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Formulation And Characterization Of Quetiapine Fumarate Floating Bioadhesive Tablets, Ajay Reddy Kolipaka Jan 2024

Formulation And Characterization Of Quetiapine Fumarate Floating Bioadhesive Tablets, Ajay Reddy Kolipaka

Electronic Theses and Dissertations

Quetiapine fumarate (QF) is an antipsychotic drug, and it has a plasma half-life of 6 hours. The chemical structure of QF has nitrogen groups making it highly soluble in acidic pH and slightly soluble in alkaline pH. This study aimed to develop the QF gastroretentive tablets by TSMG technology comprising floating and mucoadhesive approach by using different viscosity grades of HPMC to improve absorption by prolonging its gastric residence time. The floating tablets were prepared using the Twin screw melt granulation (TSMG) technology, and the impact of polymer concentration and viscosity grades of HPMC on the floating ability and drug …


Examining The Relationship Between Toddlers’ Sleep Patterns, Negative Parenting, And Executive Function, Morgan Elizabeth Harris Jan 2024

Examining The Relationship Between Toddlers’ Sleep Patterns, Negative Parenting, And Executive Function, Morgan Elizabeth Harris

Electronic Theses and Dissertations

Negative parenting can often be described as having three domains (i.e., laxness, verbosity, and over-reactivity, Arnold et al., 1993; Rhoades & O’Leary, 2007), which may have relations to toddlers’ behaviors, like executive function (EF) and sleep. However, this field is understudied, especially in early childhood development. One possible explanation for the lack of research in this field is that it can be difficult to study executive function in toddlers due to variability in the stability of regulatory behaviors and emerging regulatory abilities at this age range. Although positive sleep patterns (e.g., quality and quantity) have been linked to executive function, …


Indirect And Direct Pathways Of Migratory Shorebird Effects On Nitrogen Cycling Within Temporarily Flooded Agricultural Fields, Victoria Blocker Jan 2024

Indirect And Direct Pathways Of Migratory Shorebird Effects On Nitrogen Cycling Within Temporarily Flooded Agricultural Fields, Victoria Blocker

Electronic Theses and Dissertations

The global human population continues to grow exponentially, and agriculture will need to become more productive to meet growing food demands. Humans also need clean water and other services that ecosystems provide. This requires future agriculture production to reduce environmental and wildlife impacts through improved efficiencies and best management practices. Migratory shorebirds rely on wetlands throughout North and South America as stopover habitat for rest and refueling during migration. Temporarily flooded farmlands in the Mississippi Delta have proven to be beneficial locations for shorebirds during migrations along the central flyway. This conservation practice also enhances wetland properties that promote excess …


Research News, Publications, 2024, Volume 3, Soumyajit Majumdar Jan 2024

Research News, Publications, 2024, Volume 3, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of July 1 through September 30, 2024.


The Relationship Between Aim Pathways Professional Development, Teachers’ Sense Of Efficacy For Literacy Instruction, And Literacy Knowledge, Among K-3 Teachers, Shakita Bagwell Jan 2024

The Relationship Between Aim Pathways Professional Development, Teachers’ Sense Of Efficacy For Literacy Instruction, And Literacy Knowledge, Among K-3 Teachers, Shakita Bagwell

Electronic Theses and Dissertations

Teaching reading has been an ongoing challenge for many educators across the United States. Numerous studies suggest that teachers feel they were not adequately prepared to teach reading and have low efficacy in delivering literacy instruction. Teaching reading requires educators to be knowledgeable about the alphabetic principle, decoding new words, and how the brain learns to read. This exploratory study aimed to investigate the relationship between AIM Pathways Professional Development on teachers’ literacy efficacy and knowledge compared to teachers who did not receive the professional development. A survey was administered to eighty-eight teachers in Mississippi Literacy Support Schools. Multidimensional scaling …


More Than A Feeling: Materializing Sympathy In Nineteenth-Century American Literature, Kathleen Downes Jan 2024

More Than A Feeling: Materializing Sympathy In Nineteenth-Century American Literature, Kathleen Downes

