Digital Commons Network^™

Correlation Of Inflammation In Arthritis With The Myelination In The Brain, Anna Spears

Honors Theses

This study was conducted to investigate whether the influence of arthritis has an effect on the cerebral white matter. The project was performed at the South Oxford Campus, where diffusion tensor imaging (DTI) data was obtained from the Nathan Kline Institute-Rockland Sample (NKI- RS). Image processing was conducted using Functional Magnetic Resonance Imaging of Brain Software Library in which we obtained raw data to formulate Apparent Diffusion Coefficient (ADC), Axial Diffusivity (AD), Radial Diffusivity (RD), and Fractional Anisotropy. A one way Analysis of Covariance (ANCOVA) was performed to determine the significant difference between the history of arthritis on each of …

A Qualitative Exploration Of A Kung Fu Character-Based Intervention And Third-Grade Students’ Perceptions, Kameron Shook

Honors Theses

Students are experiencing higher levels of stress in and out of the twenty-first century classroom. Stress can affect a student’s ability to interact with their peers, interact with their teacher, and interact with the material they are learning. Different interventions involving physical activities related to martial arts have been successful in improving student empathy and confidence in an anti-bullying intervention (Law, 2004; Rajan, 2015; Twemlow et al., 2008). However, few studies have addressed utilizing physically active standards-based lessons rooted in martial arts alongside focus vocabulary words as a means of developing the whole child, inclusive of the social, emotional, physical, …

Basements Below The Sanctuary: A Story Of The Church School, Rachel Winstead

Honors Theses

This is the story of belief in a southern Mississippi town and how that belief mirrors the national conservative counterrevolution that took shape at the same time. Hattiesburg’s segregation academy and church school were founded in the context of broader social movements. As the political power of the Citizen’s Council faltered and white moderates’ voices became louder, practical solutions to retain segregation within the boundaries of law grew to be the new focus of white communities. The conservative counterrevolution exploded in the South as Christian morality and “family values” became the rallying cry of former staunch segregationists and white moderates …

"Monsters In Suburbia": Women's Bodies, Monstrosity, And Motherhood In The Mere Wife, Claire M. Bonvillain

Honors Theses

This thesis explores themes of monstrosity in Maria Dahvana Headley's novel The Mere Wife in connection with issues of women's bodies and feminism. It analyzes prominent female characters in the novel and the relationships of their bodies to patriarchal authority, showing how and why bodies are deemed monstrous. It discusses the role that motherhood plays in patriarchal society, as well as explores alternatives that the novel offers to this system.

Examining The Possibilities Of Telehealth In Tallahatchie County, Taran Carrasco

Honors Theses

This thesis aims to analyze Tallahatchie County and determine the feasibility of establishing a telehealth program in the county. Telehealth is an evolving aspect in the medical field that incorporates technology with healthcare. This thesis used sociotechnical theory to explain how the feasibility of telehealth could be made more likely as the technology is used over time.Through interviewing UMMC telehealth directors, Tallahatchie Wellness center workers, and citizens of Charleston, this study aims to gauge professional and personal opinions on how feasible it would be to implement telehealth into the Charleston community, as well as how positively telehealth would be accepted …

A By Case Analysis Of Accounting Practices And Issues, John Walker

Honors Theses

The completion of my Thesis came as a result of enrolling in ACCY 420, a course taught by Dr. Victoria Dickinson, designed to provide accounting students with the opportunity to craft the thesis over the course of their junior year in college. This way, students are able to gradually write theses by completing several case studies designed to present students with challenging situations in which real-world accounting issues are explored. With the intensified recruiting process and the internship in the winter of senior year, this class was an excellent method to write the thesis during my junior year of college, …

