Digital Commons Network^™

Developing The Next Generation Of Technological Aids To Effective Public Involvement In Public Transportation Planning & Design, C. Anneta Arno Anneta, Keiron Bailey, Ted H. Grossardt

Kentucky Transportation Center Faculty and Researcher Publications

Problem

Public involvement in the design of complex public infrastructure solutions, such as a new light rail line, including stops, stations and transit centers, and associated Transit- Oriented Developments (TOD), often relies on lengthy public meetings during which the complexities and subtleties of design preferences, their articulation and communication is overwhelming to both participants and design professionals. Such gatherings can produce more confusion than clarity for the public and design professional alike, especially when strong personalities highlight differences and discourage compromise and consensus. More effective methods of discerning, developing and evaluating the nature of the public’s different preferences and perspectives, …

Hdl-Associated Estradiol Stimulates Endothelial No Synthase And Vasodilation In An Sr-Bi–Dependent Manner, Ming Gong, Melinda E. Wilson, Thomas Kelly, Wen Su, James Dressman, Jeanie Kincer, Sergey V. Matveev, Ling Guo, Theresa Guerin, Xiang-An Li, Weifei Zhu, Annette M. Uittenbogaard, Eric J. Smart

Pediatrics Faculty Publications

Cardiovascular diseases remain the leading cause of death in the United States. Two factors associated with a decreased risk of developing cardiovascular disease are elevated HDL levels and sex — specifically, a decreased risk is found in premenopausal women. HDL and estrogen stimulate eNOS and the production of nitric oxide, which has numerous protective effects in the vascular system including vasodilation, antiadhesion, and anti-inflammatory effects. We tested the hypothesis that HDL binds to its receptor, scavenger receptor class B type I (SR-BI), and delivers estrogen to eNOS, thereby stimulating the enzyme. HDL isolated from women stimulated eNOS, whereas HDL isolated …

Addressing The Decline In Reproductive Performance Of Lactating Dairy Cows: A Researcher’S Perspective, William J. Silvia

Animal and Food Sciences Faculty Publications

No abstract provided.

Method For Enhancing Protective Cellular Responses To Genotoxic Stress In Skin, Elaine L. Jacobson, Myron Jacobson

Graduate Center for Nutritional Sciences Faculty Patents

The present invention is directed to methods of using pro-NAD agents capable of enhancing the dermal and epidermal skin cell NAD content. These pro-NAD agents may be administered topically, orally, or parenterally to enhance DNA repair and other protective responses to DNA damage. The invention further relates to pharmaceutical compositions comprising pro-NAD agents that effectively elevate intracellular NAD content. Finally, the invention relates to the method of using the pro-NAD agents to treat disorders such as sunburn and other skin deterioration that results from DNA damage in skin cells.

Beyond The State: The Return To Anarchy, Jeff Shantz

disClosure: A Journal of Social Theory

No abstract provided.

Separate Stories, Common Myth: Disclosure Interviews Martin E. Marty, Walter Bower, Jonathan Vincent

disClosure: A Journal of Social Theory

No abstract provided.

Seventeen Amino Acid Peptide (Peptide P) For Treating Ischemia And Reperfusion Injury, Peter R. Oeltgen, Mark S. Kindy

Molecular and Cellular Biochemistry Faculty Patents

Peptide P, having the amino acid sequence Tyr-D-Ala-Phe-Ala-Asp-Val-Ala-Ser-Thr-Ile-Gly-Asp-Phe-Phe-His-Ser-Ile-NH2, is useful to treat ischemia.

23rd Annual Conference On Legal Issues For Financial Institutions, Office Of Continuing Legal Education At The University Of Kentucky College Of Law

Continuing Legal Education Materials

Materials from the 23rd Annual Conference on Legal Issues for Financial Institutions held by UK/CLE in April of 2003.

What Gets Judges In Trouble, Richard H. Underwood

Law Faculty Scholarly Articles

I wrote this article to collect some cautionary material about “what gets judges in trouble.” I wanted something I could offer to our state judges, practitioners, and my legal ethics students. While I have never been a judge, and while I have never worked for a judicial conduct organization, I have been a law professor for almost twenty-five years and the chairman of a state bar association ethics committee for fourteen. I am not the kind of person who would refrain from holding forth just because I may not know what I am talking about.

