Digital Commons Network^™

Using Geospatial Information Technologies To Identify Factors Affecting Grazing Distribution On Grasslands, W. H. Schacht, A. Guru, P. E. Reece, J. D. Volesky, D. C. Cotton

IGC Proceedings (1977-2023)

The relationship between environmental and management factors and grazing livestock distribution is fundamental to understanding and improving grazing systems. With the advent of geospatial information technologies, global positioning systems (GPS) and geographic information systems (GIS) have been used to improve the efficiency and effectiveness of quantifying the distribution of livestock grazing in response to various independent variables (Bailey et al., 2001). The specific objective of this project was to develop a tool that enables managers and students to identify and study the effect of management and environmental factors on grazing livestock distribution.

The Use Of Digital Imagery For The Assessment Of Green Biomass In Native Pastures, A. F. Southwell, G. Mckenzie, James M. Virgona, A. M. Ridley, P. Ederback

IGC Proceedings (1977-2023)

A practice common to pasture research is the assessment of green leaf. In Australia, where the water use of plants is becoming an increasingly important issue due largely to its implications for dryland salinity, it is imperative that accurate and repeatable methods for characterising the amount of green leaf in pastures be used. The assessment of green leaf has been approached in many ways in the past with varying degrees of success and accuracy. The most accurate way is to physically harvest an area of pasture and separate the green component to make the relevant measurements. For many situations, this …

The Role Of Proper Use Factor Model For The Prediction Of Available Forage In Rangeland In The South Of Iran, G. R. Badjian, I. Dahlan, M. Shahwahid H. O., A. A. Mehrabi

IGC Proceedings (1977-2023)

In Iran, 80 to 90% of the livestock production is associated with rangeland but 48% of the rangeland has been classified as in poor condition (Farahpour, 2002). Available Forage (AF) is that portion of the forage production accessible for use by a specified kind or class of grazing animal. Estimates of AF by plant species, consumption by the animal, and the contribution of the forage to the animal's diet must be synchronised with each other in the same time frame (Valentine, 2001). The Proper Use Factor (PUF) is the degree of utilisation of current year's growth of the vegetation that, …

Assessment And Monitoring Of Grazing Lands In The Northeastern United States, M. A. Sanderson, Sarah C. Goslee, J. B. Cropper, R. B. Bryant

IGC Proceedings (1977-2023)

The Pasture Condition Score System (Cosgrove et al., 2001) was developed as a monitoring and management tool on grazing lands The system considers 10 indicators of soils, plants, and animals including percent desirable plants, plant cover, plant diversity, plant residue, plant vigor, percent legume, uniformity of use, livestock concentration areas, soil compaction, and soil erosion. The indicators are assigned a score according to detailed criteria and the scores are summed to give an overall score for a pasture, or relevant grazing unit. The score is then interpreted, indicating if some type of management change or treatment is necessary. We …

On-Farm Information: A Valuable Tool For The Sustainable Management Of Mountain Pastures In Protected Natural Areas, N. Mandaluniz, A. Bernués, A. Igarzabal, I. J. L. Riedel, R. Ruiz, A. Sanz, I. Casasús, L. M. Oregui

IGC Proceedings (1977-2023)

Mountain pastures have traditionally been maintained by livestock. The analysis of data concerning farms' characteristics, productive-reproductive management and land use of commercial farms can constitute a real approach to study these systems and the changes that are occurring. This information is necessary to develop new utilisation guidelines, making compatible livestock production and conservation of natural resources. This paper describes a methodological framework to study the issues described above through some examples taken out from a wider research project (Mandaluniz et al., 2003).

