Digital Commons Network^™

The Effects Of Stimulant Medication On The Online Story Narrations Of Children With Adhd, Karen J. Derefinko, Ursula L. Bailey, Richard Milich, Elizabeth P. Lorch, Elizabeth Riley

Psychology Faculty Publications

The current study investigated the inclusion of goal-based story events in the online story narrations of children with ADHD, as compared with their peers, and explored the effect of stimulant medication on the narrations in children with ADHD. Children completed a narration task on two separate occasions. Children with ADHD (n = 17) completed one narration on medication and the other one on placebo. Results indicated that narrations of comparison children (n= 25) were significantly more likely than narrations of children with ADHD to include the story’s positive outcome, completion of the story’s overall goal, and specific …

The Relative Effect Of Alternative Regulatory Actions: Benchmarks For The Compliance And Discipline Process In Different Jurisdictions And Occupations, Robert J. Mcatee

MPA/MPP/MPFM Capstone Projects

The compliance processes of many regulatory agencies have recently come under close scrutiny. The media have portrayed the compliance and discipline processes of many regulatory agencies as being inefficient and not timely in many instances. The Council of Licensure, Enforcement, and Regulation (CLEAR) intends to assist regulatory agencies to do their work in a more efficient and timely manner by providing them with adequate and helpful information.

In the spirit of CLEAR’s mission, a collaborative effort was embarked upon by CLEAR staff and leadership, professionals with experience in the compliance and discipline process along with myself to produce a survey …

A Confused Concern Of The First Amendment: The Uncertain Status Of Constitutional Protection For Individual Academic Freedom, Neal H. Hutchens

Educational Policy Studies and Evaluation Faculty Publications

The question of whether the First Amendment protects the individual academic freedom of faculty members at public colleges and universities has resulted in divergent views among courts and legal scholars. In joining the ongoing discourse regarding constitutional protection for academic freedom, this article considers using academic freedom policies and standards voluntarily adopted by institutions as a basis to provide First Amendment protection for faculty speech at public colleges and universities. The article proposes that such policies present one alternative to help clear some of the legal fog regarding First Amendment protection for individual academic freedom, especially in relation to the …

Cell Phones Pose A Distraction To Drivers But Legislative Ban Is Not The Answer, Annie Barret Wallin

Kentucky Law Journal

No abstract provided.

Widespread Panic: Why The Mortgage Lending Industry Can Calm Down About Amending Cramdown, David T. Newton

Kentucky Law Journal

No abstract provided.

Pathways For Synthesis, And Possibilities For Genetic Modification Of Sugar Ester Acyl Groups Produced By Trichomes Of Solanaceous Species, Antoaneta B. Kroumova, George J. Wagner

Plant and Soil Sciences Faculty Publications

Glandular trichomes of many plant species synthesize and secrete a variety of phytochemicals that play an important protective role against pathogens and pests. Acyl sugars, in particular, are powerful natural insecticides. We demonstrated the existence of the α-ketoacid elongation (αKAE) pathway, an alternative to the fatty acid synthase (FAS) pathway, for the extension of carbon chains of acyl groups in sugar esters (SE). The α-KAE pathway utilizes one carbon elongation per cycle in contrast to two carbons per cycle in FAS, and it was found to function in a variety of tobaccos and petunia. FAS-mediated elongation was confirmed to participate …

Glutamate Regulation In The Hippocampal Trisynaptic Pathway In Aging And Status Epilepticus, Michelle Lee Stephens

University of Kentucky Doctoral Dissertations

A positive correlation exists between increasing age and the incidence of hippocampal-associated dysfunction and disease. Normal L-glutamate neurotransmission is absolutely critical for hippocampal function, while abnormal glutamate neurotransmission has been implicated in many neurodegenerative diseases. Previous studies, overwhelmingly utilizing ex vivo methods, have filled the literature with contradicting reports about hippocampal glutamate regulation during aging. For our studies, enzyme-based ceramic microelectrode arrays (MEA) were used for rapid (2 Hz) measurements of extracellular glutamate in the hippocampal trisynaptic pathway of young (3-6 months), late-middle aged (18 mo.) and aged (24 mo.) urethane-anesthetized Fischer 344 rats. Compared to young animals, glutamate terminals …

