Digital Commons Network^™

Measurement Of Sequential ϒ Suppression In Au + Au Collisions At √Snn = 200 Gev With The Star Experiment, Star Collaboration

Physics and Astronomy Faculty Publications

We report on measurements of sequential ϒ suppression in Au+Au collisions at sNN=200 GeV with the STAR detector at the Relativistic Heavy Ion Collider (RHIC) through both the dielectron and dimuon decay channels. In the 0%-60% centrality class, the nuclear modification factors (RAA), which quantify the level of yield suppression in heavy-ion collisions compared to p+p collisions, for ϒ(1S) and ϒ(2S) are 0.40±0.03(stat)±0.03(sys)±0.09(norm) and 0.26±0.08(stat)±0.02(sys)±0.06(norm), respectively, while the upper limit of the ϒ(3S) RAA is 0.17 at a 95% confidence level. This provides experimental evidence that the ϒ(3S) is significantly more suppressed than the ϒ(1S) at RHIC. The level of …

Measurementus Magnetic Moment To 0.20 Ppm Of The Positive Muon Anomalo, The Muon G − 2 Collaboration

Physics and Astronomy Faculty Publications

We present a new measurement of the positive muon magnetic anomaly, aμ(gμ-2)/2, from the Fermilab Muon g-2 Experiment using data collected in 2019 and 2020. We have analyzed more than 4 times the number of positrons from muon decay than in our previous result from 2018 data. The systematic error is reduced by more than a factor of 2 due to better running conditions, a more stable beam, and improved knowledge of the magnetic field weighted by the muon distribution, p′, and of the anomalous precession frequency corrected for beam dynamics effects, ωa. From the ratio ωa/p′, together with precisely …

Manipulation Of Components Of The Renin Angiotensin System In Renal Proximal Tubules Fails To Alter Atherosclerosis In Hypercholesterolemic Mice, Masayoshi Kukida, Naofumi Amioka, Dien Ye, Hui Chen, Jessica J. Moorleghen, Ching-Ling Liang, Deborah A. Howatt, Yuriko Katsumata, Motoko Yanagita, Hisashi Sawada, Alan Daugherty, Hong S. Lu

Saha Cardiovascular Research Center Faculty Publications

Background and objective: Whole body manipulation of the renin-angiotensin system (RAS) consistently exerts profound effects on experimental atherosclerosis development. A deficit in the literature has been a lack of attention to the effects of sex. Also, based on data with gene-deleted mice, the site of RAS activity that influences lesion formation is at an unknown distant location. Since angiotensin (AngII) concentrations are high in kidney and the major components of the RAS are present in renal proximal tubule cells (PTCs), this study evaluated the role of the RAS in PTCs in atherosclerosis development.

Methods and results: Mice with an LDL …

Organizational Access Points And Substance Use Disorder Treatment Utilization Among Black Women: A Longitudinal Cohort Study, Sugy Choi, Amanda Bunting, Talia Nadel, Charles J. Neighbors, Carrie B. Oser

Sociology Faculty Publications

Introduction Health and social service organizations, including the emergency department (ED) and public assistance programs, constitute a social safety net that may serve as an “access point” for substance use treatment utilization. Racialization of substance use disorder (SUD) and gender disparities in access to treatment contribute to differences in health and social service utilization, including substance use treatment for Black women. We therefore explored the role of various access points in facilitating the use of substance use treatment among Black women with substance use and involvement in the criminal justice system.

Methods We used data from the Black Women in …

Southeastern Law Librarian 2023 Special Election Edition, Seaall

Newsletters

No abstract provided.

Southeastern Law Librarian Winter 2023, Seaall

Newsletters

No abstract provided.

