Digital Commons Network^™

Development Forecast: The Fiscal Effects On Property Taxes And Occupational License Fees And The Social Costs And Benefits Of Urban Redevelopment In Lexington-Fayette County, Kentucky, Tony J. Stoeppel

MPA/MPP/MPFM Capstone Projects

Real estate development has effects on the publicly recorded property valuation of a parcel. The extent of the relationship in Lexington-Fayette County demands further analysis. Redevelopment also has unintended social costs the public may be forced to bear. This study presents estimates of the fiscal impact a redevelopment project has on the local tax revenues. The study population used for analysis includes redevelopment projects completed within the last six years in the downtown Lexington area. The research attempts to formalize a relationship among the incremental change in the publicly recorded value, the cost of redevelopment, and the distance the project …

Economic Analysis Of Kentucky Being A Part Of The National Lambda Rail, Chithra Perumal

MPA/MPP/MPFM Capstone Projects

Electronic connectivity and information network systems form a major part of the overall modern research infrastructure. High capacity networks allow for the sharing vast amounts of data between research laboratories, analysis of complex images, and other demanding computer applications. The major electronic information network that is being established in the USA to improve electronic communication in the research field is the National Lambda Rail (NLR). NLR is a nationwide broad bandwidth computing network used by leading research institutions. NLR provides national scale infrastructure for research and experimentation. Most of the member states of NLR have high ranking in terms of …

Childhood And Adolescent Obesity: Nationwide Pediatric Healthcare Provider Practices And Their Role In Treatment And Prevention Of The Obesity Epidemic, Alison Farley

MPA/MPP/MPFM Capstone Projects

The purpose of this research is to explore screening and treatment patterns as well as the underlying provider confidence in their decision-making related to the overweight and obese child and adolescent patient. The screening and treatment of obesity in the child and adolescent population are affected by complex social implications and physical side effects. Without a clear consensus on screening, diagnosis and alternative treatment plans, healthcare providers will not maximize the opportunity to provide primary and secondary prevention to the growing epidemic.

Statistical analysis of secondary survey data was conducted to explore screening and treatment patterns as well as the …

A New Comprehensive Methodology For The Evaluation Of Product Sustainability At The Design Stage Of Consumer Electronics Products, Niranjali De Silva

University of Kentucky Master's Theses

The aim of this thesis is to investigate and generate quantifiable measures of sustainability elements that apply to manufactured products in terms of environmental, social and economic benefits. This paper presents a new comprehensive methodology for sustainability evaluation of a new product at the design and development stage focusing on consumer electronics products through a Sustainability Scoring method. A new product is evaluated for its integral elemental and the overall sustainability contents impacting the product when it reaches the end-of-life by considering the entire life-cycle including the effective residual use of recovered materials in the subsequent life-cycles of the same …

Examining Flow States And Motivational Perspectives Of Ashtanga Yoga Practitioners, Leslie Lynn Phillips

University of Kentucky Doctoral Dissertations

Flow state refers to an optimal psychological experience and is associated with a number of experiential qualities one of which is complete absorption in the task at hand. Self-determination theory provides a framework for examining the relation between different types of motivation and flow because it distinguishes among different forms of motivation based on the degree that they can be considered self-determined. Although flow has been studied among athletes and, to a lesser degree, exercisers, no studies have focused on the flow experiences of yoga practitioners. Yoga, which originated in India, has been gaining popularity in the United States. The …

Predicting The Location And Duration Of Transient Induced Low Or Negative Pressures Within A Large Water Distribution System, Richard C. Svindland

University of Kentucky Master's Theses

Surge modeling is a tool used by engineers and utility owners in determining the surge pressures or transients that may result from routine pump and valve operations. Recent surge modeling work has focused on low and/or negative pressures within water distribution systems and how those occurrences could lead to intrusions. Effective surge modeling is needed in order to determine if the intrusion potential exists and what mitigation is needed to prevent intrusions. This work focuses on the generally unexplored area of using surge models to predict the location and duration of transient induced low and/or negative pressures within large complex …

The Effect Of Polychlorinated Biphenyls On Liver Tumor Promotion: A Role For Kupffer Cells?, Rodica Petruta Bunaciu

