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August 2013 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Rcytoscape: Tools For Exploratory Network Analysis, Paul Shannon, Mark L. Grimes, Burak Kutlu, Jan J. Bit, David J. Galas

Biological Sciences Faculty Publications

Background: Biomolecular pathways and networks are dynamic and complex, and the perturbations to them which cause disease are often multiple, heterogeneous and contingent. Pathway and network visualizations, rendered on a computer or published on paper, however, tend to be static, lacking in detail, and ill-equipped to explore the variety and quantities of data available today, and the complex causes we seek to understand.

Results: RCytoscape integrates R (an open-ended programming environment rich in statistical power and datahandling facilities) and Cytoscape (powerful network visualization and analysis software). RCytoscape extends Cytoscape's functionality beyond what is possible with the Cytoscape graphical user interface. …

An Inverted Repeat In The Ospc Operator Is Required For Induction In Borrelia Burgdorferi, Dan Drecktrah, Laura S. Hall, Laura L. Hoon-Hanks, D. Scott Samuels

Biological Sciences Faculty Publications

Borrelia burgdorferi, the spirochete that causes Lyme disease, differentially regulates synthesis of the outer membrane lipoprotein OspC to infect its host. OspC is required to establish infection but then repressed in the mammal to avoid clearance by the adaptive immune response. Inverted repeats (IR) upstream of the promoter have been implicated as an operator to regulate ospC expression. We molecularly dissected the distal inverted repeat (dIR) of the ospC operator by site-directed mutagenesis at its endogenous location on the circular plasmid cp26. We found that disrupting the dIR but maintaining the proximal IR prevented induction of OspC synthesis by …

Analgesic Effect Of A Mixed T-Type Channel Inhibitor/Cb2 Receptor Agonist, Vinicius M. Gadotti, Haitao You, Ravil R. Petrov, N. Daniel Berger, Philippe Diaz, Gerald W. Zamponi

Biomedical and Pharmaceutical Sciences Faculty Publications

Background: Cannabinoid receptors and T-type calcium channels are potential targets for treating pain. Here we report on the design, synthesis and analgesic properties of a new mixed cannabinoid/T-type channel ligand, NMP-181. Results: NMP-181 action on CB1 and CB2 receptors was characterized in radioligand binding and in vitro GTP gamma[S-35] functional assays, and block of transiently expressed human Cav3.2 T-type channels by NMP-181 was analyzed by patch clamp. The analgesic effects and in vivo mechanism of action of NMP-181 delivered spinally or systemically were analyzed in formalin and CFA mouse models of pain. NMP-181 inhibited peak Ca(V)3.2 currents with IC50 values …

Camas, Summer 2013

Camas

Waiting / Rick Bass -- The Cakewalk / Jenner Harsha -- Nurse Log / Mark Rozema -- Water Contours / Denise Fisher -- Oil Baby / Carl Corder -- Coming to Rest / Emily Strauss -- Lines on the Land / Emily Strauss -- What We Talk About When We Talk About the Weather / Matthew Burns -- Such Grim Seasons / Mercedes Lawry -- 279 / Clark Chatlain -- 316 / Clark Chatlain -- Benchmark / Jolie B. Kaytes -- Scratch Gravel / Kira Knoles

Starvation-Associated Genome Restructuring Can Lead To Reproductive Isolation In Yeast, Evgueny Kroll, Scott Coyle, Barbara Dunn, Gregory Koniges, Anthony Aragon, Jeremy Edwards, Frank Rosenzweig

Biological Sciences Faculty Publications

Knowledge of the mechanisms that lead to reproductive isolation is essential for understanding population structure and speciation. While several models have been advanced to explain post-mating reproductive isolation, experimental data supporting most are indirect. Laboratory investigations of this phenomenon are typically carried out under benign conditions, which result in low rates of genetic change unlikely to initiate reproductive isolation. Previously, we described an experimental system using the yeast Saccharomyces cerevisiae where starvation served as a proxy to any stress that decreases reproduction and/or survivorship. We showed that novel lineages with restructured genomes quickly emerged in starved populations, and that these …

Research View, Summer 2013

Research View

Contents of this issue include:

The Air We Breathe: UM researcher finds young brains harmed by urban air pollution

Quick Looks: Study of Mealybug Bacteria Reveals Secrets of Symbiosis -- Award to Study Hospital Discharge Process in Rural Areas -- Autism Waiver Program Shows Promising Results -- Paper Details Stressors Faced by Sexual Minority Vets -- Innovation and Imagination: Events Highlight Research and Scholarship

There's an App for That: Researchers develop modern tool to measure heat stress in humans

Warring With Words: Religion scholar chases text destruction in the ancient world

July 2013 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Understanding Relationships Among Abundance, Extirpation, And Climate At Ecoregional Scales, Erik A. Beever, Solomon Z. Dobrowski, J. Long, A. R. Mynsberge, N. B. Piekielek

Forest Management Faculty Publications

Recent research on mountain-dwelling species has illustrated changes in species' distributional patterns in response to climate change. Abundance of a species will likely provide an earlier warning indicator of change than will occupancy, yet relationships between abundance and climatic factors have received less attention. We tested whether predictors of counts of American pikas (Ochotona princeps) during surveys from the Great Basin region in 1994-1999 and 2003-2008 differed between the two periods. Additionally, we tested whether various modeled aspects of ecohydrology better predicted relative density than did average annual precipitation, and whether risk of site-wide extirpation predicted subsequent population counts of …

When A Woman Campaigns, Emily Sloan

Montana Law Review

This essay is a portion of a manuscript written by Montana's first female county attorney about her campaigns in the 1920s.

