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Moving Towards Wellness: How Exercise Can Ease Depression And Anxiety In Young Adults, Morgan Hartze Mar 2026

Moving Towards Wellness: How Exercise Can Ease Depression And Anxiety In Young Adults, Morgan Hartze

Psychology Student Publications

Depression and anxiety are among the most common mental health concerns affecting young adults, impacting mood, motivation, and daily functioning. While therapy and medication can be effective, many young adults continue to experience symptoms, highlighting the need for additional strategies. Research suggests that regular physical activity is an accessible, cost-effective way to improve mental health. Moving your body boosts the “feel good” chemicals, such as serotonin and dopamine, while reducing stress hormones, such as cortisol. Physical activity also provides a healthy distraction from negative thoughts and helps establish routines that support well-being. Even brief amounts of moderate exercise, such as …


Couples Neutrality, Marriage Neutrality, And Two-Earner Deductions, Daniel Shaviro Mar 2026

Couples Neutrality, Marriage Neutrality, And Two-Earner Deductions, Daniel Shaviro

Loyola of Los Angeles Law Review

Tax policy discussions of how to tax married couples, as compared to singles, often focus on the by now much-criticized norms of “marriage neutrality” and “couples neutrality.” While these norms are largely unpersuasive, they do offer a useful analytic starting point, because of both (a) how they relate to more validly expressed concerns, and (b) the significance of the empirical reasons why they generally do not hold.

In evaluating the proper relative tax treatment of different married couples, one of the most important factors that the federal income tax law fails to recognize is the difference between one-earner and two-earner …


Motive To Kill: The Link Between Childhood Trauma And Homicide, Natalie L. Scholz Mar 2026

Motive To Kill: The Link Between Childhood Trauma And Homicide, Natalie L. Scholz

Psychology Student Publications

What motivates some individuals to commit homicide and what role does childhood trauma play in increasing that risk? Psychology and neuroscience suggest that when a child experiences traumatic events it can change how they handle stress, emotional control, and how their brain develops. All these factors can lead to them acting out in more violent ways. The Adverse Childhood Experiences study shows that traumatic events during one’s childhood can have a negative effect on their mental wellbeing later in life making them more prone to act out aggressively and possibly having more criminal involvement. Exposure to trauma has been linked …


Approved Programs 3-31-26, Angela Brock Mar 2026

Approved Programs 3-31-26, Angela Brock

Programs Committee (PC)

No abstract provided.


Program Agenda 3-31-26, Angela Brock Mar 2026

Program Agenda 3-31-26, Angela Brock

Programs Committee (PC)

No abstract provided.


Sexual Behavior Transitions Among Transgender Women In Indonesia: Insights From Palembang City And Banyuasin District, South Sumatra, Rico Januar Sitorus, Misnaniarti Misnaniarti, Novrikasari Novrikasari, Beka Purnama, Merry Natalia Panjaitan Mar 2026

Sexual Behavior Transitions Among Transgender Women In Indonesia: Insights From Palembang City And Banyuasin District, South Sumatra, Rico Januar Sitorus, Misnaniarti Misnaniarti, Novrikasari Novrikasari, Beka Purnama, Merry Natalia Panjaitan

Media Kesehatan Masyarakat Indonesia

Despite ongoing HIV prevention efforts, risky sexual behavior among transgender women remains a major public health concern in Indonesia. However, limited evidence is available regarding the determinants of sexual behavior among transgender women. This study aimed to analyze the main determinants influencing sexual behavior among transgender women in Palembang City and Banyuasin Regency, South Sumatra, Indonesia. A quantitative ap-proach with a cross-sectional design was employed, involving 233 transgender women. Sampling was conducted using the Time Loca-tion Sampling (TLS) method in collaboration with Warna Sriwijaya Foundation between June and October 2025. Data were collected through a structured and validated questionnaire covering …


Cognitive Drunkenness: Sleep Deprivation And Cognition In College Students, Alexandra Pavek Mar 2026

Cognitive Drunkenness: Sleep Deprivation And Cognition In College Students, Alexandra Pavek

Psychology Student Publications

Sleep deprivation is a common occurrence among college students. The purpose of the paper is to shed light on the sources of sleep loss in college students, the cognitive consequences, and the comparison to alcohol-related impairment.


