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Effect Of Exogenous Enzymes On Apparent Metabolizable Energy Value Of Barley In Swine And Broiler Chickens, Brian L. Bryson

Theses and Dissertations--Animal and Food Sciences

The objective of this thesis was to evaluate the effect of exogenous enzyme supplementation, phytase and xylanase-glucanase, on AME value of barley in poultry and swine. In the first study, 280 broilers were assigned 1 of 8 treatments. Barley inclusion in the diet resulted in decreased (P < 0.05) performance. There was a treatment × phytase × xylanase-glucanase interaction for dry matter retention with birds fed the corn-SBM-barley diet supplemented with phytase and xylanase-glucanase having higher (P < 0.05) DM retention compared to birds fed corn-SBM-based diet with only xylanase-glucanase supplementation. AME and AMEn of corn-SBM-based diets were greater (P < 0.05) than the corn-SBM-barley-based diets. Energy metabolizability and AMEn of barley significantly increased with xylanase-glucanase supplementation. In the second study, 24 pigs (12 pigs/phase) were assigned to 1 of 4 treatments with xylanase-glucanase and phytase. After a 7-d adaption period, urine and feces were quantitatively collected for 5 d. DE of the barley-based diet supplemented with xylanase-glucanase (3,578 kcal/kg) and phytase and xylanase-glucanase in combination (3,617 kcal/kg) were significantly different. Compared to control diets, exogenous enzymes either significantly improved or had a tendency to improve AME and AMEn value of barley in broilers, but not in growing pigs.

Compost Bedded Pack Dairy Housing: Animal Performance And Well-Being And Economic Viability In A Pasture-Based System, Betty Kawonga

Theses and Dissertations--Animal and Food Sciences

Improving housing for dairy cattle is of interest because hoof and udder health, which are associated with the housing environment, are important economic and welfare issues. The objectives were: 1) to assess the influence of housing––conventional cubicle (CCD) vs compost bedded pack (CBP),––and management (grazing vs semi-grazing) on the performance and welfare in dairy cows 2) describe the performance of the CBP under a grazing or semi-grazing system, and 3) to assess viability of CBP housing in a pasture-based system. This study mixes three research approaches, an analysis of existing and secondary data; an experiment, and a case-study. If taken …

Unending Mazes: Gendered Inequalities, Drug Use, And State Interventions In Rural Appalachia, Lesly-Marie Buer

Theses and Dissertations--Anthropology

Prescription opioids are associated with rising rates of overdose deaths and hepatitis C and HIV infection in the US, including in rural Central Appalachia. Yet there is a dearth of published ethnographic research examining rural opioid use. The aim of this dissertation is to document the gendered inequalities that situate women’s encounters with substance abuse treatment as well as additional state interventions targeted at women who use drugs. These results are based on ethnographic fieldwork completed from 2013 to 2016 and centered around one county seat in rural Central Appalachia. Data are ascertained through semi-structured interviews with women who have …

Disturbance Of Redox Homeostasis In Down Syndrome: Role Of Iron Dysmetabolism, Eugenio Barone, Andrea Arena, Elizabeth Head, D. Allan Butterfield, Marzia Perluigi

Sanders-Brown Center on Aging Faculty Publications

Down syndrome (DS) is the most common genetic form of intellectual disability that leads in the majority of cases to development of early-onset Alzheimer-like dementia (AD). The neuropathology of DS has several common features with AD including alteration of redox homeostasis, mitochondrial deficits, and inflammation among others. Interestingly, some of the genes encoded by chromosome 21 are responsible of increased oxidative stress (OS) conditions that are further exacerbated by decreased antioxidant defense. Previous studies from our groups showed that accumulation of oxidative damage is an early event in DS neurodegeneration and that oxidative modifications of selected proteins affects the integrity …

The Lion, The Bat & The Thermostat: Metaphors On Consciousness, Brian L. Frye

Law Faculty Scholarly Articles

No abstract provided.

The Sharpest Tool In The Toolbox: Visual Legal Rhetoric, Michael D. Murray

Law Faculty Scholarly Articles

Visual briefs and other forms of visual rhetoric in legal communication may eventually become the norm in legal practice because of the enormous communicative and rhetorical power of visual media. I have discussed the uses of visual legal rhetoric and the ensuing ethical and professional considerations elsewhere. Here, I will focus on providing instruction to law students and lawyers regarding proper and effective usage of visual legal rhetoric.

