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Articles 9121 - 9150 of 18112
Full-Text Articles in Entire DC Network
Chronic Voluntary Alcohol Drinking Causes Anxiety-Like Behavior, Thiamine Deficiency, And Brain Damage Of Female Crossed High Alcohol Preferring Mice, Hong Xu, Hui Li, Dexiang Liu, Wen Wen, Mei Xu, Jacqueline A. Frank, Jing Chen, Haining Zhu, Nicholas J. Grahame, Jia Luo
Chronic Voluntary Alcohol Drinking Causes Anxiety-Like Behavior, Thiamine Deficiency, And Brain Damage Of Female Crossed High Alcohol Preferring Mice, Hong Xu, Hui Li, Dexiang Liu, Wen Wen, Mei Xu, Jacqueline A. Frank, Jing Chen, Haining Zhu, Nicholas J. Grahame, Jia Luo
Molecular and Cellular Biochemistry Faculty Publications
The central nervous system is vulnerable to chronic alcohol abuse, and alcohol dependence is a chronically relapsing disorder which causes a variety of physical and mental disorders. Appropriate animal models are important for investigating the underlying cellular and molecular mechanisms. The crossed High Alcohol Preferring mice prefer alcohol to water when given free access. In the present study, we used female cHAP mice as a model of chronic voluntary drinking to evaluate the effects of alcohol on neurobehavioral and neuropathological changes. The female cHAP mice had free-choice access to 10% ethanol and water, while control mice had access to water …
Changes In Both Trans- And Cis-Regulatory Elements Mediate Insecticide Resistance In A Lepidopteron Pest, Spodoptera Exigua, Bo Hu, He Huang, Songzhu Hu, Miaomiao Ren, Qi Wei, Xiangrui Tian, Mohammed Esmail Abdalla Elzaki, Chris Bass, Jianya Su, Subba Reddy Palli
Changes In Both Trans- And Cis-Regulatory Elements Mediate Insecticide Resistance In A Lepidopteron Pest, Spodoptera Exigua, Bo Hu, He Huang, Songzhu Hu, Miaomiao Ren, Qi Wei, Xiangrui Tian, Mohammed Esmail Abdalla Elzaki, Chris Bass, Jianya Su, Subba Reddy Palli
Entomology Faculty Publications
The evolution of insect resistance to insecticides is frequently associated with overexpression of one or more cytochrome P450 enzyme genes. Although overexpression of CYP450 genes is a well-known mechanism of insecticide resistance, the underlying regulatory mechanisms are poorly understood. Here we uncovered the mechanisms of overexpression of the P450 gene, CYP321A8 in a major pest insect, Spodoptera exigua that is resistant to multiple insecticides. CYP321A8 confers resistance to organophosphate (chlorpyrifos) and pyrethroid (cypermethrin and deltamethrin) insecticides in this insect. Constitutive upregulation of transcription factors CncC/Maf are partially responsible for upregulated expression of CYP321A8 in the resistant strain. Reporter gene assays …
The Correlation Between Plant Morphology And Dry Yield Of Elephantgrass, Xia Zhang, Hongru Gu, Chenglong Ding
The Correlation Between Plant Morphology And Dry Yield Of Elephantgrass, Xia Zhang, Hongru Gu, Chenglong Ding
IGC Proceedings (1977-2023)
No abstract provided.
Cytogenetical Studies On Hybrids Between S. Sudanense And S. Bicolor, Qiuwen Zhan, L. M. Zhu, J. J. Wu, W. Zhang, T. Z. Zhang
Cytogenetical Studies On Hybrids Between S. Sudanense And S. Bicolor, Qiuwen Zhan, L. M. Zhu, J. J. Wu, W. Zhang, T. Z. Zhang
IGC Proceedings (1977-2023)
No abstract provided.
Identification Of Chromosome And Fertility Of Bc1 Of Pentaploid Hybrid Between Elymus Canadensis And Elymus Dahuricus, Zhuo Yu, Yanhong Ma, Xiaolei Li, Zaozhe Li
Identification Of Chromosome And Fertility Of Bc1 Of Pentaploid Hybrid Between Elymus Canadensis And Elymus Dahuricus, Zhuo Yu, Yanhong Ma, Xiaolei Li, Zaozhe Li
IGC Proceedings (1977-2023)
No abstract provided.
