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The Effects Of Myelin On Macrophage Activation Are Phenotypic Specific Via Cpla2 In The Context Of Spinal Cord Injury Inflammation, Timothy J. Kopper, Bei Zhang, William M. Bailey, Kara E. Bethel, John C. Gensel Mar 2021

The Effects Of Myelin On Macrophage Activation Are Phenotypic Specific Via Cpla2 In The Context Of Spinal Cord Injury Inflammation, Timothy J. Kopper, Bei Zhang, William M. Bailey, Kara E. Bethel, John C. Gensel

Physiology Faculty Publications

Spinal cord injury (SCI) produces chronic, pro-inflammatory macrophage activation that impairs recovery. The mechanisms driving this chronic inflammation are not well understood. Here, we detail the effects of myelin debris on macrophage physiology and demonstrate a novel, activation state-dependent role for cytosolic phospholipase-A2 (cPLA2) in myelin-mediated potentiation of pro-inflammatory macrophage activation. We hypothesized that cPLA2 and myelin debris are key mediators of persistent pro-inflammatory macrophage responses after SCI. To test this, we examined spinal cord tissue 28-days after thoracic contusion SCI in 3-month-old female mice and observed both cPLA2 activation and intracellular accumulation of lipid-rich myelin …


The Trash Trade: Foreign Hazardous Waste As An Object Of Commerce In Chemical Waste Management, Inc. V. Templet, Amy E. Barto Mar 2021

The Trash Trade: Foreign Hazardous Waste As An Object Of Commerce In Chemical Waste Management, Inc. V. Templet, Amy E. Barto

Journal of Natural Resources & Environmental Law

No abstract provided.


Acid Rain: The Use Of Diplomacy, Policy And The Courts To Solve A Transboundary Pollution Problem, Shawn M. Rosso Mar 2021

Acid Rain: The Use Of Diplomacy, Policy And The Courts To Solve A Transboundary Pollution Problem, Shawn M. Rosso

Journal of Natural Resources & Environmental Law

No abstract provided.


Debt-For-Nature Swaps In Brazil: Response To World Pressure To Protect The Amazon, David Allen Reisman Mar 2021

Debt-For-Nature Swaps In Brazil: Response To World Pressure To Protect The Amazon, David Allen Reisman

Journal of Natural Resources & Environmental Law

No abstract provided.


The Norms Of Nuclear Accidents After Chernobyl, Melanie L. Oxhorn Mar 2021

The Norms Of Nuclear Accidents After Chernobyl, Melanie L. Oxhorn

Journal of Natural Resources & Environmental Law

No abstract provided.


The Earth Summit And Limits On Carbon Dioxide Emissions: Reading Between The Lines, James D. Desmond Mar 2021

The Earth Summit And Limits On Carbon Dioxide Emissions: Reading Between The Lines, James D. Desmond

Journal of Natural Resources & Environmental Law

No abstract provided.


The Jurisprudence Of The 1992 Rio Declaration On Environment And Development: A Law, Science, And Policy Explication Of Certain Aspects Of The United Nations Conference On Environment And Development, John Batt, David C. Short Mar 2021

The Jurisprudence Of The 1992 Rio Declaration On Environment And Development: A Law, Science, And Policy Explication Of Certain Aspects Of The United Nations Conference On Environment And Development, John Batt, David C. Short

Journal of Natural Resources & Environmental Law

No abstract provided.


Legal Bases For Securing The Integrity Of The Earth-Space Environment, Myres S. Mcdougal Mar 2021

Legal Bases For Securing The Integrity Of The Earth-Space Environment, Myres S. Mcdougal

Journal of Natural Resources & Environmental Law

No abstract provided.


Standard Of Review Under The Toxic Substances Control Act: Corrosion Proof Fittings V. E.P.A., Joyce Merritt Mar 2021

Standard Of Review Under The Toxic Substances Control Act: Corrosion Proof Fittings V. E.P.A., Joyce Merritt

Journal of Natural Resources & Environmental Law

No abstract provided.


After 3550 Stevens Creek Associates V. Barclays Bank: Will Response Costs For Asbestos Removal Be Permitted Under Cercla?, Jennifer G. Marwitz Mar 2021

After 3550 Stevens Creek Associates V. Barclays Bank: Will Response Costs For Asbestos Removal Be Permitted Under Cercla?, Jennifer G. Marwitz

Journal of Natural Resources & Environmental Law

No abstract provided.


The Koko Incident: Developing International Norms For The Transboundary Movement Of Hazardous Waste, Sylvia F. Liu Mar 2021

The Koko Incident: Developing International Norms For The Transboundary Movement Of Hazardous Waste, Sylvia F. Liu

Journal of Natural Resources & Environmental Law

No abstract provided.


Jurisdiction Over Water Quality On Native American Lands, Charlotte Uram, Mary J. Decker Mar 2021

Jurisdiction Over Water Quality On Native American Lands, Charlotte Uram, Mary J. Decker

Journal of Natural Resources & Environmental Law

No abstract provided.


Indices To Volumes 5 - 7, Journal Of Mineral Law & Policy Mar 2021

Indices To Volumes 5 - 7, Journal Of Mineral Law & Policy

Journal of Natural Resources & Environmental Law

No abstract provided.


Environmental Law As Corporate Law: Parent-Subsidiary Liability Under Cercla And The Kayser-Roth Aftermath, Douglas A. Henderson Mar 2021

Environmental Law As Corporate Law: Parent-Subsidiary Liability Under Cercla And The Kayser-Roth Aftermath, Douglas A. Henderson

Journal of Natural Resources & Environmental Law

No abstract provided.


