Digital Commons Network^™

Jtc 24: First-Gen Student Is Going Places, Edwin Smith

University of Mississippi News

This story is part of the 2024 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Adversity To Action: A Case Study Analysis Of Crisis Leadership, Isabelle Weatherington

Honors Theses

This thesis examines leadership through crisis contexts. I aim to answer two research questions. (1) How do crisis management frameworks intersect with the leadership strategies and characteristics of the person in charge? And (2) How must a leader adapt their natural leadership style and characteristics according to the nature and level of the crisis at hand to ensure leadership effectiveness? To answer these, a comparative case study analysis was performed on the following cases: Winston Churchill and World War II (Case one), George W. Bush and the September 11th, 2001 terrorist attacks (Case two), and Thad Allen and Hurricane Katrina …

Spatial Ability Tests And Course Performance In Human Anatomy And Physiology I Students, Madeline Hinton

Honors Theses

Madeline Hinton: Spatial Ability Tests and Course Performance in Human Anatomy and Physiology I Students

(Under the direction of Dr. Carol Britson)

Visuospatial perception processing is our ability to make inferences about what an object might look like from different angles just by looking at one angle of the object or by looking at a two-dimensional representation of it. This is a skill tested on the perceptual ability portion of the Dental Admissions Test (DAT), and it is also crucial for Human Anatomy and Physiology (HAP) students to be proficient in this skill in order to successfully navigate the organ …

04.29.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Locating ORSP training in Blackboard, Marta Panickar, MS Aerospace and Defense Symposium, NSF Common Forms in SciENcv

Pitching It Forward, Bill Dabney

University of Mississippi News

OXFORD, Miss. – Former pro baseball player Jamey Price was in peak physical condition while pitching for the Ole Miss Rebels – a testament he credits to the health, strength and wellness coaching he received at the University of Mississippi.

Jtc 24: Making His Mark, Edwin Smith

University of Mississippi News

This story is part of the 2024 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Jtc 24: Michigan Dentistry By Way Of Ole Miss, Kayla Vonburg King

University of Mississippi News

This story is part of the 2024 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Jtc 24: For The Love Of Family, Natalie Ehrhardt

University of Mississippi News

This story is part of the 2024 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Game Night! Assessment Of Playability And Learning Effectiveness Of Active Learning Games In Human Anatomy And Physiology Students, Hannah Brady

Honors Theses

Human Anatomy and Physiology (HAP) courses are a requirement for many students pursuing an education in healthcare. Students tend to dread these courses for their abundance of information in such a short amount of time. These courses tend to have a low success rate because students are not adequately prepared for this upper-level class that requires intense dedication and studying. This problem for students is extreme as these courses are required for most pre-health undergraduate students, and these courses may predict their success in their future education. HAP professors are constantly trying to figure out better ways to get students …

College Of Liberal Arts Annual Awards Ceremony, 2024, Lee Cohen, University Of Mississippi. College Of Liberal Arts

Liberal Arts Awards

The College of Liberal Arts presented awards to its faculty, staff, students, and alumni in the Gertrude C. Ford Center Student Union Ballroom.

Record Boren Cohort Seeks New Opportunities To Learn Languages, Erin Garrett

University of Mississippi News

OXFORD, Miss. – Ten University of Mississippi students have been awarded David L. Boren scholarships from the National Security Education Program, the most ever in a single year at Ole Miss.

Reproductive Justice In Mississippi: A Call For Reform And Acknowledgement, Andie Udziela

Honors Theses

In this thesis, I apply the values of the Reproductive Justice Movement to reproductive healthcare resources in Mississippi to advocate for reproductive policy reform. I begin by navigating the historic racial discrimination in gynecology and how it manifested in Mississippi. Dr Sim’s abusive experimentation on Anarcha, Betsy, and Lucy depict how Anti-Black racism took root in gynecology and obstetrics and was later expanded on by the eugenic goals of white supremacy and the feminist movement through Margaret Sanger and the Mississippi Appendectomy. Then I discuss the current availability of reproductive care in Mississippi to low-income individuals to emphasize socioeconomic and …

April 25, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

High Level Of Fat-Transporting Molecule Linked To Alzheimer's, Clara Turnage

University of Mississippi News

OXFORD, Miss. – A new study by researchers at the University of Mississippi and Harvard University may have uncovered a risk factor for Alzheimer's disease.