University of Kentucky Doctoral Dissertations

Polychlorinated biphenyls (PCBs) are ubiquitious lipophilic environmental pollutants. At least some of the PCB congeners and mixtures are hepatic tumor promoters. The mechanisms are not fully understood and might be multifactorial Besides being the most abundant congener in the environment, 2,2,4,4,5,5-hexachlorobiphenyl (PCB-153), has been previously shown to increase hepatocyte proliferation 48h after exposure in rats. The goal of this study was to determine whether hepatic Kupffer cells are important in the promoting activity of PCBs. The hypothesis of this study was that modulation of Kupffer cell activity by PCBs may contribute to PCB-induced liver tumor promotion. The experimental approach consisted …

Modulation Of The Adrenal Medullary Response To Stress By Estradiol In The Female Rat, Julye Marie Adams

University of Kentucky Doctoral Dissertations

The present study has established that physiological concentrations of estradiol can modulate stress-induced increases in plasma epinephrine (EPI). In anesthetized female rats, insulin-induced hypoglycemia (0.25 U/kg) increased plasma EPI concentration to a significantly greater extent in 14-day ovariectomized (OVEX) rats compared to sham-operated controls. In 17-estradiol (E2)-replaced OVEX rats, the hypoglycemia-induced rise in plasma EPI was significantly reduced compared to OVEX rats. This suppression was due to both decreased adrenal medullary output and increased clearance of EPI. Adrenal venous EPI concentration was significantly reduced in OVEX+E2 rats, suggesting that EPI secretion from the adrenalmedulla was decreased by E2 replacement. The …

Modeling And Optimization Of Machining Performance Measures In Face Milling Of Automotive Aluminum Alloy A380 Under Different Lubrication/Cooling Conditions For Sustainable Manufacturing, Abhijit Dilip Kardekar

University of Kentucky Master's Theses

The use of cutting fluids in machining process is very essential for achieving desired machining performance. Due to the strict environmental protection laws now in effect, there is a wide-scale evaluation of the use of cutting fluids in machining. Consequently, minimal quantity lubrication (MQL), which uses very small quantity of cutting fluids and still offers the same functionality as flood cooling, can be considered as an alternative solution. This thesis presents an experimental study of face milling of automotive aluminum alloy A380 under four different lubrication/cooling conditions: dry cutting, flood cooling, MQL (Oil), and MQL (Water). Experiments were design using …

Parent-Child Storytelling During Joint Picture-Book Reading And Relation To Language Scores Of Children With Adhd, Melinda A. Leonard

University of Kentucky Master's Theses

Three questions were investigated in the current study. First, do children with ADHD have language deficiencies in comparison to non-referred peers? Second, are there diagnostic group differences in parent and child storytelling when interacting in a joint picture-book setting or in parent reported home literacy habits? Third, are these differences related to child language scores? Parents of 25 children with ADHD and 39 comparison children, average age 7 years 6 months, told their children a story based on a wordless picture-book, and children then retold the story to an examiner without using the book. In addition, children made up two …

A Comparison Of Syntax Training For Students With Developmental Disabilities Utilizing Clinician-Directed Versus Self-Determined Session Paradigms, Jane O'Regan Kleinert

University of Kentucky Doctoral Dissertations

Self-determination is the ability to control one’s life and to actively participate in the decisions which affect the direction of one’s life. This ability is considered a critical life skill for individuals with developmental disabilities. The ability to make choices, plan, and self-evaluate are among the primary skills included in the development of self-determination. Currently, there is very limited emphasis on the importance of self-determination in the literature of communication disorders. This study was designed to determine if a teaching paradigm which incorporates key elements of self-determination is as or more effective and efficient in teaching syntax than a traditional, …

Etiology Of Patellofemoral Pain Syndrome: A Proximal Link To A Distal Problem, Lori Ann Bolgla

University of Kentucky Doctoral Dissertations

Patellofemoral pain syndrome (PFPS) is one of the most common, but least understood, knee disorders. Fulkerson (1997) believes that pathology may result from an excessive valgus force being applied to the patella. Researchers have historically examined quadriceps strength and neuromuscular activity and knee kinematics. However, results from these works have not provided conclusive answers. Powers (2003) has theorized that other structures can influence knee function, and researchers have shown that PFPS subjects can exhibit hip weakness and demonstrate altered hip kinematics during functional activities. Although they provide preliminary evidence regarding hip influences, investigations that simultaneously examine hip and knee function …

Phylogenetic Analysis Of Kentucky Strains Of Xylella Fastidiosa, J. Nicole Mundell