Electronic Theses and Dissertations

“More than a Feeling: Materializing Sympathy in Nineteenth-Century American Literature” breaks from a long tradition of criticism that only considers the nineteenth-century belief that sympathy was a benevolent, voluntary, imaginative act of feeling that maintains moral rectitude through the identification of suffering with others. In this context, sympathy is primarily defined as identificatory sympathy. “More than a Feeling” expands the definition of sympathy in the nineteenth century as also something that could be atmospherically communicated, transmitting good or bad feeling, and thus affecting and infecting those around them. This other form of sympathy, which for this project I term “effluvial …


Montesquieu: The Nature Of L’Esprit Des Lois, Christian Jax Murray Jan 2024

Montesquieu: The Nature Of L’Esprit Des Lois, Christian Jax Murray

Electronic Theses and Dissertations

When Baron de Montesquieu received a copy of his L’Esprit des lois, he was horrified by the total removal and reorganization of critical parts of his text, changed ideas, and an abnormal amount of printing errors in his work. While he saw these issues hindering the reception of his work, this thesis argues that the chaos of the text, in both its style and publication, made the book more popular instead of hindering it. Montesquieu, his editor, and his publisher constructed a new kind of text that was broad in its subject matter and ambiguous in its meaning where its …


Investigation Of Evolution In Fungal Traits At Multiple Genetic Scales, Brooke Allen Jan 2024

Investigation Of Evolution In Fungal Traits At Multiple Genetic Scales, Brooke Allen

Electronic Theses and Dissertations

The study of fungal traits is critical for understanding community assembly and ecosystem function, as traits related to resource acquisition, enemy avoidance, and stress tolerance link fungi to their ecological roles. Symbiotic relationships, such as those between ectomycorrhizal (EcM) fungi and their host plants, greatly influence fungal traits and play a key role in fungal evolution. In this study, we addressed the evolution of EcM fungal traits, particularly biosynthetic gene clusters (BGCs), at multiple genetic scales, including individual genes, genotypes within populations, and a broader phylogenetic perspective across the fungal kingdom. First, we surveyed the diversity of BGCs in native …


Tidal Perturbations Of Kerr Spacetime And Their Impact On Orbits, L. Joseph Rivest Jan 2024

Tidal Perturbations Of Kerr Spacetime And Their Impact On Orbits, L. Joseph Rivest

Electronic Theses and Dissertations

I develop a software package to produce and analyze tidally perturbed geodesics in a Kerr background spacetime. Though my simulations do not include radiation reaction, they are a good proxy for Extreme Mass-Ratio Inspirals (EMRI) in a perturbing environment. The goal of this work is to categorize cases in which perturbations are likely to bias Gravity Wave (GW) signals detected by the Laser Interferometer Space Antenna (LISA) strongly enough to require additional modeling. I limit my investigation to static perturbation fields. I perform metric reconstruction in the Geroch-Held-Penrose (GHP) formalism followed by a novel approach to the derivation of the …


Dunc13 Isoforms, Rim, And Rab3 Differentially Modulate Ethanol Sedation Sensitivity In Drosophila Melanogaster., Gaurav Shrestha Jan 2024

Dunc13 Isoforms, Rim, And Rab3 Differentially Modulate Ethanol Sedation Sensitivity In Drosophila Melanogaster., Gaurav Shrestha

Electronic Theses and Dissertations

Dunc13 is a Drosophila active zone protein homologous to the mammalian Munc13that interacts with RIM and Rab3 as a heterotrimer. Alcohol binds to the C1 domain of Dunc13/Munc13 and inhibits its ability to bind to Diacylglycerol, inhibiting neuronal signaling. The genetic reduction of Dunc13 activity in the Dunc13P84200/+ heterozygotes induces a state in flies that mimics alcohol tolerance, evidenced by increased self-administration, and behavioral, physiological, and molecular resistance. This includes changes in the expression of key synaptic proteins, such as decreased expression of Dunc13 and Syb mRNA, and increased expression of Rim and Rab3 4hrs after ethanol exposure. Dunc13 has …


Shape-Shifting In Literary Commemorations To Emmett Till, Chase Almquist Browning Jan 2024

Shape-Shifting In Literary Commemorations To Emmett Till, Chase Almquist Browning

Electronic Theses and Dissertations

Emmett Till remains a prominent figure in African American literature and culture. Police and vigilante violence in the twenty-first century against Black American men, women, and children has provoked political and artistic comparisons between contemporary instances of anti-Black violence and the event of Till’s kidnapping and murder. This thesis recognizes these comparisons and argues for a reorientation of critical and popular attention within the ongoing project of commemorating Till through the genres of memoir, poetry, and fiction. With the publication of Mamie Till-Mobley’s memoir Death of Innocence in 2003, I argue that this text establishes a memorial baseline for the …