Jtc 24: Passion, Persistence Produce Phenomenal Payoff, Edwin B. Smith

University of Mississippi News

This story is part of the 2024 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

How Witnessing Domestic Violence Affects The Future Of Children: An Exploratory Study, Victoria Cleckler

Honors Theses

Domestic violence (DV), also known as Intimate Partner Violence (IPV), is a widespread issue that affects many people, families, and communities, with one in four women and one in nine men falling victim to domestic violence each year in the United States. However, these statistics only consider what has actually been reported. More than 44% of domestic violence cases go unreported each year. It can be inferred that a drastic number of children are also affected. Children who witness domestic violence are indirect victims of DV, as they experience psychological and emotional turmoil simply by witnessing the abuse. However, there …

Library Faculty To Help Researchers Access Massive Biomedical Database, Benita Whitehorn

University of Mississippi News

OXFORD, Miss. – The University of Mississippi Libraries can help researchers with unprecedented access to a massive trove of medical data, thanks to an award from the National Institutes of Health.

Grove Scholars Profile: Jatoni Donelson, Jatoni Donelson, Eva Luter

Grove Scholars

No abstract provided.

Perseverative Thinking And Thought Suppression: Links To Medication Non-Adherence Among Adults With Type 2 Diabetes, Aswin Arunachalam, Aaron Lee

Honors Theses

Medication nonadherence in patients with type 2 diabetes contributes to poor glycemic control which often results in the development of serious and irreversible diabetes-related complications. This study examines the role of the maladaptive cognitive processes of rumination and thought suppression on medication nonadherence in patients with type 2 diabetes. The sample for this study (N = 343) consisted of adults (mean: 55, range: 19 – 85) with type 2 diabetes enlisted through a web-based platform. Participants completed a series of validated questionnaires including the Perseverative Thinking Questionnaire, White Bear Suppression Inventory, and Difficulties in Emotion Regulation Scale. Binary logistic regression …

Grove Scholars Profile: Trynica Wash, Trynica Wash, Jaylin R. Smith

Grove Scholars

No abstract provided.

Beyond Appearance: Nmr Metabolomics For Mushroom Quality Assurance And Authenticity, Arun Krishna Murthy, Amber Thelen

Oxford ICSB

Driven by their prominent health benefits, mushrooms are extremely popular in food and nutraceutical sectors, incidentally attracting food fraud such as species mislabeling and substitution, adulteration, and contamination with synthetic and cheaper substitutes, severely affecting the supply chain and raising concerns among consumers about product safety and quality. Untargeted chemical profiling using Nuclear Magnetic Resonance (U-NMR) spectroscopy, in conjunction with Multivariate Statistical Analysis (MSA) proves to be a superior and universally recognized analytical method in simultaneously addressing these concerns and inadequacies of conventional analytical methods. A comprehensive and robust 1H NMR spectral library is built using validated mushroom samples of …

Metabolite Profiling Of Functional Fungi Strains Of Hericium Erinaceus & Cordyceps Militaris: Using Phenotypes, Untargeted Metabolomics By Mass Spectrometry And Cell-Based Assays, Julie Daoust

Oxford ICSB

Mushrooms have a long tradition of use as medicinal and functional ingredients however the lack of development in testing methods currently limits our ability to characterize these products. Selecting the right strain or processing method is currently challenging given the lack of commercially available analytical methods to detect or quantify secondary metabolites with therapeutic endpoints. Very little is known about the variability of these metabolites between strains of the same species and between identical strains grown in different conditions therefore an untargeted analytical method was needed to adequately assess impact of strain genetics and growing methods for M2 Ingredients cultures …

Re-Discovery Of Fungi, Christopher Hobbs

Oxford ICSB

This will be a very concise overview of the laboratory and clinical work that has been published on the health and medical benefits of medicinal mushrooms and mycelium. Medicinal mushroom and mycelium-based products currently on the market will be critically reviewed, specifically focusing on identifying the 5 most important constituent groups intensive world-wide research has identified as providing the intended benefits of these products, and what leading companies as well as startups are doing to insure their products contain them in meaningful amounts.

Evaluation Of Botanical Extracts For Cytochrome P450 Inhibition Mediated Drug Interactions, Angela I. Calderón, Zarna Raichura, Kabre Heck, Jaewoo Choi, Mikah Brandes, Cody Neff, Claudia Maier, Amala Soumyanath, Robert Arnold

