Digital Commons Network^™

Staying Out: Reentry Protective Factors Among Rural Women Offenders, Michele Staton, Megan F. Dickson, Martha Tillson, J. Matthew Webster, Carl G. Leukefeld

Behavioral Science Faculty Publications

The current study examines protective factors for women who transition from county jails to rural Appalachian communities, areas with limited health and behavioral health services. The study included drug-using women recruited from three jails in rural Appalachia and followed-up at 12-months post-release. Analyses focused on differences between women who remained in the community and those who returned to custody, as well as a multivariate model to determine protective factors for reentry success. At the bivariate level, staying out of jail was associated with being older, having a job, not using drugs, stable housing, receiving health treatment, and having prosocial peers. …

Modeling And Simulation Of A Utility-Scale Battery Energy Storage System, Oluwaseun M. Akeyo, Vandana Rallabandi, Nicholas Jewell, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

This paper presents the modeling and simulation study of a utility-scale MW level Li-ion based battery energy storage system (BESS). A runtime equivalent circuit model, including the terminal voltage variation as a function of the state of charge and current, connected to a bidirectional power conversion system (PCS), was developed based on measurements from an operational utility-scale battery demonstrator. The accelerated response of the battery unit was verified by pulse discharging it from maximum to minimum SOC and its application for grid resiliency was demonstrated through an example droop control frequency response. For the purpose of validating the equivalent BESS …

Load Variation Reduction By Aggregation In A Community Of Rooftop Pv Residences, Huangjie Gong, Vandana Rallabandi, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

This paper performs computational studies and develops control schemes for a virtual power plant (VPP) network formed by a community of homes with rooftop solar PV generation, and battery energy storage. Appropriate control and scheduling of the battery operations, and peer-peer power flow between the homes provide a possible solutions for reducing the higher costs and uncertainties brought to grid by high solar PV penetration. The residential community studied here includes twelve homes categorized into four types depending on whether they have energy storage or rooftop solar PV panels. The homes exchange power among themselves, and the real-time electricity rate …

Targeting Pathogenic Lafora Bodies In Lafora Disease Using An Antibody-Enzyme Fusion, M. Kathryn Brewer, Annette M. Uittenbogaard, Grant L. Austin, Dyann M. Segvich, Anna Depaoli-Roach, Peter J. Roach, John J. Mccarthy, Zoe R. Simmons, Jason A. Brandon, Zhengqiu Zhou, Jill Zeller, Lyndsay E. A. Young, Ramon C. Sun, James R. Pauly, Nadine M. Aziz, Bradley L. Hodges, Tracy R. Mcknight, Dustin D. Armstrong, Matthew S. Gentry

Molecular and Cellular Biochemistry Faculty Publications

Lafora disease (LD) is a fatal childhood epilepsy caused by recessive mutations in either the EPM2A or EPM2B gene. A hallmark of LD is the intracellular accumulation of insoluble polysaccharide deposits known as Lafora bodies (LBs) in the brain and other tissues. In LD mouse models, genetic reduction of glycogen synthesis eliminates LB formation and rescues the neurological phenotype. Therefore, LBs have become a therapeutic target for ameliorating LD. Herein, we demonstrate that human pancreatic α-amylase degrades LBs. We fused this amylase to a cell-penetrating antibody fragment, and this antibody-enzyme fusion (VAL-0417) degrades LBs in vitro and dramatically reduces LB …

Ccr3 Inhibition For Ocular Angiogenesis And Macular Degeneration, Jayakrishna Ambati

Ophthalmology and Visual Science Faculty Patents

Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of inhibitors of the CCR3 receptor or its ligands eotaxin (CCL11), eotaxin-2 (CCL24) or eotaxin-3 (CCL26) inhibits ocular angiogenesis.

The Social Documentary Photography Of Milton Rogovin, Christopher Fulton

Civil Rights

Milton Rogovin (1909–2011) dedicated his photographic career to capturing the humanity of working-class people around the world—coal miners, factory workers, the urban poor, the residents of Appalachia, and other marginalized groups. He worked to equalize the relationship between photographer and subject in the making of pictures and encouraged his subjects' agency by photographing them on their own terms. Rogovin's powerful insight and immense sympathy for his subjects distinguish him as one of the most original and important documentary photographers in American history.

