Digital Commons Network^™

Editorial: Roles Of Sleep Disruption And Circadian Rhythm Alterations On Neurodegeneration And Alzheimer's Disease, Marilyn J. Duncan, Sigrid C. Veasey, Phyllis Zee

Neuroscience Faculty Publications

No abstract provided.

Apoε4 Lowers Energy Expenditure In Females And Impairs Glucose Oxidation By Increasing Flux Through Aerobic Glycolysis, Brandon C. Farmer, Holden C. Williams, Nicholas A. Devanney, Margaret A. Piron, Grant K. Nation, David J. Carter, Adeline E. Walsh, Rebika Khanal, Lyndsay E. A. Young, Jude C. Kluemper, Gabriela Hernandez, Elizabeth J. Allenger, Rachel Mooney, Lesley R. Golden, Cathryn T. Smith, J. Anthony Brandon, Vedant A. Gupta, Philip A. Kern, Matthew S. Gentry, Josh M. Morganti, Ramon C. Sun, Lance A. Johnson

Physiology Faculty Publications

BACKGROUND: Cerebral glucose hypometabolism is consistently observed in individuals with Alzheimer's disease (AD), as well as in young cognitively normal carriers of the Ε4 allele of Apolipoprotein E (APOE), the strongest genetic predictor of late-onset AD. While this clinical feature has been described for over two decades, the mechanism underlying these changes in cerebral glucose metabolism remains a critical knowledge gap in the field.

METHODS: Here, we undertook a multi-omic approach by combining single-cell RNA sequencing (scRNAseq) and stable isotope resolved metabolomics (SIRM) to define a metabolic rewiring across astrocytes, brain tissue, mice, and human subjects expressing APOE4.

RESULTS: Single-cell …

Bone Quality And Fractures In Women With Osteoporosis Treated With Bisphosphonates For 1 To 14 Years, Hartmut H. Malluche, Jin Chen, Florence Lima, Lucas J. Liu, Marie-Claude Monier-Faugere, David A. Pienkowski

Internal Medicine Faculty Publications

Oral bisphosphonates are the primary medication for osteoporosis, but concerns exist regarding potential bone-quality changes or low-energy fractures. This cross-sectional study used artificial intelligence methods to analyze relationships among bisphosphonate treatment duration, a wide variety of bone-quality parameters, and low-energy fractures. Fourier transform infrared spectroscopy and histomorphometry quantified bone-quality parameters in 67 osteoporotic women treated with oral bisphosphonates for 1 to 14 years. Artificial intelligence methods established two models relating bisphosphonate treatment duration to bone-quality changes and to low-energy clinical fractures. The model relating bisphosphonate treatment duration to bone quality demonstrated optimal performance when treatment durations of 1 to 8 …

Genetic Diversity In The Anthracnose Pathogen Infecting Stylosanthes In Brazil, India And China, P. Weeds, S. Chakraborty, Celso D. Fernandes, M. J. Charchar, C. R. Ramesh, Guodao Liu, S. Kelemu

IGC Proceedings (1977-2023)

This work aimed to determine the genetic diversity of Colletotrichum gloeosporioides infecting Stylosanthes spp. in Brazil, China and India. A total of 132 isolate originating from S. seabrana, S. macrocephala, S. capitata, S. scabra, and S. guianensis were used. Four major genetic groups were identified from an analysis of genetic diversity using selection-neutral DNA markers. Group 1 contained 20 isolates and this may represent a genotype that migrated from the center of diversity in Brazil and Colombia to Australia, Thailand and India. Group 2 consisted of 66 Brazilian isolates and group 3 had 19 isolates from …

Relationship Between Tree Density And Grass Dry Matter Yield In A Southern African Savanna, G. N. Smit

IGC Proceedings (1977-2023)

