Digital Commons Network^™

Grazing Land Contributions To Carbon Sequestration, Ronald F. Follett, G. E. Schuman

IGC Proceedings (1977-2023)

Key points

1. Grazing management can be used to increase soil organic carbon sequestration.

2. Grazing land soils contain large amounts of carbon with depth, and can store it for centuries.

3. Policies to encourage terrestrial carbon sequestration through conservation and good management of grazing lands are critical for many countries and the world.

Grassland Productivity And Water Quality: A 21St Century Issue, David M. Nash, P. M. Haygarth

IGC Proceedings (1977-2023)

Key points

1. Irrigation and other changes to the hydrological cycle can increase soil and water salinity.

2. Primary salinisation is a natural process that affects much of Europe, Asia, Africa, the Americas and Australia. Secondary salinisation is caused by human activities such as irrigation and land clearing that mobilise salt stored in the soil.

3. The critical water contaminants exported from grasslands are nitrogen, phosphorus, potential pathogens and sediment.

4. The mechanisms responsible for diffuse pollution from grasslands and mitigation strategies are most effectively investigated using a ‘source-mobilisation-transport’ framework.

5. There is a lack of coherent interaction across discipline …

Water Resources, Agriculture And Pasture: Implications Of Growing Demand And Increasing Scarcity, M. W. Rosegrant, R. A. Valmonte-Santos, S. A. Cline, C. Ringler, W. Li

IGC Proceedings (1977-2023)

Key points

1. Water availability for irrigation is threatened in many regions by rapidly increasing demand for nonagricultural water uses in industry, households, and the environment. The scarcity of irrigation water will not only impact crop production, but also meat production, as much of the pasture used to feed livestock is irrigated.

2. Grassland is caught between two countervailing forces: a requirement for increasing meat demand that boosts the need for additional pasture to support livestock production, and rapidly increasing water scarcity that makes pasture irrigation uneconomical.

3. The most effective means of dealing with water scarcity is likely to …

Soil Microbial Community: Understanding The Belowground Network For Sustainable Grassland Management, Y. G. Zhu, W. D. Kong, B. D. Chen, Z. B. Nan, P. Christie

IGC Proceedings (1977-2023)

Key points

1. In addition to the use of conventional methodologies in soil microbial research, molecular techniques are now being applied to gain insights into the soil microbial community;

2. Plant diversity can exert impacts on soil microbial diversity (through root activities and plant litter etc.), but may in itself be significantly altered by soil properties;

3. Soil microbial diversity largely determines the stability of soil ecosystems under biotic and abiotic perturbations.

4. Management of soil microbial diversity can only be achieved through better understanding their structures and functions.

Gingival Transcriptome Of Innate Antimicrobial Factors And The Oral Microbiome With Aging And Periodontitis, Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Linh Nguyen, Octavio A. Gonzalez

Center for Oral Health Research Faculty Publications

The epithelial barrier at mucosal sites comprises an important mechanical protective feature of innate immunity, and is intimately involved in communicating signals of infection/tissue damage to inflammatory and immune cells in these local environments. A wide array of antimicrobial factors (AMF) exist at mucosal sites and in secretions that contribute to this innate immunity. A non-human primate model of ligature-induced periodontitis was used to explore characteristics of the antimicrobial factor transcriptome (n = 114 genes) of gingival biopsies in health, initiation and progression of periodontal lesions, and in samples with clinical resolution. Age effects and relationship of AMF to …

Evolution Of Integrated Crop-Livestock Production Systems, Martin H. Entz, William D. Bellotti, J. M. Powell, S. V. Angadi, W. Chen, K. H. Ominski, B. Boelt

IGC Proceedings (1977-2023)

Key points

1. Many factors contribute to changes in the crop-livestock systems, but no logical end-point in the evolution process exists.

2. While benefits of integrated crop-livestock systems over specialised crop and livestock systems are well documented, there has been a move to specialised crop and livestock production.

