Digital Commons Network^™

Regulatory Takings: When Is Enough, Enough?, Jacqueline Kerry Heyman

Journal of Natural Resources & Environmental Law

No abstract provided.

A Dark And Bloody Battle Ground: Wetland Preservation In Kentucky, Jane Marie Watts

Journal of Natural Resources & Environmental Law

No abstract provided.

Landmarks And City Hall: How Historic Preservation Contributes To Municipal Government, Frank B. Gilbert

Journal of Natural Resources & Environmental Law

No abstract provided.

The Rcra Citizen Suit Provision And The Private Remedy Of Restitution After Kfc Western, Inc. V. Meghrig And Furrer V. Brown: Reasonable Minds May Differ, J. Thomas Blaine Lewis

Journal of Natural Resources & Environmental Law

No abstract provided.

National Solid Wastes Management Association V. Meyer: The Dormant Commerce Clause Claims Another Environmental Victim, Eric Anthony Braun

Journal of Natural Resources & Environmental Law

No abstract provided.

Vicarious Liability For Mine Safety And Health Violations, William K. Doran

Journal of Natural Resources & Environmental Law

No abstract provided.

Reclamation And Groundwater Restoration In The Uranium Milling Industry: An Assessment Of Umtrca, Title Ii, John D. Collins

Journal of Natural Resources & Environmental Law

No abstract provided.

Shared Management Of Reasonable Risk: Implications For Environmental Assessment And Monitoring, Vern R. Walker

Journal of Natural Resources & Environmental Law

No abstract provided.

Table Of Contents For Volume 11, Issue 1, Journal Of Natural Resources & Environmental Law

Journal of Natural Resources & Environmental Law

No abstract provided.

States' Powerful New Shield To Guard Water Resources: Pud No. 1 Of Jefferson County V. Washington Department Of Ecology, W. Blaine Early Iii

Journal of Natural Resources & Environmental Law

No abstract provided.

Kentucky's Efforts To Protect Its Groundwater: Uniqueness And Uniformity Among The States, Melanie S. Marrs

Journal of Natural Resources & Environmental Law

No abstract provided.

Federal Groundwater Regulation And Policy: Improvements Under The Horizon?, Allyn G. Turner

Journal of Natural Resources & Environmental Law

No abstract provided.

The Storm Water Regulatory Scheme: Washing An Industry Down The Drain?, Kathy G. Beckett, Becky L. Jacobs

Journal of Natural Resources & Environmental Law

No abstract provided.

Acid Mine Drainage: Common Law, Smcra, And The Clean Water Act, Caroline Henrich

Journal of Natural Resources & Environmental Law

No abstract provided.

Acid Mine Drainage: Balancing Environmental Protection And Mining Realities, Barkley J. Sturgill Jr., Kim Brown Poland

Journal of Natural Resources & Environmental Law

No abstract provided.

Regulating For The Long Term: Smcra And Acid Mine Drainage, Courtney W. Shea

Journal of Natural Resources & Environmental Law

No abstract provided.

Let Us Hope For Smart Fish: A Clean Water Act Practitioner's Search For Ratchet Down, W. Henry Graddy Iv

Journal of Natural Resources & Environmental Law

No abstract provided.

Searches By Environmental Protection Agencies: When Is A Warrant Necessary?, David Sparks

Journal of Natural Resources & Environmental Law

No abstract provided.

Regulation Of Municipal Incinerator Ash: City Of Chicago V. Environmental Defense Fund, Inc., Tiffany D. Gabehart

Journal of Natural Resources & Environmental Law

No abstract provided.

Ozone Depletion, Developing Countries, And Human Rights: Seeking Better Ground On Which To Fight For Protection Of The Ozone Layer, Victor Williams

Journal of Natural Resources & Environmental Law

No abstract provided.

Unanticipated Environmental Costs In Construction Contracts: The Differing Site Conditions Clause As A Risk Allocation Tool, Steven C. Sanders

Journal of Natural Resources & Environmental Law

No abstract provided.

Strict Liability And Sick Building Syndrome: Defining A Building As A Product Under Restatement (Second) Of Torts, Section 402a, David Reisman

Journal of Natural Resources & Environmental Law

No abstract provided.

The Economics Of Pollution Taxes, Howard Gensler

Journal of Natural Resources & Environmental Law

No abstract provided.

Nmr Methods For Determining Lipid Turnover Via Stable Isotope Resolved Metabolomics, Penghui Lin, Li Dai, Daniel R. Crooks, Leonard M. Neckers, Richard M. Higashi, Teresa W.-M. Fan, Andrew N. Lane

Center for Environmental and Systems Biochemistry Faculty Publications

Lipids comprise diverse classes of compounds that are important for the structure and properties of membranes, as high-energy fuel sources and as signaling molecules. Therefore, the turnover rates of these varied classes of lipids are fundamental to cellular function. However, their enormous chemical diversity and dynamic range in cells makes detailed analysis very complex. Furthermore, although stable isotope tracers enable the determination of synthesis and degradation of complex lipids, the numbers of distinguishable molecules increase enormously, which exacerbates the problem. Although LC-MS-MS (Liquid Chromatography-Tandem Mass Spectrometry) is the standard for lipidomics, NMR can add value in global lipid analysis and …

Mathematical Modeling Of The Candida Albicans Yeast To Hyphal Transition Reveals Novel Control Strategies, David J. Wooten, Jorge Gómez Tejeda Zañudo, David Murrugarra, Austin M. Perry, Anna Dongari-Bagtzoglou, Reinhard Laubenbacher, Clarissa J. Nobile, Réka Albert

