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Articulatory-Wavenet: Deep Autoregressive Model For Acoustic-To-Articulatory Inversion, Narjes Alsadat Agha Seyed Mirza Bozorg

Theses and Dissertations--Electrical and Computer Engineering

Acoustic-to-Articulatory Inversion, the estimation of articulatory kinematics from speech, is an important problem which has received significant attention in recent years. Estimated articulatory movements from such models can be used for many applications, including speech synthesis, automatic speech recognition, and facial kinematics for talking-head animation devices. Knowledge about the position of the articulators can also be extremely useful in speech therapy systems and Computer-Aided Language Learning (CALL) and Computer-Aided Pronunciation Training (CAPT) systems for second language learners. Acoustic-to-Articulatory Inversion is a challenging problem due to the complexity of articulation patterns and significant inter-speaker differences. This is even more challenging when …

Cover Crops And Cover Crop Mixes: Stratification Of Biological Effects, Landon M. Gibbs

Theses and Dissertations--Plant and Soil Sciences

The potential nutrient cycling benefits from legumes (e.g. N₂-fixation) and the high biomass potential of cereal rye are well known. Further studies are warranted to evaluate bi-culture mixtures and their effects on soil nutrient stratification and microbial enzyme activity because these two properties may be differently expressed (enhanced) by legume/grass mixes. The objectives of this study were: (1) show different cover crops and cover crop mixes containing grasses and legumes differentially stratify carbon and N; (2) show the change in microbial enzyme activity in soils planted with individual cover crops relative to cover crop mixes; 3) determine the …

Nickel Speciation, Microbial Community Structure, And Chemical Attributes In The Rhizosphere Of Nickel Hyperaccumulating And Non-Accumulating Plants Growing In Serpentine Soils, James W. Morris

Theses and Dissertations--Plant and Soil Sciences

Serpentine soils are formed from weathering of serpentinite, the ultramafic parent material that provides serpentine soils with their unique identity. Weathering of serpentinite results in a plethora of edaphic factors that impose strong selection pressures on plant life, with high magnesium (Mg) to calcium (Ca) ratio, low fertility, and high levels of geologically derived metals such as cobalt (Co), chromium (Cr), and nickel (Ni). Appropriately, plant life on serpentine soils is often specialized, sparse, and endemic which in turn affects the ecosystems that develop on serpentine soils from the landscape scale down to the physiology of their inhabitants. At the …

Regulatory Networks During Seed Development, Ran Tian

Theses and Dissertations--Plant and Soil Sciences

Seeds make up approximately 70% of the human diet directly so understanding regulatory mechanisms to generate a seed and the embryo it contains is fundamentally important. The LAFL genes encode transcription factors (TF) that are critical for seed development. Three members of LAFL, LEAFY COTYLEDON2 (LEC2), ABSCISIC ACID3 (ABI3) and FUSCA3 (FUS3), are B3 domain factors that bind DNA motifs called RY motifs. While LEC2 is expressed earlier in embryo development, ABI3 and FUS3 are expressed during later development. All three of these TFs can induce embryo-specific programs after completion of germination to different extents up to and including formation …

A Biophysical Investigation Of Stability, Ligand Binding, And Iron State Of Cyp102a1, Catherine A. Denning-Jannace

Theses and Dissertations--Chemistry

Cytochrome P450s (CYPs) are cysteine ligated Fe-heme monooxygenases that are found in all domains of life. In mammals, they have a role in xenobiotic metabolism and steroid synthesis, making them a fundamental requirement for survival. In addition, their ability to perform a variety of chemical reactions on an array of substrates makes CYPs highly sought for biotechnical applications such as wastewater remediation, production of potential drug candidates, and creation of drug metabolites. By mutating specific amino acids, these enzymes can be engineered to change their substrate binding profiles and achieve stereo- and regio-specific chemistry. While these mutations are essential to …

New Single Molecule In Vivo And Ex Vivo Methods To Understand The Physiological Effects Of Nicotine Use, Xu Fu

Theses and Dissertations--Chemistry

The consumption of tobacco products leads to several health risks, including respiratory diseases, cardiovascular diseases, and many different cancers. Nicotine, the primary addictive compound in tobacco, acts on the cholinergic system through nicotinic acetylcholine receptors (nAChRs), which is believed to be an essential component of addiction. However, the lack of a complete understanding of the neurobiological mechanisms of nicotine abuse is one of the primary barriers to finding potent therapeutics for smoking cessation. Single-molecule imaging is an ideal tool to study molecular mechanisms of protein and physiological changes both in vitro and in vivo. In this dissertation, our research …

