Digital Commons Network^™

The Critical Need For Early Language Access For Deaf And Hard Of Hearing Children, Kinya D. Embry-Wright

Theses and Dissertations--Rehabilitation Sciences

According to the American Speech-Language-Hearing Association (ASHA), speech-language pathologists (SLPs) are referred to as the experts of communication (ASHA, n.d.) utilizing their specialized training, extensive education, and clinical expertise to work with individuals across the lifespan with a variety of different speech and language delays, disorders, and deficits. However, when working with deaf or hard of hearing (DHH) children, there is often precedent given to speech and listening (M. L. Hall et al., 2019). For example, ASHA only recently updated their DHH portal to include American Sign Language (ASL), though they still list it on some webpages as an Augmentative …

Malleability Of Abortion Attitudes, Allison Leip

Theses and Dissertations--Family Sciences

Although abortion attitudes have been thoroughly investigated and population-level attitudes have not changed much over the past half-century, polls and research inquiring about abortion attitudes tend to ask isolated questions about if, and in what circumstances, abortion should be legal. The purpose of this study was to examine the extent to which abortion attitudes both varied and changed according to several contextual factors. A multiple-segment factorial vignette was conducted with 530 respondents in the state of Kentucky. Overall, most respondents held strong attitudes on access to abortion, both before the rationale was provided and regardless of the rationale provided. However, …

Sex Differences In Pediatric Hypertension: Obesity, Stress, And The Renin-Angiotensin System, Allyson Dyar

Theses and Dissertations--Nutrition and Food Systems

Pediatric hypertension, linked to long-term cardiovascular risks, shows increasing prevalence and varying patterns between boys and girls. This study explores sex-based differences in hypertension among 251 children aged 6-18 from Kentucky Children’s Hospital. Using 24-hour ambulatory blood pressure monitoring (ABPM) and assessing plasma renin, aldosterone, and cortisol, we examined blood pressure severity by sex. Girls showed a higher incidence of severe hypertension and elevated cortisol levels, whereas boys had higher mean systolic blood pressure. Aldosterone was associated with night systolic blood pressure in girls, while night diastolic blood pressure was linked to aldosterone in both sexes and renin in girls. …

The Relationships Between Maternal And Paternal Inconsistent Parenting And Cyberbullying Victimization, Anxiety And Depressive Symptoms Among Adolescents, Lynn Maamari

Theses and Dissertations--Family Sciences

The present research investigated the associations between maternal and paternal inconsistent parenting and cyberbullying victimization, anxiety, and depression. It also tested the extent to which these relationships were moderated by sex. It was expected that inconsistent maternal and paternal parenting would be positively associated with cyberbullying victimization, anxiety, and depressive symptoms. It was also expected that the links between maternal and paternal inconsistent parenting and cyberbullying victimization, anxiety as well as depression symptoms would not be moderated by sex. Data were collected from 500 14–18-year-old Czech teenagers, with a mean age of 14.4 years; 54% of the participants were female. …

Examining The Feasibility Of Implementing Farm To School Programs In Rural Kentucky Schools: Barriers And Successes Of Initiating Programming As Identified Through Teacher’S Observations, Christina Wilson

Theses and Dissertations--Nutrition and Food Systems

Farm to School (FTS) programs provide experiential learning opportunities to children that have the potential to shape eating patterns and, in turn, improve health and learning outcomes. Participation in FTS programs in Kentucky is growing. However, programming varies widely across schools, and few have an edible school garden. This study examined the feasibility of establishing an edible school garden while incorporating FTS programming by evaluating teachers' observations and experiences. Six rural Kentucky schools were selected to receive a $5,000 grant to initiate an edible school garden and incorporate FTS programming. A Qualtrics survey measured six categories regarding implementation. The results …

Current And New Perspectives On Equine Protozoal Myeloencephalitis Therapeutics, Izabela De Assis Rocha