Teacher Learning In Lesson Study, Jennifer M. Lewis, Davida Fischman, Iris Riggs, Kelli Wasserman

The Mathematics Enthusiast

This article documents teacher learning through participation in lesson study, a form of professional development that originated in Japan and is currently practiced widely in the US. Specifically, the paper shows how teachers in three different lesson study teams 1) expanded their mathematical content knowledge, 2) grew more skillful at eliciting and analyzing student thinking, 3) became more curious about mathematics and about student thinking, 4) emphasized students’ autonomous problem‐solving, and 5) increasingly used multiple representations for solving mathematics problems. These outcomes were common across three lesson study teams, despite significant differences among the teams’ composition, leadership, and content foci.

Feedback To Support Learning In The Leadership Institute For Teachers, Cathy Kinzer, Janice Bradley, Patrick Morandi

The Mathematics Enthusiast

Feedback is a type of formative assessment used to inform instruction and advance learning. Feedback serves as a mechanism to connect teaching and learning at the student level. Learners receive feedback, formally or informally, as they engage in learning experiences. Within the Leadership Institute for Teachers, a National Science Foundation funded research project, we are exploring feedback as a research‐informed process to support learning and improvement for individuals, teams, and university courses. There is an explicit focus on creating a culture of critical thinking and reasoning, taking ownership for learning both individually and collectively, and understanding how to improve teaching …

Breed Locally, Disperse Globally: Fine-Scale Genetic Structure Despite Landscape-Scale Panmixia In A Fire-Specialist, Jennifer C. Pierson, Fred W. Allendorf, Pierre Drapeau, Michael K. Schwartz

Biological Sciences Faculty Publications

An exciting advance in the understanding of metapopulation dynamics has been the investigation of how populations respond to ephemeral patches that go 'extinct' during the lifetime of an individual. Previous research has shown that this scenario leads to genetic homogenization across large spatial scales. However, little is known about fine-scale genetic structuring or how this changes over time in ephemeral patches. We predicted that species that specialize on ephemeral habitats will delay dispersal to exploit natal habitat patches while resources are plentiful and thus display fine-scale structure. To investigate this idea, we evaluated the effect of frequent colonization of ephemeral …

Environment, Behavior And Physiology: Do Birds Use Barometric Pressure To Predict Storms?, Creagh W. Breuner, Rachel Seabury Sprague, Stephen Harold Patterson, H. Arthur Woods

Biological Sciences Faculty Publications

Severe storms can pose a grave challenge to the temperature and energy homeostasis of small endothermic vertebrates. Storms are accompanied by lower temperatures and wind, increasing metabolic expenditure, and can inhibit foraging, thereby limiting energy intake. To avoid these potential problems, most endotherms have mechanisms for offsetting the energetic risks posed by storms. One possibility is to use cues to predict oncoming storms and to alter physiology and behavior in ways that make survival more likely. Barometric pressure declines predictably before inclement weather, and several lines of evidence indicate that animals alter behavior based on changes in ambient pressure. Here …

Effects Of Experimentally Elevated Traffic Noise On Nestling White-Crowned Sparrow Stress Physiology, Immune Function And Life History, Ondi L. Crino, Erin E. Johnson, Jessica L. Blickley, Gail L. Patricelli, Creagh W. Breuner

Biological Sciences Faculty Publications

Roads have been associated with behavioral and physiological changes in wildlife. In birds, roads decrease reproductive success and biodiversity and increase physiological stress. Although the consequences of roads on individuals and communities have been well described, the mechanisms through which roads affect birds remain largely unexplored. Here, we examine one mechanism through which roads could affect birds: traffic noise. We exposed nestling mountain white-crowned sparrows (Zonotrichia leucophrys oriantha) to experimentally elevated traffic noise for 5 days during the nestling period. Following exposure to traffic noise we measured nestling stress physiology, immune function, body size, condition and survival. Based …

The New Wave Of Florida Energy: The Regulatory Path To Harnessing Marine Hydrokinetic Power, Andrew Thornquest

Public Land & Resources Law Review

No abstract provided.

Biob 171n.01: Principles Of Biological Diversity Lab, Gregory Peters

University of Montana Course Syllabi

No abstract provided.

Biob 170n.01: Principles Of Biological Diversity, Gregory Peters

University of Montana Course Syllabi

No abstract provided.