Disappearance Of Residual Dry Matter On Annual Grassland In The Absence Of Grazing, W. E. Frost, J. W. Bartolome, K. R. Churches

IGC Proceedings (1977-2023)

Residual dry matter (RDM) is a standard used by grassland managers for assessing the level of grazing use on annual grasslands and associated savannas and woodlands. Residual dry matter is the old plant material left standing or on the ground at the beginning of a new growing season. It indicates the combined effects of the previous season's forage production and its consumption by grazing animals of all types. The standard assumes that the amount of RDM remaining in the fall, subject to site conditions and variations in weather, will influence subsequent species composition and forage production, in addition to providing …

The Impact Of Concentrate Price On The Utilization Of Grazed And Conserved Grass, P. Crosson, P. O'Kiely, F. P. O'Mara, M. J. Drennan, M. Wallace

IGC Proceedings (1977-2023)

A linear programming model was designed and constructed to facilitate the identification of optimal beef production systems under varying technical and policy scenarios. The model operates at a systems level and most activities that could occur in Irish spring-calving, suckler beef production systems are included. In this paper, the components of the model are described together with a simple application of the model involving changing concentrate prices.

Pâtur’In: A User-Friendly Software Tool To Assist Dairy Cow Grazing Management, Luc Delaby, J. L. Peyraud, P. Faverdin

IGC Proceedings (1977-2023)

The feeding of dairy cows at pasture presents many technical, economic and environmental advantages, while benefiting from a very favourable image. However, the management of grazed land is a complex game of strategy in which the farmer applies decisions in order to manage two unstable and uncertain fluxes of change: growth of grass and intake of the herd. Many tools (platemeter, etc.) and overall methods (local stocking rate references, farm cover, etc.) have been developed as aids to grazing management. Nevertheless, few decision-support systems are currently available that make it possible to anticipate and assess the consequences of a given …

External Validation In Northwest Spain Of A Decision Support System For Grazing Dairy Cows (Grazemore), Antonio González-Rodríguez, J. López Díaz, O. P. Vázquez Yáñez

IGC Proceedings (1977-2023)

A model to predict intake and milk production of cows on grazed grass (Grazemore) was developed (Mayne et al., 2004) for farmers to increase reliance on the grassland resources of the farm and reduce the tendency towards intensive dairy production in most countries of the Atlantic Arc of Europe (González, 2003). Climatic conditions and fertiliser use is the basis of the herbage growth model, but under practical conditions the estimation of the nutrient supply to cows is much affected by management, number of cows and the area of each paddock grazed. The intake capacity of the animal and the …

Allocating Grazing Resources With Kansasgrazer® And Making Management Decisions In A Stocker Operation, Joseph L. Moyer, J. O. Fritz

IGC Proceedings (1977-2023)

Management decisions for forage-beef cattle production systems are complex because of the many interrelated factors in the plant-animal complex. Evaluation of a system and effects of any changes to it are critical, however, because of the impact that any factor may have on the operation. A computer program to evaluate forage-beef cattle systems would enable producers to make more informed management decisions. Several such programs are available in Kansas, but they are not widely used because of their limited scope, user-friendliness and/or flexibility. Thus, an earlier program derived from the KYBEEF model by Bullock et al. (1983) was modified …

Enhancing Grasslands Education With Decision Support Tools, Helen G. Daily, J. M. Scott, J. M. Reid

IGC Proceedings (1977-2023)

We have successfully used Decision Support Tools (DST) relevant to the management of grazing enterprises to enhance problem solving skills of undergraduates in Australia. Tools such as GrassGro^tm (Moore et al., 1997) and GrazFeed^tm (Freer et al., 1997) are accessed from a central server by authorised users at many widely dispersed Universities across Australia using remote access to thin-client technology via an Internet portal. This has been supplemented with training for lecturers. Experience in developing appropriate teaching and learning materials and the reliable delivery of simulation software to many clients has enhanced learning outcomes at tertiary …

Forecasting Forage Yields Using The Arima Model In Pastoral Areas Of East Africa, Robert J. Kaitho, J. W. Stuth, Jay Angerer, A. A. Jama

IGC Proceedings (1977-2023)

Predicting forage supply is an age old quest for pastoralists, particularly in fragile and drought- prone areas of Africa. Traditional methods of forecasting forage used by many communities have become less effective due to climate change, frequent droughts and decline of grazing areas. Conflicts relating to available forage and water resources are increasing, because more marginal lands are put to crop production. A new forage forecasting technology has been developed that provides a comprehensive view of current forage condition (Stuth et al., 2004). A multiple species grazing land plant growth hydrology based model (PHYGROW) was parameterised with site-specific soil, …

