Digital Commons Network^™

Role Of Hellenic Range And Pasture Society In Technology Interaction And Policy Evolution, T. G. Papachristou, P. D. Platis, V. Papanastasis, A. Ainalis

IGC Proceedings (1977-2023)

The Hellenic Range and Pasture Society (HRPS) was founded in 1992 and is a non-profit scientific association. It is composed of 74 members with a common interest in the study, management, and rational use of rangelands and related ecosystems (e.g. pasturelands). The objectives for which the corporation was established are: a) to develop an understanding of rangeland ecosystems and of the principles applicable to the management of rangeland resources (soil, plants, water, and animals), b) to assist all who work with rangelands and pasturelands to keep abreast of new findings and techniques in the science and art of rangeland and …

Role Of The Grassland Society Of Bosnia And Herzegovina In Grassland Agriculture, S. Alibegovic-Gbic, M. Bezdrob

IGC Proceedings (1977-2023)

The biggest part of Bosnia and Herzegovina is covered with hilly and mountainous terrain, which, from the agricultural perspective, determines the manner of soil usage. Of all agricultural areas in Bosnia and Herzegovina, 55.49% are covered by grassland with that figure increasing to 79.14% in mountainous regions. Therefore, grassland agriculture and its cousin livestock production are the most significant part of the Bosnian economy. In the current situation natural grasslands are largely neglected and give a low yield of forage of low quality. Many areas are completely abandoned and have been gradually overgrown with weeds and bushes. Yet a special …

American Forage And Grassland Council Technology Interaction And Policy Development, E. K. Twidwell, W. A. Tucker

IGC Proceedings (1977-2023)

The American Forage and Grassland Council (AFGC) is a national organisation which has been in existence since 1968. Membership of AFGC is about 2,500. The membership of AFGC is divided into three main sectors: private, public and industry. The private sector has the largest membership (60%), and private members are usually producers that are engaged in some type of agricultural enterprise involving the use of forages. The public sector members (30%) are educators and other government agency personnel that work with the general public. The industry sector (10%) involves various companies that deal with the forage industry. The AFGC Board …

Change In Grassland Science: Implications For Training, Research And Grassland Societies, G. Lemaire, R. J. Wilkins, J. Hodgson

IGC Proceedings (1977-2023)

In most of the world the priority for production-oriented research has been succeeded by the need for grassland research to focus on systems which satisfy requirements relating to the stability and protection of land, water and atmospheric resources and to biodiversity, in addition to production efficiency. This dictates not only a new approach to research, but also new approaches for the organisation of research, the training and development of research scientists and the activities of Grassland Societies and associated organisations.

Citizen Scientists: Efforts By The Tri-Societies To Inject Science Into Us Policymaking, E. Bergfeld, K. Glasener

IGC Proceedings (1977-2023)

The Tri-Societies (American Society of Agronomy, Crop Science Society of America and Soil Science Society of America), the largest life science professional societies in the United States (US) dedicated to the agronomic, crop and soil sciences, encompass approximately 18,000 members globally and include approximately 14,000 certified professionals who are a direct conduit to the farming communities across the US. The Tri-Societies' US-based federal science policy programmes have been active for decades. There is a Washington, DC-based Director of Science Policy, Congressional Science Fellows (CSF) and Science Policy Interns.

Uk Libraries' "Wildcat Histories:" Preserving Student Activist Social Media Content, Ruth E. Bryan, Taylor C. Leigh, Emily B. Collier

Library Presentations

In this presentation, we describe the current web archiving program at the University of Kentucky Libraries; provide an overview of the "Wildcat Histories" activist student organization social media preservation project, funded by Project STAND; discuss the technical aspects of the "Wildcat Histories" project; and the project's current status and lessons learned.

Effectiveness Of Individualized Counseling On The Duration Of Exclusive Breastfeeding: Study Protocol For A Multicenter, Randomized, Parallel, And Open Clinical Trial., Mariana Torreglosa Ruiz, Elisa Da Conceição Rodrigues, Karine Emanuelle Peixoto Oliveira Da Silva, Cynthya Viana De Resende, Michele Curcino Cavalcanti, Luciano Marques Dos Santos, Monika Wernet, Ana Letícia Monteiro Gomes, Marialda Moreira Christoffel, Maria Beatriz Guimarães Raponi, Jéssica Aparecida Da Silva, Jacqueline Faria De Oliveira, Divanice Contim, Ana Linares

Nursing Faculty Publications

BACKGROUND: Despite the benefits of breastfeeding, early weaning is a reality, so less than 50% of children worldwide and in Brazil are on exclusive breastfeeding in the sixth month of life. A strategy to counteract this scenario is breastfeeding counseling. This study aims to verify the effectiveness of individualized counseling by nurses trained in breastfeeding counseling, on the duration of exclusive breastfeeding, compared to standard care.

