Digital Commons Network^™

Picc-Pal: A Support Band For Independent Picc Line Use, Kylie Luker

Honors Theses

This project presents the design and evaluation of PICC-PAL, a wearable assistive device intended to improve independence and usability for patients managing peripherally inserted central catheters (PICC lines) at home. Current at-home PICC line management often requires help due to the fine motor skills needed to connect and secure tubing. This increases reliance on caregivers and introduces potential risks such as infection and dislodgement. Through stakeholder analysis, prior art evaluation, and iterative prototyping, a device was developed to stabilize the PICC line lumen and enable one-handed connection of medical tubing. Throughout the project, multiple design concepts were explored, with the …

Jtc 26: Through Her Lens, Mackenzie Ross

University of Mississippi News

This story is part of the 2026 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Blues Musician And Scholar To Deliver Annual Last Lecture, Rebecca Lauck Cleary

University of Mississippi News

OXFORD, Miss. – On his first day of teaching at the University of Mississippi in 2002, Adam Gussow showed up in Barnard Observatory right at the start of class time, sweating profusely in the August heat. His left arm was in a cast from a recent bicycle accident on Pea Ridge Road, and he was flustered and in pain.

Fifteen Years Of The Abc-Ahp-Ncnpr Botanical Adulterants Prevention Program: What Have We Learned?, Stefan Gafner, Roy Upton, Mark Blumenthal, Ikhlas Khan

Oxford ICSB

Initiated in 2011, the Botanical Adulterants Prevention Program (BAPP) was created as a partnership between the American Botanical Council, the 2American Herbal Pharmacopoeia (AHP), and the National Center for Natural Products Research (NCNPR) at the University of Mississippi to educate the herbal dietary supplement industry, regulators, and scientists in academia about adulteration of botanical ingredients. The ultimate goal of the Program was to improve the authenticity and quality of herbal dietary supplements to the consumer. Since its inception, the Program has published 100 peer-reviewed documents. Despite herbal ingredient suppliers’ and dietary supplement manufacturers’ implementation of changes in quality control specifications, …

Alkaloid Profiling Of Narcissus Poeticus L. Bulbs And Their Inhibitory Activity Of Cholinesterases, Maël Gainche, Isabelle Ripoche, Elodie Jagu

Oxford ICSB

The Amaryllidaceae family is well known for its rich diversity of alkaloids, including lycorine- and galantamine-type structures with potent cholinesterase inhibitory properties. In this study, we investigated the phytochemical composition and cholinesterase inhibitory activity of alkaloids isolated from Narcissus poeticus L., a species native to the botanically rich Auvergne region of France. Phytochemical analysis and bioguided fractionation of bulb extracts led to the identification of three known alkaloids, pseudolycorine, norgalantamine, and 2-O-(3’-hydroxybutanoyl)-lycorine, as well as a newly characterized tetrahydroquinoline derivative, poeticine A. The inhibitory activities of these compounds against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were assessed using both a standard …

Unmasking Ashwagandha Controversy: Safety, Toxicity, And Adulteration, Tahir Maqbool Mir

Oxford ICSB

Ashwagandha (Withania somnifera) is an adaptogenic shrub valued for its roots, which support systemic health. Increasing use has raised safety concerns about adulteration and hepatotoxicity. The roots of ashwagandha are primarily preferred for systemic health, while the leaves were traditionally reserved for topical applications to treat joint inflammation and promote wound healing.  Although generally considered safe, ashwagandha supplements have been linked to drug-induced liver injury, including cholestasis, jaundice, and pruritus. Reports from various organizations like LARB in the Netherlands indicate a rise in liver toxicity cases, possibly due to cytotoxic withafrin A and DNA-damaging withanone. A major concern is widespread …

Naturally Derived Kratom Extracts: Toxicological Evaluation In Humans And Rodents, Sibyl Swift

Oxford ICSB

Peer-reviewed literature provides limited toxicological data on the consumption of naturally derived kratom extracts. Given the increasing use of kratom products, understanding their safety profile is critical for public health and regulatory decision-making. To address this gap, we conducted a rodent toxicology assessment and a controlled human clinical study. Human Clinical Study: Healthy male and female participants consumed specified kratom extracts daily for 14 consecutive days under controlled conditions. Clinical observations and biochemical markers were monitored throughout the study. Rodent Toxicology Study: Equivalent extract doses were administered to rodents for 90 days to evaluate subchronic exposure. Assessments included body weight, …

Real World Fertility: From Participatory Research To Clinical Trial, Belinda Tan, Azure Grant, Ayla Barmmer

Oxford ICSB

Nutritional supplements are widely popular for female reproductive health, but their ingredients are typically studied in isolation in the laboratory. Finished products make claims based on these isolated studies, creating a gap in which impact of multi-nutrient formulas in the real world are not investigated, largely due to high research costs. Decentralized clinical research methods are modernizing clinical trials, leading to affordable, efficient evidence generation in large representative populations. Utilizing a decentralized research platform, we tested the hypothesis that specific supplement protocols would be associated with improved female health and fertility in a real world cohort. We present a novel …

Icsb Poster Session, Ikhlas Khan

Oxford ICSB

Poster abstracts from the ICSB 2026 poster session.

