Digital Commons Network^™

Integrated Ac To Ac Converters For Single-Phase Input To Two-Phase Output Motor Drives, Yibin Zhang, Damien L. Lawhorn, Peng Han, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

The single-phase to two-phase converters have become attractive for low-power motor drives due to the full electromagnetic isolation between phases of two-phase motors. One of the commonly used topologies is the ac/dc/ac pulse width modulation (PWM) converter which contains twelve active power semiconductor switches and a common dc link. To minimize the system cost and size for low power applications, an integrated ac/ac converter with a single-phase input and a two-phase output which reduces the switch count to six is proposed in this paper. Additionally, modulation scheme and filters for the proposed converter are developed and modeled in details. In …

Integrated Modular Motor Drives Based On Multiphase Axial-Flux Pm Machines With Fractional-Slot Concentrated Windings, Peng Han, Greg Heins, Yibin Zhang, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

The integrated motor drive (IMD) concept with possible modularization has attracted much attention in a broad spectrum of applications ranging from low-power general-purpose industrial drives to high-power electric propulsion. This paper presents the feasibility study and performance evaluation of using common axial-flux permanent-magnet (AFPM) machines with fractional-slot concentrated windings in IMDs, with the same diameter and a minimum increase in its axial length. Different winding configurations are compared in terms of the torque/power capability and fault tolerance without changing the winding current rating. The possibility of further torque improvement is discussed from the perspective of making full use of the …

Analysis Of Torque Production In Axial-Flux Vernier Pm Machines Of The Magnus Type, Murat G. Kesgin, Peng Han, Damien Lawhorn, Dan M. Ionel

Power and Energy Institute of Kentucky Faculty Publications

The paper presents a study of the torque production in a novel vernier-type axial-flux permanent magnet (PM) machine topology named MAGNUS. Two computational methods are employed, one based on the 3D FEA Maxwell stress calculations on individual stator and rotor components and one based on the analytical derivation of the air-gap flux density harmonics. Examples are provided for a design with a 40-pole spoke-type PM rotor and two stators, one active including a 3-phase winding with 6 concentrated coils wound around main teeth in a single layer arrangement and a second stator that has neither coils nor main slots and …

Optimizing Critical Illness Recovery: Perspectives And Solutions From The Caregivers Of Icu Survivors, Carla M. Sevin, Leanne M. Boehm, Elizabeth Hibbert, Anthony J. Bastin, James C. Jackson, Joel Meyer, Tara Quasim, Rita N. Bakhru, Ashley A. Montgomery-Yates, Andrew Slack, Mary Still, Giora Netzer, Mark E. Mikkelsen, Theodore J. Iwashyna, Kimberly J. Haines, Joanne Mcpeake

Internal Medicine Faculty Publications

Objectives:
To understand the unmet needs of caregivers of ICU survivors, how they accessed support post ICU, and the key components of beneficial ICU recovery support systems as identified from a caregiver perspective.

Design:
International, qualitative study.

Subjects:
We conducted 20 semistructured interviews with a diverse group of caregivers in the United States, the United Kingdom, and Australia, 11 of whom had interacted with an ICU recovery program.

Setting:
Seven hospitals in the United States, United Kingdom, and Australia.

Interventions:
None.

Measurements and Main Results:
Content analysis was used to explore prevalent themes related to unmet needs, as well as …

Callus Induction And Plant Regeneration Of Poa Pratensis 'Nasu' Seeds Carried By China Recoverable Satellite Shijian‐8, Yinghua Guo, Lei Han, Guansheng Ju, Zhenyuan Sun

IGC Proceedings (1977-2023)

No abstract provided.