3. Sustainability issues (manure nutrient concentration, soil quality maintenance, salinity, herbicide resistance, economic instability) have created a renewed interest in integrated crop-livestock systems.

4. Farmer adaptability is as an important link in the evolution between ‘states of integration’.

Grasslands For Production And The Environment, David R. Kemp, David L. Michalk

IGC Proceedings (1977-2023)

Key points

1. To manage grasslands for production and enhanced environmental values requires a redefinition of the frameworks within which management decisions are made, and a tailoring of practices to suit the ways that farmers operate.

2. Improving the perenniality and permanence of grasslands usually leads to better environmental and production outcomes.

3. There is a case for a more conservative approach to utilising grasslands in order to sustain the functioning of local ecosystems and to improve water quality, nutrient and energy cycling and biodiversity.

4. A landscape rather than paddock focus is more appropriate for meeting current grassland management …

Strategies To Mitigate Seasonality Of Production In Grassland-Based Systems, Claudio Porqueddu, S. Maltoni, John G. Mcivor

IGC Proceedings (1977-2023)

Key points

1. Fertilisation use and manipulation can cost-effectively alter species composition, increase seasonal herbage production and improve herbage quality.

2. Choice of suitable grassland species, varieties and mixtures offers opportunity to mitigate limitations of seasonal grassland production.

3. Special purpose fodder crops, cereals, shrubs and trees offer alternative or supplementary feed sources.

4. Manipulation of stocking rates, grazing systems, transhumance and pasture management at various times of the season are significant advantageous options.

5. Integration of different strategies is essential to mitigate seasonality in systems of animal production that must be inherently more sustainable over a longer time frame.

Grass And Forage Plant Improvement In The Tropics And Sub-Tropics, Liana Jank, Cacilda B. Do Valle, Rosangela M. S. Resende

IGC Proceedings (1977-2023)

Key points

1. The majority of tropical and subtropical forage grass genera and/or species have not yet been collected, or need further collection to be representative of their natural distribution.

2. New biotechnological techniques will only result in the release of superior forage cultivars if supported by strong breeding programs.

3. More funding and investment in the formation of strong public research teams in forage conservation and improvement are needed to guarantee the sustainability of tropical and subtropical pasture-based livestock systems in the future.

4. The creation of a permanent international working group on tropical and subtropical forages is essential …

Grass And Forage Improvement: Temperate Forages, Chris J. Pollock, M. T. Abberton, M. O. Humphreys

IGC Proceedings (1977-2023)

Key points

1. Plant breeding has contributed significantly to the development of effective grassland production systems.

2. New technologies offer enhanced precision in breeding and access to wider genetic variation.

3. The requirement for more sustainable production systems will require genetic improvements in complex traits where the use of new technology will be vital.

Improving The Quality Of Products From Grassland, Nigel D. Scollan, R. J. Dewhurst, A. P. Moloney, J. J. Murphy

IGC Proceedings (1977-2023)

Key points

1. Consumers are increasingly aware of the links between diet and health, and place increasing emphasis on nutritional quality as a component of product quality.

2. Meat and milk products are rich sources of nutrients such as omega-3 (n-3) fatty acids and conjugated linoleic acid, which offer health benefits to consumers.

3. Green plants are the primary source of n-3 fatty acids in the food chain.

4. Grassland production systems have the potential to enhance the content of beneficial fatty acids, improve stability (from higher antioxidant content) and alter sensory attributes of meat and milk.

5. Grassland offers …

Rising Demand For Meat And Milk In Developing Countries: Implications For Grasslands-Based Livestock Production, C. L. Delgado

IGC Proceedings (1977-2023)

Key points

1. Meat and milk consumption in developing countries has grown three times as fast as in developed countries over the past 30 years.