Metabolomic Characterizations Of Hericium Erinaceus (Bull.) Pers. And Laricifomes Officinalis (Vill.) Kotl. & Pouzar Fungal Cultures, Kyle Meyer

Oxford ICSB

We present metabolomic characterizations of Hericium erinaceus (Bull.) Pers. (lion’s mane, yamabushitake, etc.), and Laricifomes officinalis (Vill.) Kotl. & Pouzar (syn. Fomitopsis officinalis; agarikon, eburiko, etc.) fungal cultures by high resolution orbitrap mass spectrometry and HPLC-DAD. Primary focus has been applied to the cultivation of these species on brown rice, Oryza sativa L., as a solid substrate.   In the case of H. erinaceus, we have observed key differences in lipid metabolite profiles over a 28-day fermentation time series suggesting possible grain lipid feedstocks for fungal-derived lipid production, providing clear evidence of substrate biotransformation.   For L. officinalis cultures, we observe distinct …

Bioactive Metabolite Markers For Functional Mushrooms: Comprehensive Metabolomic Mapping Of Full-Spectrum Cultivated Mushrooms, Standard Production And Method Development., Julie Daoust, Ivana Blaženović

Oxford ICSB

Functional mushrooms are increasingly used in dietary supplements and functional foods, yet current scientific characterization of their chemistry remains limited by narrow extraction paradigms, limited standards availability and incomplete databases. In 2025, M2 Ingredients, in collaboration with Adikai Insights, completed a metabolomics atlas, a comprehensive untargeted metabolomics investigation of ten cultivated mushroom species grown under controlled indoor conditions in and effort to identify known bioactive molecules in whole mushroom samples to guide standard and quantitative method development targeting bioactive compounds present in the materials.   Using high-resolution mass spectrometry and advanced cheminformatics, a total of 5,139 unique functional mushroom metabolites were …

Authenticated Hericium Erinaceus Mushroom And Selected Mycelia Reference Materials For General Industry Use, Steven Dentali

Oxford ICSB

The establishment of authenticated reference materials is critical for method validation, standards development, and adulteration detection in the medicinal mushroom market. Hericium erinaceus (Lion’s Mane) is widely commercialized, yet historically has lacked species-specific analytical standards. This presentation describes the species identification protocol used by Nammex to develop and maintain authenticated H. erinaceus mushroom reference materials that support ongoing standards work, including advisory contributions to AOAC INTERNATIONAL initiatives. Production partner voucher specimens are authenticated using macroscopic, organoleptic, and morphological examination by qualified personnel, and retained as internal reference materials. Genetic verification using DNA sequencing confirms H. erinaceus identity in voucher specimens …

Determination Of Kratom Alkaloids In Botanical Products Using Multi-Criteria Lc–Ms Analysis, Mengliang Zhang

Oxford ICSB

Kratom (Mitragyna speciosa) is a botanical product widely sold in the United States as powders, capsules, tablets, gummies, and beverages. Natural kratom leaves primarily contain mitragynine (MG) as the dominant alkaloid. However, an increasing number of commercial products contain elevated levels of the more potent opioid alkaloid 7-hydroxymitragynine (7-OH) and the semi-synthetic compound mitragynine pseudoindoxyl (MGP). Reliable analytical identification of these compounds is critical for dietary supplement testing, regulatory monitoring, and public health protection. However, kratom matrices contain numerous structurally related alkaloids and isomeric compounds that complicate mass spectrometric identification and may lead to false positive assignments. The objective of …

Advancements In Extraction And Co-Extraction Of Botanicals For Standardization And Efficacy, Rory Coleman

Oxford ICSB

Historically, botanicals have served human health in traditional medicine and supplementation due to their bioactive components. Efficient, clean extractions and clinical validation have become fundamental technologies, rendering access to libraries of efficacious products. However, cost, regulatory status, and speed to market have kept many botanicals in single or simple form. Mixtures of such single botanical extracts often require large quantities for effect, influenced by chemical composition, concentration, and delivery format. During the extraction and concentration process, exogenous "bioenhancers," e.g. piperine or oil blends for hydrophilic molecules, often become a necessity, exasperating the problem.   Here, we will delve into the development …

Yeast As A "Microbial Factory", Kaila Fuller, Betsy Jean Yakes

Oxford ICSB

Yeast are eukaryotic, single-celled microorganisms that are members of Kingdom Fungi, and in the world of dietary supplements, yeast qualify as a dietary ingredient as a botanical. During fermentation, yeast naturally produce byproducts that can be harvested, purified, and sold in a dietary supplement. Advances in biotechnology have allowed for genetic modification of yeast so that yeast can produce large quantities of native or non-native constituents during fermentation, effectively making yeast a “microbial factory” for various chemicals. Chemicals produced this way can qualify as a dietary ingredient as a constituent of a botanical. Relevant examples of past submitted notifications (public …

Jtc 26: A Community Builder With A Cause, Staff Report

University of Mississippi News

This story is part of the 2026 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Windshield Not The Rearview Mirror, Dan Fabricant

Oxford ICSB

We talk a great deal about the past at ICSB and while the history is important, we still need to skate to where the puck is going. We’ll tee up where we are and where we are going when it comes to: drug preclusion; federal preemption; state regulatory efforts; hemp/cannabis; electronic commerce platforms; claims; essentiality; and much more, like what you can do to affect real change for the future of the industry.