Effects Of Multiple Stressors On Pseudomonas Fluorescens Over Short And Long Timescales, Parisa Burchfield Jan 2024

Effects Of Multiple Stressors On Pseudomonas Fluorescens Over Short And Long Timescales, Parisa Burchfield

Electronic Theses and Dissertations

Stressors are ubiquitous factors in biological systems that result in deviations from an organism's optimal physiological state, potentially causing fitness decreases. Stressors can be biotic (e.g., predators, parasites, competitors) or abiotic (e.g., pH changes, temperature, environmental toxins). Persistent stress can lead to population declines unless organisms respond through mechanisms such as evolutionary adaptation. Experimental evolution with microorganisms, particularly bacteria, is a powerful method for studying these phenomena due to their short generation times, large populations, as well as the ability to control their environment, and freeze and revive populations. Bacteria-phage systems, such as Pseudomonas fluorescens SBW25 and its lytic phage …


Glycopolymeric Nanoparticles Enrich Less Immunogenic Protein Corona And Improve Tumor Delivery Compared To Pegylated Nanoparticles, Kenneth Ryan Hulugalla Jan 2024

Glycopolymeric Nanoparticles Enrich Less Immunogenic Protein Corona And Improve Tumor Delivery Compared To Pegylated Nanoparticles, Kenneth Ryan Hulugalla

Electronic Theses and Dissertations

Nanoparticles (NPs) offer significant promise as drug delivery vehicles; however, their in vivo efficacy is often hindered by the formation of a protein corona (PC), which influences key physiological responses such as blood circulation time, biodistribution, cellular uptake, and intracellular localization. Understanding NP-PC interactions is crucial for optimizing NP design for biomedical applications. Traditional approaches have utilized hydrophilic polymer coatings like polyethylene glycol (PEG) to resist protein adsorption, but glycopolymer-coated nanoparticles have emerged as superior alternatives due to their biocompatibility and ability to reduce the adsorption of highly immunogenic proteins. In this study, we synthesized and characterized glycopolymer-based poly[2(diisopropylamino)ethyl methacrylate-b-poly(methacrylamidoglucopyranose) …


From Pixels To Strings: Efficient String Art Creation Leveraging Greedy Algorithm, Ashraya Joshi Jan 2024

From Pixels To Strings: Efficient String Art Creation Leveraging Greedy Algorithm, Ashraya Joshi

Electronic Theses and Dissertations

This thesis optimizes String Art generation using advanced algorithms. String art is a technique that creates visual artworks composed of straight lines of strings tensioned between pins distributed on a canvas. Initially employing the Hough Transform, issues such as computational complexity and edge detection inaccuracies led to adopting a Greedy Algorithm. This algorithm iteratively enhances visual similarity between the string art and the original image by reducing the difference between pixel intensities between them, significantly improving quality and efficiency. Integrating non-photorealistic rendering techniques, the study ensures smoother and more coherent lines. The study demonstrates the improvements with different quantitative metrics. …


Temperamental Fear As A Vulnerability Factor For Posttraumatic Stress Symptoms: An Examination Of Fight, Flight, Freeze Using A Trauma Film Paradigm, Jaime P. Murtagh Jan 2024

Temperamental Fear As A Vulnerability Factor For Posttraumatic Stress Symptoms: An Examination Of Fight, Flight, Freeze Using A Trauma Film Paradigm, Jaime P. Murtagh

Electronic Theses and Dissertations

Fear is often the primary emotion associated with anxiety and stress-related disorders with research suggesting that the expression of fear varies greatly between individuals and has been hypothesized to be associated with differences in behavioral inhibition, personality, as well as temperament. One theory which has been used to conceptualize variations in temperament is the reinforcement sensitivity theory which consists of the behavioral inhibition system (BIS), behavioral approach system (BAS), and the fight, flight, freeze system (FFFS), with the latter being of particular interest in posttraumatic stress disorder (PTSD). Variations in FFFS sensitivity has been linked to variations in psychopathology with …


Do Storytelling And Survival Processing Have Additive Effects On Recall Performance?, Zoe Helena Fischer Jan 2024

Do Storytelling And Survival Processing Have Additive Effects On Recall Performance?, Zoe Helena Fischer