Edited by Christopher Fulton, The Social Documentary Photography of Milton Rogovin is a multi-disciplinary study of the photographer's …

Social Media Use Among Nonprofit Organizations In Rural Appalachia, Mckenzie Liegel, Jodi L. Southerland, Katie Baker

Journal of Appalachian Health

Introduction: Social media have changed the landscape of health communication for nonprofit organizations (NPOs). Yet, adoption and use of social media lag among NPOs in rural Appalachia due largely to limited infrastructure development.

Methods: Semi-structured phone interviews were conducted in January–March 2018 with 21 NPO representatives in an 8-county region of rural Appalachian Tennessee. NPO representatives were asked questions pertaining to social media use and message content, effective communication strategies, and best practices in social media use. Transcripts were analyzed in April–May 2018 using thematic analysis.

Results: The majority of NPOs had a Facebook page and recognized its …

West Virginia’S Sugary Drink Tax: Examining Print Media Frames In Local News Sources, Lauri Andress, Ogaga Urhie, Christine Compton

Journal of Appalachian Health

Introduction: Framing is an important aspect of the policy process that helps the public and decision makers sort through and resolve highly charged claims about an issue. Through slight changes in the presentation of issues, a framing effect may alter public support. The way a proposed sugary drink tax is discussed in public discourse and by the media significantly influences policy acceptance. Given the public health significance of obesity and diabetes in West Virginia (WV) the study of media frames employed to represent a sugary drink tax policy is useful.

Methods: Using quantitative content analysis, this study assessed news articles—published …

Best Websites For Careers And Job Hunting, Jennifer A. Bartlett

Library Faculty and Staff Publications

Here are just a few tried-and-true free websites to help our patrons (and maybe us!) get started on the road to that perfect job.

Key Mechanisms By Which Post-Icu Activities Can Improve In-Icu Care: Results Of The International Thrive Collaboratives, Kimberley J. Haines, Carla M. Sevin, Elizabeth Hibbert, Leanne M. Boehm, Krishna Aparanji, Rita N. Bakhru, Anthony J. Bastin, Sarah J. Beesley, Brad W. Butcher, Kelly Drumright, Tammy L. Eaton, Thomas Farley, Penelope Firshman, Andrew Fritschle, Clare Holdsworth, Aluko A. Hope, Annie Johnson, Michael T. Kenes, Babar A. Khan, Janet A. Kloos, Erin K. Kross, Belinda J. Macleod-Smith, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Howard L. Saft, Andrew Slack, Joanna Stollings, Gerald Weinhouse

Internal Medicine Faculty Publications

Objective: To identify the key mechanisms that clinicians perceive improve care in the intensive care unit (ICU), as a result of their involvement in post-ICU programs.

Methods: Qualitative inquiry via focus groups and interviews with members of the Society of Critical Care Medicine’s THRIVE collaborative sites (follow-up clinics and peer support). Framework analysis was used to synthesize and interpret the data.

Results: Five key mechanisms were identified as drivers of improvement back into the ICU: (1) identifying otherwise unseen targets for ICU quality improvement or education programs—new ideas for quality improvement were generated and greater attention paid to detail in …

“Come Hell And High Water”: The Role Of Archivists, Historical Myths, And Activism In Communities Facing Repeated Extreme Flooding Events, Jay-Marie Bravent, Kari A. Greenwalt, Shawn Gladden

Library Presentations

While the names Harvey, Sandy, and Katrina ring loudly in the ears of many today – can we still learn valuable lessons in the archives from Diane, Camille, and Agnes? Climate change increasingly contributes to not only more frequent and more violent tropical cyclogenesis, but repeated extreme flooding events caused by unnamed weather systems, supercells, dam failures, and surges from rising oceans. These events have opened questions of survival for communities across the United States, and recent examples show that some communities indeed face pressure to abandon their long-standing ground and forego rebuilding.

In a 2013 article titled “Come Hell …

¿Poder Del Discurso O Discurso De Poder? La Representación De Los Migrantes Ecuatorianos En La Utopía De Madrid, Francesco Masala

Nomenclatura: aproximaciones a los estudios hispánicos

After enduring a decade of economic, climatic, and political problems, between 1999 and 2006, more than 900,000 Ecuadorians left their country (INEC 2007). This process marked the beginning of a major migratory movement which has caused Spain to become a premier destination. The response to such migration has been disparate, yet both Ecuadorian and Spanish artists (as well as the Spanish press) have shown the different perspectives related to a discriminatory ideology. This article focuses on the representation of Ecuadorians in Spain in the 21st century. Despite the large production of novels related to this topic, the one that best …

