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Comparative Analysis Of Motors With Inner And Outer Reluctance Rotors And Pm Stators, Oluwaseun A. Badewa, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

This paper presents a comparison of special outer and inner reluctance rotor motor topologies with permanent magnet (PM) stators having toroidal AC windings. A systematic approach is taken to study and discuss the design geometries, the respective impact on performance, and adoption of technological advancements such as stator-only cooling and hair-pin winding for high slot fill factor. Parametric FEA models are developed for both topologies, and design of experiments (DoE)-based sensitivity analysis is used to study the effect of independent variables on specific performance metrics such as torque, motor loss, torque ripple, and power factor. Inner and outer rotor topologies …

Sensorless Control Of Low Inductance Coreless Afpm Machines For Fault-Tolerant Operation Of Propulsion Systems, Yaser Chulaee, Ali Mohammadi, Aaron M. Cramer, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

In motor-drive systems utilized in safety-critical applications and demanding conditions like electric aircraft propulsion systems, the reliability of the system is greatly affected by position sensors, given their susceptibility within the motor drive system. Consequently, there is a need to eliminate sensors in vector-controlled motor drives to decrease overall hardware complexity and expenses, bolster the mechanical durability and dependability of the drive system. In this paper, a fault-tolerant sensorless control system for low inductance coreless axial flux PM (AFPM) machines, integrated into electric aircraft propulsion systems, is introduced. The proposed control system spans a wide operating range, from zero to …

Fault-Tolerant Axial Flux Coreless Pm Machines With Independent Phase Modules, Yaser Chulaee, Ali Mohammadi, Dan M. Ionel, Matin Vatani

Electrical and Computer Engineering Graduate Research

In this paper, a fault-tolerant two-phase high power coreless axial flux PM (AFPM) machine with a modular structure is introduced. The performance of this machine, in terms of torque, power density, and efficiency, is compared with its three-phase counterpart configuration based on finite element analysis (FEA) and experimental results. The fault tolerance of these two configurations, considering the control systems, is also compared. A detailed power loss breakdown for the prototype two-phase and three-phase printed circuit board (PCB) stator coreless AFPM machines derived from experiments is presented, showcasing that the introduced fault-tolerant two-phase machine has comparable performance and efficiency, while …

High-Power Polyphase Pcb-Type Inductive Coupler For Wireless Electric Vehicle Charging, Donovin D. Lewis, Omer Onar, Lucas Gastineau, John F. Eastham, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

The cost and manufacturing difficulty of traditionally wound coils for wireless charging of electric vehicles has led to the exploration of alternative manufacturing for scalable deployment at a range of rated powers. A rotating-field polyphase wireless coupler is developed with balanced fully pitched coils which are not possible with conventional Litz wire. The usage of printed circuit board (PCB) technology is proposed for the innovative construction at large dimensions due to reduced cost, increased ease of manufacturability, and potential geometric customization compared to would coils. Design considerations specific to PCBs are detailed for wireless power transfer coils including advantages such …

Comparative Analysis Of Vernier Machines With Spoke, Surface Mounted, And Halbach Pm Rotors For In-Wheel Traction, Ali Mohammadi, Aaron M. Cramer, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Axial-flux Permanent Magnet (AFPM) machines are well-suited for in-wheel traction in electric vehicles due to their compact structure and higher torque density. This paper presents a large-scale design optimization of an axial-flux permanent magnet vernier machine (PMVM) of the MAGNUS type with a double stator configuration. The active stator features double layer wound coils, while the passive stator is unwound but has a similar profile. The reference design employs a rotor with permanent magnets (PMs) arranged in a spoke-type field intensifying pattern, providing high flux concentration. Design optimization was performed using 3-D electromagnetic Finite Element Analysis (FEA) and the Differential …

On The Optimal Design Of Coreless Afpm Machines With Halbach Array Rotors For Electric Aircraft Propulsion, Matin Vatani, Yaser Chulaee, Ali Mohammadi, David R. Stewart, John F. Eastham, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