When I started out, I …

A Solution To The Yahoo! Problem? The Ec E-Commerce Directive As A Model For International Cooperation On Internet Choice Of Law, Mark F. Kightlinger

Law Faculty Scholarly Articles

In May 2000, a French court decided that a French law banning the display of Nazi materials for sale applies to an auction website hosted by the California-based company Yahoo! Inc. The following year, at the request of Yahoo! Inc., a U.S. District Court declared that the French judgment was unenforceable in the United States because enforcing it would violate an important public policy-the First Amendment. These two cases have attracted considerable attention because they crystallize a difficult problem. The Internet is global. Every website potentially reaches every home on the planet. Thus, website content or activity that may be …

Two Laborers Die From A Scaffolding Fall Inside A Water Tank, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Falls

Two 20 year-old laborers died after falling approximately 25 feet from suspension scaffolding while preparing the inside of a municipal water tank for painting. Neither laborer was wearing fall personal protection equipment at the time of the fatal incident. The laborers were preparing the inside of a 200,000-gallon water tank for painting when one end of the scaffolding dropped after a support cable slipped. The job foreman arrived at the job site and entered the tank to check on the laborers. He found both laborers on the tank floor. Laborer 1 had respiratory vital signs but Laborer 2 did not. …

Hispanic Worker Dies Due To Trench Cave-In, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Other

On December 3, 2002, a 30-year old Hispanic laborer died when an unsupported 8-foot wall of a trench collapsed on him. Three laborers were working in an unsupported trench when one side caved in, burying one laborer (decedent) and partially burying another Hispanic worker. The third laborer managed to escape the trench unharmed. Two of the laborers were Hispanic, the third was a brother to the owner of the company digging the trench. The coroner pronounced the 30-year old laborer dead at the scene due to asphyxiation.

To prevent similar incidents from occurring, Kentucky Fatality Assessment and Control Evaluation personnel …

Freedom! Red Clover—A New Variety For Kentucky, Norman L. Taylor, Michael Collins

Agriculture and Natural Resources Publications

Freedom! is a new variety of red clover developed by the Kentucky Agricultural Experiment Station and released in 2001. It is a medium red clover variety adapted to the same general region as Kenland, i.e., Kentucky and the central clover region of the United States.

Freedom!—so named because of its freedom from pubescence (non-glandular hairs)—was developed to permit faster drying and to reduce dustiness of hay. It is especially recommended for hay because it is less dusty than other varieties. Less dustiness should result in improved air quality that may be associated with reduced health hazard for both humans and …

The Development Of Relationships Between Constituent Concentrations And Generic Hydrological Variables, Carmen T. Agouridis, Dwayne R. Edwards

Biosystems and Agricultural Engineering Faculty Publications

The collection and analysis of samples from storm events constitutes a large portion of the effort associated with water quality research. Estimating concentrations or loads from these events is often difficult. The equipment necessary to analyze the samples and the required laboratory resources are typically significant expenses incurred by the researcher. One potential method to reduce these costs is through the development of generic relationships between concentrations and easily measured variables such as dimensionless flow rate or time. The benefits recognized from such an effort include a reduction in the number of required samples, resulting in a reduction in cost. …

Glucuronidation Enzymes, Genes And Psychiatry, Jose De Leon

Psychiatry Faculty Publications

The phase I cytochrome P450 (CYP) isoenzymes have received substantial attention in the pharmacogenetic literature. Researchers are beginning to examine the role of the phase II UDP-glucuronosyltransferase (UGT) enzymes, which produce products that are more water-soluble, less toxic and more readily excreted than the parent compounds. Several reasons may have contributed to neglect of UGTs (compared to CYPs) including: (1) the overlapping activity of UGTs and lack of selective probes; (2) the complexity of the glucuronidation cycle; and (3) the difficulty in developing analytic methods to measure glucuronides. Current CYP knowledge is used as a model to predict advances in …

Maintenance Painting Of Various Bridge Projects During 2001-2002: Kentucky Highway Investigative Task 42, Rick Younce, Sudhir Palle, Theodore Hopwood Ii

Kentucky Transportation Center Research Report

The Kentucky Transportation Center (KTC) at the University of Kentucky has performed a series of research studies for the Kentucky Transportation Cabinet (KYTC) to monitor various experimental bridge painting projects and conduct investigative work focusing on new paint systems. The research study addressed in this report “Maintenance Painting of Various Bridge Projects During 2001-2002” Kentucky Highways Investigative Task No: 42 were intended to address experimental projects in fiscal years 2001 and 2002.