The investigation was carried out on a densely wooded area in the Mopani savanna of South Africa. Seven plots were subjected to different intensities of tree thinning, ranging from a totally cleared plot (0 %) to plots thinned to the equivalent of 10 %, 20 %, 35 %, 50 % and 75 % of the leaf biomass of a control plot (100 %). The grasses responded positively to the tree thinning in terms of total dry matter yield. The yields between tree canopies were generally of the same order or higher than under tree canopies, with the yields where trees …

Seasonal Patterns Of Growth And Senescence In Cynodon Spp. Cv Tifton 85 Grazed Swards, L. F. M. Pinto, L. G. Barioni, S. C. Da Silva

IGC Proceedings (1977-2023)

Growth and senescence are very important determinants of grassland productivity and correspond to key features to be considered for grazing management purposes. The present study was carried out at ESALQ, Piracicaba, S.P., Brazil and evaluated growth and senescence as a function of sward surface height. Mathematical models generated revealed that a similar pattern of response occurred as described in the literature for temperate grass species. However, a seasonal variation in response curves for growth and senescence was also observed and could be related to climatic events. Highest herbage accumulation rates were observed within the range of 15 to 20 cm …

Yields And Sward Characteristics Of Timothy Cultivars Under Grazing, H. T. Kunelius, G. H. Dürr, K. B. Mcrae, S. A. E. Fillmore

IGC Proceedings (1977-2023)

Seven timothy (Phleum pratense L.) cultivars were evaluated over three pasture seasons under rotational grazing to 7 or 11 cm post-grazing heights and regrowth periods of four to seven weeks. There was a trend for the pasture type timothy cultivars to outyield Champ timothy (check). Dry matter yields were lower for the 7 cm than 11 cm post-grazing height. Although the overall cultivar x post-grazing height interaction was not significant (P > 0.05), there was variability in grazing tolerance among timothy cultivars. Yield of Kahu was maintained and vegetative tiller density of Kahu increased over the experimental period under 7 …

A Technique For Assessing Seed Survival Of New Pasture Legumes Following Grazing By Sheep, Caroline T. De Koning, P. E. Beale, A. J. Duncan, S. Hughes, K. Haskard

IGC Proceedings (1977-2023)

A technique for assessing the fate of seed grazed by sheep in small field plots was examined using the pasture species Trifolium michelianum cv. Paradana, Medicago truncatula cv. Mogul, Trifolium spumosum and Trigonella balansae. Trifolium spumosum lost the greatest proportion of seed from dry pasture residues (88% seed eaten), whereas Trigonella balansae, Paradana and Mogul lost 61%, 55% and 53% respectively. However, Trifolium spumosum and Paradana had high levels of seed in the faeces (56.8 kg/ha and 65.2 kg/ha respectively), whereas Mogul and Trigonella balansae had low levels (10.3 kg/ha and 11.0 kg/ha respectively). Mogul, due to it's …

Seasonal Growth Curves Of Perennial Ryegrass In Mexico, M. E. Z. Velasco, Alfonso Hernández-Garay, J. P. Pérez, V. A. González-Hernández

IGC Proceedings (1977-2023)

An experiment was established at Colegio de Postgraduados Research Station, Texcoco, México to evaluate the seasonal pattern of growth curve of perennial ryegrass (Lolium perenne) swards. Growth rate increases rapidly from a low level immediately after defoliation, and eventually reaches an equilibrium level as the amount of green leaf in the sward stabilize. The time required to reach this state varied according to the season of year, with the four seasons ranked in the order: spring (4 weeks) < summer (5 weeks) < autumn and winter (6 weeks). Once swards reached equilibrium, growth rates started to decline as a consequence of an increase in dead material and pseudostem. These increases were highest in spring and lowest in winter. The results of this study suggest that sward management to maximise herbage production and utilisation in ryegrass swards must be done once the highest green leaf mass is reached. In this trial, it was reached at 5, 6, 6 and 4 weeks in summer, autumn, winter and spring, respectively.