Ole Miss Giving Day 2026 Sets Participation Record, Michael Newsom

University of Mississippi News

OXFORD, Miss. – University of Mississippi alumni, students, faculty, staff and friends stepped up again during Giving Day 2026, with a record 3,223 gifts providing $1,789,552 for programs, scholarships and student opportunities.

Growing Healthy Habits: Impacts Of A Youth Community Garden For Children In Rural Mississippi, Olivia G. Degravelle

Honors Theses

This study examines the implementation and outcomes of a Youth Garden Program conducted in Pontotoc, Mississippi. Funded by the Allstate Community Service Project Grant, the Youth Garden was constructed within the previously established Pontotoc Community Garden. The initiative comprised four weekly workshops designed for participants ranging from preschool to adolescence. Each session incorporated hands-on fruit and vegetable (FV) planting or harvesting, an educational lesson, and a complementary craft activity. Children’s FV consumption patterns, nutritional knowledge, and attitudes toward FV were assessed through pre- and post-program surveys. In addition, the photo-elicitation interview method invited participants to take digital photographs of garden …

Visual Attention And User Satisfaction In Ota Platforms: An Eye-Tracking And Big Data Approach, Aura Lydia Riswanto, Seieun Kim, Hak-Seon Kim

Faculty and Student Publications

Purpose – This study aims to investigate how visual attention to online travel agency (OTA) app elements influences user behavior and satisfaction by integrating experimental and real-world data.

Design/methodology/approach – This study used a multi-method approach combining an eye-tracking experiment with 40 participants, a post-experiment survey on usage intention and big data analysis of 5,547 Google Play reviews from five major OTA platforms, using text mining and regression techniques.

Findings – The eye-tracking results showed that users focused most on user reviews and app information, rather than logos or app names. Visual attention to reviews significantly predicted higher usage intention …

University Recognizes Top Researchers, Scholars With Annual Awards, Clara Turnage

University of Mississippi News

OXFORD, Miss. – The University of Mississippi recognized nine outstanding faculty members Tuesday (April 7) at the second annual Chancellor's Awards for Research and Creative Scholarship.

Pharmacy Matters April 2026, University Of Mississippi School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: Ole Miss Student Pharmacist Earns Top 10 Honors in National Patient Counseling Competition, Support Ole Miss Pharmacy on Giving Day, April 14, SOP Alumni Weekend: Honoring Alumni Who Lead, Mentor, and Serve, Match Day Success, Pharmacy Team Develops 3D-printed Bandage to Help Heal Chronic Wounds, Global Botanicals Conference Adds Cancer Focus, 2026 Charles W. Hartman Memorial Lecture, Dr. Aaron E. Carroll, 2026 Ronald F. Borne Endowed Lecture, Dr. Neha Pagidipati, MD, MPH, Applied Statistics Student Research Awards, CASE Workshop Selection, Image of Research Finalist, Kenvue APhA Scholarship, Alumni Insider's View Program, NACDS Rx Impact Day on Capitol Hill, …

Ole Miss Launches Americorps Program Mentoring Youth Statewide, Marvis Herring

University of Mississippi News

OXFORD, Miss. – University of Mississippi junior Lauren McKay changed her major three times before she found herself sitting across from a group of Oxford High School students, talking about geometry, strained relationships and how to push through the things you'd rather not do.

One Sister’S Fight Inspires Statewide Push For Bone Marrow Donors, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – University of Mississippi freshman Ali Hargett has learned about bravery and organization during her first year in college, but not in a class. Instead, she has been watching her 11-year-old sister, Cate, who is in bone marrow failure.

Issue 481 March 5-March 19, 2026, The Local Voice

The Local Voice

Featured Articles: "Whispers in the Pews:. How Small Talk Shapes Evangelical Identity and Christian Nationalism."; "Izzy Arthurs’ Talisman of Grief."; "Historian Starke Miller Announces 2026 Spring Tour Schedule for Oxford and Ole Miss in the Civil War."; "The View Beyond The Balcony: What Could We Do with $8M?."

March 5, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

February 12, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Curriculum Materials Cataloged For Browsing, Michelle Emanuel

Library Publications

When the University of Mississippi Libraries acquired a collection of state-adopted school textbooks for K-12 from its School of Education, a decision was made to catalog the collection for browsing to anticipate the needs of its primary users, both “in service” and “pre-service” teachers. The textbooks would be grouped according to their grade level, and cuttered by subject area, instead of being classed according to its subject area. As the collection would be integrated into the regular circulating collection, and not into a curriculum materials center, issues arose for both technical services and access services throughout the process, from cataloging …

Black Swans And Safety Nets: Food Aid, Dispersal, And Eugenics In Corbin Hollow, Glenn Davis Stone, Richard K. Robinson

Southern Anthropologist

No abstract provided.

January 20, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.