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Plasma Native And Peptidase-Derivable Met-Enkephalin Responses To Restraint Stress In Rats. Adaptation To Repeated Restraint, K. Pierzchala, G. R. Van Loon

Internal Medicine Faculty Publications

Met-enkephalin and related proenkephalin A-derived peptides circulate in plasma at picomolar concentration as free, native pentapeptide and at nanomolar concentration in cryptic forms. We have optimized conditions for measurement of immunoreactive Met-enkephalin in plasma and for generation by trypsin and carboxypeptidase B of much greater amounts of total peptidase-derivable Met-enkephalin in plasma of rats, dogs, and humans. Free Met-enkephalin (11 pM) is constituted by native pentapeptide and its sulfoxide. Characterization of plasma total Met-enkephalin derived by peptidic hydrolysis revealed a small amount (38 pM) of Met-enkephalin associated with peptides of molecular mass less than 30,000 D, and probably derived from …

Alfalfa Producers: Do You Really Know How Good Your Alfalfa Is? Forage Analysis: Importance And Interpretation, Jimmy C. Henning

Kentucky Alfalfa and Stored Forage Conference

Forages make up over 75% of the diet of all cattle and are the basis of cow-calf industry in the midwest. However, a recent survey of over 1000 livestock producers in Missouri revealed that only 5.6 % had ever had their hay tested. They gave several reasons for why they had not tested hay (Table 1). By a large margin, the greatest reason for not testing was that they did not see a need. This fact highlights the purpose of this paper and presentation at the 10th Annual Kentucky Alfalfa Conference. This paper will explain the terms used in …

Oral Drug Retaining Device, Jesse B. Douglas Jr.

Oral Health Science Faculty Patents

An oral drug retaining device includes a receptacle for receiving and holding a polymer matrix impregnated with a pharmacologic agent. The receptacle is formed by a cooperating basket and frame. The basket and frame include a hinge at one side and a latch pin at the opposite side to allow the receptacle to be selectively opened and closed to replace the polymer matrix as desired. Cooperating male and female connectors are provided to allow the receptacle to be releasably mounted to a tooth of a patient. One of these connectors is adapted for mounting to a tooth while the other …

Automobile Accident Litigation In Kentucky, Office Of Continuing Legal Education At The University Of Kentucky College Of Law, Robert D. Monfort

Continuing Legal Education Materials

A practitioner's handbook that walks attorneys through the litigation processes arising from automobile accidents and related issues.

Disease Management In The Home Lawn, Paul C. Vincelli, A. J. Powell Jr.

Agriculture and Natural Resources Publications

Numerous infectious diseases can occur on lawns in Kentucky. Unless diagnosed and managed, these diseases can sometimes cause extensive damage. A sound disease management program benefits your lawn in two ways:

• reduces the severity of lawn diseases
• improves the lawn's recovery should a disease outbreak occur.

This publication describes lawn management practices that can help control diseases of turfgrasses commonly used in home lawns -- Kentucky bluegrass, tall fescue, and perennial ryegrass. You can control diseases of turfgrasses most effectively by using as many of the following lawn management practices as feasible.

The first step in improving your lawn is …

Right To Farm, J. L. Taraba, R. M. Williams

Agricultural Engineering Extension Updates

Landowners in general have the right to use their property in any manner they might find useful or enjoyable except when that use infringes on the right of their neighbor or community to use their property. Conflicting interests of neighbors have been the subject of numerous disagreements resulting in one or the other loosing his right to use his property as he wishes. The circumstances surrounding each conflict usually determines the outcome, and farmers should be aware that their right to farm may be at the mercy of courts who have sometimes been sympathetic to grievances of their more urban …

Home Water Disinfection Methods, Joseph L. Taraba, Thomas W. Ilvento, Linda M. Heaton

Agricultural Engineering Extension Updates

The source of bacteria in your water supply can come from the water source itself, the contamination of the well and/or piping system during maintenance or construction or improper well construction. There are four disinfection methods available for the private water system:

• Chlorination (simple chlorination, super chlorination and shock chlorination)
• Ultraviolet (UV) light
• Ozonation

Do You Need A Water Treatment Product?: What You Need To Know And Ask Before Buying, Joseph L. Taraba, Linda M. Heaton, Thomas W. Ilvento