A Framework For Heterologous Biosynthesis Of Natural Products In Mammalian Cells Via Polymer-Mediated Transfections, Logan Warriner

Theses and Dissertations--Chemical and Materials Engineering

With the promise to treat a multi-faceted list of serious inherited and acquired diseases, such as cancer, neurodegenerative and infectious diseases, and inherited genetic indications, gene therapy has continued to push the boundaries of traditional medicine since its earliest implementation. While much progress has been made, clinical success has largely remained elusive. Immunogenicity, difficulty producing commercially relevant quantities, and having a limited genetic payload still limits the ability of viruses to act as directed delivery agents for genetic material. As such, researchers have turned to cationic synthetic materials as a means of delivering nucleic acids, which can circumvent the immune …

A Thermodynamic And Feasibility Study Of Green Solvents For The Fabrication Of Water Treatment Membranes, Xiaobo Dong

Theses and Dissertations--Chemical and Materials Engineering

Nonsolvent induced phase separation (NIPS) has been widely used to fabricate polymeric membranes. In NIPS, a polymer is dissolved in a solvent to form a dope solution, which is then cast on a substrate and immersed in a nonsolvent bath, where phase inversion occurs. Petroleum-derived organic solvents, such as N-Methyl-2-Pyrrolidone (NMP) and Dimethylacetamide (DMAc), have been traditionally used to fabricate polymeric membranes via NIPS. However, these solvents may have negative impacts on environmental and human health; therefore, using greener and less toxic solvents, preferably derived from biomass, is of great interest to make membrane fabrication sustainable. In this dissertation, two …

Heart Tissue Reconstruction By Light-Controlled Cell Adhesion, Patterning And Alignment On Decellularized Scaffolds, Cong Li

Theses and Dissertations--Chemical and Materials Engineering

There is an urgent demand for engineered tissues and organs because of extremely limited donor tissues available for transplant. The challenge of tissue rejection has motivated many researchers to try to remove all of the cells from a heart and then add back in patient matched cells. These recellularized hearts are a promising avenue towards a functional bioartifical heart that is less likely to be rejected. Decellularized extracellular matrix (ECM) scaffolds generated from animal hearts do not have the cellular components that elicit immune rejection in patient, and they also preserve the native heart tissue structure. While decellularization techniques are …

Interfaces In Lead-Free Tin Perovskite Photovoltaics: An Investigation Of Energetics, Ion Mobility, Surface Modification, And Performance, Alex Boehm

Theses and Dissertations--Chemistry

Halide perovskites have generated tremendous interest as low-cost semiconductors for optoelectronics, such as photovoltaics, lasers, and light emitting diodes due to their extraordinary optical and transport properties. Perovskite photovoltaics in particular have demonstrated a meteoric rise in power conversion efficiencies and drawn considerable interest as a next-generation solar energy technology. The rapid development has centered around lead-based derivatives, and concerns regarding the toxicity of lead has sparked interest in low toxicity and more environmentally friendly perovskite derivatives. In this regime tin (Sn) is regarded as a prominent alternative owing to the ideal bandgap and reduced toxicity exhibited by Sn-halide perovskites. …

Monumental Questions And How We Honor Them, Melynda J. Price

Kentucky Law Journal

No abstract provided.

Hyperreal: Law And The Interpretation Of Visual Media, Amy L. Landers

Kentucky Law Journal

No abstract provided.

The Midsession Reversal Task With Pigeons: Effects Of A Brief Delay Between Choice And Reinforcement, Megan Ashley Halloran

Theses and Dissertations--Psychology

During a midsession reversal task, the session begins with a simple simultaneous discrimination in which one stimulus (S1) is correct and the alternate stimulus (S2) is incorrect (S1+/S2-). At the halfway point, the discrimination reverses and S2 becomes the correct choice (S2+/S1-). When choosing optimally, a pigeon should choose S1 until the first trial in which it is not reinforced and then shift to S2 (win-stay/lose-shift). With this task pigeons have been shown to respond suboptimally by anticipating the reversal (anticipatory errors) and continuing to choose S1 after the reversal (perseverative errors). This suboptimal behavior may result from a pigeon’s …