A Model To Evaluate Buying And Selling Policies For Growing Lambs On Pasture, P. C. H. Morel, B. Wildbore, I. M. Brookes, Paul R. Kenyon, R. W. Purchas, S. Ramaswami

IGC Proceedings (1977-2023)

In pastoral sheep finishing systems, farmers aim to maximize profitability by deciding on when and how many animals to buy and/or sell, while taking into account feed availability and current prices. This paper describes a stochastic lamb growth simulation model with a set of heuristic rules, which has been developed to financially evaluate different management strategies for growing lambs on pasture.

An Internet-Based Tool For Use In Assessing The Likely Effect Of Intensification On Losses Of Nitrogen To The Environment, N. J. Hutchings, B. M. Petersen, I. S. Kristensen, N. Detlefsen, M. S. Jørgensen

IGC Proceedings (1977-2023)

The EU Nitrates, Habitat and National Emissions Ceilings directives and the Kyoto Agreement mean that agricultural losses of NO₃, NH₃ and N₂O are under scrutiny by national and international environmental authorities. When farmers wish to intensify their operations, the authorities must then assess the likely environmental impact of the change in operation. The FARM-N internet tool was developed to help farmers and authorities agree how the farm will be structured and managed in the future, and to provide an objective assessment of the environmental losses that will result.

N-Mineralisation And Phosphorous: Important Elements In Decision Support For Grassland Systems, A. Lisbeth Nielsen, C. C. Hoffmann

IGC Proceedings (1977-2023)

Leaching of N and P from extensively managed grasslands on organic soils varies considerably. In environmentally sensitive areas it is important to diminish leaching by appropriate agricultural management. In Denmark low grazing intensity and management without fertilisation have been given a high priority. The type of soil has not been equally in focus, and it seems that the effect of cutting, compared to grazing, resulting in a higher removal of nutrients (e.g. Benke et al., 1992) can be used more strategically. The objective of this case study was to combine data from management strategies with data from leaching examinations …

Artturi Assists Finnish Advisers And Farmers To Succeed In Grass-Based Dairy Production, Marketta Rinne, Pekka Huhtanen, Kaisa Kuoppala, H. Nikander, J. Nousiainen, M. Hellämäki, L. Nyholm, J. Helminen, K. Lampinen, M. Maisi, M. Korhonen

IGC Proceedings (1977-2023)

Artturi is a collective name for a wide range of services. It is a common tool for different bodies who share an interest in strengthening grass-based dairy production in Finland: research, advisory service and industries. The Service is named after A. I. (Artturi Ilmari) Virtanen, the Finnish scientist who was awarded the Nobel prize in 1945, partly based on his work in developing the ensiling process of grass. The Artturi web site is available in Internet at: http://www.agronet.fi/artturi. Access to Artturi Services is free and no registration is required. The language used is Finnish. During summer 2003, 15,000 visits were …

Involvement Of Maasai Pastoralists In Participatory Rangeland Management Planning And Implementation, Evelyne Kiptot, W, Ego, D. Ochieng, A. Mohamed

IGC Proceedings (1977-2023)

The pastoral Maasai lifestyle was and still is traditionally based on subsistence dairy and meat production. But with population increase, the rangelands can no longer sustainably support livestock production systems. Most of the rangelands which are used for grazing have been subdivided and partially cleared to pave way for cultivation, because of increased population pressure (Ego et al., 1999). This has led to a tendency to overgraze, thus impacting negatively on secondary production from the range. In order to effectively reverse this trend, the users of the rangeland resources were brought together to analyse constraints and opportunities for sustainable …

Management Of Pasture Quality For Sheep On New Zealand Hill Country, D. I. Gray, J. I. Reid, P. D. Kemp, I. M. Brookes, D. Horne, Paul R. Kenyon, C. Matthew, S. T. Morris, I. Valentine

IGC Proceedings (1977-2023)

The control of pasture quality over spring is central to the achievement of high levels of sheep performance on hill country. Despite this, with the exception of the work of Lambert et al. (2000), little is known about how farmers actually manage pasture quality. The purpose of this research was to describe how a high performing hill country farmer manages pasture quality on their sheep area over spring and from this develop a framework that will assist other farmers improve their pasture management.

