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A Geopolitical Economy Analysis Of China And India’S Approaches To Transnational Data Governance, Yujia He, Ka Zeng Jan 2025

A Geopolitical Economy Analysis Of China And India’S Approaches To Transnational Data Governance, Yujia He, Ka Zeng

Patterson School of Diplomacy and International Commerce Faculty Publications

Recent literature on the behavior of rising powers in digital trade and data governance highlights their discourses of data sovereignty and desire to preserve domestic policy autonomy. This article contributes to the literature by employing a political economy lens that shifts the focus from the nation-state/inter-state framework towards the dynamics of state–capital relations, allowing for a more historical and contextual understanding of the geopolitics of data governance in emerging economies. Using China and India—two of the largest emerging economies—as comparative cases, and drawing on secondary data from government documents and other sources, the article argues that the interplay between the …


“Single Girl, Married Girl:” Female Perspectives On Marriage, Maidenhood, And Motherhood In English-Language Folk Music, Avery Schanbacher Jan 2025

“Single Girl, Married Girl:” Female Perspectives On Marriage, Maidenhood, And Motherhood In English-Language Folk Music, Avery Schanbacher

Libraries Award for Undergraduate Scholarship

In 1928, the Carter Family released “Single Girl, Married Girl.” The recording featured only Sara and Maybelle Carter, and in three short stanzas, highlighted the vastly differing lives of the single girl, who dressed fine and went where she pleased, and the married girl, with a baby on her knee, who rocked the cradle and cried. Sara and Maybelle Carter weren’t the only people who knew this song – before they recorded it for Ralph Peer at the famous Bristol sessions, it was alive as a part of musical traditions not just in their home in Scott County, Virginia, but …


Ioto: Never Open A Stiff Lid Again, Gabriel Portugal Jan 2025

Ioto: Never Open A Stiff Lid Again, Gabriel Portugal

Libraries Award for Undergraduate Scholarship

Background: From baby food to pickles, food jars are a common find in American homes. Unfortunately,  the task of opening a stiff jar lid can be very difficult for consumers with lower grip strength, parkinsons,  or arthritis. While there are a variety of products on the market to help make this easier, there exist few jar  openers that can be used by these consumers. Objective: This project aimed to research and develop  (R&D) an improved hands-free jar opener that is accessible for consumers with the most advanced  cases of limited arm strength. Methods: R&D followed a Design Thinking approach with …


Body Mass Index, Sleep, And Food Insecurity Predict Prevalence Of Anxiety And Depression In College Students, Makenzie Barr-Porter, Amelia Sullivan, Jade Mcnamara Jan 2025

Body Mass Index, Sleep, And Food Insecurity Predict Prevalence Of Anxiety And Depression In College Students, Makenzie Barr-Porter, Amelia Sullivan, Jade Mcnamara

Dietetics and Human Nutrition Faculty Publications

This study aimed to assess the relationship between mental health, health behaviors, and food security in young adults in a university environment. Young adults (N = 536) at two United States universities completed a survey assessing health behaviors and characteristics. Logistic regression determined the odds of anxiety and/or depression based on gender identity, body mass index (BMI), food security status (FSS), and sleep restfulness. Over one-third of students were food insecure (36.7%), and almost all reported anxiety (57%) and/or depression (39.1%). Students who identified as female, reported very low FSS, poor sleep, and had higher BMI were at greater odds …


Current Practices In Training Paraeducators: A Literature Review, Rebekah Pearson Jan 2025

Current Practices In Training Paraeducators: A Literature Review, Rebekah Pearson

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

I conducted a brief literature review to examine current practices for training paraeducators in school settings. I reviewed literature published after 2010 using an online database. Using an author-made inclusion criterion, 13 articles were considered for review. Findings suggest that behavior skills training (BST), brief performance feedback, didactic training, and a strategy instruction framework are currently being used to train paraeducators. These trainings have yielded positive results in increasing desired paraeducator behaviors. I conclude by discussing the limitations and directions for future research.


Comparison Of Video Modeling And Naturalistic Time Delay For Children With Autism In Preschool Classrooms, Makenna A. Briggs Jan 2025

Comparison Of Video Modeling And Naturalistic Time Delay For Children With Autism In Preschool Classrooms, Makenna A. Briggs

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

This study presents findings from an alternating adapted treatments design (AATD) that compared the use of video modeling and naturalistic time delay to teach language targets to children with autism. The research included two U.S. preschool students with a provisional diagnosis of autism spectrum disorder (ASD). Both participants met criterion with time delay.


