Digital Commons Network^™

Fda Investigational New Drug (Ind) Applications, Cassandra Taylor

Oxford ICSB

Current Federal law requires that a drug be the subject of an approved marketing application before it is transported or distributed across state lines. Because a sponsor will probably want to ship the investigational drug to clinical investigators in many states, it must seek an exemption from that legal requirement. The IND is the means through which the sponsor technically obtains this exemption from the FDA. During a new drug's early preclinical development, the sponsor's primary goal is to determine if the product is reasonably safe for initial use in humans, and if the compound exhibits pharmacological activity that justifies …

Natural Products In Food And Agriculture, Stephen O. Duke

Oxford ICSB

Before the National Center for Natural Products Research (NCNPR) existed, I was Director of a USDA weed management lab. Two of my interests were natural products as herbicides and the chemical ecology of weed/crop interactions (allelopathy). Dr. James McChesney and I had several conversations about his vision for the NCNPR on the University of Mississippi campus. I was very interested in becoming a part of this, as his plan was to have a USDA lab that would study natural products for use in food and agriculture as part of the center. The USDA Agricultural Research Service established the Natural Product …

The True History Of Aloes And Beyond, Ben-Erik Van Wyk

Oxford ICSB

The recorded history of aloes dates back thousands of years, with early recordings in the Papyrus Ebers (ca. 1550 B.C.) and in Dioscorides’s Herbal (1st cent. A.D.). Aloe has been used as a two-in-one medicine, not only by early explorers but also as a material of strategic military importance, with the yellow juice effective against the stomach problems of an army on the march and the white juice (gel) used to treat the wounds of battle. Aloe vera is the correct name for the “true aloe”, as the specific epithet “vera” indicates. The origins of the plant are shrouded in …

Evaluation Of Seizure Recognition And First Aid Training Course And Improving Self-Efficacy Related To Medical Emergencies In Mississippi, Anna Katherine Herrington, Collin Earl Wayne Crawson, Daniel Robert Zuckerman

Honors Theses

Within recent years, there has been increased attention to the growing physician shortage across the United States. This shortage has placed substantial strain upon regions of lower healthcare access, particularly those of rural regions such as much of the state of Mississippi. As rural healthcare providers are placed under more strenuous conditions, they encounter issues of increased patient volume, lack of a trauma team, or adequate transportation to higher-level care facilities. These issues may exacerbate the present inequities in cost of living, access to adequate healthcare, and the distress caused by these concerns. Individuals with epilepsy are one cohort with …

April 11, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

04.08.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Nature Masterclasses Overview, Mary Lea McMillan, Cost Transfer Policy, NSF Author and Allocation citing

Novel Tests For Motor And Spatial Deficits In Zebra Finches Verify A Role For Aromatase And Estradiol In Improving Spatial But Not Motor Outcomes Post-Cerebellar Lesion, Simran Patel, Lainy B. Day, Mathew Thibodeaux, Demetria Tolbert, Chyna-Rae Dearman, Gerald W. Stinson, Joshua Hamer, John C. Garner, Dwight Waddell

Neuroscience Research Showcase

Objective: Test the role of Arom and E2 in recovery of zebra finch posture and spatial learning post-CB lesion.

Simran Patel^1,2, Lainy B. Day¹, Mathew Thibodeaux¹, Demetria Tolbert^1,2, Chyna-Rae Dearman¹, Gerald W. Stinson¹, Joshua Hamer¹, John C. Garner³, Dwight Waddell ⁴ (¹ Department of Biology, University of Mississippi, University MS; ² Mississippi INBRE Research Scholar, University of Southern Mississippi, Hattiesburg MS; ³ Department of Kinesiology and Health Promotion, Troy University, Troy, AL 36082; ⁴ Department of Biomedical Engineering, University of Mississippi, University, MS …

Influences Of Dietary Enrichment In Juvenile And Adult Male Zebra Finch (Taeniopygia Castanotis) On Cheek Patch Growth And Color, Carley Craig, Mathew Thibodeaux, Mary Tharp, Gabrielle Morris, Woodward Young, Belinda Bagwandeen, Lainy B. Day

Neuroscience Research Showcase

Zebra finches (ZF) are sexually dimorphic. In captive ZFs, enriched diets increase cheek area and alter color, increasing adult male attractiveness. In the wild, breeding and brooding occur when proteinaceous seeds available. Our experiment tests whether supplemental egg food benefits captive non-breeding adults and juveniles.Pre-experiment, adults fed eggs, cuttlebone & bread 2x week. Other facets of our experiment showed enriched diet led to decreased reactive CORT levels and increased body mass, with the largest increase in females.

All authors are affiliated with the University of Mississippi Department of Biology and Neuroscience Minor.

Nhm 728: Advanced Survey Data Analysis, Yunhee Chang

GMAS Course Syllabi

No abstract provided.

