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Session 2b, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Developing a Vegetation-Based Index of Biotic Integrity for Assessing the Ecological Condition of Wetlands in Kentucky, Tanner Morris and others, Dept of Biological Sciences, EKU, Richmond, KY
• Using Vegetation and Landscape Analysis to Validate a Wetland Rapid Assessment Method for Kentucky's Forested Riparian Wetlands, JohnRyan Polascik and others, Dept of Biological Sciences, EKU, Richmond, KY
• Improving Overall Stream Function Beyond the Channel (Opportunity Meets Necessity), Oakes Routt and Wanda Lawson, Stantec Consulting Services Inc., Louisville, KY
• The Effects of Prescribed Fire Restoration on Amphibian and Reptile Diversity, Robert Knopp and others, Murray State University, Murray, KY …

Session 2a: Developing Post-Incident Risk Communication Guidelines For Intentional Water Contamination Events, Pamela Cupp, Shari R. Veil, Timothy L. Sellnow, H. Dan O'Hair, Nicole Staricek, Katy Anthony, Laura Young, Chike Anyaegbunam, Charles B. Madinger, Anna Goodman Hoover

Kentucky Water Resources Annual Symposium

This panel will discuss a US EPA-funded research project intended to improve risk communication for post-incident decontamination and clearance activities associated with intentional contamination of a water system. The study incorporates two complementary methods conducted in successive phases. The recently-completed first phase included robust case study analyses of risk communication related to recent and significant contamination incidents. The second phase, which is currently underway, will identify ways in which disparate stakeholder groups in a metropolitan area differentially perceive risk and subsequent risk communication efforts.

Session 1d, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Subwatershed Clustering Based on Geomorphic and Human Induced Landscape Modifications: The Commonwealth of Kentucky, Brian Lee and others, Dept of Landscape Architecture, UK
• Imperviousness and Greenness: Extracting Watershed Metrics from Bi-Temporal, Multispectral Aerial Imagery and LiDAR, Demetrio Zourarakis, Commonwealth Office of Technology, Frankfort, KY
• Landscape Scale Assessment of Soil Moisture Variability using Auxiliary Sensing Technologies and Multivariate Geostatistics, Carla Landrum and others, Dept of Plant and Soil Sciences, UK
• Field -Scale Bromide Leaching as Affected by Land Use and Rainfall Characteristics, Yang Yang, Dept of Plant and Soil Science, UK

Session 1c, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Engaging Partners in the Cane Rune Watershed, Carol Hanley and others, College of Agriculture, UK
• Water Quality Monitoring Results from the McConnell Springs Stormwater Quality Wetland Pond and Gainseway Pond Retrofit Project, David Price and Susan Plueger, Lexington-Fayette County Government, Lexington, KY
• Hydrologic Characterization of a Tree- and Shrub-Vegetated Rain Garden in Central Kentucky, John McMaine and Carmen Agouridis, Dept Biosystems and Agricultural Engineering, UK
• Watershed Based Planning in the Urban Wolf Run Watershed, Steven Evans, Third Rock Consultants, LLC, Lexington, KY
• Estimating Load Reduction Costs for Assessing Stormwater Best Management Practice (BMP) Feasibility: A Case …

Session 1b, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Flowing Onward: Mapping New Program Directions for the Kentucky Geological Survey's Water Resources Section, Charles Taylor, KGS, UK
• The Presence of 17-β Estradiol and Fluoroquinolones in Kentucky's Surface Waters, E. Glynn Beck and others, KGS, Henderson, KY
• Mapping Karst Sinkholes Using LiDAR - A Pilot Study in Floyds Fork Watershed, Central Kentucky, Patrick Taylor and others, KGS, UK
• Changes in the Kentucky Groundwater Data Repository Search Engines, Bart Davidson, KGS, UK
• Groundwater Discharge at the Kentucky Horse Park KWIS Station, James Currens and Mike Farwell, KGS, UK