Environmental Exposure To Atrazine And Birth Defects: An Ecological Study In Kentucky, 2005-2014, Maria Dimitrios Politis

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Atrazine is one of the most widely used pesticides in the United States. Studies have shown that pesticides, in particular herbicides such as atrazine, may be associated with birth defects. The purpose of this study is to evaluate the association between potential environmental exposures to atrazine in water systems and prevalence rates of birth defects for the state of Kentucky. An ecological study using the Kentucky Birth Defects Registry Surveillance and the Kentucky Geological Survey databases from 2005 to 2014 was conducted. Poisson regression was used to estimate crude and adjusted rate ratios of the association between agricultural exposure metrics …

Building Teacher Efficacy: Challenges Of Creating Communities Of Practice Among New Teachers And Veteran Teachers In A Toxic Work Environment, J Lail

Theses and Dissertations--Educational Leadership Studies

Recently, changes in graduation requirements in some states have made it more important than ever for students to be literate in all content areas. State assessments not only measure student academic ability, but they are a necessary component of graduation from high school. After completing required courses, students are expected to take assessments covering the content of those courses. In order to safely meet the graduation requirement, students must score at least 3 points per assessment on a 5-point scale. This has proven difficult for over 50% of students expecting to graduate.

Students at Midwestern-American High School (MAHS) have been …

The Effect Of Sleep Quantity And Quality On Direct Current Potential In Collegiate American Football Players, Erik D. Korem

Theses and Dissertations--Kinesiology and Health Promotion

Direct current (DC) potential is an objective measure of the functional state of the human organism. It is a sensitive and accurate indicator of short- and long-term adaptations to stress, adaptive capacities, and it is an important marker of athlete readiness. Sleep is posited to be the most efficacious strategy for improving recovery to enhance sport performance, and adequate sleep is considered vital to normal psycho-physiological function. Thus, optimal sleep may enhance the functional state, in turn enhancing an athlete’s adaptability to training stress. However, little is known about the relationship between sleep and DC potential. Therefore, the purpose of …

Effects Of High Fat Exposure On Skeletal Muscle Autophagy And Endoplasmic Reticulum Stress, Adrienne Rose Herrenbruck

Theses and Dissertations--Kinesiology and Health Promotion

Autophagy is a major degradation mechanism, responsible for clearing damaged and dysfunctional organelles, including the endoplasmic reticulum, a structure essential for protein synthesis and myocellular hypertrophy. Alterations in autophagy throughout various tissues of the body have been linked to various negative side effects such as decreased myocellular hypertrophy and insulin resistance. High fat diets lead to changes (both increases and decreases) in autophagy in various tissues throughout the body in a tissue-specific manner.

Skeletal muscle autophagy is decreased in myotubes cultured from obese women, however the mechanism by which this occurs is unknown. As the largest organ system in the …

Community College Campuses And Sexual Minorities: The Experience Of Lgbtq Students At Community Colleges, Baron Guy Wolf

Theses and Dissertations--Educational Policy Studies and Evaluation

The purpose of this study was to examine national survey data from across the United States for respondents from two-year community colleges. Historically little empirical evidence exists in the literature about this population of students who identity as sexual minorities. The study begins with a historical overview of the LGBTQ rights movement. This provides a baseline for why studies including this invisible minority group are important and especially timely for two-year college campuses. Literature is barrowed from four-year college and university studies. Data were analyzed using the Rasch Partial Credit model. This analysis included testing for data-fit to the model, …

Towards Better Outcomes For Families With Transition-Age Youth Or Young Adults With Asd: A Mixed Methods Study From A Parent’S Perspective, Wing Hang Wong

Theses and Dissertations--Educational, School, and Counseling Psychology

The after-high-school outcomes for individuals with autism spectrum disorder (ASD) and their families are less than desirable. The current study employed an exploratory sequential mixed methods design in order to enhance understanding of the family adaptation process during transition. First, a qualitative study was conducted in order to understand the stressors, external and internal support, coping strategies, and family adaptation outcomes during transition, from a parent’s perspective, using the ABCX model. Thirteen parents of adolescents and young adults with ASD were interviewed. These parents reported a continually high level of stress due to normative strains and ASD-related demands. They clearly …

Risk And Protective Factors For Sexual Desire Among Women With Children And Their Romantic Partners, Christine E. Leistner

Theses and Dissertations--Education Sciences

Romantic couples with children struggle to balance the needs of their romantic relationships with the responsibilities of parenting and mothers report difficulty viewing themselves as sexual beings after having children. Understanding the risk and protective factors for sexual and relational outcomes for couples with children or those that may have children in the future may provide insight into the dynamics of these couples and the ways in which parents can preserve relational health over time. The current study utilized Basson’s Model of Sexual Response (2000) as a conceptual theoretical framework and the Actor Partner Interdependence Model (APIM; Kenny et al., …

Multimodal Noncontact Diffuse Optical Reflectance Imaging Of Blood Flow And Fluorescence Contrasts, Daniel Irwin

Theses and Dissertations--Biomedical Engineering

In this study we design a succession of three increasingly adept diffuse optical devices towards the simultaneous 3D imaging of blood flow and fluorescence contrasts in relatively deep tissues. These metrics together can provide future insights into the relationship between blood flow distributions and fluorescent or fluorescently tagged agents. A noncontact diffuse correlation tomography (ncDCT) device was firstly developed to recover flow by mechanically scanning a lens-based apparatus across the sample. The novel flow reconstruction technique and measuring boundary curvature were advanced in tandem. The establishment of CCD camera detection with a high sampling density and flow recovery by speckle …

