Digital Commons Network^™

Investigating Non-Functional Overreaching In Special Operations Tactical Training, Jeremy Alan Ross

Theses and Dissertations--Rehabilitation Sciences

Special Operations Forces (SOF) tactical training requires high levels of physical performance and psychological resilience. This training is often characterized by extreme temperatures and environments, extremely high levels of physical activity and large caloric deficits. As such, SOF personnel follow intense strength and conditioning (S&C) programs to enhance a wide range of athletic abilities. Such programs rely on a balance between training stress and recovery to allow for gradual improvement in physical ability over time, however it is unknown how to quantify tactical training stress in the context of a training program. This dissertation explores evidence related to how this …

Modeling And Analysis Of Amorphous Steel Transformer For Potential Loss Reduction In Power Systems., Daniel A. Muchow

Theses and Dissertations--Electrical and Computer Engineering

The energy consumed in power systems can be reduced directly by implementing new technologies and materials. The effort to reduce the carbon emissions expelled from the production of electrical energy has become a major focus. According to the U.S. energy Information Administration approximately 5% of all the electric generated and transmitted in the U.S. electrical grid is lost. The energy profile calculated from the usage of electrical power from all 50 states in 2021 is estimated to be 3.8 billion megawatts per hour, with a state average of just over 11 cents per MWh, producing just over 41.8 billion in …

Residual Next-Day Effects Of Alprazolam On Psychomotor Performance And Simulated Driving In Healthy Normal Adults, Stevie C. Roszkowski, Shanna Babalonis, Marion A. Coe, Paul Nuzzo, Michelle R. Lofwall, Laura C. Fanucchi, Sharon L. Walsh

Center on Drug and Alcohol Research Faculty Publications

The prevalence of drugged driving has increased in the United States. Some drugged driving may be unintentional as prescription medications used as sleeping aids, like zolpidem, cause impairment after the predicted duration of therapeutic action has elapsed. The aim of this study was to determine if nighttime administration of alprazolam, a drug commonly prescribed off-label as a sleeping aid, impacts driving performance the following day. Participants were healthy adults (n = 15) who completed a double-blind, double-dummy, within-subjects inpatient study examining the effects of nighttime administration of alprazolam (0.5, 1, and 2 mg), zolpidem (10 mg), and placebo on driving …

Cross-Species Comparisons Between Pigs And Mice Reveal Conserved Sex-Specific Intraspinal Inflammatory Responses After Spinal Cord Injury, Reena Kumari, Gabrielle V. Hammers, Robert H. Hammons, Andrew N. Stewart, Steven M. Maclean, Tracy Niedzielko, Lonnie E. Schneider, Candace L. Floyd, John C. Gensel

Spinal Cord and Brain Injury Research Center Faculty Publications

Objective Therapeutic translation is challenging in spinal cord injury (SCI) and large animal models with high clinical relevance may accelerate therapeutic development. Pigs have important anatomical and physiological similarities to humans. Intraspinal inflammation mediates SCI pathophysiology. The purpose of this study was to evaluate the effect of sex on inflammation and outcomes in a pig thoracic contusion/compression SCI model.

Methods Adult (gonad-intact) male and female Yucatan miniature swine were subjected to either SCI or sham (laminectomy-only) injury.

Results SCI caused locomotor dysfunction (measured with the Porcine Thoracic Injury Behavior Score) with some recovery over 6 weeks and limited tissue sparing …

Differential Speed And Accuracy Trade-Off In Working Memory Retrieval And Bilateral Precuneus Between Older Men And Women, Darlingtina K. Esiaka, Stephanie Strothkamp, Aghayeeabianeh Banafsheh, Lucas S. Broster, David K. Powell, Gregory Jicha, Yang Jiang

Behavioral Science Faculty Publications

Background

Despite various hypotheses, including differences in longevity, hormones, genetics, and neuroanatomy, the reasons for the higher prevalence of Alzheimer's disease in older women compared to men remain unclear. Emerging evidence suggests that the precuneus, a key region of the default mode network, is linked to internally focused processes like memory retrieval. We examined the relationship between precuneus volumes and task performance (accuracy and reaction time) during working memory retrievals in cognitively normal older adults.

Method

A cohort of older participants (N = 45; 25 women; M_age = 77) from the University of Kentucky Alzheimer's Disease Research Center …

Using Llms To Model Arguments In U.S. Supreme Court Briefs: Preliminary Report, Heng Zheng, Dexter Williams, Bertram Ludäscher

Information Science Faculty Publications

Supreme Court briefs can impact the decision-making of Supreme Court cases. We show how to represent the briefs for a U.S. Supreme Court case as a formal argument model that relies on the briefs’ existing structure. We explore how to generate argument models with large language models (LLMs) by using them to identify attacks between arguments.

