Digital Commons Network^™

Optimizing Critical Illness Recovery: Perspectives And Solutions From The Caregivers Of Icu Survivors, Carla M. Sevin, Leanne M. Boehm, Elizabeth Hibbert, Anthony J. Bastin, James C. Jackson, Joel Meyer, Tara Quasim, Rita N. Bakhru, Ashley A. Montgomery-Yates, Andrew Slack, Mary Still, Giora Netzer, Mark E. Mikkelsen, Theodore J. Iwashyna, Kimberly J. Haines, Joanne Mcpeake

Internal Medicine Faculty Publications

Objectives:
To understand the unmet needs of caregivers of ICU survivors, how they accessed support post ICU, and the key components of beneficial ICU recovery support systems as identified from a caregiver perspective.

Design:
International, qualitative study.

Subjects:
We conducted 20 semistructured interviews with a diverse group of caregivers in the United States, the United Kingdom, and Australia, 11 of whom had interacted with an ICU recovery program.

Setting:
Seven hospitals in the United States, United Kingdom, and Australia.

Interventions:
None.

Measurements and Main Results:
Content analysis was used to explore prevalent themes related to unmet needs, as well as …

Undoing The Traditions Of Grading And Reporting, Thomas R. Guskey

Educational, School, and Counseling Psychology Faculty Publications

One silver lining from the ongoing public health crisis might be the lasting impact of two modified approaches to grading and reporting of the past year.

Project Management Research Support, Bryan Gibson, Jeff Jasper, Robin Baskette, Christopher Van Dyke, Doug Kreis

Kentucky Transportation Center Research Report

Like many state transportation agencies, the Kentucky Transportation Cabinet (KYTC) faces unprecedented challenges related to project development and management. Staff losses due to attrition and retirements have resulted in the loss of institutional knowledge. Early- to mid-career project managers (PMs) shoulder more responsibilities than ever while being expected to deliver over 600 successful projects each year. To improve the efficiency of project management, PMs must be able to access effective project management concepts, tools, and strategies which are field validated. Recognizing the importance of strengthening its project management capabilities, the Cabinet asked the Kentucky Transportation Center (KTC) to provide ongoing …

Application Of Eh-Ph Diagrams On Acid Leaching Systems For The Recovery Of Rees From Bastnaesite, Monazite And Xenotime, Peijia Lin, Xinbo Yang, Joshua M. Werner, Rick Q. Honaker

Mining Engineering Faculty Publications

Bastnaesite, monazite and xenotime are rare earth minerals (REMs) that are typical sources for rare earth elements (REEs). To advance the understanding of their leaching and precipitation behavior in different hydrometallurgical processes, Eh-pH diagrams were constructed and modified using the HSC 9.9 software. The aqueous stability of rare earth elements in H₂O and acid leaching systems, i.e., the REE-Ligands-H₂O systems, were depicted and studied based on the Eh-pH diagrams. This study considers the most relevant lixiviants, their resulting equilibrium states and the importance in the hydrometallurgical recovery of rare earth elements (REMs). A literature review was …

The Tacit Knowledge Dilemma In Open Science, C. Sean Burns

Information Science Presentations

A talk about the role that knowledge management (and sub areas) might play in open science. The open science movement has the goal of making transparent as much of the scientific process as is possible. This entails making publicly available (open source, access, etc.) the parts of the scientific workflow, such as the data, the software code, the manuscripts, that are used or generated in the process of doing research. However, Michael Polanyi's theory of tacit knowledge raises a dilemma that knowledge management researchers might be able to address. Specifically, if we accept the theory of tacit knowledge, the idea …

Evaluation Of Glutaminase Expression In Prostate Adenocarcinoma And Correlation With Clinicopathologic Parameters, Zin W. Myint, Ramon C. Sun, Patrick J. Hensley, Andrew C. James, Peng Wang, Stephen E. Strup, Robert J. Mcdonald, Donglin Yan, William H. St. Clair, Derek B. Allison

Internal Medicine Faculty Publications

High Glutaminase (GLS1) expression may have prognostic implications in colorectal and breast cancers; however, high quality data for expression in prostate cancer (PCa) are lacking. The purpose of this study is to investigate the status of GLS1 expression in PCa and correlated expression levels with clinicopathologic parameters. This study was conducted in two phases: an exploratory cohort analyzing RNA-Seq data for GLS1 from The Cancer Genome Atlas (TCGA) data portal (246 PCa samples) and a GLS1 immunohistochemical protein expression cohort utilizing a tissue microarray (TMA) (154 PCa samples; 41 benign samples) for correlation with clinicopathologic parameters. In the TCGA cohort, …

The Economics And Ethics Of Land Reform: A Critique Of The Pontifical Council For Justice And Peace's "Toward A Better Distribution Of Land: The Challenge Of Agrarian Reform", Walter Block, Guillermo Yeatts

Journal of Natural Resources & Environmental Law

No abstract provided.