Decision Support System For Grassland-Based Sheep Production In The Chilean Patagonia, R. R. Vera, S. Morales, C. Aguilar

IGC Proceedings (1977-2023)

Temporal decision-making in sheep production systems of the Chilean Patagonia is influenced by forage availability in existing paddocks, which in turn is determined by previous use, localisation, climate and soil. Also, production strategies are evolving, with a trend towards fat lamb production, introduction of new breeds and a reduction in the importance of wool production. The objective of this study was to develop an initial version of a spatial empirical simulation model based on extremely limited information, to predict forage growth and sheep production so that decision-makers can assess alternative production strategies.

A Decision Support System For Monitoring Livestock Diet Quality And Performance: Verification Study On Cattle, Adami Tulu, Ethiopia, A. A. Jama, G. Tolleson, J. W. Stuth, Abule Ebro, K. Zander, Robert J. Kaitho

IGC Proceedings (1977-2023)

Fecal profiling technology based on near infrared spectroscopy (NIRS) has been widely used in the U.S. to predict the diet quality and performance of free-ranging animals (e.g. Leite & Stuth 1995, Lyons & Stuth 1992, Lyons et al., 1993, Stuth et al., 1999, Tolleson et al., 2001). This technology is linked with the Nutritional Balance Analyzer (NUTBAL-PRO) model to form the core of a nutritional advisory system for livestock producers in the United States. This model predicts changes in body weight and condition for a broad range of livestock classes for cattle, sheep and goats. To test …

Irish Grassland Association: Delivering The Benefits From Grassland, S. Flanagan

IGC Proceedings (1977-2023)

The Irish Grassland Association (IGA) is Ireland's leading forum for discussing the science of grass and animal production, the economics and finances of dairy, beef cattle and sheep farm enterprises. Membership is 800 and is a lively mix of progressive farmers (70%), research scientists, advisers and agribusiness personnel. The IGA is a member of the European Grassland Federation and has close ties with the Ulster Grassland Society, Fermanagh Grassland Club and the British Grassland Society.

Activation Of The Renin–Angiotensin–Aldosterone System Is Attenuated In Hypertensive Compared With Normotensive Pregnancy, Robin C. Shoemaker, Marko Poglitsch, Hong Huang, Katherine Vignes, Aarthi Srinivasan, Cynthia Cockerham-Morris, Aric Schadler, John Anthony Bauer, John O'Brien

UK CARES Faculty Publications

Hypertension during pregnancy increases the risk of adverse maternal and fetal outcomes, but the mechanisms of pregnancy hypertension are not precisely understood. Elevated plasma renin activity and aldosterone concentrations play an important role in the normal physiologic adaptation to pregnancy. These effectors are reduced in patients with pregnancy hypertension, creating an opportunity to define the features of the renin–angiotensin–aldosterone system (RAAS) that are characteristic of this disorder. In the current study, we used a novel LC-MS/MS-based methodology to develop comprehensive profiles of RAAS peptides and effectors over gestation in a cohort of 74 pregnant women followed prospectively for the development …

Histamine Excretion In Common Indoor And Hematophagous Arthropods, Simona Principato, Alvaro Romero, Chow-Yang Lee, Kathleen Campbell, Dong-Hwan Choe, Coby Schal, Zachary C. Devries

UK CARES Faculty Publications

Histamine is a biogenic amine that regulates multiple physiological functions in diverse organisms, specifically playing a central role in the mammalian immune response. The common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), excretes histamine in large amounts in its feces as a component of its aggregation pheromone, which contaminates homes. The potential health risks associated with the presence of indoor histamine are unclear, but to predict future exposure risks, it is critical that we understand if other arthropods excrete histamine in any discernible phylogenetic pattern. In the present study, we evaluated histamine excretion by various arthropods; specifically those commonly found …