Elementary School Children’S Understanding Of Disproportionate Discipline, Sharla D. Biefeld

Theses and Dissertations--Psychology

In the U.S. Black students, particularly Black boys, receive more out of school punishments, are punished more frequently, and are punished for more subjective behaviors than their White peers (Skiba, Michael, Nardo, & Peterson, 2002). This phenomenon is referred to as disproportionate discipline and is an early precursor to the disproportionate number of Black men and boys incarcerated in the U.S. Disproportionate discipline begins as early as preschool, and continues throughout elementary, middle, and high school (Gregory & Fergus, 2017). Perceptions of discrimination greatly impact children’s school involvement, school belonging, and educational outcomes (Brown, 2017, for review). However, little is …

Attentional Control In Infancy: The Role Of Sociodemographic Risk, Cortisol, And The Home Environment, Hannah B. White

Theses and Dissertations--Psychology

Infants’ ability to channel their cognitive resources by controlling their visual attention allows them to be active agents in their learning and development. Individual differences in attentional control have been linked to a wide variety of developmental outcomes including disparities between social classes in cognitive functioning. However, it is yet unknown when in development differences in attentional control related to sociodemographic factors emerge, or how factors of the home environment and the infant’s stress response relate to this effect. Accordingly, Experiment 1 examined whether certain sociodemographic factors, such as socioeconomic and minority status, predict 3.5-month-old infants’ (N = 102) …

Ethanol Sustains Phosphorylated Tau Protein Immunofluorescence In The Cultured Neonatal Rat Hippocampus: Implications For Fetal Alcohol Spectrum Disorders, Caleb Seth Bailey

Theses and Dissertations--Psychology

Fetal Alcohol Spectrum Disorders (FASDs) are comprised of developmental, behavioral, and cognitive abnormalities caused by prenatal alcohol exposure, affecting an estimated 2%-5% of childrenand costing up to $4 billion annually in the United States alone. Although some behavioral therapies can help, the biochemical mechanisms that underpin FASDs need further elucidation for development of more efficacious therapeutics. The tau protein modulates cytoskeletal structure in neurons, and thereby plays an integral role in proper development and function of the central nervous system, but its function is altered by its phosphorylation state, such that increased phosphorylation reduces tau protein function. The tau protein …

Escalation And Reinstatement Of Fentanyl Self-Administration In Male And Female Rats, Samantha G. Malone

Theses and Dissertations--Psychology

Escalation of intake and craving are two DSM-5 hallmark symptoms of opioid use disorder (OUD). Objectives: This study determined if escalation measured by long access (LgA) self-administration and craving measured by reinstatement are related. Adult male and female Sprague-Dawley rats were trained to self-administer (SA) fentanyl across 7 daily 1-h sessions, followed by 21 SA sessions of either 1- or 6-h duration. Assignment to short access (ShA) and long access (LgA) groups was randomly determined for both males and females. Following 14 1-h extinction sessions, Experiment 1 assessed reinstatement induced by either fentanyl (10 or 30 μg/kg) or yohimbine (1 …

Village-Temple Consciousness In Two Jaffna Tamil Villages In Post-War Sri Lanka, Pathmanesan Sanmugeswaran

Theses and Dissertations--Anthropology

This dissertation investigates how community rebuilding is occurring in a gravely damaged, post-conflict society. Specifically, it looks at how people in two villages in Tamil, Hindu, Jaffna, Sri Lanka, are using their ‘sense of place’ and ‘place-making practices’ or what I call here their ‘village-temple consciousness’ or village consciousness, to maintain and rebuild their communities after war to make them, once again, places in which they feel a comfortable sense of belonging. This is a comparative study because Inuvil and Naguleswaram were affected differently by the Sri Lankan civil war. That is, while Inuvil, was physically damaged and socially disrupted …

Application Of High Performance Training Strategies To Enhance Occupational Readiness In Law Enforcement Cadets, Gabriel Jose Martinez