The Science Of Attachment: How Early Bonds Shape Who We Become, Rani Patel Mar 2026

The Science Of Attachment: How Early Bonds Shape Who We Become, Rani Patel

Psychology Student Publications

Attachments theories suggest the answer begins in infancy. Originally developed by John Bowlby and later supported by the “Strange Situation” attachment research conducted by Mary Ainsworth, attachment science shows that the quality of early interactions with caregivers influence how children develop trust, seek support, and manage emotions. Through years of empirical research psychologists have identified four main attachment styles, secure, anxious, avoidant, and disorganized, later connected to relationship patterns. Modern research also highlights that attachment patterns are not permanent, supportive experiences later in life can promote growth and change.


Automatic Classification Of Orange Fruit Diseases Using Multilayer Deep Features And Traditional Machine Learning Classifiers, Maha A. Rajab, Faris Ali Jasim Shaban, Kadhim Mahdi Hashim Mar 2026

Automatic Classification Of Orange Fruit Diseases Using Multilayer Deep Features And Traditional Machine Learning Classifiers, Maha A. Rajab, Faris Ali Jasim Shaban, Kadhim Mahdi Hashim

Mesopotamian Journal of Big Data

Citrus diseases are the main issue for agricultural productivity, which cause a reduction in yield and quality, thus causing economic loss; also, we see that traditional methods of diagnosis, which are very subjective and prone to error, and thus we need to suggest accurate automated detection systems. In this study, we present a hybrid model that integrates conventional machine learning with deep learning models. We used the Gray Level Co-occurrence Matrix (GLCM) for feature extraction, which is classified via machine learning algorithms like k-Nearest Neighbors (KNN), Decision Tree (DT), Linear Discriminant Analysis (LDA), and Random Forest (RF). At the same …


Experiential Avoidance And Acceptance-Based Therapy (Abbt), Addison Jo Quern Mar 2026

Experiential Avoidance And Acceptance-Based Therapy (Abbt), Addison Jo Quern

Psychology Student Publications

Anxiety is an incredibly common mental health concern that impacts individuals globally. Avoidance is a main feature that maintains the symptoms of anxiety but does not allow the individual to experience the distressing scenario, thus reaffirming that discomfort. This attempt to control or avoid anxiety can make the symptoms worse. Research demonstrates that avoidance can perpetuate anxiety, and stress can increase avoidance. Acceptance-based therapy (ABBT) is used to target avoidance behaviors to lessen the overall symptoms of anxiety. ABBT is a third wave of therapy that helps clients focus on the relationship they have with their thoughts and feelings, instead …


Present And Future Effects Of Parental Discipline - What's The Best Way To Parent?, Erica Morrison Mar 2026

Present And Future Effects Of Parental Discipline - What's The Best Way To Parent?, Erica Morrison

Psychology Student Publications

Different parenting styles can have different and long lasting effects on one's children. How we parent can largely shape who your child will become.


The Predictive Ability Of Child Characteristics And Parenting Factors On Four Developmental Domains In Toddlers, Melly Latifah, Dwi Hastuti, Neti Hernawati, Reisi Nurdiani, Raihan Ainun Hasanah Mar 2026

The Predictive Ability Of Child Characteristics And Parenting Factors On Four Developmental Domains In Toddlers, Melly Latifah, Dwi Hastuti, Neti Hernawati, Reisi Nurdiani, Raihan Ainun Hasanah

Jurnal Keperawatan Indonesia

Stunting is a chronic condition that has a significant impact on child development. This phenomenon is primarily caused by prolonged nutritional deficiency, especially during the first 1,000 days of life. In addition, as family factors also play a crucial role in children’s development, this study aims to analyze the influence of child and family characteristics, mother–child attachment, parenting practices, and the nutritional status of children (stunted/non-stunted) on children’s gross motor, fine motor, language, and personal–social skills. This study used a quantitative design with an explanatory approach involving 202 mother–child pairs with children aged 12–36 months. The findings show that healthcare …


