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The Fall Of America's Final Free Labor Market: Considering The New Age College Athlete As An Employee Under The Nlra And Flsa, Ethan Schaaf Mar 2026

The Fall Of America's Final Free Labor Market: Considering The New Age College Athlete As An Employee Under The Nlra And Flsa, Ethan Schaaf

Kentucky Law Journal

No abstract provided.


Reaching For Starz: The Negative Impact Of Creating Limitations On Damages In Timely Copyright Claims, Lindley Williams Mar 2026

Reaching For Starz: The Negative Impact Of Creating Limitations On Damages In Timely Copyright Claims, Lindley Williams

Kentucky Law Journal

No abstract provided.


Against Activist Cooperation Agreements, Jennifer O'Hare Mar 2026

Against Activist Cooperation Agreements, Jennifer O'Hare

Kentucky Law Journal

No abstract provided.


Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss Mar 2026

Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss

Progress in Scale Modeling, an International Journal

The phenomenon of Taylor or shear-induced dispersion of a non-passive scalar field in a pulsatile pipe flow is investigated, accounting for the scalar field's influence on fluid density and transport coefficients. By employing multiple scale analysis, an effective one-dimensional, unsteady mixing problem for the scalar field is obtained, which includes the diffusion coefficient for shear-induced dispersion. The resulting governing equations are applicable to a range of scalar transport problems in pulsatile pipe flows.


Methane Emissions From Underground Coal Mines, Marcelo Guzman, Thomas Parris, Stephen Greb, Cortland F. Eble, Sean Bailey Mar 2026

Methane Emissions From Underground Coal Mines, Marcelo Guzman, Thomas Parris, Stephen Greb, Cortland F. Eble, Sean Bailey

Mechanical Engineering Faculty Publications

Methane emissions from Kentucky underground coal mines were measured using near-infrared spectrometers deployed on a vehicle, an airplane, and a small uncrewed aerial system (sUAS), offering insights into the effectiveness of these methods under real-world conditions. From 2021–2022, surveys covered 14 active, 4 inactive, and 4 abandoned mines across Kentucky’s coal-producing basins. Vehicle-based surveys at 13 active mines detected methane anomalies at 9 sites with anomaly lengths spanning tens to hundreds of meters and peak emissions of 665 ± 229 kg h–1 from two Cardinal mine fans. Airborne GHGSat surveys identified anomalies at 3 sites, including a peak of 1062 …


Dvr Service Evaluation And Fee Sufficiency Study, Mallory Brown, Andrew Martin, Jeeyen Koo, Jennifer Walton Mar 2026

Dvr Service Evaluation And Fee Sufficiency Study, Mallory Brown, Andrew Martin, Jeeyen Koo, Jennifer Walton

Kentucky Transportation Center Research Report

The Kentucky Transportation Cabinet’s (KYTC) Department of Vehicle Regulation (DVR) administers numerous fees and taxes. Many administered by the two divisions in DVR — Motor Vehicle Licensing (DMVL) and Motor Carriers (DMC) — have remained unchanged for many years despite salary increases, the adoption of more complex and expensive technologies, and inflation raising administrative costs. This report provides in-depth assessments of 10 fees and taxes (selected by division administrators). Six are administered by DMVL — certificate of title, duplicate title, vehicle title history report, additional registration fee, reflectorized license plate fund, and trailer registrations — and four are managed by …


Sacbe 1 And Classic Maya Urban Culture, Traci Ardren, Scott R. Hutson, Travis W. Stanton, Patrick Rohrer, Justin P. Lowry Mar 2026

Sacbe 1 And Classic Maya Urban Culture, Traci Ardren, Scott R. Hutson, Travis W. Stanton, Patrick Rohrer, Justin P. Lowry

Anthropology Faculty Publications

One of the most significant engineering accomplishments of Maya civilization is Sacbe 1, a raised road connecting the ancient urban centers of Yaxuna and Coba. Using new lidar data in concert with excavation, epigraphic inscriptions, and landscape reconnaissance, we show that settlement and an urban experience emanated westward from Coba along the sacbe. The leaders of Coba - in particular, an ambitious seventh-century queen - used the sacbe to expand the political and cultural influence of their dynasty into the center of the peninsula while securing territory and resources. Gaps in the sacbe, precise delineation of its many curves, and …


