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Relations Between Nitrogen Fertilization, Herbage Production And Milk Yield, E A. Lantinga, L T'Mannetje, H Schlepers Oct 2025

Relations Between Nitrogen Fertilization, Herbage Production And Milk Yield, E A. Lantinga, L T'Mannetje, H Schlepers

IGC Proceedings (1977-2023)

The response to N-fertilizer of animal output and of herbage production was compared. There appeared to be no difference in the responses to applied nitrogen between intensive continuous grazing and weekly cutting in the range of 300 to 500 kg N/ha/yr. It is hypothesized that the response to applied nitrogen in a continuously grazed sward is mainly determined by the intensity of grazing and that the benefit from nitrogen circulation through excreta has little meaning for the pasture as a whole.

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Modelling Grazing Intensity Studies, David I. Bransby Oct 2025

Modelling Grazing Intensity Studies, David I. Bransby

IGC Proceedings (1977-2023)

Grazing intensity models have traditionally related animal production per head and per ha to stocking rate. The value of such models is limited by the omission of pasture information. In this paper the relationships between average daily gain, grazing days and standing herbage are used to develop models relating animal production per ha to standing herbage. These models can also be extended by relating changes in their parameters to additional quantifiable variables, or by using them in economic models to express profit per ha in terms of standing herbage.

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Coping With Grazing: A Comparison Of Two Savanna Grasses Differing In Tolerance To Defoliation, K C. Hodgkinson, J J. Mott, M M. Ludlow Oct 2025

Coping With Grazing: A Comparison Of Two Savanna Grasses Differing In Tolerance To Defoliation, K C. Hodgkinson, J J. Mott, M M. Ludlow

IGC Proceedings (1977-2023)

Heavy grazing by cattle, resulting from various practices to intensify carrying capacity, is reducing the abundance of the dominant Kangaroo grass (Themeda australis) in Australia's tropical and subtropical savannas. The objective of this study was to find whether morphological and/or physiological factors were the cause oflow tolerance of T. australis to heavy grazing. Themeda australis was compared in a glasshouse experiment, with buff el grass ( Cenchrus ciliaris), a successful introduction from Africa and known to be grazing tolerant. Half the plants were subjected to frequent close defoliation and their regrowth was compared with infrequently defoliated plants. …

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Heat Production Of Free Grazing Cattle, K Ochiai, I Tahata, F Andoh, S Shioya, T Ami Oct 2025

Heat Production Of Free Grazing Cattle, K Ochiai, I Tahata, F Andoh, S Shioya, T Ami

IGC Proceedings (1977-2023)

Heat production and herbage intake of housed and free grazing cattle were examined using trachea cannulea oxygen consumption measuring system. The daily heat production of Holstein steer and Japanese Black cow grazing on orchardgrass pasture were 212 and 167 kcal/BW0•75/day, respectively. These figures were 56% and 37% greater than those of housed cattle. The daily herbage intake of the Japanese Black cow were 64 and 77 DMg/BW°·75/day in housed and grazing, respectively. And those of the Holstein steer were 69 and 149 DM/BW°·75/day. Regarding the behaviour of cattle, the highest heat production rate was observed in grazing activity, and lowest …

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Thermoregulatory Behaviour And The Skin Temperature Of Grazing Cattle, M Sakurai, H Dohi Oct 2025

Thermoregulatory Behaviour And The Skin Temperature Of Grazing Cattle, M Sakurai, H Dohi

IGC Proceedings (1977-2023)

In order to clarify the thermoregulatory behaviour in hot and frosty environment, the skin temperature of the Japanese Black Cattle in the pasture was measured by a handy radiation thermometer. The regression equation of the temperature (X) and the skin temperature (Y) of grazing cattle was Y=0.814X+ 11.57 (regression coefficient; r=0.972), and that of the direct solar radiation (X) and the skin temperature (Y) was Y=18.05X+30.62 (r=0.824). When the skin temperature rose beyond about 40°C on sunny and hot days in summer, the cattle began to shelter in shade, where the skin temperature went down to about 35°C. When the …