Ubiquitin-Mediated Proteasome Degradation Regulates Optic Fissure Fusion, Warlen Pereira Piedade, Sydney Veith, Jakub Konrad Famulski

Biology Faculty Publications

Optic fissure fusion is a critical event during retinal development. Failure of fusion leads to coloboma, a potentially blinding congenital disorder. Pax2a is an essential regulator of optic fissure fusion and the target of numerous morphogenetic pathways. In our current study, we examined the negative regulator of pax2a expression, Nz2, and the mechanism modulating Nlz2 activity during optic fissure fusion. Upregulation of Nlz2 in zebrafish embryos resulted in downregulation of pax2a expression and fissure fusion failure. Conversely, upregulation of pax2a expression also led to fissure fusion failure suggesting Pax2 levels require modulation to ensure proper fusion. Interestingly, we discovered Nlz2 …

The Antibacterial Effect Of Sonication And Its Potential Medical Application, Srinath Kamineni, Chifu B. Huang

Orthopaedic Surgery and Sports Medicine Faculty Publications

Introduction: Recent applications of ultrasonic probes include cataract removal and tennis elbow treatment. Early data support the use of ultrasonic probe debridement in the treatment of recalcitrant diabetic foot ulcers. No data are available concerning the potential antibacterial properties of the clinical grade, lower energy ultrasound probes. We investigated the effect of a clinically available ultrasonic debridement probe with respect to bacterial viability.

Methods: A commercially available Tenex sonication machine with a Tx1 probe was used for this study. Three bacterial strains, aerobic and anaerobic, were investigated, G-negative (Porphyromonas gingivalis) and G-positive bacteria (Staphylococcus aureus …

Future And Value: The Library As Strategic Partner [Ebug 2019], Antje Mays

Library Presentations

This keynote presentation was based on the 2018 Charleston Library Conference. The session outlined broader economic shifts facing higher education and libraries, then facilitated audience participation vis anonymous live poll at the Ex Libris Bluegrass Users Group (eBUG) annual conference focused on library systems.

Broader economic trends spawn budget pressures for education and libraries, prompting a plethora of studies on the value and relevance of libraries. Numerous reports on economic decline in libraries and studies with mixed pronouncements on the value of libraries have led to a negative self-image within the library profession. Yet libraries' leadership in connecting learners to …

Packed Red Blood Cell Transfusion Associates With Acute Kidney Injury After Transcatheter Aortic Valve Replacement, Akeel M. Merchant, Javier A. Neyra, Abu Minhajuddin, Lauren E. Wehrmann, Richard A. Mills, Sarah K. Gualano, Dharam J. Kumbhani, Lynn C. Huffman, Michael E. Jessen, Amanda A. Fox

Internal Medicine Faculty Publications

Background: Acute kidney injury after cardiac surgery significantly associates with morbidity and mortality. Despite not requiring cardiopulmonary bypass, transcatheter aortic valve replacement patients have an incidence of post-procedural acute kidney injury similar to patients who undergo open surgical aortic valve replacement. Packed red blood cell transfusion has been associated with morbidity and mortality after cardiac surgery. We hypothesized that packed red blood cell transfusion independently associates with acute kidney injury after transcatheter aortic valve replacement, after accounting for other risk factors.

Methods: This is a single-center retrospective cohort study of 116 patients undergoing transcatheter aortic valve replacement. Post-transcatheter aortic valve …

Composite Membranes Derived From Cellulose And Lignin Sulfonate For Selective Separations And Antifouling Aspects, Andrew Steven Colburn, Ronald J. Vogler, Aum Patel, Mariah Bezold, John D. Craven, Chunqing Liu, Dibakar Bhattacharyya

Chemical and Materials Engineering Faculty Publications

Cellulose-based membrane materials allow for separations in both aqueous solutions and organic solvents. The addition of nanocomposites into cellulose structure is facilitated through steric interaction and strong hydrogen bonding with the hydroxy groups present within cellulose. An ionic liquid, 1-ethyl-3-methylimidazolium acetate, was used as a solvent for microcrystalline cellulose to incorporate graphene oxide quantum dots into cellulose membranes. In this work, other composite materials such as, iron oxide nanoparticles, polyacrylic acid, and lignin sulfonate have all been uniformly incorporated into cellulose membranes utilizing ionic liquid cosolvents. Integration of iron into cellulose membranes resulted in high selectivity (> 99%) of neutral …