Theses and Dissertations--Veterinary Science

Equine protozoal myeloencephalitis (EPM) is an important neurologic disease of horses in the Americas. It is caused by the apicomplexan parasite Sarcocystis neurona and less commonly by the related parasite Neospora hughesi. Current antiprotozoal treatment relies on the use of either folate inhibitors (sulfadiazine/pyrimethamine) or triazine drugs (diclazuril/ponazuril), with a success rate of 60-70% regardless of the drug of choice. Successful treatment is defined as the improvement of at least one ataxia grade following the modified Mayhew scale, which often is not enough for the horse to return to the previous level of performance. The goals of this dissertation …

Determining Population Structure In Kentucky Parascaris Univalens Specimens, Constance Finnerty

Theses and Dissertations--Veterinary Science

Parascaris univalens is a highly pathogenic nematode that affects the gastrointestinal system of young horses. When unaddressed, this parasite causes severe intestinal impactions and even death. Parascaris univalens is also found to have an emergence of anthelmintic resistances, causing a concern for horse owners. Despite its clinical significance, very little work has been done on Parascaris univalens to identify its population structure. This study aimed to determine the population structure of Parascaris univalens through Illumina next generation sequencing (NGS) on three hierarchical categorizations: within a horse, within an isolated herd, and within horses in the state of Kentucky. A total …

Communicating Climate Change: Adaptive Silviculture In Central Appalachian Kentucky, Logan Baker

Theses and Dissertations--Forestry and Natural Resources

Climate change communication is an emerging field that requires a multidisciplinary understanding of both climate and social science. Communicating with underrepresented woodland owners about climate change, specifically climate change adaptation in forestry applications, necessitates appropriately adjusted approaches. In Central Appalachian Kentucky, outreach with underrepresented woodland owners on forest adaptation topics has not been examined in depth. The recent establishment of an Adaptive Silviculture for Climate Change research site in the University of Kentucky’s Robinson Forest has created an opportunity to generate regionally specific climate adaptation information for Appalachian Kentucky forests. It is imperative to investigate how best to approach communicating …

Exploring The Impact Of An Appalachian Higher Education Institution Had On Fostering Solidarity, Capacity, And Agency Of Female Appalachian Students Seeking To Positively Influence The Quality Of Life For Themselves And Appalachian Communities, Analiese Mitchell

Theses and Dissertations--Community & Leadership Development

Appalachian women navigating higher education encounter multifaceted challenges, often confronting marginalization and a lack of representation within academic spaces. This study investigates the experiences of female Appalachian students at Mountain University in Kentucky, aiming to shed light on their journey and the university's impact on their lives and communities. Drawing on qualitative data from interviews, the research explores themes of solidarity, capacity, agency, and Quality of Life. Findings reveal a robust sense of solidarity among Appalachian peers and faculty, fostering a supportive environment conducive to personal and academic growth. Participants express opportunities to engage with their communities positively, contributing to …

Development Of Lignin Derived Hydrophobic Deep Eutectic Solvents As Sustainable Solvents And Their Applications, Yuxuan Zhang

Theses and Dissertations--Biosystems and Agricultural Engineering

The development of green solvents is a pivotal endeavor in achieving the goals of green chemistry. Ionic liquids (ILs) and deep eutectic solvents (DESs) have emerged as promising green alternatives to conventional organic solvents due to their low toxicity, potential biodegradability, low volatility, and high tunability. Compared to ILs, DESs have attracted more attention recently as they are easier and less expensive to produce. Hydrophobic DESs (HDESs), a new generation of DESs introduced in 2015, have gained considerable interest for their ability to overcome the instability issues of traditional DESs when exposed to water. This advancement extensively broadens the application …

The Characterization, Assessment, And Shear Strength Of Turfgrass Soil In North American Thoroughbred Racing, Peter Schmitt