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Immune Response Of Grazing Cattle To Rumen Microflora, K Ogimoto, S Sato, T Inamoto Oct 2025

Immune Response Of Grazing Cattle To Rumen Microflora, K Ogimoto, S Sato, T Inamoto

IGC Proceedings (1977-2023)

Changes in immune response to several rumen bacterial species were investigated in grazing cattle. The results revealed immune response variation in cattle from the first and second grazing seasons. Agglutination titers in sera to Streptococcus bovis and Butyrivibrio fibrisolvens increased after 30 days of grazing. Those of S. bovis remained at a higt level until grazing was competed, while titers of B. fibrisolvens were maximum after 45 days and gradually decreased. Changes in agglutinating titers to both bacterial species varied greatly in cattle of the first grazing season. Titers of Ruminococcus albus were similar to the above two species, …

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Vegetational Changes In The Sasa Nipponica Grassland Used By Winter Grazing For Successive Years, Y Ogawa, T Mitamura, K Okamoto Oct 2025

Vegetational Changes In The Sasa Nipponica Grassland Used By Winter Grazing For Successive Years, Y Ogawa, T Mitamura, K Okamoto

IGC Proceedings (1977-2023)

The influence of winter grazing by beef cattle on yearly yield and flora changes in Sasa (Sasa nipponica) grassland was examined from 1974 to 1982. This Sasa sward was established semi-naturally on cutover land following deciduous broadleaved forest at an altitude of 1,100 m on Mt. Asama in Japan. Sasa kept its foliage green and nutritive all year round, so that in this experimental grassland a large quantity of its foliage supplied sufficient nutrients for the maintenance of beef cows during winter grazing periods. Foliage weight was 2.6 tons DW/ha before winter grazing use and this value was maintained for …

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Intensive Use Of Young Japanese Cedar Forest For Grazing, K Sugawara, T Isawa, M Goto, I Ito Oct 2025

Intensive Use Of Young Japanese Cedar Forest For Grazing, K Sugawara, T Isawa, M Goto, I Ito

IGC Proceedings (1977-2023)

Experiments were conducted to investigate the intensive forest grazing in young Japanese cedar forest by introducing improved pasture species to forest floor. Study area (1-year old Japanese cedar forest) was divided into three treatment plots; unseeded and unfertilized ( unseeded plot), seeded with nitrogen (N)- phosphorus (P)-potassium (K) fertilizer ( seeded-NPK plot) and seeded with twice amount of fertilizer ( seeded-2NPK plot). Herbage production, grazing capacity, injury to the tree by grazing cattle and growth of the tree were compared among the treatments. The mean of annual fresh matter yield was 11.6 t/ha at unseeded plot, 12.7 t/ha at seeded-NPK …

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Reforestation And Cattle Grazing In Southern United States, Henry A. Pearson Oct 2025

Reforestation And Cattle Grazing In Southern United States, Henry A. Pearson

IGC Proceedings (1977-2023)

This research was undertaken to learn if cutover southern pine ranges can be sucessfully regenerated artificially with slash pine (Pinus elliottii Engelm.) while being grazed yearlong by beef cattle, Objectives were to determine the effects of various grazing intensities on the establishment and growth of slash pine and on herbage and cattle production, and the subsequent influence of pines on herbage and cattle production. Three range units comprising about 650 ha of cutover pine land were stocked to produce light, moderate, and heavy grazing intensities. Each year during a 4-year regeneration cycle, 17 percent of each range unit was …

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Improvement Of Forest Grazing On Sado Island, H Hirota, T Suzuki Oct 2025

Improvement Of Forest Grazing On Sado Island, H Hirota, T Suzuki

IGC Proceedings (1977-2023)

The develpoment of forest grazing in Sada Island is briefly outlined and the cause of the abrupt decline of Zoysia dominant vegetation during the last few decades is discussed. Some experimental results to improve the herbage production for forest grazing on the island are described. For example the invading bush trees should be controlled by either felling them down or applying herbicides, followed by vegetative propagation of Zoysia species and fertilizer application. Gentle slopeland can be renovated by oversowing cool temperate grass species; 15 Kg Dactylis glomerata, 10 Kg Lolium perenne, 5 Kg Paa pratensis and 5 Kg …

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Grazing As A Part Of Agroforestry, Harold F. Heady Oct 2025

Grazing As A Part Of Agroforestry, Harold F. Heady

IGC Proceedings (1977-2023)

Multiple use of land by the small landholder for food crops, trees and animals, often called agroforestry, holds great promise for aiding people near poverty in developing countries, but new forages and techniques of management must be developed.