Financial Accounting Through Case Studies, Erik Landry

Honors Theses

This thesis is a compilation of twelve case studies designed to promote an understanding of Generally Accepted Accounting Principles. Given the dynamic nature of accounting as a profession, it is imperative that students and professionals have a firm grasp of the foundational principles set forth by the Financial Accounting Standards Board. Each case provides insight related to the aforementioned standards and many corollary topics relevant to accounting professionals. The cases rely on both real and fictitious companies and their associated financial statements. The completion of these cases was of great benefit inasmuch as it provided the opportunity to examine essential …

Cooperating For Charity: The Effect Of Decentralization On French Associations, Ragan Ketrow

Honors Theses

This thesis explored the relationship between the decentralization laws of 1982 and 1983 in France and French associations as well as the resulting lack of exceptionalism in the French nonprofit sector. This thesis explores the claims of the French nonprofit scholar Edith Archambault as she argues that the steep rise in associations in France in the 1980s is due to the legal changes that occured during that same decade. In order to evaluate these claims, I used regression tests to compare the relationship between the growth of associations and other variants including economic growth, disposable income, and government expenditure. In …

Does It Get Any Worse Than Acne? It Does, Actually. An In-Depth Review Of Accutane’S Regulatory History., Bridget A. Betts

Honors Theses

Isotretinoin, most often recognized by the brand name Accutane®, is regarded by many patients and prescribers as the miracle cure for acne. Its unsurpassed efficacy is paired with serious risk of adverse events and birth defects, which poses ethical questions regarding its safety and necessity. Its regulatory history established precedent in Food and Drug Administration Risk Evaluation and Mitigation Strategies and brought awareness to the sharp dangers of teratogenic drug use.

This medication came as a breakthrough solution to patients that suffered years of unsuccessful regimens for the treatment of acne vulgaris. Some question the risk-benefit evaluation of such a …

Detection And Characterization Of Delta-9-Tetrahydrocannabinol And Novel Synthetic Cannabinoid Metabolites Using Human Liver Microsomes, Seema Murugan

Honors Theses

Marijuana and synthetic cannabinoids are the most commonly used and trafficked illicit drug. ∆⁹-tetrahydrocannabinol (THC) is the primary active compound in marijuana. Synthetic cannabinoids were created as a method to study the effects of cannabinoids on the endocannabinoid system, which consists of endogenous cannabinoids, cannabinoid receptors, and the synthetic and degrading enzymes responsible for the synthesis and degradation of endocannabinoids. Cannabinoids activate the same receptors as endocannabinoids. Synthetic cannabinoids gained popularity as recreational drugs due to their ability to avoid detection. Synthetic cannabinoids have been found to have a greater binding affinity to the cannabinoid CB₁ receptor …

The Effect Of Movement On Convergent And Divergent Thinking, Simmy Vig

Honors Theses

Research within the field of embodied cognition has primarily focused on the effect of bodily movement on convergent measures such as intelligence and memory, but few studies have explored movement’s effect on convergent thinking ability and divergent creative potential. This study aimed to investigate the effect of embodiment on convergent problem-solving (i.e., vocabulary and similarities tasks) and divergent creativity (i.e., Alternative Uses Task) through the movement conditions of constrained walking (i.e., path-walking) and unconstrained walking (i.e., roaming) in undergraduate college students. Participants simultaneously walked while completing the experimental tasks, and their responses were compared to those in the control (seated) …

Utilizing The Product Development Process To Bring An Idea From Concept To Production, Sydney Ferguson, Jackson Sneed

Honors Theses

The purpose of this thesis is to document and discuss the five-stage product development process starting with defining a problem and resulting in manufacturing a final product for sale as it was implemented in the Portable Fire Pit Center for Manufacturing Excellence Senior Capstone Project. This project was carried out over the course of the Fall 2019 and Spring 2020 semesters by a team consisting of three Undergraduate Mechanical Engineering majors and two Undergraduate Accountancy majors. The ultimate goal of the project was to carry out a full production run of the Portable Fire Pit outputting fifteen units meeting retail …