Application Of Eh-Ph Diagrams On Acid Leaching Systems For The Recovery Of Rees From Bastnaesite, Monazite And Xenotime, Peijia Lin, Xinbo Yang, Joshua M. Werner, Rick Q. Honaker

Mining Engineering Faculty Publications

Bastnaesite, monazite and xenotime are rare earth minerals (REMs) that are typical sources for rare earth elements (REEs). To advance the understanding of their leaching and precipitation behavior in different hydrometallurgical processes, Eh-pH diagrams were constructed and modified using the HSC 9.9 software. The aqueous stability of rare earth elements in H₂O and acid leaching systems, i.e., the REE-Ligands-H₂O systems, were depicted and studied based on the Eh-pH diagrams. This study considers the most relevant lixiviants, their resulting equilibrium states and the importance in the hydrometallurgical recovery of rare earth elements (REMs). A literature review was …

The Tacit Knowledge Dilemma In Open Science, C. Sean Burns

Information Science Presentations

A talk about the role that knowledge management (and sub areas) might play in open science. The open science movement has the goal of making transparent as much of the scientific process as is possible. This entails making publicly available (open source, access, etc.) the parts of the scientific workflow, such as the data, the software code, the manuscripts, that are used or generated in the process of doing research. However, Michael Polanyi's theory of tacit knowledge raises a dilemma that knowledge management researchers might be able to address. Specifically, if we accept the theory of tacit knowledge, the idea …

Feeding Cannabidiol (Cbd)-Containing Treats Did Not Affect Canine Daily Voluntary Activity, Elizabeth M. Morris, Susanna E. Kitts-Morgan, Dawn M. Spangler, Jessica Gebert, Eric S. Vanzant, Kyle R. Mcleod, David L. Harmon

Animal and Food Sciences Faculty Publications

Growing public interest in the use of cannabidiol (CBD) for companion animals has amplified the need to elucidate potential impacts. The purpose of this investigation was to determine the influence of CBD on the daily activity of adult dogs. Twenty-four dogs (18.0 ± 3.4 kg, 9 months−4 years old) of various mixed breeds were utilized in a randomized complete block design with treatments targeted at 0 and 2.5 mg (LOW) and at 5.0 mg (HIGH) CBD/kg body weight (BW) per day split between two treats administered after twice-daily exercise (0700–0900 and 1,700–1,900 h). Four hours each day [1,000–1,200 h (a.m.) …

Cross-Sectional Exploration Of Plasma Biomarkers Of Alzheimer's Disease In Down Syndrome: Early Data From The Longitudinal Investigation For Enhancing Down Syndrome Research (Life-Dsr) Study, James A. Hendrix, David C. Airey, Angela Britton, Anna D. Burke, George T. Capone, Ronelyn Chavez, Jacqueline Chen, Brian Chicoine, Alberto C. S. Costa, Jeffrey L. Dage, Eric Doran, Anna Esbensen, Casey L. Evans, Kelley M. Faber, Tatiana M. Foroud, Sarah Hart, Kelsey Haugen, Elizabeth Head, Suzanne Hendrix, Hampus Hillerstrom, Frederick A. Schmitt

Sanders-Brown Center on Aging Faculty Publications

With improved healthcare, the Down syndrome (DS) population is both growing and aging rapidly. However, with longevity comes a very high risk of Alzheimer’s disease (AD). The LIFE-DSR study (NCT04149197) is a longitudinal natural history study recruiting 270 adults with DS over the age of 25. The study is designed to characterize trajectories of change in DS-associated AD (DS-AD). The current study reports its cross-sectional analysis of the first 90 subjects enrolled. Plasma biomarkers phosphorylated tau protein (p-tau), neurofilament light chain (NfL), amyloid β peptides (Aβ_1-40, Aβ_1-42), and glial fibrillary acidic protein (GFAP) were undertaken with …

Sustainable America In The Twenty-First Century: A Critique Of President Clinton's Council On Sustainable Development, Kristina M. Tridico

Journal of Natural Resources & Environmental Law

No abstract provided.

Container Deposit: What Is It, And Is It Right For Kentucky?, Gregory D. Stumbo

Journal of Natural Resources & Environmental Law

No abstract provided.

Progress In Silage Research In Relation To Animal Production And Food Safety, N. Nishino

IGC Proceedings (1977-2023)

No abstract provided.