Bone Quality In Chronic Kidney Disease Patients: Current Concepts And Future Directions – Part Ii, Kamyar Asadipooya, Mohamed Abdalbary, Yahya Ahmad, Elijah Kakani, Marie-Claude Monier-Faugere, Amr El-Husseini

Internal Medicine Faculty Publications

Background: Patients with chronic kidney disease (CKD) have an increased risk of osteoporotic fractures, which is due not only to low bone volume and mass but also poor microarchitecture and tissue quality. The pharmacological and nonpharmacological interventions detailed, herein, are potential approaches to improve bone health in CKD patients. Various medications build up bone mass but also affect bone tissue quality. Antiresorptive therapies strikingly reduce bone turnover; however, they can impair bone mineralization and negatively affect the ability to repair bone microdamage and cause an increase in bone brittleness. On the other hand, some osteoporosis therapies may cause a redistribution …

The Public’S Perceptions Of Government Officials’ Communication In The Wake Of The Covid-19 Pandemic, Shaniece B. Bickham, Diane B. Francis

Communication Faculty Publications

Early news coverage in the US about the COVID-19 pandemic focused on information released from local, state and federal government officials. With an emphasis on US government at these levels, this study examined whether the public’s credibility perceptions and trust in government, along with message exposure, influenced their adherence to information from the government about (a) stay-at-home orders, (b) social distancing and (c) COVID-19 testing. Source credibility theory and situational crisis communication theory provided the theoretical framework for this study. Through the survey data analysis, we investigated communication preferences in the wake of the pandemic and whether credibility perceptions differed …

Scaffolding High-Impact Practices For Asian Studies And The Environment, Brett Werner, Kyle Anderson, Matthew Klooster, Daniel Kirchner, Aaron Godlaski

Lewis Honors College Faculty Publications

Support from the Henry Luce Foundation allowed a team of Centre College faculty to develop multiple integrated programs connecting the study of Asia to the environment: the Centre Summer Language Institute (CSLI), the Asia & the Environment Lab (A&E Lab), January term courses abroad, student summer research and internships abroad, and student dissemination of research. Each of these high-impact practices (HIPs) alone has been empirically demonstrated to enrich student experiences, but when linked in succession through a scaffolded framework, student learning was synergistically magnified. The personal growth, academic interests, and career trajectory of students who completed all stages of the …

Suppressing Bias Stress Degradation In High Performance Solution Processed Organic Transistors Operating In Air, Hamna F. Iqbal, Qianxiang Ai, Karl J. Thorley, Hu Chen, Iain Mcculloch, Chad Risko, John E. Anthony, Oana D. Jurchescu

Chemistry Faculty Publications

Solution processed organic field effect transistors can become ubiquitous in flexible optoelectronics. While progress in material and device design has been astonishing, low environmental and operational stabilities remain longstanding problems obstructing their immediate deployment in real world applications. Here, we introduce a strategy to identify the most probable and severe degradation pathways in organic transistors and then implement a method to eliminate the main sources of instabilities. Real time monitoring of the energetic distribution and transformation of electronic trap states during device operation, in conjunction with simulations, revealed the nature of traps responsible for performance degradation. With this information, we …

An Ensemble Of The Icluster Method To Analyze Longitudinal Lncrna Expression Data For Psoriasis Patients, Suyan Tian, Chi Wang

Internal Medicine Faculty Publications

BACKGROUND: Psoriasis is an immune-mediated, inflammatory disorder of the skin with chronic inflammation and hyper-proliferation of the epidermis. Since psoriasis has genetic components and the diseased tissue of psoriasis is very easily accessible, it is natural to use high-throughput technologies to characterize psoriasis and thus seek targeted therapies. Transcriptional profiles change correspondingly after an intervention. Unlike cross-sectional gene expression data, longitudinal gene expression data can capture the dynamic changes and thus facilitate causal inference.