The Impact Of Perceived Barriers To Export: An Analysis Of Kentucky Agricultural And Food Processing Firms, Kelly A. Davidson

University of Kentucky Master's Theses

As intra-industry trade increases in U.S. agricultural and food processing industries, the historical agricultural trade surplus is tightening. In efforts to maintain the trade surplus a focus has shifted towards the promotion of agricultural and processed food exports among small and medium sized firms. This study intends to identify and evaluate the potential for exports among small to medium sized agricultural and food processing firms in Kentucky through a collection of survey data. The objectives of this thesis are to identify the state’s product marketing opportunities and product specifications for international exports while identifying transaction requirements for potential exports. An …

Tunable Laser Interrogation Of Surface Plasmon Resonance Sensors, Vaibhav Badjatya

University of Kentucky Master's Theses

Surface plasmons are bound TM polarized electromagnetic waves that propagate along the interface of two materials with real dielectric constants of opposite signs. Surface plasmon resonance (SPR) sensors make use of the surface plasmon waves to detect refractive index changes occurring near this interface. For sensing purposes, this interface typically consists of a metal layer, usually gold or silver, and a liquid dielectric. SPR sensors usually measure the shift in resonance wavelength or resonance angle due to index changes adjacent to the metal layer. However this restricts the limit of detection (LOD), as the regions of low slope (intensity vs. …

An Interaction Between Risk Perceptipton And Trust In Response To Food Safety Events Across Products And Regions, And Their Implicaitons For Agribusiness Firms, Jonathan D. Shepherd

University of Kentucky Master's Theses

Food safety events receive substantial media coverage and can create devastating economics losses for agribusiness firms. It is unclear what factors influence consumers’ purchasing decisions before or after a food safety event occurs. The objectives of this study is to identify these factors that influence purchasing decisions, determine how consumers respond to hypothetical food safety events, and compare these findings across different products and geographical regions. The data for this research was obtained from two surveys. One survey concerned fresh produce while the second focused on meat products. The SPARTA model, based on the Theory of Planned Behavior, is used …

In My Humble Opinion: Testing The Sprial Of Silence In Computer-Mediated And Face-To-Face Contexts, Robert James Zuercher

University of Kentucky Master's Theses

The purpose of this investigation is to further an understanding of the spiral of silence theory as it functions within both face-to-face (FtF) and computer-mediated contexts. Computer-mediated communication (CMC is often touted for being an empowering medium as it affords its users anonymity. This finding could have an impact on whether the spiral of silence occurs within CMC. Previous studies have relied upon hypothetical scenarios and have established weak support for the theory. Despite this study’s utilization of a within-subjects experimental design, however, no significant differences in minority opinion holders’ fear of isolation were found. Similarly, no significant relationship was …

The Impact Of Interactive Functionality On Learning Outcomes: An Application Of Outcome Interactivity Theory, James P. Gleason

University of Kentucky Doctoral Dissertations

Scholars have examined a variety of dimensions and models of interactivity in an attempt to articulate a comprehensive definition. Outcome Interactivity Theory (OIT) considers interactivity to be the result of a communication event involving the successful integration of three predictive dimensions: the presence of actual interactive technological features, the presence of similarly reactive content elements, and relevant user experiences that empower the user to employ these interactive elements within the communication event toward a desirable outcome.

This dissertation accomplishes three major objectives: clarify the literature relating to the interactivity construct; introduce Outcome Interactivity Theory as a new theory-based conceptualization …

Biology And Management Of The Bed Bug, Cimex Lectularius L. (Heteroptera: Cimicidae), Alvaro Romero

University of Kentucky Doctoral Dissertations

The near absence of bed bugs from human dwellings for fifty or more years has left us with limited knowledge of its biology and few answers to eliminate populations. I explored a diverse set of objectives to answer key questions concerning bed bug biology and control. Major objectives were studies of circadian rhythmicity, pyrethroid resistance, sublethal effects of insecticides, synergism of pyrethroids, and evaluation of a pyrrole insecticides, chlorfenapyr. Additional studies included persistence of Borrelia in bed bugs after ingestion, and aggregation factors from feces.