The Effects Of Planting Density On The Dry Matter Yield And The Overwintering Ability Of The Dwarf And Normal Napiergrasses In Two Years After Planting, Yasuyuki Ishii, M. M. Mukhtar, Sayan Tudsri

IGC Proceedings (1977-2023)

The objective of this study is to determine the optimum planting density in napiergrass (Pennisetum purpureum Schumach) among two dwarf varieties introduced from Thailand and two normal ones under three levels of density. Dwarf varieties showed lower plant height and mean tiller weight, and higher leaf area index (LAI) and leaf blade percentage. Crop growth rate was positively correlated with LAI, and net assimilation rate and canopy extinction coefficient (K) were negatively correlated with LAI in the second year, including all dwarf and normal varieties, while K tended to be lower in the dwarf varieties. With the increase in …

Light Interception And Dry Matter Yield In Grass/Legume Mixtures, H. A. Jönsson

IGC Proceedings (1977-2023)

The influence of grass variety on light interception and dry matter yield in a grass/clover mixture was studied. Two varieties of timothy (Phleum pratense L.) and five varieties of ryegrass (Lolium spp) as components in a mixture were compared during the spring period up to the first cut of the third harvest year. By replacing the timothy variety in the mixture both light interception and dry matter yield were significantly affected. The leaf orientation was thought to be a contributing factor with erect leaves intercepting less light. There were no significant differences neither in light interception nor …

Photosynthetic Light Response Of Tanzania Grass Under Four Levels Of Leaf Temperature, A. C. L. De Mello, P. M. Santos, Carlos G. S. Pedreira, M. Corsi, C. T. Dos S. Dias

IGC Proceedings (1977-2023)

The purpose of this paper is to establish photosynthetic light response curves for Tanzania grass (Panicum maximum Jacq.) under four leaf temperature levels. Photosynthetic rate was measured as a response to levels of photosynthetic photon flux density (PPFD) on the youngest fully expanded leaves of 12 representative tillers with an infra red gas analyzer. The effect of PPFD was tested for each leaf temperature level in a randomized complete block design. Photosynthetic light response curves were adjusted for each leaf temperature using a non-linear hyperbolic model. The maximum photosynthetic response was 25,59; 31,43; 34,57 and 27,53 µmol CO_{2 …}

Nonstructural Carbohydrate Reserves Of Temperate Perennial Grasses In Autumn Early Growth, Y. Tamura, K. Matoba, A. Fushimi, M. Moriyama

IGC Proceedings (1977-2023)

The objective of this study was to determine levels of nonstructural carbohydrate reserves of four temperate perennial grasses: Orchardgrass (Dactylis glomerata L.), Timothy (Phleum pratense L.), Perennial ryegrass (Lolium perenne L.), and Reed canarygrass (Phalaris arundinacea L.) in their early growth stages during the cool autumn temperatures in northern Japan. At the time of sampling, all grasses were in their vegetative stage, and Reed canarygrass was not forming rhizomes. Fructosan concentration in reed canarygrass roots (8.04%) was 22 times that of the leaf blade (0.36%) and twice that of the stem (3.40%); the concentration in reed …

Fusion And Beyond: Satellite Cell Contributions To Loading-Induced Skeletal Muscle Adaptation, Kevin A. Murach, Christopher S. Fry, Esther E. Dupont-Versteegden, John J. Mccarthy, Charlotte A. Peterson

Center for Muscle Biology Faculty Publications

Satellite cells support adult skeletal muscle fiber adaptations to loading in numerous ways. The fusion of satellite cells, driven by cell-autonomous and/or extrinsic factors, contributes new myonuclei to muscle fibers, associates with load-induced hypertrophy, and may support focal membrane damage repair and long-term myonuclear transcriptional output. Recent studies have also revealed that satellite cells communicate within their niche to mediate muscle remodeling in response to resistance exercise, regulating the activity of numerous cell types through various mechanisms such as secretory signaling and cell–cell contact. Muscular adaptation to resistance and endurance activity can be initiated and sustained for a period of …