Synthesis And Characterization Of Transition Metal Scorpionate Complexes For Redox Shuttle Applications In Dye-Sensitized Solar Cells, Chase Lance

Honors Theses

Given the rising global energy demands, alternative renewable energy sources are currently being investigated. The most appealing renewable energy source is solar energy, and dye-sensitized solar cells (DSSCs) in particular are an attractive technology. DSSCs have traditionally utilized iodide/triiodide as the redox mediator couple, which exhibits high efficiencies and fast regeneration of the oxidized dye with little recombination. Recently, the use of alternative redox couples based on transition metal complexes has been studied as a promising substitute due to the tunable design of these complexes. In this study, tridentate tris(pyrazolyl)borate and tris(pyrazolyl)methane ligands with first-row transition metals were designed and …

An Assessment Of Herb-Drug Interaction Potential Of Two Herbs: Momordica Charantia And Phyllanthus Amarus, Faridah Salau

Honors Theses

The use of natural supplements alongside prescribed medications is on the increase. Thus, it is important to analyze different properties of herbal supplements that can be implicated in eliciting herb-drug interactions. The herb Momordica charnatia is used throughout the world for its antidiabetic properties, and the herb Phyllanthus amarus is used in tropical and subtropical areas of the world for its hepatoprotective properties. Pregnane X Receptor (PXR) activation capabilities of these herbs was measured using a reporter gene assay. Additionally, Cytochrome P450 (CYP) isoform induction potential for CYP1A2, CYP3A4, CYP2B6, and CYP2C9 was determined through an enzymatic assay in hepatic …

The Effects Of Acute Exercise And Psychological Stress On Episodic Memory, Lauren Koehler

Honors Theses

Research has suggested that exercise has an effect on memory function. Studies have also shown that exercise mitigates the effects of stress. The relationship between exercise and stress in regard to memory function is noteworthy. There has been little research on this relationship in young adults. This thesis discusses the effects of acute exercise on the episodic memory of young adults when they are exposed to a psychosocial stressor. The results of the research study show that acute aerobic exercise before memory encoding or consolidation was not associated with memory function after exposure to a stressor. Future research in this …

Synthesis Of Pharmaceutical And Personal Care Products And Pesticide Metabolites Of Environmental Concern, Isaiah Edwards

Honors Theses

Human pollution of aquatic environments by introduction of pharmaceutical and personal care products (PPCPs) as well as agrichemicals presents a grave threat to the health of aquatic organisms. Many of these chemicals not only exhibit toxicity to the species of complex ecosystems at various levels but also undergo metabolic transformation into moieties that have different and sometimes more potent physiochemical profiles. PPCP and pesticides as well as their metabolites impact organisms via a number of different mechanisms, with the most serious arguably being endocrine disruption. Two emerging pollutants, gemfibrozil and bifenthrin, possess naturally occurring metabolites that were determined to warrant …

The Hair You Wished To Comb, Sarah Barch

Honors Theses

This thesis is a collection of poems exploring gender and trauma in Greek mythology by retelling classical stories in a female voice.

The Embeddedness Of Racial Microaggressions In International Student Experiences At The University Of Mississippi, Morgan Blythe

Honors Theses

This study explores the lived experiences of international students at the University of Mississippi (UM). Using a phenomenological approach, the participants’ stories were understood and offered as a counter-narrative to existing literature dominated by White Americans. The interviews were processed through the lens of Critical Race Theory, specifically the microaggressions framework to account for modern-day racism as it evolves alongside culture. Twelve semi-structured interviews were conducted with international students at UM ranging from exchange to PhD candidates. These participants are from various countries around the globe, chosen through convenience sampling. The interviews were coded using NVivo12. The results of this …

"Army, I'M Home!": Digital Community And Mediated Intimacy In K-Pop Fandom, Olivia George

