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Uk Law Notes, 2015, University Of Kentucky College Of Law

Annual Magazines

No abstract provided.

Quality Of Water From Tile Drains In Fields Treated With Poultry Litter In Mclean County, Kentucky, E. Glynn Beck, Lisa Y. Blue, David A. Atwood

Information Circular--KGS

Poultry litter (a mixture of feed, manure, and bedding material) is commonly used as a soil amendment to row-crop fields in western Kentucky. Because of feed additives, litter typically has elevated concentrations of contaminants, including metals and anions. These metals and anions can accumulate in the soil and therefore could be transported to surface water through drainage tiles. In order to assess water quality in tile drains, a pilot study was conducted in 2008 in McLean County, Kentucky, in which 10 tile drains and six drainage ditches were sampled for total metals and anions. Seven of the tile-drained fields were …

Proton Pump Inhibitors And Atrial Fibrillation, Dustin Hughes

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background

Proton pump inhibitors (PPIs) are widely used drugs in the United States. Atrial fibrillation (AF) affects 2.7 million people in this country and often leads to other serious medical conditions. There is a growing body of evidence suggesting that PPIs may be proarrhythmic. This study seeks to better appreciate the relationship between these popular drugs and the most common arrhythmia.

Methods

This is a nested case-control study using a large, nationally representative insurance database. Members with an incident AF diagnosis between 2007 and 2009 were identified. Each case was matched with one control member, using incidence density sampling, and …

Evaluation Of L-Methionine Bioavailability In Nursery Pigs, Jina Lim

Theses and Dissertations--Animal and Food Sciences

DL-Methionine (Met) has been conventionally used in swine diets with assumption of similar bioefficacy with L-Met. However, because L-Met is the form that is utilized by animals for protein synthesis, L-Met could, theoretically, be more available. Four experiments were conducted to evaluate L-Met bioavailability in nursery pigs with 21-day growth trials. A total of 105,105,112 and 84 crossbred pigs were used in Exp. 1, 2, 3 and 4, respectively. Each experiment had a low Met basal diet and 3 levels of the Met sources (DL-Met and L-Met). In addition to the basal diet, supplementation levels were 0.053%, 0.107% and 0.160% …

Anti-Cancer Activity Of Withaferin A In B-Cell Lymphoma., M K Mckenna, B W Gachuki, S S Alhakeem, K N Oben, V M Rangnekar, R C Gupta, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Withaferin A (WA), a withanolide from the plant, Ashwagandha (Withania somnifera) used in Ayurvedic medicine, has been found to be valuable in the treatment of several medical ailments. WA has been found to have anticancer activity against various solid tumors, but its effects on hematological malignancies have not been studied in detail. WA strongly inhibited the survival of several human and murine B cell lymphoma cell lines. Additionally, in vivo studies with syngeneic-graft lymphoma cells suggest that WA inhibits the growth of tumor but does not affect other proliferative tissues. We demonstrate that WA inhibits the efficiency of NF-κB nuclear …

Relationships Between Behavioral Measures And Productivity In Growing Beef Cattle, Kelsey Bruno

Theses and Dissertations--Animal and Food Sciences

The relationships between behavioral measures, growth performance, and immunocompetence in receiving beef steers were explored in three experiments. Specifically, exit velocity (EV) and objective chute score (OCS) were examined as temperament measures. In experiment 1, no main effects or interactions with degradable intake protein (DIP) or interactions between temperament measures were observed (P ≥ 0.11); however, high OCS steers had greater intake and gain:feed (P < 0.10) and slow EV steers had higher intake and gain (P < 0.10) than their counterparts. In experiment 2, during week two of social observations, dominance hierarchy rankings were dependent on OCS and EV (P < 0.05); slow EV steers also had increased antibody responses and gain (P < 0.10) and high OCS steers had increased gain (P < 0.10). In experiment 3, subjective chute scores and OCS were positively correlated (P < 0.01) and both EV and OCS treatments changed over time (P < 0.10); intake, vaccine titer response, and gain:feed responses to monensin were dependent on OCS treatment (P < 0.10). The studies suggest that temperament, measured by EV and OCS, affects growth performance and health related measures and is related to social dominance behavior in receiving beef steers.