Examining The Communication Work Of Women Who Have Tested Brca-Positive: “I Feel This Responsibility To Let People Know”, Summer C. Martin, Allison M. Scott, Anne M. Stone

Communication Faculty Publications

Inheriting a pathogenic variant in the BRCA1 or BRCA2 gene considerably increases a woman's risk levels for developing breast and ovarian cancer. In addition to serious physical health implications, women with a BRCA pathogenic variant may face psychosocial challenges, including those related to navigating the often demanding process of communicating about topics regarding BRCA with family and other social network members. Based on in-depth interviews with 24 women who tested BRCA-positive, we found that—consistent with the conceptualization of communication work articulated by Donovan-Kicken et al. (2012) as an extension of the theory of illness trajectories (Corbin & Strauss, 1988)—the labor …

Adolescents’ And Parents’ Perspectives On Using The Medsmarxt Families Intervention In Emergency Departments For Opioid Medication Safety Education: Mixed Methods Study, Olufunmilola Abraham, Sara Nadi, Irene Hurst

Pharmacy Practice and Science Faculty Publications

Background: The opioid crisis has significantly impacted adolescents and their families. This is attributed in part to increased opioid prescriptions in pediatric emergency departments (EDs) due to acute pain conditions and injuries. Although EDs frequently prescribe opioids, no effective preventative interventions have been implemented to educate adolescents and their families on safe opioid use. This study evaluates the MedSMA℞T Families intervention, which consists of an engaging serious game, Adventures in PharmaCity, and a personalized Family Medication Safety Plan (FMSP) with the aim of reducing opioid misuse and promoting opioid medication safety. The MedSMA℞T Families intervention was developed to educate adolescents …

Impact Of Fast Advancement And Early Fortification Of Enteral Feedings In Preterm Infants, A Retrospective, Observational Study., Enrique Gomez-Pomar, Holly Clarke, Jamie Adams

Pediatrics Faculty Publications

UNLABELLED: We aimed to evaluate the outcomes and growth of preterm infants at a Neonatal Intensive Care Unit that focuses on early initiation, fast advancement, and early fortification of enteral feeds.

METHODS: Retrospective study conducted at a community hospital level III NICU. Extensive feeding data and outcomes were collected by utilizing a NutritionIQ software application, NICUtrition®. Infants born between 26- and 34-weeks gestational age were included, whereas infants with congenital defects, deceased or with incomplete data were excluded. Frequency and descriptive statistical analysis were conducted using chi-square and Fisher's exact test. Unadjusted odds ratios were computed for categorical variables and …

Affordable Miniaturized Speckle Contrast Diffuse Correlation Tomography Device For Depth-Sensitive Mapping Of Cerebral Blood Flow In Rodents, Fatemeh Hamedi, Faezeh Akbari, Mehrana Mohtasebi, Chong Huang, Li Chen, Lei Chen, Guoqiang Yu

Biomedical Engineering Faculty Publications

Significance: Continuous and longitudinal monitoring of cerebral blood flow (CBF) is critical for understanding brain pathophysiology and guiding interventions. Although rodents are the primary models in neuroscience, existing imaging modalities often fail to provide the optimal combination of low cost, high spatiotemporal resolution, wide head coverage, and sufficient penetration depth for small-animal brain imaging.

Aim: Leveraging a clinical speckle contrast diffuse correlation tomography (scDCT) system, we aimed to develop an affordable, user-friendly, fast, and miniaturized scDCT (mini-scDCT) device tailored for depth-sensitive CBF imaging in small rodents.

Approach: The mini-scDCT replaces bulky and costly optoelectronic components with compact, low-cost alternatives while …

Pro-Government Militias And Political Instability: The Consequences Of Outsourced Regime Security, Ben J.A. Leo

Theses and Dissertations--Political Science

The state is often conceptualized as an entity with a monopoly over the use of force within some set borders. Yet, more and more frequently, states allow or deliberately create friendly non-state military organizations. Five-hundred and four of these groups, known as Pro-Government Militias (PGMs), were observed between 1981 and 2014 and were present in a little more than thirty percent of country-years in that timeframe (Carey et al. 2022). Moreover, while some groups are relatively small and weak, many constitute a considerable military force within their country and beyond. For example, the Xinjiang Construction Corps in China, which maintains …

How Sleep Disorders And Sleep Duration Impact Memory, Alexandria J. Sims

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

INTRODUCTION: Sleep duration and sleep disorders can cause changes in memory function as populations age. Previous studies have shown that disordered sleep is associated with increased risk of cognitive dysfunction and long and short sleep durations can cause memory impairment. This study studies aims to find if there is an association between sleep disorders and sleep duration and the impacts on memory.

