Digital Commons Network^™

Detection Of Morphine And Its Analogues Using Enzymatic Hydrolysis, Joan Combie, Jerry W. Blake, Thomas E. Nugent, Thomas Tobin

Veterinary Science Faculty Patents

The invention relates to a method for hydrolyzing drug glucuronic acid conjugates present in mammalian body fluids, the conjugates being derived from a narcotic analgesic, antagonist, or agonist-antagonist whose metabolism includes conjugation with glucuronic acid. The method comprises incubating the body fluid sample at from about 60 to about 70° C., for at least about 1 hour, with 3-glucuronidase derived from Patella vulgata, and substantially increases the sensitivity of chromatographic techniques for the detection of morphine and its analogues.

Jackson V. Virginia: Reopening The Pandora's Box Of The Legal Sufficiency Of Drug Identification Evidence, Edward J. Imwinkelried

Kentucky Law Journal

No abstract provided.

The Book Thieves Of Lexington: A Reminiscence, Thomas D. Clark

The Kentucky Review

No abstract provided.

Activation Of B Lymphocytes By Monovalent Anti-Lyb-2 Antibodies, Subbarao Bondada, D. E. Mosier

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Small resting B lymphocytes are activated when their cell surface immuno-globulin (Ig) receptors interact with specific antigen or anti-Ig antibodies. Such a receptor-ligand interaction leads to enlargement and proliferation of B lymphocytes. These activated B cells can subsequently mature into Ig-secreting cells in the presence of appropriate accessory cell signals (1-3). However, monovalent anti-Ig antibodies cannot induce B cell activation even though they can bind to the surface Ig (4-7). It has thus been concluded that membrane Ig has to be cross-linked to induce early steps in B cell activation (membrane depolarization; 8) as well as later steps (proliferation). T …

Liability And Responsibility Of Bank Directors: Being Alert To Troubled Times, Lawrence K. Banks, Paula S. Hoskins

Kentucky Law Journal

No abstract provided.

Zen And The Art Of Exemplary Damages Assessment, Theodore Emens Cowen

Kentucky Law Journal

No abstract provided.

Kentucky Law Survey: Evidence, Newton B. Fowler Iii

Kentucky Law Journal

No abstract provided.

Method For Improving The Metabolic Stability And Survival Of Neonatal Pigs, Tim S. Stahly

Animal and Food Sciences Faculty Patents

A method of improving the metabolic stability of neonatal pigs and increasing their survival rate by administering to the pregnant sow during its latter stages of gestation up to about 80 days prior to parturition an effective amount of a material selected from the group consisting of a dihydroxy alkanol having 3 to 10 carbon atoms; a triglyceride of glycerol and fatty acids wherein at least one of the fatty acid moieties containing 8 to 12 carbon atoms with the remaining acid moieties containing 13 to 20 carbon atoms; the mono and diol esters of said alkanols and said fatty …

"Mistral" And "Evangeline": The Gothic Derivation Of Absalom, Absalom!, Steven T. Ryan

The Kentucky Review

No abstract provided.

The Symbolic Structure Of Andrew Lytle's The Velvet Horn, Anne Foata

The Kentucky Review

No abstract provided.

The Red River Gorge: The Existence Of "Recreational Niches" And Their Management Implications, Sara E. Alexander, Billie R. Dewalt, Eugenie Scott

KWRRI Research Reports

Until the late 1960's, the Red River Gorge was just one of the more beautiful parts of the Daniel Boone National Forest. At this time, the Army Corps of Engineers proposed to dam the river for flood control, water supply, and recreation purposes. Intense opposition to the project generated considerable publicity and the Gorge area experienced substantial increases in visitation. The result has been not only severe environmental degradation but extensive overcrowding as well. These trends are presently overtaxing management capabilities of the United States Forest Service. The most pressing issue has come to be how to effectively manage this …

Nasal Dosage Forms Of Propranol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering propranolol, a known β-adrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further relates to novel dosage forms of propranolol which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.