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Forest Grazing In Taiwan, M D. Huang, K J. Chen, Y J. Wu, J C. Yang Oct 2025

Forest Grazing In Taiwan, M D. Huang, K J. Chen, Y J. Wu, J C. Yang

IGC Proceedings (1977-2023)

Due to the shortage of man-power in rural regions, forest grazing was tested as an alternative to eliminate the noxious plants dispersed on the timber plantations in Taiwan. Tree growth was not affected, when Hereford heifers were introduced to 4-year-old Taiwania cryptomerioides plantations(at 1,600 m altitude). Although indigenous water buffaloes were less tolerant to heat than the European cattle( Hereford and Holstein), they were able to show moderate body weight gain in the tough forest environment. Partial blood profiles obtained from buffaloes and cattle gave the same conclusion.

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Effects Of Spring Mangement On Herbage Mass And Sward Characteristics In Ryegrass White Clover Pasture, B M. Butler, A.C P. Chu, P.N P. Mathews, C J. Korte Oct 2025

Effects Of Spring Mangement On Herbage Mass And Sward Characteristics In Ryegrass White Clover Pasture, B M. Butler, A.C P. Chu, P.N P. Mathews, C J. Korte

IGC Proceedings (1977-2023)

The effects of grazing intensity and frequency were investigated on a ryegrass/white clover pasture. Large differences in herbage mass between treatments arose mostly from ryegrass reproductive stubble during spring and mid-summer and from dead reproductive stubble during mid-summer and early autumn. Leafy, vegetative pastures were achieved during the reproductive growth period by maintaining a sward residual of less than 500 kg leaf DM/ha (sward height 9 cm) and a grazing interval of less than 14 days (pre-grazing height 20 cm). The evidence suggests that reducing the mass or size of individual reproductive tillers can be equally effective as that of …

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Biotechnology In The Improvement Of Forage Crops, Indra K. Vasil Oct 2025

Biotechnology In The Improvement Of Forage Crops, Indra K. Vasil

IGC Proceedings (1977-2023)

Major advances in the cellular and molecular biology of plants recently have created new opportunities for the application of the many novel methods of biotechnology to the genetic modification and improvement of crop plants. The techniques of plant cell culture, particularly those allowing the regeneration of plants from single cells, play an important and integral role in the various strategies currently being pursued for plant improvement by unconventional means. In the past, initiation and maintenance of, as well as plant regeneration from, tissue cultures of species of the Gramineae (Poaceae) proved to be difficult. Nevertheless, cultures capable of plant regeneration …

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Present State Of Grassland Production And Utilization And Future Perspectives For Grassland Farming In Humid Tropical Asia, I M. Nitis Oct 2025

Present State Of Grassland Production And Utilization And Future Perspectives For Grassland Farming In Humid Tropical Asia, I M. Nitis

IGC Proceedings (1977-2023)

Forage in humid tropical Asia consists of natural pasture, crop residues, shrub and tree leaves. Reserch has shown that the yield and quality of such forage can be increased and performance of the livestock utilizing such forage can be improved. Grassland farming contributes to the feed supply for livestock, to conservation, and is one component of an integration, which may increase economic returns and maintain the ecological balance of the region. Future research emphases on companion cropping, three strata forage, development of tidal flooding areas, agroforestry, carbon/nitrogen cyling, pasture persistency, seed production, post harvest, forage utilization and farming modelling are …

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Grassland Resources And Future Development Of Grassland Farming In Temperate China, Zhu Tingcheng, Li Jiandong, Zu Yuangang Oct 2025

