Digital Commons Network^™

Covalent Modification Of Recombinant Protein With Reactive Thiols, Sawyer Dulaney, Bailey Taylor

Honors Theses

Many diseases cause chronic and painful inflammation in different body systems. One of the front-line drug classes to treat such inflammation is Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Despite the benefits of oral administration of NSAIDs, there are drawbacks to their long-term usage because they can cause detrimental effects on off-target systems in the body such as the liver, kidney, or the lining of the intestinal tract. An alternative to NSAIDs is the usage of hydrogels for targeted drug delivery. Hydrogels can provide drug delivery in a specific portion of the site of inflammation, thus allowing higher doses of medication to be …

Optimization Of A Fluidized Bed Reactor For The Production Of Styrene From Ethylbenzene, Gregory Espenan

Honors Theses

In order to optimize Unit 500, a styrene production plant, the Net Present Value (NPV) was used as the objective function to ensure every optimization strategy had a positive economic effect. To optimize a chemical plant, it is important to note efficiency, economics, product specifications, and production requirements. The goal of this project was to make changes to the base case of Unit 500 to minimize the cost to produce styrene for an upstream unit. PRO/II was used to simulate various points in different unit operations throughout the process. The NPV was measured after each unit operation was simulated to …

Discovering More In Pharmacy - Journey To Commencement, Whitney Tarpy

Journey to Commencement

Katie Kreusel flourishing in research experiences.

Pre-Practice Hydration Status Of Collegiate Male American Football Players With Sickle Cell Trait, Sara Hoffman

Honors Theses

Since 2000, 63% of deaths associated with college football were due to complications, such as sickling events; however, sickle cell trait (SCT) only affects 3-4% of participating athletes. Sickling events can be exasperated by conditions, including heat exposure, dehydration, and intense physical activity and lead to rhabdomyolysis and death. Assessing hydration status is crucial for athletes and the use of urine specific gravity (USG) has been shown to provide rapid and valid results. The purpose of this study was to assess the prevalence of dehydration among SCT carrying American college football players.

Division I collegiate football athletes participated as part …

Comprehensive Analysis Of Financial Accounting Through Series Of Case Studies, Tyler Anderson Burke

Honors Theses

This thesis is a collection of eleven case studies that were compiled during the 2020-2021 school year. The cases studies focus on a variety of topics concerning the field of accountancy. Over a period of two semesters, the cases were researched and written independently and in a group setting. The cases studies that were written with my fellow group members resulted in a group case competition at the end of the course. This thesis was developed under the guidance of Victoria Dickinson, Ph.D., CPA.

Case Studies In Accountancy, Michael Keene

Honors Theses

Case Studies in Accountancy is a compilation of case studies completed in fulfillment of ACCY 420. My cases are titled as followed: A Tale of Two Cities, Financial Statements, Presidential Debate, Tax Cuts and Job Act and Taxodus, Professional Interview, Financial Crisis, Case Competition Amazon Overview, Case Competition Amazon Audit Analyst, Case Competition Amazon Tax Advisor, Case Competition Amazon Advisory Consultant and Case Competition Amazon’s Equity Position. These cases covered a variety of topics in the world of accountancy as well as touching on our personal lives. In the first semester of the course, cases were typically individual before moving …

Computational And Spectroscopic Studies Of New Sulfur-Containing Dipole-Bound Anions, Nicholas Allen Kruse

Honors Theses

Sulfur and Nitrogen are essential ingredients in both life-supporting and light-harvesting molecules. Their presence also usually leads to the delocalization of electrons and large dipole and quadrupole moments. Such molecules are sometimes able to form negative ions through the electrostatic binding of an excess electron. These so-called multipole-bound (dipole-bound, quadrupole-bound, etc.) anions have been shown to be important in radiation damage in biology and electron transport processes. Here, we present our recent computational and experimental results studying the creation of new multipole-bound anions.

Rising From The Ashes: An Analysis Of How One Infamous Promotional Event Caused A Company's Ruin And A Concept On The Future Of Influencer Experiences, Janis B. Kruger

Honors Theses

This thesis and its research focuses on the topic of modern influencer marketing through digital media. Throughout the thesis, traditional marketing tactics and the power of influence is discussed, and then it moves into the topic of modern advertising and the role that modern social media influencers play in reaching the consumer. The methodology behind influencer marketing is explained and consumer behavior is analyzed. The 2017 Fyre Festival promotional event is then used as an example to dissect this marketing tactic and how the event impacted the future of influencer marketing. Finally, a modern-day, hypothetical campaign based on the concept …

The Role Of Ionic Liquids In Gold Nanorod Synthesis, Noah Grovich

Honors Theses

The term cancer is used to define a large set of medical conditions that result from uncontrolled cell proliferation. The severity of cancer ranges depending on several factors, but it is one of the leading causes of death in approximately 60% of the world. Current treatment options are often not efficacious and face many limitations especially regarding limiting the secondary damage to healthy cells. Gold nanorods have shown to be a potential solution for effectively overcoming many of these barriers, but their employment is limited due to toxicity concerns stemming from the use of hexadecyltrimethylammonium bromide (CTAB) in their synthesis. …