Determining Factors Leading To Sobriety In Native American Graduates Of A Joint-Jurisdictional Court Program, Ryan Fisher Mar 2026

Determining Factors Leading To Sobriety In Native American Graduates Of A Joint-Jurisdictional Court Program, Ryan Fisher

Walden Dissertations and Doctoral Studies

The issue of driving under the influence (DUI) is a continuous problem in rural communities, especial those in Indian Country. Alcohol use and abuse has long been a health concern for these communities contributing to higher mortality rates and increased incarceration rates for American Indian / Alaskan Native (AIAN) populations. Wellness courts, using the problem-solving court model, have been successful in helping DUI offenders achieve sobriety and wellness. While the model has been successful, there remains a lack of qualitative research into why participants find success in these programs; especially marginalized populations such as AIAN. This phenomenological qualitative study was …


Free Versus In Situ Right Internal Mammary Artery As A Conduit In Coronary Artery Bypass Surgery: A Meta-Analysis, Yuta Kikuchi, Tomoki Sakata, Tomonari Shimoda, Shinichi Fukuhara, Junichi Shimamura, Makoto Hibino, Tsuyoshi Kaneko, Hiroo Takayama, Hisato Takagi, Michel Pompeu Sa, Toshiki Kuno Mar 2026

Free Versus In Situ Right Internal Mammary Artery As A Conduit In Coronary Artery Bypass Surgery: A Meta-Analysis, Yuta Kikuchi, Tomoki Sakata, Tomonari Shimoda, Shinichi Fukuhara, Junichi Shimamura, Makoto Hibino, Tsuyoshi Kaneko, Hiroo Takayama, Hisato Takagi, Michel Pompeu Sa, Toshiki Kuno

Department of Medicine Faculty Papers

OBJECTIVES: There is debate regarding the optimal choice for a second conduit in coronary artery bypass grafting. The right internal mammary artery (RIMA) is commonly employed as a second conduit; however, it is unclear whether the free (fRIMA) or in situ (isRIMA) configuration yields superior outcomes. We performed a systematic review and meta-analysis to compare clinical outcomes between fRIMA and isRIMA as the second conduit.

METHODS: A comprehensive search of PubMed (MEDLINE), EMBASE, and CENTRAL was performed through May 2025 to identify studies comparing outcomes in patients undergoing coronary artery bypass grafting with either fRIMA or isRIMA as a second …


Optimal Control And Bifurcation Analysis Of A Predator–Prey Model With Self-Limiting Growth And Predator Disease, Dipo Aldila, Muhammad Akmal Fasya, Bevina D. Handari, Chidozie Williams Chukwu, Olumuyiwa James Peter Mar 2026

Optimal Control And Bifurcation Analysis Of A Predator–Prey Model With Self-Limiting Growth And Predator Disease, Dipo Aldila, Muhammad Akmal Fasya, Bevina D. Handari, Chidozie Williams Chukwu, Olumuyiwa James Peter

Mathematical Modelling and Numerical Simulation with Applications

We propose and analyze an eco-epidemiological predator–prey model that incorporates self-limitation and disease transmission within the predator population. The model is formulated as a system of ordinary differential equations describing logistic prey growth under the interspecific interaction with the predator. On the other hand, the predator population is divided into susceptible and infected classes, whose growth is constrained by prey availability. Three biologically relevant equilibria are identified: predator extinction, disease-free coexistence, and coexistence with endemic disease. The existence and stability of these equilibria are determined by key ecological and epidemiological thresholds, including the basic reproduction number. Using numerical continuation methods, …


Optimal Control Strategies For Infectious Diseases: A Numerical Simulation Approach, M. Abu Salek, Jannatun Nayeem, Romana Yesmin, M. Haider Ali Biswas, M. Humayun Kabir Mar 2026

Optimal Control Strategies For Infectious Diseases: A Numerical Simulation Approach, M. Abu Salek, Jannatun Nayeem, Romana Yesmin, M. Haider Ali Biswas, M. Humayun Kabir

