Digital Commons Network^™

Evaluating Experiential Learning In Undergraduate Agricultural Education: A Content Analysis Of Course Syllabi From A College Of Agriculture, Tyler Newberry

Theses and Dissertations--Community & Leadership Development

This study evaluated the presence and depth of experiential learning within undergraduate course syllabi from the Martin-Gatton College of Agriculture, Food, and Environment. Through a content analysis of 41 syllabi across five academic majors, the study examined how course objectives and assignments aligned with Kolb’s Experiential learning cycle (1984), Webb’s depth of knowledge (1997), and Joplin’s Mini to maxi Scale (1981). A structured coding instrument was used to quantify the frequency of learning elements across these three frameworks. The findings revealed that Abstract Conceptualization and Reflective Observation were the most common stages in both objectives and assignments, while Concrete Experience …

Biomedical Relation Extraction In The Era Of (Large) Language Models, Yuhang Jiang

Theses and Dissertations--Computer Science

Biomedical relation extraction is a key task in information extraction supporting downstream applications such as knowledge discovery, information retrieval, and question answering. As such, improvements in relation extraction (RE) are expected to have major implications for other information needs in biomedicine. In this dis- sertation, we pursue biomedical relation extraction in several advanced settings with recent advances in large language models (LLMs) and retrieval augmented generation (RAG). First, we address an important slot filling task on social media that arose during the Covid-19 pandemic, using the idea of continuous prompts with encoder models. Next, we handle a tricky dynamic n-ary …

Including Black Farmers, Excluding Pests: Perspectives On Participation In The Cooperative Extension Service, Briana Bazile

Theses and Dissertations--Entomology

In recent years, the U.S. Department of Agriculture has faced renewed scrutiny for documented discrimination against Black farmers, yet far less attention has focused on its century-old partner in public service delivery, the Cooperative Extension Service (CES). This gap is especially notable considering 1) federal parity mandates extant since 1972 in response to significant disparities between Black and White constituents and staff,2) public commitments to Diversity, Equity & Inclusion in 2020 and, 3) the contributions of Black leaders at the origins of CES, at Tuskegee University in the late nineteenth century. Using the Kentucky Cooperative Extension Service (KYCES) as a …

Seasonal Variation Of The Stream’S Autogenic Sediment Transport Regime, Melissa Beckman

Theses and Dissertations--Civil Engineering

This thesis investigates the autogenic sediment transport regime in a low-gradient stream system in the inner bluegrass region of central Kentucky, USA The seasonality of sediment transport seasonality was not well addressed in prior research for baseflow and low flow periods, to our knowledge, due to the assumption that low flows do not account for considerable fluid transport capacity to move sediment. The hypothesis is that during the autogenic regime the sediment transport in the low-gradient system is being driven by geophysical, biogeochemical, and biological processes. We hypothesize that crayfish are one mechanical driver of sediment transport during these periods. …

Folliculin (Flcn) In Thyroid Tumors: Incidence, Significance, And Role As A Driver Gene And Secondary Alteration, Faisal Hassan, Camryn Slone, Robert J. Mcdonald, Julie C. Dueber, Adeel M. Ashraf, Melina Windon, Oliver J. Fackelmayer, Cortney Y. Lee, Therese J. Bocklage, Derek B. Allison

Pathology and Laboratory Medicine Faculty Publications

Thyroid carcinomas are driven by diverse molecular alterations, but the tumor suppressor gene folliculin (FLCN), best known for its role in Birt–Hogg–Dubé (BHD) syndrome, has received limited attention in thyroid tumors. Here, we describe two thyroid tumors with pathogenic FLCN alterations—one germline and one somatic—and analyze the broader prevalence and significance of FLCN in thyroid carcinomas using multiple large sequencing datasets, including ORIEN-AVATAR. Patient 1, with a germline FLCN mutation and a history of BHD syndrome, presented with a well-circumscribed oncocytic adenoma. Molecular testing confirmed biallelic FLCN inactivation, but no additional mutations or aggressive features were observed, and the patient …

La Parole Comme Outil De Résistance Contre Les Tabous Oppressifs Des Femmes Marocaines : Une Étude Comparative De Paroles D’Honneur Et Hshouma, Roseline Adeleke

Students' Supported Scholarship

No abstract provided.