Honors Theses

In this paper, I argue that we should turn our attention to the affective labor in the pop culture industry in South Korea. Using the House of BTS event as a case study of K- Pop fandom, I will address the affective labor practices and its impacts in K-Pop fandom. Idol group BTS (방탄소년단) and their company Big Hit Entertainment are a particularly apt study for this choice because they deliberately adopt mediated intimacy as a marketing tactic, creating content outside of music and across social networking platforms that cater to fans’ desire to “know” and adore BTS members. In …

Design And Synthesis Of Novel Analogs As Potential Antitubercular Agents, Peggy Mccluggage

Honors Theses

Tuberculosis (TB) is an infectious, airborne disease which primarily infects the lungs. One-third of the world’s population is currently estimated to be infected with Mycobacterium tuberculosis (Mtb), the causative agent for TB [1]. Current treatment for this disease requires at least six months of taking multiple antibiotics with undesirable side effects [2]. Difficulty in complying to this regimen as well as the prevalence of HIV/AIDS has led to antimicrobial resistance seen in Mtb. In order to combat the Multi-Drug Resistant and Extensively-Drug Resistant strains of the disease-causing bacteria, preventative care and novel antibiotics are urgently needed [3]. The purpose for …

Multi-Generational Effects Of ∆9-Tetrahydrocannabinol Exposure On Gene Expression In Liver Tissue, Kayla Lovitt

Honors Theses

Cannabis is the most commonly used, cultivated, and trafficked illicit drug worldwide. Increased availability and acceptance of cannabis and cannabinoid-containing products provide the necessity for understanding how these substances influence aging. In this study, zebrafish (Danio rerio) were exposed to concentrations of Δ⁹-tetrahydrocannabinol (THC) (0.08, 0.4, 2 µM) during embryonic-larval development, the effects on aging were measured 30 months later and in the offspring of the exposed fish (F1 generation. We observed results indicating a biphasic and hormetic effect. Treatment with the lowest concentration of THC significantly increased egg production, while higher concentrations resulted in impaired …

Cell Proliferation And Viability Inhibition By Resveratrol On Breast Cancer Cell Lines, Kyle Ford Gordon Jr

Honors Theses

Antioxidants are well-known for their various health benefits. They are able to protect cells from being damaged by free radicals that are produced by vital biochemical processes. It has long been known that antioxidants are important in our everyday health, but their potential as disease preventers and potential therapeutic agents is a relatively new field of study. Resveratrol, a natural polyphenol and well-known antioxidant, is found in plants, fruits, and products derived from them, like red wine. Resveratrol has been shown to have various properties, including antiaging, anti-aggregation of platelets, anti-inflammatory, and anticancer activities. Because of their many health benefits, …

Accounting Research And Professional Development, Ragan Riley

Honors Theses

This paper is a compilation of various accounting studies assigned by Dr. Victoria Dickinson throughout a yearlong professional development course for accounting. During each of the twelve cases, the student was required to identify accounting principle problems within the cases, research proper accounting practices, and critically think through how these situations should have been handled in order for these companies to be in accordance with GAAP. There were also cases that facilitated decision making for students in their future career such as location decisions and articles regarding current accounting problems. This course allowed students to network with peers and accounting …

Acute Exercise On Memory Function: Open Vs. Closed Skill Exercise, Justin Cantrelle

Honors Theses

Accumulating research suggests that acute exercise may enhance memory function. Limited research, however, has evaluated whether the movement patterns of acute exercise may have a differential effect on memory. Such an effect is plausible, as research demonstrates that open-skilled exercise (e.g., racquetball) may have a greater effect on memory-related neurotrophins (e.g., brain-derived neurotrophic factors) when compared to closed-skilled exercise (e.g. treadmill exercise). A key distinction between open- and closed-skilled exercise is that open-skilled exercises are those that require an individual to react in a dynamic way to a changing, unpredictable environment. The purpose of this study was to evaluate whether …

Issue 347 H: May 7-13, 2020, The Local Voice

The Local Voice

No abstract provided.