Bolstering Resistance To Misinformation Through K-12 Education, Allison Johnson

Undergraduate Public Policy Capstone Projects

Misinformation online and in news media is a problem because it degrades truth and hinders legitimate democratic discourse. As misinformation becomes more prevalent, we need to start finding ways to limit the extent of the problem. To do so, I recommend a policy solution based on inoculation theory. Inoculation theory, as the name suggests, uses the metaphor of a vaccine. When receiving the flu shot, we get a weakened dose of the virus, which in turn helps us to create antibodies and later be more effective at fighting the real flu. In this instance, people are exposed to weakened doses …

Macrophage Polarization Status Impacts Nanoceria Cellular Distribution But Not Its Biotransformation Or Ferritin Effects, Uschi M. Graham, Alan K. Dozier, David James Feola, Michael T. Tseng, Robert Yokel

Nanobiotechnology Center Faculty Publications

The innate immune system is the first line of defense against external threats through the initiation and regulation of inflammation. Macrophage differentiation into functional pheno- types influences the fate of nanomaterials taken up by these immune cells. High-resolution electron microscopy was used to investigate the uptake, distribution, and biotransformation of nanoceria in human and murine M1 and M2 macrophages in unprecedented detail. We found that M1 and M2 macrophages internalize nanoceria differently. M1-type macrophages predominantly sequester nanoceria near the plasma membrane, whereas nanoceria are more uniformly distributed throughout M2 macrophage cytoplasm. In contrast, both macrophage phenotypes show identical nanoceria biotransformation …

Race Conscious Affirmative Action By Tax Exempt 501(C)(3) Institutions After Students For Fair Admissions V. Harvard And Unc, David A. Brennen

Law Faculty Scholarly Articles

In 1983, several years after its 1954 decision in Brown v. Board of Education, the United States Supreme Court decided a case that significantly impacted tax-exempt § 501(c)(3) charitable schools that consider race in making admissions decisions. In Bob Jones University v. United States, the Court held that a private school that discriminates against African Americans in admissions is not entitled to § 501(c)(3) tax-exempt status. The Court based its decision on the public policy doctrine, an off-shoot of the well established illegality doctrine. Pursuant to the public policy doctrine, the Court upheld the IRS’s decision to deny …

Making Sense Of “Commence” In The Clean Water Act’S Diligent Prosecution Bar, Isa Harrison

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

A New Rule: Why Broad Jurisdiction Under § 404 Of The Clean Water Act Will Protect Wetlands, Gracie Sandlin

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Companies Over Countries: A More Pointed Approach To International Climate Treaties, Alex G. Woodward

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Surficial Geologic Map Of The Rockfield 7.5-Minute Quadrangle, Warren, Logan, And Simpson Counties, Kentucky, Wes Buchanan, Meredith Swallom, Antonia Bottoms, Matthew Massey, Bailee Nicole Hodelka, Emily Morris

Contract Reports--KGS

The Rockfield 7.5-minute quadrangle is located west of Bowling Green, Kentucky situated mostly in Warren County, but also includes small areas of Simpson and Logan Counties in its southwestern corner. Regionally, the quadrangle includes parts of the Pennyroyal and Mammoth Cave plateau within the Mississippian Plateaus physiographic region (McDowell, 1986). The Dripping Springs escarpment, which separates the lower-elevation Pennyroyal from the higher-elevation Mammoth Cave plateau is highly dissected in the quadrangle. Topography in the Pennyroyal is characterized by pervasive sinkhole development across a low-relief plain, which is mostly underlain by the Mississippian Ste. Genevieve Limestone. Higher-relief topography is restricted to …

Surficial Geologic Map Of The Hadley 7.5-Minute Quadrangle, Warren County, Kentucky, Matthew Massey, Meredith Swallom, Antonia Bottoms, Wes Buchanan, Bailee Nicole Hodelka, Emily Morris