KTC and KYTC Project Design Team’s joint efforts in 2000 into early 2001 centered on the preparation of experimental bridge maintenance painting special notes, preliminary field testing/development of …

Alfalfa, The Queen Of Forage Crops — Reflections After Sixty Years Experience With The Crop, Warren C. Thompson

Kentucky Alfalfa and Stored Forage Conference

Yes, it is true I have been involved with alfalfa for 60 years and then some. Fact is I was fortunate enough to pick the World's best forage on which to base much of my career about the same time I fell in love with and married the best lady I ever knew. Betty has stuck with me through these crazy wonderful years. She was largely responsible for matters at home and raising the family. She managed our family and home while I was on the move trying to encourage maybe even coerce farmers in Kentucky and then over the …

Hiv Protease Inhibitors Promote Atherosclerotic Lesion Formation Independent Of Dyslipidemia By Increasing Cd36-Dependent Cholesteryl Ester Accumulation In Macrophages, James Dressman, Jeanie Kincer, Sergey V. Matveev, Ling Guo, Richard N. Greenberg, Theresa Guerin, David Meade, Xiang-An Li, Weifei Zhu, Annette M. Uittenbogaard, Melinda E. Wilson, Eric J. Smart

Physiology Faculty Publications

Protease inhibitors decrease the viral load in HIV patients, however the patients develop hypertriglyceridemia, hypercholesterolemia, and atherosclerosis. It has been assumed that protease inhibitor–dependent increases in atherosclerosis are secondary to the dyslipidemia. Incubation of THP-1 cells or human PBMCs with protease inhibitors caused upregulation of CD36 and the accumulation of cholesteryl esters. The use of CD36-blocking antibodies, a CD36 morpholino, and monocytes isolated from CD36 null mice demonstrated that protease inhibitor–induced increases in cholesteryl esters were dependent on CD36 upregulation. These data led to the hypothesis that protease inhibitors induce foam cell formation and consequently atherosclerosis by upregulating CD36 and …

Monoclonal Antibody 1a7 And Use For The Treatment Of Melanoma And Small Cell Carcinoma, Malaya Chatterjee, Kenneth A. Foon, Sunil K. Chatterjee

Microbiology, Immunology and Molecular Genetics Faculty Patents

The present invention relates to monoclonal antibody 1A7. This is an anti-idiotype produced by immunizing with an antibody specific for ganglioside GD2, and identifying a hybridoma secreting antibody with immunogenic potential in a multi-step screening process. Also disclosed are polynucleotide and polypeptide derivatives based on 1A7, including single chain variable region molecules and fusion proteins, and various pharmaceutical compositions. When administered to an individual, the 1A7 antibody overcomes immune tolerance and induces an immune response against GD2, which comprises a combination of anti-GD2 antibody and GD2-specific T cells. The invention further provides methods for treating a disease associated with altered …

Bridged Nicotine Compounds For Use In The Treatment Of Cns Pathologies, Peter A. Crooks, Linda P. Dwoskin, Rui Xu, Vladimir P. Grinevich

Pharmaceutical Sciences Faculty Patents

Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) having selective antagonist properties at α3β2-containing nicotinic receptor subtypes, and compositions containing these compounds. The compounds and compositions are used to treat central nervous system pathologies.

Lower Class Mobilization And State Welfare Policy In The Era Of Welfare Reform, James M. Avery, Mark Peffley

University of Kentucky Center for Poverty Research Discussion Paper Series

The 1990s played host to the most significant changes in the American welfare system in the last fifty years— in particular, states were granted much wider latitude in deciding who is eligible to receive welfare. Taking advantage of these changes, we examine the linkage between lower class turnout and state adoption of restrictive welfare eligibility requirements after the passage of the historic welfare reform legislation of 1996. We find that in states where lower class turnout was relatively high, lawmakers were much less likely to pass a range of “get tough” welfare rules. Our findings provide novel support for the …

Poverty And Macroeconomic Performance Across Space, Race, And Family Structure, Craig Gundersen, James P. Ziliak

