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Meet Glenn Schove, March's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

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Issue 323: March 21-April 4, 2019, The Local Voice

The Local Voice

No abstract provided.

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March 7, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

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Tissue-Specific Transcriptome Analysis Reveals Candidate Genes For Terpenoid And Phenylpropanoid Metabolism In The Medicinal Plant Ferula Assafoetida, Hajar Amini, Mohammad Reza Naghavi, Tong Shen, Yanhong Wang, Jaber Nasiri, Ikhlas A. Khan, Oliver Fiehn, Philipp Zerbe, Julin N. Maloof

Faculty and Student Publications

© 2019 ABRF. Methionine oxidation plays a critical role in many processes of biologic and biomedical importance, including cellular redox responses and stability of protein pharmaceuticals. Bottom-up methods for analysis of methionine oxidation can suffer from incomplete sequence coverage, as well as an inability to readily detect correlated oxidation between 2 or more methionines. However, the methodology for quantifying protein oxidation in top-down analyses is lacking. Previous work has shown that electron transfer dissociation (ETD)–based tandem mass spectrometry (MS/MS) fragmentation offers accurate and precise quantification of amino acid oxidation in peptides, even in complex samples. However, the ability of ETD-based …

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Physical Activity And Cognitive Function Among Older Adults With An Elevated Gamma Gap, Emily Frith, Paul D. Loprinzi

Faculty and Student Publications

© 2018 The Author(s) Published by S. Karger AG, Basel. Objective: An elevated gamma gap is indicative of high serum concentrations of globulin proteins, some of which elicit acute inflammatory responses. An impaired cognitive function has been linked to central and peripheral inflammation, while exercise is associated with protective, anti-inflammatory benefits. In this study, we evaluated whether the gamma gap is associated with cognitive function among older adults and whether physical activity is favorably associated with cognitive function among those with an elevated gamma gap. Materials and Methods: Data from the 1999-2002 National Health and Nutrition Examination Survey (NHANES) were …

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Not-For-Profit Entities, March 1, 2019; Audit And Accounting Guide, Pak-Aims (American Institute Of Management Sciences)

Industry Guides (AAGs), Risk Alerts, and Checklists

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Fungi In The Marine Environment: Open Questions And Unsolved Problems, Anthony Amend, Gaetan Burgaud, Michael Cunliffe, Virginia P. Edgcomb, Cassandra L. Ettinger, M. H. Gutiérrez, Joseph Heitman, Erik F.Y. Hom, Giuseppe Ianiri, Adam C. Jones, Maiko Kagami, Kathryn T. Picard, C. Alisha Quandt, Seshagiri Raghukumar, Mertixell Riquelme, Jason Stajich, José Vargas-Muñiz, Allison K. Walker, Oded Yarden, Amy S. Gladfelter

Faculty and Student Publications

© 2019 Amend et al. Terrestrial fungi play critical roles in nutrient cycling and food webs and can shape macroorganism communities as parasites and mutualists. Although estimates for the number of fungal species on the planet range from 1.5 to over 5 million, likely fewer than 10% of fungi have been identified so far. To date, a relatively small percentage of described species are associated with marine environments, with ~1,100 species retrieved exclusively from the marine environment. Nevertheless, fungi have been found in nearly every marine habitat explored, from the surface of the ocean to kilometers below ocean sediments. Fungi …

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Selective Inhibition Of Human Monoamine Oxidase B By Acacetin 7-Methyl Ether Isolated From Turnera Diffusa (Damiana), Narayan D. Chaurasiya, Jianping Zhao, Pankaj Pandey, Robert J. Doerksen, Ilias Muhammad, Babu L. Tekwani

Faculty and Student Publications

© 2019 John Wiley & Sons Ltd Background: Bodybuilding supplements can cause a profound cholestatic syndrome. Aim: To describe the drug-Induced liver injury network's experience with liver injury due to bodybuilding supplements. Methods: Liver injury pattern, severity and outcomes, potential genetic associations, and exposure to anabolic steroids by product analysis were analysed in prospectively enrolled subjects with bodybuilding supplement-induced liver injury with causality scores of probable or higher. Results: Forty-four males (mean age 33 years) developed liver injury with a median latency of 73 days. Forty-one per cent presented with hepatocellular pattern of liver injury as defined by the R …

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Meet Terry Blackmarr, February's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

No abstract provided.