The Public’S Perceptions Of Government Officials’ Communication In The Wake Of The Covid-19 Pandemic, Shaniece B. Bickham, Diane B. Francis

Communication Faculty Publications

Early news coverage in the US about the COVID-19 pandemic focused on information released from local, state and federal government officials. With an emphasis on US government at these levels, this study examined whether the public’s credibility perceptions and trust in government, along with message exposure, influenced their adherence to information from the government about (a) stay-at-home orders, (b) social distancing and (c) COVID-19 testing. Source credibility theory and situational crisis communication theory provided the theoretical framework for this study. Through the survey data analysis, we investigated communication preferences in the wake of the pandemic and whether credibility perceptions differed …

Intrauterine Blood Plasma Platelet-Therapy Mitigates Persistent Breeding-Induced Endometritis, Reduces Uterine Infections, And Improves Embryo Recovery In Mares, Lorenzo G. T. M. Segabinazzi, Igor F. Canisso, Giorgia Podico, Lais L. Cunha, Guilherme Novello, Michael F. Rosser, Shavanh C. Loux, Fabio S. Lima, Marco A. Alvarenga

Maxwell H. Gluck Equine Research Center Faculty Publications

Microorganisms, including pathogenic or opportunistic bacteria and fungi, may gain access to the uterus during breeding, and infectious endometritis plays a major role in equine subfertility. This study aimed to assess the post-breeding inflammatory response, endometrial culture, and embryo recovery of mares susceptible to persistent breeding-induced endometritis (PBIE) treated with plasma-rich (PRP) or -poor (PPP) plasma. Mares (n = 12) susceptible to PBIE had three cycles randomly assigned to receive intrauterine infusions of lactate ringer solution (LRS, control), or autologous PRP or PPP pre- (−48 and −24 h) and post-breeding (6 and 24 h). Mares were bred with fresh …

The Context-Dependent Impact Of Integrin-Associated Cd151 And Other Tetraspanins On Cancer Development And Progression: A Class Of Versatile Mediators Of Cellular Function And Signaling, Tumorigenesis And Metastasis, Sonia F. Erfani, Hui Hua, Yueyin Pan, Binhua P. Zhou, Xiuwei H. Yang

Molecular and Cellular Biochemistry Faculty Publications

As a family of integral membrane proteins, tetraspanins have been functionally linked to a wide spectrum of human cancers, ranging from breast, colon, lung, ovarian, prostate, and skin carcinomas to glioblastoma. CD151 is one such prominent member of the tetraspanin family recently suggested to mediate tumor development, growth, and progression in oncogenic context- and cell lineage-dependent manners. In the current review, we summarize recent advances in mechanistic understanding of the function and signaling of integrin-associated CD151 and other tetraspanins in multiple cancer types. We also highlight emerging genetic and epigenetic evidence on the intrinsic links between tetraspanins, the epithelial-mesenchymal transition …

Naked Dinner: A Comparison Of Dionysian And Apollonian Values Between The Beat Generation And Generation Z, Isha Chauhan

Libraries Award for Undergraduate Scholarship

Beyond popularized sororities and toga days, ‘Greek life’ has taken on a more ideological meaning when considering the impacts of the Dionysian and Apollonian spirits on Generation Z in comparison to past generations, namely the Beat Generation. The rambunctious Beat Generation characterized by efforts in free love and sexuality, opposition to capitalism and exploration of communism, socialization of drugs, and racial disparity defined the American 1950s. Notorious writers Allen Ginsberg and Jack Kerouac were only some of the representative figures of the Beat Generation but hold great significance when compared to Generation Z which has shared the Beat Generation’s fervor …

Artists' Genres: A Brief Introduction To Post-Medieval Western Art, Robert Jensen

Art and Visual Studies Faculty Book Gallery

Artists' Genres is a brief introduction to the history of post-medieval Western art organized by the major genres. The book is designed as a basic textbook for high school- or introductory college-level courses or for individuals simply looking for an interesting guidebook into the art of this period and geographical region.

This is the revised edition of Artists' Genres: A Brief Introduction to Post-Medieval Western Art, which was released in 2018.