Influence Of Naturalistic Language Intervention On Child Communication And Engagement, Olivia R. Abate Jan 2025

Influence Of Naturalistic Language Intervention On Child Communication And Engagement, Olivia R. Abate

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The purpose of this study is to parallel naturalistic instructional contexts that often occur during caregiver-child interactions (e.g., one-to-one arrangement during play) to learn more about how children respond when prompting is introduced compared to responsive interaction strategies alone or with environmental arrangement strategies. This exploratory study was designed to evaluate the potential differential effects within an ATD, comparing RI alone, RI + EA, and RI + MP on joint engagement, communication acts, and interfering behaviors. This study is ongoing and lacks results for communication acts. Preliminary results supported and contradicted aspects of the hypothesis: joint engagement would occur at …


Enhancing Communication For Individuals With Complex Communication Needs: The Critical Role Of Training And Evidence-Based Aac Strategies, Rachel H. Williams Jan 2025

Enhancing Communication For Individuals With Complex Communication Needs: The Critical Role Of Training And Evidence-Based Aac Strategies, Rachel H. Williams

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Professional training and evidence-based strategies can enhance communication for individuals with complex communication needs (CCN). These individuals often require augmentative and alternative communication (AAC) systems to express themselves effectively. However, the success of AAC use depends largely on the competence of educators, speech-language pathologists, and other support personnel. The paper emphasizes the necessity of targeted professional development in strategies such as aided language modeling (ALM) and core vocabulary instruction. ALM involves modeling AAC use in natural contexts, while core vocabulary instruction focuses on teaching high- frequency, versatile words to support generative and functional communication. Integrating these strategies across settings improves …


Assessing Generalization Along Side Acquisition Using System Of Least Prompts Versus Video Modeling Plus System Of Least Prompts Of Simulated Vocational Tasks, Victoria B. Shafer Jan 2025

Assessing Generalization Along Side Acquisition Using System Of Least Prompts Versus Video Modeling Plus System Of Least Prompts Of Simulated Vocational Tasks, Victoria B. Shafer

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The purpose of this study was to assess if system of least prompts alone or video modeling plus system of least prompts was more effective when teaching a student with a moderate intellectual disability three simulated vocational tasks using paper materials. Additionally, generalization was assessed using real-world materials. An adapted alternating treatment design was used to compare conditions. The results indicated that system of least prompts alone was more effective than video modeling plus system of least prompts. There was no demonstration of generalization.


Effectiveness Of Class-Wide Function Related Intervention Teams On The On-Task Behavior Of Middle School Students With Disabilities In A Resource Settings, Sharon Manikya Jan 2025

Effectiveness Of Class-Wide Function Related Intervention Teams On The On-Task Behavior Of Middle School Students With Disabilities In A Resource Settings, Sharon Manikya

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The current study examined the effectiveness of Class-Wide Function-related Intervention Teams (CW-FIT) in promoting on-task behavior and improving classroom functioning. The study was conducted with five students, and a single-subject withdrawal experimental design was used to evaluate the impact of CW-FIT on students’ behavior. Results demonstrated a functional relation between the intervention and increased on-task behavior. Overall, findings indicated that CW-FIT had a positive effect on student behavior and classroom functioning, suggesting that the intervention is an effective strategy for enhancing engagement and promoting a productive learning environment. Implications for future research include examining CW-FIT with larger groups of students, …


Evaluating A Naturalistic Language Intervention With Students With Complex Communication Needs In An Elementary Classroom, Kristina M. Johnson Jan 2025

Evaluating A Naturalistic Language Intervention With Students With Complex Communication Needs In An Elementary Classroom, Kristina M. Johnson

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Communication is an essential skill for all students, but specifically for students with moderate to severe disabilities. Through communication, our students with disabilities express their wants and need, make and maintain relationships, and participate in daily activities at home, school, and in the community. Play is a natural and motivating activity that encourages communication in all settings. Thus, I looked at using naturalistic language intervention (NLI) as an intervention strategy to increase expressive communication skills in my students with expressive language deficits. This project aimed to increase expressive communication skills in three elementary students with moderate to severe disabilities by …


A Program Evaluation Case Study, Madelyne G. Culbertson Jan 2025

A Program Evaluation Case Study, Madelyne G. Culbertson

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

This case study presents a program evaluation of a physical activity intervention implemented in Bourbon County, Kentucky, guided by the Centers for Disease Control and Prevention’s Framework for Program Evaluation in Public Health.