Synthesis And Structures Of Ru(Ii)-P-Cymene Sandwich Complexes With Electron-Withdrawing Cyclopentadienyl Ligands, Uttam R. Pokharel, Sean Parkin, John P. Selegue Mar 2026

Synthesis And Structures Of Ru(Ii)-P-Cymene Sandwich Complexes With Electron-Withdrawing Cyclopentadienyl Ligands, Uttam R. Pokharel, Sean Parkin, John P. Selegue

Chemistry Faculty Publications

A modular synthetic route has been developed to prepare a new series of cationic ruthenium(II) complexes with electron-withdrawing 1,2-diacylcyclopentadienyl ligands. The 2-acyl-6-hydroxyfulvenes were synthesized from cyclopentadienide and acyl chlorides and converted to Tl(I) cyclopentadienyl salts using Tl2SO4/KOH. Transmetalation with [Ru(η6-p-cymene)(μ-Cl)Cl]2 followed by PF6− metathesis gives the complexes [Ru{η5-1,2-C5H3(CO–R)2}(η6-p-cymene)][PF6] (R = t-Bu, p-Tol, p-ClC6H4, p-IC6H4) in moderate to high yields. The new compounds were characterized by NMR and IR spectroscopy; mass spectrometry …


Intermittent Hypoxemia And Brain Injury Biomarker S100b In Preterm Infants, Elie G. Abu Jawdeh, Linda J. Van Eldik, Jennifer Stevenson, Abhijit Patwardhan, Philip M. Westgate, Lina Chalak, Richard J. Martin, Henrietta S. Bada Feb 2026

Intermittent Hypoxemia And Brain Injury Biomarker S100b In Preterm Infants, Elie G. Abu Jawdeh, Linda J. Van Eldik, Jennifer Stevenson, Abhijit Patwardhan, Philip M. Westgate, Lina Chalak, Richard J. Martin, Henrietta S. Bada

Epidemiology and Environmental Health Faculty Publications

Abstract – Introduction: Intermittent hypoxemia (IH) is common in preterm infants and linked to brain injury. S100B is a glial-derived protein that rises early after neural injury and can be measured noninvasively in urine. We evaluated the relationship between IH burden and urinary S100B in preterm infants of ≤32 weeks’ gestation. Methods: Preterm infants of ≤32 weeks’ gestation were prospectively enrolled. Oxygen saturation was continuously monitored, and IH profiles were quantified using validated algorithms. Urine S100B was measured by ultrasensitive immunoassay and normalized for urinary creatinine. Infants with severe intraventricular hemorrhage were excluded. Weighted Spearman correlations examined associations between IH …


Mauve, Luca Cortese, Adam Brian Watts, Jiayi Sun, Sriram Sankar, Barbara Catinella, Toby Brown, Alessandro Boselli, Pavel Jáchym, Tutku Kolcu, Sabine Thater, Jesse Van De Sande, Vicente Villanueva Feb 2026

Mauve, Luca Cortese, Adam Brian Watts, Jiayi Sun, Sriram Sankar, Barbara Catinella, Toby Brown, Alessandro Boselli, Pavel Jáchym, Tutku Kolcu, Sabine Thater, Jesse Van De Sande, Vicente Villanueva

Physics and Astronomy Faculty Publications

We present a multiphase study of the star-formation-driven outflow in the Virgo galaxy NGC 4383, combining ALMA CO(2-1) data with deep MeerKAT Hi imaging and MUSE spectroscopy obtained as part of the Multiphase Astrophysics to Unveil the Virgo Environment (MAUVE) program. Our previous work revealed a spectacular ionised outflow, but the effect of the outflow on the cold phase remained unclear. Our analysis shows that potentially outflowing molecular gas is detected only within the inner 1 kpc above the disc, where CO clouds exhibit disturbed kinematics and spatial correspondence with the ionisation cone. At larger heights, the CO surface brightness …