2. By 2020, developing countries will consume 72 million metric tons (mmt) more meat and 152 mmt more milk compared to 2002/3, dwarfing developed-country increases of 9 mmt for meat and 18 mmt for milk.

3. Ruminant livestock will account for 27% of the increase in global meat consumption between 2003 and 2020, up from 23% over the previous two decades.

4. The inflation-adjusted prices of livestock and feed grains are expected to fall only …

Region-Based Analysis Of Rare Genomic Variants In Whole-Genome Sequencing Datasets Reveal Two Novel Alzheimer’S Disease-Associated Genes: Dtnb And Dlg2, Dmitry Prokopenko, Sanghan Lee, Julian Hecker, Kristina Mullin, Sarah Morgan, Yuriko Katsumata, Michael W. Weiner, David W. Fardo, Nan Laird, Lars Bertram, Winston Hide, Cristoph Lange, Rudolph E. Tanzi

Sanders-Brown Center on Aging Faculty Publications

Alzheimer’s disease (AD) is a genetically complex disease for which nearly 40 loci have now been identified via genome-wide association studies (GWAS). We attempted to identify groups of rare variants (alternate allele frequency <0.01) associated with AD in a region-based, whole-genome sequencing (WGS) association study (rvGWAS) of two independent AD family datasets (NIMH/NIA; 2247 individuals; 605 families). Employing a sliding window approach across the genome, we identified several regions that achieved association p values <10⁻⁶, using the burden test or the SKAT statistic. The genomic region around the dystobrevin beta (DTNB) gene was identified with the burden and SKAT test and replicated in case/control samples from the ADSP study reaching genome-wide significance after meta-analysis (p_meta= 4.74 × 10⁻⁸ ). SKAT analysis also revealed region-based association around the Discs large homolog 2 (DLG2) …

Single Center Retrospective Review Of Post-Laparotomy Ct Abdomen And Pelvis Findings And Trends, Dylan C. Steffey, Emad A. Chishti, Maximo J. Acevedo, Luis F. Acosta, James T. Lee

Radiology Faculty Publications

Purpose: To identify common findings visualized on CT following damage control laparotomy, including post-surgical changes and additional injuries, and to determine change in frequency of post-laparotomy CT at our institution over time.

Methods: Single institution, IRB-Exempt, retrospective review of the University of Kentucky trauma registry from 1/2006 to 2/2019 for all trauma patients undergoing exploratory laparotomy initially and subsequently undergoing CT of the abdomen and pelvis within 24 hours. Operative findings from surgical operation notes and findings reported on post-laparotomy CT were recorded, including vascular and solid organ injuries, operative changes, free intraperitoneal fluid/air, and retroperitoneal findings. Next steps in …

Central Vs. Peripheral Vision During A Singe-Leg Drop Jump: Implications Of Dynamics And Patellofemoral Joint Stress, Junyoung Ko, Kyeongtak Song, Hoon Kim, Sae Yong Lee, Jihong Park

Athletic Training and Clinical Nutrition Faculty Publications

Landing on a single-leg without receiving direct visual information (e.g., not looking at the ground) may increase the risk of injury. We examined whether visual focus contributed to the changing lower-extremity dynamics and patellofemoral joint stress during a single-leg drop jump task. Twenty healthy volunteers visited the laboratory for three separate sessions. During each session, participants randomly performed either of two types of a single-leg drop jump task from a 30 cm high wooden box. Subsequently, participants looked at the landing spot (central vision condition) or kept their heads up (peripheral vision condition) when performing the task. Sagittal and frontal …

Preliminary Research On A Covid-19 Test Strategy To Guide Quarantine Interval In University Students, Jill M. Kolesar, Tyler Gayheart, Lance Poston, Eric Monday, Derek Forster, Elizabeth Belcher, Rani Jaiswal, J. Kirsten Turner, Donna K. Arnett, Eric B. Durbin, Joseph Monroe, Frank Romanelli, Susanne M. Arnold, C. Darrell Jennings, Heidi Weiss, Robert Dipaola

