Digital Commons Network^™

Europium Sulfide Nanoprobes Predict Antiretroviral Drug Delivery Into Hiv-1 Cell And Tissue Reservoirs, Jonathan Herskovitz, Mahmudul Hasan, Jatin Machhi, Insiya Mukadam, Brendan M. Ottemann, James R. Hilaire, Christopher Woldstad, Joellyn Mcmillan, Yutong Liu, Javier Seravalli, Anandakumar Sarella, Howard E. Gendelman, Bhavesh D. Kevadiya

Department of Biochemistry: Faculty Publications

Background: Delivery of long-acting nanoformulated antiretroviral drugs (ARVs) to human immunodeficiency virus type one cell and tissue reservoirs underlies next generation antiretroviral therapeutics. Nanotheranostics, comprised of trackable nanoparticle adjuncts, can facilitate ARV delivery through real-time drug tracking made possible through bioimaging platforms. Methods: To model HIV-1 therapeutic delivery, europium sulfide (EuS) nanoprobes were developed, characterized and then deployed to cells, tissues, and rodents. Tests were performed with nanoformulated rilpivirine (NRPV), a non-nucleoside reverse transcriptase inhibitor (NNRTI) used clinically to suppress or prevent HIV-1 infection. First, CD4+ T cells and monocyte-derived macrophages were EuS-treated with and without endocytic blockers to identify …

Interplay Between Mirnas And Lncrnas: Mode Of Action And Biological Roles In Plant Development And Stress Adaptation, Xianxiang Meng, Aixia Li, Bin Yu, Shengjun Li

School of Biological Sciences: Faculty Publications

Plants employ sophisticated mechanisms to control developmental processes and to cope with environmental changes at transcriptional and post-transcriptional levels. MicroRNAs (miRNAs) and long noncoding RNAs (lncRNAs), two classes of endogenous noncoding RNAs, are key regulators of gene expression in plants. Recent studies have identified the interplay between miRNAs and lncRNAs as a novel regulatory layer of gene expression in plants. On one hand, miRNAs target lncRNAs for the production of phased small interfering RNAs (phasiRNAs). On the other hand, lncRNAs serve as origin of miRNAs or regulate the accumulation or activity of miRNAs at transcription and post-transcriptional levels. Theses lncRNA …

Origin Of Agricultural Plant Pathogens: Diversity And Pathogenicity Of Rhizoctonia Fungi Associated With Native Prairie Grasses In The Sandhills Of Nebraska, Srikanth Kodati, Anthony O. Adesemoye, Gary Y. Yuen, Jerry Volesky, Sydney E. Everhart

Department of Plant Pathology: Faculty Publications

The Sandhills of Nebraska is a complex ecosystem, covering 50,000 km² in central and western Nebraska and predominantly of virgin grassland. Grasslands are the most widespread vegetation in the U.S. and once dominated regions are currently cultivated croplands, so it stands to reason that some of the current plant pathogens of cultivated crops originated from grasslands, particularly soilborne plant pathogens. The anamorphic genus Rhizoctonia includes genetically diverse organisms that are known to be necrotrophic fungal pathogens, saprophytes, mycorrhiza of orchids, and biocontrol agents. This study aimed to evaluate the diversity of Rhizoctonia spp. on four native grasses in the …

A High-Androgen Microenvironment Inhibits Granulosa Cell Proliferation And Alters Cell Identity, Renee M. Mcfee, Sarah M. Romereim, Alexandria P. Snider, Adam F. Summers, William E. Pohlmeier, Scott G. Kurz, Robert A. Cushman, John S. Davis, Jennifer R. Wood, Andrea S. Cupp

School of Veterinary and Biomedical Sciences: Faculty Publications

A naturally occurring bovine model with excess follicular fluid androstenedione (High A4), reduced fertility, and polycystic ovary syndrome (PCOS)-like characteristics has been identified. We hypothesized High A4 granulosa cells (GCs) would exhibit altered cell proliferation and/or steroidogenesis. Microarrays of Control and High A4 GCs combined with Ingenuity Pathway Analysis indicated that High A4 GCs had cell cycle inhibition and increased expression of microRNAs that inhibit cell cycle genes. Granulosa cell culture confirmed that A4 treatment decreased GC proliferation, increased anti-Müllerian hormone, and increased mRNA for CTNNBIP1. Increased CTNNBIP1 prevents CTNNB1 from interacting with members of the WNT signaling pathway thereby …