Functional Activation Of Newborn Neurons Following Alcohol-Induced Reactive Neurogenesis, Natalie N. Nawarawong, Chelsea G. Nickell, Deann M. Hopkins, James R. Pauly, Kimberly Nixon

Pharmaceutical Sciences Faculty Publications

Abstinence after alcohol dependence leads to structural and functional recovery in many regions of the brain, especially the hippocampus. Significant increases in neural stem cell (NSC) proliferation and subsequent “reactive neurogenesis” coincides with structural recovery in hippocampal dentate gyrus (DG). However, whether these reactively born neurons are integrated appropriately into neural circuits remains unknown. Therefore, adult male rats were exposed to a binge model of alcohol dependence. On day 7 of abstinence, the peak of reactive NSC proliferation, rats were injected with bromodeoxyuridine (BrdU) to label dividing cells. After six weeks, rats underwent Morris Water Maze (MWM) training then were …

Keap1 Is Required For Artesunate Anticancer Activity In Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony Mcdowell Jr., J. Robert Mccorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, Jill M. Kolesar

Pathology and Laboratory Medicine Faculty Publications

Artesunate is the most common treatment for malaria throughout the world. Artesunate has anticancer activity likely through the induction of reactive oxygen species, the same mechanism of action utilized in Plasmodium falciparum infections. Components of the kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway, which regulates cellular response to oxidative stress, are mutated in approximately 30% of non-small-cell lung cancers (NSCLC); therefore, we tested the hypothesis that KEAP1 is required for artesunate sensitivity in NSCLC. Dose response assays identified A549 cells, which have a G333C-inactivating mutation in KEAP1, as resistant to artesunate, with an IC50 of …

Science And Mathematics Teacher Communities Of Practice: Social Influences On Discipline-Based Identity And Self-Efficacy Beliefs, Samuel J. Polizzi, Yicong Zhu, Joshua W. Reid, Brandon Ofem, Sara Salisbury, Michael Beeth, Gillian Roehrig, Margaret J. Mohr-Schroeder, Keith Sheppard, Gregory T. Rushton

Science, Technology, Engineering, and Mathematics (STEM) Education Faculty Publications

Background
Teacher communities of practice, identity, and self-efficacy have been proposed to influence positive teacher outcomes in retention, suggesting all three may be related constructs. Qualitative studies of communities of practice can be difficult to empirically link to identity and self-efficacy in larger samples. In this study, we operationalized teacher communities of practice as specific networks related to teaching content and/or pedagogy. This scalable approach allowed us to quantitatively describe communities of practice and explore statistical relationships with other teacher characteristics. We asked whether these community of practice networks were related to identity and self-efficacy, similar to other conceptualizations of …

Method For Designing Compounds And Compositions Useful For Targeting High Stoichiometric Complexes To Treat Conditions, Including Treatment Of Viruses, Bacteria, And Cancers Having Acquired Drug Resistance, Peixuan Guo, Dan Shu

Pharmaceutical Sciences Faculty Patents

A method is described for the identification o f multi-subunit biocomplex drug targets. The method includes identifying a target that performs a biological function, wherein the target comprises one or more subunits, wherein a minimum number of the one or more subunits is inactivated to inhibit the biological function. The method includes selecting a drug that binds specifically to each subunit of the one or more subunits with a target probability. The method describes a relationship between inhibition efficiency of the drug and total number of the one or more subunits using a binomial distribution, wherein the inhibition efficiency comprises …

The Ear Motif In The Arabidopsis Mads Transcription Factor Agamous-Like 15 Is Not Necessary To Promote Somatic Embryogenesis, Sanjay Joshi, Christian Keller, Sharyn E. Perry

Plant and Soil Sciences Faculty Publications

AGAMOUS-like 15 (AGL15) is a member of the MADS domain family of transcription factors (TFs) that can directly induce and repress target gene expression, and for which promotion of somatic embryogenesis (SE) is positively correlated with accumulation. An ethylene-responsive element binding factor-associated amphiphilic repression (EAR) motif of form LxLxL within the carboxyl-terminal domain of AGL15 was shown to be involved in repression of gene expression. Here, we examine whether AGL15′s ability to repress gene expression is needed to promote SE. While a form of AGL15 where the LxLxL is changed to AxAxA can still promote SE, another form with a …

Brownfield Initiatives And Environmental Justice: Second-Class Cleanups Or Market-Based Equity?, Kirsten H. Engel

Journal of Natural Resources & Environmental Law

No abstract provided.

