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Kentucky Water Resources Research Institute Annual Technical Report Fy 2000, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY 2000 Annual Technical Report for Kentucky consolidates the reporting requirements of the Section 104(b) base grant and previous regional competitive grant awards in a single technical report that includes: 1) a synopsis of each ongoing research project and each project completed during the period, 2) a list of related reports published, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable achievements and awards during the year.

Kentucky Traffic Collision Facts 2001 Report, Kentucky Transportation Center, Kentucky State Police

Kentucky Transportation Center Research Report

KENTUCKY’S TRAFFIC COLLISION FACTS report for 2001 is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize data on traffic collisions for such purposes as will improve the traffic safety program in the Commonwealth. Data contained in this report are based solely on the observations …

Tax Expenditures, Social Justice And Civil Rights: Expanding The Scope Of Civil Rights Laws To Apply To Tax-Exempt Charities, David A. Brennen

Law Faculty Scholarly Articles

In recent years, courts have decided a number of cases in which private organizations discriminated against people based solely on their race, gender, sexual orientation, or other immutable traits. For example, in 2000, the Boy Scouts of America revoked a New Jersey man's membership in the Boy Scouts because he was gay. New Jersey's supreme court held that the Boy Scouts' action violated New Jersey's anti-discrimination law. Notwithstanding the state court's holding, the United States Supreme Court concluded that the First Amendment prevented any court from forcing the Boy Scouts to keep a gay man as a member of its …

Introduction: From Sheet Music To Mp3 Files—A Brief Perspective On Napster, Harold R. Weinberg

Law Faculty Scholarly Articles

The Napster case is the current cause celebre of the digital age. The story has color. It involves music-sharing technology invented by an eighteen-year-old college dropout whose high school classmates nicknamed him "The Napster" on account of his perpetually kinky hair. The story has drama. Depending on your perspective, it pits rapacious big music companies against poor and hardworking students who just want to enjoy some tunes; or it pits creative and industrious music companies seeking a fair return on their invested effort, time, and money against greedy and irreverent music thieves. And the case has importance. Music maybe intellectual …

Impact Of Season And Heat Stress On Somatic Cell Counts, Brent A. Broaddus

University of Kentucky Master's Theses

Infection data were obtained monthly from June, 1999 to September, 2000 at the University ofKentucky dairy. Quarter foremilk samples were collected for bacteriological determination andsomatic cell counts (SCC). The Livestock Stress Index (LSI) estimated heat stress and is calculatedby combination of temperature and humidity. For uninfected quarters the geometric mean SCC was29,000 cells/ml. For infected quarters the geometric mean SCC was 213,000 cells/ml. Coagulasenegativestaphylococci (CNS) infections comprised 61 percent of the total infected quarters with ageometric mean SCC of 155,000 cells/ml. Staphylococcus aureus infected quarters had a geometricmean SCC of 680,000 cells/ml. There were no significant correlations between log SCC …

Diversity In Hunter-Gatherer Landscapes In The North American Midcontinent, Victor Dominic Thompson

University of Kentucky Master's Theses

The thesis examines changes in hunter-gatherer land-use along lower Cypress Creek, atributary of the Green River located in west-central Kentucky. Presented, are the results of the firstthree years of site survey and museum work conducted by the Cypress Creek Archaeological Project.Analysis of site location and hafted bifaces suggests that, throughout the Holocene, increasingemphasis was placed on certain locations and areas of the landscape. Comparison of the CypressCreek study area with other areas of Archaic research indicate that land-use was highly variable inboth space and time across the North American midcontinent.

Does Apprendi V. New Jersey Change The Standard Of Proof In Criminal Forfeiture Cases?, Stefan D. Cassella

Kentucky Law Journal

No abstract provided.

A "Clanging Silence": Same-Sex Couples And Tort Law, John G. Culhane

Kentucky Law Journal

No abstract provided.

Currents In The Stream: The Evolving Legal Status Of Gay And Lesbian Persons In Kentucky, Matthew M. Morrison

Kentucky Law Journal

No abstract provided.