Agricultural Engineering Extension Updates

A homeowner may have obvious problems with the drinking water system; such as, staining of porcelain sinks, stained clothes after washing, cloudy water, foul/funny tasting or smelling water or corrosion of faucets or plumbing. The homeowners may be very concerned about their water because of recent publicity, advertisements or door-to-door sales which raised issues about the quality of the drinking water from a private or public water supply. The homeowners may be concerned about the water supply after a recent educational program that was attended or presented in the local media outlets. How does that homeowner determine if a water …

Protection Of Private Groundwater Drinking Supplies, Joseph L. Taraba, Jim Dinger, James Webb

Agricultural Engineering Extension Updates

There are three general objectives that this slide presentation concentrates on; First of all, we want to acquaint you with the hydrologic cycle. If one understands this cycle; then, an appreciation for what activities might contaminate our water supplies can be obtained. Secondly, we want to review some of the land use practices that may result in water resource contamination. Thirdly, we want to review well construction and maintenance practices that may result in contamination of an individuals source of drinking water. That brings us to the major goal of this entire program. This major goal is to get each …

Practice And Procedure Before Racing Commissions, Jewel N. Klein, Ray H. Garrison

Kentucky Law Journal

No abstract provided.

Bulletin Of The University Of Kentucky College Of Law – 1990-1992, University Of Kentucky College Of Law

College of Law Bulletins

The Bulletin of the University of Kentucky College of Law served numerous purposes, including: a course catalog, a roster of students, a roster of professors, an academic calendar, a listing of special events and lectures, academic policies, admission requirements, graduation requirements, and various other policies and benefits governing student life.

Macrophages But Not B Cells From Aged Mice Are Defective In Stimulating Autoreactive T Cells In Vitro, Aruna Seth, Mitzi Nagarkatti, Prakash S. Nagarkatti, Subbarao Bondada, Venkatachalam Udhayakumar

Microbiology, Immunology, and Molecular Genetics Faculty Publications

In the present study the effect of aging on the capacity of Ia⁺ cells to stimulate autoreactive T cells in the syngeneic mixed lymphocyte reaction (SMLR) was investigated. Using young CD4⁺ T cells as responders, it was observed that unseparated whole spleen cells from aged mice had normal stimulatory activity comparable to that of young spleen cells. Interestingly, however, when purified splenic adherant cells (SAC) enriched for macrophages or splenic B cells were used as stimulators, aged SAC but not aged B cells were found to be defective in stimulating autoreactive T cells. This defect in aged SAC …

Unavoidably Unsafe Products And Strict Products Liability: What Liability Rule Should Be Applied To The Sellers Of Pharmaceutical Products?, Richard C. Ausness

Kentucky Law Journal

No abstract provided.

Prenatal Injuries From Passive Tobacco Smoke: Establishing A Cause Of Action For Negligence, Julie E. Lippert

Kentucky Law Journal

No abstract provided.

Indices To Volume 78, Kentucky Law Journal

Kentucky Law Journal

No abstract provided.

State Prosecutions For Safety-Related Crimes In The Workplace: Can D.A.'S Succeed Where Osha Failed?, S. Douglas Jones

Kentucky Law Journal

No abstract provided.

The Kentucky No Action Statute: Down For The Count?, Anne E. Gorham

Kentucky Law Journal

No abstract provided.

The Supreme Court In Transition: Assessing The Legitimacy Of The- Leading Legal Institution, Christopher E. Smith

Kentucky Law Journal

No abstract provided.

Compensation For Smoking-Related Injuries: An Alternative To Strict Liability In Tort, Richard C. Ausness

Law Faculty Scholarly Articles

The Surgeon General has described cigarette smoking as the "single most important preventable environmental factor contributing to illness, disability and death in the United States." Each year, smoking-related diseases claim more than 350,000 lives. Smoking-related illnesses also impose a huge economic burden on society. Estimates of health care costs range from $12 billion to $22 billion per year, and productivity losses due to illness and death are even greater.