Session 1a, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Development and Testing of a New Phosphorus Index for Kentucky, Carl Bolster and others, USDA-ARS, Bowling Green, KY
• The New Kentucky Nitrogen and Phosphorus Risk Assessment Tool to Protect Water Quality, Tibor Horvath and others, USDA-NRCS, Lexington, KY
• Herbicide Transport Within Shallow Karst Groundwater on Kentucky's Pennyroyal Plateau Beneath Row Crop Agriculture, Chris Groves and others, Hoffman Environmental Research Institute, WKU, Bowling Green, KY
• Groundwater Tracing in the West Pennyrile Karst Region, Robert Blair and Jessica Moore, Kentucky Division of Water, Frankfort, KY

Proceedings Of 2013 Kentucky Water Resources Annual Symposium, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

This symposium was planned and conducted as a part of the state water resources research institute annual program that is supported by Grant/Cooperative Agreement Number G11AP20081 from the United States Geological Survey. The contents of this proceedings document and the views and conclusions presented at the symposium are solely the responsibility of the individual authors and presenters and do not necessarily represent the official views of the USGS or of the symposium organizers and sponsors. This publication is produced with the understanding that the United States Government is authorized to reproduce and distribute reprints for government purposes.

Sensory Systems And Environmental Change On Behavior During Social Interactions, Sonya M. Bierbower, J. Nadolski, Robin L. Cooper

Biology Faculty Publications

The impact of environmental conditions for transmitting sensory cues and the ability of crayfish to utilize olfaction and vision were examined in regards to social interactive behavior. The duration and intensity of interactions were examined for conspecific crayfish with different sensory abilities. Normally, vision and chemosensory have roles in agonistic communication of Procambarus clarkii; however, for the blind cave crayfish (Orconectes australis packardi), that lack visual capabilities, olfaction is assumed to be the primary sensory modality. To test this, we paired conspecifics in water and out of water in the presence and absence of white light to …

Radiative Cooling In Collisionally Ionized And Photoionized Plasmas, Matt Lykins, Gary J. Ferland, Ryan L. Porter, Peter A. M. Van Hoof, R. J. R. Williams, Orly Gnat

Physics and Astronomy Faculty Publications

We discuss recent improvements in the calculation of the radiative cooling in both collisionally ionized and photoionized plasmas. We are extending the spectral simulation code CLOUDY so that as much as possible of the underlying atomic data are taken from external data bases, some created by others and some developed by the CLOUDY team. This paper focuses on recent changes in the treatment of many stages of ionization of iron, and discusses its extensions to other elements. The H- and He-like ions are treated in the isoelectronic approach described previously. Fe II is a special case treated with a large …

Physicochemical Characterization And Aerosol Dispersion Performance Of Organic Solution Advanced Spray-Dried Cyclosporine A Multifunctional Particles For Dry Powder Inhalation Aerosol Delivery, Xiao Wu, Weifen Zhang, Don Hayes Jr., Heidi M. Mansour

Pharmaceutical Sciences Faculty Publications

In this systematic and comprehensive study, inhalation powders of the polypeptide immunosuppressant drug - cyclosporine A - for lung delivery as dry powder inhalers (DPIs) were successfully designed, developed, and optimized. Several spray drying pump rates were rationally chosen. Comprehensive physicochemical characterization and imaging was carried out using scanning electron microscopy, hot-stage microscopy, differential scanning calorimetry, powder X-ray diffraction, Karl Fischer titration, laser size diffraction, and gravimetric vapor sorption. Aerosol dispersion performance was conducted using a next generation impactor with a Food and Drug Administration-approved DPI device. These DPIs displayed excellent aerosol dispersion performance with high values in emitted dose, …

Population Impacts Of Wolbachia On Aedes Albopictus, James W. Mains, Corey L. Brelsfoard, Philip R. Crain, Yunxin Huang, Stephen L. Dobson

Entomology Faculty Publications

Prior studies have demonstrated that Wolbachia, a commonly occurring bacterium capable of manipulating host reproduction, can affect life history traits in insect hosts, which in turn can have population-level effects. Effects on hosts at the individual level are predicted to impact population dynamics, but the latter has not been examined empirically. Here, we describe a biological model system based on Aedes albopictus (Asian tiger mosquito) that allows for measurement of population dynamics, which has not been accomplished in prior field trials or laboratory designs. The results demonstrate the studied populations to be robust and allow for persistent, closed populations with …

