Digital Commons Network^™

The Role Of Age Ligand And Rap1a In Myofibroblast Signaling Cascade In Type 2 Diabetes Mellitus-Induced Cardiomyopathic Conditions, Camilla Puglia

Honors Theses

Diabetes is one of the leading causes of death in the United States, taking more than 90,000 lives annually. Type 2 diabetes mellitus-induced cardiac fibrosis is a common condition seen in diabetic patients. The AGE/RAGE signaling cascade has been strongly associated with this supposed cardiac fibrosis along with hyperactive myofibroblasts which excessively remodel extracellular matrix tissue, leading to damaged and enlarged heart muscle tissue. In diabetic patients, Advanced Glycation End Products (AGEs) are produced in abundance and accumulate in the extracellular matrix of heart tissue. To investigate the role of of the AGE ligand on fibroblast behavior, increasing amounts of …

It's Just Caring: Improving The Museum Experience For Visitors With Autism Through Social Narratives, Reagan R. Stone

Honors Theses

This project explores how museums can improve the visitor experience for visitors with disabilities, more specifically for visitors with autism. In general, museums are environments that have a specific set of rules, guidelines, and built-in social interactions that visitors are expected to understand and follow. These guidelines, as well as the sensory overload that exists within a new environment, can make visiting the museum a stressful, and even negative experience for individuals with autism and their families. A social narrative, a simple written and visual guide that explains characteristics of new environments and various aspects of social situations, is a …

Investigation Into The Detection Of Drug Metabolites In Latent Fingerprints, Paige Oden

Honors Theses

Fingerprinting has proved a useful mode of identification for thousands of years. Following numerous technological advancements, it has become a technique for categorizing and keeping track of people over large geographical spaces for almost half of a century. Those living in the beginnings of fingerprinting used them as a form of signature as it was something completely unique to each individual that could not be replicated. Although they are no longer used as the primary form of signature, it certainly remains a biomarker of identity. Over the past century the practice has been heavily refined in order to identify people …

Alternative Sweeteners For Cultivating Water Kefir Grains, Morgan Barnes

Honors Theses

Water kefir is traditionally fermented using dark brown sugar due to a fast growth rate, however the use of other sweeteners, such as honey, is relatively unexplored. This paper describes the investigation of using alternative mediums made with honey, agave nectar, Truvia/stevia, and monk fruit sweetener, each supplemented with dark brown sugar on the biomass growth of water kefir grains (WKGs). Growth in these alternative mediums was compared to WKG growth in the standard medium prepared using only dark brown sugar. Two trials were conducted, each with three replicates for each experimental medium as well as three replicates of dark …

Investigation Into The Comorbidities Of Disordered Eating And Social Anxiety Disorder In College Students, Alice Mccraney

Honors Theses

In recent years, psychiatrists have reported a trend that individuals with social anxiety disorders are more likely to also have disordered eating and vice versa. Research into this connection has suggested that risk factors, such as stress reactivity, negative self- esteem, perfectionism and fear of negative evaluation are potential links. This is important because understanding the correlation between the two disorders could help develop better treatments plans for people who suffer from these disorders. This study investigates the relationship between the two. A total of 257 college students between ages 18-22 completed a questionnaire using the Disordered Eating Attitude Scale …

Issue 393: May 5-19, 2022, The Local Voice

The Local Voice

No abstract provided.

The Effect Of Age Concentration And Glucose Levels In Rage-Mediated Cardiac Fibroblast Migration In Type 2 Diabetes, Lorral Kanauss

Honors Theses

Diabetes is one of the largest health concerns in the United States. Its continuous increase in prevalence has led to it being one of the largest healthcare costs and consistently listed as one of the leading causes of death. That being said, diabetes also increases the risk of other health conditions, one of which is cardiovascular disease. Left ventricle hypertrophy resulting in the stiffening of the left ventricle and diastolic dysfunction is one form of cardiovascular disease associated with diabetes. Thought to be impacted by decreased fibroblast migration in the extracellular matrix, the experiments performed in this study seek to …

Kritika Gupta Named Graduate School Class Marshal, Staff Report

University of Mississippi News

Doctoral candidate praised for her work in child nutrition and school wellness

Mississippi Pharmacists’ Perceptions Of Dietary Supplements, Emory Booth

Honors Theses

Dietary supplements are often a controversial topic among healthcare professionals. Many view supplements positively and appreciate the health benefits they can provide. Others are wary of the decreased regulation dietary supplements are subject to and believe that the benefits of supplements do not outweigh the risks. Dietary supplements are of particular interest to pharmacists, as they are often sold at their place of work, and pharmacists have to consolidate their patients’ supplement use with their medication use. The purpose of this thesis is to evaluate the viewpoints of Mississippi pharmacists in relation to dietary supplements. A survey was sent to …