METHODS: Using the iCluster method as a building block, an ensemble method was proposed and applied to a longitudinal gene expression dataset for psoriasis, with the …

Improvisation As A Teaching Tool For Improving Oral Communication Skills In Premedical And Pre-Biomedical Graduate Students, Marianne Phelps, Catrina White, Lin Xiang, Hollie I. Swanson

Theatre and Dance Faculty Publications

Objective:

To evaluate the relationship between training in theatre improvisation and empathy, communication, and other professional skills.

Methods:

Undergraduate and graduate students who were participants of a 10-week summer undergraduate research program engaged in theatre improvisation techniques during a 3-hour workshop. In Study #1, a de-identified, self-report questionnaire (known as the Empathy Quotient) was administered prior to and following the workshop. Paired sample 2-tailed t-tests were performed to evaluate pre- and post-test scores. To identify additional benefits of engaging in theatre improvisation techniques, Study #2 was performed. Here, a survey was administered to the participants following their completion of …

Artists' Genres: A Brief Introduction To Post-Medieval Western Art, Robert Jensen

Art and Visual Studies Faculty Book Gallery

Artists' Genres is a brief introduction to the history of post-medieval Western art organized by the major genres. The book is designed as a basic textbook for high school- or introductory college-level courses or for individuals simply looking for an interesting guidebook into the art of this period and geographical region.

This is the revised edition of Artists' Genres: A Brief Introduction to Post-Medieval Western Art, which was released in 2018.

Case Report: The Complexities Of Managing Medications And The Importance Of Deprescribing Anticholinergics In Older Adults, Taylor Elliott, Lynne Eckmann, Daniela C. Moga

Pharmacy Practice and Science Faculty Publications

Potentially inappropriate anticholinergic medications (including over-the-counter products), polypharmacy, and the existence of communication barriers among members of the interprofessional team frequently contribute to clinical complexity in older adults. We present the case of a frail 86-year old female from the perspective of a community pharmacist managing outpatient medications and transitions of care. CD’s past medical history is significant for dementia, multiple falls, recurrent urinary tract infections, depression, cardiac arrhythmia, macular degeneration, chronic pain, depression, and cerebrovascular disease.

Gait And Balance Changes With Investigational Peripheral Nerve Cell Therapy During Deep Brain Stimulation In People With Parkinson’S Disease, Geetanjali Gera, Zain Guduru, Tritia R. Yamasaki, Julie A. Gurwell, Monica Chau, Anna Krotinger, Frederick A. Schmitt, John T. Slevin, Greg A. Gerhardt, Craig G. Van Horne, Jorge E. Quintero

Physical Therapy Faculty Publications

Background: The efficacy of deep brain stimulation (DBS) and dopaminergic therapy is known to decrease over time. Hence, a new investigational approach combines implanting autologous injury-activated peripheral nerve grafts (APNG) at the time of bilateral DBS surgery to the globus pallidus interna. Objectives: In a study where APNG was unilaterally implanted into the substantia nigra, we explored the effects on clinical gait and balance assessments over two years in 14 individuals with Parkinson’s disease. Methods: Computerized gait and balance evaluations were performed without medication, and stimulation was in the off state for at least 12 h to best assess the …

Science And Mathematics Teacher Communities Of Practice: Social Influences On Discipline-Based Identity And Self-Efficacy Beliefs, Samuel J. Polizzi, Yicong Zhu, Joshua W. Reid, Brandon Ofem, Sara Salisbury, Michael Beeth, Gillian Roehrig, Margaret J. Mohr-Schroeder, Keith Sheppard, Gregory T. Rushton

Science, Technology, Engineering, and Mathematics (STEM) Education Faculty Publications

Background
Teacher communities of practice, identity, and self-efficacy have been proposed to influence positive teacher outcomes in retention, suggesting all three may be related constructs. Qualitative studies of communities of practice can be difficult to empirically link to identity and self-efficacy in larger samples. In this study, we operationalized teacher communities of practice as specific networks related to teaching content and/or pedagogy. This scalable approach allowed us to quantitatively describe communities of practice and explore statistical relationships with other teacher characteristics. We asked whether these community of practice networks were related to identity and self-efficacy, similar to other conceptualizations of …

Pyrrolizidine Alkaloid Content And Seed Toxicity In Crotalaria Species, J. A. Mosjidis, I. Khan, J. Hess

IGC Proceedings (1977-2023)

No abstract provided.