Pol 551: Empirical Political Analysis, Julie Wronski

GMAS Course Syllabi

No abstract provided.

Policy Brief: Decreasing Unintended Pregnancy Rates In Mississippi, Jaycee S. Pilcher

Honors Theses

On June 24th, 2022, the U.S. Supreme Court’s decision to reverse Roe v. Wade marked a pivotal moment, eliminating the federal right to pregnancy termination. This thesis examines the challenges of restricted abortion access and emphasizes preventative strategies for unintended pregnancies. Analyzing both pre- and post-pregnancy interventions, such as enhanced sex education, hormonal contraceptives, insurance coverage, prescribers, and post-pregnancy policies, this thesis urges Mississippi residents and legislators to consider policy adjustments for reducing the occurrence of unintended pregnancies.

This research includes an analysis of literature, legislative records, and statistical data. It takes a comparative approach to evaluate the effectiveness of …

February 29, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

A 'Game Changer' For Incarcerated Students, Jonathan Scott

University of Mississippi News

OXFORD, Miss. – A $150,000 grant to the University of Mississippi's Prison-to-College Pipeline Program will help expand course offerings and services to those looking to transform their lives during and after incarceration.

Analysis Of Crocetins And Safranal Variations In Saffron (Crocus Sativus) Stigma Samples And Dietary Supplements Using Hplc/Uhplc-Pda-Ms: Chemical Profiling And Chemometric Analysis Using Lc-Qtof, Kumar Katragunta, Bharathi Avula, Ya-Hong Wang, Roy Upton, Ikhlas A. Khan

Annual Poster Session 2023-2024

Saffron, the most expensive spice in the world, is comprised of dried and dark red stigma of Crocus sativus L. flowers of the Iridaceae family. It is mainly used as a spice for imparting color, fragrance, and flavor to food, but its medicinal and dyeing properties are also well known. In the United States, saffron products are used as dietary supplements for mood elevation, relaxation, weight loss, and to increase metabolism. This paper describes two analytical methods for the determination of crocetin esters, picrocrocin, and safranal in saffron samples and dietary supplements for inclusion in a monograph under development by …

World-Class Research An D Development Management; Customer And Supplier Value Chain; Strategic Management Guidelines, Society Of Management Accountants Of Canada, American Institute Of Certified Public Accountants (Aicpa), Australian Society Of Certified Practising Accountants

Guides, Handbooks and Manuals

No abstract provided.

Graduate School Newsletter Winter 2023-2204, Sandra Spiroff, Martha C. Helms

Newsletters of the Graduate School

No abstract provided.

Yes, And: Igniting Your Pedagogical Imagination, Emily Pitts Donahoe, Derek Bruff, Joshua Eyler, Liz Norell

Events

Have you ever attended a teaching workshop and thought, “That’s an interesting idea—but I don’t know how it would work in my class.” If so, this session is for you! In the first part of the workshop, we’ll present a teaching technique chosen at random. Our expert panelists will compete to see who can translate that teaching technique to their own discipline and course in the most creative way. In the second part of the workshop, attendees will have a chance to draw their own teaching technique from the hat and brainstorm about how they might apply it in their …

Issue 435: January 25-February 8, 2024, The Local Voice

The Local Voice

No abstract provided.

January 25, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Pharmacy Matters - December 2023/January 2024, University Of Mississippi. School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: "Pharmacy School Secures NASA Seed Grant Funding," "Students Selected for National Leaders Program for Community Pharmacy," "Professor Weighs in on Wise Use of Antibiotics," "Researchers Find Turmeric, Thyme Oils Repel Fire Ants," "University Launches New Cannabis, Dietary Supplements Graduate Program"

Es/Ph/Sra 511: Applied Statistics, Minsoo Kang

GMAS Course Syllabi

No abstract provided.

Ph 610: Biostatistics For Public Health Practice, Ruaa Al Juboori

GMAS Course Syllabi

No abstract provided.

Modified Loss Functions For Algorithmic Bias Mitigation, Christina Joy Trotter

Electronic Theses and Dissertations

Artificial intelligence and machine learning are becoming more present in everyday life. Training data distributions, amongst other variables, can cause these systems to be unfair. Users, as well as other individuals, may be negatively impacted. This work studies using modified loss functions to mitigate race and sex bias caused by data and models.