Contract Reports--KGS

The Hadley 7.5-minute quadrangle is located in Warren County northwest of Bowling Green, Kentucky. Regionally, the quadrangle is entirely within the Mammoth Cave plateau, which is located in the Mississippian Plateaus physiographic region (McDowell, 1986). The Mammoth Cave plateau is a regional west-dipping cuesta, that has been extensively incised by the Green and Barren Rivers and their tributaries. The area is underlain by Upper Mississippian to Lower Pennsylvanian (Rainey, 1963): the lowest fluvial valleys are underlain by Ste. Genevieve Limestone; Girkin Formation is exposed on the steep slopes between the lower valleys and higher plateau; the plateau is underlain by …

Surficial Geologic Map Of The Bowling Green North 7.5-Minute Quadrangle, Warren County, Kentucky, Meredith Swallom, Matthew Massey, Wes Buchanan, Bailee Nicole Hodelka, Hannah Hayes, Charles Wells Iii, Emily Morris

Contract Reports--KGS

The Bowling Green North 7.5-minute quadrangle is located in Warren County immediately north of Bowling Green, Kentucky. Regionally, the quadrangle includes parts of the Pennyroyal and Mammoth Cave plateau, both within the Mississippian Plateaus physiographic region (McDowell, 1986). The Dripping Springs escarpment, which separates the lower-elevation Pennyroyal from the higher-elevation Mammoth Cave plateau is highly dissected in the quadrangle. Topography in the Pennyroyal is characterized by pervasive sinkhole development across the low-relief Pennyroyal, which is mostly underlain by the Mississippian St. Louis Limestone, Ste. Genevieve Limestone, and Girkin Formation (Shawe, 1963). Higher-relief topography is restricted to the slopes of the …

Artificial Intelligence And The Practice Of Law Part 1: Lawyers Must Be Professional And Responsible Supervisors Of Ai, Michael D. Murray

Law Faculty Popular Media

No abstract provided.

Persuasion Through Citation: Four Ways To Enhance Your Legal Arguments With Proper Legal Citation, Melissa N. Henke

Law Faculty Popular Media

No abstract provided.

Development And Biological Evaluation Of Selective Small-Molecule Inhibitors Of The Human Cytochrome P450 1b1, Austin Hachey

Theses and Dissertations--Chemistry

The human cytochrome P450 1B1 (CYP1B1) is an emerging target for small- molecule therapeutics. Several solid tumors overexpress CYP1B1 to the degree that it has been referred to as a universal tumor antigen. Conversely, its expression is low in healthy tissues. CYP1B1 may drive tumorigenesis through promoting the formation of reactive toxins from environmental pollutants or from endogenous hormone substrates. Additionally, the expression of CYP1B1 in tumors is associated with resistance to several common chemotherapies and with poor prognoses in cancer patients. However, inhibiting CYP1B1 with small molecules has been demonstrated in cellular and murine model systems to reverse this …

Paper Gowns, Cold Hands, Or Something Else? Black Women's Barriers To Gynecologic Screening, Nadia Ayesha Sesay

Theses and Dissertations--Communication

Cervical cancer mortality burden is carried disproportionately by African American women. Early indicators of cervical cancer are identified through prevention screening, a procedure typically performed by a gynecologist. Ideally, the patient group with the most severe mortality would likewise be the group with the most robust communication exchange with their physician to prevent cervical cancer incidence. However, a slew of factors contributes to continued mortalities among Black women. This study uses semi-structured interviews (n=10) and the health belief model to examine one barrier to Black women’s prosocial behaviors regarding routine gynecologic care—awkwardness, which here is conceptualized as social anxiety. The …

Cold Calling In The Classroom: Exploring Student Perceptions Of Instructor Communication Using The Face Negotiation Theory, Cynthia Chinazo Nnagboro

Theses and Dissertations--Communication

Using face negotiation theory (Ting-Toomey, 1988) as a theoretical framework, this dissertation sought to determine students’ perceptions of instructor communication during classroom discussions where instructors use cold calling tactics. According to FNT, students perceived that self-construal determines their face concern as either self, other/mutual face. Therefore, an instructor must determine the best facework strategies to prevent face loss during classroom discussions to maintain optimal student outcomes in communication satisfaction and motivation to participate. This was accomplished by using 8 hypothetical vignettes, a pilot test and an experiment that measured face threat, face support, student communication satisfaction and motivation, intention to …