Prospect On Conservation And Utilization Of Leucaena Leucocephala In Yunnan, Jun Yin, Long Jiang
Prospect On Conservation And Utilization Of Leucaena Leucocephala In Yunnan, Jun Yin, Long Jiang
IGC Proceedings (1977-2023)
No abstract provided.
Effect Of Different Explants On Callus Induction And Differentiation Of Perennial Ryegrass, Ru Yang, Qinghua Yuan
Effect Of Different Explants On Callus Induction And Differentiation Of Perennial Ryegrass, Ru Yang, Qinghua Yuan
IGC Proceedings (1977-2023)
No abstract provided.
International Paper And Interstate Water Pollution: A Two-Ton Problem In A One-Ton Regulatory Garbage Bag, Genie B. Whitesell
International Paper And Interstate Water Pollution: A Two-Ton Problem In A One-Ton Regulatory Garbage Bag, Genie B. Whitesell
Journal of Natural Resources & Environmental Law
No abstract provided.
Some Legal Solutions For Contemporary Problems Concerning Groundwater And Aquifers, Earl F. Murphy
Some Legal Solutions For Contemporary Problems Concerning Groundwater And Aquifers, Earl F. Murphy
Journal of Natural Resources & Environmental Law
No abstract provided.
Acid Rain: A Common Problem, A Joint Solution, Allan Gotlieb
Acid Rain: A Common Problem, A Joint Solution, Allan Gotlieb
Journal of Natural Resources & Environmental Law
No abstract provided.
Generation Of A Biobank From Two Adult Thoroughbred Stallions For The Functional Annotation Of Animal Genomes Initiative, Callum G. Donnelly, Rebecca R. Bellone, Erin N. Hales, Annee Nguyen, Scott A. Katzman, Ghislaine A. Dujovne, Kelly E. Knickelbein, Felipe Avila, Theodore S. Kalbfleisch, Elena Giulotto, Nicole B. Kingsley, Jocelyn Tanaka, Elizabeth Esdaile, Sichong Peng, Anna Dahlgren, Anna Fuller, Michael J. Mienaltowski, Terje Raudsepp, Verena K. Affolter, Jessica L. Petersen, Carrie J. Finno
Generation Of A Biobank From Two Adult Thoroughbred Stallions For The Functional Annotation Of Animal Genomes Initiative, Callum G. Donnelly, Rebecca R. Bellone, Erin N. Hales, Annee Nguyen, Scott A. Katzman, Ghislaine A. Dujovne, Kelly E. Knickelbein, Felipe Avila, Theodore S. Kalbfleisch, Elena Giulotto, Nicole B. Kingsley, Jocelyn Tanaka, Elizabeth Esdaile, Sichong Peng, Anna Dahlgren, Anna Fuller, Michael J. Mienaltowski, Terje Raudsepp, Verena K. Affolter, Jessica L. Petersen, Carrie J. Finno
Maxwell H. Gluck Equine Research Center Faculty Publications
Following the successful creation of a biobank from two adult Thoroughbred mares, this study aimed to recapitulate sample collection in two adult Thoroughbred stallions as part of the Functional Annotation of the Animal Genome (FAANG) initiative. Both stallions underwent thorough physical, lameness, neurologic, and ophthalmic (including electroretinography) examinations prior to humane euthanasia. Epididymal sperm was recovered from both stallions immediately postmortem and cryopreserved. Aseptically collected full thickness skin biopsies were used to isolate, culture and cryopreserve dermal fibroblasts. Serum, plasma, cerebrospinal fluid, urine, and gastrointestinal content from various locations were collected and cryopreserved. Under guidance of a board-certified veterinary anatomic …
Application Of Issr‐Pcr To Identification Two Different Ecotypes Of Lespedeza Hedysaroides, Xiufang Yang, Qizhong Sun
Application Of Issr‐Pcr To Identification Two Different Ecotypes Of Lespedeza Hedysaroides, Xiufang Yang, Qizhong Sun
IGC Proceedings (1977-2023)
No abstract provided.