Pharmaceutical Patent Protection: More Generic Favored Legislation May Cause Pioneer Drug Companies To Pull The Plug On Innovation, Mandy Wilson

Kentucky Law Journal

No abstract provided.

Adrenocorticosteroid Receptor Effects On Hippocampal Neuron Viability, Deanna Lynn Mccullers

University of Kentucky Doctoral Dissertations

Glucocorticoid activation of two types of adrenocorticosteroid receptors (ACRs), themineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), influences hippocampalneuron vulnerability to injury. Excessive activation of GR may compromise hippocampalneuron survival after several types of challenge including ischemic, metabolic, and excitotoxicinsults. In contrast, MR prevents adrenalectomy-induced loss of granule neurons in the dentategyrus. The present thesis addresses the respective roles of MR and GR in modulating neuronalsurvival following two forms of neuronal injury, excitotoxicity and traumatic brain injury. MaleSprague-Dawley rats were pretreated with MR antagonist spironolactone or GR antagonistmifepristone (RU486) and subsequently injected with kainic acid, an excitotoxic glutamateanalog, or injured …

A Farm-Level Analysis Of Specialty Crop Production In Kentucky, Daniel C. Green

University of Kentucky Master's Theses

Special purpose crops are those with traits designed to meet the specificdemands of an end user. A mean-variance (E-V) mathematical programming modeland sensitivity analysis are used to quantify and discuss the potential net returns andrisk associated with the adoption of special purpose crops at the farm level.Furthermore, a spreadsheet-based decision aid is developed to assist farmers in thedecision of whether or not to produce high-oil corn on their operation.Results from this study indicate that the profitability of high-oil corn is verymarginal, dependent upon the ability of the crop to yield as well as conventional corn,and gain significant premiums. The potential …

Characterization Of Epitheliogenesis Imperfecta In Equus Caballus, Louis D. Lieto

University of Kentucky Doctoral Dissertations

Epitheliogenesis Imperfecta (EI) is a mechanobullous disease that occurs in newborn American Saddlebred and Belgian Draft foals. Necropsy evaluations of two American Saddlebred foals revealed broad skin lesions, dental abnormalities and oral mucosa lesions. Construction of a partial pedigree showing occurrences of EI in American Saddlebred horses was consistent with a recessive pattern of inheritance. An allelic frequency of 0.04 was estimated for the EI gene. The pathological signs of EI were similar to a disease in humans known as Herlitz Junctional Epidermolysis Bullosa (HJEB). HJEB is caused by a defect in one of the three subunits of the laminin …

New Input And Output Risk Management Strategies For Livestock Producers, Brian K. Coffey

University of Kentucky Master's Theses

Backgounding beef cattle is an inherently risky venture. Producers faceproduction risks as well as marketing risks. If a backgrounding operation is to be viable,these risks should be addressed and effectively managed. While some effective riskmanagement tools are currently available to livestock producers, some other potentiallyuseful risk management tools, for various reasons, have been previously unavailable.Two such tools which could help livestock producers achieve the overall goal ofmanaging net income risk are a program for managing feed ingredient nutrient and pricevariability in the selection of minimum cost feed rations and government subsidizedlivestock price insurance.Due to lack of data and limited computational …

Mechanisms Of Cd4 + T Cell Apoptosis And The Role Of Ethanol As A Cofactor In Hiv Pathogenesis, Qing Dong

University of Kentucky Doctoral Dissertations

Acquired Immunodeficiency Syndrome (AIDS) was first reported in the United States in 1981 and has since become a major worldwide epidemic. The typical course of HIV disease begins with a primary infection followed by a relatively long latency phase and finally ends in the advance phase also called AIDS. There are two aspects considered the most important in HIV pathogenesis, namely viral replication and CD4 + T cell depletion. During the latency phase, tumor necrosis factor (TNF ) has been shown to play a predominant role in HIV-1 replication and disease progression. Since ethanol is also an important risk factor …

Phosphonated Agents And Their Antiangiogenic And Antitumorigenic Use, Delwood C. Collins, Antonio Gagliardi, Peter Nickel

Obstetrics and Genecology Faculty Patents

Phosphonic acid agents are synthesized and characterized which are potent inhibitors of angiogenesis, tumorigenesis and metalloproteinase activity. Their method of use for the inhibition of angiogenesis and metalloproteinase and the treatment of tumors is also shown.