Electronic Theses and Dissertations

Both survival processing and storytelling have been shown to enhance memory performance relative to control conditions. We examined the extent to which combining these two techniques improves participants’ memory abilities relative to comparable control conditions. In one experiment, participants (n = 100) were randomly assigned to write sentences using unrelated common nouns in a sentence creation control, storytelling, survival, or survival plus storytelling condition. Participants who were instructed to write a story about survival were predicted to remember more words on a subsequent free recall test than participants in the other conditions. Mechanistically, we predict that combining predominantly item-specific processing …


Applying Dynamics And Geophysical Methods To Hawaiian Volcanic Terrains And Lava Flows, Brody K. Conner Jan 2024

Applying Dynamics And Geophysical Methods To Hawaiian Volcanic Terrains And Lava Flows, Brody K. Conner

Electronic Theses and Dissertations

Presented here is the culmination of research spurred by a month-long field expedition to the windward side of the Big Island of Hawai’i during July and August 2023. During this expedition, two ground-penetrating radar units, a Mala GX 160 MHz antenna and a Crossover 1760 dual frequency antenna, were used to survey the basaltic, volcanic landscapes of Mauna Loa and Kīlauea. Post-eruptive digital elevation models of the Ahu’ailā’au (2018 Lower Puna) Eruption and Quantum Geographic Information Systems were used in tandem with GPR Insights software to provide a thorough picture of the surface and subsurface lava flows from Ahu’ailā’au. Using …


"Waiting By The Shores", Emily Suh Dec 2023

"Waiting By The Shores", Emily Suh

Landshark Literary Review

No abstract provided.


Weeding Do's And Don'ts (Concurrent Session, Block A), Erica Jones, Elizabeth Simmons Dec 2023

Weeding Do's And Don'ts (Concurrent Session, Block A), Erica Jones, Elizabeth Simmons

School Library Symposium

Learn how to tackle your next weeding project with suggestions for “do’s and don’ts” in a time of censorship with Elizabeth Simmons, Instructional Materials and Library Media Director from the Office of Elementary Education and Reading at the Mississippi Department of Education, and Erica Jones, Oxford Early Childhood Center Librarian.


Laudato Si' And The Christian Ethic, Brandon Kriplean Dec 2023

Laudato Si' And The Christian Ethic, Brandon Kriplean

Venture: The University of Mississippi Undergraduate Research Journal

Christianity, specifically Catholicism, is an inherently anthropocentric religion, with humans having the most dignity of all mortal creatures due to their divine image. However, what does such a lofty view of humanity mean for the current environmental crises? Are Christianity and environmental stewardship mutually exclusive paradigms? Pope Francis has sought to maintain human dignity while at the same time encouraging the Church to recognize that the environment, as God’s creation, is not to be exploited. In other words, an anthropocentric perspective does not equal a disregard for other aspects of creation. His 2015 landmark encyclical, Laudato Si’, sought to highlight …


At The Intersection Of Functionality And Beauty: A Study Of The Carrara Herbal, Anna Grace Robinson Dec 2023

At The Intersection Of Functionality And Beauty: A Study Of The Carrara Herbal, Anna Grace Robinson

Venture: The University of Mississippi Undergraduate Research Journal

The Carrara Herbal is a manuscript that sits at the cusp between medieval and early Renaissance work in Padua, Italy. With medical “simples,” or singular ingredients to be combined, as its primary focus, the Herbal is heavily illustrated and illuminated (the process of decorating a manuscript with color and even precious metals like gold), demonstrating the commissioner’s intentions and establishing him as a leader in the field of botanical medical knowledge. However, the intent and practical use seem to be at odds in the case of the Carrara Herbal. As six centuries passed, the manuscript was actively used and revised …


Issue 432: November 30-December 14, 2023, The Local Voice Nov 2023

Issue 432: November 30-December 14, 2023, The Local Voice

The Local Voice

No abstract provided.