METHODS: Multicenter, randomized, parallel, and open clinical trial, with primiparous women aged over 18 years, hospitalized in rooming-in wards at participating centers and hemodynamically stable, aware, and oriented, who had a single-fetus pregnancy and …

A Mini-Review Of What Matters In The Management Of Nas, Is Esc The Best Care?, Enrique Gomez Pomar

Pediatrics Faculty Publications

As the use of opioids and polysubstance by pregnant women has increased over the years, there has also been a sharp increase in cases of neonatal abstinence syndrome (NAS). Classically, infants affected by NAS have been cared for in neonatal intensive care units resulting in an increase of healthcare expenditure and resource utilization as well as separation from the families. Consequently, the Eat, Sleep, and Console (ESC) tool was developed and promoted as a novel method that focuses on maternal/infant dyad during hospital stay while decreasing the use of pharmacological interventions and therefore decreasing the length of stay and healthcare …

Making Home: The Role Of Social Networks On Identity, Health, And Quality Of Life Among Rural Lesbian And Gay Older Adults, Marc A. Guest, Elizabeth G. Hunter, Nancy E. Schoenberg

UK CARES Faculty Publications

Background and Objectives: Gay and lesbian older persons face a host of health inequalities related to their identity as they age. Challenges to health access and appropriate social support may be even more exacerbated for those living in rural environments; this may be due to the lack of supportive and affirming social connections. This project aimed to explore and describe the social networks and the relationship of these social networks to identity, health, and quality of life of gay and lesbian individuals in rural communities.

Research Design and Methods: Social network data on network type, size, and social capital were …

Transportation Infrastructure Needs In The Central Appalachian Basin To Support Core-Cm, Bryan Gibson, Robin Baskette, Doug Kreis

Kentucky Transportation Center Research Report

With demand for coal from the Central Appalachian Basin waning, coalitions and organizations throughout the region have sought to diversify the region’s economy. However, the potential exists to use coal and coal-based resources to produce new and innovative products and kick start economic growth in the basin. This includes carbon ore, rare earth and critical minerals (CORE-CM), other minerals, and waste streams. If the region is to take advantage of these economic growth opportunities, transportation infrastructure must be developed and maintained in a sound condition. Reliable roads, highways, and bridges provide rural areas with access to capital, labor, and markets …

Enhanced Bypass Of Pd-L1 Translation Reduces The Therapeutic Response To Mtor Kinase Inhibitors, Yanan Cao, Qing Ye, Murong Ma, Qing-Bai She

Markey Cancer Center Faculty Publications

Increased PD-L1 expression in cancer cells is known to enhance immunosuppression, but the mechanism underlying PD-L1 upregulation is incompletely characterized. We show that PD-L1 expression is upregulated through internal ribosomal entry site (IRES)-mediated translation upon mTORC1 inhibition. We identify an IRES element in the PD-L1 50-UTR that permits cap-independent translation and promotes continuous production of PD-L1 protein despite effective inhibition of mTORC1. eIF4A is found to be a key PD-L1 IRES-binding protein that enhances PD-L1 IRES activity and protein production in tumor cells treated with mTOR kinase inhibitors (mTORkis). Notably, treatment with mTORkis in vivo elevates PD-L1 levels and reduces …

Lung And Colorectal Cancer Disparities In Appalachian Kentucky: Spatial Analysis On The Influence Of Education And Literacy, Nicole Robertson Mph, Todd Burus, Lauren Hudson, Pamela C. Hull, Lee Park, Nathan L. Vanderford

Markey Cancer Center Faculty Publications

Low educational attainment and high cancer incidence and mortality rates have long been a challenge in Appalachian Kentucky. Prior studies have reported disparities in cancer incidence and mortality between Appalachian and non-Appalachian populations, but the influence of education on this disparity has not been extensively studied. Herein, all cancers and two cancer sites with available screenings (colorectal and lung) were joined with education indicators (educational attainment and literacy) and one geographic indicator across all 120 Kentucky counties. This dataset was used to build choropleth maps and perform simple linear and spatial regression to assess statistical significance and to measure the …

Forage Production And Nitrogen Status In Mixed Fodder Crops, G. Convertini, M. Maiorana, D. Ferri

IGC Proceedings (1977-2023)