Pharmacy Practice and Science Faculty Publications

Following COVID-19 exposure, the Centers for Disease Control (CDC) recommends a 10–14-day quarantine for asymptomatic individuals and more recently a 7-day quarantine with a negative PCR test. A university-based prospective cohort study to determine if early polymerase chain reaction (PCR) negativity predicts day 14 negativity was performed. A total of 741 asymptomatic students in quarantine was screened and 101 enrolled. Nasopharyngeal swabs were tested on days 3 or 4, 5, 7, 10, and 14, and the proportion of concordant negative results for each day versus day 14 with a two-sided 95% exact binomial confidence interval was determined. Rates of concordant …

A Measure Of Srs/Srt Plan Quality: Quantitative Limits For Intermediate Dose Spill (R50%) In Linac-Based Delivery, Dharmin D. Desai, Ivan L. Cordrey, Ellis L. Johnson

Radiation Medicine Faculty Publications

Stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT) of multiple cranial targets using a single isocenter on conventional C-arm linear accelerators are rapidly developing clinical techniques. However, no universal guidelines for acceptable intermediate dose spill limits are currently available or widely accepted. In this work, we propose an intermediate dose spill guidance range for cranial SRS/SRT delivered on C-arm linacs with MLC collimation for single PTV plans and single isocenter multiple target plans with PTV volumes in the range 0.02–57.9 cm³. We quantify intermediate dose spill with the R50% metric (R50% = volume of 50% of prescription isodose cloud …

Combined Transhepatic And Transjugular Approach For Mechanical Thrombectomy Of Massive Tips Thrombosis, Jack B. Newcomer, Emad A. Chishti, Driss Raissi

Radiology Faculty Publications

Transjugular intrahepatic portosystemic shunt (TIPS) is a well-validated decompressive therapy option to manage ascites and variceal bleeding secondary to portal hypertension. Complications following TIPS procedures include hepatic encephalopathy, liver failure, and TIPS dysfunction. TIPS dysfunction is due to occlusion or stenosis of the TIPS shunt and can be caused by acute or chronic thrombosis. TIPS thrombosis is often treated with mechanical thrombectomy or catheter-directed thrombolytic therapy. Most cases of in-stent occlusion can be treated via a transjugular approach with recanalization or placement of additional stents. We present a case of a 72-year-old female who presented with worsening ascites 17 months …

Forage News [2022-03], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

No abstract provided.

Music Therapy In Us Corrections: Philosophy, Practice, And Protocols Of Music Therapists Working With Incarcerated People In The Us, Lorna E. Segall, Olivia S. Yinger

Music Faculty Publications

Although the United States has the highest incarceration rate in the world and music therapy has existed in U.S. correctional facilities for almost a century, little is known about music therapists who provide services to people who are incarcerated. Exploration in this area is important as it could help inform clinical practice, music therapy curriculum, and potentially influence policy in the treatment of inmates. This study explores the philosophy, practices, and protocols of music therapists working in the U.S. corrections system. Board-certified music therapists ( N = 542) completed an online survey in which they indicated their reasons for working …

Electric Vehicles: Analysis Of Revenue Issues And Charging Station Implementation Plans, Chris Van Dyke, Bryan Gibson, Ryan Griffith, Andrew Martin, Jeeyen Koo, Doug Kreis

Kentucky Transportation Center Research Report

No abstract provided.