Mining Waste And The Resource Conservation And Recovery Act: An Overview, Glenn C. Van Bever Mar 2021

Mining Waste And The Resource Conservation And Recovery Act: An Overview, Glenn C. Van Bever

Journal of Natural Resources & Environmental Law

No abstract provided.


The Challenge Of Latent Physical Effects Of Toxic Substances: The Next Step In The Evolution Of Toxic Torts, Kathleen A. O'Nan Mar 2021

The Challenge Of Latent Physical Effects Of Toxic Substances: The Next Step In The Evolution Of Toxic Torts, Kathleen A. O'Nan

Journal of Natural Resources & Environmental Law

No abstract provided.


Alternative Minimum Tax: The Percentage Depletion Tax Preference For Investments In Natural Resources After Hill V. United States, Wade C. Lawson Mar 2021

Alternative Minimum Tax: The Percentage Depletion Tax Preference For Investments In Natural Resources After Hill V. United States, Wade C. Lawson

Journal of Natural Resources & Environmental Law

No abstract provided.


Competing Ownership Claims And Environmental Concerns In Coalbed Methane Gas Development In The Appalachian Basin, Elizabeth A. Mcclanahan Mar 2021

Competing Ownership Claims And Environmental Concerns In Coalbed Methane Gas Development In The Appalachian Basin, Elizabeth A. Mcclanahan

Journal of Natural Resources & Environmental Law

No abstract provided.


National Institute Of Occupational Safety And Health: Limits Of Authority In Rulemaking Under The Federal Mine Safety And Health Act Of 1977, Michael T. Heenan, C. Gregory Ruffenach Mar 2021

National Institute Of Occupational Safety And Health: Limits Of Authority In Rulemaking Under The Federal Mine Safety And Health Act Of 1977, Michael T. Heenan, C. Gregory Ruffenach

Journal of Natural Resources & Environmental Law

No abstract provided.


Table Of Contents For Volume 7, Issue 2, Journal Of Mineral Law & Policy Mar 2021

Table Of Contents For Volume 7, Issue 2, Journal Of Mineral Law & Policy

Journal of Natural Resources & Environmental Law

No abstract provided.


"Te Pee" As In Taxpayer: Tribal Severance Taxes--Canvassing The Reservation-Do Tribes Have The Power To Impose Severance Taxes On Minerals Extracted On Non-Indian Fee Lands Within The Reservation?, Michael Layne Carrico Mar 2021

"Te Pee" As In Taxpayer: Tribal Severance Taxes--Canvassing The Reservation-Do Tribes Have The Power To Impose Severance Taxes On Minerals Extracted On Non-Indian Fee Lands Within The Reservation?, Michael Layne Carrico

Journal of Natural Resources & Environmental Law

No abstract provided.


Self-Mined Coal Used As Fuel And The Black Lung Coal Tax, Mark F. Sommer Mar 2021

Self-Mined Coal Used As Fuel And The Black Lung Coal Tax, Mark F. Sommer

Journal of Natural Resources & Environmental Law

No abstract provided.


Kentucky's New Nuisance Statute, John S. Palmore Mar 2021

Kentucky's New Nuisance Statute, John S. Palmore

Journal of Natural Resources & Environmental Law

No abstract provided.


Abandonment Of Contaminated Property Under The Bankruptcy Code--From Midlantic To In Re Smith Douglas, What Next?, Brian Cumbo Mar 2021

Abandonment Of Contaminated Property Under The Bankruptcy Code--From Midlantic To In Re Smith Douglas, What Next?, Brian Cumbo

Journal of Natural Resources & Environmental Law

No abstract provided.


Retroactive Liability For Clean-Up Of Hazardous Waste In Atlas V. United States: The Nuclear Industry's Failed Attempt To Make The Government Pay, Mary Boaz Mar 2021

Retroactive Liability For Clean-Up Of Hazardous Waste In Atlas V. United States: The Nuclear Industry's Failed Attempt To Make The Government Pay, Mary Boaz

Journal of Natural Resources & Environmental Law

No abstract provided.


Dilution Is Not The Solution, Linda Stowers Mar 2021

Dilution Is Not The Solution, Linda Stowers

Journal of Natural Resources & Environmental Law

No abstract provided.


Evolving Rico Issues For The Environmental/Natural Resources Practitioner, Alfred L. Buchanan Mar 2021

Evolving Rico Issues For The Environmental/Natural Resources Practitioner, Alfred L. Buchanan

Journal of Natural Resources & Environmental Law

No abstract provided.


Edf V. Epa: The Dispute Surrounding Mining Waste Regulation Under The Bevill Amendment, Yvette R. Hurt Mar 2021

Edf V. Epa: The Dispute Surrounding Mining Waste Regulation Under The Bevill Amendment, Yvette R. Hurt

Journal of Natural Resources & Environmental Law

No abstract provided.


Surface Use And Damages Statutes: "Cloud"Ed Constitutionality, Stacey L. Graus Mar 2021

Surface Use And Damages Statutes: "Cloud"Ed Constitutionality, Stacey L. Graus

Journal of Natural Resources & Environmental Law

No abstract provided.


Inequitable Valuation In Regulatory Takings Cases: Compensation That "Goes Too Far", Lori C. Hudson Mar 2021

Inequitable Valuation In Regulatory Takings Cases: Compensation That "Goes Too Far", Lori C. Hudson

Journal of Natural Resources & Environmental Law

No abstract provided.