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East Greenland Ice Sheet Retreat History From Scoresby Sund And Storstrømmen Glacier During The Last Deglaciation, Jacob T.H. Anderson, Nicolás E. Young, Allie Balter-Kennedy, Karlee K. Prince, Caleb K. Walcott-George, Brandon L. Graham, Joanna Charton, Jason P. Briner, Joerg M. Schaefer Nov 2025

East Greenland Ice Sheet Retreat History From Scoresby Sund And Storstrømmen Glacier During The Last Deglaciation, Jacob T.H. Anderson, Nicolás E. Young, Allie Balter-Kennedy, Karlee K. Prince, Caleb K. Walcott-George, Brandon L. Graham, Joanna Charton, Jason P. Briner, Joerg M. Schaefer

Earth and Environmental Sciences Faculty Publications

The lack of geological constraints on past ice-sheet change in marine-based sectors of the Greenland Ice Sheet (GrIS) following the Last Glacial Maximum limits our ability to assess (1) the drivers of ice-sheet change, and (2) the performance of ice-sheet models that are benchmarked against the paleo-record of GrIS change. Here, we provide new in situ10Be surface exposure chronologies of ice-sheet margin retreat from the outer Scoresby Sund and Storstrømmen Glacier regions in eastern and northeastern Greenland, respectively. Ice retreated from Rathbone Island, east of Scoresby Sund, by ∼ 14.1 ka, recording some of the earliest documentations of …


Governors Slightly More Bound? A Critique Of The Uniform Law Commission's Model Public-Health Emergency Authority Act, Paul A. Diller Nov 2025

Governors Slightly More Bound? A Critique Of The Uniform Law Commission's Model Public-Health Emergency Authority Act, Paul A. Diller

Kentucky Law Journal

No abstract provided.


Courting Jural Rights: The Kentucky Constitution And The Super Common Law Of Torts, Sarah L. Swan Nov 2025

Courting Jural Rights: The Kentucky Constitution And The Super Common Law Of Torts, Sarah L. Swan

Kentucky Law Journal

No abstract provided.


Protecting Public Employees' Free Speech: It's Time For The Sixth Circuit To Take Action, Faith O. Turner Nov 2025

Protecting Public Employees' Free Speech: It's Time For The Sixth Circuit To Take Action, Faith O. Turner

Kentucky Law Journal

No abstract provided.


The End Of An Aberration: Overturning Major League Baseball's Century-Old Antitrust Exemption, Jacob Baird Nov 2025

The End Of An Aberration: Overturning Major League Baseball's Century-Old Antitrust Exemption, Jacob Baird

Kentucky Law Journal

No abstract provided.


Fighting Death: A Critique Of Kentucky's Death Penalty System, Pamela R. Goodwine Nov 2025

Fighting Death: A Critique Of Kentucky's Death Penalty System, Pamela R. Goodwine

Kentucky Law Journal

No abstract provided.


Ductile Rights, W. C. Bunting Nov 2025

Ductile Rights, W. C. Bunting

Kentucky Law Journal

No abstract provided.


For One Or For All: Who Gets The Benefits Of The First Step Act?, Andrew Edwards Nov 2025

For One Or For All: Who Gets The Benefits Of The First Step Act?, Andrew Edwards

Kentucky Law Journal

No abstract provided.


The Major Question Left For The Roberts Court, Will Chevron Survive?, Caleb B. Childers Nov 2025

The Major Question Left For The Roberts Court, Will Chevron Survive?, Caleb B. Childers

Kentucky Law Journal

No abstract provided.


Against Algorithmic Auer Deference, Chad Squitieri Nov 2025

Against Algorithmic Auer Deference, Chad Squitieri

Kentucky Law Journal

No abstract provided.


How Standards Of Review Under Erisa Impair Mental Health Parity: An Analysis Of Wit V. United Behavioral Health, Hayden K. Hickey Nov 2025

How Standards Of Review Under Erisa Impair Mental Health Parity: An Analysis Of Wit V. United Behavioral Health, Hayden K. Hickey

Kentucky Law Journal

No abstract provided.


The Paradox Of Barring Early-Release Defendants From Section 1983 Relief, Emily M. Puckett Nov 2025

The Paradox Of Barring Early-Release Defendants From Section 1983 Relief, Emily M. Puckett

Kentucky Law Journal

No abstract provided.


Scotus's Summer Of 2022: Obfuscation Of And Disdain For Rationality And The Traditional Personal Liberties Framework, Roy G. Spece Jr. Nov 2025

Scotus's Summer Of 2022: Obfuscation Of And Disdain For Rationality And The Traditional Personal Liberties Framework, Roy G. Spece Jr.

Kentucky Law Journal

No abstract provided.


The Law Fox Manifesto, Benjamin H. Barton Nov 2025

The Law Fox Manifesto, Benjamin H. Barton

Kentucky Law Journal

No abstract provided.


The Right To Record Police Must Be Clearly Established, Cole S. Manion Nov 2025

The Right To Record Police Must Be Clearly Established, Cole S. Manion

Kentucky Law Journal

No abstract provided.