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Antiplasmodial And Cytotoxic Cytochalasins From An Endophytic Fungus, Nemania Sp. Um10m, Isolated From A Diseased Torreya Taxifolia Leaf, Mallika Kumarihamy, Daneel Ferreira, Edward M. Croom, Rajnish Sahu, Babu L. Tekwani, Stephen O. Duke, Shabana Khan, Natascha Techen, N. P. Dhammika Nanayakkara

Faculty and Student Publications

© 2019 American Chemical Society and American Society of Pharmacognosy. Cranberry (Vaccinium macrocarpon) juice is traditionally used for the prevention of urinary tract infections. Human urine produced after cranberry juice consumption can prevent Escherichia coli adhesion, but the antiadhesive urinary metabolites responsible have not been conclusively identified. Adult female sows were therefore fed spray-dried cranberry powder (5 g/kg/day), and urine was collected via catheter. Urine fractions were tested for antiadhesion activity using a human red blood cell (A+) anti-hemagglutination assay with uropathogenic P-fimbriated E. coli. Components were isolated from fractions of interest using Sephadex LH-20 gel filtration chromatography followed by …

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Issue 321: February 21-March 7, 2019, The Local Voice

The Local Voice

No abstract provided.

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Predator Diet Affects Perceived Oviposition Site Quality For Mosquitoes, Brandon Mcdaniel

Honors Theses

Ovipositing freshwater organisms rely primarily on cues to determine site quality (Silberbush and Blaustein 2008) and to select an ideal habitat for their offspring (Resetarits 2014). Characteristics of high quality oviposition sites that yield the greatest fitness for offspring include the absence of predators and high resource availability that allows for optimal growth and development (Kershenbaum et al. 2012). It has been shown that predator presence is a large deterrent of oviposition due to threats of offspring survival, however, there is a little information about the predatory cues mosquitoes experience before ovipositing (Angelon and Petranka 2002). One hypothesis is that …

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Neuroscientist Is Keynote Speaker For Brain Awareness Week, Edwin B. Smith

University of Mississippi News

Vanderbilt assistant professor Erin Calipari to address opioid addiction

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Tribute To The Late Dr. Charles D. Hufford, Alice M. Clark

Faculty and Student Publications

© 2019 The Authors. Purpose: Δ9-Tetrahydrocannabinol-valine-hemisuccinate, a hydrophilic prodrug of Δ9-tetrahydrocannabinol, synthesized with the aim of improving the ocular bioavailability of the parent molecule, was investigated in a lipid-based nanoparticle dosage form for ocular delivery. Methods: Solid lipid nanoparticles (SLNs) of Δ9-tetrahydrocannabinol-valine-hemisuccinate and Δ9-tetrahydrocannabinol, along with a nanoemulsion of Δ9-tetrahydrocannabinol-valine-hemisuccinate, were tested for glaucoma management in a normotensive rabbit model by using a multiple-dosing protocol. Marketed formulations of timolol maleate and pilocarpine HCl were also tested for their pharmacodynamic profile, post-single dose administration. Results: A peak intraocular pressure (IOP) drop of 30% from baseline was observed in rabbits treated with …

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Issue 320: February 7-21, 2019, The Local Voice

The Local Voice

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February 7, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

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Mr. Burns' Examines Importance Of Stories In Everyday Life, Katherine Stewart

University of Mississippi News

Director promises a show 'like nothing you've ever seen before' in Ole Miss Theatre production

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Minimally Manipulative Method For The Expansion Of Human Bone Marrow Mesenchymal Stem Cells To Treat Osseous Defects, Logan M. Lawrence, Andrew Cottrill, Amrita Valluri, Gaetano Marenzi, Krista L. Denning, Jagan Valluri, Pier Paolo Claudio, James B. Day