In the absence of host stimuli, insects were much more active in the dark than …

The Distribution Of Unpaired During Drosophila Oogenesis, Travis Sexton

University of Kentucky Doctoral Dissertations

Janus Kinase (JAK) activity specifies the cell fates of the follicular epithelium during Drosophila oogenesis by establishing a gradient of JAK activity with highest levels at the A/P poles. Unpaired (Upd), a ligand for the pathway, is expressed and secreted exclusively from the polar cells potentially establishing the JAK activity gradient. This project proposed that Upd acts as a morphogen to directly establish the JAK activity gradient, specifying the fates of the follicular epithelium. The aims of this work were to investigate the extracellular distribution of Upd and, in addition, factors that may be involved. Furthermore, upd3, a gene …

Role Of Aryl Hydrocarbon Receptor In Chronic Inflammatory Diseases, Violeta Arsenescu

University of Kentucky Doctoral Dissertations

Aryl Hydrocarbon Receptor (AhR) is a ligand-actviated receptor known as the dioxin receptor. Environmental pollutants called dioxin-like toxicants are found in food, cigarette smoke, automobile exhaust and air. Therefore, they could chronically amplify the pathology of numerous chronic inflammatory diseases. AhR is a well known target of these environmental chemicals that disrupt endocrine signaling. By the year 2020, the number of people older than 60 years is expected to top 1 billion. The burden of treating chronic disease is significant both in dollars spent and in lost productivity. The need to identify risk factors for chronic diseases must be evaluated …

Protesting Liberalization In India: An Examination Of Discursive Strategies Used By Street-Vendors, Squatters, And Small-Retailers To Create And Universalize Resistance Narratives, Rajesh Gaur

University of Kentucky Doctoral Dissertations

The retail sector in India is experiencing a shift from an industry dominated by small grocers serving the needs of local markets to one characterized by chain retailers, both national and international. The liberalization of the retail sector in the last decade has edged the street-vendors, squatters, and small retailers from the prime business spaces to marginalized peripheries, which had led to widespread localized protests by the small retailers all over the country.

The Aminabad Market in a metro city in northern India provided a unique opportunity to study ongoing resistance against chain retailing. The retailers of Aminabad were at …

Content Relevance Centric Theory: An Investigation Of Content Relevance's Ability To Predict Learning Outcomes In A Training Environment, E. Patrick Leddin

University of Kentucky Doctoral Dissertations

After three decades of research, instructional communication scholars find themselves facing several key challenges. These range from an overemphasis in past studies on variable-analytic, atheoretical research to a lack of connection to learning outcomes. Many in the field contend that the time has come for instructional communication researchers to define instructional communication theories, test hypotheses, tie research efforts to learning outcomes, and clarify key terms. The present study addressed these shortcomings by proposing the Content Relevance Centric Theory and testing related hypotheses.

The research occurred in a professional training environment and involved the use of a modified content relevance instrument …

Angiotensin Ii Induction Of Regional Effects In Murine Vasculature, Albert Phillip Owens Iii

University of Kentucky Doctoral Dissertations

The renin angiotensin system (RAS) exerts many diverse physiological functions throughout the body, mediated by its effector peptide, angiotensin II (AngII). AngII has been linked with a variety of different functions ranging from the initiation of severe vascular pathologies, such as atherosclerosis and abdominal aortic aneurysm (AAA), to mundane physiological processes of fluid homeostasis, vascular contraction, and regulation of blood pressure. To provide a potential link between these functions, an in-depth analysis of regional effects of AngII on aortic vasculature was performed.