Phase 1 Open-Label Study Of Asp9801, An Oncolytic Virus, In Patients With Advanced Or Metastatic Solid Tumors, John L. Villano, Jason J. Luke, Ricklie Julian, Christos Fountzilas, Manish R. Patel, Michael J. Chisamore, Pranob Bhattacharya, Shigeru Takeshita, Serguei Soukharev, Shunsuke Yamada, Leshi Zhang, Kristopher P. Wentzel Feb 2026

Phase 1 Open-Label Study Of Asp9801, An Oncolytic Virus, In Patients With Advanced Or Metastatic Solid Tumors, John L. Villano, Jason J. Luke, Ricklie Julian, Christos Fountzilas, Manish R. Patel, Michael J. Chisamore, Pranob Bhattacharya, Shigeru Takeshita, Serguei Soukharev, Shunsuke Yamada, Leshi Zhang, Kristopher P. Wentzel

Neurology Faculty Publications

Purpose ASP9801, an oncolytic virus encoding interleukin-7 and interleukin-12, was assessed for safety, tolerability, pharmacokinetics, and antitumor activity in patients with advanced solid tumors in a Phase 1 study. Methods The study comprised Part 1 ASP9801 monotherapy dose escalation and Part 2 dose expansion with ASP9801 monotherapy or plus pembrolizumab. Each part was divided into Groups A (ASP9801 injection into cutaneous/subcutaneous lesions) and B (ASP9801 injection into visceral lesions). Primary objectives were safety and maximum tolerated dose and/or recommended Phase 2 dose expansion (RP2D); secondary objectives included antitumor activity and pharmacokinetics. Results In dose escalation, 17 and 10 patients in …


Fiscal Year 2023 Fhwa-536 Report For The Kentucky Transportation Cabinet, Doug Kreis, Candice Wallace, Bryan Gibson, Sarah Mccormack Feb 2026

Fiscal Year 2023 Fhwa-536 Report For The Kentucky Transportation Cabinet, Doug Kreis, Candice Wallace, Bryan Gibson, Sarah Mccormack

Kentucky Transportation Center Research Report

Every other year, the Federal Highway Administration (FHWA) requires that states submit a Local Highway Finance Report (FHWA-536) to the agency. This report summarizes data on local highway finances and is used by FHWA to evaluate relationships between and changes in revenues, expenditures and investment patterns, and financial trends. This report presents information submitted by Kentucky in its fiscal year (FY) 2023 FHWA-536. Total receipts from local, state, and federal sources used for road and street infrastructure equaled approximately $1.11 billion. Local sources of funding accounted for the largest share of total receipts (47%), followed by state government sources (45%), …


Kytc Digital Project Delivery Phase 1 Summary, Rachel Catchings Feb 2026

Kytc Digital Project Delivery Phase 1 Summary, Rachel Catchings

Kentucky Transportation Center Research Report

The Kentucky Transportation Cabinet (KYTC) launched its Digital Project Delivery (DPD) Initiative in September 2020 with the goal of expanding the use of digitally formatted plan and project information throughout the transportation asset life cycle, from project delivery through asset management. KYTC retained Kentucky Transportation Center (KTC) staff with expertise in construction and design to facilitate DPD implementation. This document summarizes DPD-related efforts undertaken by the Cabinet over the past five years. Key activities completed during this period include a survey of Kentucky Association of Highway Contractors members to document their perspectives on design file usage and preferences, coordinating multiple …


Kentucky Cdl Adjudication Pilot And Compliance Needs Study, Jeeyen Koo, Andrew Martin, Jennifer Walton Feb 2026

Kentucky Cdl Adjudication Pilot And Compliance Needs Study, Jeeyen Koo, Andrew Martin, Jennifer Walton

Kentucky Transportation Center Research Report

This report examines trends in how Kentucky District Courts have adjudicated charges related to commercial driver’s license (CDL) and commercial motor vehicles (CMVs). Using court data, researchers evaluated historical patterns in charge filing volumes as well as conviction, dismissal, amendment, and diversion rates. Between 2002 and 2024, conviction rates declined and dismissals increased. Convictions peaked in the mid-70% range in the early 2000s, but fell to the mid-50% range by 2024. Speeding and other serious traffic violations — many of which are advanceable offenses — were dismissed or amended at rates that could have substantively affected the integrity of CDL …