Grassland Resources And Future Development Of Grassland Farming In Temperate China, Zhu Tingcheng, Li Jiandong, Zu Yuangang

IGC Proceedings (1977-2023)

In the first part of the paper the grassland resources in the semiarid area of China are descrived. Grasslands cover 2.86 million km2 of the total territory and 100 million livestock are being raised there. Steppes and meadows are classified into several types according to the ecological types of the dominant species and environments, etc. Area, geographical distribution, community structure, species composition, dynamics, nutritive value of herbages, primary production and utilization of each grassland type are outlined. In the second part, the necessity to promote grassland farming and the possibility of its development are discussed based upon the land, population, …

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An Interdisciplinary Approach For Increasing Yield And Improving Quality Of Forages, J R. Wilson Oct 2025

An Interdisciplinary Approach For Increasing Yield And Improving Quality Of Forages, J R. Wilson

IGC Proceedings (1977-2023)

The contribution of some basic plant disciplines, principally physiology and histology, to the improvement of pasture yield and quality is discussed. Studies of temperate pasture grasses have identified several sources of loss of potential yield and have provided selection criteria for increasing yield. Integration of this physiological research with studies of forage consumption on the same pastures is proving a valuable inter- disciplinary approach to defining management options for maximising pasture and/or animal productivity. In tropical grasses, research towards increasing total dry matter yield is perhaps unwarranted but there is need for more co-operative studies involving plant and animal scientists …

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Contribution Of Grassland Science To The Development Of Forage Production And Future Perspectives For Grassland Farming In Japan, H Oizumi Oct 2025

Contribution Of Grassland Science To The Development Of Forage Production And Future Perspectives For Grassland Farming In Japan, H Oizumi

IGC Proceedings (1977-2023)

The utilization of grassland in Japan dates to fairy old times, but its real improvement in terms of industry did not start until the termination of the World War II. As the climatic conditions in Japan differ very much from those of European coutries, the style of grassland farming in Japan is somewhat different from that of Europe. The improvement of grassland farming in Japan after the World War II was divided into four stages, according to the tendency of the number of cattle and the acreage of forage crops. The Japanese Society of Grassland Science was established in 1954. …

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Prospects For Increasing Symbiotic Nitrogen Fixation In Temperate Grasslands, P/ Roger Ball, J R. Crush Oct 2025

Prospects For Increasing Symbiotic Nitrogen Fixation In Temperate Grasslands, P/ Roger Ball, J R. Crush

IGC Proceedings (1977-2023)

The contribution of some basic plant disciplines, principally physiology and histology, to the improvement of pasture yield and quality is discussed. Studies of temperate pasture grasses have identified several sources of loss of potential yield and have provided selection criteria for increasing yield. Integration of this physiological research with studies of forage consumption on the same pastures is proving a valuable inter- disciplinary approach to defining management options for maximising pasture and/or animal productivity. In tropical grasses, research towards increasing total dry matter yield is perhaps unwarranted but there is need for more co-operative studies involving plant and animal scientists …

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Candida Auris Screening, Positivity Trends, And Patient Characteristics At The University Of Kentucky Between 2021 And 2024, Faith Fursman, Natalie Fitzsimmons, Da Nelle Overton, Court Desmond, Kimberly Blanton, Kevin W. Hatton, Rachel Howard, David Olafsson, Sean Mctigue, Nicholas Van Sickels, Derek Forster, Takaaki Kobayashi Oct 2025

Candida Auris Screening, Positivity Trends, And Patient Characteristics At The University Of Kentucky Between 2021 And 2024, Faith Fursman, Natalie Fitzsimmons, Da Nelle Overton, Court Desmond, Kimberly Blanton, Kevin W. Hatton, Rachel Howard, David Olafsson, Sean Mctigue, Nicholas Van Sickels, Derek Forster, Takaaki Kobayashi

Surgery Faculty Publications

We evaluated a targeted Candida auris screening program, which revealed a 0.96% positivity rate. The proportion of community-onset cases increased from 8% to 54% following implementation. No significant differences in demographic or clinical characteristics were observed between patients with colonization and those with infection.

