinos, Seth M. Munson, Claire C. Karban, Matthew D. Petrie
Life Sciences Faculty Research
Background As solar energy development expands in desert regions, new installation practices and solar technologies seek to balance ecosystem conservation and energy generation (ecovoltaics). The Gemini Solar Project, a large ecovoltaic facility located in the northeastern Mojave Desert, employed low impact installation methods to reduce disturbance of the desert ecosystem within arrays of bifacial panels mounted on solar tracking systems. We evaluated microclimate and environmental conditions across five locations: four within-facility microsites (underneath solar panels, east and west panel driplines, and interspaces between panel rows) and one in the undisturbed desert outside the facility. Results Under panel microsites experienced lower …
Stakhanov Lives Forever: How Art And Culture Outlasted Politics In The Communist World, Samuel Shewmake
Stakhanov Lives Forever: How Art And Culture Outlasted Politics In The Communist World, Samuel Shewmake
Calvert Undergraduate Research Awards
The Stakhanovite movement and its long term consequences has been heavily debated in the field of Soviet history for several decades. The dominant scholarly narrative is that the Stakhanovite movement and Stakhanovism were largely extinguished during the period following the buildup to the Second World War. Previous works have relied heavily on solely political analysis of the movement, presuming that its character was primarily state-driven with little social component. This paper analyzes the social and artistic legacy of the Stakhanovite movement through novel analysis of film, music, and art of the Stakhanovite period and following decades. Contrary to what has …
No Fue Un Accidente: The Fascist Fantasy Of Self-Victimization In Alfonso Ponce De León’S Autorretrato (1936), Geovany Uranda
No Fue Un Accidente: The Fascist Fantasy Of Self-Victimization In Alfonso Ponce De León’S Autorretrato (1936), Geovany Uranda
Calvert Undergraduate Research Awards
During the eve of the Spanish Civil War (1936 - 1939) Alfonso Ponce de León, a Falange propagandist and artist, created Autorretrato (1936), a self-portrait inspired by an automobile accident he experienced. He exhibited this work several months before his arrest, torture, and execution by Republican forces. This paper analyzes the self-portrait as a fascist work of self-victimization and ideological myth-making in line with fascist propaganda of the time. The painting presents Ponce de León as a dead or dying figure staged through the visual language of Catholic martyrdom. Drawing from Baroque compositional practices and iconographic tropes associated with the …
Nevada Science Olympiad, Christian Ison
Nevada Science Olympiad, Christian Ison
Community Engagement Expo Research Posters
Since 2022, the UNLV School of Integrated Health Sciences has partnered with the Clark County School District to engage and inspire Nevada students through innovative STEM education initiatives. This ongoing collaboration supports the development and hosting of competitive STEM tournaments at the University of Nevada, Las Vegas, providing students with opportunities to explore science, technology, engineering, and mathematics while fostering critical thinking, academic achievement, and future workforce development.
Community Engagement Through Robotics Mentoring – Unlv, First Nv, And High School Robotics Teams, Brendan O'Toole
Community Engagement Through Robotics Mentoring – Unlv, First Nv, And High School Robotics Teams, Brendan O'Toole
Community Engagement Expo Research Posters
The UNLV Robotics Mentorship program includes a two-semester course that trains students to support local high school FIRST Robotics Competition (FRC) teams. ‘ME 464 Robotics Mentoring I’ provides training in design, mentoring, fabrication, and programming. ‘ME 465 Robotics Mentoring II’, pairs students with local high school teams to serve as technical mentors for the competition season.
From Exhibition To Engagement: The Development Of A Community Engagement Ecosystem At The Marjorie Barrick Museum Of Art, Zida Wang
Community Engagement Expo Research Posters
This poster examines how the Marjorie Barrick Museum of Art at the University of Nevada, Las Vegas has developed a community engagement ecosystem through exhibitions, public programming, partnerships, and educational initiatives. Using the Living Here exhibition as a case study, the project demonstrates how university museums can function as community-centered spaces that foster dialogue, belonging, and civic participation. The poster highlights collaborative partnerships, oral history initiatives, student learning opportunities, K–12 engagement programs, and the future expansion of Living Here as a national traveling exhibition. The model positions community engagement as an ongoing process that extends beyond individual exhibitions and supports …
Tech Trekker, Erika Marti, Yania Avila
Tech Trekker, Erika Marti, Yania Avila
Community Engagement Expo Research Posters
We are a team of faculty and students in STEM fields who are dedicated to providing cutting-edge technology to teachers and students in Las Vegas and nearby communities.
Our Mission: Our primary mission is to increase student exposure to and engagement in modern science and engineering tools in order to encourage students into high-demand STEM fields.