Apolipoprotein E Proteinopathy Is A Major Dementia-Associated Pathologic Biomarker In Individuals With Or Without The Apoe Epsilon 4 Allele, Jozsef Gal, Yuriko Katsumata, Haining Zhu, Sukanya Srinivasan, Jing Chen, Lance Allen Johnson, Wang-Xia Wang, Lesley Renee Golden, Donna M. Wilcock, Gregory A. Jicha, Matthew D. Cykowski, Peter Tobias Nelson

Spinal Cord and Brain Injury Research Center Faculty Publications

The amygdala is vulnerable to multiple or “mixed” mis-aggregated proteins associated with neurodegenerative conditions that can manifest clinically with amnestic dementia; the amygdala region is often affected even at earliest disease stages. With the original intent of identifying novel dementiaassociated proteins, the detergent-insoluble proteome was characterized from the amygdalae of 40 participants from the University of Kentucky Alzheimer’s Disease Center autopsy cohort. These individuals encompassed a spectrum of clinical conditions (cognitively normal to severe amnestic dementia). Polypeptides from the detergent-insoluble fraction were interrogated using liquid chromatography-electrospray ionization-tandem mass spectrometry. As anticipated, portions of peptides previously associated with neurologic diseases were …

Autologous Haematopoietic Stem Cell Transplantation And Systemic Sclerosis: Focus On Interstitial Lung Disease, Gianluca Bagnato, Antonio Giovanni Versace, Daniela La Rosa, Alberta De Gaetano, Egidio Imbalzano, Marianna Chiappalone, Carmelo Ioppolo, William Neal Roberts, Alessandra Bitto, Natasha Irrera, Alessandro Allegra, Giovanni Pioggia, Sebastiano Gangemi

Internal Medicine Faculty Publications

Autologous hematopoietic stem cells transplantation (AHSCT) has been employed as treatment for severe systemic sclerosis (SSc) with high risk of organ failure. In the last 25 years overall survival and treatment-related mortality have improved, in accordance with a better patient selection and mobilization and conditioning protocols. This review analyzes the evidence from the last 5 years for AHSCT-treated SSc patients, considering in particular the outcomes related to interstitial lung disease. There are increasing data supporting the use of AHSCT in selected patients with rapidly progressive SSc. However, some unmet needs remain, such as an accurate patient selection, pre-transplantation analysis to …

Body Condition Score Change Throughout Lactation Utilizing An Automated Bcs System: A Descriptive Study, Carissa M. Truman, Magnus R. Campler, Joao H. C. Costa

Animal and Food Sciences Faculty Publications

Body condition scoring (BCS) is a traditional visual technique often using a five-point scale to non-invasively assess fat reserves in cattle. However, recent studies have highlighted the potential in automating body condition scoring using imaging technology. Therefore, the objective was to implement a commercially available automated body condition scoring (ABCS) camera system to collect data for developing a predictive equation of body condition dynamics throughout the lactation period. Holstein cows (n = 2343, parity = 2.1 ± 1.1, calving BCS = 3.42 ± 0.24), up to 300 days in milk (DIM), were scored daily using two ABCS cameras mounted …

Smallholder Dairy Farmers In The Peruvian Andes Fulfilling The Role Of Extension Agents, C. S. Pinares-Patino, J. Manhire, R. Garcia Ticllacuri, J. L. Bernal Madrid, V. M. Velez Marroquin

IGC Proceedings (1977-2023)

Dairy farming in the Peruvian Andes is mostly undertaken by smallholder farmers (4-6 cows/family) and of relatively recent development. In fact, over the last 2 decades dairy farming at high altitudes (3,500‒4200 masl) has grown rapidly, replacing the camelids and sheep farming that once predominated. Dairying growth has been catalysed by subsides from state and private organizations. It promotes high input systems based on feedlot technology. Compared to sheep and camelids farming, dairying at the Andes does not have yet an inherent local/indigenous knowledge associated to it. High altitude Andean ecosystems pose many constraints for dairy farming (hypoxia and high …

Acetylsalicylic Acid Suppresses Alcoholism-Induced Cognitive Impairment Associated With Atorvastatin Intake By Targeting Cerebral Mirna155 And Nlrp3: In Vivo, And In Silico Study, Doaa I. Mohamed, Dalia Alaa El-Din Aly El-Waseef, Enas S. Nabih, Omnyah A. El-Kharashi, Hanaa F. Abd El-Kareem, Hebatallah H. Abo Nahas, Basel A. Abdel-Wahab, Yosra A. Helmy, Samar Zuhair Alshawwa, Essa M. Saied