This paper presents and evaluates the optimal design of a coreless axial flux permanent magnet (AFPM) motor for electric aircraft propulsion. Ferromagnetic cores are entirely removed from the machine’s structure to improve the specific power density and efficiency. An approach for envelope design optimization of the proposed motor is introduced, considering the polarity as an independent variable and employing an evolutionary algorithm and 3D Finite Element Analysis (FEA). In addition to the proposed electric motor’s electromagnetic performance, fault-tolerant capability and thermal management are considered in the optimization procedure. The optimization results and similar studies from power electronic and thermal management …

Association Of Circulating Markers Of Microbial Translocation And Hepatic Inflammation With Liver Injury In Patients With Type 2 Diabetes, Leila Gobejishvili, Vatsalya Vatsalya, Diana V. Avila, Yana B. Feygin, Craig J. Mcclain, Sriprakash Mokshagundam, Shirish Barve

Biostatistics Faculty Publications

Background: Virtually the entire spectrum of liver disease is observed in association with type 2 diabetes mellitus (T2DM); indeed, T2DM is now the most common cause of liver disease in the U.S. We conducted a pilot study to investigate the relevance of increased microbial translocation and systemic inflammation in the development of liver injury in patients with T2DM. Methods: Patients with T2DM (n = 17) and non-diabetic controls (NDC; n = 11) aged 25–80 yrs. participated in this study. Serum levels of endotoxin, calprotectin, soluble CD14 and CD163, and several inflammatory cytokines were measured. In addition to standard liver injury …

The Value Of Flexible Funding For Collaborative Biostatistics Units In Universities And Academic Medical Centres, Emily Slade, Sarah Jane K. Robbins, Kristen J. Mcquerry, Anthony A. Mangino

Biostatistics Faculty Publications

Collaborative biostatistics units within universities and academic medical centres operate under a wide range of different funding models; common to many of these models is the challenge of allocating time to activities that are not linked to a specific research project, such as professional development, mentorship and administrative tasks. The purpose of this paper is to describe a proposed model for ‘flexible funding’, that is, funding that is not linked to a specific research project, within a collaborative biostatistics unit and to detail the benefits and challenges associated with the proposed model. We present results from a qualitative study representing …

Lower Extremity Inter-Joint Coupling Angles And Variability During Gait In Pediatric Hypermobility Spectrum Disorder, Hyo Jung Jeong, Sergey Tarima, Anthony Nguyen, Anahita Qashqai, Michael Muriello, Donald Basel, Brooke A. Slavens

Biostatistics Faculty Publications

Complex musculoskeletal complications in children with hypermobility spectrum disorder (HSD) include pain, proprioception deficits, and joint instability, which may result in movement dysfunction during walking. However, no studies have explored the inter-joint coordination deficits in children with HSD. The purpose of this study was to determine the lower extremity inter-joint coupling angles, patterns, and variability during walking in children with HSD compared to children without HSD (non-HSD). Ankle, knee, and hip kinematics during the stance phase of walking in 18 children with HSD and 18 children without HSD were measured using three-dimensional motion analysis. Coupling angles, patterns, and variability of …

Working Well With Statisticians, Ryan A. Peterson, Emily Slade, Gina Maria Pomann, Walter T. Ambrosius

Biostatistics Faculty Publications

Statistical collaboration requires statisticians to work and communicate effectively with nonstatisticians, which can be challenging for many reasons. To identify common themes and lessons for working smoothly with nonstatistician collaborators, two focus groups of primarily academic collaborative statisticians were held. We identified qualities of collaborations that tend to yield fruitful relationships and those that tend to yield nothing (or worse, with one or both parties being dissatisfied). The initial goal was to share helpful knowledge and individual experiences that can facilitate more successful collaborative relationships for statisticians who work within academic statistical collaboration units. These findings were used to design …

Evaluation Of Ten Alternative Treatments For The Management Of Harlequin Bug (Murgantia Histrionica) On Brassica Crops, Sarah Clark, Ricardo Bessin, David J. Gonthier, Jonathan L. Larson

Entomology Faculty Publications

Harlequin bug (Murgantia histrionica) poses a significant threat to cruciferous vegetable crops, leading to economic losses and challenges in sustainable agriculture. This 2-year field study evaluated the efficacy of exclusion netting and selected biopesticides in controlling harlequin bug populations in a field-grown broccoli crop. Treatments included an untreated control, industry standards Azera and Entrust, and ProtekNet mesh netting. Additionally, three commercial essential oil treatments including Essentria IC-3, Nature-Cide, and Zero Tolerance were tested along with two bokashi fermented composting products BrewKashi and Oriental Herbal Nutrient (OHN). During both the first and second year of the study, none of the commercially …