How A City's Pilot Project Can Influence A State's Brownfields Program, Bonnie Biemer

Journal of Natural Resources & Environmental Law

No abstract provided.

Risk Assessment, Redevelopment, And Environmental Justice: Evaluating The Brownfields Bargain, John S. Applegate

Journal of Natural Resources & Environmental Law

No abstract provided.

Learning From Brownfields, Wendy E. Wagner

Journal of Natural Resources & Environmental Law

No abstract provided.

Radical Restructuring Of Environmental Policy To Preserve Biodiversity In Southern Africa: Malawi At The Crossroads, Tracy Dobson

Journal of Natural Resources & Environmental Law

No abstract provided.

Discovering And Enforcing A Human Right To Environmental Protection, Mélanne Andromecca Civic

Journal of Natural Resources & Environmental Law

No abstract provided.

How The Legal System Has Failed The Environmental Justice Movement, Karen Smith

Journal of Natural Resources & Environmental Law

No abstract provided.

Application Of The Audit Privilege To Occupational Safety And Health Audits: Lessons Learned From Environmental Audits, Margaret S. Lopez

Journal of Natural Resources & Environmental Law

No abstract provided.

Science And Law: The Quest For The Neutral Expert Witness. A View From The Trenches, Carl B. Meyer

Journal of Natural Resources & Environmental Law

No abstract provided.

Chromosome Xq23 Is Associated With Lower Atherogenic Lipid Concentrations And Favorable Cardiometabolic Indices, Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. De Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic variation is understudied for blood lipids in large sample sizes. We now analyze genetic and blood lipid data in a high-coverage whole X chromosome sequencing study of 65,322 multi-ancestry participants and perform replication among 456,893 European participants. Common alleles on chromosome Xq23 are strongly associated with reduced total cholesterol, LDL cholesterol, and triglycerides (min P = 8.5 × 10⁻⁷²), with similar effects for males and females. Chromosome Xq23 lipid-lowering alleles are associated with reduced odds for CHD among 42,545 …

An Experimental Education Project For Consultations Of Older Adults During The Pandemic And Healthcare Lockdown, Agnieszka Neumann-Podczaska, Mikołaj Seostianin, Konrad Madejczyk, Piotr Merks, Urszula Religioni, Zofia Tomczak, Sławomir Tobis, Daniela C. Moga, Melody Ryan, Katarzyna Wieczorowska-Tobis

Pharmacy Practice and Science Faculty Publications

Objective: To develop a mentor-supervised, interprofessional, geriatric telemedicine experiential education project in response to the COVID-19 pandemic. Method: Medical and pharmacy students collaborated via remote consultations to address the coexistence of multimorbidity and polypharmacy in geriatric patients. In-depth interviews of students and patients as well as Likert scale-based telephonic survey were performed for a comprehensive evaluation of the project’s significance. Results: To date, 49 consultations have been conducted. Remote consultations performed by medical and pharmacy students working collaboratively were beneficial for both students, participants. Conclusions and Practice Implications: This experimental education project provided students with authentic challenges while simultaneously delivering …

Alternative Community Nutrition Experiential Learning Opportunities For Dietetic Interns During Covid-19, Courtney T. Luecking, Elizabeth Combs, Heather Norman-Burgdolf

Dietetics and Human Nutrition Faculty Publications

In response to the COVID-19 pandemic, collaboration among faculty in the Department of Dietetics and Human Nutrition at the University of Kentucky yielded two, four-week virtual experiential learning opportunities with Cooperative Extension for 19 dietetic interns. Remote experiences focused on development of new programming regarding the role of nutrition in the prevention/management of the most prevalent chronic diseases affecting Kentuckians and translating an existing social marketing program that promotes quality family time through preparation of nutritious, affordable home-cooked meals. Weekly assignments took ~10 hours, included individual and groupwork, and came together to create program packages encompassing commonly used products (e.g., …

Southeastern Law Librarian Spring 2021, Seaall

Newsletters

No abstract provided.