Competitive Rationales: Beneath The Surface Of Competitive Behavior, Goce Andrevski, Danny Miller, Isabelle Le Breton-Miller, Walter Ferrier

Management Faculty Publications

Competitive dynamics research has focused on studying whether rivals are able and likely to carry out competitive actions, typically by examining indirect reasons such as characteristics of the actions themselves, the firms involved, or the competitive context. We explore why rivals initiate a specific competitive action at a particular time and situation. Drawing from the philosophy of action literature, we introduce the concept of competitive rationales to examine the primary reasons that cause tactical actions. Given the rapid exchanges characterizing tactical competitive dynamics, we conducted an inductive, multicase study to explore the reasons behind over 800 discrete tactical decisions carried …

Effect Of Cutting Height On Tiller Population Density And Herbage Biomass Of Buffel Grass, L. S. Beltrán, P. J. Pérez, G. A. Hernández, M. E. García, S. J. Kohashi, H. J. G. Herrera

IGC Proceedings (1977-2023)

The aim of this trial was to investigate the effect of different cutting heights on tiller population density and herbage biomass of Buffel grass (Cenchrus ciliaris L) grown in miniature swards in a greenhouse. Four treatments with five replicates: five cm, ten cm, and 20 cm cutting height, and control (without cut) were randomly allocated. Intensity of defoliation affected the cumulative herbage harvested; the ten cm cutting height was greater (404.1 g DM m^-2) than 5 cm (317.6 g DM m^-2) and 20 cm (263.9 g DM m^-2), respectively. Cumulative herbage harvested in …

Leaf Appearance Rate In Brachiaria Decumbens Grown In Nitrogen And Potassium Rates, M. D. C. Ferragine, F. A. Monteiro, S. C. Da Silva

IGC Proceedings (1977-2023)

A greenhouse experiment was carried out with Brachiaria decumbens Stapf. cv. Basilisk grown in nutrient solution. Five nitrogen rates (42; 140; 238; 336 and 434 mg/L) and three potassium rates (78; 234 and 390 mg/L) were studied in a factorial experiment, in a randomized complete block design, with four replications. Green leaf number was evaluated in six times in the first period of growth (27, 30, 33, 36, 39 and 42 days after transplanting) and nine times in the second period (45, 48, 51, 54, 57, 60, 63, 66 and 69 days after transplanting). Data was registered in three plants …

Morphogenesis And Defoliation Frequency Of Italian Ryegrass (Lolium Multiflorum) And Paspalum Urvillei In Lowland Under Three Levels Of P And K, Fernando L. F. De Quadros, A. G. S. Pigatto, D. G. Bandinelli, E. Marchezan, Marta G. Da Rocha

IGC Proceedings (1977-2023)

This trial was conducted to evaluate growth dynamics and defoliation frequency of Italian ryegrass (Lolium multiflorum) and Paspalum urvillei in a lowland area under three levels of P and K. Using randomization tests we observed that, in a general way, fertilizer treatments were not the determinant factors of leaf appearance and elongation rates for both species. Only the leaf appearance rate of Paspalum urvillei at 100 % of recommendation level and the elongation rate for Italian ryegrass, in the same treatment, was different. Probably other factors, like drainage, are contributing to these results. I. ryegrass phyllochron ranged from …

Variability In Herbage Mass And Chemical Composition Within A Timothy Sward, O. Niemeläinen, E. Miettinen, P. Virkajärvi, L. Alakukku, K. Hakala

IGC Proceedings (1977-2023)

Variability in herbage mass (HM) and chemical composition of timothy (Phleum pratense L.) sward was studied in a three-hectare field. The field, which was flat, was divided into twelve sections and a sampling site was randomly selected in each. The study was carried out in Sotkamo (64^o 01’N, 28^o22’E) research station in Finland. Snow depth and frost conditions were measured in winter and soil water content was monitored in the growing season at each sampling site. Observations on the crop included assessment of herbage ground cover and winter damage percentage, stand height and HM and analysis …

