Digital Commons Network^™

Intimate Partner Violence And Disabilities Among Women Attending Family Practice Clinics, Ann L. Coker, Paige H. Smith, Mary Kay Fadden

CRVAW Faculty Journal Articles

Purpose: To estimate the frequency and type of disabilities preventing work among those experiencing intimate partner violence (IPV) compared with those never experiencing IPV.

Methods: We used a large cross-sectional survey of women, ages 18–65, attending family practice clinics from 1997 through 1998. Participation included a 5–10-minute in-clinic survey assessing IPV experience and a longer telephone survey assessing health status and chronic disabilities that prevented work outside the home or housework.

Results: Of 1,152 eligible women surveyed, 54% experienced some type of IPV, and 24% were currently in a violent relationship. Women who had ever experienced IPV …

Seventeen Amino Acid Peptide (Peptide P) For Treating Ischemia And Reperfusion Injury, Peter R. Oeltgen, Mark S. Kindy

Molecular and Cellular Biochemistry Faculty Patents

Peptide P, having the amino acid sequence Tyr-D-Ala-Phe-Ala-Asp-Val-Ala-Ser-Thr-Ile-Gly-Asp-Phe-His-Ser-Ile-NH2-SEQ ID NO:1, is useful to treat ischemia.

Positive Youth Development And 4-H: Making The Connection, Ken Jones

Community and Leadership Development

No abstract provided.

Dump Truck Driver Crushed Between Trackhoe And Dump Truck, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Motor Vehicle

On November 11, 2004, a 33-year-old male dump truck driver died when he was crushed between the driver’s side of the dump truck and the swinging counter-weight of an excavator (trackhoe). His dump truck became stuck in mud after the trackhoe loaded dirt into it so he walked to the on-site office and informed the owner. The owner located a bulldozer on site and drove it to the dump truck while the driver retrieved a chain from his personal pickup truck. The owner raised the blade so the driver could attach the chain to it. Raising the blade of the …

Evaluation Of Stature Development During Childhood And Adolescence In Individuals With Familial Hypophosphatemic Rickets, Mauro M. S. Borghi, Verônica Coates, Hatim A. Omar

Pediatrics Faculty Publications

This review was conducted to study the diagnosis, treatment, and growth progression in infants and adolescents with familial hypophosphatemic rickets. The bibliographic search was carried out utilizing the electronic databases MEDLINE, OVID, and LILACS and by direct research within the last 15 years using the keywords rickets, familial hypophosphatemia, vitamin D deficiency, stature growth, childhood, and adolescence. Article selection was done by comparing the evaluation of the growth in patients with familial hypophosphatemic rickets, including the variables that might affect them, for possible future therapeutic proposals. It is concluded that the most significant fact in the treatment of familial hypophosphatemic …

Poverty And Fertility In The American South, Leonard M. Lopoo

University of Kentucky Center for Poverty Research Discussion Paper Series

This project first reports descriptive evidence of the characteristics of mothers in the American South and compares them to mothers in other regions of the country. Women in the South (and West) tend to have their children at younger ages than those in the Midwest and Northeast. Mothers in the South (and West) also have much lower levels of education and are more likely to be African American or Hispanic compared to women in the Midwest and Northeast. Next, this paper attempts to link the characteristics of the mothers in the American South to the high rates of poverty there. …

Agricultural Situation And Outlook Fall 2005, Matt Ernst, Kenneth H. Burdine

Agricultural Situation and Outlook

No abstract provided.

Economic Costs Of Low Safety Belt Usage In Motor Vehicle Crashes In Kentucky, Michael Singleton, Qing Xiao, Kenneth R. Agent

Kentucky Transportation Center Research Report

By passing legislation in 2006 to mandate primary enforcement of the Kentucky state law requiring safety belt use for motor vehicle occupants, the state could expect to realize an overall savings of at least $118 million in direct medical costs over the ten-year period from 2006 to 2015. Charges to Medicaid over that period would be about $34 million less than under the current secondary enforcement model. In addition, there would be at least $67 million saved in medical costs to commercial insurers, $2.3 million to Medicare, $3.3 million to Worker’s Compensation, and $11.2 million to other sources.