Exogenous Supply Chain Shocks And Onshoring: An Analysis Of Thetrump Trade War And The U.S.-China Bilateral Trade Relationship, Benjamin Sullivan

Honors Theses

This paper examines the effects of the supply chain crisis on the U.S.-China bilateral trade relationship and on the health of the U.S. manufacturing sector. The policy goals and decision making of both the Trump administration and the Chinese Communist Party are examined, it is determined, within the context of the U.S.-China Trade War, that the Chinese Communist Party made more effective long-term policy decisions than the Trump Administration. However, despite the U.S’s policy failures, this paper finds that U.S. manufacturing competitiveness, relative to China, has actually increased in recent years. This relative increase in manufacturing competitiveness is driving the …

Grit And Food Security Among Female Caregivers In A Rural, Appalachian Mississippi County, Mary Frances Buzhardt

Honors Theses

Background: Grit is the determination and resolve required for accomplishing long term goals.

Research Outcome: This study examined: 1) differences in grit by household food security status; and 2) relationship between grit and household food security status among female caregivers of elementary school children in a rural, Appalachian Mississippi county after participation in a produce voucher intervention.

Methods: Female caregivers (n=1,144) were recruited at three elementary schools in MS in November 2017 and enrolled into a produce voucher intervention ($11/week over 10 weeks). Validated measures of household food security status (10-item USDA survey) and grit score (8-item Duckworth survey) were …

The Dream Of The Common Good: Not A Nightmare, Jackson Gregory Dellinger

Honors Theses

This paper examines an emerging position in the philosophy of law, common-good constitutionalism. In the first two parts of the paper, I explain the position and constitutionalism more generally, examining how common-good constitutionalism fits within the definition of constitutionalism providing by a neutral scholar. In the next five parts, I attempt to show that common-good constitutionalism’s preference for explicit adherence to the common good does not violate constitutionalism. In doing so, I provide an examination of common-good constitutionalism’s relationship with three important constitutional principles and the separability of common-good constitutionalism as a whole and the infamous views of its most …

Sources Of Patient Information For Type 2 Diabetes Self-Care In Northern Mississippi, Minh-Sang La

Honors Theses

Given the prevalence of Type 2 Diabetes Mellitus in the United States and the continuous rise of cases, especially within Mississippi, there is an increasing need to identify if, and how, patients with Type 2 Diabetes receive information about self-care. While there is data available on the topic of where patients receive their information and the influence it has on their health in other countries of the world, the research on the source of Type 2 Diabetes education in the United States is scarce. Therefore, this study aims to bridge the gap of understanding where patients with Type 2 Diabetes …

Content Analysis Of Vitiligo Portrayal On Social Media, Mary Miller

Honors Theses

Given that vitiligo affects a small percentage of the world population, and its affects are not widely known, there is an increasing need to learn of its effects on those with vitiligo, both physical and psychological. Social media has become an influential platform to spread awareness and build confidence in those with vitiligo. This study aims to find how vitiligo is portrayed through social media using content analysis procedures. This is a cross-sectional content analysis that utilized a codebook to analyze Instagram posts. The results were analyzed by interrater reliability and frequency for each coder. The findings of this content …

How Immigration Policy Affects Migratory Flows And Immigrant Experiences: A Comparative Analysis Of Policy Impacts On Northern Triangle And Venezuelan Immigrants In The United States, Audrey Lynn Mcdonough

Honors Theses

In the past two decades, the US has experienced a large influx of immigrants from Venezuela and the Northern Triangle countries of Guatemala, Honduras and El Salvador. Due to these unprecedented increases, there has been numerous notable shifts in Immigration control policy between the presidencies of Barack Obama and Donald Trump. Generally, policies under Obama were favorable and reflected pro-immigrant rhetoric. Meanwhile, Trump took a drastic turn toward restrictionist, unfavorable policies. This study aims to examine the impact of immigration policy on migratory flows and the immigrant experience in the US. Using both quantitative and qualitative methods, I examine data …

Firsthand Experience In A Community Pharmacy Through The Lens Of A Pharmacy Technician, Khamariah Patrice Yelder-Anderson