Oxford ICSB

There has been remarkable growth in consumption of botanical dietary supplements (BDS), making it important to understand the safety profile of BDS with respect to the pharmacokinetic properties for any potential of botanical-drug interactions. One such botanical interactions which has gained significant attention involves inhibition of cytochrome P450 (CYP450) enzymes by co-administered drugs. Our study involved examining two widely used botanicals, ashwagandha and açaí for any potential inhibition of CYP450. Four different ashwagandha extracts were tested, resulting in inhibition of CYP2B6 with IC50 < 100 µg/ml of extract and showed potential of time-dependent inhibition for CYP2C9 and CYP2D6 with an IC50 ~ 200 µg/ml of extract. In the case of açaí, seven different extracts were tested and only CYP2C9 was inhibited. The acidic methanol extract of açaí formulation showed an IC50 of 0.3 µg/ml of extract indicating potent inhibition of CYP2C9, while the methanol (IC50 ~ 91.75 µg/ml) & ethanol extracts of Mountain Rose açaí powder showed weak inhibitory effect with an IC50 < 100 µg/ml of extract for CYP2C9. The results reflect that both botanical extracts showed potential of CYP450 inhibition, suggesting that compounds in BDS can prolong the half-lives of medications leading to extended action or toxicity. Next step involves, testing subfractions of these extracts to identify the compounds responsible for the observed inhibition.

Multifaced Factors To Cause Conflicting Outcomes In Drug-Herb Interactions Mainly Focusing On Reverse Pharmacokinetics, Young Hee Choi

Oxford ICSB

Metabolic enzyme and/or transporter-mediated pharmacokinetic (PK) changes in a drug caused by concomitant herbal products have been a primary issue of herb and drug interactions (HDIs), because PK changes of a drug may result in the alternation of efficacy and toxicity. Studies on HDIs have been carried out by predictive in vitro and in vivo preclinical studies, and clinical trials. Nevertheless, the discrepancies between predictive data and the clinical significance on HDIs still exist, and different reports of HDIs add to rather than clarify the confusion regarding the use of herbal products and drug combinations. Here, the underlying mechanisms causing …

Screening Of Medicinal Herbs To Predict The Potential Perpetrators Of Herb-Drug Interaction, Ikhlas A. Khan, Amar G. Chittiboyina, Shabana Khan, Bill Gurley, Islam Husain

Oxford ICSB

Over time, the popularity and consumption of herbal medicine and its products like nutraceuticals, botanical drugs, and dietary supplements have increased immensely. Parallelly, several health issues associated with the overconsumption of these products have also been raised, which has attracted enormous attention. Herb-drug interaction (HDI) is a health issue caused by herbs or phytochemicals that modulate the homeostasis of drug-metabolizing enzymes (CYPs) and transporters, thus altering the pharmacokinetic of clinical drugs. To date, only a few medicinal herbs, such as Hypericum perforatum, Hydrastis canadensis, Glycyrrhiza glabra, and Camellia sinensis etc., were recognized as HDI perpetrators. However, many need to be …

New Natural Product Certified Reference Material Resources Supported By The Nih Office Of Dietary Supplements, Adam Kuszak, Zoe Ruan, Linda Smith, Sarah Ajaz, Uma Srennivasan, Sabrina Giddings, Daniel Beach, Pearse Mccarron, Stephen Wise

Oxford ICSB

The NIH Office of Dietary Supplements (ODS) Analytical Methods and Reference Materials (AMRM) Program supports the development of tools that promote and facilitate rigorous and reliable characterization of dietary supplement (DS) identity, composition, and purity, as well as assessments of authenticity and contamination of botanical and other natural product raw materials and finished products. AMRM goals are accomplished through development and validation of quantitative and qualitative methods, production of certified reference materials (CRMs), and support of dietary supplement focused laboratory quality assurance programs. Recent advances in DS analytical resources supported by AMRM include an expanded availability of CRM calibration solutions …

The Botanical Safety Consortium: Collaborative Effort To Improve Botanical Safety Testing Methods, Connie Mitchell, Cynthia Rider, Julie Kzykwa

Oxford ICSB

The use of botanical dietary supplements is increasing, making their safety a crucial issue for public health. This article discusses the role and goals of the Botanical Safety Consortium (BSC), a collaborative effort between the US FDA, the National Institute of Environmental Health Sciences, and the Health and Environmental Sciences Institute. Formed through a Memorandum of Understanding, the BSC aims to improve safety evaluation methods for botanicals. It operates as an international platform where experts from various sectors, including government, academia, industry, and non-profits, collaborate to advance and apply new approach methodologies (NAMs) for the safety assessment of botanical products. …

Issue 441: April 18-May 2, 2024, The Local Voice

The Local Voice

No abstract provided.

University Celebrates Community, Employee Service, Edwin Smith

University of Mississippi News

OXFORD, Miss. – The University of Mississippi recognized accomplishments in community-engaged research, learning, service and scholarship by its students, faculty and staff members on Tuesday (April 16) during the annual Celebration of Service Awards.