These savings …

Murine Monoclonal Anti-Idiotype Antibody 11d10 And Methods Of Use Thereof, Malaya Chatterjee, Kenneth A. Foon, Sunil K. Chatterjee

Microbiology, Immunology and Molecular Genetics Faculty Patents

The present invention provides a monoclonal anti-idiotype antibody 11D10 that elicits an immune response against a specific epitope of a high molecular weight mucin of human milk fat globule (HMFG) and a hybridoma that produces 11D10. The hybridoma that produces 11D10 was selected by specific procedures. 11D10 induces an immunological response to HMFG in nice, rabbits, monkeys and patients with advanced HMFG-associated tumors. This invention provides compositions derived from polynucleotide sequences encoding the variable light and/or variable heavy regions of monoclonal anti-idiotype antibody 11D10, as well as polypeptides encoded thereby. The invention also provides compositions which can be used in …

Cis-2,6-Disubstituted Piperidines For The Treatment Of Psychostimulant Abuse And Withdrawal, Eating Disorders, And Central Nervous System Diseases And Pathologies, Linda P. Dwoskin, Peter A. Crooks, Marlon D. Jones

Pharmaceutical Sciences Faculty Patents

Cis-2,6-disubstituted piperdine analogs, or lobeline analogs, having the general formula...

To see the remainder of this abstract, please download this patent.

Cleaner Falls 35 Feet To His Death Through Temporary Roof Opening, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Falls

On February 23, 2004, a 50-year-old male cleaner died when he fell approximately 35 feet through a temporary roof opening and was impaled on a piece of equipment on the factory floor. He had been cleaning an exhaust fan on a factory roof with a pressure washer. He and two coworkers had removed the fan from its casing creating a temporary roof opening and set the fan beside the roof opening for cleaning. Facing the fan with his back to the opening, the cleaner apparently stepped backwards and fell through the opening. He fell onto a 1200-ton die-casting machine on …

Practicing Under The New Bankruptcy Code: A Nuts & Bolts Workshop, Office Of Continuing Legal Education At The University Of Kentucky College Of Law

Continuing Legal Education Materials

Materials from Practicing Under the New Bankruptcy Code: A Nuts & Bolts Workshop (The Bankruptcy Abuse Prevention and Consumer Protection Act of 2005) held by UK/CLE in September 2005.

Poverty, Race And The Contexts Of Achievement: Examining Educational Experiences Of Children In The American South, Maryah Stella Fram, Julie Miller-Cribbs, Lee Van Horn

University of Kentucky Center for Poverty Research Discussion Paper Series

This paper reports findings of a study examining child-, classroom-, and school-level factors that effect academic achievement among public school children in the South. Using ECLS-K data, we compare and contrast the learning environments in high/low minority and high/low poverty schools. A sizeable minority of Southern children attend schools that are race and/or class segregated; on multiple dimensions these schools are less desirable than are schools attended by more privileged children, and children attending these schools have lower levels of academic achievement. Results from 3-level random intercepts models show that a range of child and family factors, as well as …

Forage News [2005-09], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Scott County to Host Fall Grazing School
• Now is the Time to Test
• Economics of Grazing Stocker Cattle as a Sustainable Alternative to Row Crops
• Roundup Ready Alfalfa
• Novel Endophyte Tall Fescue
• Is It Too Late to Stockpile This Year?
• KFGC Awards
• KFGC Executive Committee to Meet September 6
• Wisconsin Grazing Dairy Farms
• Upcoming Events

The Chemical Species Of Aluminum Influences Its Paracellular Flux Across And Uptake Into Caco-2 Cells, A Model Of Gastrointestinal Absorption, Yuzhao Zhou, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

Aluminum (Al) can cause neurotoxicity, a low-turnover osteomalacia, and microcytic anemia. To test the null hypothesis that the chemical form (species) of Al does not influence its mechanism or rate of absorption from the gastrointestinal tract, Al flux across and uptake into Caco-2 cells was investigated. Caco-2 cells were grown on porous membranes mounted in vertical diffusion chambers or in 35-mm-diameter plastic cell culture dishes. When 8 mM ²⁷Al was introduced as the ion, citrate, maltolate, fluoride, or hydroxide, the apical to basolateral apparent permeability (P_app) of Al correlated highly with the P_app of lucifer yellow …

Lextran Support Project: Strategic Planning Support For Lextran Visioning, Lenahan O'Connell, Ted Grossardt

Kentucky Transportation Center Research Report

In October 2003, LexTran, the City of Lexington’s public transportation provider, was undergoing a management transition. It sought the assistance of the Kentucky Transportation Center for strategic planning and visioning. This project produced four deliverables: (1) a series of public meetings facilitated by the Kentucky Transportation Center on rider and other stakeholder attitudes toward LexTran and its general performance; (2) an environmental scan comparing LexTran to similar transit providers on operating efficiency, ridership, funding sources, and other characteristics; (3) A GIS database containing census data and other information useable for the analysis of proposed routes; and (4) a PowerPoint presentation …