June 2013 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Three-Dimensional, High-Resolution Skeletal Kinematics Of The Avian Wing And Shoulder During Ascending Flapping Flight And Uphill Flap-Running, David B. Baier, Stephen M. Gatesy, Kenneth P. Dial

Biological Sciences Faculty Publications

Past studies have shown that birds use their wings not only for flight, but also when ascending steep inclines. Uphill flap-running or wing-assisted incline running (WAIR) is used by both flight-incapable fledglings and flight-capable adults to retreat to an elevated refuge. Despite the broadly varying direction of travel during WAIR, level, and descending flight, recent studies have found that the basic wing path remains relatively invariant with reference to gravity. If so, joints undergo disparate motions to maintain a consistent wing path during those specific flapping modes. The underlying skeletal motions, however, are masked by feathers and skin. To improve …

Humans Strengthen Bottom-Up Effects And Weaken Trophic Cascades In A Terrestrial Food Web, Tyler B. Muhly, Mark Hebblewhite, Dale Paton, Justin A. Pitt, Mark S. Boyce, Marco Musiani

Wildlife Biology Faculty Publications

Ongoing debate about whether food webs are primarily regulated by predators or by primary plant productivity, cast as top-down and bottom-up effects, respectively, may becoming superfluous. Given that most of the world's ecosystems are human dominated we broadened this dichotomy by considering human effects in a terrestrial food-web. We studied a multiple human-use landscape in southwest Alberta, Canada, as opposed to protected areas where previous terrestrial food-web studies have been conducted. We used structural equation models (SEMs) to assess the strength and direction of relationships between the density and distribution of: (1) humans, measured using a density index; (2) wolves …

Montana Kaimin, May 3, 2013, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Montana Kaimin, May 2, 2013, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

The Early Dissemination Defect Attributed To Disruption Of Decorin-Binding Proteins Is Abolished In Chronic Murine Lyme Borreliosis, Denise M. Imai, D. Scott Samuels, Sunlian Feng, Emir Hodzic, Kim Olsen, Stephen W. Barthold

Biological Sciences Faculty Publications

The laboratory mouse model of Lyme disease has revealed that Borrelia burgdorferi differentially expresses numerous outer surface proteins that influence different stages of infection (tick-borne transmission, tissue colonization, dissemination, persistence, and tick acquisition). Deletion of two such outer surface proteins, decorin-binding proteins A and B (DbpA/B), has been documented to decrease infectivity, impede early dissemination, and, possibly, prevent persistence. In this study, DbpA/B-deficient spirochetes were confirmed to exhibit an early dissemination defect in immunocompetent, but not immunodeficient, mice, and the defect was found to resolve with chronicity. Development of disease (arthritis and carditis) was attenuated only in the early stage …

A Field Experiment Demonstrating Plant Life-History Evolution And Its Eco-Evolutionary Feedback To Seed Predator Populations, Anurag A. Agrawal, Marc T. J. Johnson, Amy P. Hastings, John L. Maron

Biological Sciences Faculty Publications

The extent to which evolutionary change occurs in a predictable manner under field conditions and how evolutionary changes feed back to influence ecological dynamics are fundamental, yet unresolved, questions. To address these issues, we established eight replicate populations of native common evening primrose (Oenothera biennis). Each population was planted with 18 genotypes in identical frequency. By tracking genotype frequencies with microsatellite DNA markers over the subsequent three years (up to three generations, approximate to 5,000 genotyped plants), we show rapid and consistent evolution of two heritable plant life-history traits (shorter life span and later flowering time). This rapid evolution was …

Ski Joring Races: 2013, Christine Oschell

Institute for Tourism and Recreation Research Publications

The purpose of this study was to provide the organizers of the Whitefish Ski Joring Races with an understanding of their attendees and the total money spent in the area by those surveyed (Kalispell or Whitefish). The population of interest was participants and attendees of the 2013 Montana Ski Joring Races. Surveys were completed on-site.

Documents From The May 1, 2013 Meeting Of The Associated Students Of The University Of Montana (Asum), University Of Montana--Missoula. Associated Students

Senate Meeting Agendas and Minutes, 2007-Present

Agenda and meeting minutes from the May 1, 2013 meeting of the Associated Students of the University of Montana (ASUM). The following resolutions were decided at this meeting:

SB82-12/13: University of Montana Funding Shortfall

SB87-12/13: Amending Bylaws

SB88-12/13: Recognition

SB89-12/13: Student Instructional Equipment Fee Funds (SIEF)

SB91-12/13: University of Montana Health and Human Performance Policy

SB92-12/13: Personnel Policy

SB93-12/13: Residence Life Student Conduct Policies

SB94-12/13: Residence Life Communications

Montana Kaimin, April 25, 2013, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Montana Kaimin, April 24, 2013, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Documents From The April 24, 2013 Meeting Of The Associated Students Of The University Of Montana (Asum), University Of Montana--Missoula. Associated Students

Senate Meeting Agendas and Minutes, 2007-Present

Agenda and meeting minutes from the April 24, 2013 meeting of the Associated Students of the University of Montana (ASUM). The following resolutions were decided at this meeting:

SB80-12/13: Financial Aid

SB85-12/13: Amending House Rules