Effect Of Nitrogen Fertilization On Fall Stockpiled Ky 31 Fescue, Kenneth L. Wells

Soil Science News and Views

Much interest has developed during the past several years on improving utilization of tall fescue by accumulating its growth during the fall and delaying grazing until late fall and winter. This technique takes advantages of the buildup of sugars in the herbage which normally takes place as seasonal temperatures cool to near the freezing point. UK forage research has shown that content of sugars in tall fescue herbage can increase from around 8 percent in late summer to around 20 percent after the first few frosts have occurred in late fall. This sugar buildup greatly increases the feed value of …

Modeling Surface And Subsurface Stormflow On Steeply-Sloping Forested Watersheds, Patrick G. Sloan, Ian D. Moore, George B. Coltharp, Joseph D. Eigel

KWRRI Research Reports

A simple conceptual rainfall-runoff model, based on the variable source area concept, was developed for predicting runoff from small, steep-sloped, forested Appalachian watersheds. Tests of the model showed that the predicted and observed daily discharges were in good agreement. The results demonstrate the ability of the model to simulate the "flashy" hydrologic behavior of these watersheds.

Five subsurface flow models were evaluated by application to existing data measured at Coweeta on a reconstructed homogeneous forest soil. The five models were: Nieber 's 2-D and 1-D finite element models (based on Richards' equation), the kinematic wave equation, and two simple storage …

Water Rights Legislation In The East: A Program For Reform, Richard C. Ausness

Law Faculty Scholarly Articles

Expanding municipal and Industrial demand, along with increasing use of supplemental irrigation have escalated consumptive water use dramatically In the Eastern United States since World War II. This escalated use already has caused water shortages in some parts of the East, and experts predict more widespread water supply problems In the future.

As the inadequacies of the common law water rights system in a water-scarce environment have become evident, many eastern states have supplemented or replaced common law rules with some form of statutory water allocation system. Typically, these statutes establish a permit system administered by a state water resources …

N:S Ratio Of Forages In Kentucky, Kenneth L. Wells

Agronomy Notes

Concern has been expressed during recent years that sulfur may have become more limiting for plant growth and subsequently ruminant animal nutrition than was expected. This likelihood is based largely on the fact that (a) the inherent sulfur content of fertilizer phosphates has greatly diminished with declining use of normal superphosphate in manufacture of mixed fertilizers, (b) increased regulatory effect on burning of high sulfur fuels, and (c) increased use of nitrogen fertilizers for production of animal feeds. Assumedly, any or all these factors could result in alteration of nitrogen and sulfur content of forages to the point that either …

The Induction Of Tolerance To Heavy Metals In Natural And Laboratory Populations Of Fish, Wesley J. Birge, William H. Benson, Jeffrey A. Black

KWRRI Research Reports

Aquatic toxicity studies were performed on two natural populations of fathead minnows. One group of organisms was taken from a metal-contaminated flyash pond associated with a coal-fired power plant and the other group was collected from relatively uncontaminated hatchery ponds. Acute tests indicated that flyash pond fish were significantly more tolerant to cadmium and copper than were hatchery fish. At an exposure concentration of 6.0 mg Cd/L in moderately hard water, the median period of survival for flyash pond fish was 50.0 hr compared to 6.8 hr for hatchery fish. Both groups of organisms were about equally sensitive to zinc. …

Effects Of Surface Application Of Dairy Manure On The Infiltration Rate And Quality Of Surface Runoff, Joseph L. Taraba, I. J. Ross, John D. Bottom, Bill J. Barfield

KWRRI Research Reports

Dairy manure was surface spread on 12 ft x 12 ft plots on an established fescue pasture in the summer and fall of 1981 and 1982. The soil was a Maury silt loam. A simulated rainfall was applied to plots to test the effects of nitrogen loading rate (75, 150, and 300 #N/acre) time delay between manure application and the simulated rainfall events (0, 3, 6, 24, 48, 96 hours and a 120 hour test repeated on 0 hr plot with 300 #N/acre), and type manure (semi-solid - 1981 and liquid - 1982) on the concentrations of pollutants in the …

Nasal Dosage Forms Containing Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering the natural female sex hormones, 17 β-estradiol and progesterone, to achieve enhanced bioavailability thereof. The invention further relates to novel dosage forms of 17 β-estradiol and/or progesterone which are adapted for nasal administration, such as solutions, suspensions, gels and ointments. The dosage forms containing a combination of 17 β-estradiol and progesterone are particularly useful as contraceptives, while the dosage forms containing only one of the hormonal components find utility in the treatment of conditions such as menopause, menstrual disorders, etc., which are known to respond to administration of a natural or …

College Of Law Commencement Program, 1983, University Of Kentucky

Graduation Programs

No abstract provided.