In Southern Italy, the lack of rain during the summer period is one of the main factors limiting fodder crop production. Another very important parameter, linked to drought, is N fertilisation. In these conditions, it is necessary to find mixtures of legumes and grasses able to ensure good production and quality in the driest months, and to rationalise N fertilisation through control of the nutritional status of the crops at the beginning of spring. By this approach, it is possible to adjust N application during the cropping cycle. The aim of this research was to evaluate in a hilly area …

Response Of Guinea Grass (Panicum Maximum Jacq) To Application Of Cow Dung In South West Nigeria, Olufemi S. Onifade, Jimoh A. Olanite, Alaba O. Jolaosho, O. M. Arigbede, N. K. Tijani

IGC Proceedings (1977-2023)

The yield of forage species from the world's grazing land is limited by poor soil and unproductive species (Jones & Wild, 1975; Cooke, 1982). The use of manure on pasture land not only represents a low cost disposal method but also a means of recycling nutrients for plant growth and counteracting the decreasing organic matter content in most agricultural soils. In agro-pastoral production systems, the interaction between crops and livestock is important. Manures are used mainly to complement inorganic fertiliser in the production of food crops. There is a dearth of information on the response of pasture grass to application …

Recent Advances In Stylosanthes Research In Tropical America, Bela Grof, Celso D. Fernandes, Jaqueline R. Verzignassi

IGC Proceedings (1977-2023)

The potential of neotropical savannas is very large for pasture-based livestock systems. There are 250 million ha of well-drained lowland savannas in the American tropics. Over 200 million ha are situated in the Cerrados region of Brazil. The Cerrados support 42% of the national herd. Although these ranges support large populations of livestock, productivity is generally low. Poor nutritive value of native pastures and monospecific swards of Brachiaria spp. is the principal cause of this low productivity, especially in the dry season when these grasslands often provide no more than 60% of the animal's maintenance requirements. The best option to …

Will Our Future Selves Thank Us? An Examination Of Born-Digital Curation Practices At Ukl, Megan M. Mummey, Sarah Dorpinghaus, Ruth Bryan, Emily Collier

Library Presentations

Cultural heritage resources are increasingly being produced and distributed digitally yet the world of physical materials has not declined. Analog-based archival theory and practice is still relevant, but born-digital formats make acquisition, appraisal, resource allocation, collection management, and external relationships much more challenging. During this session, four archivists and librarians from the University of Kentucky Libraries (UKL) will share their current challenges and successes working with different aspects of born-digital stewardship. They will share practical tips, tools, policies, and mental frameworks to help attendees identify gaps, pitfalls, and opportunities in digital stewardship at their own institutions. Sarah Dorpinghaus will provide …

Rac Survey Results - Herd Quant Report - June 2023, Baron G. Wolf, Erin Wallett, Katherine Robershaw, Min Xiao

Research Analytics Academic Publications

This is a quantitative report from the survey results from the Higher Education Research & Development Survey research project funded by the National Science Foundation (award no. 2215223). This is a result of the HERD-section of this national survey collection.

Preservation Perseverance: Archiving Social Media Content, A University Of Kentucky/Latino Student Union Collaboration, Ruth E. Bryan, Taylor C. Leigh, Emily B. Collier

Library Presentations

The voices of activist student leaders and organizations are crucial to preserve, whether it be in a formal archives or as part of an archiving process undertaken by individuals and groups to preserve their legacies. Increasingly, these voices are found in social media and other online and web platforms that are difficult to preserve. Wildcat Histories is a year-long, grant-funded collaboration between the University of Kentucky Libraries and the University of Kentucky Latino Student Union (LSU) to research the best technologies for (as of July 2023) and then carry out the preservation of activist student organization social media content. The …

V2g Optimization For Dispatchable Residential Load Operation And Minimal Utility Cost, Rosemary E. Alden, Ashutosh Timilsina, Simone Silvestri, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Electric Vehicles (EVs) are gaining popularity among consumers and are expected to play a significant role in the future of transportation. Within this paper, a reverse auction is formulated through an optimization problem to minimize the utility energy cost using Vehicle-to-Grid (V2G) operation, as well as transition residential communities to dispatchable aggregate constant load profiles for demand response (DR). The evolution-ary V2G Auction (eV2GA), including the non-dominated sorting genetic algorithm (NSGA-II), is proposed for the formulated problem. It uses co-simulation with OpenDSS for power flow analysis as part of the objective function to account for physical constraints of infrastructure on …

Electric Water Heater Modeling For Large-Scale Distribution Power Systems Studies With Energy Storage Cta-2045 Based Vpp And Cvr, Rosemary E. Alden, Huangjie Gong, Tim Rooney, Brian Branecky, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