Faculty and Student Publications

Copyright © 2019 Hamerly, Tweedell, Hritzo, Nyasembe, Tekwani, Nanayakkara, Walker and Dinglasan. Malaria is a major global health threat, with nearly half the world's population at risk of infection. Given the recently described delayed clearance of parasites by artemisinincombined therapies, new antimalarials are needed to facilitate the global effort toward elimination and eradication. NPC1161 is an 8-aminoquinoline that is derived from primaquine with an improved therapeutic profile compared to the parent compound. The (R)-(-) enantiomer (NPC1161B) has a lower effective dose that results in decreased toxic side effects such as hemolysis compared to the (S)-(+)-enantiomer, making it a promising compound …

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Prostate Cancer Disparity, Chemoprevention, And Treatment By Specific Medicinal Plants, Clement G. Yedjou, Ariane T. Mbemi, Felicite Noubissi, Solange S. Tchounwou, Nole Tsabang, Marinelle Payton, Lucio Miele, Paul B. Tchounwou

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Prostate cancer (PC) is one of the most common cancers in men. The global burden of this disease is rising. Its incidence and mortality rates are higher in African American (AA) men compared to white men and other ethnic groups. The treatment decisions for PC are based exclusively on histological architecture, prostate-specific antigen (PSA) levels, and local disease state. Despite advances in screening for and early detection of PC, a large percentage of men continue to be diagnosed with metastatic disease including about 20% of men affected with a high mortality …

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January 31, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

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Meet Vernita Ivy, January's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

No abstract provided.

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Issue 319: January 24-February 7, 2019, The Local Voice

The Local Voice

No abstract provided.

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Doctoral Candidate Earns Fellowship To Continue Literary Research, Michael Newsom

University of Mississippi News

Amber Hodge to continue dissertation work at University of Virginia's academic libraries

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Issue 318: January 10-24, 2019, The Local Voice

The Local Voice

No abstract provided.

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Meet Dewey Knight, December's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

No abstract provided.

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Giant Tortoise Genomes Provide Insights Into Longevity And Age-Related Disease, Víctor Quesada, Sandra Freitas-Rodríguez, Joshua Miller, José G. Pérez-Silva, Zi Feng Jiang, Washington Tapia, Olaya Santiago-Fernández, Diana Campos-Iglesias, Lukas F.K. Kuderna, Maud Quinzin, Miguel G. Álvarez, Dido Carrero, Luciano B. Beheregaray, James P. Gibbs, Ylenia Chiari, Scott Glaberman, Claudio Ciofi, Miguel Araujo-Voces, Pablo Mayoral, Javier R. Arango, Isaac Tamargo-Gómez, David Roiz-Valle, María Pascual-Torner, Benjamin R. Evans, Danielle L. Edwards, Ryan C. Garrick, Michael A. Russello, Nikos Poulakakis, Stephen J. Gaughran, Danny O. Rueda, Gabriel Bretones, Tomàs Marquès-Bonet

Faculty and Student Publications

© 2018, The Author(s), under exclusive licence to Springer Nature Limited. Giant tortoises are among the longest-lived vertebrate animals and, as such, provide an excellent model to study traits like longevity and age-related diseases. However, genomic and molecular evolutionary information on giant tortoises is scarce. Here, we describe a global analysis of the genomes of Lonesome George—the iconic last member of Chelonoidis abingdonii—and the Aldabra giant tortoise (Aldabrachelys gigantea). Comparison of these genomes with those of related species, using both unsupervised and supervised analyses, led us to detect lineage-specific variants affecting DNA repair genes, inflammatory mediators and genes related to …

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Gellan Gum Based Sol-To-Gel Transforming System Of Natamycin Transfersomes Improves Topical Ocular Delivery, Karthik Yadav Janga, Akshaya Tatke, Narendar Dudhipala, Sai Prachetan Balguri, Mohamed Moustafa Ibrahim, Doaa Nabih Maria, Monica M. Jablonski, Soumyajit Majumdar

Faculty and Student Publications

© 2019 John Wiley & Sons Ltd Aim: Mesophotic coral ecosystems (MCEs) are unique communities that support a high proportion of depth-endemic species distinct from shallow-water coral reefs. However, there is currently little consensus on the boundaries between shallow and mesophotic coral reefs and between upper versus lower MCEs because studies of these communities are often site specific. Here, we examine the ecological evidence for community breaks, defined here as species loss, in fish and benthic taxa between shallow reefs and MCEs globally. Location: Global MCEs. Time period: 1973–2017. Major taxa studied: Macrophytes, Porifera, Scleractinia, Hydrozoa, Octocorallia, Antipatharia and teleost …