Learning From Brownfields, Wendy E. Wagner

Journal of Natural Resources & Environmental Law

No abstract provided.

How The Legal System Has Failed The Environmental Justice Movement, Karen Smith

Journal of Natural Resources & Environmental Law

No abstract provided.

Fat And Carbohydrate Interact To Potentiate Food Reward In Healthy Weight But Not In Overweight Or Obesity, Emily E. Perszyk, Zach Hutelin, Jessica Trinh, Arsene Kanyamibwa, Sophie Fromm, Xue S. Davis, Kathryn M. Wall, Kyle D. Flack, Alexandra G. Difeliceantonio, Dana M. Small

Dietetics and Human Nutrition Faculty Publications

Prior work suggests that actual, but not estimated, energy density drives the reinforcing value of food and that energy from fat and carbohydrate can interact to potentiate reward. Here we sought to replicate these findings in an American sample and to determine if the effects are influenced by body mass index (BMI). Thirty participants with healthy weight (HW; BMI 21.92 ± 1.77; M ± SD) and 30 participants with overweight/obesity (OW/OB; BMI 29.42 ± 4.44) rated pictures of common American snacks in 120-kcal portions for liking, familiarity, frequency of consumption, expected satiety, healthiness, energy content, energy density, and price. Participants …

Alternative Community Nutrition Experiential Learning Opportunities For Dietetic Interns During Covid-19, Courtney T. Luecking, Elizabeth Combs, Heather Norman-Burgdolf

Dietetics and Human Nutrition Faculty Publications

In response to the COVID-19 pandemic, collaboration among faculty in the Department of Dietetics and Human Nutrition at the University of Kentucky yielded two, four-week virtual experiential learning opportunities with Cooperative Extension for 19 dietetic interns. Remote experiences focused on development of new programming regarding the role of nutrition in the prevention/management of the most prevalent chronic diseases affecting Kentuckians and translating an existing social marketing program that promotes quality family time through preparation of nutritious, affordable home-cooked meals. Weekly assignments took ~10 hours, included individual and groupwork, and came together to create program packages encompassing commonly used products (e.g., …

Modeling Fate And Transport Of Volatile Organic Compounds (Vocs) Inside Sewer Systems, Mohammadyousef Roghani, Ying Li, Nader Rezaei, Ariel Robinson, Elham Shirazi, Kelly G. Pennell

Civil Engineering Faculty Publications

Hazardous waste site investigations have shown that volatile organic compounds (VOCs) can be transported via sewer pipes and migrate into indoor spaces. Despite field data confirming the presence of this exposure pathway, there is lack of context-based numerical models that provide guidance to characterize and predict VOCs concentration in sewer gas at vapor intrusion sites. Particularly, this poses a challenge when assessing and mitigating risks associated with these exposure pathways. Therefore, a numerical model has been developed to simulate the concentration of VOCs in sewer gas in different stages throughout the sewer lines. The developed model considers various input parameters, …

Southeastern Law Librarian Spring 2021, Seaall

Newsletters

No abstract provided.

Understanding Declining Rates Of Drug Overdose Mortality In Eastern Kentucky, Walsh Center For Rural Health Analysis, University Of Chicago, Center Of Excellence In Rural Health, University Of Kentucky

Center of Excellence in Rural Health Reports

With funding from the Centers for Disease Control and Prevention (CDC) and the National Association of County and City Health Officials (NACCHO), the NORC Walsh Center for Rural Health Analysis and the University of Kentucky Center of Excellence in Rural Health (UK CERH) conducted this study to understand possible factors associated with declining rates of drug overdose mortality in Eastern Kentucky. Several counties in Eastern Kentucky have seen declines in drug overdose mortality rates over the past decade, even as overdose rates have risen in the state of Kentucky as a whole, as well as in the Appalachian regions of …