METHODS: In this study, 3,478 participants aged 60 year and older from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 dataset were included in adjusted and unadjusted models, comparing the sleep disorders and sleep duration exposures to …

Comparative Effects Of Low- And High- Tech Visual Activity Schedules On Transition Latency In Young Children With Autism, Mikayla Nelson

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Low-technology (low-tech) and high-technology (high-tech) visual activity schedules (VAS) were implemented for transitions with three kindergarten males diagnosed with autism spectrum disorder (ASD). An alternating treatment design was used to compare the latency of transitions from a preferred activity to an academic task after presenting a low- or high-tech VAS. Results indicated different effects between participants. Low-tech VAS was effective for one participant, and high-tech VAS was not effective for any participants in this study. Implications and further research are discussed regarding the importance of creating VAS on an individual basis, ensuring that each VAS meets an individual's communication and …

You’Re On Fire: Social Skills Training To Increase Sportsmanship For Teenagers With Disabilities, Madeline K. Wainwright

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

This study presents findings from a multiple probe design that evaluated the effects of social skills training as a method of teaching an increase of good sportsmanship, more particularly compliments of gameplay, for individuals with intellectual disabilities. The research included three U.S. high school students with intellectual disabilities and the data was analyzed across conditions. Following mastery criterion, generalization sessions across contexts were conducted. All participants acquired complimenting behavior through social skills training. However, none of the participants were able to generalize the skill to different contexts. Results and directions for future research regarding generalization in replication and use of …

How Do Couples Of Autistic Children Perceive Their Quality Of Life? A Case Study Featuring Sequential Mixed Methodology, Amanda Duncan Dr.

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Families who have autistic children report significantly lower quality of life indicators than neurotypical families and those with other developmental disabilities (Bitsika & Sharpley, 2004; Brown et al., 2006; Charnsil & Bathia, 2010; De Sousa, 2010; Merkaj et al., 2013). However, the reports fluctuate between family members as mothers report more mental health challenges than fathers, including stress, anxiety, and depression (Dabrowska & Pstiula, 2010; Hodapp et al., 2003; Merkaj et al., 2013). Yet, these findings are based on the limited research that has been done on fathers and couples (Cheuk & Lashewicz, 2015; Osborne & Reed, 2008; Papageorgiou & …

Assessing The Content Validity And Usability Of An Implementation Fidelity Checklist For The Assessment, Evaluation, And Programming System, 3rd Edition (Aeps-3), Cameron A. Tyrrell

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The included studies examined the content validity and useability of an implementation fidelity checklist for the Assessment, Evaluation, and Programming System (AEPS) for Infants and Young Children 3^rd Edition (AEPS-3). Study 1 assessed a revised version of an implementation fidelity checklist for item clarity and criterion clarity. After further revisions, Study 2 asked administrators of early childhood educational programs to implement the fidelity checklist in a classroom environment and assess the clarity of items, criterion, and feasibility of scoring different items. In addition, administrators included the length of time it took the implement the checklist and the strengths and …

Exercise As An Antecedent Intervention, Alexis M. Estephan

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Special education classroom teachers often experience students demonstrating challenging behaviors causing themselves and their peers to fall off task. This study examined the effect of antecedent exercise on on-task behaviors. This exercise included modeling a dance video to assess increasing levels of duration of on-task behaviors.

Effectiveness Of Class-Wide Function Related Intervention Teams On The On-Task Behavior Of Middle School Students With Disabilities In A Resource Settings, Sharon Manikya

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The current study examined the effectiveness of Class-Wide Function-related Intervention Teams (CW-FIT) in promoting on-task behavior and improving classroom functioning. The study was conducted with five students, and a single-subject withdrawal experimental design was used to evaluate the impact of CW-FIT on students’ behavior. Results demonstrated a functional relation between the intervention and increased on-task behavior. Overall, findings indicated that CW-FIT had a positive effect on student behavior and classroom functioning, suggesting that the intervention is an effective strategy for enhancing engagement and promoting a productive learning environment. Implications for future research include examining CW-FIT with larger groups of students, …