Theses and Dissertations--Biosystems and Agricultural Engineering

Minimizing catastrophic injuries to racehorses, which also protects the riders, is critical for the future of the Thoroughbred racing industry. While the causes of catastrophic injuries are multifactorial, the condition of the racing surface is one of only a few factors that affects all horses in competition. Horse racing surfaces must retain enough shear strength to support the hoof of a Thoroughbred at a gallop. Turfgrass racing surfaces also require healthy turf to reinforce the footing while also achieving a high infiltration rate to allow races to run on the turf soon after or even during rain. This research is …

The Efficacy Of Wetland Treatment Systems Used To Treat Runoff Mixtures From Different Landscapes Across Kentucky, Emily Nottingham

Theses and Dissertations--Biosystems and Agricultural Engineering

The overarching goal was to improve our understanding of the cumulative effect of increased use and occurrence of commonly detected contaminants of potential concern (CPCs) on nitrogen (N) transformation processes in wetlands. The central hypothesis was that those various mixtures of nutrients and CPCs entering treatment wetlands impact N removal pathways. The first study assessed the current state of the literature on the implications to N removal in wetlands in the presence of pesticides and antibiotics. 181 primary studies were identified. Removal efficiencies for nitrate varied widely across the studies, with CPCs impacting microbial communities. A knowledge gap remains in …

Improving Healthcare Provider Knowledge And Confidence With Treating The Lgbtq Population Through A Web-Based Education Module, Logan Price

DNP Projects

Background: There is a need for improved healthcare staff and provider knowledge and confidence when treating the LGBTQ population, as many healthcare providers are insufficiently prepared to treat LGBTQ patients (Rowe et al., 2017). This population is at greater risk for mental illness, substance use, and physical illness than the general population due to societal factors such as minority stress and stigma (Cochran et al., 2004; Cochran & Mays 2007; Cochran et al., 2003; Meyer, 2003). Purpose: The purpose of this project is to educate healthcare staff and providers about the LGBTQ population to improve their knowledge and confidence when …

Point Of Care Ultrasound (Pocus) For Advanced Practice Providers (Apps), Crystal S. Rogers

DNP Projects

Background: Advanced practice providers (APPs) routinely lack the skillset to perform Point of Care Ultrasound (POCUS) because currently, there is not a standardized curriculum within scholarly programs (Santos et al., 2018) and/or inadequate hospital training to perform these competencies (Huang et al., 2021). The absence of a standard curriculum has limited the ability of APPs to practice with full scope, provide care that is comparable to physician partners in the acute care setting, and deliver highest quality of patient care. Implementing standard education to train APPs for POCUS addresses this identified gap.

Purpose: The purpose of this project was to …

The Effects Of Stigma Within The Prep Care Cascade Among People Who Inject Drugs In Rural Kentucky, Abby Burton

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: Injection drug use has increased HIV burden in low-prevalence communities, specifically within rural Kentucky. Pre-exposure prophylaxis (PrEP) has been successful in terms of HIV prevention, yet uptake remains low among people who inject drugs (PWID). PWID living in rural areas face unique challenges to receiving PrEP care, including significant barriers of substance use- and HIV-related stigma. Recent studies have only started to explore the overlapping effects of these two stigmas. Considering the barriers each stigma independently poses to PrEP care, it is important to investigate their role in tandem for any compounding effects. This paper is a secondary analysis …

A Case Study In Program Evaluation, Lydia Williams

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The three core functions of public health are assessment, policy development, and assurance, and program evaluation falls under the latter category. A program is incomplete without an in-depth understanding of how well it works and what steps can be taken to make sure there is continuous progress and improvement.