Low‐Temperature Tolerance Related Cbf And Fructosyltrans Ferase Genes In Forage Grasses, H. Hisano, K. Tamura, M. Yoshida, A. Kanazawa, T. Yamada
Low‐Temperature Tolerance Related Cbf And Fructosyltrans Ferase Genes In Forage Grasses, H. Hisano, K. Tamura, M. Yoshida, A. Kanazawa, T. Yamada
IGC Proceedings (1977-2023)
No abstract provided.
Efficacy Of Bacteriophage Cocktail To Control E. Coli O157:H7 Contamination On Baby Spinach Leaves In The Presence Or Absence Of Organic Load, Badrinath Vengarai Jagannathan, Steven Kitchens, Paul Priyesh Vijayakumar, Stuart Price, Melissa Morgan
Efficacy Of Bacteriophage Cocktail To Control E. Coli O157:H7 Contamination On Baby Spinach Leaves In The Presence Or Absence Of Organic Load, Badrinath Vengarai Jagannathan, Steven Kitchens, Paul Priyesh Vijayakumar, Stuart Price, Melissa Morgan
Animal and Food Sciences Faculty Publications
Fruits and vegetables are high in nutrients that are essential for a healthy lifestyle. However, they also harbor an extensive array of microorganisms such as bacteria, which can be beneficial, neutral, or pathogenic. Foodborne pathogens can contaminate produce at any stage from the farm to the consumer’s table. Appropriate washing techniques using sanitizers can reduce the risk of pathogen contamination. Issues related to maintaining concentration, efficacy, and other problems have been a challenge for the food industry and, when left unresolved, have led to different outbreaks of foodborne illnesses. In this study, the efficacy of a lytic bacteriophage cocktail was …
Resolution Of The 'Sea Wars': Coastal Zone Management Act, Pamela L. Smillie
Resolution Of The 'Sea Wars': Coastal Zone Management Act, Pamela L. Smillie
Journal of Natural Resources & Environmental Law
No abstract provided.
Sitosterolemia: Twenty Years Of Discovery Of The Function Of Abcg5abcg8, Kori Williams, Allison Segard, Gregory A. Graf
Sitosterolemia: Twenty Years Of Discovery Of The Function Of Abcg5abcg8, Kori Williams, Allison Segard, Gregory A. Graf
Pharmaceutical Sciences Faculty Publications
Sitosterolemia is a lipid disorder characterized by the accumulation of dietary xenosterols in plasma and tissues caused by mutations in either ABCG5 or ABCG8. ABCG5 ABCG8 encodes a pair of ABC half transporters that form a heterodimer (G5G8), which then traffics to the surface of hepatocytes and enterocytes and promotes the secretion of cholesterol and xenosterols into the bile and the intestinal lumen. We review the literature from the initial description of the disease, the discovery of its genetic basis, current therapy, and what has been learned from animal, cellular, and molecular investigations of the transporter in the twenty …
Genome-Wide Association Meta-Analysis Identifies Pleiotropic Risk Loci For Aerodigestive Squamous Cell Cancers, Corina Lesseur, Aida Ferreiro-Iglesias, James D. Mckay, Yohan Bossé, Mattias Johansson, Valerie Gaborieau, Maria Teresa Landi, David C. Christiani, Neil C. Caporaso, Stig E. Bojesen, Christopher I. Amos, Sanjay Shete, Geoffrey Liu, Gadi Rennert, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardon, Chu Chen, Liloglou Triantafillos, John K. Field, Susanne Arnold
Genome-Wide Association Meta-Analysis Identifies Pleiotropic Risk Loci For Aerodigestive Squamous Cell Cancers, Corina Lesseur, Aida Ferreiro-Iglesias, James D. Mckay, Yohan Bossé, Mattias Johansson, Valerie Gaborieau, Maria Teresa Landi, David C. Christiani, Neil C. Caporaso, Stig E. Bojesen, Christopher I. Amos, Sanjay Shete, Geoffrey Liu, Gadi Rennert, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardon, Chu Chen, Liloglou Triantafillos, John K. Field, Susanne Arnold
Markey Cancer Center Faculty Publications
Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic susceptibility has not been performed. To identify novel and pleotropic SqCC risk variants, we performed a meta-analysis of GWAS data on lung SqCC (LuSqCC), oro/pharyngeal SqCC (OSqCC), laryngeal SqCC (LaSqCC) and esophageal SqCC (ESqCC) cancers, totaling 13,887 cases and 61,961 controls of European ancestry. We identified one novel genome-wide significant (Pmeta< 5x10-8) aerodigestive SqCC susceptibility loci in the 2q33.1 region (rs56321285, TMEM273). Additionally, three previously unknown …
Net Photosynthesis Rate And Transpiration Rate Of Algonquin With Different Growth Years, Lijun Xu, B. Wang, Q. Z. Sun
Net Photosynthesis Rate And Transpiration Rate Of Algonquin With Different Growth Years, Lijun Xu, B. Wang, Q. Z. Sun
IGC Proceedings (1977-2023)
No abstract provided.