Mathematics Faculty Publications

Candida albicans, an opportunistic fungal pathogen, is a significant cause of human infections, particularly in immunocompromised individuals. Phenotypic plasticity between two morphological phenotypes, yeast and hyphae, is a key mechanism by which C. albicans can thrive in many microenvironments and cause disease in the host. Understanding the decision points and key driver genes controlling this important transition and how these genes respond to different environmental signals is critical to understanding how C. albicans causes infections in the host. Here we build and analyze a Boolean dynamical model of the C. albicans yeast to hyphal transition, integrating …

Prevalence And Characteristics Of Self-Reported Hypothyroidism And Its Association With Nonorgan-Specific Manifestations In Us Sarcoidosis Patients: A Nationwide Registry Study, Bashar N. Alzghoul, Farah N. Amer, Diana Barb, Ayoub Innabi, Mamoun T. Mardini, Chen Bai, Bara Alzghoul, Tamara Al-Hakim, Noopur Singh, Mindy Buchanan, Leslie Serchuck, Diana Gomez Manjarres, Whitney W. Woodmansee, Lisa A. Maier, Divya C. Patel

Internal Medicine Faculty Publications

Little is known about the prevalence, clinical characteristics and impact of hypothyroidism in patients with sarcoidosis. We aimed to determine the prevalence and clinical features of hypothyroidism and its relation to organ involvement and other clinical manifestations in patients with sarcoidosis.

We conducted a national registry-based study investigating 3835 respondents to the Sarcoidosis Advanced Registry for Cures Questionnaire between June 2014 and August 2019. This registry is based on a self-reported, web-based questionnaire that provides data related to demographics, diagnostics, sarcoidosis manifestations and treatment. We compared sarcoidosis patients with and without self-reported hypothyroidism. We used multivariable logistic regression and adjusted …

Coconut Inflorescence Sap Enhances Exercise Performance And Plasma Antioxidant Status In Young Active Men, Ashish Joseph, Svenia P. Jose, Bintu T. Kalyan, Renny R. Mammen, I. M. Krishnakumar, Bradley S. Fleenor, Ratheesh Mohan

Kinesiology and Health Promotion Faculty Publications

Purpose
Nutrition has been increasingly recognized as a key component to optimal sports performance. Though several botanical agents have been reported to possess ergogenic potential, there exists a great interest for tasty and safe natural substances as performance boosters. In the present contribution, the ergogenic potential of a novel powder form of coconut inflorescence sap (CSP) was investigated for the first time.

Method
Out of the fourteen participants recruited, twelve recreationally active men completed the single-blinded, placebo-controlled, crossover study for 8 weeks. Running based anaerobic sprint test (RAST) and 2.4 km running test were performed as anaerobic and aerobic tests, …

Early Satellite Cell Communication Creates A Permissive Environment For Long-Term Muscle Growth, Kevin A. Murach, Bailey D. Peck, Robert A. Policastro, Ivan J. Vechetti Jr., Douglas W. Van Pelt, Cory M. Dungan, Lance T. Denes, Xu Fu, Camille R. Brightwell, Gabriel E. Zentner, Esther E. Dupont-Versteegden, Christopher I. Richards, Jeramiah J. Smith, Christopher S. Fry, John J. Mccarthy, Charlotte A. Peterson

Center for Muscle Biology Faculty Publications

Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking, satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show satellite cells communicate with other cells in skeletal muscle during mechanical overload. Early satellite cell EV communication primes the muscle milieu for proper long-term extracellular matrix (ECM) deposition and is sufficient to support sustained hypertrophy in adult mice, even in the absence of fusion to muscle fibers. Satellite cells modulate chemokine gene expression across cell types within the first few days of loading, and EV delivery of miR-206 to fibrogenic cells represses Wisp1 expression required …

Clinical Geography: A Proposal To Embrace Space, Place And Wellbeing Through Person-Centered Practice, Jessica M. Finlay, Graham D. Rowles

Graduate Center for Gerontology Faculty Publications

This essay envisions how geography can operationalize nuanced understandings of space and place to enrich the lives of individuals across the lifespan. We propose a focused integration of geography into person-centered practice: a clinical geography dedicated to working directly with people to promote optimal physical and mental health outcomes and wellbeing. Our proposal integrates spatial modifications to facilitate access and utility, behavioral interventions to maximize effectiveness in using space, and therapeutic engagement to nurture a deeper sense of ‘being in place’ that enhances wellbeing and quality of life. This focus is timely given societal instability and precariousness resulting from incongruous …

An Inactivated Bacterium (Paraprobiotic) Expressing Bacillus Thuringiensis Cry5b As A Therapeutic For Ascaris And Parascaris Spp. Infections In Large Animals, Joseph F. Urban, Martin K. Nielsen, David Gazzola, Yue Xie, Ethiopia Beshah, Yan Hu, Hanchen Li, Florentina Rus, Kelly Flanagan, Austin Draper, Sridhar Vakalapudi, Robert W. Li, Gary R. Ostroff, Raffi V. Aroian

Maxwell H. Gluck Equine Research Center Faculty Publications

Ascaris and Parascaris are important parasites in the family Ascarididae, large, ubiquitous intestinal-dwelling nematodes infecting all classes of vertebrates. Parasitic nematode drug resistance in veterinary medicine and drug recalcitrance in human medicine are increasing worldwide, with few if any new therapeutic classes on the horizon. Some of these parasites are zoonotic, e.g., Ascaris is passed from humans to pigs and vice versa. The development of new therapies against this family of parasites would have major implications for both human and livestock health. Here we tested the therapeutic ability of a paraprobiotic or dead probiotic that expresses the Bacillus …