Sleep And Thermoregulation: A Study Of The Effect Of Ambient Temperature Manipulation On Mouse Sleep Architecture, Asma'a A. Ajwad

Theses and Dissertations--Biomedical Engineering

Good quality sleep is essential for mental and physical health. Inadequate sleep impacts memory consolidation, learning and cognition, immune function, autonomic regulation, physical performance, and other vital functions. In many neurological disorders that are associated with sleep problems such as epilepsy and Alzheimer’s disease, changes in brain circuitry affect sleep-wake regulation mechanisms; this is reflected in anomalous sleep-wake architecture and usually accompanied by poor sleep depth. Thus, over many years, many approaches have been tried in humans and animal models with the goal of improving sleep quality. Unfortunately, each of those approaches comes with limitations or side effects. Thus, there …

Preferential Pathways For Vapor Intrusion: Site Screening And Field Sampling Of Sewers To Assess Inhalation Exposure Risks, Evan James Willett

Theses and Dissertations--Civil Engineering

Hazardous waste sites and aging wastewater infrastructure are common in the United States. There are hundreds of thousands of contaminated sites and more than a million miles of sewer pipes. Populations living close to hazardous waste sites often suffer from increased risk of adverse health effects due to exposure to contaminated environmental media. Vapor intrusion is one process by which nearby populations can be exposed to volatile organic compounds (VOCs). Aging wastewater infrastructure is important for vapor intrusion site assessments because sewer pipes can serve as preferential vapor transport pathways. Near contaminated sites, pipe deterioration allows migration of contaminants into …

Numerical Modeling And Isotope Tracers To Investigate Karst Biogeochemistry And Transport Processes, Admin Husic

Theses and Dissertations--Civil Engineering

This dissertation investigated the physical and biogeochemical processes affecting the source, fate, and transport of sediment, carbon, and nitrogen within a highly-coupled fluviokarst system. Elemental and isotopic datasets were collected at surface and subsurface locations for both dissolved and particulate contaminant phases, new methodology regarding data collection was presented to the karst research community, an in-cave sediment transport model coupling physical transport with elemental and isotopic mass balances of carbon and nitrogen was formulated, pathway and process control on nitrate leaching from agricultural karst watersheds was assessed, and nitrate mobilization and fractionation were modeled using high frequency storm sampling and …

Modeling And Mapping Location-Dependent Human Appearance, Zachary Bessinger

Theses and Dissertations--Computer Science

Human appearance is highly variable and depends on individual preferences, such as fashion, facial expression, and makeup. These preferences depend on many factors including a person's sense of style, what they are doing, and the weather. These factors, in turn, are dependent upon geographic location and time. In our work, we build computational models to learn the relationship between human appearance, geographic location, and time. The primary contributions are a framework for collecting and processing geotagged imagery of people, a large dataset collected by our framework, and several generative and discriminative models that use our dataset to learn the relationship …

Jak/Stat Signaling Regulates Gametogenesis And Age-Related Reproductive Maintenance, Michelle Suzanne Giedt

Theses and Dissertations--Biology

Cell signaling is central to integration of internal and external cues that regulate development and homeostasis. Most development is thought of as pre-adult, but limited developmental processes occur in adults. Gametogenesis incorporates elements of both these facets, with a distinct developmental plan for gamete synthesis which is regulated by integration of homeostatic inputs such as nutrient status, and environmental cues. Signaling pathways integrate and transduce information from these cues to evoke a response. A decline in homeostasis and subsequent cues occurs over time, in the case of reproductive tissues leading to a progressive loss of fertility. The Janus Kinase and …

“Beyond Sisterhood There Is Still Racism, Colonialism And Imperialism!” Negotiating Gender, Ethnicity And Power In Madagascar Mangrove Conservation, Manon Lefèvre

Theses and Dissertations--Geography

Understanding women’s experiences of mangrove forest conservation in the Global South is important because mangrove forests are a crucial defense against climate change, and are also increasingly the targets of global climate change policies. The intervention of postcolonial feminist theory combined with feminist political ecology has the potential to bring forward women’s seldom-heard experiences of climate change in these valuable ecosystems. This work supports previous feminist political ecology scholarship focused on understanding women’s complicated relationships to the environment and the gendered effects of climate change policies, while challenging dominant conservation discourse around women as a monolithic group. This thesis focuses …

Moving Experiences: Women And Mobility In Late Nineteenth And Early Twentieth-Century American Literature, Amy Simpson Birk

Theses and Dissertations--English

This project recovers and revises late nineteenth and early twentieth-century narratives of mobility which invoke female protagonists who move from stifling, patriarchal domestic settings in the rural and suburban United States to the more symbolically emancipated settings of New York City and even Europe to reveal both the limitations and possibilities for women’s lives in the United States at the turn of the twentieth century. By challenging popular American fiction’s preoccupation with urban white slavery myths and the lingering proscriptive standards for women’s behavior of the Victorian era, the Introduction argues the selected works of this dissertation mark a significant, …