Assessment Of The Technical And Economic Potential Of Automated Estrus Detection Technologies For Dairy Cattle, Karmella Ann Dolecheck

Theses and Dissertations--Animal and Food Sciences

Poor estrus detection can limit the reproductive performance of a dairy herd. One objective of this research was to evaluate an alternative method to traditional estrus detection in the form of automated monitoring technologies. To accomplish this, the first study considered the ability of automatically monitored parameters (activity, number of steps, lying bouts, lying time, feeding time, rumination time, and temperature) to detect estrus. A second study compared automated activity monitoring to timed artificial insemination as reproductive management strategies on commercial herds. The other objective of this research was to evaluate the economic potential of automated estrus detection technologies. This …

An Evaluation Of Precision Dairy Farming Technology Adoption, Perception, Effectiveness, And Use, Matthew Richard Borchers

Theses and Dissertations--Animal and Food Sciences

Precision dairy farming technologies provide a variety of functions to dairy farmers. Little is known about dairy producer perception of these technologies. A study was performed to understand dairy producer perception of parameters monitored by precision dairy farming technologies. Calving has potential to be predicted using these same parameters and technologies. A second study was performed using two commercially marketed technologies in calving prediction. In order for these technologies to generate accurate and useful information for dairy farm use, they must accurately quantify these parameters. The final study evaluated the accuracy of five commercially marketed technologies in monitoring feeding, rumination, …

Effects Of Post-Hatch Holding Time And Early Nutrition Strategies On Growth Performance, Carcass And Skeletal Characteristics Of Young Chickens, Marquisha A. Paul

Theses and Dissertations--Animal and Food Sciences

The study objectives of this thesis were to evaluate the effects of delayed feeding and specific aspects of the Programmed Nutrition (PN) feeding strategy (Alltech, Inc.) on growth performance, carcass characteristics, and skeletal characteristics of commercial broiler chicks through market age, as well as investigate the effects of breed and the PN feeding strategy on early growth and development. When commercial broiler chicks were fed reduced nutrient diets, delayed feeding decreased early growth performance and carcass yield (P<0.05), whereas post-hatch PN conditioning for 72 hours improved early growth performance and alleviated the negative effects of delayed feeding on carcass yield (P<0.05). Through market age, delayed feeding improved Gain: Feed (P<0.05), while PN had the opposite effect. Interactive effects and main effects of delayed feeding and PN were observed for tissue mineral concentration (P<0.05). PN lowered bone ash % (P<0.05) and increased meat oxidation of broiler chicks during storage (P<0.05). PN also had negative effects on early growth performance and bone breaking strength (P<0.05) of various meat-type breeds, but especially for non-commercial, moderate-growing or fast-growing breeds. In conclusion, PN may be suitable for commercial broiler chicks that experience delayed feeding and are fed reduced nutrient diets.

Algae Or Yeast Supplementation For Lactating Dairy Cows, Maegan E. Weatherly

Theses and Dissertations--Animal and Food Sciences

The objective of the first study was to quantify the effects of feeding Schizochytrium sp. microalgae (SP-1, Alltech, Inc., Nicholasville, KY) on milk fat and DHA content. Eight cows were fed: 0, 100, 300, or 600 g of algae per day. Fat percentage was greater (P < 0.05) for cows on treatments 0 g and 100 g than for cows on treatments 300 g and 600 g (P < 0.05). Docosahexaenoic acid in milk was greater for cows on treatment 300 and 600 than for cows on treatment 0 and 100 (P < 0.05).

The objective of the second study was to assess yeast supplementation effects on high and low forage dairy cow diets. Four cows were assigned to 1 of 4 treatments: 1) low forage (LF), 2) low forage with 10 g/d yeast (Yea-Sacc®; Alltech Inc., Nicholasville, KY; LFY), 3) high …

Assessing The Efficacy Of Automated Detection Of Estrus In Dairy Cattle, Lauren M. Mayo

Theses and Dissertations--Animal and Food Sciences

The detection of estrus continues to be a primary factor contributing to poor reproductive performance in modern dairy cattle. The objectives of this research were 1) to evaluate performance of automated detection of estrus using a reference standard of ovulation detection with temporal progesterone patterns 2) to evaluate the efficacy of parameters measured by automated detection of estrus systems 3) to evaluate the efficacy of alerts generated by several commercially available systems used for automated detection of estrus and 4) to determine the differences in these parameters among cows with or without poor health conditions at the time of estrus. …

Using The Indicator Amino Acid Oxidation Technique To Study Threonine Requirements In Horses Fed Different Feed Compositions, Chanhee Mok