Functional Exploration Of Conserved Sequences In The Distal Face Of Angiotensinogen - Brief Report, Naofumi Amioka, Chia-Hua Wu, Hisashi Sawada, Sohei Ito, Alex C. Pettey, Congqing Wu, Jessica J. Moorleghen, Deborah A. Howatt, Gregory A. Graf, Craig W. Vander Kooi, Alan Daugherty, Hong S. Lu

Saha Cardiovascular Research Center Faculty Publications

BACKGROUND: Angiotensinogen (AGT) is an essential component in the renin-angiotensin system. AGT has highly conserved sequences in the loop and β-sheet regions among species; however, their functions have not been studied.

METHODS: Adeno-associated viral vector (AAV) serotype 2/8 encoding mouse AGT with mutations of conserved sequences in the loop (AAV.loop-Mut), β-sheet (AAV.βsheet-Mut), or both regions (AAV.loop/βsheet-Mut) was injected into male hepatocyte-specific AGT-deficient (hepAGT−/− ) mice in an LDL (low-density lipoprotein) receptor–deficient background. AAV containing mouse wild-type AGT (AAV.mAGT) or a null vector (AAV.null) were used as controls. Two weeks after AAV administration, all mice were fed a western diet for …

Asparagine Restriction Enhances Cd8+ T Cell Metabolic Fitness And Antitumoral Functionality Through An Nrf2-Dependent Stress Response, J. N. Rashida Gnanaprakasam, Bhavana Kushwaha, Lingling Liu, Xuyong Chen, Siwen Kang, Tingting Wang, Teresa A. Cassel, Christopher M. Adams, Richard M. Higashi, David A. Scott, Gang Xin, Zihai Li, Jun Yang, Andrew N. Lane, Teresa Whei-Mei Fan, Ji Zhang, Ruoning Wang

Markey Cancer Center Faculty Publications

Robust and effective T cell immune surveillance and cancer immunotherapy require proper allocation of metabolic resources to sustain energetically costly processes, including growth and cytokine production. Here, we show that asparagine (Asn) restriction on CD8+ T cells exerted opposing effects during activation (early phase) and differentiation (late phase) following T cell activation. Asn restriction suppressed activation and cell cycle entry in the early phase while rapidly engaging the nuclear factor erythroid 2-related factor 2 (NRF2)-dependent stress response, conferring robust proliferation and effector function on CD8+ T cells during differentiation. Mechanistically, NRF2 activation in CD8+ T cells conferred by Asn restriction …

Co-Targeting Nucleus Accumbens Associate 1 And Nf-Κb Signaling Synergistically Inhibits Melanoma Growth, Lixiang Gu, Xingcong Ren, Chrispus Ngule, Xiaofang Xiong, Jianxun Song, Zhiguo Li, Jin-Ming Yang

Markey Cancer Center Faculty Publications

Nucleus-accumbens-associated protein-1 (NAC1) is a cancer-related transcriptional factor encoded by the NACC1 gene, which is amplified and overexpressed in various human cancers and has been appreciated as one of the top potential cancer driver genes. NAC1 has therefore been explored as a potential therapeutic target for managing malignant tumors. Here, we show that NAC1 is a negative regulator of NF-κB signaling, and NAC1 depletion enhances the level of the nuclear NF-κB in human melanoma. Furthermore, the inhibition of NF-κB signaling significantly potentiates the antineoplastic activity of the NAC1 inhibition in both the cultured melanoma cells and xenograft tumors. This study …

Identification Of Immunodominant T Cell Epitopes Induced By Natural Zika Virus Infection, Christopher S. Eickhoff, Krystal A. Meza, Frances E. Terry, Chase G. Colbert, Azra Blazevic, Andres H. Gutiérrez, E. Taylor Stone, James D. Brien, Amelia K. Pinto, Hana M. El Sahly, Mark J. Mulligan, Nadine Rouphael, Maria L. Alcaide, Kay M. Tomashek, Chris Focht, William D. Martin, Leonard Moise, Anne S. De Groot, Daniel F. Hoft