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Hepatotoxicity Of A Cannabidiol-Rich Cannabis Extract In The Mouse Model, Laura E. Ewing, Charles M. Skinner, Charles M. Quick, Stefanie Kennon-Mcgill, Mitchell R. Mcgill, Larry A. Walker, Mahmoud A. Elsohly, Bill J. Gurley, Igor Koturbash

Faculty and Student Publications

© 2019 Xide Ye et al. Gastrodia elata Blume belongs to the Orchidaceae family. G. elata is often processed when used in traditional Chinese medicine (TCM). In the current study, a traditional processing method, known as "Jianchang Bang," was applied. Steamed and dried (S&D) G. elata was processed with ginger juice for up to 5 days (GEP5D). An UHPLC-MS/MS combined with a chemometric method was developed for the analysis of processed G. elata along with the raw material as well as steamed and dried G. elata. As a result, the primary marker compounds were identified with the aid of TOF-MS …

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Npc1161b, An 8-Aminoquinoline Analog, Is Metabolized In The Mosquito And Inhibits Plasmodium Falciparum Oocyst Maturation, Timothy Hamerly, Rebecca E. Tweedell, Bernadette Hritzo, Vincent O. Nyasembe, Babu L. Tekwani, N. P. Dhammika Nanayakkara, Larry A. Walker, Rhoel R. Dinglasan

Faculty and Student Publications

© 2019 by the authors. The goal of this study was to investigate the potential for a cannabidiol-rich cannabis extract (CRCE) to interact with the most common over-the-counter drug and the major known cause of drug-induced liver injury–acetaminophen (APAP)–in aged female CD-1 mice. Gavaging mice with 116 mg/kg of cannabidiol (CBD) [mouse equivalent dose (MED) of 10 mg/kg of CBD] in CRCE delivered with sesame oil for three consecutive days followed by intraperitoneally (i.p.) acetaminophen (APAP) administration (400 mg/kg) on day 4 resulted in overt toxicity with 37.5% mortality. No mortality was observed in mice treated with 290 mg/kg of …

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Actuopaleoichnology Of A Modern Bay Of Fundy Macro-Tidal Flat: Analogy With A Mississippian Tidal Flat Deposit (Hartselle Sandstone) From Alabama, Louis G. Zachos, Brian F. Platt

Faculty and Student Publications

Copyright 2019 Zachos and Platt Trace fossil zonation in the Hartselle Sandstone of Mississippian age (Chesterian: Visean-Serpukhovian) exposed on Fielder Ridge, Alabama is compared with modern macro-tidal flat ichnocoenoses on the Bay of Fundy at Lubec, Maine, and demonstrated to be analogous by sedimentologic and ichnotaxonomic criteria. The modern flat has minimal influence from either waves or freshwater influx, and can be divided into five distinct ichnocoenoses, characterized by surface traces (epichnia) and four sedimentologic facies defined by gross grain texture or hydrodynamic characteristics, but lacking significant surface traces. Several characteristics of tidal flat deposits in a fetch-limited, marine (i.e., …

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Full-Text Articles in Entire DC Network

Meet Glenn Schove, March's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

Issue 323: March 21-April 4, 2019, The Local Voice

The Local Voice

March 7, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

Tissue-Specific Transcriptome Analysis Reveals Candidate Genes For Terpenoid And Phenylpropanoid Metabolism In The Medicinal Plant Ferula Assafoetida, Hajar Amini, Mohammad Reza Naghavi, Tong Shen, Yanhong Wang, Jaber Nasiri, Ikhlas A. Khan, Oliver Fiehn, Philipp Zerbe, Julin N. Maloof

Faculty and Student Publications

Physical Activity And Cognitive Function Among Older Adults With An Elevated Gamma Gap, Emily Frith, Paul D. Loprinzi

Faculty and Student Publications

Not-For-Profit Entities, March 1, 2019; Audit And Accounting Guide, Pak-Aims (American Institute Of Management Sciences)