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Precision Assessment Of Facial Asymmetry Using 3d Imaging And Artificial Intelligence, Mohamed Adel, Katie Jo Hunt, Daniel Lau, James K Hartsfield, Hugo Reyes-Centeno, Cynthia S Beeman, Tarek Elshebiny, Lina Sharab Oct 2025

Precision Assessment Of Facial Asymmetry Using 3d Imaging And Artificial Intelligence, Mohamed Adel, Katie Jo Hunt, Daniel Lau, James K Hartsfield, Hugo Reyes-Centeno, Cynthia S Beeman, Tarek Elshebiny, Lina Sharab

Anthropology Faculty Publications

Objectives: There is a growing interest among practitioners in employing artificial intelligence (AI) to enhance the precision and efficiency of diagnostic methods. The objective of this study is to assess the precision of an AI-based method for facial asymmetry assessment using 3D facial images. Methods: The study included 130 patients (84 female, 46 male), analyzing 3D facial images from the Vectra ® M3 imaging system using both manual and AI-based methods. Seven bilateral facial landmarks were identified for manual analysis, calculating the asymmetry index for facial symmetry assessment. An AI-based program was developed to automate the identification of the same …

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Do Honey Phytochemicals Modulate Forager Aggression And The Gut Microbiome In The Honey Bee (Apis Mellifera L.)?, Wade A. Pike, Jaesylin Stephens, Mariah Donohue, Katsuri Rajandran, Erin D. Tranore, Abdallah Sher, Emily Croteau, Clare C. Rittschof Oct 2025

Do Honey Phytochemicals Modulate Forager Aggression And The Gut Microbiome In The Honey Bee (Apis Mellifera L.)?, Wade A. Pike, Jaesylin Stephens, Mariah Donohue, Katsuri Rajandran, Erin D. Tranore, Abdallah Sher, Emily Croteau, Clare C. Rittschof

Biology Faculty Publications

Plant phytochemicals found in nectar impact bee learning and memory and plant pollination success. Especially for generalist pollinators, dietary changes that alter phytochemical consumption could be common sources of behavioral variation. For honey bee (Apis mellifera L.) foragers, a major potential change in phytochemical consumption occurs when individuals switch from collecting nectar from flowers to collecting honey from neighboring colonies, a phenomenon known as honey robbing. In this study we investigated whether phytochemicals dominant in honey compared to nectar act as a short-term trigger of robbing behaviors in honey bee, which include increased aggression. We fed forager honey bees sucrose …

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Estimating (Non)Linear Selection On Reaction Norms, Jordan S. Martin, Yimen G. Araya-Ajoy, Niels J. Dingemanse, Alastair J. Wilson, David F. Westneat Oct 2025

Estimating (Non)Linear Selection On Reaction Norms, Jordan S. Martin, Yimen G. Araya-Ajoy, Niels J. Dingemanse, Alastair J. Wilson, David F. Westneat

Biology Faculty Publications

Individual reaction norms describe how labile phenotypes vary as a function of organisms' expected trait values (intercepts) and plasticity across environments (slopes), as well as their degree of stochastic phenotypic variability or predictability (residuals). These reaction norms can be estimated empirically using multilevel, mixed-effects models and play a key role in ecological research on a variety of behavioral, physiological, and morphological traits. Many evolutionary models have also emphasized the importance of understanding reaction norms as a target of selection in heterogeneous and dynamic environments. However, it remains difficult to empirically estimate nonlinear selection on reaction norms, inhibiting robust tests of …

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Estrogen Signaling Is Necessary For The Sex Difference In Simulated Jet Lag In Mice, Maria A. Venegas, Nicholas Westray, Samuel Nwadialo, Yuriko Katsumata, Julie S. Pendergast Oct 2025

Estrogen Signaling Is Necessary For The Sex Difference In Simulated Jet Lag In Mice, Maria A. Venegas, Nicholas Westray, Samuel Nwadialo, Yuriko Katsumata, Julie S. Pendergast