Row Covers Limit Pests And Disease And Increase Profit In Organic Acorn Squash, Kathleen Fiske, Nieyan Cheng, Ryan Kuesel, Wendong Zhang, Ricardo Bessin, Mark A. Williams, David J. Gonthier

Entomology Faculty Publications

Organic cucurbit growers face many challenges to production including insect pests, insect-vectored diseases, and non-vectored diseases. While Organic Material Review Institute (OMRI) -listed pesticides underperform at suppressing pests and diseases, some alternative pest management strategies hold promise, but little research exists on their cost-effectiveness. We compared the efficacy of mesotunnel systems (nylon-mesh netting row covers deployed over bent metal hoops) and OMRI-listed pesticides (fungicides and insecticides) on acorn squash across 2 years. During the early part of the season, before row covers were removed for pollination, we found 1.7 (2020) and 0.3 (2021) times more cucumber beetles in the uncovered …

Snpaimer: R Package For Evaluating Ancestry Informative Marker Contributions In Non-Model Population Diagnostics, Kim L. Vertacnik, Oksana V. Vernygora, Julian R. Dupuis

Entomology Faculty Publications

Motivation: Single nucleotide polymorphism (SNP) markers are increasingly popular for population genomics and inferring ancestry for individuals of unknown origin. Because large SNP datasets are impractical for rapid and routine analysis, diagnostics rely on panels of highly informative markers. Strategies exist for selecting these markers, however, resources for efficiently evaluating their performance are limited for non-model systems.

Results: snpAIMeR is a user-friendly R package that evaluates the efficacy of genomic markers for the cluster assignment of unknown individuals. It is intended to help minimize panel size and genotyping effort by determining the informativeness of candidate diagnostic markers. Provided genotype data …

Shared Patterns Of Population Genomic Variation And Phenotypic Response Across Rapid Range Expansions In Two Invasive Lady Beetle Species, Angela G. Jones, John J. Obrycki, Arun Sethuraman, David W. Weisrock

Entomology Faculty Publications

Non-native lady beetle species have often been introduced, with variable success, into North America for bio- logical control of aphids, scales, whiteflies, and other agricultural pests. Two predatory lady beetle species, Propylea quatuordecimpunctata and Hippodamia variegata, both originating from Eurasia, were first discovered near Montreal, Quebec, in North America in 1968 and 1984, respectively, and have since expanded into northeastern North America and the midwestern United States. In this study, we estimate the range-wide pop- ulation structure, establishment and range-expansion, and recent evolutionary history of these lady beetle species using reduced-representation genotyping-by-sequencing via ddRADseq. In addition, we quantified the responses …

Staufenc Facilitates Utilization Of The Erad Pathway To Transport Dsrna Through The Endoplasmic Reticulum To The Cytosol, Jinmo Koo, Subba R. Palli

Entomology Faculty Publications

RNA interference (RNAi) is more efficient in coleopteran insects than other insects. StaufenC (StauC), a coleopteran-specific double-stranded RNA (dsRNA)-binding protein, is required for efficient RNAi in coleopterans. We investigated the function of StauC in the intracellular transport of dsRNA into the cytosol, where dsRNA is digested by Dicer enzymes and recruited by Argonauts to RNA-induced silencing complexes. Confocal microscopy and cellular organelle fractionation studies have shown that dsRNA is trafficked through the endoplasmic reticulum (ER) in coleopteran Colorado potato beetle (CPB) cells. StauC is localized to the ER in CPB cells, and StauC-knockdown caused the accumulation of dsRNA in the …

Effects Of The “High Impact Leadership For School Renewal” Project On Principal Leadership, School Leadership, And Student Achievement, Xin Ma, Jianping Shen, Patricia L. Reeves, Huang Wu, La Sonja Roberts, Yunzheng Zheng, Qianqian Chen