Mathematical Modelling and Numerical Simulation with Applications

Various infectious diseases, such as Tuberculosis and Hepatitis B virus (HBV), caused by Mycobacterium bacteria and hepatitis B virus, respectively, pose serious threats worldwide. This paper examines the spread of these diseases using a mathematical model that incorporates control measures, including vaccination and awareness programs. We use a system of differential equations with control variables and apply Pontryagin's principle to determine optimal control strategies. The stability of the Disease Free Equilibrium (DFE) has been analysed and demonstrated to be both locally and globally asymptotically stable when the basic reproduction number remains below unity, thereby ensuring disease elimination. Furthermore, the Endemic …


How Does High-Tech Entrepreneurship Affect Incumbent Firm Innovation In Regional Innovation Ecosystems?, Beibei Hu Mar 2026

How Does High-Tech Entrepreneurship Affect Incumbent Firm Innovation In Regional Innovation Ecosystems?, Beibei Hu

Double Helix Methodology

High-tech entrepreneurship plays a central role in shaping regional innovation ecosystems, yet the mechanisms through which it affects innovation in incumbent firms remain underexplored. Using firm-level data from the Zhongguancun Science Park (2005–2015), this study investigates the impact of high-tech entrepreneurship on incumbent firms’ innovation. The results reveal that high-tech entrepreneurship significantly enhances innovation among incumbent firms, primarily through R&D investment and human capital. Moreover, this effect is stronger in the electronic information industry and during the development stage. Overall, the study highlights the role of high-tech entrepreneurship in driving the evolution of regional innovation ecosystems. © The Author(s) 2026. …


Modulation Of Pulpal Mmp-8 And Vegf-Alpha By Bioactive Calcium Silicate And Blood Cockle Shell Extract Combination In Rats, Angelia Conny Nidiaty, Noor Hikmah, Kezia Rachellea Mustakim, Wahyuni Suci Dwiandhany, Hafsah Katu, Juni Jekti Nugroho Mar 2026

Modulation Of Pulpal Mmp-8 And Vegf-Alpha By Bioactive Calcium Silicate And Blood Cockle Shell Extract Combination In Rats, Angelia Conny Nidiaty, Noor Hikmah, Kezia Rachellea Mustakim, Wahyuni Suci Dwiandhany, Hafsah Katu, Juni Jekti Nugroho

International Arab Journal of Dentistry

Objectives: This study evaluated MMP-8 and VEGF-Alpha expression in rat dental pulp inflammation after application of bioactive calcium silicate combined with blood cockle shell extract.

Methods: Forty mandibular incisors were randomly assigned to four groups: 100% bioactive calcium silicate (control) and three treatment groups containing 25%, 50%, or 75% shell extract with the remainder calcium silicate. Direct pulp capping was performed, and samples were collected on days 1, 3, 7, and 14.

Results: Immunohistochemistry and one-way ANOVA revealed significant differences in MMP-8 expression on days 1 and 3, and VEGF-Alpha expression across all time points (p < 0.05). The 75% shell extract group showed the lowest MMP-8 and highest VEGF-Alpha expression.

Conclusions: These findings suggest …


Bifurcation Exploration Of Ion Acoustic Solitons Formation Of A Nonlinear Beta Fractional Kadomtsev-Petviashvili Burger Model In Plasma State, Mst. Razia Pervin, Alrazi Abdeljabbar, Fahad Sameer Alshammari, Mst. Shekha Khatun, Harun Or-Roshid Mar 2026

Bifurcation Exploration Of Ion Acoustic Solitons Formation Of A Nonlinear Beta Fractional Kadomtsev-Petviashvili Burger Model In Plasma State, Mst. Razia Pervin, Alrazi Abdeljabbar, Fahad Sameer Alshammari, Mst. Shekha Khatun, Harun Or-Roshid

Mathematical Modelling and Numerical Simulation with Applications

This research presents an extensive investigation of Ion acoustic soliton dynamics governed by a Beta-fractional Kadomtsev-Petviashvili-Burgurs (KPB) model. By engaging the planar dynamical system scheme in aggregation with the extended $(\phi, \psi)$ expansion, Kudryashov expansion, and the NMKM analytic schemes, we create a broad class of exact nonlinear pattern wave solutions. The local stability edifice of the fractional plasma model is explored through bifurcation theory, enabling the far-reaching classification of all admissible phase diagrams. Conforming Ion acoustic wave structures allied with every detour alignment are systematically assembled. Owing to the fractional and dissipative appearances of the model, an all-embracing assortment …


