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Patterns Of Inheritance Of Acylsugar Acyl Groups In Selected Interspecific Hybrids Of Genus Nicotiana, Antoaneta B. Mihaylova-Kroumova, Ivan Artiouchine, Victor D. Korenkov, George J. Wagner

Kentucky Tobacco Research and Development Center Faculty Publications

Glandular trichomes on the surface of Solanaceae species produce acyl sugars that are species-, and cultivar-specific. Acyl sugars are known to possess insecticidal, antibiotic, and hormone-like properties, and as such have great potential as a class of naturally occurring pesticides and antibiotics. The objective of this work was to analyze the acyl composition of acyl sugars in the leaf trichome exudate from selected Nicotiana species and to follow the inheritance of acyl content in their hybrids. Trichome exudates were collected, and the acyl profiles of acyl sugars were identified via GC–MS. The variations in acyl group inheritance in the hybrids …

Palbociclib Treatment Alters Nucleotide Biosynthesis And Glutamine Dependency In A549 Cells, Lindsey R. Conroy, Pawel Lorkiewicz, Liqing He, Xinmin Yin, Xiang Zhang, Shesh N. Rai, Brian F. Clem

Neuroscience Faculty Publications

Background

Aberrant activity of cell cycle proteins is one of the key somatic events in non-small cell lung cancer (NSCLC) pathogenesis. In most NSCLC cases, the retinoblastoma protein tumor suppressor (RB) becomes inactivated via constitutive phosphorylation by cyclin dependent kinase (CDK) 4/6, leading to uncontrolled cell proliferation. Palbociclib, a small molecule inhibitor of CDK4/6, has shown anti-tumor activity in vitro and in vivo, with recent studies demonstrating a functional role for palbociclib in reprogramming cellular metabolism. While palbociclib has shown efficacy in preclinical models of NSCLC, the metabolic consequences of CDK4/6 inhibition in this context are largely unknown.

Methods

In …

Which Vegetation Sampling Approach Is More Efficient For A Rangeland Inventory?, Gh. Ghanbarian, M. Mesdaghi, H. Barani, M. Azimmohseni

IGC Proceedings (1977-2023)

No abstract provided.

Presentation Of Diversity, Life Forms And Chorology Of Plant Species In Rangelands Of Jahrom, Gh. Ghanbarian, E. Jafari, A. Hatami, M. Tayebi Khorrami

IGC Proceedings (1977-2023)

No abstract provided.

Analysis Of C‐Banding And Karyotype Of Chromosome Of Two Galega Species, Hongwen Gao, Xinyu Zhang, Zan Wang

IGC Proceedings (1977-2023)

No abstract provided.

Obstacles Of Determining Compensation In Grassland Ecological Values, Zhiyi Gai, Xiufang Gao

IGC Proceedings (1977-2023)

No abstract provided.

Application Of Analytical Hierarchy Process (Ahp) In Priority Classification Of Utilization Measurement Methods In Agropyrun Trichophrum Stands In Upland Grasslands Of Iran, Fazel Amiri

IGC Proceedings (1977-2023)

No abstract provided.

Assessment Of Important Environmental Factors Affecting Agropyron Trichophrum Establishment By Using An Ordination Method, Fazel Amiri, M. R. Chaichi, T. Tabatabai

IGC Proceedings (1977-2023)

No abstract provided.

Inter‐Annual Dynamics Of Grassland Yields And Assessment Of Herbage Supply In The Headwater Region Of Three Rivers Over 18 Years, Jiangwen Fan, Junbang Wang, Zhouqi Chen, Huaping Zhong, Quanqin Shao, Jiyuan Liu, Wenyan Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Dynamics Of Leymus Chinensis And Hierochloe Glabrain Grassland Plantings Within The Songnen Plains Of China, Guangzhi Fan, Yunfei Yang

IGC Proceedings (1977-2023)

No abstract provided.

Testing The Neutral Theory Of Plant Communities In Subalpine Meadow, Xiaoguang Du, Shurong Zhou

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Grazing On Reproductive Characteristics Of Stipabreviflora In Desert Steppe, Lixia Du, Qingfeng Li

IGC Proceedings (1977-2023)

No abstract provided.

Long‐Term Cattle Grazing Affected Specific Leaf Area And Its Components In Two Range Plant Species, Xuejun Dong, Paul Nyren, Bob Patton, Brian Kreft, Anne Nyren

IGC Proceedings (1977-2023)

No abstract provided.

Photosynthesis And Soil Respiration From A Mixed‐Grass Prairie: Effects Of Grazing And Drought, Xuejun Dong, Paul Nyren, Bob Patton, Guojie Wang, Brian Kreft, Anne Nyren, Ryan Limb, Don Kirby, Larry Cihacek

IGC Proceedings (1977-2023)

No abstract provided.

Effect Of Salt Stress On The Tall Wheatgrass At The Stage Of Seedling, Kuanhu Dong, Yanqing Liu

IGC Proceedings (1977-2023)

No abstract provided.

Efficacy Of Stem Cell Allograft In Maxillary Sinus Bone Regeneration: A Randomized Controlled Clinical And Blinded Histomorphometric Study, Josh Whitt, Mohanad Al-Sabbagh, Dolph R. Dawson Iii, Ehab Shehata, Moly Housley-Smith, Alejandro G. Villasante Tezanos, Ahmad Kutkut

Oral Health Practice Faculty Publications

Purpose: This study aimed to evaluate the quality and quantity of newly generated bone in the maxillary sinus grafted with stem cell-based allograft material.