Markey Cancer Center Faculty Publications

Zika virus (ZIKV) is a flavivirus primarily transmitted by Aedes species mosquitoes, first discovered in Africa in 1947, that disseminated through Southeast Asia and the Pacific Islands in the 2000s. The first ZIKV infections in the Americas were identified in 2014, and infections exploded through populations in Brazil and other countries in 2015/16. ZIKV infection during pregnancy can cause severe brain and eye defects in offspring, and infection in adults has been associated with higher risks of Guillain-Barré syndrome. We initiated a study to describe the natural history of Zika (the disease) and the immune response to infection, for which …

Identification Of Monotonically Expressed Long Non-Coding Rna Signatures For Breast Cancer Using Variational Autoencoders, Dongjiao Wang, Ling Gao, Xinliang Gao, Chi Wang, Suyan Tian

Markey Cancer Center Faculty Publications

As breast cancer is a multistage progression disease resulting from a genetic sequence of mutations, understanding the genes whose expression values increase or decrease monotonically across pathologic stages can provide insightful clues about how breast cancer initiates and advances. Utilizing variational autoencoder (VAE) networks in conjunction with traditional statistical testing, we successfully ascertain long non-coding RNAs (lncRNAs) that exhibit monotonically differential expression values in breast cancer. Subsequently, we validate that the identified lncRNAs really present monotonically changed patterns. The proposed procedure identified 248 monotonically decreasing expressed and 115 increasing expressed lncRNAs. They correspond to a total of 65 and 33 …

Portable Optical Spectroscopic Assay For Non-Destructive Measurement Of Key Metabolic Parameters On In Vitro Cancer Cells And Organotypic Fresh Tumor Slices, Jing Yan, Carlos Frederico Lima Goncalves, Madison O. Korfhage, Zahid Hasan, Teresa Whei-Mei Fan, Xiaoqin Wang, Caigang Zhu

Markey Cancer Center Faculty Publications

To enable non-destructive metabolic characterizations on in vitro cancer cells and organotypic tumor models for therapeutic studies in an easy-to-access way, we report a highly portable optical spectroscopic assay for simultaneous measurement of glucose uptake and mitochondrial function on various cancer models with high sensitivity. Well-established breast cancer cell lines (MCF-7 and MDA-MB-231) were used to validate the optical spectroscopic assay for metabolic characterizations, while fresh tumor samples harvested from both animals and human cancer patients were used to test the feasibility of our optical metabolic assay for non-destructive measurement of key metabolic parameters on organotypic tumor slices. Our optical …

The Role Of Vaccination Route With An Adenovirus-Vectored Vaccine In Protection, Viral Control, And Transmission In The Sars-Cov-2/K18-Hace2 Mouse Infection Model, Alexandria Dickson, Elizabeth Geerling, E. Taylor Stone, Mariah Hassert, Tara L. Steffen, Taneesh Makkena, Madeleine Smither, Katherine E. Schwetye, Jianfeng Zhang, Bertrand Georges, M. Scot Roberts, John J. Suschak, Amelia K. Pinto, James D. Brien

Markey Cancer Center Faculty Publications

Introduction: Vaccination is the most effective mechanism to prevent severe COVID-19. However, breakthrough infections and subsequent transmission of SARS-CoV-2 remain a significant problem. Intranasal vaccination has the potential to be more effective in preventing disease and limiting transmission between individuals as it induces potent responses at mucosal sites.

Methods: Utilizing a replication-deficient adenovirus serotype 5-vectored vaccine expressing the SARS-CoV-2 RBD (AdCOVID) in homozygous and heterozygous transgenic K18-hACE2, we investigated the impact of the route of administration on vaccine immunogenicity, SARS-CoV-2 transmission, and survival.

Results: Mice vaccinated with AdCOVID via the intramuscular or intranasal route and subsequently challenged with SARS-CoV-2 showed …