Study On The Low Temperature Tolerance Of Zoysiagrass, Jiping Xuan, Jianxiu Liu, Zhifang Zhou, Xiaoli Cheng
Study On The Low Temperature Tolerance Of Zoysiagrass, Jiping Xuan, Jianxiu Liu, Zhifang Zhou, Xiaoli Cheng
IGC Proceedings (1977-2023)
No abstract provided.
Molecular Cloning And Characterization Of A Vacuolar H+‐Pyrophosphatase Gene From The Xerophyte Zygophyllum Xanthoxylum, Jiejun Xi, Guoqiang Wu, Aike Bao, Qian Wang, Suomin Wang
Molecular Cloning And Characterization Of A Vacuolar H+‐Pyrophosphatase Gene From The Xerophyte Zygophyllum Xanthoxylum, Jiejun Xi, Guoqiang Wu, Aike Bao, Qian Wang, Suomin Wang
IGC Proceedings (1977-2023)
No abstract provided.
Molecular Cloning And Characterization Of A Vacuolar Na+/H+ Antiporter Gene From The Succulent Xerophyte Zygophyllum Xanthoxylum, Guoqiang Wu, Jiejun Xi, Aike Bao, Suomin Wang
Molecular Cloning And Characterization Of A Vacuolar Na+/H+ Antiporter Gene From The Succulent Xerophyte Zygophyllum Xanthoxylum, Guoqiang Wu, Jiejun Xi, Aike Bao, Suomin Wang
IGC Proceedings (1977-2023)
No abstract provided.
Healthy Trees – Healthy People: A Model For Engaging Citizen Scientists In Exotic Pest Detection In Urban Parks, Heather Norman-Burgdolf, Lynne K. Rieske
Healthy Trees – Healthy People: A Model For Engaging Citizen Scientists In Exotic Pest Detection In Urban Parks, Heather Norman-Burgdolf, Lynne K. Rieske
Dietetics and Human Nutrition Faculty Publications
Healthy Trees – Healthy People (HT-HP) is an outreach and education program created to enlist and train participants in exotic pest detection while providing them with structured opportunities to connect with urban nature and increase their physical and emotional health. HT- HP creates infrastructure to increase engagement by the urban populace in the urban tree canopy. The program solicits participants to engage in an 8-week intervention designed to expand capacity to detect non-native insect pests and pathogens, while increasing physical activity, raising awareness of healthy lifestyle choices, and improving the health of participants. Program participants were trained in tree and …
Radiopharmaceutical Validation For Clinical Use, Charles A. Kunos, Rodney Howells, Aman Chauhan, Zin W. Myint, Mark E. Bernard, Riham H. El Khouli, Jacek Capala
Radiopharmaceutical Validation For Clinical Use, Charles A. Kunos, Rodney Howells, Aman Chauhan, Zin W. Myint, Mark E. Bernard, Riham H. El Khouli, Jacek Capala
Internal Medicine Faculty Publications
Radiopharmaceuticals are reemerging as attractive anticancer agents, but there are no universally adopted guidelines or standardized procedures for evaluating agent validity before early-phase trial implementation. To validate a radiopharmaceutical, it is desirous for the radiopharmaceutical to be specific, selective, and deliverable against tumors of a given, molecularly defined cancer for which it is intended to treat. In this article, we discuss four levels of evidence—target antigen immunohistochemistry, in vitro and in vivo preclinical experiments, animal biodistribution and dosimetry studies, and first-in-human microdose biodistribution studies—that might be used to justify oncology therapeutic radiopharmaceuticals in a drug-development sequence involving early-phase trials. We …
Analysis Of Root Morphological Variation Of Different Alfalfa Cultivars, Y. S. Wang, Linqing Yu, L. J. Zhang, C. Y. Zhang
Analysis Of Root Morphological Variation Of Different Alfalfa Cultivars, Y. S. Wang, Linqing Yu, L. J. Zhang, C. Y. Zhang
IGC Proceedings (1977-2023)
No abstract provided.