University of Kentucky Master's Theses

Phytopathogenic bacterium, Xylella fastidiosa, causes a number of economically important diseases, including Pierces disease (PD) of grape and bacterial leaf scorch (BLS) of a number of landscape trees. In Kentucky (KY), BLS affects a number of shade trees including many oak and maple species. In 2001, PD was diagnosed in grapevines in western KY. Xylella fastidiosa is also detected in many asymptomatic landscape plants and grasses. It was the goal of this research to identify hosts of X. fastidiosa around KY and use phylogenetic analysis to compare sequences of the 16S rDNA and gyrase B (gyrB) genes between samples. This …

Characterizing Sensory Processing In Autism Spectrum Disorders, Scott David Tomchek

University of Kentucky Doctoral Dissertations

Rationale: Autism is a neurodevelopmental disorder with onset prior to the age of three years characterized by qualitative impairments in social interaction and communication skill, along with a restricted repetitive and stereotyped pattern of behavior, interests, and activities. In addition to these core diagnostic features, aberrant sensory responding has also been widely reported in the literature describing children and adolescents with autism spectrum disorders (ASD). Aberrant sensory processing has, however, been infrequently studied compared to communication and cognition in autism and existing studies have had multiple methodological deficiencies, especially with sampling procedures. Purpose. The purpose of this study is to …

Mechanism Of Cancer Selective Apoptosis By Par-4, Sushma Gurumurthy

University of Kentucky Doctoral Dissertations

Despite distinct dissimilarities, diverse cancers express several common pro-tumorigenic traits. We present here evidence that the pro-apoptotic protein Par-4 utilizes one such common tumorigenic trait to become selectively activated and induce apoptosis in cancer cells. Elevated PKA activity noted in cancer cells activated the apoptotic function of ectopic Par-4 or its SAC domain, which induces apoptosis selectively in cancer cells and not in normal or immortalized cells. PKA preferentially phosphorylated Par-4 at the T155 residue within the SAC domain in cancer cells. Moreover, pharmacological-, peptide- or siRNA-mediated inhibition of PKA activity in cancer cells resulted in abrogation of both T155 …

Interactions Between Selenium And Polychlorinated Biphenyls (Pcbs), Divinia Nolasco Stemm

University of Kentucky Doctoral Dissertations

This study investigated the interaction between polychlorinated biphenyls (PCBs) and selenium to explain the mechanism involved that could affect selenium metabolism and its anti-cancer property. PCBs congeners and mixtures were previously found to reduce hepatic Se and Se-dependent glutathione peroxidase activity. I hypothesized that certain PCB congeners affect selenium metabolism in the rat liver resulting in diminished antioxidant capacity of selenoproteins, which could alter the ability of Se to protect against PCBs induced tumor promotion. In the first study, the influence of 3,3,4,4-tetrachlorobiphenyl (PCB 77) on hepatic Se and glutathione peroxidase (GPx1) activity as well as cytochrome P450 1A1 induction …

Kentucky Feeder Cattle Price Analysis: Models For Price Predictions And Grazing Management, Roger Wayne Eldridge

University of Kentucky Master's Theses

Kentucky plays an important role in the complex U.S. beef cattle industry. Thisstudy focused on the feeder cattle production sector of Kentucky's beef cattle industry.Primarily a cow-calf state with a substantial backgrounding sector, Kentucky is a largesupplier of feeder cattle to the cattle finishing sector. Price relationships within themarket for Kentucky feeder cattle were examined using historical price data fromKentucky livestock auction markets. This research revealed many interesting pricerelationships that Kentucky producers may use in order to increase the profitability of thecow-calf and/or backgrounding operations. A segment of this research includes aGrazing Management Decision Tool which was constructed to enable …

An Examination Of Dietary Amendments To Affect Phosphorus Utilization In Growing Pigs, Jorge Hernan Agudelo-Trujillo

University of Kentucky Doctoral Dissertations

For economical and ecological reasons, efficiency and profitability ofswine production relies heavily on the way pigs utilize key nutrients such as P,which is considered a potential pollutant of water ecosystems. Although cerealgrains and oilseed meals contain enough P to fulfill the biological needs of pigs,most of this P is tightly bound as phytate. As pigs do not have enough phytase(PHY) to cleave P from phytate, it is excreted in the feces. To prevent adeficiency, diets have traditionally been supplemented with highly availableinorganic sources of P. Today, an environmentally-friendly alternative is tosupplement diets with PHY.Growth promoting antibiotics are also used to …

Human Cardiovascular Responses To Artificial Gravity Training, Michael Brian Stenger