Theses and Dissertations--Animal and Food Sciences

Threonine has been reported to be the second limiting amino acid in typical equine diets, but its actual requirement has not been determined in horses. The indicator amino acid oxidation (IAAO) method has been successfully used for evaluating amino acid metabolism and requirements in animals and humans. The objective of this research was to use the IAAO method to estimate threonine requirements in mature horses fed two different feed compositions. In the first study, 6 Thoroughbred mares (4 – 16 years old) received each of 6 levels of threonine intake in a high concentrate diet, in a randomly determined order. …

Impact Of Starch Source On Equine Hindgut Microbial Ecology, Brittany Elizabeth Davis Harlow

Theses and Dissertations--Animal and Food Sciences

Grain inclusion in equine diets can allow starch to reach the hindgut where bacteria compete for the substrate. The hypothesis was that starch introduction would cause a source-dependent press disturbance in equine fecal microflora. Fecal cell suspensions were prepared by differential centrifugation and re-suspension in media with ground corn, oats or wheat. At 24 h, corn had more amylolytics and Group D Gram-positive cocci (GPC), and fewer lactate-utilizing (LU) bacteria and lactobacilli than oats, with wheat being intermediate. Predominant amylolytics were identified by their 16S RNA gene sequence as Enterococcus faecalis (corn, wheat) and Streptococcus bovis (oats). In an in …

Loss Of Multidrug Resistance-Associated Protein 1 (Mrp1/Abcc1) Potentiates Doxorubicin-Induced Cardiotoxicity In Mice, Wei Zhang

Theses and Dissertations--Toxicology and Cancer Biology

Doxorubicin (DOX) is a broad-spectrum and effective chemotherapeutic agent, but its use in oncologic practice is limited by dose-dependent cumulative cardiotoxicity. DOX-induced cardiotoxicity is in large part due to its ability to cause oxidative stress. Multidrug resistance associated protein 1 (MRP1/ABCC1) is a member of the ATP-binding cassette (ABC) transporter superfamily. By effluxing a wide variety of endogenous and exogenous substrates, Mrp1 plays important physiological roles in multiple tissues and also protects normal tissues against toxicants. However, the role of MRP1 in heart is largely unknown.

The role of Mrp1 in DOX-induced cardiotoxicity was investigated in Mrp1 null (Mrp1-/-) and …

Narrating Rewilding: Shifting Images Of Wilderness In American Literature, Aaron Andrew Cloyd

Theses and Dissertations--English

Narrating Rewilding analyzes interactions between imaginative writings and environmental histories to ask how novels and creative nonfiction contribute to conversations of wilderness rewilding. I identify aspects of rewilding in Cormac McCarthy’s All the Pretty Horses, Marilynne Robinson’s Housekeeping, and Terry Tempest Williams’s Refuge within a context of William Cronon’s and James Feldman’s works of environmental history, and I argue that the selected imaginative works offer alternative ramifications of rewilding by questioning Cronon’s and Feldman’s anthropocentric basis.

While Cronon and Feldman argue that a rewilding wilderness expresses interconnections between human history and expressions of nature, and that a return of …

Servsafe® Exam: Student's Memory Retention Two Years Later, Laura E. Tincher

Theses and Dissertations--Nutrition and Food Systems

This study analyzed the memory retention of University of Kentucky Dietetic and Hospitality students as it relates to food safety and sanitation knowledge originally presented on the ServSafe® certification exam. Dietetic and hospitality students take the ServSafe® certification course during the sophomore year of their degree program, but they are responsible for the sanitation and food safety information throughout their entire program of undergraduate study. The final sample consisted of 25 participants, with 84% (n=21) in the Dietetics program and 16% (n=4) in the Hospitality, Management and Tourism program. The mean difference in total score, domain one, domain two, domain …

Pharmacologic Induction Of The Melanocotin 1 Receptor (Mc1r) Pathway Provides Protection Against Sunburn And Enhances Expression Of Antioxidant Enzymes In The Skin, Alexandra Amaro-Ortiz

Theses and Dissertations--Toxicology and Cancer Biology

The inability to tan properly after sun exposure strongly correlates with increased incidence of skin cancer. The melanocortin 1 receptor (MC1R) is a transmembrane Gs-coupled cell surface receptor found on epidermal melanocytes that transmits pro-survival and pro-differentiation signals mediated by the second messenger cAMP. Humans carrying loss-of-function polymorphisms in MC1R signaling exhibit higher incidences of skin cancers including melanoma.