Fiscal Year 2024 Fhwa-536 Report For The Kentucky Transportation Cabinet, Doug Kreis, Candice Wallace, Bryan Gibson, Sarah Mccormack Feb 2026

Fiscal Year 2024 Fhwa-536 Report For The Kentucky Transportation Cabinet, Doug Kreis, Candice Wallace, Bryan Gibson, Sarah Mccormack

Kentucky Transportation Center Research Report

Every other year, the Federal Highway Administration (FHWA) requires that states submit a Local Highway Finance Report (FHWA-536) to the agency. This report summarizes data on local highway finances and is used by FHWA to evaluate relationships between and changes in revenues, expenditures and investment patterns, and financial trends. This report presents information submitted by Kentucky in its fiscal year (FY) 2024 FHWA-536. Total receipts from local, state, and federal sources used for road and street infrastructure equaled approximately $1.27 billion. Local sources of funding accounted for the largest share of total receipts (50%), followed by state government sources (41%), …


Duration And Properties Of The Embedded Phase Of Star Formation In 37 Nearby Galaxies From Phangs-Jwst, Lise Ramambason, Mélanie Chevance, Jaeyeon Kim, Francesco Belfiore, J. M. Diederik Kruijssen, Andrea Romanelli, Amirnezam Amiri, Médéric Boquien, Ryan Chown, Daniel A. Dale, Simthembile Dlamini, Oleg V. Egorov, Ivan Gerasimov, Simon C.O. Glover, Kathryn Grasha, Hamid Hassani, Hwihyun Kim, Kathryn Kreckel, Hannah Koziol, Adam K. Leroy, José Eduardo Méndez-Delgado, Justus Neumann, Lukas Neumann, Hsi An Pan, Debosmita Pathak, Karin Sandstrom, Sumit K. Sarbadhicary, Eva Schinnerer, Jiayi Sun, Jessica Sutter, David A. Thilker, Leonardo Ubeda Feb 2026

Duration And Properties Of The Embedded Phase Of Star Formation In 37 Nearby Galaxies From Phangs-Jwst, Lise Ramambason, Mélanie Chevance, Jaeyeon Kim, Francesco Belfiore, J. M. Diederik Kruijssen, Andrea Romanelli, Amirnezam Amiri, Médéric Boquien, Ryan Chown, Daniel A. Dale, Simthembile Dlamini, Oleg V. Egorov, Ivan Gerasimov, Simon C.O. Glover, Kathryn Grasha, Hamid Hassani, Hwihyun Kim, Kathryn Kreckel, Hannah Koziol, Adam K. Leroy, José Eduardo Méndez-Delgado, Justus Neumann, Lukas Neumann, Hsi An Pan, Debosmita Pathak, Karin Sandstrom, Sumit K. Sarbadhicary, Eva Schinnerer, Jiayi Sun, Jessica Sutter, David A. Thilker, Leonardo Ubeda

Physics and Astronomy Faculty Publications

Light reprocessed by dust grains emitting in the infrared enables the study of the physics at play in dusty embedded regions, where ultraviolet and optical wavelengths are attenuated. Infrared telescopes such as JWST have made it possible to study the earliest feedback phases, when stars are shielded by cocoons of gas and dust. Comprehending this phase is crucial for unravelling the effects of feedback from young stars that leads to their emergence and the dispersal of their host molecular clouds. Here we show that the transition from the embedded to the exposed phase of star formation is short (< 4 Myr) and sometimes almost absent (< 1 Myr) across a sample of 37 nearby star-forming galaxies covering a wide range of morphologies, from massive barred spirals to irregular dwarfs. The short duration of the dust-clearing timescales suggests a predominant role of pre-supernova feedback mechanisms in revealing newborn stars, confirming previous results on smaller samples and allowing, for the first time, a statistical analysis of their dependencies. We find that the timescales associated with mid-infrared emission at 21 μm, tracing a dust-embedded feedback phase, are controlled by a complex interplay between giant molecular cloud properties (masses and velocity dispersions) and galaxy morphology. We report relatively longer durations of the embedded phase of star formation in barred spiral galaxies, while this phase is significantly reduced in low-mass irregular dwarf galaxies. We discuss tentative trends with gas-phase metallicity, which may favor faster cloud dispersal at low metallicities.