Effects Of Ethanol And Neuropeptide-Y Signaling On Neurogenic Markers In The Hippocampus, Cassidy Taylor Leibold

Theses and Dissertations--Psychology

According to the National Survey of Drug Use and Health in 2023, 28.9 million people over the age of 12 in the United States meet criteria for an Alcohol Use Disorder (AUD). AUDs result in a range of both social and behavioral consequences, caused by damage to the central nervous system. The hippocampus is a brain structure that undergoes cellular changes in the presence of ethanol, thus causing structural and functional damage. Impairments in neurogenesis, or the production of new neurons, due to ethanol exposure result in decreased plasticity and consequently memory impairments. The mechanisms of these ethanol-induced decreases in …

Geographic Patterns Of Human Immunodeficiency Virus (Hiv) Risk Behaviors Among Older Adults: A Strategy For Identifying Space As A Risk Exposure, Laneshia R. Conner, Reuben Adatorwovor, Sarah Jane Robbins, Rujeko O. Machinga-Asaolu, Kathryn Showalter, Carrie B. Oser

Social Work Faculty Publications

Objectives: This study examined geographical patterns of HIV risk among adults aged 60 and older.

Methods: The 2019 Behavioral Risk Factor Surveillance System (BRFSS) weighted data was used to analyze self-reported participation in HIV risk behaviors among older adults (n = 62,852). Logistic regression models were used on a dichotomous HIV risk variable to map the distribution of HIV risk behaviors across both census regions and divisions.

Results: The weighted model revealed significance across regions. Across all regions, identifying as female, identifying as Hispanic, and reporting not having depression were protective from participating in HIV risk behaviors.

Discussion: The …

Design And Comparative Analysis Of Electric Motors With “Flux-Switching” Effect Having Reluctance Rotors And Pm Or Dc Stator Excitation, Oluwaseun A. Badewa, Ali Mohammadi, Donovin D. Lewis, Somasundaram Essakiappan, Madhav Manjrekar, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

This paper introduces innovative designs for synchronous electric motors with phase coils and permanent magnets (PM) or DC-excitation coils embedded in the stator. Alongside concentrated phase coils in dedicated slots, the spoke-type PMs offer high flux intensification, while the option for DC-excitation coils eliminates demagnetization risks. Since the rotor has no active electromagnetic components, the machine can achieve high-speed operation while enabling advanced cooling systems focused solely on the stator. A special implementation with a “wave” or “serpentine” DC-excitation winding which has the potential for reduced losses depending on the motor aspect ratio is presented. The operation, control, and polarity …

Precision Public Health Alliances As A Model And Method For Community Engagement, Margaret L. Mcgladrey, Mary Elizabeth Lacy, Kristen Mcquerry, Rachel Hogg-Graham, Svetla Slavova, Emily R. Clear, Kory Heier, Caitline Phan, Megan Hall, Ryan Parker, Mindy Keeton, Jennifer Sword, Thomas Ard, Charbel Salem

Epidemiology and Environmental Health Faculty Publications

Using precision analytics approaches with population health data helps identify localized patterns of social determinants and comorbidities, supporting the design of tailored interventions. The University of Kentucky College of Public Health (UKCPH) and UK King’s Daughters (UKKD) have partnered to create a Precision Public Health Alliance (PPHA) applying precision analytics to UKKD electronic health records (EHR) as well as secondary datasets to map social, demographic, and clinical comorbidity factors onto colorectal cancer (CRC) screening data in UKKD’s rural service area (the northeastern Kentucky counties of Boyd, Carter, Greenup, and Lawrence and southeast Ohio county of Lawrence). In addition to UKKD …

Blackness And Nineteenth-Century Art In The Atlantic World, Rachel Hooper

Curatorial Publications

No abstract provided.

Listening To Cursive: The Roles Of Regional Identity And Folk Beliefs In Perceptual Cue-Weighting, Stella Takvoryan

Theses and Dissertations--Linguistics

Listeners use knowledge acquired from experiences to weight phonetic-level cues to phonological contrasts. Phonetic knowledge is imbued with expectations about the contexts in which cues covary, speakers of a variety, and identity categories or constructs, so it can be challenging to distinguish expectations about variation from expectations about speakers. This study aims to explore the extent that expectations about iconic vowel quality variation in Southern American Englishes can drive cue-weighting. Listeners categorized stimuli with vowel qualities synthesized from an [ɛ]-[eɪ] continuum from a Southern and a non-Southern talker, with duration manipulated in tandem. Half of the participants saw a label …

Common Law Executive Privilege(S), Jonathan Shaub

Law Faculty Scholarly Articles

There are few Supreme Court cases that enjoy as much widespread support as the unanimous decision in United States v. Nixon. The recent pitched battles between Congress and the executive branch have made apparent the vast disagreement between the two branches over access to information. But that disagreement does not extend to Nixon, the unquestioned jurisprudential foundation for the doctrine of executive privilege. Closer inspection shows, however, that this foundation is not a stable one, but one constructed from unnecessary, ill-considered dicta.