Biology Faculty Publications

The circadian system coordinates 24-h cycles of internal biological processes with the environmental light-dark cycle. Abrupt shifts in the timing of the light-dark cycle misalign internal circadian clocks with the environment and cause jet lag until resynchronization occurs. The objective of this study was to investigate the sex difference in simulated jet lag in mice. Female mice resynchronized faster than male mice to 6-h advances of the light-dark cycle that mimicked eastward travel. Circulating estradiol was necessary and sufficient for rapid resynchronization in female mice since ovariectomized females resynchronized slower than mice treated with estradiol. Disabling estrogen receptor a (ERa), …

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Mechanical Distention Of Organotypic Hippocampal Slice Culture Membranes For High-Throughput In Vitro Modeling Of Traumatic Brain Injury, Julia Jagielo-Miller, Caleb Bailey, Samir Patel, Paresh Prajapati, Cassidy Leibold, Patrick Sullivan, Mark Prendergast Oct 2025

Mechanical Distention Of Organotypic Hippocampal Slice Culture Membranes For High-Throughput In Vitro Modeling Of Traumatic Brain Injury, Julia Jagielo-Miller, Caleb Bailey, Samir Patel, Paresh Prajapati, Cassidy Leibold, Patrick Sullivan, Mark Prendergast

Biology Faculty Publications

Traumatic brain injury (TBI) results from impact to the head that induces both primary and secondary injuries. Secondary injuries are characterized by downstream inflammation, metabolic dysfunction, and cell death manifest from the inflicting primary injury to the head. Secondary injury offers a window for therapeutic interventions, but the multifaceted nature of secondary injury is complicated, necessitating mechanistic tools to screen the efficacy of such interventions. As such, utilizing animal models to define the features of secondary injury mechanisms is critical for medications development. Various animal TBI models employ specialized equipment to recapitulate both primary and secondary injury aspects of human …

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Remote Sensing Of American Revolutionary War Fortification At Butts Hill (Portsmouth, Rhode Island), James G. Keppeler, Marcus Rodriguez, Samuel Koontz, Alexander Wise, Philip Mink, George Crothers, Paul R. Murphy, John K. Robertson, Hugo Reyes-Centeno, Alexandra Uhl Oct 2025

Remote Sensing Of American Revolutionary War Fortification At Butts Hill (Portsmouth, Rhode Island), James G. Keppeler, Marcus Rodriguez, Samuel Koontz, Alexander Wise, Philip Mink, George Crothers, Paul R. Murphy, John K. Robertson, Hugo Reyes-Centeno, Alexandra Uhl

Anthropology Faculty Publications

The Battle of Rhode Island in 1778 was an important event in the revolutionary war leading to the international recognition of U.S. American independence following the 1776 declaration. It culminated in a month-long campaign against British forces occupying Aquidneck Island, serving as the first combined operation of the newly formed Franco-American alliance. The military fortification at Butts Hill in Portsmouth, Rhode Island, served as a strategic point during the conflict and remains well-conserved today. While LiDAR has assisted in the geospatial surface reconstruction of the site’s earthwork fortifications, it is unknown whether other historically documented buildings within the fort remain …

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Rrad-Reduction Reveals Efficacy Of Targeting L-Type Calcium Channel Regulation For Treatment Of Heart Failure, Garrett Elmore, Sarisha S. Lohano, Nicholas M. Mcvay, Bryana M. Levitan, Andrea Sebastian, Kyle W. Barker, Alec Dupont, Steven W. Leung, Riham R.E. Abouleisa, Pretty R. Mathew, Austin Wellette-Hunsucker, Austin T. Minton, Kenneth S. Campbell, Solomon W. Harrar, Mohammad Mehri, Jonathan F. Wenk, Tamer M.A. Mohamed, Douglas A. Andres, Jonathan Satin Oct 2025