Identity And Perception Among Aspec Consumers Of Mass Media, Jericho Franke

Theses and Dissertations--Communication

The portrayals of sex and romance, as well as asexuality and aromanticism, in mass media can have a profound impact on the way asexual and aromantic media consumers view relationships and their own identities, and affect the perception and treatment of the aspec community as a whole. This study uses mixed qualitative methods of online discourse analysis and participant interviews to examine the how mass media has shaped the self-perception and life experiences relating to sex and romance among aspec audience members.

Hmgb2 Regulates The Differentiation And Stemness Of Exhausted Cd8+ T Cells During Chronic Viral Infection And Cancer, Emily N. Neubert, Julia M. Derogatis, Sloan A. Lewis, Karla M. Viramontes, Pedro Ortega, Monique L. Henriquez, Rémi Buisson, Ilhem Messaoudi, Roberto Tinoco

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Chronic infections and cancers evade the host immune system through mechanisms that induce T cell exhaustion. The heterogeneity within the exhausted CD8⁺ T cell pool has revealed the importance of stem-like progenitor (Tpex) and terminal (Tex) exhausted T cells, although the mechanisms underlying their development are not fully known. Here we report High Mobility Group Box 2 (HMGB2) protein expression is upregulated and sustained in exhausted CD8⁺ T cells, and HMGB2 expression is critical for their differentiation. Through epigenetic and transcriptional programming, we identify HMGB2 as a cell-intrinsic regulator of the differentiation and maintenance of Tpex cells during …

Enabling Dapps Data Exchange With Hardware-Assisted Secure Oracle Network, Yue Li

Theses and Dissertations--Computer Science

Decentralized applications (dApps), enabled by the blockchain and smart contract technology, are known for allowing distrustful parties to execute business logic without relying on a central authority. Compared to regular applications, dApps offer a wide range of benefits, including security by design, trustless transactions, and resistance to censorship. However, dApps need to access real-world data to achieve their full potential, relying on the data oracles. Oracles act as bridges between blockchains and the outside world, providing essential data to the smart contracts that power dApps. A significant challenge in integrating oracles into the dApp ecosystem is the Oracle Problem …

Using 3-Dimensional Mapping To Determine The Possibility Of Structural Control On Development Of The Upper Ordovician Lexington Limestone, Central Kentucky, U.S.A., Sean Davis

Theses and Dissertations--Earth and Environmental Sciences

The upper Lexington Limestone of Late Ordovician age has been interpreted to represent a structurally controlled, complex, facies mosaic. This facies mosaic has historically been interpreted to be a carbonate buildup of shoal complexes with interbedded shale units with intertonguing facies. Due to relatively recent advances in geographic-information-systems (GIS) mapping technologies, it is possible to generate three-dimensional (3-D) compatible maps to offer insight to the complexities of the upper Lexington Limestone and to determine if structural control affected the distribution of members. The resulting two-dimensional (2-D) and 3-D maps show that basement faults likely exerted a significant influence on facies …

Evaluation Of Increasing Levels Of Mycotoxin-Containing Corn Fines On Diet Choice And Growth Performance Of Nursery Pigs, Duncan B. Paczosa

Theses and Dissertations--Animal and Food Sciences

Pigs fed mycotoxin contaminated diets at high concentrations will result in a detriment to health and performance. An initial study and a follow-up study were conducted to evaluate the effects of feeding increasing levels of mycotoxin-containing corn fines on growth performance, diet preference of pigs, and two possible mitigants.