Issr Markers For Alfalfa Conferring Resistance To Common Leafspot, Yu Wang, Qinghua Yuan, Xianglin Li
Issr Markers For Alfalfa Conferring Resistance To Common Leafspot, Yu Wang, Qinghua Yuan, Xianglin Li
IGC Proceedings (1977-2023)
No abstract provided.
One Of The World Wide Elite Pasture‐Clovers, Yuedong Wang
One Of The World Wide Elite Pasture‐Clovers, Yuedong Wang
IGC Proceedings (1977-2023)
No abstract provided.
What Does Past Research Tell Us About Alfalfa Drying Rates?, Jordyn Bush
What Does Past Research Tell Us About Alfalfa Drying Rates?, Jordyn Bush
Kentucky Alfalfa and Stored Forage Conference
Today I’m going to give everyone a brief overview of a literature review I’ve been working on at the request of a local farmer. While writing this literature review, I looked at the factors that influence how quickly alfalfa dries down. I also read past research that has been conducted in an attempt to predict when hay will be dry or how long it will take to do so. The ultimate goal of this literature review was to determine the feasibility of creating some sort of hay drying prediction or forecasting system for Kentucky.
The Emerging Global Tobacco Treatment Workforce: Characteristics Of Tobacco Treatment Specialists Trained In Council-Accredited Training Programs From 2017 To 2019, Christine E. Sheffer, Abdulmohsen Al-Zalabani, Andrée Aubrey, Rasha Bader, Claribel Beltrez, Susan Bennett, Ellen Carl, Caroline Cranos, Audrey Darville, Jennifer Greyber, Maher Karam-Hage, Feras Hawari, Tresza Hutcheson, Victoria Hynes, Chris Kotsen, Frank Leone, Jamie Mcconaha, Heather Mccary, Crystal Meade, Cara Messick
The Emerging Global Tobacco Treatment Workforce: Characteristics Of Tobacco Treatment Specialists Trained In Council-Accredited Training Programs From 2017 To 2019, Christine E. Sheffer, Abdulmohsen Al-Zalabani, Andrée Aubrey, Rasha Bader, Claribel Beltrez, Susan Bennett, Ellen Carl, Caroline Cranos, Audrey Darville, Jennifer Greyber, Maher Karam-Hage, Feras Hawari, Tresza Hutcheson, Victoria Hynes, Chris Kotsen, Frank Leone, Jamie Mcconaha, Heather Mccary, Crystal Meade, Cara Messick
Nursing Faculty Publications
Tobacco use is projected to kill 1 billion people in the 21st century. Tobacco Use Disorder (TUD) is one of the most common substance use disorders in the world. Evidence-based treatment of TUD is effective, but treatment accessibility remains very low. A dearth of specially trained clinicians is a significant barrier to treatment accessibility, even within systems of care that implement brief intervention models. The treatment of TUD is becoming more complex and tailoring treatment to address new and traditional tobacco products is needed. The Council for Tobacco Treatment Training Programs (Council) is the accrediting body for Tobacco Treatment Specialist …
Increased Stress Tolerance In Transgenic Alfalfa Expressing At. Dreb1c Gene By Agrobacterium‐Mediated Genetic Transformation, Yongxin Wang, Ning Guan, Cong Li
Increased Stress Tolerance In Transgenic Alfalfa Expressing At. Dreb1c Gene By Agrobacterium‐Mediated Genetic Transformation, Yongxin Wang, Ning Guan, Cong Li
IGC Proceedings (1977-2023)
No abstract provided.
Genetic Diversity Analysis Of Ceratoides. (Tourn.) Gagnebin Germplasm Based On Rapd, Xuemin Wang, Hongwen Gao, Bing Han, Zan Wang, Jin Yi
Genetic Diversity Analysis Of Ceratoides. (Tourn.) Gagnebin Germplasm Based On Rapd, Xuemin Wang, Hongwen Gao, Bing Han, Zan Wang, Jin Yi
IGC Proceedings (1977-2023)
No abstract provided.