Rrad-Reduction Reveals Efficacy Of Targeting L-Type Calcium Channel Regulation For Treatment Of Heart Failure, Garrett Elmore, Sarisha S. Lohano, Nicholas M. Mcvay, Bryana M. Levitan, Andrea Sebastian, Kyle W. Barker, Alec Dupont, Steven W. Leung, Riham R.E. Abouleisa, Pretty R. Mathew, Austin Wellette-Hunsucker, Austin T. Minton, Kenneth S. Campbell, Solomon W. Harrar, Mohammad Mehri, Jonathan F. Wenk, Tamer M.A. Mohamed, Douglas A. Andres, Jonathan Satin

Surgery Faculty Publications

Aims Heart failure with reduced ejection fraction (HFrEF) is a major health problem. Increasing L-type calcium channel (LTCC) activity deteriorates heart function; however, myocardial RRAD knockout (cRADΔ/Δ) instills tonic modulated LTCC current (ICa,L) that preserves healthy myocardium. Thus, we chose to challenge the dogma that enhanced trigger Ca2+ is maladaptive. The study objective was to test the hypothesis that modulated ICa,L in cRADΔ/Δ mice rescues dilated cardiomyopathy by providing tonic modulated trigger Ca2+. Methods and results Mouse and human models were tested. The muscle lim protein knockout mouse (MLPKO) is a murine model of dilated cardiomyopathy (DCM) and HFrEF. The …

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An Animal Interest Approach Method As A Gateway To A One Health Educated Pipeline, Meghan C. Wulster-Radcliffe, Sarah A. Reed, James N. Macleod, Rebekah B. Epps, J. Scott Radcliffe, Robert J. Coleman, Steven A. Zinn Oct 2025

An Animal Interest Approach Method As A Gateway To A One Health Educated Pipeline, Meghan C. Wulster-Radcliffe, Sarah A. Reed, James N. Macleod, Rebekah B. Epps, J. Scott Radcliffe, Robert J. Coleman, Steven A. Zinn

Animal and Food Sciences Faculty Publications

No abstract provided.

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Multiomics Analysis Of Skeletal Muscle Identifies Dysregulation Of Hypoxia-Induced Genes In Peripheral Artery Disease, Ahmed Ismaeel, Emma Fletcher, Evlampia Papoutsi, Nicholas T. Thomas, William T. Bohannon, Iraklis I. Pipinos, Yuan Wen, Dimitrios Miserlis, Panagiotis Koutakis Sep 2025

Multiomics Analysis Of Skeletal Muscle Identifies Dysregulation Of Hypoxia-Induced Genes In Peripheral Artery Disease, Ahmed Ismaeel, Emma Fletcher, Evlampia Papoutsi, Nicholas T. Thomas, William T. Bohannon, Iraklis I. Pipinos, Yuan Wen, Dimitrios Miserlis, Panagiotis Koutakis

Physiology Faculty Publications

BACKGROUND: Epigenetic modifications such as DNA methylation play a critical role in hypoxic cell programs. However, no previous studies have investigated the epigenetic regulation of gene expression in peripheral artery disease (PAD), a condition characterized by intermittent ischemia. Our study aims to examine how PAD affects the DNA methylome in skeletal muscle of patients with PAD with intermittent claudication or critical limb ischemia compared with non-PAD controls. METHODS: This was a cross-sectional study evaluating differences in the DNA methylome and transcriptome using reduced representation bisulfite sequencing, and small and bulk RNA sequencing, in skeletal muscle from non-PAD controls, intermittent claudication, …

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Scaling Symmetry Of The Hodgkin-Huxley Mathematical Model, Vladimir Valerievich Galanin Sep 2025

Scaling Symmetry Of The Hodgkin-Huxley Mathematical Model, Vladimir Valerievich Galanin

Progress in Scale Modeling, an International Journal

A computational method based on the application of a scaling transformation to the Hodgkin-Huxley mathematical model of the biological neuron and its generalizations to the case of various neural systems is proposed. The method makes it possible: 1) to obtain invariants of the scaling transformation of the Hodgkin-Huxley model; 2) to find self-similarity regions corresponding to the modes of neural activity; 3) to determine the conditions for the similarity of models of various types of biological neurons; 4) to reduce the order of the system of differential equations of the Hodgkin-Huxley model for neural systems with synchronous activity. The capabilities …

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