Early Satellite Cell Communication Creates A Permissive Environment For Long-Term Muscle Growth, Kevin A. Murach, Bailey D. Peck, Robert A. Policastro, Ivan J. Vechetti, Douglas W. Van Pelt, Cory M. Dungan, Lance T. Denes, Xu Fu, Camille R. Brightwell, Gabriel E. Zentner, Esther E. Dupont-Versteegden, Christopher I. Richards, Jeramiah J. Smith, Christopher S. Fry, John J. Mccarthy, Charlotte A. Peterson

Department of Nutrition and Health Sciences: Faculty Publications

Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking, satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show satellite cells communicate with other cells in skeletal muscle during mechanical overload. Early satellite cell EV communication primes the muscle milieu for proper long-term extracellular matrix (ECM) deposition and is sufficient to support sustained hypertrophy in adult mice, even in the absence of fusion to muscle fibers. Satellite cells modulate chemokine gene expression across cell types within the first few days of loading, and EV delivery of miR 206 to fibrogenic cells represses Wisp1 expression …

Phenotypic Plasticity Of Diverse Sorghum Varieties In Response To Nitrogen Deficit Stress, Mackenzie Zwiener

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

The movement of nutrients from old vegetative tissue to young leaves and reproductive organs is known as senescence. Senescence can be influenced by the environment of a plant, such as, drought, heat, and nutrient stress. These environmental stressors can also influence canopy architecture. Crop canopy consists of several traits including: leaf number, angle, length and width. Past research in crops like maize and rice have shown significant influences of more erect leaves, including, the ability for increased planting density, which optimizes light interception and increases yield. In a field trial of a sorghum association panel including 345 different sorghum varieties …

Quantification Of The Mincer Et Al. 1993 Method Of Age Estimation For The Purpose Of Increasing The Reliability And Accuracy Of Scores Within The System, Bailey Oettel

Department of Anthropology: Theses and Student Research

There is currently a need to test new methods of increasing the accuracy and reliability of the stages scored by users of subjective methodologies within the forensic sciences. One way this can be done is through the quantification of these subjective stages through metric measurements and the application of sectioning points. This research assesses the quantification of the subjective stages within the Mincer et al. (1993) method of age estimation through odontometric measurements and the application of sectioning points. In this study, five odontometric measurements taken from radiographs of fifty-five third mandibular molars from thirty-nine individuals were used to establish …

Saturated Free Fatty Acids Induce Placental Trophoblast Lipoapoptosis, Sathish Kumar Natarajan, Taylor Bruett, Philma Glora Muthuraj, Prakash K. Sahoo, Jillian Power, Justin L. Mott, Corrine Hanson, Ann Anderson-Berry

Department of Nutrition and Health Sciences: Faculty Publications

Obesity during pregnancy increases the risk for maternal complications like gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also increases the risk of childhood obesity, intrauterine growth restriction (IUGR) and diabetes to the offspring. Increased circulating free fatty acids (FFAs) in obesity due to adipose tissue lipolysis induces lipoapoptosis to hepatocytes, cholangiocytes, and pancreatic-β-cells. During the third trimester of human pregnancy, there is an increase in maternal lipolysis and release of FFAs into the circulation. It is currently unknown if increased FFAs during gestation as a result of maternal obesity cause placental cell lipoapoptosis. Increased exposure of FFAs during maternal …

Crispr/Cas9-Induced Fad2 And Rod1 Mutations Stacked With Fae1 Confer High Oleic Acid Seed Oil In Pennycress (Thlaspi Arvense L.), Brice A. Jarvis, Trevor B. Romsdahl, Michaela G. Mcginn, Tara J. Nazarenus, Edgar B. Cahoon, Kent D. Chapman, John C. Sedbrook