Forage News [2000-12], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Forages at KCA
• Kentucky Agricultural Statistics
• KFGC Installs New Officers
• Forage Awards Presented
• Kentucky Grazing Conference
• Small Farm Puts Stock in Managed Grazing
• Upcoming Events

Forage News [2000-11], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Statewide Grazing Conference Set for Bowling Green
• Fall Grazing School
• Three-Cornered Alfalfa Hopper
• Funding Source for Livestock/Forage Development
• Forages at KCA
• Forage Testing
• Forage Testing Has Economic Value
• Upcoming Events

Estrogen-Induced Relaxation In Bovine Coronary Arteries In Vitro: Evidence For A New Mechanism, Jelica D. J. Kalenic, Rolando J. Ramirez, Stanley Einzig, William A. Neal, Hatim A. Omar

Pediatrics Faculty Publications

Numerous studies have shown estrogen to be vasoactive in various circulations. Our objective was to determine the effect of estrogen on isolated bovine coronary arteries and the possible mechanism. Bovine coronary arteries, precontracted with thromboxane mimetic U₄₆₆₁₉ were given doses (0.01-30μM) of 17Β-estradiol in the presence and absence of endothelium and these inhibitors: 10μM indomethacin (cyclooxygenase inhibitor), 10μM methylene blue (inhibits soluble guanylate cyclase), 100μM nitro-L-arginine (inhibits nitric oxide synthesis), 100μM isobutylmethylxanthine (phosphodiesterase inhibitor) and 30μM mifepristone (Ru₃₈₄₈₆ steroid receptor antagonist). Our results indicated that, estrogen, in the highest concentration used (30μM), elicited an acute dose-dependent relaxation of …

Simulation Of Daily And Monthly Stream Discharge From Small Watersheds Using The Swat Model, Crystal A. Spruill, Stephen R. Workman, Joseph L. Taraba

Biosystems and Agricultural Engineering Faculty Publications

The Soil and Water Assessment Tool (SWAT) was evaluated and parameter sensitivities were determined while modeling daily streamflows in a small central Kentucky watershed over a two-year period. Streamflow data from 1996 were used to calibrate the model and streamflow data from 1995 were used for evaluation. The model adequately predicted the trends in daily streamflow during this period although Nash-Sutcliffe R² values were –0.04 and 0.19 for 1995 and 1996, respectively. The model poorly predicted the timing of some peak flow values and recession rates during the last half of 1995. Excluding daily peak flow values from August …

Mortality Of Escherichia Coli O157:H7 In Two Soils With Different Physical And Chemical Properties, D. N. Mubiru, Mark S. Coyne, John H. Grove

Plant and Soil Sciences Faculty Publications

Wild and domesticated animals can harbor a pathogenic Escherichia coli strain designated as O157:H7. Potential health problems could occur if strain O157:H7 is a more robust survivor in defecated waste than commonly used indicator bacteria. A laboratory study was conducted to assess E. coli O157:H7 survival relative to a nonpathogenie E. coli strain in two soils with different physical and chemical characteristics. Bacteria in the inoculated soils were enumerated on a weekly basis for 8 wk using a most probable number (MPN) technique. First-order decay models were used to describe bacteria mortality in the soils. Decay series were described slightly …

Accessory Cell Defect In Unresponsiveness Of Neonates And Aged To Polysaccharide Vaccines., Subbarao Bondada, H Wu, D A Robertson, R L Chelvarajan

Microbiology, Immunology, and Molecular Genetics Faculty Publications

T independent antigens elicit antibody responses in the absence of carrier specific T helper cells but require signals from accessory cells (macrophages and dendritic cells) or specific cytokines. They are further subdivided into TI-1 and TI-2 categories based on the ability of TI-1 but not TI-2 antigens to elicit immune responses from neonates. Most bacterial polysaccharides including the pneumococcal polysaccharide vaccines belong to the TI-2 class. It is hypothesized that defects in accessory cell function play a critical role in the failure of neonates to respond to such TI-2 antigens. Immune responses to these TI-2 stimuli are also reduced in …