University of Kentucky Center for Poverty Research Discussion Paper Series

Understanding the link between poverty and economic growth is of long-standing interest, but heretofore it has not received much attention within the context of the dramatic changes in recent business-cycle conditions and social policies. In this paper we use state-level panel data from the 1981–2000 waves of the Current Population Survey to examine the impacts of the macroeconomy and welfare reform on family poverty. We estimate models of before-tax and after-tax poverty rates and squared poverty gaps for all families, by family structure, and by race. Our results indicate that a strong macroeconomy at both the state and national levels …

The Impact Of Welfare Programs On Poverty Rates: Evidence From The American States, Richard Fording, William D. Berry

University of Kentucky Center for Poverty Research Discussion Paper Series

There is spirited debate between those who maintain that public assistance to the poor decreases poverty by raising their incomes (an income enhancement effect) and those who contend that welfare increases poverty by discouraging the poor from working (a work disincentive effect). Extant studies have been inconclusive because they have focused on the effect of welfare benefits on the poverty rate, but have not employed designs that allow researchers to sort out distinct income enhancement and work disincentive effects. We develop a model of poverty rates in the American states that permits estimation of these distinct effects ñ based on …

Obesity And The Development Of Complications Across The Life Span: Is There A Relationship Between Obesity And Poverty, Mildred D. Fennal

University of Kentucky Center for Poverty Research Discussion Paper Series

The purpose of this investigation was to examine the relationship between the development of obesity in children ages five to ten years, and poverty (the socio-economic status of the family). Because of the associated complications of obesity such as heart disease, stroke, diabetes and hypertension, this research aimed to determine if obesity, a precursor of these diseases, was related to poverty.

The rate of the development of hypertension and diabetes in children and young adults has been steadily increasing over the past ten years (Hines, Fishman, Green, 1999). Therefore, there is an urgent need for continued investigation exploring the multiple …

Kentucky Water Resources Research Institute Annual Technical Report Fy 2002, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY 2002 Annual Technical Report for Kentucky consolidates reporting requirements of the Section 104(b) base grant award in a single technical report that includes: 1) a synopsis of each research project supported during the period, 2) a list of related reports, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable achievements and awards during the year.

The Role Of Food Stamps In Consumption Stabilization, Craig Gundersen, James P. Ziliak

University of Kentucky Center for Poverty Research Discussion Paper Series

The Food Stamp Program provides assistance to households with incomes and assets below fixed thresholds. Although it is the largest entitlement program in the social safety net, little is known about the effect of food stamps on stabilizing fluctuations in household income and consumption. To estimate the volatility of income and the attendant reduction in volatility due to food stamps we use data from the Panel Study of Income Dynamics over 1980-1999 along with a model of income that admits permanent and transitory components as well as random growth rate heterogeneity. We then specify a model relating income changes to …

Forage News [2003-01], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Happy New Year!
• Regional Grazing Conference Coming to Hannibal, Missouri
• Oops!!!
• Organic Agriculture Depends on Inorganic Nutrients
• 23^RD Alfalfa Conference Set for February 20
• Upcoming Events

Educating Adolescents About Puberty: What Are We Missing?, Hatim A. Omar, Darby H. Mcelderry, Rana M. Zakharia

Pediatrics Faculty Publications

Adolescents undergo significant physical and cognitive changes during their pubertal development. These changes contribute to and impact their future development. Educating adolescents at an early age about their expected development decreases the possible anxiety associated with this period of life and also helps adolescents make better choices in regards to their sexuality. In order to assess the degree of education regarding pubertal development and sexuality, we conducted a survey of late adolescents (Median age 19 years) and parents of adolescents. A total of 409 adolescents (237 females, 172 males) and 124 parents completed the survey. 14.4% of teens (36.6% of …

Improving The Well Being Of At-Risk Families: Exploring Clients’ Perceptions Of Preventative Services, Lenore M. Mcwey

University of Kentucky Center for Poverty Research Discussion Paper Series

Low income and working poor families are exposed to tremendous stressors, which in turn can impede their ability to care for their children (Dyk, 2004). In 2000, reports of abuse and/or neglect of over five million children were made to Child Protective Services (CPS) Agencies (U.S. Department of Health and Human Services, 2002). These families are often termed “at-risk” because of the possibility that the children could be placed in foster care. One prevention strategy used to help at-risk families is in-home family therapy. The Young Investigator Award through the University of Kentucky Center for Poverty Research (UKCPR) enabled me …

Pharmaceutical Patents And Trips: A Comparison Of India And South Africa, Stephen Barnes

Kentucky Law Journal

No abstract provided.