Veterinary Science Faculty Publications

Alcoholism is one of the most common diseases that can lead to the development of several chronic diseases including steatosis, and cognitive dysfunction. Statins are lipid-lowering drugs that are commonly prescribed for patients with fatty liver diseases; however, the exact effect of statins on cognitive function is still not fully understood. In the present study, we have investigated the molecular and microscopic basis of cognitive impairment induced by alcohol and/or Atorvastatin (ATOR) administration to male Wistar albino rats and explored the possible protective effect of acetylsalicylic acid (ASA). The biochemical analysis indicated that either alcohol or ATOR or together in …

Pastoralist Conservation: Local Ecological Knowledge And Collective Action For Grassland Conservation In Sierra De Segura (Spain), P. Sanosa-Cols, F. Ravera, F. Dominguez, M. Ventura

IGC Proceedings (1977-2023)

Even if Pastoralism is not practised anymore by a majority of families in the Sierra de Segura (south-eastern Andalusia, Spain), it is still considered a paradigmatic way of life and management of its highlands and a key cultural heritage deeply rooted in local identity. In this article we explore two pastoral communities of this region, Santiago and Pontones, with their body of situated knowledge of the territory and natural resources, which helps pastoralists to organize their livelihoods, while requiring collective organization to manage access to grasslands. Through an ethnographic research based on participant observation and in-depth interviews, we explore the …

Perceptions Of Rangeland Degradation In The Peruvian Altiplano Dry Puna And Implications, C. Turin, J. Gilles

IGC Proceedings (1977-2023)

The Peruvian altiplano’s dry puna is the main feed source for specialized alpaca pastoralist systems. Experts argue that rangelands are severely degraded and have formulated policies and programs to address this. However, these programs have had little success. This paper presents a qualitative case study of the perceptions of rangeland degradation held in three Aymara communities, by range scientists of academia, personnel of NGOs operating in the region and by government officers. We found that each of these groups had distinct views of the level and causes of degradation in the region. Differences in perceptions undermined cooperation and trust between …

Endangered Sustainable Innovation: Indigenous Milk Hygiene And Preservation Techniques By Maasai Too Valuable To Lose, J. Y. Laffa, C. R. Mcculloch, D. Schoder

IGC Proceedings (1977-2023)

The indigenous Parakuyo Maasai communities of Tanzania are traditional pastoralists who depend on fresh cow’s milk as a staple food. However, the arid climate and a lack of clean water challenge milk production and conventional milk hygiene practices.

By conducting informational interviews in eight Parakuyo Maasai regions and 13 districts of Tanzania we sought to identify the key indigenous plants preferred and establish their traditional manner of use. A semi-structured questionnaire was designed to: (i) determine the plants used, (ii) the parts used, (iii) methods of preparation and utensil smoking, (iv) therapeutic applications and associated health benefits of these plants, …

Could Cheese Be The Missing, Hard, Stable Currency To Fortify Self-Sufficiency Of Pastoralist Communities?, D. Schoder, J. Y. Laffa

IGC Proceedings (1977-2023)

Traditional pastoral existence in Africa has always necessitated close, sustainable interaction with a harsh natural environment. Pastoralists, such as the indigenous Parakuyo Maasai of Tanzania traditionally depend on fresh cow’s milk as a staple. They are among the few African ethnic groups that still live as small, socially intact associations close to nature. Unfortunately, fresh milk is difficult to store and inevitably, times of plenty fluctuate with the times of hunger that threaten cultural retreat. Milk storage is particularly challenging in an arid climate without refrigeration and at such times, survival takes precedence over prosperity. We describe an ongoing pilot …