Employing Effective Solution Methods For Caputo-Based Sequential Fractional Models, Eman A. A. Ziada, Mohamed F. Abouelenein, Hijaz Ahmad, Monica Botros Mar 2026

Employing Effective Solution Methods For Caputo-Based Sequential Fractional Models, Eman A. A. Ziada, Mohamed F. Abouelenein, Hijaz Ahmad, Monica Botros

Mathematical Modelling and Numerical Simulation with Applications

This paper investigates a class of nonlinear sequential singular fractional differential equations (FDEs) involving Caputo derivatives. This type of equation has several key advantages that enhance its value, such as capturing memory and hereditary effects. Viscoelastic materials and anomalous diffusion, as well as biological systems, can take advantage of this feature. In addition, fractional derivatives possess a sequential structure that enables the implementation of multiscale processes and hierarchical memory responses. Moreover, it provides an effective and flexible framework for solving differential equations compared to classical differential equations. It can therefore be used to model complex systems in physics, biology, and …


Numerical Simulations And Hyers-Ulam Stability Of A Novel Nonlocal Anthropogenic Cutaneous Leishmaniasis Mathematical Model, Khalid Fanoukh Al Oweidi, Zakirullah -, Kamal Shah, Thabet Abdeljawad Mar 2026

Numerical Simulations And Hyers-Ulam Stability Of A Novel Nonlocal Anthropogenic Cutaneous Leishmaniasis Mathematical Model, Khalid Fanoukh Al Oweidi, Zakirullah -, Kamal Shah, Thabet Abdeljawad

Mathematical Modelling and Numerical Simulation with Applications

In this work, the fractal-fractional Atangana-Baleanu derivative with the Mittag-Leffler kernel is employed to capture the memory and hereditary effects inherent to anthropogenic cutaneous leishmaniasis transmission dynamics. The Banach fixed-point theorem and contraction mapping principle are used to prove the existence and uniqueness of solutions, while Hyers-Ulam stability of the system is analyzed to demonstrate the robustness of solutions with respect to small perturbations. Using a nonlinear least-squares approach, model parameters and fractional order are estimated using epidemiological data from the World Health Organization. The basic reproduction number $R_0 = 0.53$ indicates that the disease is under control after adding …


Exact Soliton Solutions Of The Nonlinear Time-Fractional Schrödinger Equation Via Atangana–Baleanu And M-Truncated Operators, Bahadır Kopçasiz, Fatma Nur Kaya Sağlam, Mehmet Şenol Mar 2026

Exact Soliton Solutions Of The Nonlinear Time-Fractional Schrödinger Equation Via Atangana–Baleanu And M-Truncated Operators, Bahadır Kopçasiz, Fatma Nur Kaya Sağlam, Mehmet Şenol

Mathematical Modelling and Numerical Simulation with Applications

The main objective of this work is to obtain exact soliton solutions for a nonlinear time-fractional equation model describing wave profiles arising in various physical systems. To derive different wave structures associated with the considered model, two analytical techniques are employed: the extended G'\G^2-expansion method and the modified auxiliary equation (MAE) approach. A wave transformation is applied to reduce the nonlinear time-fractional equation to a nonlinear ordinary differential equation (NLODE) by means of the M-truncated and Atangana-Baleanu (AB) fractional operators. Several classes of solutions, including exponential, hyperbolic, and trigonometric wave forms, are obtained. Over and above the analytical results, graphical …


Dynamical Analysis And Optimal Control Of The Mpox Transmission Model With Stratified Susceptibility, Tuhfatul Janan, Fatmawati Fatmawati, Cicik Alfiniyah, Santi Martini, Dipo Aldila, Agus Hasan Mar 2026

Dynamical Analysis And Optimal Control Of The Mpox Transmission Model With Stratified Susceptibility, Tuhfatul Janan, Fatmawati Fatmawati, Cicik Alfiniyah, Santi Martini, Dipo Aldila, Agus Hasan