In the first experiment, the trade-off between fairness and accuracy when data is biased and unbiased is explored. A group risk function is introduced and used to create two versions of a modified loss function: Max Group Equity and Max Group Equality Binary Cross-Entropy (BCE). Both functions …

The Relationship Between Nutrient Intake And Performance Recovery In Ncaa Softball Athletes, Derionne Brooks

Electronic Theses and Dissertations

Collegiate athletes are faced with the challenge of maintaining optimal performance outcomes in spite of their demanding training schedules. As a result, athletes rely on recovery strategies such as nutrition and adequate sleep to optimize their recovery in these shortened windows. This study aimed to explore the relationship between dietary intake, sleep, and athletic performance in female collegiate athletes (N=27) using dietary recalls analyzed using the Nutrition Data System for Research, self-reported sleep data, and data collected using PERCH devices. Twenty-seven current members of a collegiate softball team participated in the data collection throughout their fall season (August – December). …

Crosscultural Backchannelling Responses Among Second Language Learners, Chien-Hui Hsu

Electronic Theses and Dissertations

Backchannel responses (Yngve, 1970) have always been an essential component of conversational interactions that facilitate speaker-listener engagement and mutual shaping of narratives (Bavelas et al., 2000). This study aims to investigate the cross-linguistic difference in backchannelling responses between Taiwan Mandarin and English (General American) second language (L2) learners, and how those differences might impact communication in a cross-cultural classroom. The current study examines 20 participants, ten each from Taiwan Mandarin speakers and American English speakers. Each speaker was observed in an online conversation to eliminate the influence of non-verbal cues such as gestures and facial expressions. The backchannelling responses they …

The Metaphysics Of Creaturely Love In The Philosophy Of Anne Conway, Jeremiah Joseph Langer

Electronic Theses and Dissertations

A common belief during the early modern period held that humans bear ethical relations only to creatures with whom we share the right kinds of similarity. A tradition attributed to René Descartes holds speciesist and anthropocentric views according to which nonhuman animals are mere automata who lack rational minds. Even Baruch Spinoza, who was much more radical in his Ethics, suggests creaturely similarity is restricted to beings with rationality. As such, Descartes and Spinoza conclude that lower beings cannot be morally evaluated for their actions and humans cannot be morally evaluated for their treatment of lower creatures. In her sole …

Bigger Than Bees: Victorian England’S Relationship To The Bee – Considering Symbolism And Understanding, Grace Jacqueline Kaim

Electronic Theses and Dissertations

The complex and beautiful relationship the people in Victorian England had to the bee is one that goes beyond ideas of politics and religion. This thesis will explore this relationship by utilizing print, ephemera, jewelry, and household items, to demonstrate how the representation and symbolism of the bee was recognized and cherished by Victorians. While bees did certainly have an intimate relationship to the areas of politics and religion, one that is acknowledged throughout this work, their connection to grander themes of introspection, industrialism, folklore, morality, and status helps us understand the Victorians on a deeper level.

De Novo Design Approaches Toward The Development Of Artificial Cu Proteins (Arcups) For Activation Of Small Molecules With Functional Relevance To Cu Monooxygenases, Divyansh Prakash

Electronic Theses and Dissertations

Metalloenzymes catalyze various redox reactions in biogeochemical cycles involved in energy conversion. Our research focuses on Cu-based metalloenzymes, which perform diverse functions in nature and play a crucial role in substrate activation, energy conversion such as oxidizing methane to methanol by particulate methane monooxygenases (pMMOs), and biomass degradation by lytic polysaccharide monooxygenases (LPMOs), useful in biofuel production. However, much is unknown about how the active site and secondary/tertiary-sphere interactions in these enzymes determine their function. De novo protein design enables the creation of simpler model systems that closely resemble the structure and function of native enzymes. Using de novo protein …

A Qualitative Examination Of The Interplay Of Attachment Styles, The Supervisory Relationship & Counseling Self-Efficacy, Kamiron Ball Tran

Electronic Theses and Dissertations

This phenomenological qualitative study explores the intricate dynamics between attachment styles, the supervisory relationship, and counseling self-efficacy among supervisory dyads in counseling. The findings reveal five themes: supervision is relational, supervision is a therapeutic space, security within supervision bolsters self-efficacy, supervision is a mirror for clinical practice, and the nuanced "both/and" nature of attachment and self-efficacy dynamics. This study addresses a gap in the literature by offering qualitative insights into the interplay of attachment styles, supervisory relationship, and counselor self-efficacy, thus contributing to a deeper understanding of the complexities within supervisory practices in counseling.

The Value Of Empathy For Teachers In Nontraditional Classrooms, Mindy Clair Waldrop

Electronic Theses and Dissertations

Little is known about the experience of teachers in nontraditional classrooms, particularly those in Juvenile Detention Centers (JDCs). Using the tenets of hermeneutic phenomenology this study interpreted the lived experience of teachers in nontraditional classrooms. Hermeneutic principles involve using texts, including interview transcripts, to develop understanding and interpret meaning. Following interviews with teachers currently practicing in the JDC nontraditional classroom setting, the researcher engaged in the hermeneutic circle of understanding, which requires an ongoing commitment to the attitude of hermeneutic phenomenology and reflection (Alsaigh & Coyne, 2021). Four themes emerged as significant to the experience of teachers and their use …