The studies presented in this dissertation tested the overall hypothesis of whether regional changes exist in the vasculature …

Parental Choice Of Nondenominational Christian Education: Reasons For Choice, Exit, And The Types And Sources Of Information Used, Robert M. Hall

University of Kentucky Doctoral Dissertations

School Choice is a topic that finds itself at the top of school reform and political agendas across the United States, while also being a significant focal point in the educational literature. However, little attention in the debate has been placed on private, independent school choice – including private religious school choice – despite that data that shows “seventy-nine percent of all private schools had a religious affiliation in 1999– 2000: 30 percent . . . affiliated with the Roman Catholic Church, and 49 percent with other religious groups” (U.S. Department of Education, 2002, p. 3) and that “initial research …

Utilizing Mixed Surfactants For Simultaneous Pore Templating And Active Site Formation In Metal Oxides, Mohammed Shahidur Rahman

University of Kentucky Doctoral Dissertations

Self-assembled nonionic alkyl glycoside surfactants are of interest for creating functional adsorption and catalytic sites at the surface of mesoporous metal oxides, but they typically impart poor long-range order when used as pore templates. Improved order and control over the functional site density may be achieved by mixing them with a cationic surfactant. To confirm this hypothesis, we investigate the lyotropic liquid crystalline (LLC) phase behavior of aqueous solutions of the functional nonionic surfactant n-dodecyl β-D-maltoside (C₁₂G₂) and cationic cetyltrimethylammonium bromide (C₁₆TAB). A ternary phase diagram of the C₁₆TAB-C₁₂G_{2 …}

Insights Into Expression, Cellular Localization, And Regulation Of Supernatant Protein Factor, A Putative Regulator Of Cholesterol Biosynthesis, Elzbieta Ilona Stolarczyk

University of Kentucky Doctoral Dissertations

SPF (Supernatant Protein Factor) is a cytosolic protein that stimulates at least two enzymes in the cholesterol biosynthetic pathway: squalene monooxygenase and HMGCoA reductase. The mechanism of action has not been established but may be related to lipid transfer between intracellular membranes.

There are three human genes for SPF: SEC14L2 (SPF1), SEC14L3 (SPF2) and SEC14L4 (SPF3). The present study differentiates these closely related genes by evaluating their tissue-specific and relative expression levels. SPF1 mRNA was found to be most abundant in liver, mammary gland and stomach. SPF2 showed negligible expression in all tissues tested; SPF3 expression pattern was similar to …

Vortex Model Of Open Channel Flows With Gravel Beds, Brian James Belcher

University of Kentucky Doctoral Dissertations

Turbulent structures are known to be important physical processes in gravel-bed rivers. A number of limitations exist that prohibit the advancement and prediction of turbulence structures for optimization of civil infrastructure, biological habitats and sediment transport in gravel-bed rivers. This includes measurement limitations that prohibit characterization of size and strength of turbulent structures in the riverine environment for different case studies as well as traditional numerical modeling limitations that prohibit modeling and prediction of turbulent structure for heterogeneous beds under high Reynolds number flows using the Navier-Stokes equations. While these limitations exist, researchers have developed various theories for the structure …

Music And Identity In Circuit Chautauqua: 1904-1932, Paige Clark Lush

University of Kentucky Doctoral Dissertations

This dissertation addresses the place of music in circuit chautauqua, the place of circuit chautauqua in American culture, and the role of music in defining that place. It takes into account the perception of chautauqua as a conduit by which higher culture and urban intellectual discourse could reach rural Americans, and the implications of this perception on musical programming.

The heyday of the circuit chautauqua movement (1904-1932) occurred during a time of considerable interaction between, and discussion of, entertainment and education in the United States. Music was important to the self-image of those involved in the entertainment and education industries, …

Investigations Of S-Glutathionylation Of Brain Proteins In The Progression Of Alzheimer's Disease And Of A Potential Glutatione Mimetic As A Treatment Of Alzheimer's Disease, Shelley Faye Newman

University of Kentucky Doctoral Dissertations

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by neurofibrillary tangles, senile plaques and loss of synapses. Many studies support the notion that oxidative stress plays an important role in AD pathogenesis. Previous studies from our laboratory employed redox proteomics to identify oxidatively modified proteins in the AD inferior parietal lobule (IPL). The proteins were consistent with AD pathology and have been central to further investigations of the disease. The present study was focused on the identification of specific targets of protein S-glutathionylation in AD, early AD (EAD), and mild cognative impairment (MCI) using a redox proteomics approach. In AD …

Assessing Factors Influencing Participation And Dissemination In Community-Based Public Health Coalitions: An Exploration Of Social Change, Chad Tyler Morris