Studies Of Ngc 6720 With Calibrated Hst/Wfc3 Emission-Line Filter Images. Ii. Physical Conditions, C. R. O'Dell, Gary J. Ferland, W. J. Henney, M. Peimbert

Physics and Astronomy Faculty Publications

We have performed a detailed analysis of the electron temperature and density in the Ring Nebula using the calibrated Hubble Space Telescope WFC3 images described in the preceding paper. The electron temperature (T_e) determined from [NII] and [O III] rises slightly and monotonically toward the central star. The observed equivalent width (EW) in the central region indicates that T_e rises as high as 13,000 K. In contrast, the low EWs in the outer regions are largely due to scattered diffuse Galactic radiation by dust. The images allowed determination of unprecedented small-scale variations in T_e. …

Simultaneous Measurement Of Deep Tissue Blood Flow And Oxygenation Using Noncontact Diffuse Correlation Spectroscopy Flow-Oximeter, Ting Li, Yu Lin, Yu Shang, Lian He, Chong Huang, Margaret M. Szabunio, Guoqiang Yu

Biomedical Engineering Faculty Publications

We report a novel noncontact diffuse correlation spectroscopy flow-oximeter for simultaneous quantification of relative changes in tissue blood flow (rBF) and oxygenation (Δ[oxygenation]). The noncontact probe was compared against a contact probe in tissue-like phantoms and forearm muscles (n = 10), and the dynamic trends in both rBF and Δ[oxygenation] were found to be highly correlated. However, the magnitudes of Δ[oxygenation] measured by the two probes were significantly different. Monte Carlo simulations and phantom experiments revealed that the arm curvature resulted in a significant underestimation (~-20%) for the noncontact measurements in Δ[ …

Studies Of Ngc 6720 With Calibrated Hst/Wfc3 Emission-Line Filter Images. I. Structure And Evolution, C. R. O'Dell, Gary J. Ferland, W. J. Henney, M. Peimbert

Physics and Astronomy Faculty Publications

We have performed a detailed analysis of the Ring Nebula (NGC 6720) using Hubble Space Telescope WFC3 images and derived a new three-dimensional model. Existing high spectral resolution spectra played an important supplementary role in our modeling. It is shown that the Main Ring of the nebula is an ionization-bounded irregular non-symmetric disk with a central cavity and perpendicular extended lobes pointed almost toward the observer. The faint outer halos are determined to be fossil radiation, i.e., radiation from gas ionized in an earlier stage of the nebula when it was not ionization bounded. The narrowband WFC3 filters that isolate …

Photo Highlights From The 33rd Kentucky Alfalfa Conference, Krista Cotton

Kentucky Alfalfa and Stored Forage Conference

No abstract provided.

Finishing Beef On Alfalfa, Todd Powell

Kentucky Alfalfa and Stored Forage Conference

Powell Farms started in 1996 with 15 acres of Alfalfa hay intended for cow/calf feed. A neighbor and his friends bought every bale that year. Over the next 14 years the only alfalfa hay our cows got to eat was when a cutting got wet and was rolled. As with any business when the economy starts to take a downward trend, it is wise to start looking for new and innovative ways to market your product.

Making And Marketing Hay For The Horse Industry, Todd Clark

Kentucky Alfalfa and Stored Forage Conference

No abstract provided.

Fertilizer: How Much Is In Each Bale?, Dennis Hancock

Kentucky Alfalfa and Stored Forage Conference

What do you see when you look at a bale? Certainly, many would say it is a source of feed for our livestock. Others see a commodity that is sold to their customers. These are the most important aspects of any forage. But, there is one other intrinsic value worth noting… its nutrient content. In a sense, it is a bale of fertilizer.

Our Experience With Roundup Ready Alfalfa, Clayton Geralds

Kentucky Alfalfa and Stored Forage Conference

We raise approximately 500 acres of alfalfa with approximately 175 seeded to Roundup Ready varieties. We established our first field in 2006 and a second in 2007. Roundup Ready alfalfa was not available for additional seedings until 2011. We have seeded over 100 additional acres in 2011 and 2012.