Theses and Dissertations--Kinesiology and Health Promotion

Law enforcement requires cadets to achieve a requisite level of physical fitness to prepare for occupational demands. However, there is limited research on the effectiveness of academy exercise programs to optimize physical fitness and occupational physical ability through high performance training strategies more typically utilized in elite athletic populations. Furthermore, there is a paucity of research identifying physical fitness correlates of occupational performance. Collectively, this information will provide academies and practitioners with critical information to develop evidence-based training programs. Therefore, the purposes of this study were to: Aim 1) Examine the effectiveness of integrating autoregulatory progressive resistance exercise (APRE) and …

Instructional Strategies Manual, 4th Edition: For The Helpful Entry Level Skills Checklist, 4th Edition, Beth S. Rous

Educational Leadership Studies Faculty Publications

The Instructional Strategies Manual, 4th Edition is a companion resource for the Helpful Entry Level Skills Checklist. The manual provides teachers, families, and early childhood teams with strategies, activities, and adaptations to support young children’s development of social, behavioral, communication, classroom, work, and self-management skills during the transition from preschool to school-age programs. The manual is organized around five major skill areas: classroom rules, work skills, communication skills, social behavior skills, and self-management skills. It includes strategies that can be embedded into daily classroom routines, family activities, and individualized supports, with adaptations for children with hearing, vision, cognitive, physical, speech/language, …

Can Precision Farming Technologies Be Applied To Grazing Management?, S. Mark Rutter

IGC Proceedings (1977-2023)

In arable farming, precision is used to monitor and manage crop variability. The same precision approach can be used to manage grassland, by using crop sensing, targeted fertilizer/herbicide/pesticide application and forage yield measurement when it is harvested mechanically. An additional challenge in grassland agriculture is developing precision approaches to manage the grazing process. This requires technologies to determine where an animal is, when, what and how much it is grazing which the system then needs to use in conjunction with other sources of information to control where the animal grazes next. This paper reviews the existing technologies in these …

Manipulation Of The Spatial Grazing Behaviour Of Livestock In Extensive Grassland Systems, Derek W. Bailey, Mitch B. Stephenson, Milton G. Thomas, Juan F. Medrano, Gonzalo Rincon

IGC Proceedings (1977-2023)

Spatial behaviour of livestock is a critical factor in grassland management. Recent and ongoing research suggests that new approaches can be used to manipulate where cattle graze. The combination of strategic supplement placement and low-stress herding can be used to target cattle grazing and potentially may be useful for managing fine fuels. A phenotype to genotype association study of cattle spatial behavior suggests that use of rugged terrain and areas far from water is inherited. Although more research is needed, selection for animals specifically adapted for mountainous terrain or extensive paddocks may be an alternative for managing grasslands in the …

Opportunities For Improving Livestock Production With E-Management Systems, Dave L. Swain, Rebecca N. Handcock, Greg J. Bishop-Hurley, Don Menzies

IGC Proceedings (1977-2023)

There is increased interest in hardware and software that can support e-Management for grassland-based livestock industries. Managers of grazing livestock were early adopters of radio frequency identification (RFID) technologies automatically monitoring individual animal performance. Recent developments of remote sensing, automated individual recording and management, location based systems, improved data transfer and technologies that can be used in more extensive grazing systems are providing new opportunities for the development of e-Management systems. There is a need for better data integration and systems that can provide the best available information to enable better decision-making. For greater industry adoption of more integrated e-Management …

Growth Of Bali Bulls Fattened With Forage Tree Legumes In Eastern Indonesia: Leucaena Leucocephala In Sumbawa, Tanda Panjaitan, Muhammad Fauzan, H. Dahlanuddin, Michael J. Halliday, H. Max Shelton

IGC Proceedings (1977-2023)

The contribution of West Nusa Tenggara Province to domestic beef supply in Indonesia is relatively small, however, beef cattle are very important for the livelihoods of smallholder farmers in the region.

Bali cattle (Boss javanicus) are the predominant breed as they are adapted to harsh nutritional conditions, are highly fertile and have low calf mortality (Toelihere 2003). While genetically capable of achieving a growth rate of 0.85 kg/d (Mastika 2003), Panjaitan (2012) identified poor nutrition as a severe limitation to animal growth in traditional village systems. Improving feed quality and supply is vital to increasing growth rates and …

Effect Of High Se And Co Alfalfa Forage On Animal Production, Xiao-Lei Jie, Xiao Guo, Hua-Feng Hu

IGC Proceedings (1977-2023)