As the smart grid involves more new technologies such as electric vehicles (EVs) and distributed energy resources (DERs), more attention is needed in research to general energy storage (GES) based energy management systems (EMS) that account for all possible load shifting and control strategies, specifically with major appliances that are projected to continue electrification such as the electric water heater (EWH). In this work, a methodology for a modified single-node model of a resistive EWH is proposed with improved internal tank temperature for user comfort modeling and capabilities for conservation voltage reduction (CVR) simulations as well as Energy Star and …

Optimal Power Sharing Speed Compensation In On-Road Wireless Ev Charging Systems, Donovin Lewis, Omer Onar, Veda Prakash Galigekere, Mostak Mohammad, Dan Ionel

Electrical and Computer Engineering Graduate Research

Dynamic wireless charging of electric vehicles (EV) is an emerging technology with the potential to address range anxiety and reduce the size of batteries or provide charge sustaining operation. Charging demand for dynamic wireless charging systems (DWCS) varies greatly in response to location specific traffic behaviors including the number and speed of vehicles. This paper highlights the potential reduction of load variation with speed compensation and simulates opportunities to maximize the number of cars charged concurrently through ”power sharing” or altering power output to slower cars while maintaining a maximum delivered energy. An improved sub- minute model for synthetic traffic …

Merging Multiple Existing Geotechnical Databases, Charlie Sun, Brad Rister, Eileen Grady

Kentucky Transportation Center Research Report

This report discusses a project undertaken by Kentucky Transportation Center (KTC) researchers to create a comprehensive geotechnical database for highway planning, design, maintenance, and repair. The project consolidated multiple geotechnical data sources into a unified database accessible to Kentucky Transportation Cabinet (KYTC) staff, enabling informed decision making and improving project outcomes. Databases were merged with great attention to detail, ensuring data integrity and coherence. A geotechnical data collector app developed as part of the project supports convenient and efficient data collection in the field, even when phones or tablets lack network connectivity. A rockfall rating app and landslide hazard rating …

Co-Simulation Of Electric Power Distribution Systems And Buildings Including Ultra-Fast Hvac Models And Optimal Der Control, Evan S. Jones, Rosemary E. Alden, Huangjie Gong, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Smart homes and virtual power plant (VPP) controls are growing fields of research with potential for improved electric power grid operation. A novel testbed for co-simulation of electric power distribution systems and distributed energy resources (DERs), is employed to evaluate VPP scenarios and propose an optimization procedure. DERs of specific interest include behind-the-meter (BTM) solar photovoltaic (PV) systems as well as heating, ventilation, and air-conditioning (HVAC) systems. Simulation of HVAC systems is enabled by a machine learning procedure that produces ultra-fast models for electric power and indoor temperature of associated buildings that are up to 133 times faster than typical …

Realizing Innovation And Sustainability: A Case Study Of Macau Sar’S Smart City Development Capabilities, Yujia He, Felix Ter Chian Tan, Carmen Leong, Jingbo Huang, Don Rodney Junio

Patterson School of Diplomacy and International Commerce Faculty Publications

The emergence of digital technologies has transformed organizational innovation with important implications for a city, its economy and policymaking. Despite this, research on how capabilities underpin innovation through smart city initiatives is still lacking. To address this gap, we conduct an empirical investigation of smart city initiatives in Macau, a former Portuguese colony and now special administrative region (SAR) of China. The case study adopts a qualitative approach, using data collected through fieldwork observations and in-depth interviews with stakeholders, and analysis of secondary documents. The study develops a stage-based assessment of innovation capabilities related to the use of technologies in …

Novel Isolation Method Reveals Sex-Specific Composition And Neurotoxicity Of Small Extracellular Vesicles In A Mouse Model Of Alzheimer’S Disease, Ahmed Elsherbini, Zhihui Zhu, Zainuddin Quadri, Simone M. Crivelli, Xiaojia Ren, Hemendra J. Vekaria, Priyanka Tripathi, Liping Zhang, Wenbo Zhi, Erhard Bieberich

Markey Cancer Center Faculty Publications

We developed a new method to isolate small extracellular vesicles (sEVs) from male and female wild-type and 5xFAD mouse brains to investigate the sex-specific functions of sEVs in Alzheimer’s disease (AD). A mass spectrometric analysis revealed that sEVs contained proteins critical for EV formation and Aβ. ExoView analysis showed that female mice contained more GFAP and Aβ-labeled sEVs, suggesting that a larger proportion of sEVs from the female brain is derived from astrocytes and/or more likely to bind to Aβ. Moreover, sEVs from female brains had more acid sphingomyelinase (ASM) and ceramide, an enzyme and its sphingolipid product important for …