Honors Theses

In the first chapter, I discussed three of the major issues in a community pharmacy which are rude customers, phones, and shorter hours. Technicians have to deal with very opinionated customers who can come off as insolent. The phones are a popular mode of communication for both the patients and physicians but that doesn’t account for the added demands it places on pharmacy workers. Lastly, the pharmacy has experienced later openings with earlier closings that have left filled queues and unhappy customers. The next chapter, interpersonal dynamic, takes a deeper look into how various roles of the pharmacy engage with …

A Survey Of The Presentation Of Pharmacogenomic Testing For Psychotropic Medications In Rural Areas, Laken Hancock

Honors Theses

The purpose of this research is to assess the knowledge and opinions of the general public in rural areas in regard to genetic testing and pharmacogenomics. 40 people from self-identified rural areas participated in this study by completing an online Qualtrics questionnaire and an in-person or online semi-structured qualitative interview. The Qualtrics questionnaire measured demographic information, as well as depression, anxiety, stress, positive affect, and negative affect using the Depression, Anxiety, and Stress Scale-21 (DASS-21) and the Positive and Negative Affect Scale (PANAS) measures. The semi-structured qualitative interview included questions pertaining to the decision support tool (DST) presented to participants, …

Twins Find Ole Miss Family Together - Journey To Commencement, Sydney Dupriest

Journey to Commencement

A twin bond supported Michael and Lauren Taplin as they found their way at the university.

A Utilization Focused Evaluation Of 2nd Chance Mississippi, Kathryn Mccullouch

Honors Theses

This study is a Utilization Focused Evaluation of 2nd Chance Mississippi, a local non-for-profit organization in Oxford Mississippi. The purpose of a Utilization Focused Evaluation is to provide key stakeholders with practical findings and recommendations that will be useful for future operations. The key stakeholders were identified as the administrators of 2^nd Chance, Zach and Dickie Scruggs, Catti Beals, and Sarah Rose Lomenick. Research questions were developed with the stakeholders and were as follows:

1) What are the objectives of 2^nd Chance Mississippi?

2) Are 2^nd Chance Mississippi objectives being met? If so, how?

3) What are …

The Role Of Mitochondrial Dysfunction In Causing Hypertension During Pregnancy As Observed In The Rupp Model Of Preeclampsia, Michael Franks

Honors Theses

Preeclampsia (PE) is a disease characterized by new-onset hypertension in the third trimester of pregnancy, endothelial dysfunction, and placental ischemia. Contributory to these characteristics are circulating factors such as agonistic autoantibodies to the angiotensin I type II receptor (AT1-AA), CD4+ T cells, natural killer cells (NK), and oxidative stress, which I will show to contribute to renal and placental mitochondrial dysfunction during pregnancy. The adoptive transfer of CD4+ T cells from the Reduced Uterine Perfusion Pressure (RUPP) rat model of PE to a healthy normal pregnant rat has been shown to result in many of these characteristics, including AT1-AA production. …

The Interaction Between Anxiety Sensitivity And Sleep Disturbance In Relation To Alcohol Use Among Adolescents, Gabrielle Meshell Armstrong

Honors Theses

Both substance use and sleep disturbance are common in adolescence. Additionally, alcohol use specifically is positively associated with a number of sleep disturbances. However, little to no research has examined factors that may influence the relation between problematic alcohol use and sleep disturbances among adolescents or adults. One factor that may be particularly important to consider in this regard is anxiety sensitivity (AS; i.e., the tendency to interpret unpleasant physiological sensations as dangerous). Among previous studies, anxiety sensitivity has been found associated with both increased alcohol consumption and sleep disturbances. The current study evaluated the main and interactive effects of …

Increasing The Student Activity Fee, Alexandria Bea Mabry

Honors Theses

The Student Activity Fee is a five-dollar fee paid by every graduate and undergraduate student at the University of Mississippi through their university tuition. The purpose of the Student Activity Fee is to support any efforts and passions of student organizations to allow them the financial freedom to host intentional programming for students or provide items needed for the function and success of that organization. The Student Activity Fee Fund was estimated to be depleted by Fall 2023. Therefore, in order to protect the Fund, a Student Activity Fee increase to two-dollars per credit hour was proposed to the student …

Pre-Practice Hydration Status Of Collegiate Male American Football Players With Sickle Cell Trait, Sara Hoffman

Honors Theses

Since 2000, 63% of deaths associated with college football were due to complications, such as sickling events; however, sickle cell trait (SCT) only affects 3-4% of participating athletes. Sickling events can be exasperated by conditions, including heat exposure, dehydration, and intense physical activity and lead to rhabdomyolysis and death. Assessing hydration status is crucial for athletes and the use of urine specific gravity (USG) has been shown to provide rapid and valid results. The purpose of this study was to assess the prevalence of dehydration among SCT carrying American college football players.