Industry Guides (AAGs), Risk Alerts, and Checklists

Faculty and Student Publications

Selective Inhibition Of Human Monoamine Oxidase B By Acacetin 7-Methyl Ether Isolated From Turnera Diffusa (Damiana), Narayan D. Chaurasiya, Jianping Zhao, Pankaj Pandey, Robert J. Doerksen, Ilias Muhammad, Babu L. Tekwani

Faculty and Student Publications

Meet Terry Blackmarr, February's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

Antiplasmodial And Cytotoxic Cytochalasins From An Endophytic Fungus, Nemania Sp. Um10m, Isolated From A Diseased Torreya Taxifolia Leaf, Mallika Kumarihamy, Daneel Ferreira, Edward M. Croom, Rajnish Sahu, Babu L. Tekwani, Stephen O. Duke, Shabana Khan, Natascha Techen, N. P. Dhammika Nanayakkara

Faculty and Student Publications

Issue 321: February 21-March 7, 2019, The Local Voice

The Local Voice

Predator Diet Affects Perceived Oviposition Site Quality For Mosquitoes, Brandon Mcdaniel

Honors Theses

Neuroscientist Is Keynote Speaker For Brain Awareness Week, Edwin B. Smith

University of Mississippi News

Tribute To The Late Dr. Charles D. Hufford, Alice M. Clark

Faculty and Student Publications

Issue 320: February 7-21, 2019, The Local Voice

The Local Voice

February 7, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

Mr. Burns' Examines Importance Of Stories In Everyday Life, Katherine Stewart

University of Mississippi News

Minimally Manipulative Method For The Expansion Of Human Bone Marrow Mesenchymal Stem Cells To Treat Osseous Defects, Logan M. Lawrence, Andrew Cottrill, Amrita Valluri, Gaetano Marenzi, Krista L. Denning, Jagan Valluri, Pier Paolo Claudio, James B. Day

Faculty and Student Publications

Prostate Cancer Disparity, Chemoprevention, And Treatment By Specific Medicinal Plants, Clement G. Yedjou, Ariane T. Mbemi, Felicite Noubissi, Solange S. Tchounwou, Nole Tsabang, Marinelle Payton, Lucio Miele, Paul B. Tchounwou

Faculty and Student Publications

January 31, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

Meet Vernita Ivy, January's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

Issue 319: January 24-February 7, 2019, The Local Voice

The Local Voice

Doctoral Candidate Earns Fellowship To Continue Literary Research, Michael Newsom

University of Mississippi News

Issue 318: January 10-24, 2019, The Local Voice

The Local Voice

Meet Dewey Knight, December's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

Faculty and Student Publications

Gellan Gum Based Sol-To-Gel Transforming System Of Natamycin Transfersomes Improves Topical Ocular Delivery, Karthik Yadav Janga, Akshaya Tatke, Narendar Dudhipala, Sai Prachetan Balguri, Mohamed Moustafa Ibrahim, Doaa Nabih Maria, Monica M. Jablonski, Soumyajit Majumdar

Faculty and Student Publications

Hepatotoxicity Of A Cannabidiol-Rich Cannabis Extract In The Mouse Model, Laura E. Ewing, Charles M. Skinner, Charles M. Quick, Stefanie Kennon-Mcgill, Mitchell R. Mcgill, Larry A. Walker, Mahmoud A. Elsohly, Bill J. Gurley, Igor Koturbash

Faculty and Student Publications

Npc1161b, An 8-Aminoquinoline Analog, Is Metabolized In The Mosquito And Inhibits Plasmodium Falciparum Oocyst Maturation, Timothy Hamerly, Rebecca E. Tweedell, Bernadette Hritzo, Vincent O. Nyasembe, Babu L. Tekwani, N. P. Dhammika Nanayakkara, Larry A. Walker, Rhoel R. Dinglasan

Faculty and Student Publications

Actuopaleoichnology Of A Modern Bay Of Fundy Macro-Tidal Flat: Analogy With A Mississippian Tidal Flat Deposit (Hartselle Sandstone) From Alabama, Louis G. Zachos, Brian F. Platt

Faculty and Student Publications