From Leaky Pipelines To Watering Cans, Samantha Fladd, Sarah Kurnick, Laura E. Heath-Stout, Nala K. Williams, Sarah Simeonoff, Sasha Buckser, Katelyn J. Bishop, Scott R. Hutson, Jessica Maclellan, Marie Matsuda, Sarah E. Oas, Jocelyne M. Ponce, Bruno Athie Teruel, Jaycee Castro, Breeanna Charolla, Adriana M. De León, Luisa Escobar Galo, Lydia D. Evans, Isabella N. Garcia, Kelsey Hoppes, Elena Lompe Feb 2026

From Leaky Pipelines To Watering Cans, Samantha Fladd, Sarah Kurnick, Laura E. Heath-Stout, Nala K. Williams, Sarah Simeonoff, Sasha Buckser, Katelyn J. Bishop, Scott R. Hutson, Jessica Maclellan, Marie Matsuda, Sarah E. Oas, Jocelyne M. Ponce, Bruno Athie Teruel, Jaycee Castro, Breeanna Charolla, Adriana M. De León, Luisa Escobar Galo, Lydia D. Evans, Isabella N. Garcia, Kelsey Hoppes, Elena Lompe

Anthropology Faculty Publications

Despite improvement over the past few decades, particularly for white, cisgender women, intersectional gender-based inequality remains prominent within anthropological archaeology and beyond. Building on critiques of the leaky pipeline metaphor laid out in the introduction to this themed issue, and drawing on Black, Indigenous, and Posthumanist Feminisms, we advocate for a metaphorical shift focused on care, inclusivity, and diversity—that of a garden. The garden metaphor provides a way to express and explore the complex and intertwined ways disciplinary norms, institutions, and individuals structure and shape experiences in archaeology. After reviewing the garden metaphor and summarizing previous suggestions for improving equity …


Successful Biliary Re-Cannulation And Neo-Anastomosis Creation In Complete Bile Duct Occlusion Or Disruption Using A Combination Of Interventional Radiology And Endoscopic Techniques, Joshua G. Fricker, Tarik Babar, Husameddin El Khudari, Ali Ahmed, Dalton Norwood, Sergio A. Sánchez-Luna, Eric Bready, Ramzi Mulki, Kondal Kyanam, Shajan Peter, Andrew Gunn Feb 2026

Successful Biliary Re-Cannulation And Neo-Anastomosis Creation In Complete Bile Duct Occlusion Or Disruption Using A Combination Of Interventional Radiology And Endoscopic Techniques, Joshua G. Fricker, Tarik Babar, Husameddin El Khudari, Ali Ahmed, Dalton Norwood, Sergio A. Sánchez-Luna, Eric Bready, Ramzi Mulki, Kondal Kyanam, Shajan Peter, Andrew Gunn

Radiology Faculty Publications

Aims: Biliary strictures are a known complication of hepatobiliary and pancreatic surgeries. This retrospective descriptive series highlights six consecutive patients with complete bile duct occlusion or disruption who required a multidisciplinary approach with a combination of interventional radiology (IR) and endoscopic techniques to either re-cannulate or create a neo-anastomosis in the biliary system. Methods and Results: The biliary system was either re-cannulated or a neo-anastomosis was created using a small gauge needle (N = 3), a rendezvous procedure (N = 1), a radiofrequency ablation wire (N = 1), and the back end of a wire (N = 1). There was …


The American College Of Radiology Diagnostic Fluoroscopy Dose Index Registry Pilot, Steve D. Mann, Donald L. Miller, Grant Fong, Allen R. Goode, Emily L. Marshall, Thomas Nishino, Pavlina Boxx, Liqiang Ren, Celalettin Topbas, Alan H. Schoenfeld, Vivek Singh, Jie Zhang Feb 2026

The American College Of Radiology Diagnostic Fluoroscopy Dose Index Registry Pilot, Steve D. Mann, Donald L. Miller, Grant Fong, Allen R. Goode, Emily L. Marshall, Thomas Nishino, Pavlina Boxx, Liqiang Ren, Celalettin Topbas, Alan H. Schoenfeld, Vivek Singh, Jie Zhang