Beyond The Chart: Clinical Decisions That Protect Patients, Stephanie Bell Kelsey, Rhea May Brasi, Carlisa Caso, Tida Chitmongran, Kieaira Cooksey, Erika Ferrell, Jacqueline Franke, Aizel Joyce Garrido, Lidia Geberslassie, Laurie Gillmore, Theo Hipos, Mindi Johnson, Heimy Jun, Robin Kanaan, Jiahui Li, Alexis Mangubat, Katia Marcu, Sara Mccarthy, Adithya Nath, Brenda Orozco, Maria Papageorge, Elizabeth Ruckman, Debbie Salcido, Aleczandrea Schmelzle, Vivian Stark, Kara Traynor
Beyond The Chart: Clinical Decisions That Protect Patients, Stephanie Bell Kelsey, Rhea May Brasi, Carlisa Caso, Tida Chitmongran, Kieaira Cooksey, Erika Ferrell, Jacqueline Franke, Aizel Joyce Garrido, Lidia Geberslassie, Laurie Gillmore, Theo Hipos, Mindi Johnson, Heimy Jun, Robin Kanaan, Jiahui Li, Alexis Mangubat, Katia Marcu, Sara Mccarthy, Adithya Nath, Brenda Orozco, Maria Papageorge, Elizabeth Ruckman, Debbie Salcido, Aleczandrea Schmelzle, Vivian Stark, Kara Traynor
Nursing 711 Class Projects
The cases in this collection were written by graduate nursing students enrolled in the Master of Nursing program at the University of Nevada, Las Vegas School of Nursing. Each author drew from their own clinical experience to illustrate how structured reasoning shapes patient care at the bedside and beyond. Their willingness to reflect honestly on moments of uncertainty, advocacy, and judgment — and to share those reflections with students who are still developing their own — is the foundation of this work. This collection exists because of their generosity.
Retirement Rankings In The Mountain West, 2025, Isabelle G. Graham, Mia Tschan, Anthony Arroyo, Kristian Thymianos, Caitlin J. Saladino, William E. Brown Jr.
Retirement Rankings In The Mountain West, 2025, Isabelle G. Graham, Mia Tschan, Anthony Arroyo, Kristian Thymianos, Caitlin J. Saladino, William E. Brown Jr.
Demography
This fact sheet reports 2025 data on retirement rankings in the five Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The Bankrate report, “America’s best states to retire in 2025: New Hampshire takes the top spot,” presents data on retirement rankings for all 50 U.S. states. This fact sheet focuses on the overall retirement rank and individual retirement category rankings for each Mountain West state.
Data Centers In Mountain West Markets, 2026, Cason Noll, Krish Sharma, Maisoon Faris, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.
Data Centers In Mountain West Markets, 2026, Cason Noll, Krish Sharma, Maisoon Faris, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.
Transportation & Infrastructure
This fact sheet reports on the distribution and geographic concentration of data centers across the Mountain West states of Arizona, Colorado, Nevada, New Mexico and Utah as of March 6th, 2026. Using data from DataCenterMap, this fact sheet examines the number of data centers in each Mountain West state and further analyzes market-level distribution, defined as cities within each state where data centers are located. The data are used to compare state totals and to rank Mountain West markets from highest to lowest based on the number of data centers operating in that area.
Factors Associated With Immediate Postnatal Care In Lao People’S Democratic Republic: An Analysis Of The 2017 Lao People’S Democratic Republic Multiple Indicator Cluster Survey, Tressa Quayle, Jinyoung Kim, Jennifer Pharr, Rebecca Benfield
Factors Associated With Immediate Postnatal Care In Lao People’S Democratic Republic: An Analysis Of The 2017 Lao People’S Democratic Republic Multiple Indicator Cluster Survey, Tressa Quayle, Jinyoung Kim, Jennifer Pharr, Rebecca Benfield
Nursing Faculty Research
Background: The World Health Organization recognizes that approximately half of all maternal deaths occur in the immediate postnatal period or 24 h after birth. Forty-seven percent of Lao women aged 15–49 who delivered a baby in the last two years received a postnatal health check in the frst two days after delivery. After leaving the presence of a provider, 98.5% of these women never received another postnatal check. The maternal mortality ratio (MMR) in Lao PDR was 126 deaths per 100,000 live births in 2020. Immediate postnatal care (PNC) is a crucial step to improving maternal mortality. The aim of …
Sigrescuer: A Pan-System Framework For Noise Correction And Mutational Signature Identification Across Sequencing Platforms, Peter T. Nguyen, Maria Zhivagui
Sigrescuer: A Pan-System Framework For Noise Correction And Mutational Signature Identification Across Sequencing Platforms, Peter T. Nguyen, Maria Zhivagui
Nevada Institute of Personalized Medicine Faculty Research
Introduction: Mutational signatures serve as molecular fingerprints of the biological processes and exposures that shape cancer genomes. However, accurate signal recovery remains challenging due to pervasive background variants, sequencing artifacts, technical noise, and platform-specific biases that obscure true mutagenic patterns, hampering biomarker discovery, and mechanistic interpretation. Methods: Here we introduce SigRescueR, a rigorous, pan-system, computational framework based on Bayesian inference designed for noise correction and mutational signature identification. SigRescueR applies statistically robust baseline correction to effectively disentangle true mutational signals from confounding noise and artifacts. Results: When applied to extensive datasets spanning experimental models and human cancers, SigRescueR reliably identified …
Domestic Violence In The Mountain West, 2026, Isabelle G. Graham, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.