Department of Biochemistry: Faculty Publications

Pennycress (Thlaspi arvense L.) is being domesticated as an oilseed cash cover crop to be grown in the off-season throughout temperate regions of the world. With its diploid genome and ease of directed mutagenesis using molecular approaches, pennycress seed oil composition can be rapidly tailored for a plethora of food, feed, oleochemical and fuel uses. Here, we utilized Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology to produce knockout mutations in the FATTY ACID DESATURASE2 (FAD2) and REDUCED OLEATE DESATURATION1 (ROD1) genes to increase oleic acid content. High oleic acid (18:1) oil is valued for its oxidative stability that is …

Process Interventions For Improving The Microbiological Safety Of Low Moisture Food Ingredients, Tushar Verma

Department of Food Science and Technology: Dissertations, Theses, and Student Research

The recurrence of Salmonella in low moisture foods and the implementation of the FSMA rule requires a need to validate legacy and novel processing technologies. In this dissertation, a legacy thermal (extrusion), a novel thermal (radiofrequency (RF) heating), and a non-thermal (chlorine dioxide) technology, were evaluated as intervention technologies for Salmonella in low moisture foods. The twin-screw extruder was performed at different levels of screw speeds, temperatures, moisture contents, and fat contents to understand the impact of processing conditions on Salmonella inactivation in oat flour. At temperature >65°C, the Salmonella population was below the detection limit. At 55°C, Salmonella reduction …

Microbial Challenge Studies Of Radio Frequency Heating For Dairy Powders And Gaseous Technologies For Spices, Xinyao Wei

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Persistence, thermal resistance, and survival of Salmonella in low moisture foods (LMF) have resulted in several foodborne illness outbreaks. Both existing and novel pasteurization technologies need to be validated for microbial safety of LMF. In this dissertation, a framework for using radio frequency (RF) heating to enhance microbial safety of milk powders and egg white powder was established. Thermal inactivation kinetics of Salmonella in milk powders were determined to guide the dairy industry for identifying thermal processing conditions for pasteurization. Storage time showed no effect on the thermal resistance of Salmonella, which can simplify the process validation study in …

Preclinical Development Of Single Walled Carbon Nanotube-Based Optical Biosensors, Eric M. Hofferber

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

High resolution, long-term monitoring of key biological analytes would improve patient outcomes by providing earlier detection of disease states and improved efficacy of treatment. One class of biosensors that have gained much attention in recent years are optical biosensors. Optical probes are attractive biosensors due to their noninvasive nature of detection, as certain light can pass through tissue, water, and blood. Single walled carbon nanotubes (SWNT) are a specific type of optical biosensor that fluoresce in the near infrared range of the electromagnetic spectrum and offer unparalleled spatial and temporal resolution. SWNT have been applied as biosensors in vitro, …

Surface Functionalization Of Elastomers For Tunable Crystal Growth And Smart Adhesives, John Kapitan

Department of Chemistry: Dissertations, Theses, and Student Research

Silicone rubbers have seen extensive work on modulation of their surface environments for use in microfluidics, cell adhesion, and sensing. Most surface procedures utilize a common initial step of oxidation of the surface to increase the number of active surface functional groups. Following oxidation more permanent functionalities can be imparted on the surface using silanization, grafting polymer brushes, or creating ionic bonds to the surface. Of these three, silanization proves to be the most pervasive due to the range of procedures available and how easy the procedures prove to be. However, the mechanism by which silanization is performed heavily involves …

Improving Accuracy Of Unmanned Aerial System Thermal Infrared Remote Sensing For Use In Energy Balance Models In Agriculture Applications, Mitchell S. Maguire, C.M.U. Neale, Wayne E. Woldt

Department of Mechanical and Materials Engineering: Faculty Publications

Unmanned aerial system (UAS) remote sensing has rapidly expanded in recent years, leading to the development of several multispectral and thermal infrared sensors suitable for UAS integration. Remotely sensed thermal infrared imagery has been used to detect crop water stress and manage irrigation by leveraging the increased thermal signatures of water stressed plants. Thermal infrared cameras suitable for UAS remote sensing are often uncooled microbolometers. This type of thermal camera is subject to inaccuracies not typically present in cooled thermal cameras. In addition, atmospheric interference also may present inaccuracies in measuring surface temperature. In this study, a UAS with integrated …

Informing Drought Mitigation Policy By Estimating The Value Of Water For Crop Production, Renata Rimsaite, Justin Gibson, Nicholas Brozovic