This study focused on the physiologic effects of topical application of forskolin, an adenylate cyclase activator, in extension (Mc1r^e/e) K14-SCF animals, which model the fair-skinned UV-sensitive human. Twice daily application of the drug promoted accelerated pigmentation, increased skin darkening …

Role Of Caveolin-1 And Nrf2 In Nutritional Modulation Of Pcb Toxicity, Michael C. Petriello

Theses and Dissertations--Toxicology and Cancer Biology

Cardiovascular disease is the leading cause of mortality in Western societies and is linked to multiple modifiable risk factors including lifestyle choices. Emerging evidence implicates exposure to persistent environmental pollutants, such as polychlorinated biphenyls (PCBs), as a risk factor for the development or progression of cardiovascular disease. To reduce disease risks, it is critical to identify sensible means of biomedically reducing the toxicity of persistent organic pollutants and related environmental stressors.

First, we tested a hypothesis that endothelial cell inflammation and subsequent cardiovascular toxicity initiated by coplanar PCBs is modulated by the crosstalk between caveolae and Nuclear factor (erythroid-derived 2)-like …

Ecohydraulic Investigation Of Diatoms In A Bedrock-Controlled Stream, Alex M. Rittle

Theses and Dissertations--Geography

Recent studies within the past decade or so have shown the importance of algae in geomorphic and hydrologic processes of lotic systems. However, the ecohydraulic role of algae in bedrock systems has largely been ignored. In addition, the utility of algae as indicators of channel dynamics have often been assumed by geomorphologists, but relatively few studies have examined this relationship. The purpose of this study was to determine whether algae, specifically diatoms, are useful indicators of channel geomorphological dynamics, and to examine if distinct habitats or biotopes typical in fluviokarst and bedrock systems provide unique habitat space for diatoms, and …

Environmental Governance In The Carbon Economy: Regulating Greenhouse Gas Emissions In California's Cap-And-Trade Program, Patrick M. Bigger

Theses and Dissertations--Geography

Since 2006 California has been pursuing the most ambitious climate change policy in the United States, implementing a suite of greenhouse gas reduction measures ranging from automobile refrigerant disposal rules to clean energy standards for electric power utilities. The most significant of these measures is the creation of a cap‐and‐trade program. Through this program, regulators seek to create a knowable price‐signal to incentivize emissions reductions among polluters. Using a suite of ethnographic methods, this dissertation looks at the people, ideas, and institutions that have been mobilized in the creation of California’s cap‐and‐ trade program.

Substantively, the dissertation engages with three …

A Comprehensive Understanding Of Corpse Management In Termites, Qian Sun

Theses and Dissertations--Entomology

Undertaking behavior is the disposal of dead individuals in social colonies to prevent potential pathogenic attack. This behavioral trait has convergently evolved in social insects (primarily termites, ants, and honeybee), and is considered an essential adaptation to social living. In honey bee and ants, workers recognize dead colony members through the postmortem change of chemical profile, and corpses are usually removed out of nest. However, in termites, little is known about the behavioral pattern, chemical cue or molecular basis. In the eastern subterranean termite, Reticulitermes flavipes, this study investigated undertaking behavior toward corpses of different origins and postmortem times. …

Nitrogen Management Of Forages In Relation To Gaseous Emissions – New Approaches And Considerations, Shabtai Bittman, Derek Hunt

IGC Proceedings (1977-2023)

Forages have a high N demand, a long growing season, and an effective root system all contributing to effective nutrient capture. However forages are restrictive in methods available for mitigating gaseous losses both as NH₃ and as N₂O, due to both practical and cost considerations. Strategies are needed to address the challenges of both N efficiency and N losses. Agronomic techniques in long term experiments can enhance estimates of N loss pathways and N efficiency, and demonstrate the importance of integrated multinutrient approaches. The dual manure stream concept divides manure into a thin fraction suitable as an …

Impact Of Market Forces On Product Quality And Grassland Condition, David L. Michalk, Jianping Wu, Warwick B. Badgery, David R. Kemp

IGC Proceedings (1977-2023)

Meeting demands for livestock products which are predicted to more than double during the next 20 years, is central to the challenge of feeding the world sustainably. Smallholders will play a key role in achieving global security in animal protein. However, this requires a shift from subsistence to market-oriented farming where production efficiency not the number of livestock is the key focus with the aim of producing ‘more from less’. For grassland-based ruminant production, reducing stocking rate from current unsustainable levels under subsistence management is an essential first step to producing more production and profit from fewer animals. This is …