Increasing Hpv Vaccination Adherence In Floyd County, Ky: Give Teens Vaccines, Taylor M. Stumbo Jan 2025

Increasing Hpv Vaccination Adherence In Floyd County, Ky: Give Teens Vaccines, Taylor M. Stumbo

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Cervical cancer remains a pressing public health issue, particularly in underserved and rural areas where access to preventive care is limited. This capstone addresses the urgent need to increase human papillomavirus (HPV) vaccination adherence in Floyd County, Kentucky—part of the central Appalachian region that experiences disproportionately high cervical cancer incidence and mortality. Despite the proven effectiveness of HPV vaccines in preventing the virus strains most responsible for cervical cancer, uptake in this region remains below national targets due to socioeconomic barriers, limited healthcare access, and lack of awareness. Give Teens Vaccines is a two component intervention leveraging existing healthcare systems …


Identifying Adverse Childhood Experiences And Mental Health Needs Among A Small Sample Of Pregnant Women Who Use Cannabis, Aubrey Jones, Lisa M. Blair, Julie A. Kurzer, Kathy Rademacher, Letitia Ducas, Cynthia Cockerham, Kristin Ashford Jan 2025

Identifying Adverse Childhood Experiences And Mental Health Needs Among A Small Sample Of Pregnant Women Who Use Cannabis, Aubrey Jones, Lisa M. Blair, Julie A. Kurzer, Kathy Rademacher, Letitia Ducas, Cynthia Cockerham, Kristin Ashford

Social Work Faculty Publications

Introduction: As the legalization of cannabis becomes more widespread use has steadily increased. Approximately 5 percent of pregnant individuals self-report use during pregnancy.

Methods: This study uses a mixed methods approach to examine adverse childhood experiences, mental health needs, and cannabis use among a small sample (N =59) of women. Cumulative ACE scores of four or more were considerably high within this sample compared to the US average.

Results: Results of a binary logistic regression indicate an association between ACEs and Cannabis use (OR 1.27, 95% CI (1.002- 1.616) when controlling for maternal age and anxiety. Qualitative results identified two …


The Role Of Self-Efficacy In Rehabilitation And Recovery From Ankle Sprains, Bridget M. Walsh Jan 2025

The Role Of Self-Efficacy In Rehabilitation And Recovery From Ankle Sprains, Bridget M. Walsh

Theses and Dissertations--Rehabilitation Sciences

Ankle sprains are among the most common musculoskeletal injuries in the United States. Approximately 2 million ankle sprains occur annually, with an estimated 46% of affected individuals experiencing residual symptoms and developing chronic ankle instability (CAI). In addition to physical impairments, individuals with CAI may exhibit lower physical and psychological health-related quality of life (HRQL). HRQL integrates the physical, psychological, and social domains of a person’s health and is influenced by their experiences, expectations, and perceptions.

Injury-related fear is a common psychological impairment in individuals with CAI and has been associated with decreased physical function, reduced physical activity, and greater …


Comparison Of Laboratory Scale Bourbon Whiskey Mashing And Fermentation To Pilot Scale, Ryan C. Sarhan, Brad J. Berron, Czarena L. Crofcheck, Glenna Joyce Welsko, Tyler J. Barzee Jan 2025

Comparison Of Laboratory Scale Bourbon Whiskey Mashing And Fermentation To Pilot Scale, Ryan C. Sarhan, Brad J. Berron, Czarena L. Crofcheck, Glenna Joyce Welsko, Tyler J. Barzee

Biosystems and Agricultural Engineering Faculty Publications

Why the work was done: Laboratory scale methods are useful for optimising grain spirit production. While small scale methods exist, comparisons between conventional, simultaneous saccharification and fermentation, and distillery scale production are lacking. Further, there is limited understanding of how these methods affect the rheological properties of the mash and flavour compounds from fermentation. This study compared conventional and simultaneous saccharification and fermentation mashing methods to a pilot scale distillery to establish a standard laboratory method for simulating industrial bourbon production.