Arguably, cigarette companies and their customers ought to bear the health costs of smoking. At the present time, however, the tobacco industry has largely escaped responsibility for these costs. Instead, smoking-related …

Phenotypic And Functional Properties Of B Lymphocytes From Aged Mice, Subbarao Bondada, Joan Morris, Richard J. Kryscio

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Phenotypic and functional properties of B lymphocytes from individual young and old mice of different inbred strains were studied. B lymphocyte subpopulation defined by the ratios of the densities of cell surface IgM and IgD were found to be altered with age. However, such alterations in B cell subsets were found only in 30-40% of the old mice. B cell mitogenic responses to anti-μ and anti-Lyb2 antibodies were decreased in a majority of DBA/2 mice. Proliferative responses to LPS and antiμ were reduced only in a minority of CBA/Ca mice but there was a very good correlation in the responsiveness …

Novel Method Of Administering Aspirin And Dosage Forms Containing Same, Anwar A. Hussain, Lewis W. Dittert, Thomas S. Foster

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering aspirin to achieve improved delivery thereof. The invention further relates to novel dosage forms of neutralized aspirin adapted for nasal administration, such as solutions, suspensions, gels and ointments. These dosage forms find utility in the treatment of conditions known to respond to the administration of aspirin, particularly in the treatment of migraine and in the mitigation of cardiovascular damage resulting from heart attack.

Integrated Truck Monitoring System, Jerry G. Pigman, John A. Deacon

Kentucky Transportation Center Research Report

The primary objectives of the study are as follows: 1) Develop functional specifications for an integrated truck monitoring system for use in Kentucky, 2) Determine the extent to which KYU numbers (unique identification for large trucks operating in Kentucky) are being displayed as required, 3) Examine the impact of the KYU numbering system on motor carrier operations, and 4) Determine the magnitude of the problems related to trucks using bypass routes to avoid inspection stations.

Accomplishments documented in this interim report include the following: 1) Field studies were conducted to determine the frequency of trucks bypassing inspection stations and compliance …

Qualitative Metabolism Assessment Using High Performance Thin Layer Chromatography, Shih-Ling Chang

Veterinary Science Faculty Patents

A method for the qualitative assessment of oxidative drug metabolism deficiencies, preferably for the qualitative assessment of dextromethorphan metabolism, in a subject comprises analyzing a sample fluid from the subject, for example urine, which contains metabolites of a probe drug using high performance thin layer chromatography.

Law Enforcement And Engineering Incident Management—A Necessary Partnership: Incident Management, Jerry L. Lentz, James H. (Mike) Molloy, Sam W. Lester, Pat Dugger, William R. Monhollon, Robert L. Freeman, Mike Duncan

Kentucky's Annual Forum on Transportation

No abstract provided.

Design And Construction Of Safe Roads And Streets: Opening Remarks, O. Gilbert Newman

Kentucky's Annual Forum on Transportation

No abstract provided.

Keynote Address [1989], B. J. Campbell

Kentucky's Annual Forum on Transportation

No abstract provided.

Opening Remarks [1989], Calvin G. Grayson

Kentucky's Annual Forum on Transportation

No abstract provided.

Letter To Committee Members Concerning Letters To Library School Deans, October 2, 1989, Hazel Johnson

Newsletter and Public Relations Committee

A letter from Hazel Johnson to members of the Publicity and Public Relations Committee concerning the second letter to Library School Deans. The letter also includes a draft of the second dean letter, a committee activities timetable, a SEAALL Annual Meeting program, and a Long, Aldridge & Norman firm brochure.

Some Muniments Of Bell Court, Lexington, James D. Birchfield

The Kentucky Review

No abstract provided.

Method And Composition For Safely Delaying Parturition And Synchronizing Farrowing In Swine, Lee A. Edgerton, Bruce T. Eckerle

Animal and Food Sciences Faculty Patents

A method and composition are provided for extending the gestation period of a sow so as to increase the live birth and survival rates of a swine litter without adversely affecting the sow. The method includes the step of administering an effective dosage of estrogen to the sow 21/2-7 days prior to the end of the expected gestation period for the sow. The composition administered includes from 0.5-10 mg of an estrogen selected from a group consisting of estradiol benzoate, estradiol valerate, estrone, estradiol 17β and effective mixtures thereof. The composition is adapted for administration parenterally by including a carrier …