Total and available selenium (Se) and cobalt (Co) concentrations are low in Chinese soils, especially those found in mainly in temperate humid sub-humid conditions in the northeast to the southwest band across China (Tan et al. 2002). The levels of Se and Co are marginally deficit in the brown soil of the Yellow River region which causes lower production level and quality in forage and crop plants. Application of Se and Co fertilizers to arable lands is essential to produce high Se and Co forages. Henan is a Province where produce high-quality grass forages are used to support dairy …

Performance, Carcass Characteristics And Meat Quality Of Grazing Lambs Finished On Tropical Grasses, Cesar H. E. C. Poli, Samuel Carnesella, Fernando M. Souza, Concepta Mcmanus, Zélia M. S. Castilhos, Liris Kindlein, Jaime U. Tarouco

IGC Proceedings (1977-2023)

Brazil is a country of continental size, and more than seven million ha are occupied with tropical pasture. Worldwide animal production from tropical pastures is also very significant where Cynodon, Panicum and Paspalum are important genus. These grasses are widely used in the production of cattle, and are growing in importance for sheep production, but their potential for producing quality lamb is not fully known.

The objective of this study was to evaluate the potential of two tropical grasses for finishing lambs in autumn to reduce the seasonality of production of lamb for meat.

Alternative Pasture Development System And Breeding Weight For Beef Heifers, H. A. Lardner, Daalkhaijav Damiran, Steve Hendrick, Kathy Larson

IGC Proceedings (1977-2023)

Proper development of replacement beef heifers is critical and needs to be accomplished at lower costs without sacrificing reproductive performance. The current recommendations indicate heifers should reach approximately 65% of mature body weight (MBW) at breeding for successful reproduction (Patterson et al. 1992; NRC 1996). Meeting heifer maintenance and gestation nutrient requirements are getting more economically challenged for beef producers in western Canada. Therefore, producers are moving from drylot development systems where cattle are housed and fed in pens to the adoption of extensive grazing systems (Kelln et al. 2011) in field paddocks. Limited research has been conducted …

Variation Of Rumen Bacterial Diversity In Steers After The Beginning Of Grazing, Miwa Nakano, Satoshi Haga, Masanori Tohno, Kazuhiro Matoba, Ryuichi Uegaki, Hiroshi Ishizaki

IGC Proceedings (1977-2023)

Holstein heifers before or after puberty often are herded on public pastures in Japan. The herbage intake and rumen fermentation of grazing heifers that are not adapted for fresh herbage decreases due to a change of feed from stall-fed dried forage to fresh herbage. This limits their performance during the first several weeks on pasture. Thus, the feeding program such as supplementation before and after the beginning of grazing is important. An increase in ammonia concentration and a decline in fibre degradation in the rumen of a heifer (both of which occur simultaneously with low herbage intake and rumen fermentation) …

Forage Systems Effect On Forage-Fed Beef Production, Guillermo Scaglia, Basu Bhandari, Jeffrey M. Gillespie, Jim J. Wang

IGC Proceedings (1977-2023)

Locally produced forage-finished beef offers high value while enhancing economic, environmental, and social sustainability. It enhances environmental quality and the natural resource base, and makes good use of resources both on and off-farm. On the farm, it makes the most of the ability of cattle to convert grass to meat in a low-input system, making efficient use of solar energy, improving soil nutrient cycling, conserving soil and water, and limiting reliance on non-renewable resources (DeRamus 2004). Although the major causes of increased greenhouse gas emissions are due to population growth and industrialization, agriculture contributes to carbon dioxide (CO2) emissions through …

Activity, Physiology And Milk Production Of Yaks And Two Different Yak Crossbreds Grazing Himalayan Pasture Sites At 4700 M And 3000 M, Shanker R. Barsila, Naba R. Devkota, Michael Kreuzer, Svenja Marquardt

IGC Proceedings (1977-2023)

Yaks (Bos grunniens) and crossbreds of yaks with different local cattle breeds are important for the livelihood of local herders in the Himalayas. They are often kept in a system of transhumance comprising the use of different pasture sites for grazing along an altitudinal gradient throughout the year. The animals are moved upwards to the high altitude pastures in spring/early summer and gradually moved downwards in late summer/autumn. Yaks are suitable for very high altitudes as they are especially adapted to low oxygen partial pressure, forage scarcity and cold and harsh environment (Wiener et al. 2003). However, …