Effects Of Temperature, Nitrogen Fertilisation And Leaf And Tiller Age On Specific Leaf Area Of Brachiaria Decumbens, J. Busqué, M. Herrero

IGC Proceedings (1977-2023)

Signal grass (Brachiaria decumbens Stapf) micro-swards were grown under controlled environmental conditions at different temperatures and nitrogen fertilisation rates. Specific leaf area was responsive both to temperature and nitrogen, but did not change with the level of insertion of the leaf in the tiller. Senescing leaves had higher specific leaf area than old extended green leaves and these had higher values than new extended green leaves. Changes in specific leaf area were more related to changes in leaf area and more exactly to changes in leaf width.

Influence Of Speed, Ground Surface And Shoeing Condition On Hoof Breakover Duration In Galloping Thoroughbred Racehorses, Kate Horan, James Coburn, Kieran Kourdache, Peter Day, Dan Harborne, Liam Brinkley, Henry Carnall, Lucy Hammond, Michael L. Peterson, Sean Millard, Thilo Pfau

Biosystems and Agricultural Engineering Faculty Publications

Understanding the effect of horseshoe–surface combinations on hoof kinematics at gallop is relevant for optimising performance and minimising injury in racehorse–jockey dyads. This intervention study assessed hoof breakover duration in Thoroughbred ex-racehorses from the British Racing School galloping on turf and artificial tracks in four shoeing conditions: aluminium, barefoot, aluminium–rubber composite (GluShu) and steel. Shoe–surface combinations were tested in a randomized order and horse–jockey pairings (n = 14) remained constant. High-speed video cameras (Sony DSC-RX100M5) filmed the hoof-ground interactions at 1000 frames per second. The time taken for a hoof marker wand fixed to the lateral hoof wall to …

Knowledge And Beliefs Associated With Environmental Health Literacy: A Case Study Focused On Toxic Metals Contamination Of Well Water, Kathleen M. Gray, Victoria Triana, Marti Lindsey, Benjamin Richmond, Anna G. Hoover, Chris Wiesen

Preventive Medicine and Environmental Health Faculty Publications

Environmental health literacy (EHL) is developing as a framework that can inform educational interventions designed to facilitate individual and collective action to protect health, yet EHL measurement poses several challenges. While some studies have measured environmental health knowledge resulting from interventions, few have incorporated skills and self-efficacy. In this study, a process-focused EHL instrument was developed, using the Newest Vital Sign (NVS) health literacy instrument as a model and tailoring it for the context of private well contamination with toxic metals. Forty-seven (47) participants, including undergraduate students and residents of communities with contaminated well water, piloted a prototype EHL instrument …

Using Technology To Enhance Teaching And Learning In Pharmacy Education, Clark D. Kebodeaux, Vivienne Mak

Pharmacy Practice and Science Faculty Publications

No abstract provided.

The Use Of Cover Crops After A Maize Crop In The North Of Spain, D. Báez, M. Pinto, M. Rodríguez, G. Besga, J. M. Estavillo

IGC Proceedings (1977-2023)

This work intends to study N leaching losses in a field assay when crimson clover (Trifolium incarnatum) and italian ryegrass (Lolium multiflorum) was incorporated into the soil and quantify the their effect on N₂O, N total gaseous losses under controlled soil moisture and temperature conditions. Field assay: A split-plot design where main plot was the cover crop and the subplot was the rate of fertilizer (0 and 150 kg N ha^-1) applied to the subsequent maize crop. Laboratory assay: Residues of italian ryegrass and crimson clover were mixed with soil in containers, …

Multi-Year Application Of Dairy Slurry On Grassland: Effects On Crop, Soil Biota, Soil Nutrients, And N2O Emission, Shabtai Bittman, C. G. Kowalenko, D. E. Hunt, N. Patni, J. Paul, D. Raworth, J. Hountin, T. A. Forge, C. M. Monreal, O. Schmidt

IGC Proceedings (1977-2023)