Methods: This study was a single site, prospective, blinded, randomized, and controlled clinical trial. Eleven subjects with 18 edentulous posterior maxillary sites requiring sinus augmentation for delayed implant placement using a lateral window approach were enrolled. At the time of sinus augmentation, test sinus was grafted with stem cell-based allograft (Osteocel Plus; NuVasive Therapeutics), while the control sinus was grafted with conventional cortico-cancellous allograft (alloOss; ACE Surgical). Cone beam computer tomography (CBCT) scan was taken before …

Electrochemical Evaluation Of A Multi-Site Clinical Depth Recording Electrode For Monitoring Cerebral Tissue Oxygen, Ana Ledo, Eliana Fernandes, Jorge E. Quintero, Greg A. Gerhardt, Rui M. Barbosa

Neurosurgery Faculty Publications

The intracranial measurement of local cerebral tissue oxygen levels—PbtO₂—has become a useful tool for the critical care unit to investigate severe trauma and ischemia injury in patients. Our preliminary work in animal models supports the hypothesis that multi-site depth electrode recording of PbtO₂ may give surgeons and critical care providers needed information about brain viability and the capacity for better recovery. Here, we present a surface morphology characterization and an electrochemical evaluation of the analytical properties toward oxygen detection of an FDA-approved, commercially available, clinical grade depth recording electrode comprising 12 Pt recording contacts. We found that …

Diachronic Analysis Of Vegetation In The Sylvopastoral Zone (Senegal): What Lesson To Learn From?, A. T. Diop, A. Diouf, A. Wane

IGC Proceedings (1977-2023)

No abstract provided.

The Effect Of Hay Covered On Soil Evaporation, Xiangxin Cui, Yong Gao, Xingyuan Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Experimental Study On Stipa Bungeana Grassland Of Enclosed, Cutting And Grazing Succession For 26 Years Semi‐Arid Region Of Northwest, J. M. Cheng, L. P. Qiu, Q. Wang, J. Cheng, X. N. Jia

IGC Proceedings (1977-2023)

No abstract provided.

Variation Of Pod Activity In Roots Of Different Fall Dormancy Alfalfa Under The Autumn Cutting, Libo Chen, Lei Liu, Zhiyong Li, Meizhen Wang

IGC Proceedings (1977-2023)

No abstract provided.

Grazing Behaviors Of Goats And Sheep In Winter And Spring In A Desert Steppe, H. J. Chen, Mingjiu Wang, Y. M. Shan, Zh. Y. Wu, Zh. Q. Li

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Different Enzyme Combination And Dissociation‐Time On The Protoplast Isolation Of Alfalfa, Aiping Chen, Yupeng Luo, Run Yan, Bo Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Viral Membrane Fusion And The Transmembrane Domain, Chelsea T. Barrett, Rebecca Ellis Dutch

Molecular and Cellular Biochemistry Faculty Publications

Initiation of host cell infection by an enveloped virus requires a viral-to-host cell membrane fusion event. This event is mediated by at least one viral transmembrane glycoprotein, termed the fusion protein, which is a key therapeutic target. Viral fusion proteins have been studied for decades, and numerous critical insights into their function have been elucidated. However, the transmembrane region remains one of the most poorly understood facets of these proteins. In the past ten years, the field has made significant advances in understanding the role of the membrane-spanning region of viral fusion proteins. We summarize developments made in the past …

Analysis Of Photosynthetic Characteristics Of Heteropogon Contortusin Arid‐Hot Valley Areas Of Jinsha River, Yufen Bi, X. L. Ma, T. Sun

IGC Proceedings (1977-2023)

No abstract provided.

The Caloric Values Of Main Plant Species And Functional Groups In The Steppe Communities Of Xilin River Basin, Yajing Bao, Zhenghai Li

IGC Proceedings (1977-2023)

No abstract provided.

Plant Energy Functional Groups And Their Coupling Relationship With The Functional Degradation Of Steppe Ecosystem, Yajing Bao, Zhenghai Li, Xingguo Han

IGC Proceedings (1977-2023)

No abstract provided.

Profile Of Water Uptake In Winterfat During Seed Germination, Ruojing Wang, Yuguang Bai, Edward J. Kendall, Karen Tanino

IGC Proceedings (1977-2023)

No abstract provided.

Spermine Synthase And Myc Cooperate To Maintain Colorectal Cancer Cell Survival By Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, Qing-Bai She

Markey Cancer Center Faculty Publications

Dysregulation of polyamine metabolism has been linked to the development of colorectal cancer (CRC), but the underlying mechanism is incompletely characterized. Here, we report that spermine synthase (SMS), a polyamine biosynthetic enzyme, is overexpressed in CRC. Targeted disruption of SMS in CRC cells results in spermidine accumulation, which inhibits FOXO3a acetylation and allows subsequent translocation to the nucleus to transcriptionally induce expression of the proapoptotic protein Bim. However, this induction is blunted by MYC-driven expression of miR-19a and miR-19b that repress Bim production. Pharmacological or genetic inhibition of MYC activity in SMS-depleted CRC cells dramatically induces Bim expression and apoptosis …

Adaptation Benefit Two Grass Coexisting In Meadow Steppe Of Northeast China, Lei Ba, Wei Xu, Deli Wang

IGC Proceedings (1977-2023)

No abstract provided.