Probing Myosin Ensemble Mechanics In Actin Filament Bundles Using Optical Tweezers, Omayma Alazzam, Janie Watts, Dana N. Reinemann

Faculty and Student Publications

Myosins are motor proteins that hydrolyze ATP to step along actin filament (AF) tracks and are essential in cellular processes such as motility and muscle contraction. To understand their force-generating mechanisms, myosin II has been investigated both at the single-molecule (SM) level and as teams of motors in vitro using biophysical methods such as optical trapping. These studies showed that myosin force-generating behavior can differ greatly when moving from the single-molecule level in a three-bead arrangement to groups of motors working together on a rigid bead or coverslip surface in a gliding arrangement. However, these assay constructions do not permit …

Comparative Analysis And Dynamic Response Of Abs Under Uv Light Degradation Using Shock Tube, Greer Lauber

Honors Theses

The purpose of this study was to examine the dynamic response of acrylonitrile-butadlene-styrene (ABS) when exposed to UV light. Impact-Resistant Easy-to-Form ABS sheets were tested using a Shock Tube. Three samples were tested at no UV light exposure and three were tested after 15 days of being exposed to rapid UV degradation rays. All samples were tested at a shock wave equivalent to 400 psi. The results showed that the UV damaged samples experienced a decrease in strength and energy absorption in comparison to the non-UV damaged samples. The average peak load for the non-UV degraded was 1261.89 Newtons and …

What Is The Satisfaction Of Youth Participating In A Pilot Reading And Food-Based Stem Education Program In Rural Appalachian Mississippi?, Meagan Smith

Honors Theses

Science, technology, engineering, and mathematics (STEM) education is a vital subsection of primary education which focuses on imparting knowledge to foster STEM literacy and ultimately bolster the workforce of STEM related fields (Holmlund, 2018). Due to both geographic and socioeconomic challenges, STEM education in rural areas suffers from a lack of engaging learning opportunities and contributes to a shortage of STEM professionals originating from rural areas (Munn, 2019)(Murphy, 2020). Rural areas such as Calhoun County, MS, where the pilot program associated with this thesis was conducted, do not have the means to support interactive learning institutions such as aquariums and …

Evaluating The Barriers Of Entry That Small Commercial Farmers Face And The Implications Of Such Barriers On Rural Communities, Lauren C. Chandler

Honors Theses

The research proposed in this thesis will identify the barriers of entry that

small farmers face when entering the Agricultural Industry. The proposed research will also seek to discover how having these barriers in place affects rural communities. This thesis conducts a literature review of the topic, sets the context for the research to be done, and proposes a research project to further investigate the topic. The proposed research will be done through administering a survey to stakeholders, and then interviewing a small sample of those surveyed to get a comprehensive look at the effects of agribusiness on rural communities. …

Employing A Public Policy Evaluative Framework: An Analysis Of Domestic Theme Park Development, Anthony Gray Houser

Honors Theses

The intention of the thesis is to examine the relationship between the development of the Walt Disney Company’s theme parks and public policy. Using the Disneyland Resort in Anaheim, California and the Walt Disney World Resort outside of Orlando, Florida as case studies, this thesis will execute a comparative analysis to better understand the relationship between the Walt Disney Company’s theme parks and public policy. Using an evaluative framework, this thesis will provide a deeper understanding of how public policy affected the development and the current operations of these theme parks. The driving research question in this thesis is, ‘what …

Breaking Boundaries And Making Her Way - Journey To Commencement, Lou Tyson

Journey to Commencement

Tayler Glover fosters opportunities for women in computer science.

Graduate Student Earns Summer Internship At Library Of Congress, Edwin B. Smith

University of Mississippi News

Roger Davis Jr. is among 42 selected for distinguished program

Deloitte, Foundation Endow $1.5m Um Accountancy Chair, Jonathan Scott

University of Mississippi News

Gift helps attract, retain top faculty to renowned program

A Quick Guide To The University's 169th Commencement, Staff Report

University of Mississippi News

Here's a rundown of schedules, parking, dining and livestreaming for graduation celebrations

Design Of An Implanted Vascular Access Device With A Mechanical Septum, Mallory Ann Moffett, Katherine Rose O'Quinn

Honors Theses

As populations continue to age, their need for medical care continues to rise. This is seen by the large need for implanted vascular devices (IVADs). IVADs are essential for individuals with poor venous access and patients requiring long-term venous delivered drugs. This document will explore the existing IVADs, where they fall short, and where our device, the IrisPort system, works to solve the unmet needs of patients. The IrisPort system is a needle-less port system that allows for repeated venous access without the use of a non-coring needle. Prior art searches have shown that the IrisPort is a novel solution …

First Test Of Lepton Flavor Universality In The Charmed Baryon Decays Ωc0 → Ω-ℓ+Νℓ Using Data Of The Belle Experiment, Y. B. Li, C. P. Shen, I. Adachi, H. Aihara, S. Al Said, D. M. Asner, H. Atmacan, T. Aushev, R. Ayad, V. Babu, S. Bahinipati, P. Behera, K. Belous, J. Bennett, F. Bernlochner, M. Bessner, B. Bhuyan, T. Bilka, A. Bobrov