Educational, School, and Counseling Psychology Faculty Publications

In this study, we designed an educational experiment to evaluate the High Impact Leadership for School Renewal project’s impact on principal leadership, school leadership, and student achievement. Principals in the experimental group reported statistically significantly greater improvement in principal leadership than their counterparts in the control group (Hedge’s g of 0.73), but teachers in the experimental and control groups showed no difference in their ratings of principal leadership. Teachers in the experimental group reported statistically significantly more improvement in school leadership than their counterparts in the control group (Hedge’s g of 0.53 on the scale of Orientation to School Renewal …

Single-Cell Analysis Identifies Plk1 As A Driver Of Immunosuppressive Tumor Microenvironment In Luad, Yifan Kong, Chaohao Li, Jinpeng Liu, Sai Wu

Markey Cancer Center Faculty Publications

PLK1 (Polo-like kinase 1) plays a critical role in the progression of lung adenocarcinoma (LUAD). Recent studies have unveiled that targeting PLK1 improves the efficacy of immuno- therapy, highlighting its important role in the regulation of tumor immunity. Nevertheless, our understanding of the intricate interplay between PLK1 and the tumor microenvironment (TME) remains incomplete. Here, using genetically engineered mouse model and single- cell RNA-seq analysis, we report that PLK1 promotes an immunosuppressive TME in LUAD, characterized with enhanced M2 polarization of tumor associated macrophages (TAM) and dampened antigen presentation process. Mechanistically, elevated PLK1 coin- cides with increased secretion of CXCL2 …

Androgen Aggravates Aortic Aneurysms Via Suppression Of Pd-1 In Mice, Xufang Mu, Shu Liu, Zhuoran Wang, Kai Jiang, Timothy S. Mcclintock, Arnold Stromberg, Alejandro V. Tezanos, Eugene S. Lee, John A. Curci, Ming C. Gong, Zhenheng Guo

Markey Cancer Center Faculty Publications

Androgen has long been recognized for its pivotal role in the sexual dimorphism of cardiovascular diseases, including aortic aneurysms (AAs), a devastating vascular disease with a higher prevalence and fatality rate in men than in women. However, the mechanism by which androgen mediates AAs is largely unknown. Here, we found that male, not female, mice developed AAs when exposed to aldosterone and high salt (Aldo-salt). We revealed that androgen and androgen receptors (ARs) were crucial for this sexually dimorphic response to Aldo-salt. We identified programmed cell death protein 1 (PD-1), an immune checkpoint, as a key link between androgen and …

Smoking Cessation By Cancer Treatment Status Among Cervical Cancer Survivors, Cherell Cottrell-Daniels, Charles E. Hoogland, Bethany Shorey Fennell, Vani N. Simmons, Damon J. Vidrine, Jennifer I. Vidrine

Markey Cancer Center Faculty Publications

Introduction: Continued smoking following a cancer diagnosis is associated with poorer cancer treatment outcomes and survival times. Little is known about how cancer treatment status at the time of tobacco treatment enrollment impacts long-term smoking cessation outcomes. Using data from a smoking cessation RCT, this study compared long-term cessation outcomes of women undergoing active treatment for cervical cancer at trial enrollment (n=40) to outcomes of women with a history of cervical cancer or cervical intraepithelial neoplasia (CIN) who were not undergo- ing active cancer treatment at enrollment (n=154)

Methods: Participants (n=194) were randomized to Standard Treatment (ST) or ST plus …

Preference Of Dhurrin-Free Sorghum By Ewes, Shelby M. Gruss, Keith D. Johnson, John Scott Radcliffe, Ronald P. Lemenager, Mitchell R. Tuinstra

Animal and Food Sciences Faculty Publications

Sorghum [Sorghum bicolor (L.) Moench] is a resilient forage crop due to its drought tolerance and adaptation to low-N environments. Sorghum produces a cyanogenic glucoside called dhurrin. The breakdown of dhurrin leads to the release of hydrogen cyanide (HCN), which can cause cyanide toxicity in livestock. Dhurrin-free sorghum lines have been developed through chemical mutagenesis by mutagenizing the gene for the first enzyme, CYP79A1, in the biosynthetic pathway. The CYP79A1 mutation was bred into sorghum lines to create a dhurrin-free experimental hybrid. Grazing preference of ewes was assessed when allocated to the dhurrin-free hybrid and three commercial hybrids. Near isogenic …