The long-term effects of using manure as the principal nutrient source in intensive crop production systems are not well known. This paper reports on the effects of multi-year application of fertilizer or dairy slurry on a tall fescue (Festuca arundinacea Schreb.) sward. Slurry sustained greater grass yield than chemical fertilizer. Unlike fertilizer, slurry supplied 70 to 120 kg N/ha one year after application but little after one year; 4-years of manure applications built up the stable organic matter pool in the soil. Manure-N was less prone to leaching but more prone to N₂O emissions than fertilizer-N. Manured …

Sewage Sludge As An Alternative Fertilizer For Tropical Pasture Grasses, M. B. Adjei, J. E. Rechcigl

IGC Proceedings (1977-2023)

This study was conducted to determine the effects of source (Liquid sludge at pH 7 (LS7) or pH 11 (LS11), cake biosolid (CB) or ammonium nitrate (AM)) by rate (0, 80 or 160 kg ha^-1) of N application on bahiagrass forage yield, quality and tissue composition. Same plots were fertilized in March 1998 and 1999. Forage yield was measured at 30 d intervals from May through November and subsamples were dried and ground for quality analyses. The 2-year mean forage yield was similar for AM, LS7 and LS 11 fertilizer applications. Forage yield from CB application was 30% …

Letter To Editor Regarding The Ocean Study, Barbara P. Yawn, Barry Make, David M. Mannino, Fernando J. Martinez, Meilan K. Han

Preventive Medicine and Environmental Health Faculty Publications

No abstract provided.

Engineering Properties Of Sweet Potato Starch For Industrial Applications By Biotechnological Techniques Including Genome Editing, Ruiqing Lyu, Sulaiman Ahmed, Weijuan Fan, Jun Yang, Xiaoyun Wu, Wenzhi Zhou, Peng Zhang, Ling Yuan, Hongxia Wang

Plant and Soil Sciences Faculty Publications

Sweet potato (Ipomoea batatas) is one of the largest food crops in the world. Due to its abundance of starch, sweet potato is a valuable ingredient in food derivatives, dietary supplements, and industrial raw materials. In addition, due to its ability to adapt to a wide range of harsh climate and soil conditions, sweet potato is a crop that copes well with the environmental stresses caused by climate change. However, due to the complexity of the sweet potato genome and the long breeding cycle, our ability to modify sweet potato starch is limited. In this review, we cover …

Phosphorus Fertilizer And Stocking Rate Effects On Soil Microbial Biomass Of A Long-Term Dairy Farmlet Experiment, S. R. Aarons, C. R. O’Connor, C. J. P. Gourley

IGC Proceedings (1977-2023)

The effects of a range of P fertilizer rates and dairy cow stocking rates on microbial biomass carbon and phosphorus were compared in a long-term farmlet trial in southeastern Australia. Pastures were stocked at 2, 3, or 4 cows/ha and received fertilizer at rates of 0, 35, 70 or 140 kgP/ha. There was no effect of either P fertilizer rate or stocking rate on microbial biomass C from 1995 to 1998. Increasing P application rate significantly increased the chloroform-released microbial P flush measured, but stocking rate had no effect on microbial P. There were significant temporal changes, with the seasonal …

Dry Matter Accumulation And Partitioning Between Vegetative And Reproductive Organs In Alfalfa (Medicago Sativa L.), E. D. Bolaños-Aguilar, Christian Huyghe, B. Julier, C. Ecalle

IGC Proceedings (1977-2023)

This work investigated the partitioning of dry matter between vegetative and reproductive plant organs in alfalfa during the reproductive period under field conditions. Two French varieties (Europe and Magali) were studied. Both varieties showed similar growth pattern of the different plant organs in 1998 and 1999. The mean dry matter of vegetative organs (shoots and leaves) over the two years was higher in Europe (567g/m²) than Magali (470g/m²). No vegetative growth was observed during the reproductive period. The root organs (measured to a depth of 0.20 m) and the reproductive organs showed an increase in dry …