Division I collegiate football athletes participated as part …

Early Developmental Exposure To Δ9-Tetrahydrocannabinol Causes Hyperactivity In Larval Zebrafish That Persists Into Adulthood, Victoria Jackson

Honors Theses

Due to the increasing availability of Δ9-tetrahydrocannabinol (THC), evaluation of the potential adverse behavioral effects following exposure to this cannabinoid during early development is crucial. Following exposure to 0.08, 0.4, or 1 µM THC as larvae (6-96 hours post fertilization), this study measured the latent behavioral effects caused by THC through testing the fish at the following life stages: larval photomotor response (LPR) at 120 hpf, and open field testing (OFT) at 3 weeks post fertilization (juvenile), 11 wpf (onset of sexual maturity) and 24 wpf (adulthood). During the LPR test, hyperactivity in the dark phase was evident in larval …

Applying Deliberate Practice To Learning Psychotherapy Techniques, Nikyra Jenkins

Honors Theses

Deliberate practice has commonly been used in areas such as music, chess, and medicine, but there is a lack of deliberate practice found in psychotherapy. The purpose of this study was to examine whether deliberate practice can be applied to learning psychotherapy techniques in a novice learner (the author of this study). The study also aimed to research the anxiety and reactivity levels of the subject in response to performance during and after the session. The author independently learned modules from the Unified Protocol manual and then engaged in role-play sessions with an expert. Before beginning each exercise, the subject …

Case Studies In Accountancy, Michael Keene

Honors Theses

Case Studies in Accountancy is a compilation of case studies completed in fulfillment of ACCY 420. My cases are titled as followed: A Tale of Two Cities, Financial Statements, Presidential Debate, Tax Cuts and Job Act and Taxodus, Professional Interview, Financial Crisis, Case Competition Amazon Overview, Case Competition Amazon Audit Analyst, Case Competition Amazon Tax Advisor, Case Competition Amazon Advisory Consultant and Case Competition Amazon’s Equity Position. These cases covered a variety of topics in the world of accountancy as well as touching on our personal lives. In the first semester of the course, cases were typically individual before moving …

How Integrated Marketing Communications Can Be Used To Better Engage Generation Z In Bridge Building, Gracie Bynum

Honors Theses

The use of Integrated Marketing Communications holds strong promise for engaging Generation Z in the work of bridge building. The work of bridging is dedicated to healing America by decreasing political polarization and bridging divides between people who think differently. The bridging space has grown drastically in the last few years because of a variety of factors including, but not limited to: increasing polarized political elections, rising racial tensions, and the COVID-19 pandemic. It is important that Generation Z, the most educated and diverse generation, is engaged in this space in order to create a less divided America. I conducted …

Financial Accounting Case Studies, Mark Miller

Honors Theses

The purpose of this thesis is to study and reflect on a variety of different aspects of the accounting profession and the professional world at large. Over the course of two semesters, we engaged independently and collectively with our peers in some of the deepest dives into our future profession of our academic careers. Each of the initial cases broadened my horizons and brought to light much of accounting that I had yet to be exposed to. Ultimately in the second semester we were divided into groups to work on series of cases revolving around one major business entity. In …

Contributions Community Health Centers In The Delta Have Made During The Pandemic And Their Future, Ajah Tiyanna Singleton

Honors Theses

Community health centers that are located in the Mississippi Delta serve as critical points of contact for residents pertaining to medical care. The framework for the services provided locally, and nationally, originate from the now Delta Health Center in Mound Bayou, MS. The care that providers within these institutions have transformed over the course of the pandemic, and the aid rendered to patients have enabled residents to maintain their current level of health. Analyzing the various services provided during this time will allow for stakeholders to determine the next steps for these institutions as the imminent transition into a COVID-19 …

A Trained Eye: Optometrists' View Into Primary Care, Louis C. Magee Iii

Honors Theses

The aim of this thesis is to explore and present the auxiliary responsibilities of doctors of optometry, particularly those involved with primary health care such as screening for serious diseases. This idea was approached by researching the technological capabilities of optometrists, the diseases and conditions they commonly detect, as well as the barriers preventing some people from receiving proper eye care. The importance of optometrists as primary care providers is steadily rising alongside their capabilities. There are many instances within a routine eye exam in which an optometrist is able to detect and recommend treatment of a serious disease. Also …