How the work was done: Two mashing methods for bourbon whiskey were compared: simultaneous saccharification and fermentation versus conventional …


Contaminant Mixtures And Their Impact On Nitrate Removal In Wetlands: A Mesocosm Study, Emily N. Byers, Tiffany L. Messer, Daniel N. Miller, Christopher Barton, Jason M. Unrine, Carmen Agouridis Jan 2025

Contaminant Mixtures And Their Impact On Nitrate Removal In Wetlands: A Mesocosm Study, Emily N. Byers, Tiffany L. Messer, Daniel N. Miller, Christopher Barton, Jason M. Unrine, Carmen Agouridis

Biosystems and Agricultural Engineering Faculty Publications

Constructed wetlands are used extensively to mitigate surface runoff. While wetland treatment for nitrogen (N) has been comprehensively studied, a knowledge gap remains regarding the implications of other contaminants (e.g., pesticides, pharmaceuticals) on nitrate-N (NO3-N) removal. This study sought to fill that gap by determining the impact imidacloprid, caffeine, perfluorooctane sulfonic acid (PFOS), atrazine, glyphosate, and sulfate (SO42−) have on NO3-N removal rates. The contaminants were determined based on their occurrence across Kentucky surface waters in urban (imidacloprid, caffeine, and PFOS) and rural (atrazine, glyphosate, and SO42−) environments. Two constructed …


Residual Next-Day Effects Of Alprazolam On Psychomotor Performance And Simulated Driving In Healthy Normal Adults, Stevie C. Roszkowski, Shanna Babalonis, Marion A. Coe, Paul Nuzzo, Michelle R. Lofwall, Laura C. Fanucchi, Sharon L. Walsh Jan 2025

Residual Next-Day Effects Of Alprazolam On Psychomotor Performance And Simulated Driving In Healthy Normal Adults, Stevie C. Roszkowski, Shanna Babalonis, Marion A. Coe, Paul Nuzzo, Michelle R. Lofwall, Laura C. Fanucchi, Sharon L. Walsh

Center on Drug and Alcohol Research Faculty Publications

The prevalence of drugged driving has increased in the United States. Some drugged driving may be unintentional as prescription medications used as sleeping aids, like zolpidem, cause impairment after the predicted duration of therapeutic action has elapsed. The aim of this study was to determine if nighttime administration of alprazolam, a drug commonly prescribed off-label as a sleeping aid, impacts driving performance the following day. Participants were healthy adults (n = 15) who completed a double-blind, double-dummy, within-subjects inpatient study examining the effects of nighttime administration of alprazolam (0.5, 1, and 2 mg), zolpidem (10 mg), and placebo on driving …


A Qualitative Study Of End-Stage Liver Disease And Liver Transplant Referral Practices Among Primary Care Providers In Nonurban America, Vashisht Madabhushi, Matthew Wright, Gabriel Orozco, Allison Murphy, Antonio R. Garcia, Natalie D. Pope, Xiaonan Mei, Alexandra Cocca, Roberto Gedaly, Meera Gupta Jan 2025

A Qualitative Study Of End-Stage Liver Disease And Liver Transplant Referral Practices Among Primary Care Providers In Nonurban America, Vashisht Madabhushi, Matthew Wright, Gabriel Orozco, Allison Murphy, Antonio R. Garcia, Natalie D. Pope, Xiaonan Mei, Alexandra Cocca, Roberto Gedaly, Meera Gupta

Surgery Faculty Publications

Purpose: In rural America, the road to obtaining a liver transplant (LTX) often starts at the primary care provider’s (PCP’s) office. Patients with end-stage liver disease (ESLD) in rural communities experience lower rates of wait-listing and higher mortality. This study identifies issues related to the knowledge and perceptions of ESLD and LTX referral among PCPs in rural Kentucky (KY).

Methods: The study protocol involved relying upon a semistructured outline to explore the knowledge, attitude, and perceptions of PCPs toward ESLD and LTX referral among PCPs in rural KY. Inductive thematic analysis was utilized to identify, analyze, and report themes.