Key To Success When Harvesting Alfalfa As Baleage, S. Ray Smith

Kentucky Alfalfa and Stored Forage Conference

Alfalfa is an excellent forage for high-producing cows and universally considered one of the highest-quality forages. Cows efficiently use the high levels of protein, calcium and high-quality fiber in alfalfa for producing milk and meat. The palatability of alfalfa is high, especially when the leaves are maintained during harvest. Typically, cows will eat more alfalfa than grass because the fiber content is usually lower in alfalfa. Harvesting alfalfa as baleage vs. hay greatly improves the chances maintaining high quality because there is less leaf loss and less loss of soluble carbohydrates. The most important factor is harvesting high quality alfalfa …

Alfalfa For Grazing, Garry D. Lacefield

Kentucky Alfalfa and Stored Forage Conference

High grain prices, increasing nitrogen prices, droughts, need for higher quality pasture plants and improved alfalfa varieties have all contributed to a greater interest in and opportunity for alfalfa as a grazing crop.

Foreword And Recipients Of Kentucky Alfalfa Awards [2013], Garry D. Lacefield, Christi L. Forsythe

Kentucky Alfalfa and Stored Forage Conference

No abstract provided.

Clobazam Therapeutic Drug Monitoring: A Comprehensive Review Of The Literature With Proposals To Improve Future Studies, Jose De Leon, Edoardo Spina, Francisco J. Diaz

Psychiatry Faculty Publications

Background: Clobazam was recently approved for Lennox–Gastaut syndrome in the United States. There is no published review article focused on clobazam therapeutic drug monitoring (TDM) in English.

Methods: More than 200 clobazam articles identified by a PubMed search were carefully reviewed for information on clobazam pharmacokinetics. Clobazam is mainly metabolized by a cytochrome P450 (CYP) isoenzyme, CYP3A4, to its active metabolite, N-desmethylclobazam. Then, N-desmethylclobazam is mainly metabolized by CYP2C19 unless the individual has no CYP2C19 activity [poor metabolizer (PM)].

Results: Using a mechanistic approach to reinterpret the published findings of steady-state TDM and single-dosing pharmacokinetic studies, 4 different serum clobazam …

Class Of Ferromagnetic Semiconductors, Larysa Shlyk, Sergiy A. Kryukov, Lance E. De Long, Barbara Schüpp-Niewa, Rainer Niewa

Physics and Astronomy Faculty Patents

Single crystal and polycrystal oxoruthenates having the generalized compositions (Ba_z,Sr_1−z)Fe_xCo_yRu_6−(x+y)O₁₁ (1≦(x+y)≦5; 0≦z≦1) and (Ba,Sr)M_2±xRu_4∓xO₁₁ (M=Fe,Co) belong to a novel class of ferromagnetic semiconductors with applications in spin-based field effect transistors, spin-based light emitting diodes, and magnetic random access memories.

Activation Of Thromboxane A2 Receptor (Tp) Increases The Expression Of Monocyte Chemoattractant Protein -1 (Mcp-1)/Chemokine (C-C Motif) Ligand 2 (Ccl2) And Recruits Macrophages To Promote Invasion Of Lung Cancer Cells, Xiuling Li, Hsin-Hsiung Tai

Pharmaceutical Sciences Faculty Publications

Thromboxane synthase (TXAS) and thromboxane A₂ receptor (TP), two critical components for thromboxane A₂ (TXA₂) signaling, have been suggested to be involved in cancer invasion and metastasis. However, the mechanisms by which TXA₂ promotes these processes are still unclear. Here we show that TXA₂ mimetic, I-BOP, induced monocyte chemoattractant protein -1(MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) expression at both mRNA and protein levels in human lung adenocarcinoma A549 cells stably over-expressing TP receptor α isoform (A549-TPα). The induction of MCP-1 was also found in other lung cancer cells H157 and H460 that express relatively …