Effect Of Ploidy On Salinity And Temperature Tolerance In Early Life Stages Of The Eastern Oyster (Crassostrea Virginica), Christian Boudreaux, Jessica Pruett, Alexz Carpenter, Kristie Willett, Deborah Gochfeld Nov 2023

Effect Of Ploidy On Salinity And Temperature Tolerance In Early Life Stages Of The Eastern Oyster (Crassostrea Virginica), Christian Boudreaux, Jessica Pruett, Alexz Carpenter, Kristie Willett, Deborah Gochfeld

Honors Theses

The U.S. Gulf of Mexico contains the largest remaining wild oyster fishery in the world, but populations have declined in recent decades. A growing interest in off-bottom aquaculture that relies on triploid eastern oysters (Crassostrea virginica) has emerged in the Gulf region, yet these faster growing oysters suffer high mortality as adults during low salinity events (< 5 ppt) in warmer summer months. The combined effects of salinity and temperature stressors on early life stages of triploid oysters are unknown. Early life stages are particularly crucial to understand because triploid oysters do not occur naturally and must be reared in hatchery settings, requiring appropriate water conditions to yield the greatest survival and growth. Thus, we tested the effects of different temperatures (28oC and 32oC) and salinities (5, 10, and 15 ppt) on diploid and triploid oysters at three critical production stages: veliger, pediveliger, and spat. Veliger survival was significantly lower for triploids relative to diploid oysters at all experimental conditions, but triploid veligers had faster growth than diploids at 32oC and 15 ppt. Pediveliger settlement was not affected by ploidy type and only reduced at high temperature (32oC) and the lowest salinity (5 ppt). Diploid spat showed highest survival at 28oC and 15 ppt, while triploids survived best at 32oC and 15 ppt. Triploid spat attained greater shell height compared to diploids in our 6-day exposures, but growth decreased for both ploidies at lower salinities. At the salinity and temperature levels examined, diploid early life stages performed best at 28oC and 15 ppt, whereas triploids were more successful at 32oC and 15 ppt. A broader understanding of the combined effects of environmental stressors will improve the success of hatchery production yields and the resulting economic and environmental benefits of the oyster industry.


175th Anniversary Commemoration Remarks By Dr. Kathryn Mckee, Kathryn Mckee Nov 2023

175th Anniversary Commemoration Remarks By Dr. Kathryn Mckee, Kathryn Mckee

175th Anniversary Celebration

Speech given by Kathryn McKee, director, Center for the Study of Southern Culture and McMullan Professor of Southern Studies and Professor of English, during the 175th anniversary of the University of Mississippi celebration. Presented Monday, November 6, 2023 at 1:00 PM on the Lyceum steps.


Issue 430: November 2-16, 2023, The Local Voice Nov 2023

Issue 430: November 2-16, 2023, The Local Voice

The Local Voice

No abstract provided.


November 2, 2023, The Daily Mississippian Nov 2023

November 2, 2023, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Doing Oral History As Public Anthropology, Helen A. Regis Nov 2023

Doing Oral History As Public Anthropology, Helen A. Regis

Southern Anthropologist

Doing Oral History engages students as co-researchers in a community-engaged oral history project begun in 2011. Supported by a research partnership between a faculty member, a university oral history center, and a non-profit archive, the course engages learners in the exploration of a festival and its communities. Through oral histories with long-time festival workers, artists, staff, volunteers, and neighbors, we contribute to expanding the history of a festival and the social movements that have shaped it. We also consider the ways in which diverse festival workers come to feel a part of a community centering African American working-class folk, cultures, …


Standing Together Against Silencing: Anthropology As Inclusive Public History In The Anti-Crt Legislative Era, Ann E. Kingsolver, Elena Sesma Nov 2023

Standing Together Against Silencing: Anthropology As Inclusive Public History In The Anti-Crt Legislative Era, Ann E. Kingsolver, Elena Sesma

Southern Anthropologist

The authors – a high school student, undergraduate and graduate students, and Anthropology Department faculty members at the University of Kentucky – discuss ways that existing ethnographic, archival, and archaeological data can be explored with new analytical lenses to contribute to public history centering voices and perspectives that have been silenced and marginalized in dominant historical narratives. This is argued to be a vital pedagogical project in secondary and postsecondary educational as well as inclusive community discussions, given the current legislative environment across a number of states in the southeastern US that discourages the teaching and even availability of texts …


10.30.2023 Orsp Connect, Liz Williamson Oct 2023

10.30.2023 Orsp Connect, Liz Williamson

ORED Newsletter

No abstract provided.


Issue 429: October 19-November 2, 2023, The Local Voice Oct 2023

Issue 429: October 19-November 2, 2023, The Local Voice

The Local Voice

No abstract provided.