In this case study, I developed an evaluation plan for the Lexington-Fayette County Health Department’s (LFCHD) infectious disease outbreak education program. The need for such a program was realized after a MRSA outbreak among a Kentucky high school football team. This case study employed the Center for Disease Control and Prevention …

Combined Motivational Interviewing And Ecological Momentary Intervention To Reduce Hazardous Alcohol Use Among Sexual Minority Cisgender Men And Transgender Individuals, Carolyn Lauckner, Bryce Puesta Takenaka, Fidelis Sesenu, Jaime S. Brown, Sally J. Kirklewski, Erin Nicholson, Kimberly Haney, Reuben Adatorwovor, Donte T. Boyd, Keisa Fallin-Bennett, Arjee Javellana Restar, Trace Kershaw

Biostatistics Faculty Publications

Background: Sexual minority cisgender men and transgender (SMMT) individuals, particularly emerging adults (aged 18-34 years), often report hazardous drinking. Given that alcohol use increases the likelihood of HIV risk behaviors, and HIV disproportionately affects SMMT individuals, there is a need to test interventions that reduce hazardous alcohol use and subsequent HIV risk behaviors among this population. Ecological momentary interventions (EMIs), which use mobile phones to deliver risk reduction messages based on current location and behaviors, can help to address triggers that lead to drinking in real time. Objective: This study will test an EMI that uses motivational interviewing (MI), smartphone …

Stigma And Efficacy Beliefs Regarding Opioid Use Disorder Treatment And Naloxone In Communities Participating In The Healing Communities Study Intervention, Nicky Lewis, Barry Eggleston, Redonna K. Chandler, Dawn Goddard-Eckrich, Jamie E. Luster, Dacia Beard, Emma Rodgers, Rouba A. Chahine, Philip M. Westgate, Shoshana N. Benjamin, Janae Holloway, Thomas Clarke, R. Craig Lefebvre, Michael D. Stein, Donald W. Helme, Jennifer Reynolds, Sharon L. Walsh, Darcy Freedman, Nabila El-Bassel, Kara Stephens, Anita Silwal, Michelle R. Lofwall, Janet E. Childerhose, Hilary L. Surratt, Brooke N. Crockett, Amy L. Farmer, James L. David, Laura Fanucchi, Judy Harness, Ben Wilburn, Kelli Bursey, Kristin Mattson, Sarah Mann, Rebecca D. Jackson, Aimee Shadwick, Katherine Calver, Deborah Chassler, Jennifer Kimball, Nancy Regan, Jeffrey H. Samet, Rachel Sword-Cruz, Michael D. Slater

Biostatistics Faculty Publications

Background The HEALing Communities Study (HCS) included health campaigns as part of a community-engaged intervention to reduce opioid-related overdose deaths in 67 highly impacted communities across Kentucky, Massachusetts, New York, and Ohio. Five campaigns were developed with community input to provide information on opioid use disorder (OUD) and overdose prevention, reduce stigma, and build demand for evidence-based practices (EBPs). An evaluation examined the recognition of campaign messages about naloxone and whether stigma and efficacy beliefs regarding OUD treatment and naloxone changed in HCS intervention communities.

Methods Data were collected through surveys offered on Facebook/Instagram to members of communities participating in …

Development Of Fungal Hydrogels For 3d Bioprinting And Cellular Agriculture, Lauren E. Doyle

Theses and Dissertations--Biosystems and Agricultural Engineering

Hydrogel scaffolds are an important component to cellular agriculture. There is a need for a sustainable alternative to the commonly used gelatin-sodium-alginate hydrogels. Specific edible fungus species may provide a suitable alternative. Many fungi possess high protein contents, ease of cultivation, and strong functional properties. However, functional characterizations and application of fungal flour and protein extracts in cellular agriculture are lacking in the literature. Therefore, this study’s objectives were to 1) Develop processes to create functional fungal protein fractions from different fungal strains and evaluate their characteristics, and 2) Quantify the printability of the resulting fungal gels for the creation …

Caught In The Crosshairs Of Educational Reform: How Teacher Labor Markets Respond To Polarized Education Policies, Danielle Duffy Chipman