Cpg Oligodeoxynucleotides Stimulate Cord Blood Mononuclear Cells To Produce Immunoglobulins., Cheri D Landers, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

CpG oligodeoxynucleotides (ODNs) stimulate adult B cells leading to cellular proliferation and immunoglobulin production. It is unknown if CpG-ODNs similarly stimulate neonatal human B cells. Neonates have immature immune responses and are poorly responsive to thymus independent antigens such as polysaccharides. We determined umbilical cord cells' response to CpG-ODNs. Adult and umbilical cord B cells produced similar amounts of IgM (adult 1371 +/- 352 vs. cord 1873 +/- 1084 ng/ml) in response to CpG-ODN stimulation. Although CpG-ODN was able to stimulate adult IgG and IgA production, cord cells produced less IgG (153 +/- 58 vs. 10 +/- 2.5 ng/ml) and …

Effects Of Commercial Diazinon And Imidacloprid On Microbial Urease Activity In Soil And Sod, C. W. Ingram, Mark S. Coyne, David W. Williams

Plant and Soil Sciences Faculty Publications

Diazinon [O,O-diethyl O-2-isopropyl-6-methyl(pyrimidine-4-yl) phosphorothioate] and imidacloprid [1-(1-[6-chloro-3-pyridinyl]methyl)-N-nitro-2-imidazolidinimine] are applied to lawns for insect control simultaneously with nitrogenous fertilizers such as urea, but their potential effect on urease activity and nitrogen availability in turfgrass management has not been evaluated. Urease activity in enzyme assays, washed cell assays, and soil slurries was examined as a function of insecticide concentration. Intact cores from field sites were used to assess the effect of insecticide application on urease activity in creeping bentgrass (Agrostis palustris Huds.) and bluegrass (Poa pratensis L.) sod. Bacterial urease fromBacillus pasteurii and plant …

Effects Of Dietary Curcumin Or N-Acetylcysteine On Nf-Kappab Activity And Contractile Performance In Ambulatory And Unloaded Murine Soleus, Mehran Farid, Michael B. Reid, Yi-Ping Li, Eric Gerken, William J. Durham

Physiology Faculty Publications

BACKGROUND: Unloading of skeletal muscle causes atrophy and loss of contractile function. In part, this response is believed to be mediated by the transcription factor nuclear factor-kappa B (NF-kappaB). Both curcumin, a component of the spice turmeric, and N-acetylcysteine (NAC), an antioxidant, inhibit activation of NF-kappaB by inflammatory stimuli, albeit by different mechanisms. In the present study, we tested the hypothesis that dietary curcumin or NAC supplementation would inhibit unloading-induced NF-kappaB activity in skeletal muscle and thereby protect muscles against loss of mass and function caused by prolonged unloading.

METHODS: We used hindlimb suspension to unload the hindlimb muscles of …

C-Jun N-Terminal Kinase (Jnk) Is Required For Survival And Proliferation Of B-Lymphoma Cells, Murali Gururajan, Roger Chui, Anbu K. Karuppannan, Jiyuan Ke, C. Darrell Jennings, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Several primary murine and human B lymphomas and cell lines were found to constitutively express high levels of the activated form of c-jun N-terminal kinase (JNK), a member of the mitogen-activated protein (MAP) kinase family. Proliferation of murine B lymphomas CH31, CH12.Lx, BKS-2, and WEHI-231 and the human B lymphomas BJAB, RAMOS, RAJI, OCI-Ly7, and OCI-Ly10 was strongly inhibited by SP600125, an anthrapyrazolone inhibitor of JNK, in a dose-dependent manner. The lymphoma cells underwent apoptosis and arrested at the G2/M phase of cell cycle. Furthermore, JNK-specific small interfering RNA (siRNA) inhibited the growth of both murine and human B lymphomas. …

Methods And Compositions Useful In Enhancing Oxygen Delivery To Cells, Elaine L. Jacobson, Myron Jacobson, Jaber G. Qasem, Hyuntae Kim, Moonsun Kim

Graduate Center for Nutritional Sciences Faculty Patents

The invention discloses compositions and methods which are useful in improving delivery of oxygen to cells. The compositions require at least one derivative of a compound. The derivatives are chosen to have log P values below about 6.0.