School of Natural Resources: Faculty Publications

Farmers use irrigation to mitigate drought risk and reduce yield uncertainty. A clear understanding of the monetary value of irrigation water and how it varies across time and space can help to inform farmers and policymakers about the potential impacts of water shortages and reduce uncertainty in decision making. Here, we introduce a framework for understanding the economic value of water used to produce corn in the central High Plains region during the period 2010–2017. Our analysis uses publicly available data for corn price and for irrigated and non-irrigated yields and incorporates irrigation requirement adjustments to account for the hydrologic …

Effects Of Farrowing Stall Layout And Number Of Heat Lamps On Sow And Piglet Behavior, Suzanne M. Leonard, Hongwei Xin, Tami M. Brown-Brandl, Brett C. Ramirez, Anna K. Johnson, Somak Dutta, Gary A. Rohrer

Department of Animal Science: Faculty Publications

Farrowing stalls are used in the United States swine industry to reduce pre-weaning piglet mortality, enable efficient individual animal management, and decrease facility construction and operating costs. The quantity and quality of space provided for sows and piglets in farrowing stalls are important economic and welfare considerations. To further explore the impacts of farrowing stall space allocation, a large-scale field study was conducted to compare sow and piglet behavior when housed in three farrowing stall layouts (TSL – traditional stall layout, ECSL – expanded creep area stall layout, ESCSL – expanded sow and creep area stall layout) with either one …

A Guide To Helminth Parasites Reported From Shorebirds (Charadriidae) From The Americas, Albert G. Canaris, Sofia Capasso, Gay J. Canaris

MANTER: Journal of Parasite Biodiversity

The shorebird family Charadriidae in the Americas consists of 21 native and 7 vagrant species. Members of the family occupy a diversity of open habitats, ranging from Arctic tundra during nesting, coastal sands, and mudflats to inland prairies, savannas, and wetlands. Some native plovers migrate from nesting grounds in North America to wintering grounds in South America (Hayman et al., 1986; Paulson, 2005; Winkler et al., 2020). Our search of the literature revealed the following: 17 of 28 host species infected with helminth parasites, 153 helminth species, and 199 infections involving 13 geographic areas. The purpose of this guide is …

Non-Nutritive Suck Burst Pattern Stability In Extremely Premature Infants, Alejandra Marquez

College of Education and Human Sciences: Dissertations, Theses, and Student Research

The development of non-nutritive suck (NNS) burst dynamics in preterm infants reflects the integrity of the brain and is used clinically to assess feeding readiness and orofacial motor development (Mizuno and Ueda, 2005). The application of NNS analytics in the present report represents one outcome measurement set that is part of an ongoing clinical trial involving extremely preterm infants (EPI’s,[GA]) randomized to receive either pulsed orocutaneous stimulation therapeutics or a sham (blind pacifier), in conjunction with salivary sampling twice weekly to map gene expression of key proteins involved in neural development and molecular sensing of feeding related pathways in the …

An Ancient, Light-Dependent Hydrocarbon-Forming Enzyme, Ananya Mukherjee

Center for Plant Science Innovation: Faculty Publications

No abstract provided.

Recovery Method For Mites Discovered In Mummified Human Tissue, Jessica Smith

Department of Anthropology: Theses and Student Research

Much like other arthropods, mites have been discovered in a wide variety of forensic and archaeological contexts featuring mummified remains. Their accurate identification has assisted forensic scientists and archaeologists in determining environmental, depositional, and taphonomic conditions that surrounded the mummified remains after death. Consequently, their close association with cadavers has led some researchers to intermittently advocate for the inclusion of mites in archaeological site analyses and forensic case studies. However, despite their potential value, mites have been underutilized with a variety of reasons for the lack of inclusion of mites in archaeological and forensic analyses. Chief amongst these reasons is …

A High-Androgen Microenvironment Inhibits Granulosa Cell Proliferation And Alters Cell Identity, Renee Mcfee Fee, Sarah Romereim, Alexandria P. Snider, Adam F. Summers, William E. Pohlmeier, Scott G. Kurz, Robert A. Cushman, John S. Davis, Jennifer R. Wood, Andrea S. Cupp