Findings: …


A Community Effort To Develop Common Data Elements For Pre-Clinical Spinal Cord Injury Research., Britt A. Fedor, Abel Torres-Espin, Romana Vavrek, Maryann E. Martone, John L. Bixby, John C. Gensel, Vance Lemmon, Jeffrey S. Grethe, J. Russel Huie, Adam R. Ferguson, Karim Fouad, The Preclinical Sci Common Data Elements (Cde) Workshop Participants Jan 2025

A Community Effort To Develop Common Data Elements For Pre-Clinical Spinal Cord Injury Research., Britt A. Fedor, Abel Torres-Espin, Romana Vavrek, Maryann E. Martone, John L. Bixby, John C. Gensel, Vance Lemmon, Jeffrey S. Grethe, J. Russel Huie, Adam R. Ferguson, Karim Fouad, The Preclinical Sci Common Data Elements (Cde) Workshop Participants

Spinal Cord and Brain Injury Research Center Faculty Publications

For nearly 350 years, the process of disseminating scientific knowledge has remained largely unchanged. Scientists conduct experiments, analyze the data, and publish their findings in the form of scientific articles. Since the turn of the century, this process has been challenged by numerous open science and data sharing efforts to enhance transparency, reproducibility, and replicability of scientific research. Big data approaches, together with machine learning and artificial intelligence, are frequently used to gain insight into the ever-growing complexity of biological systems and biomedical research. To utilize these approaches and harness the continuously increasing computational power requires data to be both …


Cross-Species Comparisons Between Pigs And Mice Reveal Conserved Sex-Specific Intraspinal Inflammatory Responses After Spinal Cord Injury, Reena Kumari, Gabrielle V. Hammers, Robert H. Hammons, Andrew N. Stewart, Steven M. Maclean, Tracy Niedzielko, Lonnie E. Schneider, Candace L. Floyd, John C. Gensel Jan 2025

Cross-Species Comparisons Between Pigs And Mice Reveal Conserved Sex-Specific Intraspinal Inflammatory Responses After Spinal Cord Injury, Reena Kumari, Gabrielle V. Hammers, Robert H. Hammons, Andrew N. Stewart, Steven M. Maclean, Tracy Niedzielko, Lonnie E. Schneider, Candace L. Floyd, John C. Gensel

Spinal Cord and Brain Injury Research Center Faculty Publications

Objective Therapeutic translation is challenging in spinal cord injury (SCI) and large animal models with high clinical relevance may accelerate therapeutic development. Pigs have important anatomical and physiological similarities to humans. Intraspinal inflammation mediates SCI pathophysiology. The purpose of this study was to evaluate the effect of sex on inflammation and outcomes in a pig thoracic contusion/compression SCI model.

Methods Adult (gonad-intact) male and female Yucatan miniature swine were subjected to either SCI or sham (laminectomy-only) injury.

Results SCI caused locomotor dysfunction (measured with the Porcine Thoracic Injury Behavior Score) with some recovery over 6 weeks and limited tissue sparing …


Barriers To Adherence To Standard Of Care In Appalachia: A Qualitative Assessment In Gastrointestinal Cancers, Brittany Levy, Jennifer T. Castle, Roshmita Bardhan, Mark Dignan, Avinash S. Bhakta Jan 2025

Barriers To Adherence To Standard Of Care In Appalachia: A Qualitative Assessment In Gastrointestinal Cancers, Brittany Levy, Jennifer T. Castle, Roshmita Bardhan, Mark Dignan, Avinash S. Bhakta

Internal Medicine Faculty Publications

Purpose: Appalachian Kentucky, a 32-county region in the eastern part of the state, has elevated colon cancer mortality rates. While recommended as the standard of care, access to adjuvant chemotherapy treatment is limited in this region due to scarce health services and significant social and geographical barriers. The purpose of this investigation was to improve understanding of barriers that cancer patients residing in rural areas not served directly by tertiary medical systems must overcome in completing adjuvant therapy.