Heart Failure In Nursing Homes: A Scoping Review Of Educational Interventions For Optimising Care Provision, James Mcmahon, David R. Thompson, Jan Cameron, Christine Brown Wilson, Loreena Hill, Paul Tierney, Doris Yu, Debra K. Moser, Karen Spilsbury, Nittaya Srisuk, Jos M. G. A. Schols, Mariëlle Van Der Velden, Gary Mitchell

UK CARES Faculty Publications

Background: Heart failure has an estimated global prevalence of 64.3 million cases, with an average age of a person living with heart failure at 75.2 years. Approximately 20% of residents living in nursing homes (a long-term residential care environment for some individuals) report living with heart failure. Residents living with heart failure in nursing home environments are often frail, have reduced quality of life, higher rates of rehospitalisation and mortality, and greater complications in heart failure management. Further, nursing home staff often lack the knowledge and skills required to provide the necessary care for those living with heart failure. Interventions …

Active And Retroactive Digital Newspaper Preservation, Andrew Mcdonnell

Library Presentations

This presentation was given at the 2024 International Federation of Library Associations and Institutions News Media Conference in Aarhus, Denmark on May 31, 2024. It illustrates a brief glimpse of the University of Kentucky's Digital Newspaper Preservation program, highlighting challenges presented by two new born-digital additions to the collection.

A Framework And Process For Community‑Engaged, Mixed‑Methods Cancer Needs Assessments, Todd Burus, Jessica R. Thompson, Caree R. Mcafee, Lovoria B. Williams, Jennifer R. Knight, Bin Huang, Sarojini Kanotra, Natalie P. Wilhite, Elaine Russell, Melinda Rogers, Connie L. Sorrell, Christine Stroebel, Rachael King, Pamela C. Hull

Markey Cancer Center Faculty Publications

Purpose

Community health needs assessments are required for most state and local public health agencies and non-profit hospitals. Typically based on community health improvement planning models, these assessments encompass overall com- munity health and multiple diseases to inform program planning. National Cancer Institute (NCI)-designated Cancer Centers and community-based cancer-focused programs share the goal of reducing cancer burden in the catchment areas they serve. However, to date, no published models exist to guide cancer-specific needs assessments for a determined geographic area that can inform both public health and research initiatives. The purpose of this article is to outline a cancer needs …

Social/Emotional Health, Mental Health And Quality Of Life Among Adults With Comorbid Diabetes And Hypertension: A Population-Based Cross-Sectional Study, Ranjita Misra, Sara Nayeem

Journal of Appalachian Health

Introduction: West Virginia has a disproportionately large population of rural adults with diabetes and hypertension, two common chronic, comorbid conditions that represent a national economic, social, and public health burden. Anxiety, depression, and severe mental illness are associated with poor motivation to engage in coping/self-care behaviors and related increased morbidity/mortality.

Purpose: This study examines the relationship between self-reported mental health, selected social and emotional health factors, health-related quality of life (HRQoL), and clinical outcomes among adults with comorbid diabetes and hypertension.

Methods: This cross-sectional study consisted of 75 participants who participated in a diabetes and hypertension self-management program (DHSMP) in …

Disasters And Impacts In Appalachian Kentucky: A Behavioral Health Analysis, Walter David Mathews Phd, Joseph M. Clark, Amy S. Potts

Journal of Appalachian Health

Introduction: Major disasters continue to occur in Appalachian Kentucky with devastating consequences. A major disaster, defined by the Federal Emergency Management Agency (FEMA) as an event too large for a community to manage without outside help, involves emergency responders from the local, state, and federal disaster agencies, plus national volunteers.

Purpose: This paper reports on recent disasters in eight southeast Kentucky counties, the changing nature of these disasters, and the behavioral health impact on the people affected.

Methods: In this large-scale disaster survey in the Appalachian counties in Southeast Kentucky, over 3,500 people were asked about their recent disaster experiences …

Community Needs Assessment Collaboration Following The July 2022 Flooding In Eastern Kentucky, Melissa Slone Dsw, Frances Feltner Dnp, William M. Baker Rn, Anthony S. Lockard Msw, Csw, Angela Raleigh Rd

Journal of Appalachian Health

Rapidly rising waters due to flash floods and thunderstorms on the night of July 27, 2022, resulted in hundreds of water rescues throughout 14 rural Appalachian Kentucky counties. Lives were lost, thousands were injured, homes and property were damaged or destroyed, and many roadways were unpassable. Community partners serving these counties collaborated to design and conduct an assessment to gain a better understanding of the needs of individuals residing in certain remote sections within the communities. The assessment, conducted three months after the flood, collected information regarding flooding impact on housing, physical and behavioral health, transportation, work, and finances.