University of Kentucky Doctoral Dissertations

Human cardiovascular adaptations to microgravity include decreased plasma volume, exercise capacity, baroreflex function as well as decreased orthostatic tolerance upon return to a gravity environment. Several countermeasures have been proposed and tested, although currently none have been developed to prevent post-spaceflight orthostatic intolerance (OI). Artificial gravity (AG) generated by short-radius centrifugation (SRC) has been proposed as a countermeasure to OI as well as other cardiovascular alterations. Methods: Fifteen men and fourteen women underwent three weeks of daily (5 days a week) exposure to intermittent (1.0 to 2.5 Gz) artificial gravity on a 1.9m human powered centrifuge (HPC) at the NASA …

A Comparison Between Masticatory Muscle And Temporomandibular Joint Pain Patients With Regard To The Prevalence And Impact Of Post-Traumatic Stress Disorder Symptoms, Elizangela Bertoli

University of Kentucky Master's Theses

The purpose of this study was to evaluate masticatory muscle (MM) and temporomandibular joint (TMJ) pain patients regarding the prevalence of Posttraumatic Stress Disorder (PTSD) symptoms, and evaluate the level of psychological dysfunction and its relationship to PTSD symptoms in these patients. This study included 445 adult patients (male = 42, female = 403). Psychological questionnaires included the Symptom Check List-90-Revised (SCL-90-R), the Multidimensional Pain Inventory, the Pittsburgh Sleep Quality Index and the PTSD Check List Civilian. The total sample of patients was divided into two major groups: The MM group (n=242) and TMJ group (n=203). Each group was divided …

Can Interactivity Make A Difference? Effects Of Interactivity On Young Adults' Comprehension Of Online Health Content, Mia Liza Alcantara Lustria

University of Kentucky Doctoral Dissertations

The Internet is growing in popularity as a health information sourceespecially among young adults. Interactivity has been pinpointed as the keyfeature that makes the Internet a potentially powerful health communicationtool. It is being heralded as a hybrid channel that has the capacity not only todisseminate health information to mass audiences both asynchronously andsynchronously, but also has the capacity to provide an engaging and stimulatingenvironment that can promote exploratory learning and active processing ofinformation. Despite these exciting claims, there is still a dearth of theoreticallydrivenempirical studies providing support for or against these assumptions. Westill know very little about how interactive technologies …

Mediating Indigenous Identity: Video, Advocacy, And Knowledge In Oaxaca, Mexico, Laurel Catherine Smith

University of Kentucky Doctoral Dissertations

In the southern Mexican state of Oaxaca, many indigenous communities further their struggles for greater political and cultural autonomy by working with transnational non-governmental organizations (NGOs). Communication technology (what I call comtech) is increasingly vital to these intersecting socio-spatial relations of activism and advocacy. In this dissertation, I examine how comtech offer indigenous individuals and organizations with the means for visualizing their political-cultural agendas. Approaching the access and use of comtech, especially video technologies, as a partial and situated technoscience, I inquire into how and why these activities reconfigure the production and evaluation of authoritative knowledge about indigenous peoples, places, …

Identity In Evangelical Ukraine: Negotiating Regionalism, Nationalism, And Transnationalism, Esther Grace Long

University of Kentucky Doctoral Dissertations

This dissertation examines identity formation among evangelical Protestants in contemporary Ukraine. The overarching question is this: how do Ukrainian evangelicals view themselves and their churches in the context of Ukrainian regionalism, Ukrainian nationalism, and religious transnationalism? This question demands a closer look at Ukrainian regional variation, the status of Ukrainian national identity among evangelical practitioners, and the process of religious transnationalism, including how evangelicals perceive the West. This project is primarily based on qualitative research methods carried out over a ten month period. Field methods included participant observation, focus group interviews, and individual interviews. A set of maps produced by …

Innovative Product Design For Sustainability Enhancement In Aluminum Beverage Cans Based On Design For Sustainability Concepts, Jason Chun Tchen Liew

University of Kentucky Master's Theses

A new methodology for innovative product development based on the application of sustainability principles for the entire life-cycle of a product and beyond is developed. This involves an analysis of multi-life cycle material flow leading towards perpetual life products, making it truly sustainable. In order to achieve the function of such a sustainable product, it has to fulfill the concept of 6R (Recover, Reuse, Recycle, Redesign, Reduce and Remanufacture), which are composed of 6 stages of material flow in a products life, as opposed to the traditional 3R (Reduce, Reuse, Recover) concept. We apply the 6R concept in designing a …