Stakeholders Integration For Sustainable Use Of Temperate Forage/Livestock Agriculture, Garry D. Lacefield, Don Ball

IGC Proceedings (1977-2023)

Forage/livestock production is complex, and best management options are often site-specific, but some concepts have broad application. The intent of this article is to provide an overview of research-based management approaches that the authors believe are necessary to ensure the sustainability of forage/livestock farms. This overview discussion is needed because livestock agriculture is changing, thus creating both challenges and opportunities for producers. In the last 30 years, beef numbers in the USA have declined by 20%, but production per cow has more than doubled, resulting in increased total production on less land with fewer animals. Similar statistics exist for the …

Socio-Cultural Factors Challenging Development Interventions In Cattle Production In The Remote Areas Of Vietnam, Duong-Nam Ha, Pham-Van Hung, Tran-The Cuong, Ninh-Xuan Trung, Tran-Van Long, Laurie Bonney, Peter A. Lane, Guillaume Duteurtre, Stephen Ives

IGC Proceedings (1977-2023)

The northwest highlands of Vietnam are characterized by high altitude, low infrastructure, and low population densities composed of a wide diversity of different ethnic groups. Their socio-cultural characteristics strongly influence their lifestyle and production systems, including agricultural activities. The majority of these people have suffered from slow economic development, with the highest poverty rate in the country. This is a real need for plausible interventions where behavioral changes of smallholders throughout local value chains would be a critical foundation. Our project implemented in this context of development in the Northwest highlands of Vietnam aims to understand the role of socio-cultural …

Changing Grassland Scenario In Developing Countries--Economical And Social Perspective, Abule Ebro

IGC Proceedings (1977-2023)

Grasslands are mainly used for livestock production in developing countries although they have been facing contradictory pressures, i.e., increased demand for natural resources and animal products to cope with rising human populations. On the other, there is a need to preserve the environment and ecosystem. This paper reviewed the causes of grassland changes, the economic and social perspective of changing grasslands with more emphasis on dry lands. Different indicators were used to assess the economic (livestock production, wildlife and tourism, crop production, ecosystem services) and social (traditional institutions, mobility, land tenure and grazing systems) perspectives of changing grassland. The major …

Conservation Of Grassland Plant Genetic Resources Through People Participation, D. R. Malaviya, Ajoy K. Roy, P. Kaushal

IGC Proceedings (1977-2023)

Agrobiodiversity provides the foundation of all food and feed production. Hence, need of the time is to collect, evaluate and utilize the biodiversity globally available. Indian sub-continent is one of the world’s mega centers of crop origins. India possesses 166 species of agri-horticultural crops and 324 species of wild relatives. India is reported to have five grass covers identified. There have been almost nil human interference in terms of selection pressure; hence, the biodiversity is well conserved in these grazing lands. There is need of a system approach to understanding biodiversity that moves significantly beyond taxonomy and species observations. In …

Breeding Strategies To Improve Fodder Legumes With Special Emphasis On Clover And Medics, Ajoy K. Roy, D. R. Malaviya, P. Kaushal

IGC Proceedings (1977-2023)

In India, Forage has a unique integration of agriculture and animal industry in diversified rich cultural environment. Greater part of rural economy in India relies much upon mixed farming system, a well-knit combination of crop production and livestock rearing. In India, grazing-based livestock husbandry plays an important role in the rural economy as around 50% of animals depend on grazing. Pasturelands over an area of 12 Mha constitute the main grazing resources that are available. Nearly 30 pastoral communities in hilly or arid/semi-arid regions in northern and western parts of India, depend on grazing-based livestock production. Nomadic pastoralism, a traditional …

Front Matter [23rd International Grassland Congress Proceedings], National Organizing Committee, International Grassland Congress

IGC Proceedings (1977-2023)

No abstract provided.

Healthcare Industry Injuries By Patient Contact Status In Kentucky, 2012-2014, Kristen Ranzenberger

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Objectives

The healthcare industry continues to have a high number of reported injuries. The purpose of this study was to 1) characterize healthcare industry injuries by patient contact status; 2) identify the occupations associated with healthcare injuries by patient contact status; and 3) determine healthcare injury rates by occupation, to gain a better understanding of healthcare industry compensated injuries , and better target healthcare industry safety practices and programs.

Methods

Workers’ Compensation first reports of injuries (FROI) from the healthcare industry in Kentucky were categorized into injuries involving in direct patient contact vs. injuries without direct patient contact using narrative …