Domestic Violence In The Mountain West, 2026, Isabelle G. Graham, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.
Criminal Justice
This fact sheet presents 2026 data on domestic violence in the five Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The World Population Review report, “Domestic Violence by State 2026,” reports data on the percentage of women and men in each state who report experiences of domestic violence in their lifetime.This fact sheet highlights state-level data on different forms of domestic violence reported across the Mountain West.
The Price Of Democracy: The Revolutionary Power Of Taxation In American History, Vanessa Williamson
The Price Of Democracy: The Revolutionary Power Of Taxation In American History, Vanessa Williamson
Brookings Scholar Lecture Series
As part of the Brookings Scholar Lecture Series, Brookings Mountain West presented a lecture titled, "The Price of Democracy: The Revolutionary Power of Taxation in American History" by Brookings senior fellow in governance studies, Vanessa Williamson.
From tariffs to “no tax on tips”, taxation has often been a hot topic in American elections. What is not commonly recognized, however, is that—from the framing of the Constitution to the decades-long backlash to the civil rights movement—taxes have been at the heart of battles over the breadth of our democracy. Brookings senior fellow Vanessa Williamson discusses her new book, The Price of …
From One-Shots To Gems: Building Scaffolded Microcredentials In Information Literacy, Layla Barati, Kevin Sebastian
From One-Shots To Gems: Building Scaffolded Microcredentials In Information Literacy, Layla Barati, Kevin Sebastian
Library Faculty Research
Discover how UNLV Libraries redesigned first-year information literacy instruction into the GEM Knowledge Series—scaffolded microcourses awarding stackable badges. Learn how this model moves beyond traditional one-off library lessons, embeds assessment, and empowers students to Gather, Evaluate, and Make knowledge across academic, professional, and civic contexts.
Social Media And E-Cigarette Use In Youth: Does Depression Play A Mediating Role?, Soumya Upadhyay, Mohammad Karim, Shivank Chhaya
Social Media And E-Cigarette Use In Youth: Does Depression Play A Mediating Role?, Soumya Upadhyay, Mohammad Karim, Shivank Chhaya
Healthcare Administration and Policy Faculty Research
About 28% of middle and high school students report the use of e-cigarettes per the 2019 NYTS survey. Social media can seclude a youth into limited set of beliefs, including affirmation for e-cigarette use. Internalizing problems like depression may be due to overuse of social media, and youth with depressive symptoms are more likely to use e-cigarettes to cope. National Youth Tobacco Survey (NYTS) 2023 data was used (n = 18 143) in a cross-sectional design. Ever e-cigarette use was the binary (Y/N) dependent variable. Independent variable, social media use, was categorized as “never,” “nondaily,” “daily.” Mediator variable, presence of …
The Role Of The Virb Ligand Ctp In The Molecular Mechanism Of Transcriptional Anti-Silencing In Shigella Flexneri, Taylor M. Gerson, Monika M A Karney, Helen Wing
The Role Of The Virb Ligand Ctp In The Molecular Mechanism Of Transcriptional Anti-Silencing In Shigella Flexneri, Taylor M. Gerson, Monika M A Karney, Helen Wing
Life Sciences Faculty Research
In bacteria, nucleoid-structuring proteins bind and constrain DNA, often leading to transcriptional silencing. In Shigella spp., the histone-like nucleoid-structuring protein H-NS silences many genes on the large virulence plasmid. Upon a shift to human body temperature, VirB, a DNA-binding protein and key transcriptional regulator of the Shigella virulence cascade, is produced. VirB counteracts H-NS-mediated transcriptional silencing and belongs to a fast-evolving clade of the ParB superfamily. Like other ParB proteins, VirB binds the ligand CTP. While CTP is essential for the anti-silencing activity of VirB, the role of CTP in the mechanism of VirB-dependent anti-silencing has yet to be …