Mathematical Modelling and Numerical Simulation with Applications

This study develops a mathematical model of Mpox transmission that combines stratified susceptibility (low-risk and high-risk groups) with vaccinated and asymptomatically infected compartments. The analysis of the model begins with examining the well-posedness, boundedness, and nonnegativity conditions for the solutions. The local stabilities of the equilibria are examined through the Jacobian matrix and phase plane analysis, while the global stabilities are provided through Lyapunov functions. The estimated parameters are verified using epidemiological data on Mpox cases in the United States, with an MAPE of 2.20% and R_0 > 1, indicating that Mpox remains endemic. Sensitivity analysis indicates that the contact rate …


Emergent Operator Logic: A Foundational Framework For Dynamic Reasoning And Generative Intelligence, Mona Gharib, Abduallah Gamal, Muhammad Nawaz, Basma Nasir Mar 2026

Emergent Operator Logic: A Foundational Framework For Dynamic Reasoning And Generative Intelligence, Mona Gharib, Abduallah Gamal, Muhammad Nawaz, Basma Nasir

Neutrosophic Systems with Applications

This paper introduces Emergent Operator Logic (EOL), a framework that treats propositions as continuous operators $F_p:X \rightarrow X$ on a complete metric state space $( X,d )$ and evaluates truth after action via a continuous valuation $V:X \rightarrow [ 0,1 ]$. Logical composition is realized by three operator-level connectives: sequential $p \circ q$(causal order), parallel $p\parallel q$(1-Lipschitz cooperative blend), and the emergent synthesis $E( p,q ) = \frac12( F_p \circ F_q + F_q \circ F_p )$, which symmetrizes non-commuting actions. We provide a Hilbert-style proof system (sound), an algebraic semantics via E-algebras, and show that the category of E-algebras is …


Regulation Of Zygotic Genome Activation By The Nucleocytoplasmic Ratio, Lily Acker, Hui Chen Mar 2026

Regulation Of Zygotic Genome Activation By The Nucleocytoplasmic Ratio, Lily Acker, Hui Chen

Faculty Publications

During early development, embryos undergo the maternal-to-zygotic transition (MZT), when control of development shifts from maternal factors to the newly activated zygotic genome. Decades of studies in various model organisms suggest that the nucleocytoplasmic (N/C) ratio is a key regulator of zygotic genome activation (ZGA), though this relationship is more nuanced in some organisms than others. Changing the nuclear content, nucleus size or cell size has been shown to shift the timing of ZGA. Mechanistically, the N/C ratio is linked to fundamental cellular processes that regulate genome activities, including nuclear import, repressor titration, activator accumulation, cell cycle lengthening, and chromatin …


High-Power Dual-Channel Chamber For High-Frequency Magnetic Neuromodulation, Xiaoyang Tian, Hui Wang, Boshuo Wang, Jinshui Zhang, Dong Yan, Jeannette Ingabire, Samantha Coffler, Guillaume Duret, Quoc-Khanh Pham, Gang Bao, Junzhe Wang, Ashok Veeraraghavan, Jacob T Robinson, Stefan M Goetz, Angel V Peterchev Mar 2026

High-Power Dual-Channel Chamber For High-Frequency Magnetic Neuromodulation, Xiaoyang Tian, Hui Wang, Boshuo Wang, Jinshui Zhang, Dong Yan, Jeannette Ingabire, Samantha Coffler, Guillaume Duret, Quoc-Khanh Pham, Gang Bao, Junzhe Wang, Ashok Veeraraghavan, Jacob T Robinson, Stefan M Goetz, Angel V Peterchev

Faculty, Staff and Students Publications

Objective. Several novel methods, including magnetogenetics and magnetoelectric stimulation, use high frequency alternating magnetic fields to precisely manipulate neural activity. To quantify the behavioral effects of such interventions in a freely moving mouse, we developed a dual-channel magnetic chamber, specifically designed for rate-sensitive magnetothermal-genetic stimulation, and adaptable for other uses of alternating magnetic fields.