To Forgive Is Divine, But Is It Always Helpful? Examining The Effects Of Brief Forgiveness Instructions In Helping Female Victims, Michelle K. Cardi

University of Kentucky Master's Theses

The purpose of the present study was to examine whether women who have been victimized can have a decrease in their negative affect by being exposed to the suggestion of one of two dimensions of forgiveness. The study also examined the moderating effect of several personality variables on participants reactions to the intervention. Seventy-nine women were given several personality and affect questionnaires before and after they listened to instructions for either granting forgiveness (interpersonal), letting go of their negative affect (intrapsychic), or relaxation (control). Results indicated that focusing on granting forgiveness was associated with more negative affect than the other …

Examining The Validity Of The Life History Calendar, Leslie-Ann C. Robertson Toney

University of Kentucky Master's Theses

This study examined validity of the Life History Calendar by comparing retrospective and prospective reports of adolescent substance use. Agreement was calculated using kappa and phi coefficients for dichotomous variables, and Bivariate correlations for average substance use. Effects of potential personality, psychopathology, and demographic moderators on agreement were assessed through hierarchical regression analyses and curvilinear relations determined. Results reflected moderate agreement between retrospective and prospective reports of substance use, moderated by personality and psychopathology variables, particularly Agreeableness, symptoms of antisocial personality disorder, and symptoms of substance abuse. Agreement between retrospective and prospective reports was adequate for reports of alcohol and …

The Use Of A Whole Genome Scan To Find A Genetic Marker For Degenerative Suspensory Ligament Desmitis In The Peruvian Paso Horse, Diane I. Strong

University of Kentucky Master's Theses

Degenerative suspensory ligament desmitis (DSLD) is a debilitating disease of connective tissues seen in many breeds but has become prevalent in the Peruvian Pasohorse. DSLD is believed to be a genetic disorder caused by one primary founder and most likely has a recessive mode of inheritance although a dominant or co-dominant mode of inheritance has not been ruled out.

A genome scan using 259 microsatellite markers was used to test for linkage disequilibrium between one or more markers and DSLD. Two groups of Peruvian Pasohorses were selected from one population including the US and Canada. The only difference between the …

The Intersection Of Filial Piety And Cultural Dissonance: Intergenerational Exchanges Among Khmer Families In The United States, Denise Clark Lewis

University of Kentucky Doctoral Dissertations

In this thesis I describe Khmers negotiations of circumstances surrounding the disassembly, reconstruction, and redefinition of Khmer identity from their homeland in Cambodia to a traditional Khmer village recreated in the United States. Using a framework derived from a constructivist perspective, I have placed processes of negotiation and identity transformation within the lived context of Khmers lives. Thus, a holistic understanding of the interrelatedness of multiple changes in Khmerness is made possible. Ethnographic data collected between 1997 and 1999, through participant-observation and interviews, inform this study. Findings from this study reveal three levels of identity transformation as told by members …

Effects Of Weight Loss On Visceral Adiposity And Metabolic Adaptations In Diabetic Versus Non-Diabetic Women, Elizabeth C. Konz

University of Kentucky Doctoral Dissertations

Obesity increases the risk for the development of cardiovascular disease, type 2 diabetes and other co-morbid conditions. Type 2 diabetes also is often associated with excessive visceral abdominal fat. Weight loss in obese individuals decreases the risk for developing the co-morbid conditions. Individuals with type 2 diabetes often have a greater difficulty in controlling these complications compared to individuals without type 2 diabetes. The purpose of this study was to evaluate adherence to a medically-supervised low-energy diet (LED) weight loss program and changes in body composition and metabolic parameters after weight loss in women with and without type 2 diabetes. …

Analysis Of Oligonucleotide Array Experiments With Repeated Measures Using Mixed Models, Hao Li, Constance L. Wood, Thomas V. Getchell, Marilyn L. Getchell, Arnold J. Stromberg

Statistics Faculty Publications

BACKGROUND: Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients with Alzheimer's disease) or absence (Control) of the disease, and brain regions including olfactory bulb (OB) or cerebellum (CER). In the design considered in this manuscript, OB and CER are repeated measurements from the same subject and, hence, are correlated. It is critical to identify sources of variability in the analysis of oligonucleotide array experiments with repeated measures and correlations among data points have to be considered. In addition, multiple testing problems are more …