As this Article demonstrates, Nixon conflated the constitutional question about one branch’s power vis-à-vis another branch with an …

West Virginia V. Epa: Considerations For The Future Of Epa Greenhouse Gas Regulation, Shavonnie R. Carthens

Law Faculty Scholarly Articles

When compared to historical levels, the air quality in the United States has improved. However, exposure to air pollution still rises to the top of environmental health risks experienced by Americans. It is estimated that one hundred thousand to two hundred thousand deaths annually are associated with this exposure, which exceeds the deaths from murders and car crashes combined. Further, evidence establishes that “rising concentrations of carbon dioxide, methane, and other greenhouse gases pose serious threats to public health.” Looking to the sources of greenhouse gas emissions, fossil fuel-fired power plants are the largest source of greenhouse gas emissions in …

Three Lesser-Known African American Poets, Authors, And A Publisher In Kentucky, Reinette F. Jones

Library Faculty and Staff Publications

This article highlights the work of some lesser known historical poets who were African American, including Frances Carter DeBerry, Lawrence Harris, Sr., and Phil H. Brown.

Framing Large Language Models: Teaching Foundational Concepts Of Generative Ai And Information Literacy For Critical Student Engagement, Isaac Wink, Jennifer Hootman

Library Faculty and Staff Publications

This chapter situates the emerging scholarly conversation around AI literacy within the established Association for College and Research Libraries (ACRL) Framework for Information Literacy for Higher Education. We apply three frames in particular: 1) Authority Is Constructed and Contextual, 2) Information Creation as a Process, and 3) Research as Inquiry, considering competencies relevant to students encountering generative AI applications in educational contexts and addressing ways that both students and instructors may seek to engage productively with such tools.

This chapter primarily focuses on tools such as ChatGPT that are built atop large language models (LLMs)—systems trained on massive text corpora—rather …

West Virginia V. Epa: Consideration For The Future Of Epa Greenhouse Gas Regulation, Shavonnie R. Carthens

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

In this article, Shavonnie Carthens examines the implications of West Virginia v. EPA, emphasizing how the Supreme Court’s use of the major questions doctrine creates uncertainty around the Environmental Protection Agency’s (“EPA”) authority to regulate greenhouse gas emissions. It argues that, in light of the doctrine’s growing influence and the end of Chevron deference, Congress should revise the Clean Air Act to explicitly authorize the EPA to regulate greenhouse emissions through system-based transitions to cleaner power-generating sources, public health-conscious considerations, and multi-agency regulatory approaches to ensure durable and effective climate policy.

Quieting The Cacophony: How To Reduce Greenwashing And Environmental Damage From The Food Industry, Alex Woodward

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

In this article, Alex G. Woodward addresses the problem of greenwashing and environmental harm caused by industrial agriculture and misleading food labeling. Woodward explains that while agriculture is essential to feeding a growing global population, its large-scale, profit-driven practices cause significant environmental damage. Woodward argues for a strategy that compels transparency through warning labels and expanding credible certification frameworks. Woodward proposes that the USDA implement a tiered labeling system under its Organic Program and require factual, noncontroversial disclosures about environmental harms on food packaging, with the goal of informing consumers, restoring trust, and incentivizing environmentally responsible agricultural practices.

This Land Is Our Land: Addressing Foreign Ownership Of Agricultural Land In The United States, Will Miller

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

In this note, Will Miller examines the rapid increase in foreign ownership of U.S. agricultural land and the national security and food security risks it creates. He explains that the Agricultural Foreign Investment Disclosure Act (AFIDA) only requires reporting of foreign ownership but imposes no restrictions, leaving regulation largely to a patchwork of state laws. Miller argues for federal oversight, contending that matters of foreign affairs and national security are best handled at the national level. He proposes a comprehensive federal regulatory scheme which would set nationwide minimum standards such as prohibiting ownership by foreign adversaries and capping total foreign-held …

Pesticide Lies! A Call For Epa Action As Recent Judicial Decisions Reveal The Harmful Truth Resulting From Exposure, Stevi Whitman

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

In this note, Stevi Whitman analyzes the dangers of weak pesticide regulation in the United States. Whitman explains that the EPA’s reliance on the vague “unreasonable adverse effects” standard under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) allows harmful products like Roundup to remain on the market despite strong evidence of health risks. Whitman argues for strengthening U.S. pesticide laws to match the European Union’s stricter safety threshold. She proposes amending FIFRA to require proactive bans on hazardous pesticides and greater accountability from manufacturers to better protect public health and the environment.