The initial study was a 3 x 2 factorial containing three levels of fines (0, 10, and 20%, Diets 1-3, respectively) and either 0 ppm (Diets 1-3) or 40 ppm boron (Diets 4-6; Diets 4-6 were Diets 1-3, respectively, plus boron) as sodium tetraborate decahydrate as a possible mitigant. In this …

Profiling The Cell Wall Polysaccharides Of Hemp (Cannabis Sativa L.) Inflorescence And Hempseed And Exploring Their Application As Ruminant Feed Ingredients, Miranda Agbana

Theses and Dissertations--Animal and Food Sciences

Hemp (Cannabis sativa L.) is used in the United States as a source of CBD oil, fiber, and grain. While hempseeds are consumed whole or as dehulled hemp hearts, hempseed oil is also a desirable seed oil in human nutrition. The process of collecting hempseed oil leaves behind hempseed cakes that are abundant in protein and fiber. Feeding of hempseed cakes to animals, including ruminants, has only initially been explored. Extraction of CBD from hemp inflorescences generates organic waste that may find a second purpose as a fiber feed for cattle. Little is known about the exact fiber composition …

Beam Dynamics Simulations And Systematic Studies For The Muon G-2 Experiment At Fermilab, Abel M. Lorente Campos

Theses and Dissertations--Physics and Astronomy

The first results of the positive muon anomalous magnetic moment from the Muon g-2 Experiment at Fermilab differs from the Standard Model prediction by 3.3 standard deviations, with an experimental uncertainty of 0.46 ppm. Combining this result with the previous measurement from the Brookhaven National Laboratory, it sets the difference between experiment and theory at 4.2 standard deviations. The goal of the Muon g-2 Experiment at Fermilab is to increase this discrepancy to 5 standard deviations, which would require unprecedented precision in the measurements of 0.14 ppm. Of significant importance to achieving this precision, beam and spin dynamics simulations are …

Mild/Asymptomatic Covid-19 In Unvaccinated Pregnant Mothers Impairs Neonatal Immune Responses, Brianna M. Doratt, Suhas Sureshchandra, Heather E. True, Monica Rincon, Nicole E. Marshall, Ilhem Messaoudi

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Maternal SARS-CoV-2 infection triggers placental inflammation and alters cord blood immune cell composition. However, most studies focus on outcomes of severe maternal infection. Therefore, we analyzed cord blood and chorionic villi from newborns of unvaccinated mothers who experienced mild/asymptomatic SARS-CoV-2 infection during pregnancy. We investigated immune cell rewiring using flow cytometry, single-cell RNA sequencing, and functional readouts using ex vivo stimulation with TLR agonists and pathogens. Maternal infection was associated with increased frequency of memory T and B cells and nonclassical monocytes in cord blood. Ex vivo T and B cell responses to stimulation were attenuated, suggesting a tolerogenic state. …

A Multilevel Jurisdictional Analysis Of The Impact Of Walmart On Host Communities, Matt Young

Theses and Dissertations--Public Policy and Administration

This research takes a holistic approach to answer the empirical question about what impacts Walmart has on host jurisdictions. This consists of a thorough review of the extant literature; a formalization of Walmart’s potential impact into a theoretical framework; a consideration of endogeneity within Walmart’s operations from multiple angles; a nationwide analysis of impacts on labor and retail markets at both the county and municipal level; a nationwide analysis of the impacts on housing prices and property tax revenue post Walmart; a multistate analysis of host jurisdictions’ reactions to these changes through the lens of local sales taxes; finally, a …

Three Essays On Consumption Taxation In Indonesia, Partomuan Transparenter Juniult

Theses and Dissertations--Public Policy and Administration

Consumption taxes play a major role in revenue generation for many developing countries. They are also used to encourage or discourage certain consumption behaviors. However, the administrative aspects of implementing these taxes can create challenges for the tax authorities, and lead to distortions in taxpayer behavior. To overcome these challenges, efforts have been made to simplify policies and utilize technology to improve administration and compliance. My dissertation aims to provide empirical evidence on the effects of three consumption or commodity tax policy reforms in Indonesia. The dissertation consists of three essays as follows.

In my first essay, titled “The effect …