Theses and Dissertations--Public Policy and Administration

Since the passage of No Child Left Behind (NCLB) teachers have been caught in the crosshairs of political debates about education policy (Davis, 2014; EPE Research Center, 2013a; Steiner & Woo, 2021; Woo et al., 2022; Zubrzycki, 2016). As political polarization between parties increased in the 2000s, debates about education policy became more acrimonious impacting teachers’ work lives (Heltzel & Laurin, 2020; Iyengar, 2021; Layman et al., 2006). The topic of these debates ranges from curriculum changes such as Common Core and Critical Race Theory (CTR), school shootings and safety, battles over school choice and voucher programs, teacher activism about …

Extracting Social Network Model Parameters From Social Science Literature, Isaac Batts

Theses and Dissertations--Computer Science

When looking at computer modeling of social situations, much of the social science literature does not include ready-to-use statistics or parameters to be included in a social model. I explore studies related to speaking about racism (and other forms of bias), and interventions designed to diminish the occurrence of biased behavior, and use those readings to synthesize plausible parameters for a social computer model.

Inflammation And Tumor Progression: The Differential Impact Of Saa In Breast Cancer Models, Daniel Wilhelm Olivier, Carla Eksteen, Manisha Du Plessis, Louis De Jager, Lize Engelbrecht, Nathaniel Wade Mcgregor, Preetha Shridas, Frederick C. De Beer, Willem J. S. De Villiers, Etheresia Pretorius, Anna-Mart Engelbrecht

Saha Cardiovascular Research Center Faculty Publications

Background: Previous research has shown that the Serum Amyloid A (SAA) protein family is intricately involved in inflammatory signaling and various disease pathologies. We have previously demonstrated that SAA is associated with increased colitis disease severity and the promotion of tumorigenesis. However, the specific role of SAA proteins in breast cancer pathology remains unclear. Therefore, we investigated the role of systemic SAA1 and SAA2 (SAA1/2) in a triple-negative breast cancer mouse model.

Methods: Syngeneic breast tumors were established in wild-type mice, and mice lacking the SAA1/2 (SAADKO). Subsequently, tumor volume was monitored, species survival determined, the inflammatory profiles of mice …

The Integrated Behavioral Model Of Mental Health Help Seeking (Ibm-Hs): A Health Services Utilization Theory Of Planned Behavior For Accessing Care, Joseph H. Hammer, David L. Vogel, Patrick R. Grzanka, Nayeon Kim, Brian T. Keum, Claire Adams, Sarah A. Wilson

Chemical and Materials Engineering Faculty Publications

This article introduces the integrated behavioral model of mental health help seeking (IBM-HS), a theoretical model for understanding the constructs (e.g., systemic, predisposing, and enabling factors; mental health literacy; illness perceptions; perceived need; stigma; shame; perceived benefits, motivation) that influence people’s decision making around seeking professional mental health care and their ultimate access to formal treatment. The IBM-HS is a help-seeking-specific adaptation of the empirically supported integrated behavioral model and integrative model, which are themselves evolutions of the theory of planned behavior and theory of reasoned action. The IBM-HS posits that help-seeking determinants (e.g., structural forces; cultural influences; past help-seeking …

Disorganization Of Actin Within The Shafts Of Stereocilia Is A Key Difference Between Temporary And Permanent Noise-Induced Hearing Loss (Nihl), Shadan Hadi

Theses and Dissertations--Physiology

During sound stimulation, mechanosensory stereocilia of the auditory hair cell pivot around their bases, where their actin cores become denser and form rootlets protruding into the cuticular plate. It is believed that actin-based cuticular plate provides a stable mechanical support for stereocilia, while rootles are responsible for their pivotal flexibility and life-long resilience to mechanical stimuli. Not surprisingly, damage to the stereocilia bundles is known as a hallmark of permanent noise-induced hearing loss (NIHL). Yet, despite decades of NIHL studies, it is still unknown which ultrastructural changes in the stereocilia bundles are evoked directly by mechanical overstimulation.