The New American Farmer – Extension Engagement With Urban Agriculture And Food Systems, Margaux S.C. Robinson, Kc V. Cunningham, Jeffery A. Young, Nicole D. Breazeale, Kenneth Jones, Julie Zimmerman

Sociology Faculty Publications

Extension's evolving role in urban food production will require intensive reflexivity and ongoing collaboration. Extension educators around the country have already made progress in engaging with both the social and horticultural sides of urban agriculture. Designed appropriately, urban food systems hold the potential for healthy food access, community and environmental resilience, and economic prosperity (Rangarajan & Riordan 2019). Moving forward, we offer recommendations for Extension staff to apply within their institutions and beyond. Specifically, we urge Extension to prioritize the following: 1) mediate the rural/urban dichotomy, 2) tackle structural and institutional power dynamics, and 3) intensify strategies for community resilience.

Two-Level Multi-Objective Design Optimization Including Torque Ripple Minimization For Stator Excited Synchronous And Flux Switching Machines, Ali Mohammadi, Oluwaseun A. Badewa, Yaser Chulaee, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Electric machine performance can be enhanced through torque ripple mitigation, which reduces mechanical vibrations and improves system stability and operation. This paper proposes a novel two-level optimization method for synchronous flux-switching and hybrid excitation machines, featuring an innovative multi-point spline shaping approach for torque ripple minimization. The study employs experimentally validated models based on a prototype with a similar topology. The optimization process is implemented on two distinct designs: a 20-pole inner rotor PM-excited stator machine and a 28-pole outer rotor DC-excited stator machine. Analysis results demonstrate that the proposed innovative method significantly reduces torque ripple in both configurations. Force …

Ai In Newsrooms: Assessing Perception, Challenges And Possibilities In Bangladesh’S Media Landscape, Nadia Rahman

Theses and Dissertations--Communication

With the relentless progression of technological advancements, artificial intelligence (AI) has become a transformative force across various sectors, and newsrooms are no exception. Developed nations have already integrated AI into journalistic practices, showcasing its versatility in different news functions. However, the developing nations, including Bangladesh, a south Asian nation faces challenges in catching up, marked by technological and economic disparities. As an emerging economic force Bangladesh encounters different obstacles in the adoption of AI in its media landscape. Despite the expansiveness of its media industry, the country grapples with limited technological support and inadequate training opportunities. These challenges bring up …

Black Love, Media Portrayals, And Social Identity, Nigel M. Taylor

Theses and Dissertations--Communication

This dissertation explores how media stereotypes about Black relationships influence Black individuals' perceptions, shaping their understanding and expectations of love. Using social identity theory as a foundation, a mixed-methods approach integrates both qualitative and quantitative methods to examine the impact of media portrayals on self-concept and relationship expectations. The quantitative findings investigate connections between media exposure, self-esteem, and partner preferences, revealing how media shapes ideas about ideal relationships and internalized racial dynamics. The qualitative analysis identifies seven themes that define Black Love and seven themes that depict media stereotypes of Black relationships. The study shows that while media often reinforce …

Going Inside A Church Staff Group: A Qualitative Case Analysis Of Team Characteristics, Decision-Making, And Identity, Hillary Rose Hamilton

Theses and Dissertations--Communication

Many organizations, including churches, rely on leadership groups to coordinate efforts and fulfill their mission. Guided by the characteristics of highly effective teams, the functional theory of group decision-making, and symbolic convergence theory, this study examines how one church staff group engages in decision-making and enacts identity through socioemotional and task-related communication. This group is unique in that its members each lead different areas necessary for the church’s functioning. Data for this qualitative case-study consists of semi-structured interviews with each group members and five meeting observations. Findings provide insight into the group’s dynamics, decision-making process, and identity. However, of most …

Chemoproteomic Profiling Of A Carbon-Stabilized Gold(Iii) Macrocycle Reveals Cellular Engagement With Hmox2, Sailajah Gukathasan, Chibuzor Ngozi Olelewe, Libby Ratliff, Jong H. Kim, Alyson M. Ackerman, J. Robert Mccorkle, Sean Parkin, Gunnar F. Kwakye, Jill M. Kolesar, Samuel G. Awuah