Radiology Faculty Publications

Background: The ACR Diagnostic Fluoroscopy Dose Index Registry (DIR-Fluoro) is expanding to include diagnostic fluoroscopy. Variations in dose reference points and overhead radiography events may introduce unique challenges for benchmarking. Purpose: To survey the technological status and dosimetric performance of fluoroscopes participating in the DIR-Fluoro pilot project, focusing on longitudinal stability and variability of fluoroscopic dose reporting accuracy across multiple institutions and vendors. Methods: Sixty-six fluoroscopic systems from nine institutions (24 facilities) were surveyed for facility type, fluoroscope type, image receptor type, age, dose reporting capabilities, and other key features. Of these, 56 were evaluable. Semi-annual measurements assessed reference air …


Toward An Emerging Public Health Paradigm, Rod Wallace, Katherine Frels, Maria Itria Ibba, Conrad Lyford, Devin Rose, David Baltensperger, Jan A. Delcour, Steven Greenspan, Alison Lovegrove, Barbara Schneeman, Peter Shewry, Edward Souza, William W. Wilson, Gary W. Yohe, Jim Anderson, George Annor, Jayne Bock, Claudia Carter, Brett Carver, Jianli Chen, Edward C. Deehan, Noah Dewitt, Lisa Diewald, Jason Donovan, Corrine K. Hanson, David Holding, Amir Ibrahim, Mariah Jackson Feb 2026

Toward An Emerging Public Health Paradigm, Rod Wallace, Katherine Frels, Maria Itria Ibba, Conrad Lyford, Devin Rose, David Baltensperger, Jan A. Delcour, Steven Greenspan, Alison Lovegrove, Barbara Schneeman, Peter Shewry, Edward Souza, William W. Wilson, Gary W. Yohe, Jim Anderson, George Annor, Jayne Bock, Claudia Carter, Brett Carver, Jianli Chen, Edward C. Deehan, Noah Dewitt, Lisa Diewald, Jason Donovan, Corrine K. Hanson, David Holding, Amir Ibrahim, Mariah Jackson

Animal and Food Sciences Faculty Publications

An emerging paradigm in public health focuses on enhancing nutrition in existing food staples to reduce chronic disease at the population scale, rather than relying on individuals to change their behavior. This paradigm leverages plant and animal breeding, production practices, and processing to enhance nutrition, whereby foods consumed by millions can be improved at low incremental cost. This article supports and operationalizes this paradigm, illustrating the potential to improve diets through a case study that increases the arabinoxylan fiber content of commodity wheat through classical plant breeding (a non-GMO technology). The approach described in this article proposes to link agricultural …


High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann Jan 2026

High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann

Physiology Faculty Publications

Genetic diseases such as ion channelopathies substantially burden human health. Existing treatments are limited and not genotype specific. Here, we report a 2-step high-throughput approach to rapidly identify drug candidates for repurposing as genotype-specific therapy. We first screened 1,680 medicines using a thallium-flux trafficking assay against Kv11.1 gene variants causing long QT syndrome (LQTS), an ion channelopathy associated with fatal cardiac arrhythmia. We identified evacetrapib as a suitable drug candidate that improves membrane trafficking and activates channels. We then used deep mutational scanning to prospectively identify all Kv11.1 missense variants in an LQTS hotspot region responsive to treatment with evacetrapib. …


Sustained Increase In Extracellular Atp In The Lung Induced By Chronic Inhalation Exposure To Nitrogen Dioxide, Nai Ju Chan, Yueh Yin Chen, Chun Chun Hsu, You Shuei Lin, Maxwell Zakeri, Mehdi Khosravi, Lu Yuan Lee Jan 2026

Sustained Increase In Extracellular Atp In The Lung Induced By Chronic Inhalation Exposure To Nitrogen Dioxide, Nai Ju Chan, Yueh Yin Chen, Chun Chun Hsu, You Shuei Lin, Maxwell Zakeri, Mehdi Khosravi, Lu Yuan Lee