Surveilling Strangers: The Disciplinary Biopower Of Digital Genre Assemblages, Lauren E. Cagle

Writing, Rhetoric, and Digital Studies Faculty Publications

This article identifies and names the digital visual genre of strangershots: photographs of strangers taken without their knowledge or consent and then shared online, accruing derogatory comments as they circulate through online networks. By closely describing a specific strangershot posted on Reddit and then connecting it to further examples, I aim to demonstrate that strangershots constitute a genre identifiable by the recurring social actions they accomplish by producing similar responses to recurring social situations. After identifying the genre, I apply actor-network theory to demonstrate how this genre is produced by assemblages of humans and non-human technologies. Following that, I …

Waved: A Coreless Axial Flux Pm Motor For Drive Systems With Constant Power Operation, Narges Taran, Vandana Rallabandi, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

In this paper, a two-phase coreless AFPM machine with wave winding, 2-stators, and 3-rotors for traction applications is studied. A highly general optimization method, employing 3D FEA as the computational engine is employed. Number of poles in addition to other geometrical variables are included as independent optimization variables. A method for extending the speed range by rotating one of the stator discs with respect to the other at constant power operation is proposed. An inverter configuration including Si and wide band gap devices is proposed to be employed in conjunction with the machine under study. The study includes a comparison …

Modeling And Control Of A Multiport Converter Based Ev Charging Station With Pv And Battery, Yibin Zhang, Jiangbiao He, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

As an environmental friendly vehicle, the increasing number of electrical vehicles (EVs) leads to a pressing need of widely distributed charging stations, especially due to the limited on-board battery capacity. However, fast charging stations, especially super-fast charging stations may stress power grid with potential overload at peaking time, sudden power gap and voltage sag. This paper discusses the detailed modeling of a multiport converter based EV charging station integrated with PV power generation, and battery energy storage system, by using ANSYS TwinBuilder. In this paper, the control scheme and combination of PV power generation, EV charging station, and battery energy …

Electric Aircraft System Co-Simulation Including Body, Propeller, Propulsion, And Energy Storage Models, Damien Lawhorn, Vandana Rallabandi, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

This paper discusses the multi physics modeling of an electric aircraft with distributed electric propulsion. Mathematical models for the aircraft body, propellers, propulsive motors, power electronics inverters, and batteries are developed. Two types of models are proposed for the power electronics inverters and electric machines, namely, average models which allow study of the aircraft performance under a specified mission profile, and detailed switching models used for transient examination. A new simulation framework was developed to allow communication between these two types of models so that losses and thermal stresses in the power electronics converters can be estimated especially during takeoff, …

Reducing Construction Costs Through Effective Field Communication And Administration, Gabriel B. Dadi, Roy E. Sturgill Jr., Steven Waddle, Steven Douglas Kreis

Kentucky Transportation Center Research Report

Falling Road Fund receipts have placed added strain on the Kentucky Transportation Cabinet’s (KYTC) already-underfunded highway program. Revenue declines have increased the urgency of improving the efficiency and cost-effectiveness of the Cabinet’s operations. One method KYTC can use to realize greater cost savings is improving the administration of construction projects. Effective field communication and administration helps control construction costs, enhances quality, and minimizes delays and claims. One challenge the Cabinet will need to confront to more effectively administer projects, however, is the loss of institutional knowledge associated with staff attrition. The report documents KYTC current methods for project staffing, communication, …

Impact Of Tobacco-Pack Pictorial Warnings On Youth And Young Adults: A Systematic Review Of Experimental Studies, Diane B. Francis, Nia Mason, Jennifer Cornacchione Ross, Seth M. Noar

Communication Faculty Publications

Introduction:
We conducted a systematic review of the experimental literature on the impact of tobacco-pack pictorial warning labels (PWLs) on youth and young adults.

Methods:
We systematically searched computerized databases and the reference list of relevant articles. We included studies that used an experimental protocol to assess PWLs. Studies had to report findings for youth or young adult samples (aged < 30 years). Thirty-one studies met the inclusion criteria, with a total sample size of 27506. Two coders independently coded all study characteristics and outcomes.

Results:
Twenty-eight studies experimentally evaluated PWLs for cigarette packs while three studies evaluated PWLs for smokeless tobacco packs. Generally, PWLs led to higher attention, stronger cognitive and affective reactions, more negative pack attitudes and smoking attitudes, and increased intentions not …

Challenges Met In Using Bottom Ash As A Landfill Drainage Media, William M. Strachan

World of Coal Ash Proceedings

No abstract provided.