Comparative Analysis Of The Results From The Ideal Gas Assumptions With More Rigorous Calculations From Pro/Ii Of The Production Of Pharmaceutical Grade Acetone, Soibifaa Frank-Briggs

Honors Theses

The Chemical engineering team was assigned by Landshark Inc to investigate the production of 30,000 tonnes/yr of pharmaceutical-grade acetone with a purity of 99.9 wt.% from the dehydrogenation of isopropanol (IPA). The team was tasked with determining the necessary process and unit operation criteria to ensure the economic feasibility of the proposed plant.

The major goal of this thesis is to provide a data comparison of the reactor in acetone production process when designed in Microsoft Excel and Pro/II. The first part of this thesis will introduce the base case briefly, transition into engineering optimizations and show the results found …

Backed By His Um Legacy Family - Journey To Commencement, Abigail Meisel

Journey to Commencement

Biology pre-med blazes his trail to a career as a physician

View Of Pakistani Residents Toward Coronavirus Disease (Covid-19) During A Rapid Outbreak: A Rapid Online Survey, Khezar Hayat, Meagen Rosenthal, Sen Xu, Muhammad Arshed, Pengchao Li, Panpan Zhai, Gebrehaweria Kassa Desalegn, Yu Fang

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: Coronavirus disease (COVID-19) is a deadly disease that is affecting most of the countries worldwide. Public understanding, including knowledge about signs and symptoms, mode of transmission, and hygiene of COVID-19, is vital for designing effective control strategies during a public health crisis. The current study is aimed at investigating the public’s perspective about COVID-19, including their knowledge, attitude, and practices. Methods: A rapid online survey comprising 22 items was administered during the rapid outbreak of COVID-19 in Pakistan. Questions were focused on the prevention, transmission, clinical features, and control of …

Unanticipated Stressful And Rewarding Experiences Engage The Same Prefrontal Cortex And Ventral Tegmental Area Neuronal Populations, Alberto Del Arco, Junchol Park, Bita Moghaddam

Faculty and Student Publications

© 2020 Del Arco et al. Brain networks that mediate motivated behavior in the context of aversive and rewarding experiences involve the prefrontal cortex (PFC) and ventral tegmental area (VTA). Neurons in both regions are activated by stress and reward, and by learned cues that predict aversive or appetitive outcomes. Recent studies have proposed that separate neuronal populations and circuits in these regions encode learned aversive versus appetitive contexts. But how about the actual experience? Do the same or different PFC and VTA neurons encode unanticipated aversive and appetitive experiences? To address this, we recorded unit activity and local field …

Pregnane Steroidogenesis Is Altered By Hiv-1 Tat And Morphine: Physiological Allopregnanolone Is Protective Against Neurotoxic And Psychomotor Effects, Jason Paris, Philippe Lière, Sarah Kim, Fakhri Mahdi, Meagen E. Buchanan, Sara R. Nass, Alaa N. Qrareya, Mohammed F. Salahuddin, Antoine Pianos, Neïké Fernandez, Zia Shariat-Madar, Pamela E. Knapp, Michaël Schumacher, Kurt F. Hauser

Faculty and Student Publications

Pregnane steroids, particularly allopregnanolone (AlloP), are neuroprotective in response to central insult. While unexplored in vivo, AlloP may confer protection against the neurological dysfunction associated with human immunodeficiency virus type 1 (HIV-1). The HIV-1 regulatory protein, trans-activator of transcription (Tat), is neurotoxic and its expression in mice increases anxiety-like behavior; an effect that can be ameliorated by progesterone, but not when 5α-reduction is blocked. Given that Tat's neurotoxic effects involve mitochondrial dysfunction and can be worsened with opioid exposure, we hypothesized that Tat and/or combined morphine would perturb steroidogenesis in mice, promoting neuronal death, and that exogenous AlloP would …