Chemistry Faculty Publications

In this work, we discovered a novel organometallic gold(III) macrocycle, Au-Mac1, that demonstrates anticancer potency in a panel of triple-negative breast cancer cells (TNBC), and based on this complex, a biotinylated-Au-Mac1 probe was designed for target identification via chemoproteomics, which uncovered the engagement of HMOX2 of the heme-energy metabolism pathway. Using orthogonal chemical biology and molecular biology approaches, including immunoblotting, flow cytometry, and cellular thermal shift assays, it was confirmed that Au-Mac1 engages HMOX2 in cells. Downstream effects of Au-Mac1 on the depletion of mitochondrial membrane proteins and bioenergetics point to the potential role of HMOX2 in cancer. Importantly, Au-Mac1 …

Electrochemical Observation And Ph Dependence Of All Three Expected Redox Couples In An Extremophilic Bifurcating Electron Transfer Flavoprotein With Fused Subunits, Debarati Das, Wassim El Housseini, Monica Brachi, Shelley D. Minteer, Anne-Frances Miller

Chemistry Faculty Publications

Bifurcating enzymes employ energy from a favorable electron transfer to drive unfavorable transfer of a second electron, thereby generating a more reactive product. They are therefore highly desirable in catalytic systems, for example, to drive challenging reactions such as nitrogen fixation. While most bifurcating enzymes contain air-sensitive metal centers, bifurcating electron transfer flavoproteins (bETFs) employ flavins. However, they have not been successfully deployed on electrodes. Herein, we demonstrate immobilization and expected thermodynamic reactivity of a bETF from a hyperthermophilic archaeon, Sulfolobus acidocaldarius (SaETF). SaETF differs from previously biochemically characterized bETFs in being a single protein, representing a …

Development Of A Ghrelin Deacylase To Attenuate Drug Reward And Associated Effects Of Methamphetamine, Madeline J. Stewart, Huimei Wei, Nellore Bhanu Chandar, Fang Zheng, Chang-Guo Zhan

Pharmaceutical Sciences Faculty Publications

All addictive substances directly or indirectly interact with the dopamine reward system to alter the brain’s dopamine receptor activities. It is essential for a truly effective addiction medication to attenuate substance reward and normalize the brain’s physiological functions. Conventional pharmacological intervention approaches to the treatment of substance addiction usually aim to develop and deliver a potential therapeutic agent to the brain to directly block or decrease actions of the substance or its therapeutic target in the brain. However, it is a grand challenge to attenuate the substance reward without affecting the normal physiological functions of brain receptors or transporters. Here, …

Effects Of Fentanyl-Laced Cocaine On Circulating Ghrelin, Insulin, And Glucose Levels In Rats, Huimei Wei, Elise C. Maul, Annet Kyomuhangi, Shawn Park, Maddilynn L. Mutchler, Chang-Guo Zhan, Fang Zheng

Pharmaceutical Sciences Faculty Publications

Opioid mixed with cocaine has been increasingly implicated in overdose deaths, including both intentional co-use of opioid and cocaine and fentanyl-adulterated drug supply. As ghrelin plays an important role in drug reward and can also influence insulin, this study aimed to assess responses of the circulating ghrelin, insulin, and glucose levels to the combined use of fentanyl and cocaine (a polydrug) in rats by performing combined animal behavioral experiments and biochemical analysis. The experimental data consistently revealed that the fentanyl and cocaine co-use can significantly elevate both the acyl-ghrelin and desacyl-ghrelin levels and significantly decrease the insulin level without significant …

Development Of Zafirlukast Analogues For Improved Antithrombotic Activity Through Thiol Isomerase Inhibition, Justine A. Keovilay, Kaitlind C. Howard, Kirk A. Taylor, Sabeeya Khan, Sienna E. Wurl, Melanie K. Szahaj, Tanya Sage, Nishad Thamban Chandrika, Caixia Hou, Oleg V. Tsodikov, Jonathan M. Gibbins, Sylvie Garneau-Tsodikova, Daniel R. Kennedy

Pharmaceutical Sciences Faculty Publications

Background:   Thiol isomerases play essential and nonredundant roles in platelet activation, aggregation, and thrombus formation. Thiol isomerase inhibitors have the potential to overcome the 2 major drawbacks of current antithrombotic therapies, as they target both arterial and venous thrombosis without enhancing bleeding risks. Recently, a Food and Drug Administration–approved drug, zafirlukast (ZAF), was shown to be a promising pan-thiol isomerase inhibitor. The objective of this study is to develop analogues of ZAF with optimized thiol isomerase inhibition and antithrombotic activity.   Methods:   Thirty-five ZAF analogues were tested in an insulin turbidometric assay for thiol isomerase inhibition. Analogues were tested for platelet …