Faculty and Student Publications

We present the first observation of the ωc0→ω-μ+νμ decay and present measurements of the branching fraction ratios of the ωc0→ω-ℓ+νℓ decays compared to the reference mode ωc0→ω-π+, (ℓ=e or μ). This analysis is based on 89.5 fb-1, 711 fb-1, and 121.1 fb-1 data samples collected with the Belle detector at the KEKB asymmetric-energy e+e- collider at the center-of-mass energies of 10.52 GeV, 10.58 GeV, and 10.86 GeV, respectively. The ωc0 signal yields are extracted by fitting Mωℓ and Mωπ spectra. The branching fraction ratios B(ωc0→ω-e+νe)/B(ωc0→ω-π+) and B(ωc0→ω-μ+νμ)/B(ωc0→ω-π+) are measured to be 1.98±0.13(stat)±0.08(syst) and 1.94±0.18(stat)±0.10(syst), respectively. The ratio of B(ωc0→ω-e+νe)/B(ωc0→ω-μ+νμ) is …

Molecular Dynamics Study Of Melting Behavior Of Planar Stacked Ti–Al Core–Shell Nanoparticles, Huadian Zhang, Yu Chen Su, Yiwei Han, Shan Jiang

Faculty and Student Publications

Selective laser sintering (SLS) is one of the most commonly used methods in additive manufacturing, due to its high prototyping speed and applicability to various materials. In the present work, molecular dynamics (MD) simulations were performed to study the thermodynamic behaviors of the planar stacked nanoparticles (NPs) model and explore the potential capability of the SLS process with nano-sized metal powders in the zero-gravity space environment. A multi-particle model of titanium–aluminum (Ti–Al) core–shell NP with a particle radius of 50 Å was constructed to investigate the characteristics of the melted pattern during sintering. Two patterns with different spatial densities were …

Search For Charged Lepton Flavor Violating Decays Of ϒ (1s), S. Patra, V. Bhardwaj, K. Trabelsi, I. Adachi, H. Aihara, S. Al Said, D. M. Asner, H. Atmacan, T. Aushev, R. Ayad, V. Babu, S. Bahinipati, P. Behera, K. Belous, J. Bennett, M. Bessner, B. Bhuyan, T. Bilka, A. Bobrov

Faculty and Student Publications

We present a search for the charged lepton-flavor-violating decays ϒ(1S) →ℓ±ℓ′∓ and radiative charged lepton-flavour-violating decays ϒ(1S) → γℓ±ℓ′∓ [ℓ,ℓ′ = e, μ, τ] using the 158 million ϒ(2S) sample collected by the Belle detector at the KEKB collider. This search uses ϒ(1S) mesons produced in ϒ(2S) → π+π− ϒ(1S) transitions. We do not find any significant signal, so we provide upper limits on the branching fractions at the 90% confidence level. [Figure not available: see fulltext.]

Sophomore Speech-Language Pathology Major Wins National Scholarship, Cameron Smith

University of Mississippi News

Amy-Kate Winter selected by National Student Speech Language Hearing Association

The Grate Solution: Simplifying Viking Oven Packaging Processes, Megan Jansen

Honors Theses

The following report details work completed to improve the Viking Oven Corporation’s gas oven assembly line. The current state of the line hosts an unreliable system for packaging oven grates. Viking manufactures two types of gas ovens on the same line: open burner and closed burner. These different types require different prepackaged grates to be included in the final assembly area. Viking estimates that the wrong grates are sent to the customer ten percent of the time. The following report presents research, brainstorming, problem-solving techniques, and proposed solutions to the problem. The proposed solution would solve the problem at little …

Peacock Remembered With Recovery Support Fund, Tina Hahn

University of Mississippi News

No abstract provided.

Senior Banking Major Selected As Orrin H. Swayze Scholar, Staff Report

University of Mississippi News

Wyatt Gunter chosen from five finalists for statewide honor

April 28, 2022, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Engineer's Research Charting New Waters In Fluid Studies, Edwin B. Smith

University of Mississippi News

Wen Wu receives EPSCoR grant to study applications of novel drag-reducing approach

A Molecular Dynamics Study Of The Laser Sintering Process And Subsequent Mechanical Properties Of Γ-Tial Nanoparticles, Eleanor Dickens

Honors Theses

Using molecular dynamics (MD) simulations, the laser sintering additive manufacturing process is investigated through the observation of γ-TiAl nanoparticles. This process is conducted using both uni-directional chain and stacking configurations. By mimicking the heating process and varying laser sintering parameters such as heating rater, sintering temperature, and particle orientation, the fusion behavior and resulting products are analyzed for both chain and stacking NP patterns. In of single chain cases, it is noticed that slower heating rates and higher melting temperatures yield larger neck growth between each individual particle and thus produce a more stable product. This leads to stronger mechanical …

Mark Loftin To Deliver Last Lecture Friday, Edwin B. Smith

University of Mississippi News

Retiring School of Applied Sciences associate dean to share reflections in Bryant Hall