Quality Legume-Based Forage Systems For Contrasting Environments: Cost Action 852, A. Helgadottir, John Connolly, M. Fothergill, R. P. Collins, Claudio Porqueddu, Andreas Lüscher, M. T. Sebastia, Michael Kreuzer, M. Wachendorf

IGC Proceedings (1977-2023)

Agricultural systems that reduce environmental degradation, sustain agricultural productivity and economic viability, maintain stable rural communities, enhance the quality of life and respond to increasing demand for livestock products are promoted in developed countries. Though major challenges exist, forage legumes, adapted to a wide range of soil types, climatic conditions and management systems, will become increasingly important components of sustainable agricultural production systems in Europe. Temporal and spatial variation in legume performance often occurs. Compared to pure grass systems, legume-based systems may lead to increased N losses. To what extent ruminants can use the protein from forage legumes, and whether …

The Last Of Us In Therapy: How Mind-Controlling Fungi And Gut Bacteria Affect Your Mental Health, Anastasia Lyon

Journal of Pharmacology & Nutritional Sciences

The "psilocybiome" represents the mutually beneficial relationship between ourselves, our bacteria, and psychedelic drugs. This short review briefly discusses the benefits and limitations surrounding the potential for psychedelic therapy to synergize with gut bacteria to help regulate and maintain proper balance in the immune system, diet, and stress levels. Psychedelic therapy is a novel treatment strategy that has the potential to improve patient mental health, and, by identifying the types of gut bacteria present in patients, it can aid in personalizing medicine by determining how well their "psilocybiome" may respond.

Flood Fatalities In Eastern Kentucky And The Public Health Legacy Of Mountaintop Removal Coal Mining, W. Jay Christian, Beverly May, Jeffery E. Levy

UK CARES Faculty Publications

Heavy rains at night caused severe flooding in eastern Kentucky on 28 July 2022, resulting in 39 deaths. Using publicly available information, we assembled a database of these fatalities, including demographic characteristics and location of death. We perturbed fatality locations and plotted them on a topographical map highlighting mountaintop removal mining with valley fill sites, where mountaintops were excavated to mine thin seams of coal. This map reveals many flood fatalities occurred along rivers or streams near such sites. Previous research suggests that surface mining has contributed to the majority of land cover change in this region, and this has …

Accelerating Colorectal Cancer Screening And Follow-Up Through Implementation Science (Accsis) In Appalachia: Protocol For A Group Randomized, Delayed Intervention Trial, Electra D. Paskett, Aaron J. Kruse-Diehr, Jill M. Oliveri, Robin C. Vanderpool, Darrell M. Gray Ii, Michael L. Pennell, Bin Huang, Gregory S. Young, Darla Fickle, Mark Cromo, Mira L. Katz, Paul L. Reiter, Melinda Rogers, David A. Gross, Vickie Fairchild, Wendy Xu, Angela Carman, Jean M. Walunis, Ann Scheck Mcalearney, Timothy R. Huerta, Saurabh Rahurkar, Erika Biederman, Mark B. Dignan

UK CARES Faculty Publications

Appalachian regions of Kentucky and Ohio are hotspots for colorectal cancer (CRC) mortality in the USA. Screening reduces CRC incidence and mortality; however, screening uptake is needed, especially in these underserved geographic areas. Implementation science offers strategies to address this challenge. The aim of the current study was to conduct multi-site, transdisciplinary research to evaluate and improve CRC screening processes using implementation science strategies. The study consists of two phases (Planning and Implementation). In the Planning Phase, a multilevel assessment of 12 health centers (HC) (one HC from each of the 12 Appalachian counties) was conducted by interviewing key informants, …

Combination Therapy With Trastuzumab And Niraparib: Quantifying Early Proliferative Alterations In Her2+ Breast Cancer Models, Ameer Mansur, Patrick N. Song, Yun Lu, Andrew C. Burns, Luke Sligh, Eddy S. Yang, Anna G. Sorace

Markey Cancer Center Faculty Publications

HER2–targeted treatments have improved survival rates in HER2+ breast cancer patients, yet poor responsiveness remains a major clinical obstacle. Recently, HER2+ breast cancer cells, both resistant and responsive to HER2–targeted therapies, have demonstrated sensitivity to poly–(ADP– ribose) polymerase (PARP) inhibition, independent of DNA repair deficiencies. This study seeks to describe biological factors that precede cell viability changes in response to the combination of trastuzumab and PARP inhibition. Treatment response was evaluated in HER2+ and HER2– breast cancer cells. Further, we evaluated the utility of 3′–Deoxy–3′–[18F]–fluorothymidine positron emission tomography ([18F]FLT–PET) imaging for early response assessment in a HER2+ patient derived xenograft …