Department of Animal Science: Faculty Publications

A naturally occurring bovine model with excess follicular fluid androstenedione (High A4), reduced fertility, and polycystic ovary syndrome (PCOS)-like characteristics has been identified. We hypothesized High A4 granulosa cells (GCs) would exhibit altered cell proliferation and/or steroidogenesis. Microarrays of Control and High A4 GCs combined with Ingenuity Pathway Analysis indicated that High A4 GCs had cell cycle inhibition and increased expression of microRNAs that inhibit cell cycle genes. Granulosa cell culture confirmed that A4 treatment decreased GC proliferation, increased anti-Müllerian hormone, and increased mRNA for CTNNBIP1. Increased CTNNBIP1 prevents CTNNB1 from interacting with members of the WNT signaling pathway thereby …

Late-Seeded Cover Crops In A Semiarid Environment: Overyielding, Dominance And Subsequent Crop Yield, John R. Hendrickson, Mark A. Liebig, David W. Archer, Marty Schmer, Kristine A. Nichols, Donald L. Tanaka

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Interest in cover crops is increasing but information is limited on integrating them into crop rotations especially in the relatively short growing season on the northern Great Plains. A 3-yr research project, initiated in 2009 near Mandan, North Dakota, USA, evaluated (1) what impact cover crops may have on subsequent cash crops yields and (2) whether cover crop mixtures are more productive and provide additional benefits compared to cover crop monocultures. The study evaluated 18 different cover crop monocultures and mixtures that were seeded in August following dry pea (Pisum sativum L.). The following year, spring wheat (Triticum aestivum L.), …

Removal Of Carbamazepine Onto Modified Zeolitic Tuff In Different Water Matrices: Batch And Continuous Flow Experiments, Othman A. Al-Mashaqbeh, Diya A. Alsafadi, Layal Z. Alsalhi, Shannon L. Bartelt-Hunt, Daniel D. Snow

Nebraska Water Center: Faculty Publications

Carbamazepine (CBZ) is the most frequently detected pharmaceutical residues in aquatic environments effluent by wastewater treatment plants. Batch and column experiments were conducted to evaluate the removal of CBZ from ultra-pure water and wastewater treatment plant (WWTP) effluent using raw zeolitic tuff (RZT) and surfactant modified zeolite (SMZ). Point zero net charge (pHpzc), X-ray diffraction (XRD), X-ray fluorescence (XRF), and Fourier Transform Infrared (FTIR) were investigated for adsorbents to evaluate the physiochemical changes resulted from the modification process using Hexadecyltrimethylammonium bromide (HDTMA-Br). XRD and FTIR showed that the surfactant modification of RZT has created an amorphous surface with new alkyl …

Microfluidic-Based Bacterial Molecular Computing On A Chip, Daniel P. Martins, Michael Taynnan Barros, Benjamin O'Sullivan, Ian Seymour, Alan O'Riordan, Lee Coffey, Joseph Sweeney, Sasitharan Balasubramaniam,

School of Computing: Faculty Publications

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and electrochemical sensing technologies. The computing can be flexibly integrated into the chip, but we focus on engineered bacterial AND Boolean logic gate and ON-OFF switch sensors that produces secondary signals to change the pH and dissolved oxygen concentrations. We present a prototype with experimental results that shows the electrochemical sensors can detect small pH and dissolved oxygen concentration changes created by the engineered bacterial populations’ …

Changes In Subcellular Localization Of Host Proteins Induced By Plant Viruses, Rosalba Rodriguez-Pena, Kaoutar El Mounadi, Hernan Garcia-Ruiz

Department of Plant Pathology: Faculty Publications

Viruses are dependent on host factors at all parts of the infection cycle, such as translation, genome replication, encapsidation, and cell-to-cell and systemic movement. RNA viruses replicate their genome in compartments associated with the endoplasmic reticulum, chloroplasts, and mitochondria or peroxisome membranes. In contrast, DNA viruses replicate in the nucleus. Viral infection causes changes in plant gene expression and in the subcellular localization of some host proteins. These changes may support or inhibit virus accumulation and spread. Here, we review host proteins that change their subcellular localization in the presence of a plant virus. The most frequent change is the …