Runx-Dependent Expression Of Pkc Is Critical For Cell Survival In The Sea Urchin Embryo, Carrie Dickey-Sims, Anthony J. Robertson, Dawn E. Rupp, John J. Mccarthy, James A. Coffman

Physiology Faculty Publications

BACKGROUND: Runx transcription factors play critical roles in the developmental control of cell fate and contribute variously as oncoproteins and tumor suppressors to leukemia and other cancers. To discover fundamental Runx functions in the cell biology of animal development, we have employed morpholino antisense-mediated knockdown of the sea urchin Runx protein SpRunt-1. Previously we showed that embryos depleted of SpRunt-1 arrest development at early gastrula stage and underexpress the conventional protein kinase C SpPKC1.

RESULTS: We report here that SpRunt-1 deficiency leads to ectopic cell proliferation and extensive apoptosis. Suppression of the apoptosis by pharmacological inhibition of caspase-3 prevents the …

Expression Of Cd68 And Macrophage Chemoattractant Protein-1 Genes In Human Adipose And Muscle Tissues: Association With Cytokine Expression, Insulin Resistance, And Reduction By Pioglitazone, Gina B. Di Gregorio, Aiwei Yao-Borengasser, Neda Rasouli, Vijayalakshmi Varma, Tong Lu, Leslie M. Milrd, Gouri Ranganathan, Charlotte A. Peterson, Robert E. Mcgehee Jr., Philip A. Kern

Clinical and Translational Science Faculty Publications

To examine the role of adipose-resident macrophages in insulin resistance, we examined the gene expression of CD68, a macrophage marker, along with macrophage chemoattractant protein-1 (MCP-1) in human subcutaneous adipose tissue using real-time RT-PCR. Both CD68 and MCP-1 mRNAs were expressed in human adipose tissue, primarily in the stromal vascular fraction. When measured in the adipose tissue from subjects with normal glucose tolerance, covering a wide range of BMI (21-51 kg/m²) and insulin sensitivity (S_I) (0.6-8.0 × 10^-4 min^-1 · μU^-1 · ml^-1), CD68 mRNA abundance, which correlated with the number …

A Brief History And Current Status Of A Dental Therapy Initiative In The United States, David A. Nash, Ron J. Nagel

Oral Health Science Faculty Publications

No abstract provided.

Meeting Kentucky’S Transportation Needs And Priorities: Citizens’ Perceptions And Recommendations, Donald L. Hartman, Merl Hackbart, Juita-Elena (Wie) Yusuf, Candice Y. Wallace

Kentucky Transportation Center Research Report

This study was designed to (1) consider the role of public input in the transportation planning process; (2) obtain citizen perceptions of system needs and develop priorities in the state of Kentucky; and (3) use that experience (and the experiences of other states) to provide recommendations for ways to enhance the role of public input in Kentucky’s transportation planning. Telephone survey of Kentucky adults and focus groups of community leaders were utilized to gauge the public’s attitudes and perceptions regarding Kentucky’s transportation needs, issues and priorities, and system satisfaction. The findings from the survey and the focus groups were compared …

Nurse Anesthetists In Southeastern Kentucky: A Survey Of Supply Versus Demand, Judy Owens, David A. Gross, Peggy Lewis

Center of Excellence in Rural Health Reports

Examines the geographic maldistribution of nurse anesthetists in Kentucky and the status of their positions and vacancies at all 19 hospitals in the southeastern part of the state. UK Center for Excellence in Rural Health-Hazard researchers found that southeastern Kentucky has 12.5 percent of Kentucky’s total population and performs 11.5 percent of the state’s total surgeries - but has only 6.5 percent of the state’s total resident nurse anesthetists.

Fiscal Policy And Local Economic Development, William Hoyt, John Garen

CBER Research Report

No abstract provided.

32nd Midwest/Midsouth Estate Planning Institute, Office Of Continuing Legal Education At The University Of Kentucky College Of Law

Continuing Legal Education Materials

Materials from the 32nd Midwest/Midsouth Estate Planning Institute held by UK/CLE in July 2005.

Spatial Variation Of Protein, Oil, And Starch In Corn, Samuel G. Mcneill, Michael D. Montross, Scott A. Shearer

Biosystems and Agricultural Engineering Faculty Publications

Significant spatial yield variations are known to exist in cornfields with different soil types, topsoil depth, and other variables. Similarly, variations might also be found among the highly valued chemical components (oil, protein, and starch) in corn kernels due to local differences in soil type, fertility, acidity/pH, organic matter, etc. This study quantified the spatial variability of protein, oil, and starch content of corn from two conventional cornfields and two high-oil cornfields. Whole ears were harvested by hand from 20 to 40 randomly selected locations within each field. A differential global positioning system (DGPS) receiver recorded the location of each …

Southeastern Law Librarian Summer 2005, Seaall

Newsletters

No abstract provided.