Special Educator Persistence: Unveiling Teacher Perceptions, Janet Nutt

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

There is a continually growing shortage of special education teachers (SET). The shortage is so dire that the U.S. Bureau of Labor Statistics (2024) anticipates that as many as 35,900 new SET will be needed each year for the next decade. One of the leading factors contributing to the shortage of special educators is attrition, or any loss of teachers from their positions (Darling-Hammond, 2003; Ingersoll, 2001). Teacher persistence, therefore, is a critical concern in addressing the teacher shortage. The purpose of this mixed-methods research study is to examine the association between previously identified factors of attrition and SET decisions …

Evaluating A Naturalistic Language Intervention With Students With Complex Communication Needs In An Elementary Classroom, Kristina M. Johnson

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Communication is an essential skill for all students, but specifically for students with moderate to severe disabilities. Through communication, our students with disabilities express their wants and need, make and maintain relationships, and participate in daily activities at home, school, and in the community. Play is a natural and motivating activity that encourages communication in all settings. Thus, I looked at using naturalistic language intervention (NLI) as an intervention strategy to increase expressive communication skills in my students with expressive language deficits. This project aimed to increase expressive communication skills in three elementary students with moderate to severe disabilities by …

Gait Variability As A Marker Of White Matter Integrity In Individuals With Down Syndrome, Elizabeth M. Leach, David K. Powell, Amanda C. Glueck, Elizabeth Head, Moaz W. Ibrahim, Amelia J. Anderson-Mooney, Kathryn L. Van Pelt, Jordan P. Harp, Frederick A. Schmitt, Ahmed A. Bahrani

Sanders-Brown Center on Aging Faculty Publications

Introduction: Individuals with Down syndrome (DS) face a significant risk of neurodegeneration, and gait variability may serve as a clinical biomarker of neurological health. This longitudinal parent substudy aimed to explore relationships between gait, white matter (WM) integrity, and cognitive function in DS.

Methods: The associations were investigated between magnetic resonance imaging diffusion tensor imaging (DTI), cognition, and self-paced gait data from 22 DS participants (mean age ± SD 37 ± 7.5 years).

Results: DTI measures, such as lower fractional anisotropy (FA) and higher mean diffusivity, were correlated with greater step time variability but not normalized velocities. Lower cognitive scores …

Disrupted Calcium Dynamics In Reactive Astrocytes Occur With End Feet–Arteriole Decoupling In An Amyloid Mouse Model Of Alzheimer’S Disease, Blaine Weiss, John C. Gant, Ruei-Lung Lin, Jenna L. Gollihue, Colin B. Rogers, Susan D. Kraner, Edmund B. Rucker, Yuriko Katsumata, Yang Jiang, Peter T. Nelson, Donna M. Wilcock, Pradoldej Sompol, Olivier Thibault, Christopher M. Norris

Sanders-Brown Center on Aging Faculty Publications

While cerebrovascular dysfunction and reactive astrocytosis are extensively characterized hallmarks of Alzheimer's disease (AD) and related dementias, the dynamic relationship between reactive astrocytes and cerebral vessels remains poorly understood. Here, we used jGCaMP8f and two-photon microscopy to investigate calcium signaling in multiple astrocyte subcompartments, concurrent with changes in cerebral arteriole activity, in fully awake 7- to 8-month-old male and female 5xFAD mice, a model for AD-like pathology, and wild-type (WT) littermates. In the absence of movement, spontaneous calcium transients in barrel cortex occurred more frequently in astrocyte somata, processes, and perivascular regions of 5xFAD mice. However, evoked arteriole dilations (in …

Confronting The Duty To Capitalize In Veil-Piercing, Douglas C. Michael

Law Faculty Scholarly Articles

In corporate law, the doctrine of “piercing the corporate veil” allows courts to hold shareholders personally liable for corporate obligations. The doctrine—which now also applies to entities other than corporations—has been widely criticized as imprecise and unworkable. I respond to that criticism in the area of veil-piercing law which remains most intractable—the case of the tort victim who remains unsatisfied after exhausting corporate assets. Although most commentators have eschewed talk of any duty owed by the business owner to vest the business with sufficient assets, I argue that courts and legislatures should recognize—confront—such a duty. I look to negligence law …

The Migration Of Abolition Theory, Matthew Boaz

Law Faculty Scholarly Articles

This Article considers whether and how theories of abolition developed by criminal law scholars are transferrable to the realm of immigration enforcement. A key question is how abolitionist principles might be employed in support of critiques of the United States’ immigration regulatory regime in the same way that these principles have been deployed in denouncing racialized policing and an injurious, industrialized prison system.