An Analysis Of The Behaviors Used By Physicians And (Pre)Medical Students To Cope With Stress, Carter Bracht

Honors Program: Senior Projects (Public)

Physicians (both practicing and resident) in the U.S. are experiencing high rates of burnout and mental health issues because of the stressors related to their career and the lack of coping mechanisms in practice by these physicians. As a population, physicians normalize internalization of their stress as members of a “proud” community. This study sought to examine the positive, negative, and positive addiction coping mechanisms that physicians use to relieve job-related stress using the following coping domains: emotion-oriented, task-oriented, and avoidance-oriented coping. We further sought to examine stressors and coping mechanisms that are introduced in (pre)medical school and how they …

Wimmin In The Mass Media, Terry Nygren, Mary Jo Deegan

Zea E-Books Collection

Introduction to the 40th Anniversary Edition: Wimmin in the Mass Media and Centennial College, Looking Backwards • Mary Jo Deegan

WIMMIN IN THE MASS MEDIA: Articles Collected at the Centennial Education Program, Fall 1980

Introduction: Wimmin and the Mass Media — Construction of the Self • Mary Jo Deegan and Terry Nygren

Examining the Top Ten, or Why Those Songs Make the Charts • Jane Pemberton

Images of Women in Rock Music: Analysis of B-52’s and Black Rose• Sheila M. Krueger

Women in Sitcoms: “I Love Lucy”• Nancy Grant-Colson

Horatio Alger is Alive and Well and Masquerading as a Feminist, …

Modern Silicon Dynamics Of A Small High-Latitude Subarctic Lake, Petra Zahajska, Carolina Olid, Johanna Stadmark, Sherilyn C. Fritz, Sophie Opfergelt, Daniel J. Conley

Department of Earth and Atmospheric Sciences: Faculty Publications

High biogenic silica (BSi) concentrations occur sporadically in lake sediments throughout the world; however, the processes leading to high BSi concentrations vary. We explored the factors responsible for the high BSi concentration in sediments of a small, high-latitude subarctic lake (Lake 850). The Si budget of this lake had not been fully characterized before to establish the drivers of BSi accumulation in this environment. To do this, we combined measurements of variations in stream discharge, dissolved silica (DSi) concentrations, and stable Si isotopes in both lake and stream water with measurements of BSi content in lake sediments. Water, radon, and …

Nozzle Selection And Adjuvant Impact On The Efficacy Of Glyphosate And Ppo-Inhibiting Herbicide Tank-Mixtures, Jesaelen G. Moraes, Thomas R. Butts, Vitor M. Anunciato, Joe D. Luck, Wesley C. Hoffmann, Ulisses R. Antuniassi, Greg R. Kruger

Department of Agronomy and Horticulture: Faculty Publications

PPO-inhibiting herbicides in combination with glyphosate for postemergence applications is a common approach to manage glyphosate- and ALS-inhibitor-resistant weeds. PPO-inhibitors can reduce glyphosate translocation when applied in tank-mixtures, but adjuvants may be used to overcome this effect. Additionally, optimal droplet size may be affected by tank-mixtures of different herbicides and it can be crucial to herbicide efficacy. Field and greenhouse studies were conducted to investigate the impact of nozzle selection and adjuvants on weed control and interactions when applying PPO-inhibitors (fomesafen or lactofen) alone or in tank-mixture with glyphosate to five weed species using six nozzle types. Ultra-coarse droplets were …

Implementing A Registry Federation For Materials Science Data Discovery, Raymond L. Plante, Chandler A. Becker, Andrea Medina-Smith, Kevin Brady, Alden Dima, Benjamin Long, Laura M. Bartolo, James A. Warren, Robert J. Hanisch

Copyright, Fair Use, Scholarly Communication, etc.

As a result of a number of national initiatives, we are seeing rapid growth in the data important to materials science that are available over the web. Consequently, it is becoming increasingly difficult for researchers to learn what data are available and how to access them. To address this problem, the Research Data Alliance (RDA) Working Group for International Materials Science Registries (IMRR) was established to bring together materials science and information technology experts to develop an international federation of registries that can be used for global discovery of data resources for materials science. A resource registry collects high-level metadata …