University of Kentucky Doctoral Dissertations

The community-based public health coalition has proliferated in public health practice since the 1970‘s as a favored means of achieving community participation in public health promotion. There is concern, however, that many contemporary coalitions are not particularly inclusive, and that population health indicators fail to demonstrate significant improvement in health outcomes resultant from coalition practice. This dissertation research was designed to critically examine participation and dissemination of coalition-derived ideas through ethnographic study of five community-based participatory public health coalitions in the United States. The research answers calls from public health scholars to improve upon the coalition theory base and to …

Painting The Mountains: An Investigation Of Tourist Art In North America, Kristin Mary Agnes Helen Kant

University of Kentucky Doctoral Dissertations

This study examines the use of regional cultural icons, like hillbillies, nineteenth century pioneer caricatures, and rural/wilderness landscapes, in paintings from an Appalachian tourist center. These icons, produced by the public media’s portrayal of the Appalachian region over several generations, contribute to a sense of cultural difference associated with people of Appalachia. The research question driving this project is: would cultural distinctiveness exist if cultural stereotypes were not a part of the tourist center’s local economics, politics, and social life? Building on ideas from consumption studies, this project explores consumption practices of artists and tourists as they interact with icons …

Exploring Lesbian And Gay Experiences With Individuals, Systems, And Environments: Patterns Of Response To Heterosexist Prejudice And Discrimination, James Russell Couch

University of Kentucky Doctoral Dissertations

While the general social climate in the U.S. has become more accepting and tolerant of sexual minority individuals, heterosexist discrimination, prejudice and violence continues to affect LGBT individuals, families and communities. While much research literature exists on the experience of minority stress and the psychological consequences of minority stress on sexual minorities, little research has been produced that examines sexual minority coping. Within the last decade, heteronegativity has been suggested as a possible coping response to heterosexism. The goal of the present study was to understand sexual minority responses to heterosexism (including heteronegativity) in a variety of contexts and circumstances. …

Experimental And Molecular Dynamics Simulation Studies Of Partitioning And Transport Across Lipid Bilayer Membranes, Ravindra Wadhumal Tejwani

University of Kentucky Doctoral Dissertations

Most drugs undergo passive transport during absorption and distribution in the body. It is desirable to predict passive permeation of future drug candidates in order to increase the productivity of the drug discovery process. Unlike drug-receptor interactions, there is no receptor map for passive permeability because the process of transport across the lipid bilayer involves multiple mechanisms. This work intends to increase the understanding of permeation of drug-like molecules through lipid bilayers.

Drug molecules in solution typically form various species due to ionization, complexation, etc. Therefore, species specific properties must be obtained to bridge the experiment and simulations. Due to …

Identification And Characterization Of Host Factors Involved In Tombusvirus Replication, Yi Jiang

University of Kentucky Doctoral Dissertations

Positive strand RNA viruses are intracellular parasites, and their genome replication and infection involves complex virus-host interactions. Therefore, identification of host factors and dissection of their functions during virus replication could facilitate our understanding of the mechanism of virus infection. Those host factors may also provide new targets for viral disease control. Tomato bushy stunt virus (TBSV) has recently become one of the model viruses to study positive strand RNA virus replication and hostvirus interactions. To identify host factors involved in TBSV replication we used yeast as a model host. Co-expression of the replication proteins and a replicon RNA (DI …

Investigation Of Surface Fine Grained Laminae, Streambed, And Streambank Processes Using A Watershed Scale Hydrologic And Sediment Transport Model, Joseph Paul Russo

University of Kentucky Doctoral Dissertations

Sediment transport at the watershed scale in the Bluegrass Region of Kentucky is dominated by surface fine grained laminae, streambed, and streambank erosion; high instream sediment storage; and surface erosion processes. All these processes can be impacted by agricultural, urban, and suburban land-uses as well as hydrologic forcing. Understanding sediment transport processes at the watershed scale is a need for budgeting and controlling sediment pollution, and watershed modeling enables investigation of the cumulative effect of sediment processes and the parameters controlling these processes upon the entire sediment budget for a watershed. Sediment transport is being modeled by coupling the hydrologic …