Alcohol Sale Status And Homicide Victimization In Kentucky, 2005-2012: Is There A Spatial Association?, Hanan Abdulghafoor Khaleel, Sabrina Brown, Steven T. Fleming, W. Jay Christian

Epidemiology and Environmental Health Faculty Publications

To date, the association between the alcohol sale status of decedents’ residence and alcohol-related homicide victimization have not been studied as far as we know. The current study aims to: i) determine whether homicide victims who were residents of wet counties had higher odds of testing positive for alcohol than their counterparts in moist or dry counties after adjusting for confounders; ii) determine whether homicides and alcohol-related homicides tend to cluster spatially; iii) determine whether the aforementioned associations exist only in highly-populated counties. A multilevel logistic regression analysis was used to analyze the data on homicide victims in the Kentucky …

Secreted Tumor-Associated Cytochrome As A Blood-Based Biomarker For Cancer, Rolf Joseph Craven

Pharmacology and Nutritional Sciences Faculty Patents

Disclosed herein are methods for detecting Pgrmc 1 in bodily fluids, e.g., blood, plasma and serum, wherein detection of Pgrmcl is a biomarker for the presence of cancer, e.g., lung cancer or head or neck cancer. Pgrmc 1 levels in bodily fluids may be used to predict patient prognosis, e.g., survival and response to therapy.

Automating The Authority Control Process, Stacey Wolf

OVGTSL 2019

Authority control is an important part of cataloging since it helps provide consistent access to names, titles, subjects, and genre/forms. There are a variety of methods for providing authority control, ranging from manual, time-consuming processes to automated processes. However, the automated processes often seem out of reach for small libraries when it comes to using a pricey vendor or needing a cataloger with particular expertise. This presentation will introduce several ideas on how to handle authority control using a variety of tools, both paid and free. The presenter will describe how their library handles authority control; compare vendors and programs …

Opening Keynote: Storytelling & Power In Technical Services, Hannah Buckland

OVGTSL 2019

Stories—as well as language and words themselves—articulate value, identifying what is significant about our histories and our relationships. In this way, storytelling is a form of power, a way of organizing the world. Technical services work, in turn, does more than create, locate, or describe; it also contributes to an ongoing story libraries communicate to users, a story about how something came to be, a story about power dynamics, and a story of how something is connected to everything.

Inducing Incentive Sensitization Of Exercise Reinforcement Among Adults Who Do Not Regularly Exercise—A Randomized Controlled Trial, Kyle D. Flack, Kelsey Elise Ufholz, Luann Johnson, James N. Roemmich

Dietetics and Human Nutrition Faculty Publications

Background

Increasing exercise reinforcement, or decreasing sedentary reinforcement, may reduce sedentary activity and promote habitual exercise. Repeated exposures to a reinforcer may increase its reinforcing value (i.e., incentive sensitization). It is not yet known whether incentive sensitization occurs for exercise or factors associated with incentive sensitization for exercise reinforcement. The purpose was to determine whether exercise exposures increase exercise reinforcement relative to a sedentary alternative and whether this sensitization of exercise reinforcement would alter physical or sedentary behavior. This work also determined whether exercise dose, intensity, and preference and tolerance for exercise intensity were associated with incentive sensitization of exercise. …

One Amino Acid Change Of Angiotensin Ii Diminishes Its Effects On Abdominal Aortic Aneurysm, Ya Wang, Yinchuan Xu, Congqing Wu, Hongguang Xia, Yingchao Wang, Jinliang Nan, Jinghai Chen, Hong Yu, Wei Zhu, Peng Shi, Alan Daugherty, Hong S. Lu, Jian'an Wang

Saha Cardiovascular Research Center Faculty Publications

Angiotensin (Ang) A is formed by the decarboxylation of the N terminal residue of AngII. The present study determined whether this one amino acid change impacted effects of AngII on abdominal aortic aneurysm (AAA) formation in mice. Computational analyses implicated that AngA had comparable binding affinity to both AngII type 1 and 2 receptors as AngII. To compare effects of these two octapeptides in vivo, male low-density lipoprotein receptor (Ldlr) or apolipoprotein E (Apoe) deficient mice were infused with either AngII or AngA (1 μg/kg/min) for 4 weeks. While AngII infusion induced AAA consistently in …