Forage News [2000-10], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Fall Grazing School is On for October 16-18 in Princeton
• KFGC Awards
• Statewide Grazing Conference Set for Bowling Green
• Southern Forages Now Available on the Web
• Upcoming Events

The Toxicology Of Aluminum In The Brain: A Review, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

Aluminum is environmentally ubiquitous, providing human exposure. Usual human exposure is primarily dietary. The potential for significant Al absorption from the nasal cavity and direct distribution into the brain should be further investigated. Decreased renal function increases human risk of Al-induced accumulation and toxicity. Brain Al entry from blood may involve transferrin-receptor mediated endocytosis and a more rapid process transporting small molecular weight Al species. There appears to be Al efflux from the brain, probably as Al citrate. There is prolonged retention of a fraction of Al that enters the brain, suggesting the potential for accumulation with repeated exposure. Al …

Combination Anti-Leukimic Therapy By Utilizing Suramin And Biologic Response Modifiers, Michael A. Doukas

Internal Medicine Faculty Patents

A method of treating leukemia which includes administering an effective amount of composition comprising suramin and a biological response modifier, wherein the suramin and the biological response modifier show synergistic or additive anti-leukemic activity. A pharmaceutical composition is also disclosed.

Sarcocystis Neurona Diagnostic Primer And Its Use In Methods Of Equine Protozoal Myeloencephalitis Diagnosis, Clara K. Fenger, David E. Granstrom, Alvin A. Gajadhar, Jitender P. Dubey

Veterinary Science Faculty Patents

An amplification primer and probe which can be used in an in vitro diagnostic test for the presence of S. neurona in equine blood or cerebrospinal fluid. Sarcocystis neurona is responsible for the equine condition of protozoal myelitis. The amplification primer is seventeen nucleotides in length and complementary to a unique section of the small ribosomal subunit of Sarcocystis neurona. The primer encompasses nucleotide positions 1470-1487 of the small ribosomal subunit of S. neurona. The primer has the sequence 5' CCATTCCGGACGCGGGT SEQ ID NO:1.

Method Of Treatment Of Conditions Associate With Oxidative Tissue Damage, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing as the active ingredient a spin-trapping reagent, preferably α-phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclosed for treating or preventing symptoms associated with aging or other conditions associated with oxidative tissue damage. Other spin-trapping agents can also be used, such as 5,5-dimethyl pyrroline N-oxide (DMPO) or α-(4-pyridyl 1-oxide)-N-tert-butylnitrone (POBN), and other spin-trapping derivatives thereof. These compositions and methods are useful in the treatment of age-related disorders, pre-surgical and/or pre-anesthetic preparation or administration of chemotherapeutic agents, and in the treatment of disorders or trauma of the brain, …

Pathogen-Inducible Regulatory Element, Joseph Chappell, Catherine A. G. Cornett, Shauhui Yui

Pharmaceutical Sciences Faculty Patents

Qualitative transcriptional regulatory sequences functional in plants, plant tissue and in plant cells for inducible gene expression and quantitative transcriptional regulatory sequences for increasing the transcriptional expression of downstream genetic information in plants, plant tissue and plant cells are disclosed. Also disclosed are methods and recombinant DNA molecules for improving the disease resistance of transgenic plants, especially wherein an inducible promoter controls the expression of a protein capable of evoking the hypersensitive response in a plant.

Phosphonated Agents And Their Antiangiogenic And Antitumorigenic Use, Delwood C. Collins, Antonio Gagliardi, Peter Nickel

Obstetrics and Genecology Faculty Patents

Phosphonic acid agents are synthesized and characterized which are potent inhibitors of angiogenesis, tumorigenesis and metalloproteinase activity. Their method of use for the inhibition of angiogenesis and metalloproteinase and the treatment of tumors is also shown.

Forage News [2000-08], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Southern Beef Day Set for October 6 in Somerset
• Late Summer Forage Establishment
• Hay Contest Can Mean Big Bucks at Southern Beef Day
• AFGC Conference
• Extending Pasture Through Stockpiling
• Upcoming Events