Methods: Participants were recruited from two medical centers: A tertiary care NCI designated Cancer Center and a regional hospital. Participants underwent a …


Circulating Molecular Drivers Of Bone Remodeling In Pancreatitis, Rachel L. Hill, Dhiraj Yadav, Phil A. Hart, David C. Whitcomb, Kristen J. Mcquerry, Kelsey N. Karnik, Kimberly M. Stello, Darwin L. Conwell, Madhumathi Rao Jan 2025

Circulating Molecular Drivers Of Bone Remodeling In Pancreatitis, Rachel L. Hill, Dhiraj Yadav, Phil A. Hart, David C. Whitcomb, Kristen J. Mcquerry, Kelsey N. Karnik, Kimberly M. Stello, Darwin L. Conwell, Madhumathi Rao

Internal Medicine Faculty Publications

INTRODUCTION: 

Pancreatitis-associated osteopathy is a clinically significant but mechanistically underexplored complication of pancreatic disease. We aimed to characterize stage-specific alterations in bone remodeling biomarkers across the spectrum of disease: recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP).

METHODS: 

In a cross-sectional analysis of North American Pancreatitis Study 2 participants, we measured serum mechanistic (sclerostin, dickkopf-1, receptor activator of nuclear factor κβ ligand, and osteoprotegerin), hormonal (fibroblast growth factor 23, insulin, and leptin), and modulatory (osteopontin, oncostatin, and osteoactivin) markers in controls (n = 30), RAP (n = 40), and CP (n = 40) using a multiplex assay. Group differences were …


Adverse Childhood Experiences, Depression And Subjective Cognitive Decline By Gender: A Moderated Mediation Analysis, Monique J. Brown, Darlingtina K. Esiaka, Jaya Viswanathan Jan 2025

Adverse Childhood Experiences, Depression And Subjective Cognitive Decline By Gender: A Moderated Mediation Analysis, Monique J. Brown, Darlingtina K. Esiaka, Jaya Viswanathan

Behavioral Science Faculty Publications

Studies assessing depression as a mediating factor between adverse childhood experiences (ACEs) and subjective cognitive decline (SCD) are lacking. Therefore, the aims of this study were to: (1) determine the mediating role of depression in the association between ACEs and SCD; and (2) assess the moderating role of gender. Data were obtained from the 2023 Behavioral Risk Factor Surveillance Study (BRFSS) survey (N = 38,600). Crude and adjusted path analyses were used to determine the mediating role of depression between ACEs and SCD. Adjusted analyses controlled for sociodemographic confounders. ACEs were positively associated with depression (B = 0.129, p …


Differential Speed And Accuracy Trade-Off In Working Memory Retrieval And Bilateral Precuneus Between Older Men And Women, Darlingtina K. Esiaka, Stephanie Strothkamp, Aghayeeabianeh Banafsheh, Lucas S. Broster, David K. Powell, Gregory Jicha, Yang Jiang Jan 2025

Differential Speed And Accuracy Trade-Off In Working Memory Retrieval And Bilateral Precuneus Between Older Men And Women, Darlingtina K. Esiaka, Stephanie Strothkamp, Aghayeeabianeh Banafsheh, Lucas S. Broster, David K. Powell, Gregory Jicha, Yang Jiang

Behavioral Science Faculty Publications

Background

Despite various hypotheses, including differences in longevity, hormones, genetics, and neuroanatomy, the reasons for the higher prevalence of Alzheimer's disease in older women compared to men remain unclear. Emerging evidence suggests that the precuneus, a key region of the default mode network, is linked to internally focused processes like memory retrieval. We examined the relationship between precuneus volumes and task performance (accuracy and reaction time) during working memory retrievals in cognitively normal older adults.

Method

A cohort of older participants (N = 45; 25 women; Mage = 77) from the University of Kentucky Alzheimer's Disease Research Center …


Disparities In Use Modalities Among Adults Who Currently Use Cannabis, 2022–2023, Meman Diaby, Osayande Agbonlahor, Bethany Shorey Fennell, Joy L. Hart, Delvon T. Mattingly Jan 2025

Disparities In Use Modalities Among Adults Who Currently Use Cannabis, 2022–2023, Meman Diaby, Osayande Agbonlahor, Bethany Shorey Fennell, Joy L. Hart, Delvon T. Mattingly

Behavioral Science Faculty Publications

Purpose

Following the legalization of cannabis in several U.S. states, the cannabis market has expanded, leading to a wider range of products including smoked, edible, and vape products which have variable health effects. This proliferation highlights the need for more research on patterns of current cannabis use among U.S. adults.