Performance Of Tall Fescue Varieties, Robert C. Buckner, Paul B. Burrus Ii, Nelson Gay, Garry D. Lacefield

Agronomy Notes

The objective of the tall fescue breeding program is the development of varieties characterized by superior nutritive value (including reduced contents of perloline and loline alkaloids and the fungal endophyte, Epichloe typhina), palatability, disease resistance, and adaptation through the utilization of intergeneric and interspecific hybrid derivatives of ryegrass and tall fescue species. Varieties previously released from the breeding program were, Kentucky 31, Kenwell, and Kenhy. Johnstone tall fescue, developed cooperatively by the Kentucky Agricultural Experiment Station and USDA-ARS, was released March 1, 1982, as,a new variety. Johnstone is characterized as having low levels of perloline alkaloid and the fungal endophyte, …

Hume And America, Donald Livingston

The Kentucky Review

No abstract provided.

Stephen Crane: Metropolitan Correspondent, Joseph Katz

The Kentucky Review

No abstract provided.

"As Exciting As Being In Hell": Maxim Gorky In The United States, Judith H. Mcdowell

The Kentucky Review

No abstract provided.

Weed Management In Alfalfa, William W. Witt

Kentucky Alfalfa and Stored Forage Conference

Weeds compete with alfalfa for water, nutrients, light, and space. This competition can decrease yields, lower forage quality, increase disease and insect problems, create harvesting problems, and initiate or poison the animals which will consume the forage. Premature loss of alfalfa stands is usually the result of the interaction of the pest complex - diseases, insects, and weeds.

Traffic Safety Analysis: University Of Kentucky Area, Kentucky Transportation Research Program

Kentucky Transportation Center Research Report

The concept of Transportation System Management (TSM) is based on the use of transportation facilities for the efficient and safe movement of people and goods. Through a grant administered by the U.S. Department of Transportation, the Lexington-Fayette Urban County Government contracted with the University of Kentucky (UK) to develop and implement a "Ridesharing Program" and a "Minor Traffic Control Improvements Program".

Discussions of the traffic safety problems around the University area by the Lexington-Fayette Urban County Council coincided with UK's initial work in the traffic safety portion of the grant. Following those discussions, a request was made by the Council …

Stephen Crane's Concept Of Death, Joseph Katz

The Kentucky Review

No abstract provided.

Limiting Swine Stress With Evaporative Cooling In The Southeast, Robert L. Fehr, K. T. Priddy, Samuel G. Mcneill, Douglas G. Overhults

Biosystems and Agricultural Engineering Faculty Publications

Three-hourly weather data for 7 locations in the Southeast and Central United States were used to evaluate the feasibility of evaporative cooling for reducing swine stress. Stress was defined as a relationship between dry and wet bulb temperatures which exceeded a stress index of 85. This analysis indicates that properly installed evaporative coolers could reduce the number of hours that stress would occur in swine facilities from 89.6 to 96.4% depending on location.

La Noche De Las Cien Cabezas And Noctumo De Los Catorce: Surrealistic Visions Of Ramon J. Sender, Beverly L. Richard

Ariel

No abstract provided.

A Dairy Cow Housing System Featuring Motel Free Stalls, Robert L. Fehr, William L. Crist

Agricultural Engineering Extension Updates

The term motel free stalls describes a milking cow housing system that utilizes roof area which protects only the free stalls. Alleys are only partially protected by the roof overhang. This system provides little protection from extreme temperatures but can provide some summer protection if properly constructed. Motel free stall systems reduce the initial cost of constructing lactating cow housing. Motel free stall system described in this paper should be used with caution in climatic regions colder than Kentucky because of limited protection from extreme cold temperatures. This paper describes the application of motel free stall housing systems and a …