This Article makes two contributions: First, it identifies and illuminates a methodology adopted by critical and decarceral criminal law scholars: (i) denouncing the harms of a structural system, (ii) identifying the normative justification(s) for this system, and …

Air Pollution Exposures And Cognitive Function Among Older Americans, Clarisse Nyondo Okoma

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: New findings indicate that environmental factors, such as air pollution, could contribute to cognitive decline among older adults. Nonetheless, extensive longitudinal studies in the U.S. investigating this connection are few and far between.

Objective: This study assessed the relationship between long-term exposure to ambient air pollutants and cognitive function in older adults in the United States.

Methods: We examined data from the Health and Retirement Study (2010-2018), which included 234,250 observations from adults aged 50 and older. Cognitive performance was evaluated based on immediate and delayed word recall, a 27-point cognitive summary score, backward from 20, and …

Rct Pre-Post Training Analysis Of The Vipcorps Maternal Mortality Prevention Course With A Focus On Intimate Partner Violence (Ipv), Rose A. Wood

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Maternal mortality rates rob families across the U.S. of a mother figure, and each death is preventable. The U.S. has the highest maternal mortality rate of high-earning countries. This study assesses the effects of the VIPCorps program, a course on the top 3 risk factors of maternal mortality, on improving knowledge and attitudes towards victims of IPV. Students in helping professions at the University of Kentucky (n = 223) were recruited via on campus advertising and remotely allocated to either the VIPCorps program or a mock maternal mortality training control. Generalized linear modeling was used to estimate the difference in …

Improving End-Of-Life Care: A Nursing Education Initiative, Spring C. Kingsley

DNP Projects

Background: This study addresses the gap in education and training for medical intensive care unit (MICU) nurses regarding the care of hospice patients. The traditional medical model of healthcare prioritizes illness treatment, often leading to inadequate end-of-life support and increased hospitalization during patients' final days. The rise of in-hospital hospice programs, or scatter-bed hospice models, highlights the need for nurses to enhance their skills in providing end-of-life compassionate care. The MICU at the University of Kentucky’s Chandler Hospital serves as a focal point for this initiative, given its role in caring for critically ill patients who require hospice attention.

Purpose: …

Pathogen Surveillance Of Viruses And Antimicrobial Resistance Through Wastewater Based Epidemiology, William Strike

Theses and Dissertations--Biomedical Engineering

Pandemic surveillance is a cornerstone in public health safety, as it enables identification of pathogens circulating within a community before they become widespread outbreaks. Wastewater based epidemiology has blossomed in recent years due to its success in the SARS-CoV-2 pandemic, but this form of public health surveillance has a global equity problem. A large majority of the wastewater-based surveillance work has been done in large metropolitan cities with access to advanced testing infrastructure, which poses a challenge as we consider where pandemics have historically emerged. Therefore, there is a need to identify, adapt, and develop workflows to meet the needs …

Stable Oxygen And Hydrogen Isotopic Ratios Of Precipitation And Modelling Of Precipitation Sources In Central Kentucky, Usa, 2017-2022, Ariel Gold-Mccoy

Theses and Dissertations--Civil Engineering

Our goals were to carry out analyses of a multi-year δ¹⁸O and δ²H dataset of precipitation from central Kentucky and to analyze the source of precipitation for storm events from 2017 to 2022. δ¹⁸O and δ²H were measured for 244 weekly precipitation samples collected by the National Atmospheric Deposition Program at Mackville, Kentucky, USA. Modelling precipitation source was carried out using HYSPLIT model for 414 events. Results of δ¹⁸O and δ²H from central Kentucky show: consistent seasonality, including summer highs and winter lows for δ¹⁸O and δ²H; correlation with air temperature; and …

Measuring Accessibility Of Electric Vehicle Charging Infrastructure: A Case Study In Kentucky, Oluwasola Elijah Fagbohun

Theses and Dissertations--Civil Engineering

This thesis assesses spatial accessibility to electric vehicle charging infrastructure across Kentucky by investigating methodological approaches to measure accessibility: provider-topopulation ratios, regional accessibility metrics, and several methods in the family of gravity models. The Enhanced Two-Step Floating Catchment Area method was employed to measure electric vehicle charging station accessibility across Kentucky using a network-based approach in ArcGIS Pro. The analysis integrated 2023 American Community Survey 5-year Census block group data, Kentucky road network datasets, charging station locations from the Alternative Fuels Data Center, and Alternative Fuel Corridor designations. We examined existing infrastructure and proposed stations outlined in the Kentucky electric …