Physiology Faculty Publications

Nitrogen dioxide (NO2) is an environmental air pollutant and a potent oxidant. Epidemiological studies have revealed a close association between chronic cough and long-term inhalation exposure to NO2. ATP can be released from airway/lung epithelial cells upon inhalation exposure to oxidants, and convincing evidence established in recent clinical studies indicated that extracellular ATP in the respiratory tract plays an important role in the pathogenesis of refractory chronic cough. However, whether inhalation exposure to NO2 elevates the ATP release in the lung is not yet known. Results of this study showed: 1) in awake rats, acute …


Study Of Clustering Technique And Communication Topologies For Cooperative Control-Based Volt-Var Optimization, Gaurav Yadav, Yuan Liao, Dan M. Ionel Jan 2026

Study Of Clustering Technique And Communication Topologies For Cooperative Control-Based Volt-Var Optimization, Gaurav Yadav, Yuan Liao, Dan M. Ionel

Electrical and Computer Engineering Faculty Publications

Introducing renewable distributed generation (DG) in the power distribution system causes rapid voltage fluctuations due to its intermittency. This intermittency renders conventional voltage regulation devices such as on-load tap changers (OLTCs) and capacitor banks (CBs) inefficient to regulate rapid voltage changes and leads to reduced equipment lifetime and high operation and maintenance costs. Hence, this calls for non-conventional methods to mitigate such voltage fluctuations. This paper presents a cooperative control-based method aimed to optimally control the reactive power of DG inverters to mitigate the voltage deviations by establishing communication among the DG nodes, and between DG and non-DG nodes. This …


Electromagnetic Formation Flying Using Alternating Magnetic Field Forces And Control Barrier Functions For State And Input Constraints, Sumit Suryakant Kamat, Thomas Michael Seigler, Jesse B. Hoagg Jan 2026

Electromagnetic Formation Flying Using Alternating Magnetic Field Forces And Control Barrier Functions For State And Input Constraints, Sumit Suryakant Kamat, Thomas Michael Seigler, Jesse B. Hoagg

Mechanical Engineering Faculty Publications

This article presents a feedback control algorithm for electromagnetic formation flying with constraints on the satellites’ states and control inputs. The algorithm combines several key techniques. First, we use alternating magnetic field forces to decouple the electromagnetic forces between each pair of satellites in the formation. Each satellite’s electromagnetic actuation system is driven by a sum of amplitude-modulated sinusoids, where amplitudes are controlled in order to prescribe the time-averaged force between each pair of satellites. Next, the desired time-averaged force is computed from an optimal control that satisfies state constraints (i.e., no collisions and an upper limit on intersatellite speeds) …


Protocol For Stable Isotope Tracing Of Primary Human Peripheral Blood Mononuclear Cells, Samantha N. Hart, Holden C. Williams, William B. Inabnet Iii, Joshua P. Steiner, Varun Jain, Philip A. Kern, Cecily R. Wood, Barbara S. Nikolajczyk, Lance A. Johnson Jan 2026

Protocol For Stable Isotope Tracing Of Primary Human Peripheral Blood Mononuclear Cells, Samantha N. Hart, Holden C. Williams, William B. Inabnet Iii, Joshua P. Steiner, Varun Jain, Philip A. Kern, Cecily R. Wood, Barbara S. Nikolajczyk, Lance A. Johnson

Molecular and Cellular Biochemistry Faculty Publications

Stable isotope tracing gives direct insight into the rate of metabolic reactions occurring in cells by analyzing the incorporation of labeled carbons into metabolic pathways. Here, we present a protocol for stable isotope tracing of primary human peripheral blood mononuclear cells (PBMCs). We describe the steps for culturing and exposing PBMCs to stable isotopes U13C glucose and U13C glutamine. We then detail procedures for derivatization, metabolite purification, and tracing analysis via single-quadrupole gas chromatography-mass spectrometry (GC-MS).


Leadership And Creative Placemaking In Central Appalachia: Morehead, Kentucky, Toni C. Hobbs Jan 2026

Leadership And Creative Placemaking In Central Appalachia: Morehead, Kentucky, Toni C. Hobbs

Theses and Dissertations--Arts Administration

In rural Appalachia, longstanding patterns of extractive economic development, coupled with limited public investment and uneven institutional support, have contributed to persistent economic stagnation and a diminished sense of pride among residents. These conditions reflect deeper structural challenges, including economies shaped by resource extraction and external control. Addressing these conditions is critical to fostering economic growth, promoting cultural heritage, and enhancing overall well-being in the region. By cultivating resilient communities, leaders can create environments in which both the economy and local pride can thrive, contributing to a more prosperous and unified Appalachian region.