Design, Physicochemical Characterization, And Optimization Of Organic Solution Advanced Spray-Dried Inhalable Dipalmitoylphosphatidylcholine (Dppc) And Dipalmitoylphosphatidylethanolamine Poly(Ethylene Glycol) (Dppe-Peg) Microparticles And Nanoparticles For Targeted Respiratory Nanomedicine Delivery As Dry Powder Inhalation Aerosols, Samantha Ann Meenach, Frederick G. Vogt, Kimberly W. Anderson, J. Zach Hilt, Ronald C. Mcgarry, Heidi M. Mansour

Pharmaceutical Sciences Faculty Publications

Novel advanced spray-dried and co-spray-dried inhalable lung surfactant-mimic phospholipid and poly(ethylene glycol) (PEG)ylated lipopolymers as microparticulate/nanoparticulate dry powders of biodegradable biocompatible lipopolymers were rationally formulated via an organic solution advanced spray-drying process in closed mode using various phospholipid formulations and rationally chosen spray-drying pump rates. Ratios of dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylethanolamine PEG (DPPE-PEG) with varying PEG lengths were mixed in a dilute methanol solution. Scanning electron microscopy images showed the smooth, spherical particle morphology of the inhalable particles. The size of the particles was statistically analyzed using the scanning electron micrographs and SigmaScan® software and were determined to be 600 …

Risk Score Modeling Of Multiple Gene To Gene Interactions Using Aggregated-Multifactor Dimensionality Reduction, Hongying Dai, Richard J. Charnigo, Mara L. Becker, J. Steven Leeder, Alison A. Motsinger-Reif

Statistics Faculty Publications

BACKGROUND: Multifactor Dimensionality Reduction (MDR) has been widely applied to detect gene-gene (GxG) interactions associated with complex diseases. Existing MDR methods summarize disease risk by a dichotomous predisposing model (high-risk/low-risk) from one optimal GxG interaction, which does not take the accumulated effects from multiple GxG interactions into account.

RESULTS: We propose an Aggregated-Multifactor Dimensionality Reduction (A-MDR) method that exhaustively searches for and detects significant GxG interactions to generate an epistasis enriched gene network. An aggregated epistasis enriched risk score, which takes into account multiple GxG interactions simultaneously, replaces the dichotomous predisposing risk variable and provides higher resolution in the quantification …

A Neural Network Model To Translate Brain Developmental Events Across Mammalian Species, Radhakrishnan Nagarajan, Jeffrey N. Jonkman

Biostatistics Faculty Publications

Translating the timing of brain developmental events across mammalian species using suitable models has provided unprecedented insights into neural development and evolution. More importantly, these models can prove to be useful abstractions and predict unknown events across species from known empirical event timing data retrieved from published literature. Such predictions can be especially useful since the distribution of the event timing data is skewed with a majority of events documented only across a few selected species. The present study investigates the choice of single hidden layer feed-forward neural networks (FFNN) for predicting the unknown events from the empirical data. A …

Error Bounds For The Lanczos Methods For Approximating Matrix Exponentials, Qiang Ye

Mathematics Faculty Publications

In this paper, we present new error bounds for the Lanczos method and the shift-and-invert Lanczos method for computing e−^τAv for a large sparse symmetric positive semidefinite matrix A. Compared with the existing error analysis for these methods, our bounds relate the convergence to the condition numbers of the matrix that generates the Krylov subspace. In particular, we show that the Lanczos method will converge rapidly if the matrix A is well-conditioned, regardless of what the norm of τA is. Numerical examples are given to demonstrate the theoretical bounds.

Comparison Of Models For Mixture Transport Properties For Numerical Simulations Of Ablative Heat-Shields, Hicham Alkandry, Iain D. Boyd, Alexandre Martin

Mechanical Engineering Faculty Publications

The goal of this study is to evaluate the effects of different models for calculating the mixture transport properties on flowfield predictions of ablative heat-shields. The Stardust sample return capsule at four different trajectory conditions is used as a test case for this study. In the first part of the study, the results predicted using Wilke's mixing rule with species viscosities calculated using Blottner's curve fits and species thermal conductivities determined using Eucken's relation are compared to the results obtained using Gupta's mixing rule with collision cross-section (CCS) data. The Wilke/Blottner/Eucken model overpredicts the heat transfer to the surface relative …