The Phantasm Of Principle, Wilfred U. Codrington Iii Nov 2025

The Phantasm Of Principle, Wilfred U. Codrington Iii

Kentucky Law Journal

No abstract provided.


Apoe-Targeted Therapeutics For Alzheimer’S Disease, Hussein N. Yassine, Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory Cole, Julia Tcw, Jan Johansson, Kassandra Kisler, Ornit Chiba-Falek Nov 2025

Apoe-Targeted Therapeutics For Alzheimer’S Disease, Hussein N. Yassine, Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory Cole, Julia Tcw, Jan Johansson, Kassandra Kisler, Ornit Chiba-Falek

Physiology Faculty Publications

Apolipoprotein E (APOE) is the major lipid transport protein in the brain. Produced primarily by astrocytes and microglia, it delivers cholesterol and other lipids for membrane repair, synaptic maintenance, and immune regulation. Through interactions with specific lipid receptors, APOE maintains neuronal and vascular health. The APOE ε4 allele (APOE4), carried by approximately one-quarter of the population, has an altered protein conformation, which reduces lipid transport efficiency and modifies receptor binding. These changes disrupt lipid homeostasis, increase risk of chronic unresolved neuroinflammation and vascular inflammation, and cause breakdown of the blood–brain barrier (BBB), thus increasing neuronal vulnerability to disease pathology and …


Predicting An Uncertain Future: Conservation Easements And The Difficulties Created By Speculative Valuations, Travis L. Strickler Nov 2025

Predicting An Uncertain Future: Conservation Easements And The Difficulties Created By Speculative Valuations, Travis L. Strickler

Kentucky Law Journal

No abstract provided.


The Cost Of Our Constitutional Rights: An Examination Of Prison Medical Treatment For Hepatitis-C, M. Abigail Schueler Nov 2025

The Cost Of Our Constitutional Rights: An Examination Of Prison Medical Treatment For Hepatitis-C, M. Abigail Schueler

Kentucky Law Journal

No abstract provided.


The Interpretive Foundations Of Arbitrary Or Capricious Review, Alexander Mechanick Nov 2025

The Interpretive Foundations Of Arbitrary Or Capricious Review, Alexander Mechanick

Kentucky Law Journal

No abstract provided.


Crony Stakeholder Capitalism, Stefan J. Padfield Nov 2025

Crony Stakeholder Capitalism, Stefan J. Padfield

Kentucky Law Journal

No abstract provided.


Age Is More Than Just A Number: A Legal And Ethical Defense Of Age-Based Triage Protocols, Jessica Mantel Nov 2025

Age Is More Than Just A Number: A Legal And Ethical Defense Of Age-Based Triage Protocols, Jessica Mantel

Kentucky Law Journal

No abstract provided.


Equality Can Stick With Bostock: A Call To Expand The Equal Protection Clause To Include Discrimination Against Transgender People's Bathroom Usage, Jackson B. Hurst-Sanders Nov 2025

Equality Can Stick With Bostock: A Call To Expand The Equal Protection Clause To Include Discrimination Against Transgender People's Bathroom Usage, Jackson B. Hurst-Sanders

Kentucky Law Journal

No abstract provided.


Art, Antiquities, And Money Laundering, Derek Fincham Nov 2025

Art, Antiquities, And Money Laundering, Derek Fincham

Kentucky Law Journal

No abstract provided.


Distilling The Language Of The Law, Stacey A. Tovino Nov 2025

Distilling The Language Of The Law, Stacey A. Tovino

Kentucky Law Journal

No abstract provided.


Fifty More Years Of Ineffable Quo? Workers' Compensation And The Right To Personal Security, Michael C. Duff Nov 2025

Fifty More Years Of Ineffable Quo? Workers' Compensation And The Right To Personal Security, Michael C. Duff

Kentucky Law Journal

No abstract provided.


The Most Dangerous Of All Subversions: Taming The At-Will Employment Doctrine By Statutorily Safeguarding Private Employees' Public Protest Speech, Joshua G. Wolford Nov 2025

The Most Dangerous Of All Subversions: Taming The At-Will Employment Doctrine By Statutorily Safeguarding Private Employees' Public Protest Speech, Joshua G. Wolford

Kentucky Law Journal

No abstract provided.


Freed From Prison And Unemployed: What Happens After Your Prison Job Ends?, Stephanie Hunter Mcmahon Nov 2025

Freed From Prison And Unemployed: What Happens After Your Prison Job Ends?, Stephanie Hunter Mcmahon

Kentucky Law Journal

No abstract provided.


Interest Convergence And The Racial Wealth Gap: Defusing Racism's Divide-And-Conquer Via Universal Basic Income, Palma Joy Strand, Nicholas A. Mirkay Nov 2025

Interest Convergence And The Racial Wealth Gap: Defusing Racism's Divide-And-Conquer Via Universal Basic Income, Palma Joy Strand, Nicholas A. Mirkay

Kentucky Law Journal

No abstract provided.


Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Tate Nov 2025

Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Tate

Kentucky Law Journal

No abstract provided.