Approach. Through an optimized coil design, the system allows independent control of two spatially orthogonal uniform magnetic fields delivered at different frequencies within a 10 × 10 × 6 cm3 chamber suitable for mouse studies. The two channels have nominal frequencies of 50 and 550 kHz …


Toxicity, Chemistry, And Public Health Relevance Of Emerging Nicotine Analog Vapes, Pods, And Pouches., Rhea Raghu, Mohana Sengupta, Karen Lin, Felix Effah, Robert M. Strongin, Irfan Rahman Mar 2026

Toxicity, Chemistry, And Public Health Relevance Of Emerging Nicotine Analog Vapes, Pods, And Pouches., Rhea Raghu, Mohana Sengupta, Karen Lin, Felix Effah, Robert M. Strongin, Irfan Rahman

Chemistry Faculty Publications and Presentations

Electronic nicotine delivery system manufacturers, such as Charlie's Holdings Inc., ECBlend, Outlaw, and NicRiver, have recently introduced nicotine analogs, such as 6-methyl nicotine, 6-MN ("Metatine"), and nicotinamide, NA ("Nixamide," "Nixodine," or "Nixotin-free base and salt") in products to circumvent the U.S. FDA's premarket tobacco product application (PMTA) requirements. Marketed as "tobacco-free," "PMTA-exempt," or "FDA-approved," these compounds now appear in oral nicotine pouches and disposable bars/vapes from brands such as Outlaw Dip, Kumi-Six, SBX, Katchmi, and Spree Bar under proprietary labels including "NoNic6," "Metatine," or "NIC-SAFE." These products often mimic the appeal of conventional nicotine delivery systems, with extensive use of …


Chronic Post-Mastectomy Pain: Insights Into Mechanisms, Prevention, And Treatment Approaches, Abdulaziz H. Algain Mar 2026

Chronic Post-Mastectomy Pain: Insights Into Mechanisms, Prevention, And Treatment Approaches, Abdulaziz H. Algain

Journal of Medical Rehabilitation Science

Chronic post-mastectomy pain (CPMP) is a prevalent and significant concern for many breast cancer surgery patients, affecting between 25% and 60% of females within the first year after surgery. This multifactorial condition arises from a combination of peripheral nerve injury, central sensitization, and immune-mediated inflammation. Although no single intervention can fully prevent CPMP, a comprehensive, multidisciplinary approach that addresses the biological, psychological, and social aspects of pain is crucial for enhancing the quality of life for breast cancer survivors. It is often underrecognized by clinicians, who may attribute pain to the expected postoperative recovery process, while patients sometimes accept discomfort …


Prevalence And Association Between Major Depressive Disorder And Cognitive Impairment In Hemodialysis Patients At King Abdulaziz University Hospital, Jeddah, Saudi Arabia, Faten N. Alzaben Mar 2026

Prevalence And Association Between Major Depressive Disorder And Cognitive Impairment In Hemodialysis Patients At King Abdulaziz University Hospital, Jeddah, Saudi Arabia, Faten N. Alzaben

Journal of Medical Rehabilitation Science

Objectives: Patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis experience a substantial psychological and cognitive burden. This study aimed to determine the prevalence of major depressive disorder (MDD) and examine its association with cognitive impairment among patients receiving hemodialysis. Materials and Methods: A cross-sectional study was conducted among 30 consecutive patients aged 18–65 years undergoing maintenance hemodialysis at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Major depressive disorder was diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), with cognitive impairment defined as a MoCA score …


Defining The Palette Of Biodeterrence: Appreciating A Broader Toolkit, Diane Dieuliis, James Giordano Mar 2026

Defining The Palette Of Biodeterrence: Appreciating A Broader Toolkit, Diane Dieuliis, James Giordano

Strategic Insights

Biological threats present unique challenges to traditional deterrence models due to their dual-use nature, difficulties in attribution, and rapidly evolving scientific landscape. In this commentary, the authors argue that deterrence by denial, while essential, is insufficient on its own to address contemporary biothreats. They propose a broader framework that integrates deterrence by disruption and capability diminishment to interfere with and reduce adversaries’ ability to develop and employ biological weapons. This approach emphasizes coordinated efforts across scientific, technological, economic, intelligence, and policy domains, as well as collaboration with public health and international partners. By shaping the conditions under which biological weapons …