Methods

We used combined data on adults who currently use (i.e., past 30-day use) cannabis (n = 16,999) from the 2022 and 2023 National Survey on Drug Use and Health. We analyzed whether seven cannabis use modalities including smoking, vaping, dabbing, consuming edibles, taking pills, applying topicals, and absorbing …


Using Llms To Model Arguments In U.S. Supreme Court Briefs: Preliminary Report, Heng Zheng, Dexter Williams, Bertram Ludäscher Jan 2025

Using Llms To Model Arguments In U.S. Supreme Court Briefs: Preliminary Report, Heng Zheng, Dexter Williams, Bertram Ludäscher

Information Science Faculty Publications

Supreme Court briefs can impact the decision-making of Supreme Court cases. We show how to represent the briefs for a U.S. Supreme Court case as a formal argument model that relies on the briefs’ existing structure. We explore how to generate argument models with large language models (LLMs) by using them to identify attacks between arguments.


Examining The Communication Work Of Women Who Have Tested Brca-Positive: “I Feel This Responsibility To Let People Know”, Summer C. Martin, Allison M. Scott, Anne M. Stone Jan 2025

Examining The Communication Work Of Women Who Have Tested Brca-Positive: “I Feel This Responsibility To Let People Know”, Summer C. Martin, Allison M. Scott, Anne M. Stone

Communication Faculty Publications

Inheriting a pathogenic variant in the BRCA1 or BRCA2 gene considerably increases a woman's risk levels for developing breast and ovarian cancer. In addition to serious physical health implications, women with a BRCA pathogenic variant may face psychosocial challenges, including those related to navigating the often demanding process of communicating about topics regarding BRCA with family and other social network members. Based on in-depth interviews with 24 women who tested BRCA-positive, we found that—consistent with the conceptualization of communication work articulated by Donovan-Kicken et al. (2012) as an extension of the theory of illness trajectories (Corbin & Strauss, 1988)—the labor …


Cd47: An Immunoregulatory Nexus In Liver And Gastrointestinal Disorders, Josephine Otuagomah, Alana Newcomb, Taesik Gwag, Shuxia Wang Jan 2025

Cd47: An Immunoregulatory Nexus In Liver And Gastrointestinal Disorders, Josephine Otuagomah, Alana Newcomb, Taesik Gwag, Shuxia Wang

Pharmacology and Nutritional Sciences Faculty Publications

Cluster of differentiation 47 (CD47) is a widely expressed transmembrane protein that serves as a critical immunoregulatory checkpoint in both homeostatic and pathological conditions of the digestive system. It interacts with signal regulatory protein alpha to send a ‘do not eat me’ signal, thereby preventing phagocytosis and shaping immune responses. Beyond immunity, CD47 also influences cell death, growth and metabolism through interactions with integrins and thrombospondin-1. Recent studies implicate CD47 as a central nexus in the pathogenesis of diverse liver and gastrointestinal disorders, including metabolic dysfunction-associated steatotic liver disease, metabolic dysfunction-associated steatohepatitis, inflammatory bowel disease, liver ischaemia-reperfusion injury, drug-induced liver …


Barriers To And Facilitators Of Buprenorphine Dispensing For Opioid Use Disorder: Evidence From Focus Groups In Appalachian Kentucky, Douglas R. Oyler, Dustin K. Miracle, Hannah Hesener, Laura Stinson, Monica Roberts, Adrienne Matson, Patricia R. Freeman Jan 2025

Barriers To And Facilitators Of Buprenorphine Dispensing For Opioid Use Disorder: Evidence From Focus Groups In Appalachian Kentucky, Douglas R. Oyler, Dustin K. Miracle, Hannah Hesener, Laura Stinson, Monica Roberts, Adrienne Matson, Patricia R. Freeman

Pharmacy Practice and Science Faculty Publications

Background: As efforts to increase buprenorphine prescribing continue to intensify, pharmacy dispensing plays an important role in access to essential medications for opioid use disorder. Existing survey research suggests stigma and regulatory concerns are barriers to pharmacists dispensing buprenorphine, but facilitators are less clear, as are in-depth perceptions of pharmacists regarding buprenorphine.

Objective: To assess barriers and facilitators to buprenorphine dispensing in Appalachian Kentucky using a series of focus groups with pharmacy employees.

Methods: Between September and October 2023, 5 structured focus groups were conducted with a total of 19 pharmacists and pharmacy technicians across a mixture of high- and …