Here, we explored …

The Impact Of Measure 110 On Fatal Overdoses, Property And Violent Crime In Oregon, Hannah Mercado

MPA/MPP/MPFM Capstone Projects

In November 2020, the Drug Addiction Treatment and Recovery Act (also known as Measure 110) was passed in Oregon with the purpose to provide access to treatment and recovery services available to anyone who may need to utilize them, while focusing on a health-oriented approach towards substance use disorder (SUD) across the state through the removal of low-level drug possession criminal penalties (Oregon Health Authority, n.d.). Historically, Oregon has consistently had some of the highest rates of substance use in the U.S., making this a pertinent issue which was addressed through the implementation of Measure 110. Citing a critical need …

Government Grant Receipts And Revenue Volatility: A Correlational Investigation Of Medium-Sized Arts Organizations, Carly Colvin

MPA/MPP/MPFM Capstone Projects

Minimal revenue volatility has been shown to enable more accurate planning by nonprofit managers and contribute to nonprofit financial sustainability. The volatility of government revenues, a major income source for nonprofit organizations, is not a well-researched topic. This capstone presents correlational tests to study the relationship between government grant receipts and revenue volatility within medium-sized nonprofit arts organizations in California. In addition, a data compilation methodology is tested and documented to enable future research. The results do not show a correlation between receipt of government grants and revenue volatility. The ensuing considerations for nonprofit managers along with areas for future …

University Of Kentucky Healthcare Community Engagement Program Strategic Plan, Madison Fyffe

MPA/MPP/MPFM Capstone Projects

Strategic planning is an essential tool in providing direction to an organization through analysis of its current state and ideal future, and development of strategic goals. The University of Kentucky HealthCare’s community engagement program is a robust program within the department of Brand Strategy, tasked with serving all 120 Kentucky counties and over 150 local, state, and national organizations through health education, event sponsorship, and promotional resources. In its current state, a strategic plan to guide and track performance does not exist. This capstone aims to develop a strategic plan through the assessment of strategic planning theory, stakeholder analysis, and …

Employer Incentivized Cancer Screenings In Kentucky: A Case Study, Addison Dumes, Sophia Freeman, Megan Latiff

MPA/MPP/MPFM Capstone Projects

Kentucky has some of the highest mortality rates for colon, breast, cervical and lung cancer in the United States, according to the Center of Disease Control. Our Client, The Foundation for a Healthy Kentucky, is seeking to lower these rates by increasing employer driven cancer screenings. Previous studies show many states have been successful in implementing programs to motivate employees to participate in preventative screenings. Through individual interviews with Kentucky employers, this study aims to answer what factors affect the best practices and perceived barriers amongst employers with health and wellness programs to increase the rate of preventative breast, cervical, …

Impact Of The Availability And Affordability Of Childcare On The Economy, Valentina Osunmade, Cameron French

MPA/MPP/MPFM Capstone Projects

Kentucky's workforce participation rates are among the lowest in the nation, thus underscoring the urgent need to strengthen and sustain its workforce (Aull, 2023). One significant barrier for many families in the workforce is the lack of accessibility and affordability of childcare. The Child Care Assistance Program (CCAP) in Kentucky aims to alleviate this burden for low-income families. Despite the program's importance, no prior study has examined the direct impact of CCAP enrollment on workforce participation in Kentucky. This research addresses this gap by conducting a multiple regression analysis using aggregate data from the Kentucky Center for Statistics, the US …

Lexington Black Prosperity Initiative: Addressing Lexington’S Equity Gap, Kinsleigh Smith, Jason Schubert

MPA/MPP/MPFM Capstone Projects

The equity gap between Black Americans and white Americans is a persistent social issue. This equity gap presents itself in a variety of measures – wealth accumulation, homeownership, healthcare, educational achievement, financial stability, and more. Locally, the Lexington Black Prosperity Initiative, a program of the Blue Grass Community Foundation, is primarily focused on strengthening Lexington’s Black community and closing this equity gap. The initiative was established in 2020. As the Lexington Black Prosperity Initiative enters its fourth year of operations, they are seeking to expand their reach within the community by enacting long-lasting and sustainable programs that will work to …