Clinical And Genomic Features Of Patients With Renal Cell Carcinoma And Advanced Chronic Kidney Disease: Analysis Of A Multi-Institutional Database., Corbin J. Eule, Junxiao Hu, Dale Hedges, Alkesh Jani, Thomas Pshak, Brandon J. Manley, Alejandro Sanchez, Robert Dreicer, Zin W. Myint, Yousef Zakharia, Elaine T. Lam

Markey Cancer Center Faculty Publications

BACKGROUND: Patients with advanced chronic kidney disease (ACKD) are at an increased risk of developing renal cell carcinoma (RCC), but molecular alterations in RCC specimens arising from ACKD and overall survival (OS) in affected patients are not well defined.

PATIENTS AND METHODS: Using the Oncology Research Information Exchange Network (ORIEN) Total Cancer Care

RESULTS: Of 296 patients with RCC, 61 met the criteria for ACKD. The most common somatic mutations in the overall cohort were in

CONCLUSIONS: Using the clinicogenomic ORIEN database, our study found lower rates of

Travel-Time Disparities In Access To Proton Beam Therapy For Cancer Treatment, Todd Burus, Alexander D. Vanhelene, Michael K. Rooney, Krystle A. Lang Kuhs, W. Jay Christian, Christopher Mcnair, Sanjay Mishra, Arnold C. Paulino, Grace L. Smith, Steven J. Frank, Jeremy L. Warner

Markey Cancer Center Faculty Publications

IMPORTANCE Proton beam therapy is an emerging radiotherapy treatment for patients with cancer that may produce similar outcomes as traditional photon-based therapy for many cancers while delivering lower amounts of toxic radiation to surrounding tissue. Geographic proximity to a proton facility is a critical component of ensuring equitable access both for indicated diagnoses and ongoing clinical trials.

OBJECTIVE To characterize the distribution of proton facilities in the US, quantify drive-time access for the population, and investigate the likelihood of long commutes for certain population subgroups.

DESIGN, SETTING, AND PARTICIPANTS This population-based cross-sectional study analyzed travel times to proton facilities in …

Epri Research On Innovative Techniques For Alternative Source Demonstrations, Bruce Hensel, Charles Cravotta Iii, Michael Pribil, Christopher Bagwell

World of Coal Ash Proceedings

EPRI Research on Innovative Techniques for Alternative Source Demonstrations Authors Mr. Bruce Hensel - United States - Electric Power Research Institute Dr. Charles Cravotta III - United States - United States Geological Survey Mr. Michael Pribil - United States - United States Geological Survey Dr. Christopher Bagwell - United States - Pacific Northwest National Laboratory Mr. R. Jeffrey Davis - United States - INTEGRAL CONSULTING INC. Mr. Jared Carte - United States - United States Geological Survey Mr. Danny Rutherford - United States - United States Geological Survey Dr. Frederick Day-Lewis - United States - Pacific Northwest National Laboratory Ms. …

Paper_Strategic Workforce Solutions In The Coal Ash Industry- Navigating Talent Challenges For Consultants, Civil Companies, And Utilities, Stuart Keeter

World of Coal Ash Proceedings

"Strategic Workforce Solutions in the Coal Ash Industry: Navigating Talent Challenges for Consultants, Civil Companies, and Utilities" Authors Mr. Stuart Keeter - United States - MRI Raleigh Abstract The pervasive shortage of technical and engineering workers has emerged as a pressing concern for companies grappling with extensive infrastructure projects in the United States. In the September/October 2022 issue of Civil Engineering, ASCE’s 2022 president, Dennis Truax, highlights the urgency, noting the need for approximately 25,000 new civil engineers annually according to the US Bureau of Labor Statistics. As an experienced recruiter specializing in heavy civil, consulting, and utility sectors, I …