This study investigates the organizational and leadership …


Deep Learning-Based Quantification Of Tall Fescue Abundance In Pastures, Rose E. Binkley, Samuel R. Revolinski, Echo Elizabeth Gotsick, Ray Smith, Zeya Wang, Katsutoshi Mizuta Jan 2026

Deep Learning-Based Quantification Of Tall Fescue Abundance In Pastures, Rose E. Binkley, Samuel R. Revolinski, Echo Elizabeth Gotsick, Ray Smith, Zeya Wang, Katsutoshi Mizuta

Plant and Soil Sciences Faculty Publications

Accurate and rapid measurement of tall fescue abundance is essential for efficient forage management and mitigating livestock exposure to potential endophyte-related toxicity. Traditional visual estimation methods are labor-intensive and are subject to change depending on the observer doing the calculations, which limits their scalability and consistency. This study explores the application of deep learning techniques to automate and improve the classification of tall fescue abundance across pasture systems in Kentucky. Ground-truth abundance classes were evaluated using one of the traditional methods with occupancy grid and compared against estimates derived from red-green-blue images. Two convolutional neural network architectures, YouOnlyLookOnce (YOLO) and …


Driving Employee Engagement Across Sectors: Current Evidence And An Agenda For Future Research, Taha Hameduddin, Kerstin Alfes, Adrian Ritz Jan 2026

Driving Employee Engagement Across Sectors: Current Evidence And An Agenda For Future Research, Taha Hameduddin, Kerstin Alfes, Adrian Ritz

Public Policy and Administration Faculty Publications

Employee engagement has emerged as a critical employee attitude linked to employee motivation and organisational performance and has successfully embedded itself in governments around the world. Apart from a few exceptions, however, much of what we know about engagement does not attend to the institutional context of public institutions and whether private-sector theories and approaches to driving employee engagement work well in public sector organisations. To address this gap, we systematically review the evidence on antecedents of employee engagement, and determine whether and how sectoral differences may matter. We then discuss the findings and contextualise the debate surrounding the employee …


The Association Between Personal Particulate Matter Exposures And Cognitive Function Among Stroke Patients, Kentucky, Usa, Nana Afua Ankomah Dei Jan 2026

The Association Between Personal Particulate Matter Exposures And Cognitive Function Among Stroke Patients, Kentucky, Usa, Nana Afua Ankomah Dei

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Stroke, a major cause of long-term disability and cognitive problems in the U.S., significantly affects people’s quality of life. Exposure to particulate matter (PM2.5) may result in systemic inflammation and oxidative stress, which can worsen the cognitive function of post-thrombectomy stroke patients. This project thus assessed the relationship between PM2.5 exposure and its effect on the cognitive function of post-thrombectomy stroke patients. Fifteen stroke patients (9 non-Appalachian and 6 Appalachian) undergone thrombectomy were recruited. Personal PM2.5 exposure was measured using wearable sensors for a week during the study period. Montreal Cognitive Assessment (MoCA) scores and covariates …


Teachers, Dispositions, And Classroom Management: Social Origins, Professional Development, And The Datafication Of School Discipline, Paul L. Poggemeyer Jan 2026

Teachers, Dispositions, And Classroom Management: Social Origins, Professional Development, And The Datafication Of School Discipline, Paul L. Poggemeyer

Theses and Dissertations--Sociology

How do teachers’ social backgrounds and professional orientations shape the disciplinary and relational dimensions of their work? This dissertation takes up that question across three related but self-contained studies in the sociology of education, set in Central School District, a public school district in the southeastern United States. Each study examines a different facet of how teachers establish authority, manage behavior, and exercise care: the social origins of their orientations toward classroom management, the experience of becoming professionally competent in the early career, and the use of digital tools that increasingly govern how school discipline is recorded. Drawing broadly on …